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Embryology, anatomy and physiology of the liver: Review 肝脏的胚胎学、解剖学和生理学:综述
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.031
Komang Trisna Sumadewi
The liver, located within the peritoneal cavity, is in the right upper quadrant of the abdomen. Additionally, it should be noted that the liver holds the distinction of being the largest gland within the human body, as well as the most extensive visceral tissue situated within the abdominal cavity. One of the factors contributing to the early migration of the developing intestines to an extracoelomic location during fetal development is their relatively bigger size in children, weighing between 1400 and 1800 g in adults. It contributes to the development of a distended abdomen in pediatric populations. The liver is situated in the right upper quadrant of the abdomen and spans across the midline to the left upper quadrant. The heart remains susceptible to regular injuries despite the protective presence of ribs and cartilage. The liver, functioning as an accessory organ in digestion, undertakes several metabolic processes, including drug metabolism, bile production, and bilirubin synthesis, alongside numerous other functions. For a considerable period, medical professionals and anatomists have encountered challenges in comprehending the complex functions of the liver. Significant advancements in the comprehension of liver anatomy have contributed significantly to the notable progress observed in various surgical and interventional radiologic procedures involving hepatic artery infusion pumps, liver ablation, transplantation, transarterial chemoembolization, selective internal radiation therapy, and portal vein embolization. The existence of hepatic structure is crucial for developing and implementing gradual therapies. This page aims to provide an academic overview of the embryology, anatomy, and function of the liver.
肝脏位于腹膜腔内,位于腹部右上象限。此外,应该指出的是,肝脏是人体中最大的腺体,也是位于腹腔内最广泛的内脏组织。在胎儿发育期间,导致发育中的肠道早期迁移到肠外位置的因素之一是儿童的肠道相对较大,成人的体重在1400至1800克之间。它有助于发展膨胀的腹部在儿科人群。肝脏位于腹部右上象限,横跨中线至左上象限。尽管有肋骨和软骨的保护,心脏仍然容易受到常规损伤。肝脏在消化过程中起辅助器官的作用,承担多种代谢过程,包括药物代谢、胆汁产生和胆红素合成,以及许多其他功能。在相当长的一段时间里,医学专业人员和解剖学家在理解肝脏的复杂功能方面遇到了挑战。对肝脏解剖的理解有了显著的进步,在肝动脉灌注泵、肝消融、移植、经动脉化疗栓塞、选择性内放疗和门静脉栓塞等各种外科和介入放射治疗中取得了显著的进展。肝脏结构的存在对于发展和实施渐进式治疗至关重要。本页旨在提供胚胎学,解剖学和肝脏功能的学术概述。
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引用次数: 0
Craniosynostosis with scaphocephaly-embryological basis and clinical relevance 颅缝闭合与颅头畸形-胚胎学基础及临床相关性
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.045
Mouna Subbaramaiah, None Vyshak B N
Craniosynostosis with scaphocephaly-embryological basis and clinical relevance - IJCAP- Print ISSN No: - 2394-2118 Online ISSN No:- 2394-2126 Article DOI No:- 10.18231/j.ijcap.2023.045, Indian Journal of Clinical Anatomy and Physiology-Indian J Clin Anat Physiol
颅缝闭合与颅头畸形-胚胎学基础和临床相关性- IJCAP- Print ISSN No:- 2394-2118 Online ISSN No:- 2394-2126文章DOI:- 10.18231/ j.j IJCAP .2023.045,印度临床解剖与生理杂志-印度J临床解剖物理
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引用次数: 0
Accessory mental foramen: A peerless anatomical entity 副精神孔:一个无与伦比的解剖实体
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.039
Priyam Mitra, Kiran Radder, Poorvi Ghanti, Denis Jacob Kurian, Anil Kumar Desai
The accessory mental foramen is an uncommon phenomenon with anatomical significance. Additional foramina pattern is a rare occurrence in which only one of the foramen is regarded as the mental foramen and the others as accessory mental foramen (AMF). The emerging patterns of the mental nerve have previously been observed. This case report describes an auxiliary mental foramen that was discovered in a face trauma patient with a mandibular right parasymphysis fracture.
副颏孔是一种罕见的现象,具有解剖学意义。附加孔模式是一种罕见的情况,其中只有一个孔被认为是精神孔,而其他孔被认为是副精神孔(AMF)。精神神经的新模式以前已经被观察到。这个病例报告描述了一个辅助精神孔,是发现在一个面部创伤患者下颌骨右副骨骺骨折。
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引用次数: 0
High origin of radial artery in mid-arm and possible complications: A cadaveric case study 中臂桡动脉高起点及可能的并发症:一例尸体病例研究
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.040
Pankaj Kumar Rathi
The radial artery is a vital vessel supplying the forearm and hand. Variations in its origin can occur, leading to potential complications during clinical procedures. This cadaveric case study investigates the high origin of the radial artery in the mid-arm and its associated complications. Two cadaveric specimens were examined, at Department of Anatomy, Maulana Azad Medical College, New Delhi, and the anatomical variations were documented. The study highlights the importance of recognizing such variations and their implications in clinical practice, aiding healthcare professionals in minimizing procedural complications and optimizing patient outcomes. The tortuous course and kinking observed in this study may predispose the artery to thrombosis, spasm, or occlusion, potentially leading to ischemic complications in the forearm and hand.
桡动脉是供应前臂和手的重要血管。其来源的变化可能发生,导致临床过程中潜在的并发症。本尸体病例研究探讨了桡动脉在手臂中部的高起点及其相关并发症。在新德里Maulana Azad医学院解剖系对两具尸体标本进行了检查,并记录了解剖变异。该研究强调了认识到这些变化及其在临床实践中的意义的重要性,帮助医疗保健专业人员最大限度地减少手术并发症和优化患者结果。在本研究中观察到的弯曲路线和扭结可能使动脉易于形成血栓、痉挛或闭塞,潜在地导致前臂和手部的缺血性并发症。
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引用次数: 0
Peer assessment: An effective tool to modify professional behaviour of undergraduate medical students 同伴评估:一种有效的工具来改变本科医学生的职业行为
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.030
Anu Sharma, Rima Dada
Peer assessment: An effective tool to modify professional behaviour of undergraduate medical students - IJCAP- Print ISSN No: - 2394-2118 Online ISSN No:- 2394-2126 Article DOI No:- 10.18231/j.ijcap.2023.030, Indian Journal of Clinical Anatomy and Physiology-Indian J Clin Anat Physiol
同行评估:一个有效的工具来修改本科医学生的专业行为- IJCAP-印刷ISSN号:- 2394-2118在线ISSN号:- 2394-2126文章DOI:- 10.18231/ j.j IJCAP .2023.030,印度临床解剖与生理杂志-印度J临床解剖物理
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引用次数: 0
Patent umbilical artery in medial umbilical fold: Cadaveric study and clinical implications 脐内侧襞脐动脉未闭:尸体研究及临床意义
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.036
Neerja Rani, Parul Kaushal, Rima Dada, Sanjay Kumar, Kusuma Harisha, Seema Singh
Minimally invasive surgery has become one of the most accepted surgical options across the globe. In most laparoscopic surgeries, medial umbilical fold (MUF) containing the umbilical artery (UA) serves as an important landmark for creation of peritoneal flap. 50% of gynaecological laparoscopic injuries occur at the time of entry into the anterior abdominal wall, as it involves blind insertion of the trochar or veress needle in the peritoneal cavity. Any variation in the structures of the anterior abdominal wall may affect the placement location of the trocar, which is a crucial aspect to ease the surgeon’s ability to manoeuvre the abdominal cavity. The presence of cords and/or dense ligamentous structures in the anterior abdominal wall may complicate trocar insertion and restrict the probe movement during laparoscopic procedures. Hence, the aim of the present study was to classify and observe the variations in the MUF in the anterior abdominal wall. The cadavers in the study were formalin fixed through femoral artery perfusion method. Out of the 35 (23 males; 12 female) cadavers (70 MUF), studied, 34 cadavers (69 MUF) followed the pattern of the existing classification proposed by Tokar and Yucel, (2009). However, the right MUF of one male cadaver presented, patent umbilical artery (PUA) associated with a long mesentery. Based on safe presentations for laparoscopic exploration, MUF was given grades. Grades 0 and 1 were categorised as safe as compared to grade 2 and the novel variant observed, based on the morphology of MUF. No significant difference was noted in the occurrence of safe presentations of MUF amongst males and females. MUF with a patent vessel and a mesentery may cause technical difficulties to the surgeon by decreasing the laparoscopic port work space and obscuring the view of lateral pelvic wall during surgeries. Furthermore, persistent UA can compress the ureter and vas deferens resulting in myriad of symptoms ranging from unexplainable flank pain, hydronephrosis to male infertility. Awareness of such variants is of relevance to urologists in determining the cause of these unexplained symptoms and to surgeons in determining the site of safe trocar insertion. The findings also, highlight the fact that anterior abdominal wall anatomy is not mirror image on both the sides.
微创手术已成为全球最受欢迎的手术选择之一。在大多数腹腔镜手术中,包含脐动脉(UA)的内侧脐带褶(MUF)是腹膜皮瓣形成的重要标志。50%的妇科腹腔镜损伤发生在进入前腹壁时,因为它涉及在腹膜腔中盲插入转子或veress针。前腹壁结构的任何变化都可能影响套管针的放置位置,这是外科医生操纵腹腔能力的一个关键方面。在腹腔镜手术中,前腹壁存在绳索和/或致密的韧带结构可能使套管针的插入复杂化并限制探针的移动。因此,本研究的目的是对前腹壁MUF的变化进行分类和观察。采用股动脉灌注法对尸体进行福尔马林固定。在35人中(23名男性;研究了12具女性尸体(70具MUF), 34具尸体(69具MUF)遵循Tokar和yuel(2009)提出的现有分类模式。然而,一名男性尸体的右侧MUF表现为脐动脉未闭(PUA)伴长肠系膜。基于腹腔镜探查的安全表现,对MUF进行评分。与2级相比,0级和1级被归类为安全,根据MUF的形态观察到新的变异。在男性和女性中,MUF的安全表现没有显著差异。具有通畅血管和肠系膜的MUF可能会给外科医生带来技术上的困难,因为它减少了腹腔镜下的工作空间,并在手术中模糊了骨盆外壁的视野。此外,持续性UA可压迫输尿管和输精管,导致各种症状,从无法解释的侧腹疼痛、肾积水到男性不育。了解这些变异对泌尿科医生确定这些无法解释的症状的原因和外科医生确定安全套管针插入的位置具有重要意义。研究结果还强调了前腹壁解剖不是两侧镜像的事实。
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引用次数: 0
Assessment of learning styles using VARK model in first year undergraduate medical students 用VARK模型评价医学生一年级学习风格
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.037
Vikram Gowda N R, Nisha Kurian
In the assimilation and processing of information, students favor different choices. Fleming described the VARK learning style model that includes a questionnaire which enables us to recognize a person’s sensory modality preference in learning. It categorizes the learning styles into four: visual (V), aural (A), read/write (R), and kinesthetic (K). 1) To assess the learning styles of first year MBBS students of a Private Medical College in Kerala and find out prevalence of unimodal and multimodal learners. 2) To find association between scores of students in anatomy, biochemistry and physiology and their VARK categories. 3) To determine the association between gender and VARK categories. A cross-sectional self-administered questionnaire survey was conducted among first year undergraduate medical students in a private medical college in Kerala. VARK questionnaire, consists of 16 multiple choice questions, was distributed to the participants after obtaining written consent. Scores of their internal assessment were also collected. The data was analyzed and the learning styles were presented as percentages. Chi-square test, Mann-Whitney U test, and Kruskal-Wallis tests were used to find the association between learning styles and gender, and the scores in internal assessment. The total number of students enrolled for the study was100. Age ranged from 17 to 22 years and females constituted 62%. It was observed that 84% students were unimodal, out of which Kinesthetic (45.2%) was the most preferred. There were 12 bimodal and 4 trimodal learners. No association between learning styles and gender as well as between learning styles and academic performance based on written and practical exams of Anatomy, Physiology and Biochemistry were found. We found there were notable differences between males and females in unimodal kinesthetic and auditory learners in certain scores. The present study reported that unimodal learners were more frequent than bimodal and trimodal learners. There were no quadrimodal learners. The preferred method of learning amongst unimodal learners was the kinesthetic style. We found no association between gender and the preferred learning style. The study also found that there was no association between academic performance (scores) and their learning styles.
在信息的同化和加工过程中,学生倾向于不同的选择。弗莱明描述了VARK学习风格模型,该模型包括一个问卷,使我们能够识别一个人在学习中的感官形态偏好。它将学习风格分为四种:视觉(V),听觉(A),读/写(R)和动觉(K)。1)评估喀拉拉邦一所私立医学院一年级MBBS学生的学习风格,并找出单模态和多模态学习者的患病率。2)发现学生解剖、生物化学和生理学成绩与其VARK分类之间的关系。3)确定性别与VARK类别之间的关系。对喀拉拉邦一所私立医学院的一年级本科生进行了横断面自填问卷调查。VARK问卷由16道选择题组成,在获得参与者书面同意后分发给参与者。还收集了他们的内部评估分数。对数据进行分析,并以百分比表示学习风格。采用卡方检验、Mann-Whitney U检验和Kruskal-Wallis检验,发现学习风格与性别、内部测评成绩之间的关系。参加这项研究的学生总数为100人。年龄17 - 22岁,女性占62%。我们观察到84%的学生是单峰的,其中动觉的(45.2%)是最受欢迎的。双峰学习者12人,三峰学习者4人。在解剖学、生理学和生物化学的书面和实践考试中,没有发现学习方式和性别之间的联系,也没有发现学习方式和学习成绩之间的联系。我们发现男女在单峰动觉型和听觉型学习者的某些分数上存在显著差异。本研究报告单峰学习者比双峰学习者和三峰学习者更频繁。没有四模态学习者。单模学习者首选的学习方法是动觉风格。我们发现性别和偏好的学习方式之间没有联系。研究还发现,学习成绩(分数)和学习方式之间没有关联。
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引用次数: 0
Demystifying anatomical variations- Education and clinical perspectives 揭开解剖变异的神秘面纱-教育和临床观点
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.044
Vivek Mishra, Mrinal Barua, Shelja Sharma, Prerna Chandra
The plethora of anatomical variations in scientific literature has made it very difficult for health care professionals like surgeons and interventionists to remember anatomical variations during the procedure and there are high chances that the variations they are going to find during a procedure will always be different from the one that is already reported in some or the other way. Finding similarities and dissimilarities with previously reported versions of variations entirely depends on experience and education of interventionists. The continuous addition of variations on one side adding to our existing scientific knowledge but on other side It is almost impractical and herculean task to remember all variations and continuous addition making it more difficult to distinguish the significant from not so significant facts and apply these facts in clinical practice. Evidence based Anatomy can do justice to this situation but robust studies related to anatomical variations are still lacking as we have plenty of case reports related to anatomical variations having many scientific flaws. As an academic exercise reporting anatomical variations may be fine but in the real world such things cause confusion and affect decision-making. We must try and learn to draw a line and avoid adding gibberish to scientific literature as an extension of our professed moral duty towards science.
科学文献中过多的解剖变异使得像外科医生和介入医生这样的卫生保健专业人员很难在手术过程中记住解剖变异,而且他们在手术过程中发现的变异很有可能总是与已经以某种或其他方式报道的不同。发现与先前报道的变异版本的异同完全取决于干预者的经验和教育。一方面,不断增加的变化增加了我们现有的科学知识,但另一方面,记住所有的变化和不断增加的变化几乎是不切实际和艰巨的任务,这使得区分重要的事实和不那么重要的事实并将这些事实应用于临床实践变得更加困难。基于证据的解剖学可以公正地对待这种情况,但由于我们有大量与解剖学变异相关的病例报告存在许多科学缺陷,因此仍然缺乏与解剖学变异相关的强有力的研究。作为一种学术练习,报告解剖变异可能没问题,但在现实世界中,这样的事情会造成混乱,影响决策。我们必须试着学会划清界限,避免在科学文献中添加胡言乱语,作为我们对科学所宣称的道德责任的延伸。
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引用次数: 0
A systematic review on physiological role of yoga and pranayama in management of orthostatic hypotension and vasovagal syncope 瑜伽和调息在治疗体位性低血压和血管迷走神经性晕厥中的生理作用的系统综述
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.033
None Balaji P A, Smitha R Varne
OH and VVS are increasingly recognized as important causes of impairment of quality of life and potentially of poor prognosis. Existing management therapies have modest effect. Recently few studies have emerged and have demonstrated the efficacy of yoga and pranayama in disorders having autonomic imbalance, suggesting its possible efficacy in OH and VVS. This review aims to determine the effectiveness of yogic practices in patients with orthostatic hypotension (OH) and recurrent vasovagal syncope (VVS). A Medline search was done in Google chrome to review relevant articles in English literature considering the eligibility criteria that the article should focus on yoga and pranayama and its physiological effects on OH and VVS. The main outcome expected was attenuation of OH and frequency of attacks of syncope and presyncope. : Out of the total 86 articles searched, 7 articles (3 RCTs, 3 observational/interventional, 1 review) full filled the eligibility criteria and depicted that yogic practices can have positive impact in attenuation of orthostatic hypotension and reduce the frequency of attacks of syncope and presyncope, among patients with recurrent VVS. However, we recommend higher-quality RCTs in future to confirm our results.
OH和VVS越来越被认为是生活质量受损和潜在预后不良的重要原因。现有的管理疗法效果一般。最近有一些研究表明瑜伽和调息对自主神经失衡的疾病有疗效,提示其可能对OH和VVS有疗效。本综述旨在确定瑜伽练习对直立性低血压(OH)和复发性血管迷走神经性晕厥(VVS)患者的有效性。在Google chrome浏览器中进行Medline搜索,回顾英文文献中的相关文章,考虑文章的资格标准,即文章应侧重于瑜伽和调息及其对OH和VVS的生理影响。预期的主要结果是OH的衰减和晕厥和晕厥前期发作的频率。在检索到的86篇文章中,有7篇(3篇随机对照试验,3篇观察性/干预性研究,1篇综述)完全符合入选标准,并描述了瑜伽练习在复发性VVS患者中对降低体位性低血压和减少晕厥和晕厥前期发作频率有积极影响。然而,我们建议将来进行更高质量的随机对照试验来证实我们的结果。
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引用次数: 0
A case report on multiple accessory muscles and nerve variations in upper limb 上肢多副肌及神经变异1例
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.041
Priyanka Clementina Stephen, Nikilesh Sankaran, Ambiga Raman, Suman Verma, Aravindhan Kishore
During routine dissection of formalin fixed cadavers, the brachial plexus and other upper limb structures were observed for variations. In 65-year-old male cadaver, bilateral upper limb neuromuscular variations were identified. On the left side, median nerve had three roots (one medial and two lateral) and biceps brachii had an additional head which was originating from the mid shaft of humerus and joined with the main muscle at the lower third of arm, and was innervated by musculocutaneous nerve. On the right side, the brachioradialis muscle had an accessory head which took origin from the lateral side of humerus near deltoid tuberosity and joined with main tendon in the lower part of the forearm, and was innervated by radial nerve. The association of nerve variations and accessory muscles is clinically significant. As accessory muscle may lead to nerve or artery entrapment in the limb and is likely to cause palsy or ischemia, knowledge about the neuromuscular variations is clinically significant.
在常规解剖福尔马林固定尸体时,观察臂丛和其他上肢结构的变化。在65岁男性尸体中,发现双侧上肢神经肌肉变异。在左侧,正中神经有三根(一根内侧和两根外侧),肱二头肌有一个额外的头,起源于肱骨中轴,与手臂下三分之一的主肌连接,受肌肉皮神经支配。右侧肱桡肌有一副头,起源于肱骨外侧近三角粗隆处,与前臂下端主腱相连,受桡神经支配。神经变异和副肌的关联在临床上具有重要意义。由于副肌可引起肢体神经或动脉的卡压,并可能引起瘫痪或缺血,因此了解其神经肌肉变异在临床上具有重要意义。
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引用次数: 0
期刊
Indian journal of clinical anatomy and physiology
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