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Assessing the histomorphology, and microscopic composition of the triangular fibrocartilage complex [TFCC] of the wrist joint: A cadaveric observational study 评估腕关节三角纤维软骨复合体 [TFCC] 的组织形态学和显微构成:尸体观察研究
Pub Date : 2024-01-15 DOI: 10.18231/j.ijcap.2023.054
V. D. Kumar, Nandini Rajaram
TFCC, being a complicated structure, located on the ulnar side of the wrist is composed of multiple distinct anatomic entities which together play a critical role in wrist biomechanics. The anatomy of TFCC has not been extensively studied in the Indian population. To elucidate the microscopic anatomy and composition of the triangular fibrocartilage complex of the wrist joint using haematoxylin-eosin and Verhoff Van Gieson staining methods. Samples collected from 40 specimens (20 right and 20 left limbs) were placed in 10% neutral buffered formalin for fixation. Paraffin-embedded blocks were prepared and tissue sections were taken at 7-micron thickness. The slides were subjected to H&E and VVG staining following standardized protocol. The morphological structure of the seven components of triangular fibrocartilage complexes was assessed. The articular disc consisted of densely packed interlaced fibrocartilage with sparse blood vessels. Radioulnar ligaments showed densely-packed-parallel or interlaced- collagen-bundles. A mixture of tight and loose parallel tissue was observed in the sub-sheath of the extensor carpi ulnaris muscle, the ulnar-triquetral (UTL), and the ulnar-lunate ligament (ULL). Irregular morphological composition and loose connective tissue predominated in the ulnar-carpal meniscus (UCM). Blood vessels were observed in the epi-fascicular/ fascicular areas of the UTL, interstitial region of ULL and UCM. The microscopic anatomy of TFCC was complex owing to the varied nature of its entities. An understanding of the distribution of connective tissue, blood vessels, and elastic fibres would be of immense help in planning arthroscopic procedures.
位于腕部尺侧的 TFCC 结构复杂,由多个不同的解剖实体组成,共同在腕部生物力学中发挥着重要作用。印度人尚未对 TFCC 的解剖结构进行广泛研究。本研究采用血色素-伊红和 Verhoff Van Gieson 染色法,阐明腕关节三角纤维软骨复合体的显微解剖结构和组成。从 40 个标本(20 个右肢和 20 个左肢)中采集的样本放入 10% 中性缓冲福尔马林中固定。制备石蜡包埋块,并制作 7 微米厚的组织切片。切片按照标准化方案进行 H&E 和 VVG 染色。对三角形纤维软骨复合体七个组成部分的形态结构进行了评估。关节盘由密集交错的纤维软骨组成,血管稀疏。桡侧韧带显示出密集的平行或交错胶原束。在尺骨伸肌鞘下、尺骨-三股韧带(UTL)和尺骨-月骨韧带(ULL)中可观察到紧密和疏松的混合平行组织。尺-腕半月板(UCM)的形态组成不规则,结缔组织疏松。在尺桡韧带外筋膜/筋膜区、尺桡韧带间隙区和尺桡半月板间隙区观察到血管。由于 TFCC 的实体性质各不相同,因此其显微解剖非常复杂。了解结缔组织、血管和弹性纤维的分布将对关节镜手术的规划大有帮助。
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引用次数: 0
A case report on the bilateral absence of fourth tendinous slip of the flexor digitorum brevis muscle in the foot: Exploring evolutionary and surgical relevance 关于足部屈指肌第四腱滑脱双侧缺失的病例报告:探索进化与手术的相关性
Pub Date : 2024-01-15 DOI: 10.18231/j.ijcap.2023.058
Sipra Rout, Archishnu Vedanta Parida, Devendra Pal Singh
The flexor digitorum brevis (FDB) muscle extends across the central region of the sole, positioned deep beneath the plantar aponeurosis. It inserts into the lateral four toes through four slender musculotendinous slips. Functionally, this muscle reinforces the foot arch by facilitating flexion at the interphalangeal and metatarsophalangeal joints of the lateral toes. In clinical contexts, the FDB muscle serves as a musculocutaneous flap in reconstructive surgeries, addressing various foot deformities. Despite its small size, the FDB muscle carries significant evolutionary importance, indicating potential phylogenetic degeneration in humans due to adaptations to diverse lifestyles. The anatomical variation presented in this case report holds importance, as the presence or absence of the FDB muscle can play a crucial role in maintaining arch integrity and holds relevance from a surgical perspective.
趾屈肌(FDB)横跨足底中央区域,位于跖腱膜下方深处。它通过四条细长的肌肉腱索插入四个脚趾的外侧。在功能上,这块肌肉通过促进外侧脚趾的指间关节和跖趾关节的屈曲来加固足弓。在临床上,FDB 肌肉可作为重建手术中的肌皮瓣,用于治疗各种足部畸形。尽管 FDB 肌肉的体积很小,但它在进化过程中具有重要意义,表明人类由于适应不同的生活方式而可能出现系统发育退化。本病例报告中的解剖变异具有重要意义,因为 FDB 肌肉的存在与否在维持足弓完整性方面起着至关重要的作用,从外科角度来看也具有相关性。
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引用次数: 0
Risk factors of non communicable diseases among recently diagnosed diabetic patients in a tertiary care Hospital 一家三级医院新近确诊的糖尿病患者罹患非传染性疾病的风险因素
Pub Date : 2024-01-15 DOI: 10.18231/j.ijcap.2023.048
Yusra Amin, Sonia Mushtaq, Rukhsana Farooq
There are many risk factors which determine the development of complications among diabetic patients, some of which are modifiable and some non modifiable. Further, taking care of risk factors and controlling other non-communicable diseases among diabetics will defer the complications due to diabetes.To look for distribution of non-communicable disease risk factors among the diabetic patients. : The present cross-sectional study was conducted in Government Medical College & Hospital Jammu from 2019 to 2020. All the recently diagnosed patients (<1 year duration) of type 2 DM who were of ≥ 18 years of age, both males and females and were willing to participate in the study were included. Overall 70 recently diagnosed diabetic patients both males and females attended outpatient department of General Medicine of the Associated Hospital of the college during the study period.: The mean age in study group was 48.9±11.78 years [30-75] years with a mean BMI of 24.3±3.28 kg/m. 22 patients [31.4%] were smokers; hypertension was seen in 13 patients [18.6%]; hypothyroidism in 4 patients [5.7%]; rheumatoid arthritis in 2 patients [2.9%] and epilepsy in 2 patients [2.9%]. Family history of diabetes was present in 29 patients [41.4%] and dyslipidemia in 12 patients [17.1%]. 31 patients [44.3%] had normal glycemic control with Hba1c of less than 7 while as 39 patients [55.7%] had poor glycemic control with Hba1c of greater than 7.: Significant proportion of the participants in our study had one or more risk factor present the development of a chronic disease or where suffering already from a non-communicable disease.
决定糖尿病患者并发症发生的风险因素有很多,其中有些是可改变的,有些是不可改变的。此外,关注糖尿病患者的风险因素并控制其他非传染性疾病将推迟糖尿病并发症的发生。 本横断面研究于 2019 年至 2020 年在查谟政府医学院和医院进行。研究对象包括所有新近确诊的 2 型糖尿病患者(病程小于 1 年),这些患者年龄≥ 18 岁,既有男性也有女性,并且愿意参与研究。在研究期间,共有 70 名新近确诊的糖尿病患者在该学院附属医院普通内科门诊就诊,其中既有男性也有女性:研究组的平均年龄为 48.9±11.78 岁[30-75],平均体重指数为 24.3±3.28 kg/m。22名患者[31.4%]吸烟;13名患者[18.6%]患有高血压;4名患者[5.7%]患有甲状腺功能减退症;2名患者[2.9%]患有类风湿性关节炎;2名患者[2.9%]患有癫痫。29 名患者[41.4%]有糖尿病家族史,12 名患者[17.1%]有血脂异常家族史。31 名患者[44.3%]血糖控制正常,Hba1c 小于 7,而 39 名患者[55.7%]血糖控制不佳,Hba1c 大于 7:在我们的研究中,很大一部分参与者都有一种或多种导致慢性疾病发生的危险因素,或者已经患有非传染性疾病。
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引用次数: 0
Anatomical variations of the brachiocephalic artery and their clinical relevances: A cadaveric study of Ugandan population 肱动脉的解剖变异及其临床意义:乌干达人口尸体研究
Pub Date : 2024-01-15 DOI: 10.18231/j.ijcap.2023.056
Andrew Emmanuel Tito, K. Obeten, V. Archibong, Ekon Monday Etukudo, Joseph Atupele Mwabaleke, I. Usman, Mario Edgar Fernandez
The study examined variations in morphology and morphometry of the brachiocephalic artery and their clinical implications in dissected cadavers. Fifty-eight (58) adult cadavers, 57 males and 1 female were dissected to expose the brachiocephalic artery, and the morphological and morphometric variations were recorded.Fifty-one (51) cadavers (88%) had the BCA arising directly from the aortic arch while 7 cadavers (12%) had it originating from the common trunk with the left common carotid artery. The BCA arose on the left anterolateral to the trachea in 57 cadavers (98.3%) and one cadaver (1.7%) had it arising in the midline anterior to the trachea crossed the trachea from left to right terminating posterior to the right sternoclavicular joint where it bifurcated into the right subclavian and right common carotid artery in all cadavers. The mean lengths of the torsos and Brachiocephalic arteries were 45.78±2.93cm and 4.14±0.58cm respectively and the two parameters had statistically significant positive correlation (r=0.33, p<0.05).: A majority of the Ugandan cadaveric population have brachiocephalic arteries with the normal origin, course, and branching patterns. The occurrence of origin variants of BCA from the common trunk and anterior midline to the trachea may be associated with tracheal compression and aortic dilation; hence should be considered as a potential risk factor for thoracic aortic aneurysm and during tracheostomy respectively.
该研究探讨了解剖尸体中肱动脉形态和形态计量的变化及其临床意义。解剖了 58 具成年尸体,其中 57 具为男性,1 具为女性,以暴露肱脑动脉,并记录了形态和形态计量的变化。51 具尸体(88%)的肱脑动脉直接起源于主动脉弓,7 具尸体(12%)的肱脑动脉起源于与左侧颈总动脉的共同主干。57具尸体(98.3%)的BCA起源于气管的左前外侧,1具尸体(1.7%)的BCA起源于气管前方的中线,从左到右穿过气管,在右胸锁关节后方终止,在所有尸体中,BCA在此处分叉为右锁骨下动脉和右颈总动脉。躯干和肱动脉的平均长度分别为(45.78±2.93)厘米和(4.14±0.58)厘米,这两个参数在统计学上具有显著的正相关性(r=0.33,p<0.05):大多数乌干达尸体中的肱动脉具有正常的起源、走向和分支模式。肱动脉从总干和气管前中线的起源变异可能与气管受压和主动脉扩张有关,因此应分别视为胸主动脉瘤和气管切开术的潜在风险因素。
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引用次数: 0
Colorimetric variations in cadaveric tissues embalmed with modified Thiel's and Formalin solutions: An objective comparative study using image J 用改良Thiel's 和福尔马林溶液防腐的尸体组织的色度变化:使用图像处理技术进行客观比较研究
Pub Date : 2024-01-15 DOI: 10.18231/j.ijcap.2023.049
Rajasekhar SSSN, Kalaivani K
The comparison of tissue colour between Thiel's embalmed cadavers (TEC) and formalin-embalmed cadavers (FEC) is crucial for assessing the efficacy of Thiel embalming technique as a suitable alternative to formalin embalming for surgical skill training and anatomical education. Most of the studies which declare the superiority of tissue colour in TEC over FEC have done subjective assessment and comparison of the tissue colour. This study aims to compare the colour difference between Thiel and formalin embalmed cadavers objectively. : The current study used six human cadavers to compare the effects of two embalming methods, Modified Thiel’s solution (MTS) and Modified Formalin Solution(MFS). The tissues of the cadavers were dissected and photographed to be analysed for Red, Blue, Green values using Image J software.  The mean (SD) R-value (Red), G-value (Green), and B-value (Blue) for MTS embalmed cadavers were 149.78 (16.070), 124 (19.675), and 109.96 (9.852), respectively, from pictures of embalmed cadavers from research groups. The mean RGB value of MTS embalmed cadavers was substantially (P<0.05) higher than MFS embalmed cadavers.  The current research found that MTS-embalmed cadavers have greater RGB values than MFS-embalmed ones. This information helps to fully understand tissue property changes, evaluate their impact on student perceptions and learning outcomes, and determine Thiel embalming's suitability for surgical training and workshops.
比较蒂尔防腐尸体(TEC)和福尔马林防腐尸体(FEC)的组织颜色对于评估蒂尔防腐技术作为外科技能培训和解剖学教育中福尔马林防腐技术的合适替代品的有效性至关重要。大多数宣称蒂尔防腐技术的组织颜色优于福尔马林防腐技术的研究都对组织颜色进行了主观评估和比较。本研究旨在客观比较泰尔和福尔马林防腐尸体的颜色差异。 本研究使用六具人体尸体,比较两种防腐方法(改良泰尔溶液(MTS)和改良福尔马林溶液(MFS))的效果。对尸体组织进行解剖和拍照,并使用 Image J 软件对红、蓝、绿值进行分析。 从研究小组的防腐尸体图片中得出,MTS防腐尸体的平均(标清)R值(红色)、G值(绿色)和B值(蓝色)分别为149.78(16.070)、124(19.675)和109.96(9.852)。MTS 防腐尸体的平均 RGB 值大大高于 MFS 防腐尸体(P<0.05)。 目前的研究发现,经 MTS 防腐处理的尸体比经 MFS 防腐处理的尸体具有更高的 RGB 值。这些信息有助于充分了解组织属性的变化,评估其对学生认知和学习成果的影响,并确定蒂尔防腐法是否适合外科培训和研讨会。
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引用次数: 0
Perception of medical students on the advantages and disadvantages of online assessment compared to traditional method in a tertiary level teaching hospital 一家三级教学医院的医科学生对在线评估与传统评估方法利弊的看法
Pub Date : 2024-01-15 DOI: 10.18231/j.ijcap.2023.050
Anitha Nancy, Aravinthan S, J. D. Anton, J. Raj
: The use of e-assessment/online tests have increased in higher education over the last two decades. Technology plays a positive role in students learning process and provides an opportunity to give immediate feedback. In India online mode was not used for formative/summative assessment except in fewer renowned institutions. But now it has increased recently because of COVID-19 pandemic.: This study aims to know the perception of I year MBBS students on the advantages and disadvantages of using online assessment in formative and internal assessment when compared to the traditional method.In a private medical college, Cross-sectional survey was done using standard and validated questionnaires with likert scale scoring (1-Strongly disagree, 2- Disagree, 3- Neutral, 4- Agree & 5- Strongly agree) for I year undergraduate medical students.Out of 115 students’ responses, 47.4% (36%-Agree & 11.5%- strongly agree) that online assessment has positive influence on their learning experience but only 39% were comfortable to use online assessment over traditional method and the others remained neutral (32%) and (29%) disagreed to the statement. By having online trial test and trainings 85.1% students agreed to use online assessment but still felt comfortable to use traditional method for assessment.From our study, we found that students did not prefer to switch from traditional to an online method in the form of learning or assessment. But they show their willingness to adapt to a blended assessment method.
:过去二十年来,高等教育中使用电子评估/在线测试的情况越来越多。技术在学生的学习过程中发挥了积极的作用,并提供了即时反馈的机会。在印度,除少数知名院校外,在线模式并未用于形成性/总结性评估。本研究旨在了解医学学士学位一年级学生对在形成性评估和内部评估中使用在线评估与传统方法相比的优缺点的看法。在一所私立医学院中,针对医学学士学位一年级学生进行了横断面调查,采用标准有效问卷,并使用李克特量表评分(1-非常不同意、2-不同意、3-中立、4-同意和 5-非常同意)。在 115 名学生的回答中,47.4%(36%-同意和 11.5%-非常同意)认为在线评估对他们的学习体验有积极影响,但只有 39% 的学生愿意使用在线评估而不是传统方法,其他学生则保持中立(32%)和不同意(29%)。通过在线测试和培训,85.1%的学生同意使用在线评估,但仍觉得使用传统评估方法更合适。但他们表示愿意适应混合式评估方法。
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引用次数: 0
Mechanism of infection of SARS-CoV-2 and gender based differential impacts SARS-CoV-2 的感染机制和基于性别的不同影响
Pub Date : 2024-01-15 DOI: 10.18231/j.ijcap.2023.061
D. Ghosh, Suvendu Ghosh, P. Singha
The world has witnessed a pandemic in the recent past. COVID-19 has been a nightmare for all. The virus SARS-CoV-2 causes the disease. The impact of the pandemic on human life and on various aspects of the society is still prevailing. No specific effective drug has yet been formulated to completely combat the virus. It took more than a year for the researchers and scientists around the globe to understand the mechanism of the virus infection. For the time being vaccines have been designed and those seems to be effective in preventing the infection to some extent. The pattern of infection by SARS-CoV-2, symptoms, pathophysiology, complications and fatality associated with COVID-19 has been found to be dependent on various factors and varies from person to person. The virus has been found to have differential mechanism of infection and impacts in male and female. The X-Chromosome plays an interesting role.
不久前,世界上发生了一场大流行病。COVID-19 是所有人的噩梦。这种疾病是由 SARS-CoV-2 病毒引起的。这一大流行病对人类生活和社会各方面的影响仍然普遍存在。至今还没有一种特效药物可以完全对付这种病毒。全球的研究人员和科学家花了一年多的时间才弄清病毒感染的机理。目前,人们已经设计出了疫苗,这些疫苗似乎在一定程度上可以有效预防感染。与 COVID-19 相关的 SARS-CoV-2 感染模式、症状、病理生理学、并发症和致死率取决于各种因素,而且因人而异。已发现该病毒对男性和女性的感染和影响机制不同。X 染色体发挥着有趣的作用。
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引用次数: 0
Grade I Meningioma in a cadaver – A case report 尸体中的 I 级脑膜瘤 - 病例报告
Pub Date : 2024-01-15 DOI: 10.18231/j.ijcap.2023.060
Shashikala Londhe, Anjali Gosavi, M. Kasegaonkar, Nilesh Bhosle
In a routine dissection of anatomy department in Ashwini Rural Medical College and Research Centre Kumbhari, Solapur, Maharashtra. While removing the brain from the cadaveric skull.Noticed a small tumor of measuring 1.3cm in length, 1.3cm in breadth and 1.2cm in height, situated at the orbital surface of the brain in the gyrus rectus of a male cadaver.In the histological study it was diagnosed as a Meningioma grade I.It was small size encapsulated tumor on inferior aspect of brain. On histological study, it showed meningo epithelial cells in whorl pattern, blood vessels, fibrous tissue Psammoma bodies, which indicate grade I meningioma.
在马哈拉施特拉邦索拉普尔的阿什维尼农村医学院和研究中心昆布哈里解剖部门的一次例行解剖中,当从尸体头骨中取出大脑时,发现一个长 1.3 厘米、宽 1.3 厘米、高 1.2 厘米的小肿瘤位于眼眶表面。在组织学研究中,该肿瘤被诊断为脑膜瘤 I 级,是位于大脑下部的小体积包裹性肿瘤。在组织学研究中,它显示了轮状的脑膜上皮细胞、血管、纤维组织和 Psammoma 体,这表明它属于 I 级脑膜瘤。
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引用次数: 0
A study on the morphology and morphometry of foramen ovale in dry human skulls 干颅骨卵圆孔的形态学和形态学研究
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.038
Prathap Kumar J, None Shivamurthy K, None Padmalatha K, Prakash B S Prakash B S, Amrita N Shamanewadi
An oval shape foramen is present in the greater wing of sphenoid through which passes the many vital structures. It is located at the transitional area between intracranial and extracranial structures. It is important for diagnostic and surgical procedures. A total 100 skulls were used for the study. 82 skulls were studied and 18 skulls were excluded from the study. The skulls were collected from Phase I MBBS students from different medical colleges in south India. Skulls in poor conditions or skulls with partly damaged surroundings of the foramen ovale were not considered. Maximum length and width of foramen ovale was measured using digital Vernier calliper. Also, the distance from the anterior root of zygoma and the distance from the articular tubercle on zygomatic arch to foramen ovale were measured. Variation in right and left side were calculated, the variations in shape also recorded. The mean length of foramen ovale was 6.8 ±1 and the mean breath of foramen ovale was 3.65±1. Two-sample independent t test showed significant difference between the right and left breadths of foramen ovale (p 0.0126), while the right and left lengths of foramen ovale were not significant (p 0.245). The mean distance of foramen ovale from articular tubercle on Zygomatic arch was 33±2 mm. The mean distance from anterior root of Zygomatic arch was 21.5 ± 2.1 mm. The present study concludes that there is significant difference between sizes of right and left side foramen ovale. Foramen ovale has practical significance to both neurosurgical and functional cranial neuroanatomy as it provides transcutaneous approaches to the skull base especially in cases of trigeminal neuralgia, as the Gasserion ganglion can be approached through it.
蝶骨的大翅上有一个椭圆形的孔,许多重要结构都通过它。它位于颅内和颅外结构之间的过渡区域。它对诊断和外科手术都很重要。这项研究总共使用了100个头骨。82个头骨被研究,18个头骨被排除在研究之外。这些头骨来自印度南部不同医学院的第一阶段MBBS学生。不考虑条件差的颅骨或卵圆孔周围部分受损的颅骨。用数字游标卡尺测量卵圆孔的最大长度和宽度。测量颧弓关节结节至卵圆孔的距离及颧前根的距离。计算了左右两侧的变化,并记录了形状的变化。卵圆孔平均长度为6.8±1,卵圆孔平均呼吸3.65±1。双样本独立t检验显示左右卵圆孔宽度差异有统计学意义(p 0.0126),左右卵圆孔长度差异无统计学意义(p 0.245)。卵圆孔距颧弓关节结节的平均距离为33±2 mm。距颧弓前根平均距离21.5±2.1 mm。本研究认为左右侧卵圆孔的大小有显著差异。卵圆孔在神经外科和功能性颅神经解剖学中都具有重要的实际意义,因为它提供了经皮进入颅底的途径,特别是在三叉神经痛的情况下,可以通过它进入Gasserion神经节。
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引用次数: 0
A rare variation of omohyoid and its embryological correlations- A case report 肩胛舌骨罕见变异及其胚胎学相关性- 1例报告
Pub Date : 2023-10-15 DOI: 10.18231/j.ijcap.2023.043
Prerna Chandra, Vivek Mishra, Shelja Sharma
The omohyoid muscle is important in radical neck dissection, as it is a landmark for this operation. Because it divides the anterior and posterior cervical triangles into smaller triangles and its particular relationship to the large cervical vessels, the presence of an anatomical variation of the omohyoid muscle is important. Either belly may be absent or double; and the inferior belly may be attached directly to the clavicle and the superior is sometimes fused with sternohyoid. Variations in the omohyoid muscle might be linked to differences in embryological development, which could influence the muscle’s final form and function. Anderson (Anderson, 1881) theorized that the superior belly of the omohyoid muscle is a true infrahyoid muscle, whereas the inferior belly most likely shares a common embryology with the subclavius muscle. As omohyoid mucle is used to achieve the reconstruction of the laryngeal muscles and bowed vocal folds, the knowledge of the possible anomalies of the omohyoid muscle is important. In the present study, we have found a case with two inferior bellies & aberrant course of superior belly of omohyoid on right side of 40 years female cadaver embalmed with formalin during routine dissection at Department of Anatomy AIIMS Gorakhpur. Omohyoid muscle is closely related to large vessels of neck & brachial plexus, so variations in this muscle are clinically important.
肩胛舌骨肌在根治性颈部清扫术中很重要,因为它是该手术的标志。因为肩胛舌骨肌将颈椎前后三角分割成更小的三角以及它与大的颈椎血管的特殊关系,所以肩胛舌骨肌解剖变异的存在是很重要的。腹部可无或重瓣;下腹部可能直接与锁骨相连上腹部有时与胸舌骨融合。肩胛舌骨肌的变异可能与胚胎发育的差异有关,这可能会影响肌肉的最终形态和功能。Anderson (Anderson, 1881)认为肩胛舌骨肌的上腹是真正的舌骨下肌,而下腹很可能与锁骨下肌具有共同的胚胎学。由于使用肩胛舌骨肌来实现喉肌和弓形声带的重建,因此了解肩胛舌骨肌可能的异常是很重要的。在本研究中,我们发现了一个有两个下腹部的病例。戈拉克布尔医科大学解剖科常规解剖40岁女性尸体时右侧肩胛舌骨上腹部异常。肩胛舌骨肌与颈部大血管密切相关;臂丛,所以这种肌肉的变化在临床上很重要。
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引用次数: 0
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Indian journal of clinical anatomy and physiology
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