Background: COVID-19 is a disease caused by a new coronavirus called SARS-CoV-2. In more severe cases, COVID-19 can cause death. The most severe COVID-19 patient mortality is associated with underlying health conditions. The most common associated comorbidities are pulmonary disease, diabetes, obesity, and old age. However, the effects of obesity and T2DM disease on the 2019 coronavirus disease (COVID-19) pandemic are controversial. This study aims to analyze the magnitude of the influence of obesity and T2DM on COVID-19 mortality. Subjects and Method: This study uses a systematic review and meta-analysis research design. The time of the selected test results is between January 2020 to January 2021. The search for articles is carried out for 1 month. Research data was searched from databases: PubMed, Google Scholar, JAMA, Willey, and Science Direct. Using search keywords: (Type 2 diabetes mellitus OR diabetic) AND (mortality OR death) AND (COVID-19 /OR Coronavirus OR SARS-CoV-2) AND ("adjusted odds ratio" OR "aOR"), (obesity OR obese) AND (mortality OR death) AND (COVID-19 OR Coronavirus OR SARS-CoV-2) AND ("adjusted odds ratio" OR "aOR"). The inclusion criteria in this study were full-text articles in English, observational study designs were collected using PRISMA, and analyzed using the Review Manager application (RevMan 5.3). Results: A total of 15 articles were reviewed in this study. A meta-analysis of 10 cohort studies showed that people with COVID19 who had comorbid obesity were 1.50 times more likely to die from COVID-19 compared to those without obesity (aOR = 1.50; 95% CI = 1.17 to 1.93; p = 0.001). A meta-analysis of 6 cohort studies showed people with COVID-1919 who had comorbid T2DM 1.93 times to die from COVID-19 compared with those without T2DM (aOR = 1.93; 95% CI = 1.28 to 2.90; p = 0.002). Conclusion: Obesity and T2DM are predictors of COVID19 mortality. Keywords: obesity, type 2 diabetes mellitus, mortality, COVID 19 Correspondence: Oktaviana Kurniawati. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: oktaniawati94@gmail.com. Mobile: 085865463742. Journal of Epidemiology and Public Health (2021), 06(02): 177-191 https://doi.org/10.26911/jepublichealth.2021.06.02.05
{"title":"Meta-Analysis the Effects of Obesity and Type 2 Diabetes Mellitus on Covid-19 Mortality","authors":"Oktaviana Kurniawati, Hanung Prasetya, Bhisma Murti","doi":"10.26911/jepublichealth.2021.06.02.05","DOIUrl":"https://doi.org/10.26911/jepublichealth.2021.06.02.05","url":null,"abstract":"Background: COVID-19 is a disease caused by a new coronavirus called SARS-CoV-2. In more severe cases, COVID-19 can cause death. The most severe COVID-19 patient mortality is associated with underlying health conditions. The most common associated comorbidities are pulmonary disease, diabetes, obesity, and old age. However, the effects of obesity and T2DM disease on the 2019 coronavirus disease (COVID-19) pandemic are controversial. This study aims to analyze the magnitude of the influence of obesity and T2DM on COVID-19 mortality. Subjects and Method: This study uses a systematic review and meta-analysis research design. The time of the selected test results is between January 2020 to January 2021. The search for articles is carried out for 1 month. Research data was searched from databases: PubMed, Google Scholar, JAMA, Willey, and Science Direct. Using search keywords: (Type 2 diabetes mellitus OR diabetic) AND (mortality OR death) AND (COVID-19 /OR Coronavirus OR SARS-CoV-2) AND (\"adjusted odds ratio\" OR \"aOR\"), (obesity OR obese) AND (mortality OR death) AND (COVID-19 OR Coronavirus OR SARS-CoV-2) AND (\"adjusted odds ratio\" OR \"aOR\"). The inclusion criteria in this study were full-text articles in English, observational study designs were collected using PRISMA, and analyzed using the Review Manager application (RevMan 5.3). Results: A total of 15 articles were reviewed in this study. A meta-analysis of 10 cohort studies showed that people with COVID19 who had comorbid obesity were 1.50 times more likely to die from COVID-19 compared to those without obesity (aOR = 1.50; 95% CI = 1.17 to 1.93; p = 0.001). A meta-analysis of 6 cohort studies showed people with COVID-1919 who had comorbid T2DM 1.93 times to die from COVID-19 compared with those without T2DM (aOR = 1.93; 95% CI = 1.28 to 2.90; p = 0.002). Conclusion: Obesity and T2DM are predictors of COVID19 mortality. Keywords: obesity, type 2 diabetes mellitus, mortality, COVID 19 Correspondence: Oktaviana Kurniawati. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: oktaniawati94@gmail.com. Mobile: 085865463742. Journal of Epidemiology and Public Health (2021), 06(02): 177-191 https://doi.org/10.26911/jepublichealth.2021.06.02.05","PeriodicalId":91740,"journal":{"name":"Journal of epidemiology and public health reviews","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90531096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-11DOI: 10.26911/jepublichealth.2021.06.01.08
Yuzana Maung, E. Pamungkasari, Bhisma Murti
Background : COVID-19, caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), emerged as a global pandemic with confirmed death cases of more than 1.27 million worldwide. Since the past pandemic, several studies discovered the adverse effects of excess fat accumulation on the severity of viral infections. This study aimed to investigate the association between high body mass index (BMI) and mortality risk in hospitalized COVID-19 patients based on four categories of high BMI ranges. Subjects and Method : A systematic review and Meta-Analysis was conducted using search articles from electronic databases including PubMed, Google Scholar, and Scopus, published from 2019 to 2021. The keywords used to retrieve articles were "Body Mass Index" OR BMI OR Obesity OR Overweight) AND (Mortality OR Death) AND COVID-19 OR SARS-CoV-2. The included studies were full-text articles published in the English language, reporting adjusted odds ratios from multivariate analysis. The eligibility criteria were defined using PICO model. The article selection was conducted using PRISMA flow chart. The included studies were analyzed by the Review Manager 5.3 application. Results : A total of nine cohort studies involving 12,907 COVID-19 patients with high BMI conducted from America, Europe, and Georgia regions was included in qualitative synthesis and Meta-Analysis. The pooled estimate showed hospitalized COVID-19 patients with morbid/ class III obesity had a higher risk of mortality (aOR= 1.77; 95% CI= 1.27 to 2.47; p= 0.001) than overweight (aOR= 1.10; 95% CI= 1.00 to 1.21; p= 0.060), class I (aOR= 1.16; 95% CI= 0.87 to 1.55; p= 0.300), and class II obesity (aOR= 1.54; 95% CI= 1.11 to 2.13; p= 0.009). Conclusion : High BMI increases the risk of mortality in hospitalized COVID-19 patients. A potential dose-response relationship may exist between different categories of high BMI range and mortality risk in COVID-19 patients. Keywords : BMI, obesity, mortality, COVID-19, SARS-CoV-2 Correspondence : Yuzana Maung. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: yuzmg5699@gmail.com. Mobile: +6281295346614. Journal of Epidemiology and Public Health (2021) https://doi.org/10.26911/jepublichealth.2021.06.01.08
{"title":"The Association between High Body Mass Index and Mortality Risk in Hospitalized Patients Diagnosed with COVID-19: A Meta-Analysis","authors":"Yuzana Maung, E. Pamungkasari, Bhisma Murti","doi":"10.26911/jepublichealth.2021.06.01.08","DOIUrl":"https://doi.org/10.26911/jepublichealth.2021.06.01.08","url":null,"abstract":"Background : COVID-19, caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), emerged as a global pandemic with confirmed death cases of more than 1.27 million worldwide. Since the past pandemic, several studies discovered the adverse effects of excess fat accumulation on the severity of viral infections. This study aimed to investigate the association between high body mass index (BMI) and mortality risk in hospitalized COVID-19 patients based on four categories of high BMI ranges. Subjects and Method : A systematic review and Meta-Analysis was conducted using search articles from electronic databases including PubMed, Google Scholar, and Scopus, published from 2019 to 2021. The keywords used to retrieve articles were \"Body Mass Index\" OR BMI OR Obesity OR Overweight) AND (Mortality OR Death) AND COVID-19 OR SARS-CoV-2. The included studies were full-text articles published in the English language, reporting adjusted odds ratios from multivariate analysis. The eligibility criteria were defined using PICO model. The article selection was conducted using PRISMA flow chart. The included studies were analyzed by the Review Manager 5.3 application. Results : A total of nine cohort studies involving 12,907 COVID-19 patients with high BMI conducted from America, Europe, and Georgia regions was included in qualitative synthesis and Meta-Analysis. The pooled estimate showed hospitalized COVID-19 patients with morbid/ class III obesity had a higher risk of mortality (aOR= 1.77; 95% CI= 1.27 to 2.47; p= 0.001) than overweight (aOR= 1.10; 95% CI= 1.00 to 1.21; p= 0.060), class I (aOR= 1.16; 95% CI= 0.87 to 1.55; p= 0.300), and class II obesity (aOR= 1.54; 95% CI= 1.11 to 2.13; p= 0.009). Conclusion : High BMI increases the risk of mortality in hospitalized COVID-19 patients. A potential dose-response relationship may exist between different categories of high BMI range and mortality risk in COVID-19 patients. Keywords : BMI, obesity, mortality, COVID-19, SARS-CoV-2 Correspondence : Yuzana Maung. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: yuzmg5699@gmail.com. Mobile: +6281295346614. Journal of Epidemiology and Public Health (2021) https://doi.org/10.26911/jepublichealth.2021.06.01.08","PeriodicalId":91740,"journal":{"name":"Journal of epidemiology and public health reviews","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78539537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-11DOI: 10.26911/jepublichealth.2021.06.01.07
Nanda Agustian Simatupang, V. Widyaningsih, S. Sumardiyono
Background: SARS-CoV-2 is a new type of coronavirus that has never been previously identified in humans. In severe cases of COVID-19 it can cause pneumonia, acute respiratory syndrome, kidney failure, and even death. Hypertension causes a number of pathophysiological changes in the cardiovascular system such as left ventricular hypertrophy and fibrosis. This can make a hypertensive heart particularly vulnerable to SARS-CoV-2. This study aims to analyze and estimate the effect of comorbid hypertension on mortality in COVID-19 patients. Subjects and Method: This was a systematic review and meta-analysis conducted with PRISMA flow diagram. Article searches through journal databases include: Google Scholar, PubMed, Science Direct, and Springer Link by selecting articles published in 2020 and 2021. The keywords used are “Hypertension” OR “Hypertensive Patient” OR “Blood Pressure”, “Systolic Pressure” OR “Diastolic Pressure” AND “Mortality”, OR “death” OR “loss” AND “COVID-19” OR “SARS-COV-2” OR “coronavirus” AND “multivariate”. The inclusion criteria were full paper articles with observational research methods, the results of the analysis used the aOR value, the exposure given was comorbid hypertension, the research subjects were COVID-19 patients, with mortality outcomes. Eligible articles were analyzed using the Revman 5.3 app. Results: A meta-analysis of 18 articles showed that confirmed COVID-19 patients who had comorbid hypertension had a 1.27 times risk of mortality compared to those without comorbid hypertension and were statistically significant (aOR= 1.27; 95% CI= 1.14 to 1.41; p <0.001). Conclusion: Comorbid Hypertension affects the mortality of COVID-19 patients. Keywords: hypertension, mortality, COVID-19, meta-analysis Correspondence: Nanda Agustian Simatupang. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: nandaagustian9@gmail.com. Mobile: 082247604322. Journal of Epidemiology and Public Health (2021), 06(01) https://doi.org/10.26911/jepublichealth.2021.06.01.07
{"title":"A Meta-Analysis: Correlation between Hypertension of Comorbidity on Mortality in Patients with COVID-19","authors":"Nanda Agustian Simatupang, V. Widyaningsih, S. Sumardiyono","doi":"10.26911/jepublichealth.2021.06.01.07","DOIUrl":"https://doi.org/10.26911/jepublichealth.2021.06.01.07","url":null,"abstract":"Background: SARS-CoV-2 is a new type of coronavirus that has never been previously identified in humans. In severe cases of COVID-19 it can cause pneumonia, acute respiratory syndrome, kidney failure, and even death. Hypertension causes a number of pathophysiological changes in the cardiovascular system such as left ventricular hypertrophy and fibrosis. This can make a hypertensive heart particularly vulnerable to SARS-CoV-2. This study aims to analyze and estimate the effect of comorbid hypertension on mortality in COVID-19 patients. Subjects and Method: This was a systematic review and meta-analysis conducted with PRISMA flow diagram. Article searches through journal databases include: Google Scholar, PubMed, Science Direct, and Springer Link by selecting articles published in 2020 and 2021. The keywords used are “Hypertension” OR “Hypertensive Patient” OR “Blood Pressure”, “Systolic Pressure” OR “Diastolic Pressure” AND “Mortality”, OR “death” OR “loss” AND “COVID-19” OR “SARS-COV-2” OR “coronavirus” AND “multivariate”. The inclusion criteria were full paper articles with observational research methods, the results of the analysis used the aOR value, the exposure given was comorbid hypertension, the research subjects were COVID-19 patients, with mortality outcomes. Eligible articles were analyzed using the Revman 5.3 app. Results: A meta-analysis of 18 articles showed that confirmed COVID-19 patients who had comorbid hypertension had a 1.27 times risk of mortality compared to those without comorbid hypertension and were statistically significant (aOR= 1.27; 95% CI= 1.14 to 1.41; p <0.001). Conclusion: Comorbid Hypertension affects the mortality of COVID-19 patients. Keywords: hypertension, mortality, COVID-19, meta-analysis Correspondence: Nanda Agustian Simatupang. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: nandaagustian9@gmail.com. Mobile: 082247604322. Journal of Epidemiology and Public Health (2021), 06(01) https://doi.org/10.26911/jepublichealth.2021.06.01.07","PeriodicalId":91740,"journal":{"name":"Journal of epidemiology and public health reviews","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85850087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-11DOI: 10.26911/jepublichealth.2021.06.01.02
Frenky Sorimuda Manullang, Adlin Adnan, D. Munir
Background: Presbycusis incidence is thought to have a relationship with hereditary factors, metabolism, atherosclerosis, noise and lifestyle. The presbycusis classification consists of Sensory (outer hair-cell), neural (ganglion-cell), metabolic (strial atrophy), and conductive cochlea (stiffness of the basilar membrane). Factors that influence presbycusis include age, gender, genetics, hypertension, gout, diabetes mellitus, hypercholesterolemia, noise exposure, and smoking. This study aims to determine the factors that influence presbycusis on the audiogram image at H. Adam Malik Hospital Medan. Subjects and Method: This study was an analytical study with a cross sectional design in elderly patients at the polyclinic. The study was conducted in November to December 2019. The dependent variable was the incidence of presbycusis. The independent variables were uric acid levels, blood sugar levels, smoking habits, hypercholesterolemia, and hypertension. Data were analyzed by using chi square test. Results: The prevalence of presbycusis in the 45-59 years age group was 39 people (54.2%) and the 60-74 years age group was 33 people (45.8%). In this study, it shows that male respondents are more than female respondents, where the number of men is 58 people (80.6%) and women are 14 people (19.4%). Based on presbycusis type, there were 33 (45.9%) people (normal), 18 (25%) people (strrial type), 7 (7.9%) people (neural type), 7 (7.9%) people (sensory type), 7 (7.9%) people (cochlear type). High sugar content (OR= 3.33; 95% CI= 1.81 to 6.13; p <0.001), uric acid levels (OR= 2.36; 95% CI= 1.19 to 4.70; p= 0.005), total cholesterol levels (OR= 3.33; 95% CI= 1.81 to 6.13; p <0.001), and smoking (OR= 1.90; 95% CI = 1.21 to 2.97; p= 0.016) increased the risk of presbycusis. Conclusion: High sugar levels, uric acid levels, total cholesterol levels, and smoking habits increase the risk of presbycusis. Keywords: presbycusis, audiogram image Correspondence: Frenky Sorimuda Manullang. Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia. Email: manulangdrfrenky@gmail.com. Mobile: +62-8126394830. Journal of Epidemiology and Public Health (2021), 06(01): 12-20 https://doi.org/10.26911/jepublichealth.2021.06.01.02
{"title":"Factors Affecting Presbycusis on Audiogram Overview at H. Adam Malik General Hospital Medan","authors":"Frenky Sorimuda Manullang, Adlin Adnan, D. Munir","doi":"10.26911/jepublichealth.2021.06.01.02","DOIUrl":"https://doi.org/10.26911/jepublichealth.2021.06.01.02","url":null,"abstract":"Background: Presbycusis incidence is thought to have a relationship with hereditary factors, metabolism, atherosclerosis, noise and lifestyle. The presbycusis classification consists of Sensory (outer hair-cell), neural (ganglion-cell), metabolic (strial atrophy), and conductive cochlea (stiffness of the basilar membrane). Factors that influence presbycusis include age, gender, genetics, hypertension, gout, diabetes mellitus, hypercholesterolemia, noise exposure, and smoking. This study aims to determine the factors that influence presbycusis on the audiogram image at H. Adam Malik Hospital Medan. Subjects and Method: This study was an analytical study with a cross sectional design in elderly patients at the polyclinic. The study was conducted in November to December 2019. The dependent variable was the incidence of presbycusis. The independent variables were uric acid levels, blood sugar levels, smoking habits, hypercholesterolemia, and hypertension. Data were analyzed by using chi square test. Results: The prevalence of presbycusis in the 45-59 years age group was 39 people (54.2%) and the 60-74 years age group was 33 people (45.8%). In this study, it shows that male respondents are more than female respondents, where the number of men is 58 people (80.6%) and women are 14 people (19.4%). Based on presbycusis type, there were 33 (45.9%) people (normal), 18 (25%) people (strrial type), 7 (7.9%) people (neural type), 7 (7.9%) people (sensory type), 7 (7.9%) people (cochlear type). High sugar content (OR= 3.33; 95% CI= 1.81 to 6.13; p <0.001), uric acid levels (OR= 2.36; 95% CI= 1.19 to 4.70; p= 0.005), total cholesterol levels (OR= 3.33; 95% CI= 1.81 to 6.13; p <0.001), and smoking (OR= 1.90; 95% CI = 1.21 to 2.97; p= 0.016) increased the risk of presbycusis. Conclusion: High sugar levels, uric acid levels, total cholesterol levels, and smoking habits increase the risk of presbycusis. Keywords: presbycusis, audiogram image Correspondence: Frenky Sorimuda Manullang. Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia. Email: manulangdrfrenky@gmail.com. Mobile: +62-8126394830. Journal of Epidemiology and Public Health (2021), 06(01): 12-20 https://doi.org/10.26911/jepublichealth.2021.06.01.02","PeriodicalId":91740,"journal":{"name":"Journal of epidemiology and public health reviews","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80512674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-11DOI: 10.26911/jepublichealth.2021.06.01.12
Faricha Indra Hapsari, S. Rahardjo, Hanung Prasetya
Background: Acupuncture is a traditional Chinese medicine for treating ailments, including diseases of the cardiovascular system, such as hypertension. Acupuncture modulates neurohumoral regulatory systems and cardiovascular function. This study aims to estimate the effectiveness of acupuncture therapy in reducing blood pressure in hypertensive patients. Subjects and Method: This was a systematic review and meta-analysis, with PICO, namely Population= hypertension cases aged 20-80 years. Intervention= acupuncture therapy. Comparison= Sham/ Placebo/ No Treatment Acupuncture. Outcome = Blood pressure. The articles used in this study were obtained from several databases including Google Scholar, MEDLINE/ PubMed, Science Direct, Hindawi, BMC, Europe PMC and Springer Link. These articles were collected for 1 month. The keywords to search for articles were as follows: “acupuncture”, “hypertension”, “randomized controlled trial”, “hypertension randomized controlled trial”, “acupuncture randomized controlled trial”, “acupuncture for primary hypertension”, “acupuncture for hypertension essential” AND “acupuncture for blood pressure”. The articles included in this study are full text articles with a randomized controlled trial study design. Articles were collected using PRISMA flow diagrams and analyzed using the Review Manager application (RevMan) 5.3. Results: A total of 9 articles were reviewed in this meta-analysis. Articles are from America, Germany, Korea, China, India and Taiwan. The study showed that acupuncture therapy was able to reduce systolic blood pressure with the Standardized Mean Different by 0.54 compared to sham acupuncture /placebo/no treatment (SMD= 0.54; 95% CI= -1.04 to -0.04; p 0.05) compared to sham acupuncture/ placebo, but it was statistically non significant. Conclusion: Acupuncture can reduce systolic blood pressure, but it is less significant in reducing diastolic blood pressure in hypertensive patients. Keywords: acupuncture, hypertension, high blood pressure. Correspondence: Faricha Indra Hapsari. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta57126, Central Java. Email: farichaindrah@gmail.com Mobile: +6285647075776 Journal of Epidemiology and Public Health (2021), 06(01): 125-133 https://doi.org/10.26911/jepublichealth.2021.06.01.12
{"title":"The Effect of Acupuncture Therapy on Reducing Blood Pressure in Hypertension Patients: Meta-Analysis","authors":"Faricha Indra Hapsari, S. Rahardjo, Hanung Prasetya","doi":"10.26911/jepublichealth.2021.06.01.12","DOIUrl":"https://doi.org/10.26911/jepublichealth.2021.06.01.12","url":null,"abstract":"Background: Acupuncture is a traditional Chinese medicine for treating ailments, including diseases of the cardiovascular system, such as hypertension. Acupuncture modulates neurohumoral regulatory systems and cardiovascular function. This study aims to estimate the effectiveness of acupuncture therapy in reducing blood pressure in hypertensive patients. Subjects and Method: This was a systematic review and meta-analysis, with PICO, namely Population= hypertension cases aged 20-80 years. Intervention= acupuncture therapy. Comparison= Sham/ Placebo/ No Treatment Acupuncture. Outcome = Blood pressure. The articles used in this study were obtained from several databases including Google Scholar, MEDLINE/ PubMed, Science Direct, Hindawi, BMC, Europe PMC and Springer Link. These articles were collected for 1 month. The keywords to search for articles were as follows: “acupuncture”, “hypertension”, “randomized controlled trial”, “hypertension randomized controlled trial”, “acupuncture randomized controlled trial”, “acupuncture for primary hypertension”, “acupuncture for hypertension essential” AND “acupuncture for blood pressure”. The articles included in this study are full text articles with a randomized controlled trial study design. Articles were collected using PRISMA flow diagrams and analyzed using the Review Manager application (RevMan) 5.3. Results: A total of 9 articles were reviewed in this meta-analysis. Articles are from America, Germany, Korea, China, India and Taiwan. The study showed that acupuncture therapy was able to reduce systolic blood pressure with the Standardized Mean Different by 0.54 compared to sham acupuncture /placebo/no treatment (SMD= 0.54; 95% CI= -1.04 to -0.04; p 0.05) compared to sham acupuncture/ placebo, but it was statistically non significant. Conclusion: Acupuncture can reduce systolic blood pressure, but it is less significant in reducing diastolic blood pressure in hypertensive patients. Keywords: acupuncture, hypertension, high blood pressure. Correspondence: Faricha Indra Hapsari. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta57126, Central Java. Email: farichaindrah@gmail.com Mobile: +6285647075776 Journal of Epidemiology and Public Health (2021), 06(01): 125-133 https://doi.org/10.26911/jepublichealth.2021.06.01.12","PeriodicalId":91740,"journal":{"name":"Journal of epidemiology and public health reviews","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73898313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-11DOI: 10.26911/jepublichealth.2021.06.01.10
Annissa Devi Permata, Bhisma Murti, D. Tamtomo
Background: Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-2). SARS-CoV-2 is a new type of coronavirus that has never been previously identified in humans. Globally, 213 countries (as of August 11, 2020) are facing serious consequences from the ongoing COVID-19 pandemic. This study aimed to analyze the magnitude of the relationship of hypertension, gender, and older age to COVID-19 mortality with a meta-analysis study. Subjects and Method: This was a systematic review and meta-analysis conducted by following the PRISMA flow diagram. The article search process is carried out through a journal database which includes: PubMed, Science Direct, Springer Link, and PMC Europe by selecting articles published in 2020-2021. The keywords used included: “sex” OR “gender” AND “older age” AND “hypertension” AND “mortality” OR “death” OR “fatal outcome” OR “Predictors outcome” OR “Impact” AND “coronavirus” OR “Covid-19” OR “SARS-COV-2” OR “2019 n-Cov” OR “severe acute respiratory syndrome related coronavirus”. The inclusion criteria were full text articles with a retrospective cohort study design. The article is in English, and the analysis used is multivariate with adjusted Odds Ratio. Eligible articles were analyzed using the Revman 5.3 app. Results: A total of 20 articles were reviewed in this study. A meta-analysis of 10 retrospective cohort studies showed that hypertension increased COVID-19 mortality by 1.40 times compared with no hypertension (aOR= 1.40; 95% CI= 1.04 to 1.89; p = 0.030). A meta-analysis of 10 retrospective cohort studies showed that males had a 1.42 times increased risk of COVID-19 mortality compared to females (aOR= 1.42; 95% CI= 1.20 to 1.67; p<0.001). Meta-analysis of 7 retrospective cohort studies showed that old age has a 3.42 times increased risk of COVID-19 death compared to younger age (aOR=4.15; 95% CI= 2.35 to 7.32; p <0.001). Conclusion: Hypertension, gender, and old age increase the risk of dying from COVID-19. Keywords: Hypertension, Gender, Old Age, COVID-19 Death, Meta-analysis Correspondence: Annissa Devi Permata. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami, 36A, Surakarta 57126, Central Java, Indonesia. Email: 96annissadevipermata@gmail.com Journal of Epidemiology and Public Health (2021), 06(01): 98-111 https://doi.org/10.26911/jepublichealth.2021.06.01.10
{"title":"Hypertension, Gender, Older Age, and Their Relationships with COVID-19 Mortality: Meta-Analysis","authors":"Annissa Devi Permata, Bhisma Murti, D. Tamtomo","doi":"10.26911/jepublichealth.2021.06.01.10","DOIUrl":"https://doi.org/10.26911/jepublichealth.2021.06.01.10","url":null,"abstract":"Background: Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-2). SARS-CoV-2 is a new type of coronavirus that has never been previously identified in humans. Globally, 213 countries (as of August 11, 2020) are facing serious consequences from the ongoing COVID-19 pandemic. This study aimed to analyze the magnitude of the relationship of hypertension, gender, and older age to COVID-19 mortality with a meta-analysis study. Subjects and Method: This was a systematic review and meta-analysis conducted by following the PRISMA flow diagram. The article search process is carried out through a journal database which includes: PubMed, Science Direct, Springer Link, and PMC Europe by selecting articles published in 2020-2021. The keywords used included: “sex” OR “gender” AND “older age” AND “hypertension” AND “mortality” OR “death” OR “fatal outcome” OR “Predictors outcome” OR “Impact” AND “coronavirus” OR “Covid-19” OR “SARS-COV-2” OR “2019 n-Cov” OR “severe acute respiratory syndrome related coronavirus”. The inclusion criteria were full text articles with a retrospective cohort study design. The article is in English, and the analysis used is multivariate with adjusted Odds Ratio. Eligible articles were analyzed using the Revman 5.3 app. Results: A total of 20 articles were reviewed in this study. A meta-analysis of 10 retrospective cohort studies showed that hypertension increased COVID-19 mortality by 1.40 times compared with no hypertension (aOR= 1.40; 95% CI= 1.04 to 1.89; p = 0.030). A meta-analysis of 10 retrospective cohort studies showed that males had a 1.42 times increased risk of COVID-19 mortality compared to females (aOR= 1.42; 95% CI= 1.20 to 1.67; p<0.001). Meta-analysis of 7 retrospective cohort studies showed that old age has a 3.42 times increased risk of COVID-19 death compared to younger age (aOR=4.15; 95% CI= 2.35 to 7.32; p <0.001). Conclusion: Hypertension, gender, and old age increase the risk of dying from COVID-19. Keywords: Hypertension, Gender, Old Age, COVID-19 Death, Meta-analysis Correspondence: Annissa Devi Permata. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami, 36A, Surakarta 57126, Central Java, Indonesia. Email: 96annissadevipermata@gmail.com Journal of Epidemiology and Public Health (2021), 06(01): 98-111 https://doi.org/10.26911/jepublichealth.2021.06.01.10","PeriodicalId":91740,"journal":{"name":"Journal of epidemiology and public health reviews","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88442482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-11DOI: 10.26911/jepublichealth.2021.06.01.09
Glory Okwori
Background: Adverse childhood experiences (ACEs) are associated with negative outcomes, however, there are factors that can mitigate the effects from exposure to ACEs. This study examined the prevalence of adverse childhood experiences (ACEs), characteristics of resilient individuals and the association between ACE scores, resiliency and other factors among college students. Subjects and Method: A cross-sectional survey was completed in 2018. Frequencies were calculated for the number and types of ACE experienced by participants. Bivariate relationships between characteristics of participants and resilience were examined using Chi-square tests. The independent relationship between ACE scores and resiliency factors was examined using ordinal logistic regression. The dependent variable was ACE score. An ordinal logistic regression model examined the relationship between conventional ACE scores and resilience levels and other factors. Results: There were 570 study participants. Seventy-one percent of study participants had experienced at least one conventional ACE, and 98% had experienced at least one expanded ACE. Individuals with high resilience had lower conventional ACE scores and better health. Females (OR= 1.67; 95% CI= 1.14 to 2.45) were more likely to have higher conventional ACE scores. Participants living in suburban areas compared to rural areas (OR= 0.61; 95% CI: 0.43 to 0.85), and children raised with both parents compared to single parents (OR= 0.17; 95% CI= 0.12 to 0.25) were less likely to have higher conventional ACE scores. Gender (OR= 0.54; 95% CI= 0.35 to 0.82) and general health status (OR= 1.50; 95% CI= 1.05 to 2.13) were the only significant predictors of the expanded ACE scores. Conclusion: Findings identify important resilient traits such as relationships, self-control, internal beliefs, and initiative,. as well asportray the high prevalence ofACEs and the importance of resilience as a protective factor in reducing ACEs. Keywords: adverse childhood experiences, resilience, mitigate Correspondence : Glory Okwori. East Tennessee State University. 1276 Gilbreath Dr., Box 70300, Johnson City, TN. Email: okwori@etsu.edu. Journal of Epidemiology and Public Health (2021), 06(01): 83-97 https://doi.org/10.26911/jepublichealth.2021.06.01.09
{"title":"Relationship between Adverse Childhood Experiences and Resiliency among College Students","authors":"Glory Okwori","doi":"10.26911/jepublichealth.2021.06.01.09","DOIUrl":"https://doi.org/10.26911/jepublichealth.2021.06.01.09","url":null,"abstract":"Background: Adverse childhood experiences (ACEs) are associated with negative outcomes, however, there are factors that can mitigate the effects from exposure to ACEs. This study examined the prevalence of adverse childhood experiences (ACEs), characteristics of resilient individuals and the association between ACE scores, resiliency and other factors among college students. Subjects and Method: A cross-sectional survey was completed in 2018. Frequencies were calculated for the number and types of ACE experienced by participants. Bivariate relationships between characteristics of participants and resilience were examined using Chi-square tests. The independent relationship between ACE scores and resiliency factors was examined using ordinal logistic regression. The dependent variable was ACE score. An ordinal logistic regression model examined the relationship between conventional ACE scores and resilience levels and other factors. Results: There were 570 study participants. Seventy-one percent of study participants had experienced at least one conventional ACE, and 98% had experienced at least one expanded ACE. Individuals with high resilience had lower conventional ACE scores and better health. Females (OR= 1.67; 95% CI= 1.14 to 2.45) were more likely to have higher conventional ACE scores. Participants living in suburban areas compared to rural areas (OR= 0.61; 95% CI: 0.43 to 0.85), and children raised with both parents compared to single parents (OR= 0.17; 95% CI= 0.12 to 0.25) were less likely to have higher conventional ACE scores. Gender (OR= 0.54; 95% CI= 0.35 to 0.82) and general health status (OR= 1.50; 95% CI= 1.05 to 2.13) were the only significant predictors of the expanded ACE scores. Conclusion: Findings identify important resilient traits such as relationships, self-control, internal beliefs, and initiative,. as well asportray the high prevalence ofACEs and the importance of resilience as a protective factor in reducing ACEs. Keywords: adverse childhood experiences, resilience, mitigate Correspondence : Glory Okwori. East Tennessee State University. 1276 Gilbreath Dr., Box 70300, Johnson City, TN. Email: okwori@etsu.edu. Journal of Epidemiology and Public Health (2021), 06(01): 83-97 https://doi.org/10.26911/jepublichealth.2021.06.01.09","PeriodicalId":91740,"journal":{"name":"Journal of epidemiology and public health reviews","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75054973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-11DOI: 10.26911/jepublichealth.2021.06.01.01
Mutiana Agustin Sholikah, Agus Kristiyanto, Hanung Prasetya
Background: Children with cerebral palsy generally experience hand functional disorders which then affect the child's occupational performance. Hand functional ability is the ability to use the hand in doing activities. To be able to perform occupational performance, good hand functional abilities are needed. To achieve this, interventions are needed, one of which is constraint-induced movement therapy (CIMT) which is hypothesized to be able to improve hand functional ability and occupational per-formance. The purpose of this study was to determine the effect of CIMT on the hands functional ability and the occupation performance of children with cerebral palsy. Subjects and Method: This study used a systematic review design and meta-analysis using the PRISMA flow chart guidelines. The process of searching for articles was carried out between 2005-2020 using databases from PubMed, Science Direct, AJOT, Springer Link, and Google Scholar. Based on the database, there were 20 articles that met the inclusion criteria. This study involved 669 subjects of hand functional ability and 440 subjects of occupational performance. The analysis was performed using the RevMan 5.3 software. Results: A total of 20 articles conducted a meta-analysis review. A total of 18 articles conducted a meta-analysis showing that giving CIMT to children with cerebral palsy was significantly able to improve hands functional ability of children with cerebral palsy (SMD = 0.40; 95% CI 0.09 to 0.71; p = 0.01). A total of 11 articles conducted a meta-analysis showing that giving CIMT to children with cerebral palsy was able to improve occupational performance abilities but it was not statistically significant (SMD = 0.18; 95% CI 0.17 to 0.52; p = 0.32). Conclusion: CIMT can improve hand functional abilities and occupational performance of children with cerebral palsy. Keywords: constraint-induced movement therapy (CIMT), hand functional ability, occupational performance, cerebral palsy, meta-analysis Correspondence: Mutiana Agustin Sholikah. Masters Program in Public Health. Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Jawa Tengah, Indonesia. Email: mutiana.ash@gmail.com. Mobile: 081215038686. Journal of Epidemiology and Public Health (2021), 06(01): 1-11 https://doi.org/10.26911/jepublichealth.2021.06.01.01
{"title":"Meta-Analysis the Effect of Constraint-Induced Movement Therapy on Hands Functional Ability and Occupational Performance in Children with Cerebral Palsy","authors":"Mutiana Agustin Sholikah, Agus Kristiyanto, Hanung Prasetya","doi":"10.26911/jepublichealth.2021.06.01.01","DOIUrl":"https://doi.org/10.26911/jepublichealth.2021.06.01.01","url":null,"abstract":"Background: Children with cerebral palsy generally experience hand functional disorders which then affect the child's occupational performance. Hand functional ability is the ability to use the hand in doing activities. To be able to perform occupational performance, good hand functional abilities are needed. To achieve this, interventions are needed, one of which is constraint-induced movement therapy (CIMT) which is hypothesized to be able to improve hand functional ability and occupational per-formance. The purpose of this study was to determine the effect of CIMT on the hands functional ability and the occupation performance of children with cerebral palsy. Subjects and Method: This study used a systematic review design and meta-analysis using the PRISMA flow chart guidelines. The process of searching for articles was carried out between 2005-2020 using databases from PubMed, Science Direct, AJOT, Springer Link, and Google Scholar. Based on the database, there were 20 articles that met the inclusion criteria. This study involved 669 subjects of hand functional ability and 440 subjects of occupational performance. The analysis was performed using the RevMan 5.3 software. Results: A total of 20 articles conducted a meta-analysis review. A total of 18 articles conducted a meta-analysis showing that giving CIMT to children with cerebral palsy was significantly able to improve hands functional ability of children with cerebral palsy (SMD = 0.40; 95% CI 0.09 to 0.71; p = 0.01). A total of 11 articles conducted a meta-analysis showing that giving CIMT to children with cerebral palsy was able to improve occupational performance abilities but it was not statistically significant (SMD = 0.18; 95% CI 0.17 to 0.52; p = 0.32). Conclusion: CIMT can improve hand functional abilities and occupational performance of children with cerebral palsy. Keywords: constraint-induced movement therapy (CIMT), hand functional ability, occupational performance, cerebral palsy, meta-analysis Correspondence: Mutiana Agustin Sholikah. Masters Program in Public Health. Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Jawa Tengah, Indonesia. Email: mutiana.ash@gmail.com. Mobile: 081215038686. Journal of Epidemiology and Public Health (2021), 06(01): 1-11 https://doi.org/10.26911/jepublichealth.2021.06.01.01","PeriodicalId":91740,"journal":{"name":"Journal of epidemiology and public health reviews","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88972626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-11DOI: 10.26911/jepublichealth.2021.06.01.03
Lina Eta Safitri, Agus Kristiyanto, Bhisma Murti
Background: About 23% of the world's population smokes, which includes 32% of men with the highest prevalence coming from Indonesia and 7% are women. East Asia and Southeast Asia have the highest smoking prevalence in the world at around 45%, while in Indonesia, the problem of smoking is a serious threat due to the increasing prevalence of smoking at 18 years of age from 7.2% to 9.1%. This study aims to analyze the magnitude of the effect of using NRT on the success of smoking cessation based on a number of previous similar studies. Subjects and Method: This research is a systematic review and meta-analysis carried out by following the PRISMA flow diagram. The process of searching for articles through a journal database which includes: Google Scholar, PubMed, and Science Direct by selecting articles published in 2011-2020. Keywords used include: "nicotine replacement therapy" AND "smoker" OR "smoking" AND "smoking cessation". The inclusion criteria were a full paper article with an observational study design, English and Indonesian, and analyzed using multivariate analysis with adjusted odds ratio. Articles that meet the requirements were analyzed using the Revman 5.3 application. Results: Nine articles were reviewed in this study with a cohort study design. A meta-analysis of nine cohort studies showed that use of nicotine replacement therapy was 1.42 fold increased smoking cessation success compared to placebo (aOR 1.42; 95% CI 1.14 to 1.76; p <0.002). Conclusion: Nicotine replacement therapy improves smoking cessation success. Keyword s : nicotine replacement therapy, smoking cessation Correspondence: Lina Eta Safitri. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: Linaetasafitri_96@student.uns.ac.id Journal of Epidemiology and Public Health (2021), 06(01): 21-32 https://doi.org/10.26911/jepublichealth.2021.06.01.03
背景:世界上约有23%的人口吸烟，其中32%的男性吸烟，其中印度尼西亚的吸烟率最高，7%为女性。东亚和东南亚的吸烟率在世界上最高，约为45%，而在印度尼西亚，吸烟问题是一个严重的威胁，因为18岁的吸烟率从7.2%上升到9.1%。本研究旨在基于之前的一些类似研究，分析使用NRT对戒烟成功的影响程度。研究对象和方法:本研究采用PRISMA流程图进行系统综述和meta分析。通过期刊数据库搜索文章的过程，包括:Google Scholar, PubMed和Science Direct，通过选择2011-2020年发表的文章。使用的关键词包括:“尼古丁替代疗法”和“吸烟者”或“吸烟”和“戒烟”。纳入标准为一篇观察性研究设计的完整论文，英文和印尼语，采用校正优势比的多变量分析。使用Revman 5.3应用程序对满足需求的文章进行了分析。结果:本研究采用队列研究设计，回顾了9篇文献。一项对9项队列研究的荟萃分析显示，与安慰剂相比，尼古丁替代疗法的戒烟成功率提高了1.42倍(aOR 1.42;95% CI 1.14 ~ 1.76;p < 0.002)。结论:尼古丁替代疗法可提高戒烟成功率。关键词:尼古丁替代疗法，戒烟通讯，Lina Eta Safitri。公共卫生硕士课程，西贝拉斯市场大学，jr。红外光谱。Sutami 36A, Surakarta 57126，中爪哇。电子邮件:Linaetasafitri_96@student.uns.ac.id流行病学与公共卫生杂志(2021)，06(01):21-32 https://doi.org/10.26911/jepublichealth.2021.06.01.03
{"title":"Meta-Analysis the Effect of Nicotine Replacement Therapy on the Successful Smoking Cessation","authors":"Lina Eta Safitri, Agus Kristiyanto, Bhisma Murti","doi":"10.26911/jepublichealth.2021.06.01.03","DOIUrl":"https://doi.org/10.26911/jepublichealth.2021.06.01.03","url":null,"abstract":"Background: About 23% of the world's population smokes, which includes 32% of men with the highest prevalence coming from Indonesia and 7% are women. East Asia and Southeast Asia have the highest smoking prevalence in the world at around 45%, while in Indonesia, the problem of smoking is a serious threat due to the increasing prevalence of smoking at 18 years of age from 7.2% to 9.1%. This study aims to analyze the magnitude of the effect of using NRT on the success of smoking cessation based on a number of previous similar studies. Subjects and Method: This research is a systematic review and meta-analysis carried out by following the PRISMA flow diagram. The process of searching for articles through a journal database which includes: Google Scholar, PubMed, and Science Direct by selecting articles published in 2011-2020. Keywords used include: \"nicotine replacement therapy\" AND \"smoker\" OR \"smoking\" AND \"smoking cessation\". The inclusion criteria were a full paper article with an observational study design, English and Indonesian, and analyzed using multivariate analysis with adjusted odds ratio. Articles that meet the requirements were analyzed using the Revman 5.3 application. Results: Nine articles were reviewed in this study with a cohort study design. A meta-analysis of nine cohort studies showed that use of nicotine replacement therapy was 1.42 fold increased smoking cessation success compared to placebo (aOR 1.42; 95% CI 1.14 to 1.76; p <0.002). Conclusion: Nicotine replacement therapy improves smoking cessation success. Keyword s : nicotine replacement therapy, smoking cessation Correspondence: Lina Eta Safitri. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: Linaetasafitri_96@student.uns.ac.id Journal of Epidemiology and Public Health (2021), 06(01): 21-32 https://doi.org/10.26911/jepublichealth.2021.06.01.03","PeriodicalId":91740,"journal":{"name":"Journal of epidemiology and public health reviews","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87769744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-11DOI: 10.26911/jepublichealth.2021.06.01.11
Mustainu Habibi, S. Rahardjo, Bhisma Murti
Background: Antiretroviral therapy (ART) has been successful in increasing the life span and quality of life of people living with HIV. The success of antiretroviral treatment can be assessed from the patient's compliance in taking the drugs prescribed by the doctor at the right time and at the right dose. Disclosure of HIV status and social support are factors associated with adherence to antiretroviral therapy (ART). This study aims to estimate the magnitude of disclosure of HIV status and social support with antiretroviral therapy adherence to adult patients with HIV/AIDS with a meta-analysis study. Subjects and Method: This was a systematic review and meta-analysis conducted using PRISMA flow diagrams. Article searches were conducted through journal databases including: Google Scholar, PubMed, Springer Link, Clinical key and ProQuest. The articles used in this study are articles that have been published from 2010-2021. The keywords to search for articles are as follows: "disclosing HIV and antiretroviral adherence", "Social Support or family support and antiretroviral adherence". The inclusion criteria were full text with cross-sectional study design, articles in English, multivariate analysis with adjusted odds ratio. Eligible articles were analyzed using the Revman 5.4 application. Results: A meta-analysis of 9 observational studies showed that patients who disclosed their HIV status increased adherence to antiretroviral therapy 2.3 times compared to patients who did not disclose significantly (aOR= 2.36 95% CI= 1.75 to 3.19; p< 0.001). A meta-analysis of 9 observational studies showed that patients who received social support significantly increased adherence to antiretroviral therapy 1.4 times compared to patients who did not have support (aOR= 1.46; 95% CI= 1.08 to 1.97; p= 0.010). Conclusion: Disclosure of HIV status and social support improves adherence to antiretroviral therapy in adult patients with HIV/AIDS. Keywords: Adherence, Antiretroviral therapy, HIV/AIDS, Disclosure of HIV status, Social support, Meta-analysis Correspondence: Musta’inul Habibi. Masters Program in Public Health. Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Central Java. Email: Mustainul87@gmail.com. Mobile: 085649959811. Journal of Epidemiology and Public Health (2021), 06(01): 112-124 h ttps://doi.org/10.26911/jepublichealth.2021.06.01.11
{"title":"Associations between HIV Status Disclosure, Social Support, and Adherence to and Antiretroviral Therapy in Adults Patients with HIV/AIDS","authors":"Mustainu Habibi, S. Rahardjo, Bhisma Murti","doi":"10.26911/jepublichealth.2021.06.01.11","DOIUrl":"https://doi.org/10.26911/jepublichealth.2021.06.01.11","url":null,"abstract":"Background: Antiretroviral therapy (ART) has been successful in increasing the life span and quality of life of people living with HIV. The success of antiretroviral treatment can be assessed from the patient's compliance in taking the drugs prescribed by the doctor at the right time and at the right dose. Disclosure of HIV status and social support are factors associated with adherence to antiretroviral therapy (ART). This study aims to estimate the magnitude of disclosure of HIV status and social support with antiretroviral therapy adherence to adult patients with HIV/AIDS with a meta-analysis study. Subjects and Method: This was a systematic review and meta-analysis conducted using PRISMA flow diagrams. Article searches were conducted through journal databases including: Google Scholar, PubMed, Springer Link, Clinical key and ProQuest. The articles used in this study are articles that have been published from 2010-2021. The keywords to search for articles are as follows: \"disclosing HIV and antiretroviral adherence\", \"Social Support or family support and antiretroviral adherence\". The inclusion criteria were full text with cross-sectional study design, articles in English, multivariate analysis with adjusted odds ratio. Eligible articles were analyzed using the Revman 5.4 application. Results: A meta-analysis of 9 observational studies showed that patients who disclosed their HIV status increased adherence to antiretroviral therapy 2.3 times compared to patients who did not disclose significantly (aOR= 2.36 95% CI= 1.75 to 3.19; p< 0.001). A meta-analysis of 9 observational studies showed that patients who received social support significantly increased adherence to antiretroviral therapy 1.4 times compared to patients who did not have support (aOR= 1.46; 95% CI= 1.08 to 1.97; p= 0.010). Conclusion: Disclosure of HIV status and social support improves adherence to antiretroviral therapy in adult patients with HIV/AIDS. Keywords: Adherence, Antiretroviral therapy, HIV/AIDS, Disclosure of HIV status, Social support, Meta-analysis Correspondence: Musta’inul Habibi. Masters Program in Public Health. Universitas Sebelas Maret, Jl.Ir. Sutami 36A, Surakarta 57126, Central Java. Email: Mustainul87@gmail.com. Mobile: 085649959811. Journal of Epidemiology and Public Health (2021), 06(01): 112-124 h ttps://doi.org/10.26911/jepublichealth.2021.06.01.11","PeriodicalId":91740,"journal":{"name":"Journal of epidemiology and public health reviews","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78987832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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