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Referrals for frenotomy/frenectomy between 2017-2022 to public dental services in Ribeirão Preto, Brazil. 2017-2022年期间,巴西里贝赫<e:1>普雷图的公共牙科服务部门推荐的截骨术/系带切除术。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-10 eCollection Date: 2025-01-01 DOI: 10.1590/1807-3107bor-2025.vol39.101
Larissa Dias Vilela, Ricardo Barbosa Lima, Angélica Aparecida de Oliveira, Aluísio Eustáquio de Freitas Miranda Filho, Soraya Fernandes Mestriner, Lea Assed Bezerra Silva, Katharina Morant Holanda de Oliveira Vanderlei, Raquel Assed Bezerra da Silva

In this study, referrals for lingual frenotomy/frenectomy (F/F) were evaluated in children younger than 7 years the public dental services of Ribeirão Preto, São Paulo, Brazil, from 2017 to 2022. In this longitudinal observational retrospective study, the Hygiaweb System (Power BI) platform to access electronic medical records, and the following variables were collected: incidence of F/F, reports of symptoms associated with ankyloglossia, duration of exclusive breastfeeding (EBF), professional categories requesting the referral, and multiprofessional evaluation. Descriptive analyses, associations between variables, comparisons between groups and incidence ratios were performed. The significance level was set at 5%. During the study period, 242 procedures were performed, the majority of them in children younger than 1 year, with an increasing trend towards F/F (p = 0.028, S = 11). The estimated incidence was 40.6 F/F per 10,000 inhabitants. Among all children who underwent F/F, the majority were breastfed for up to 1 month (101, 41.7%), followed by 4 to 5 months (56, 23.1%). There was no significant association between exclusive breastfeeding for 6 months and lingual frenectomy before 6 months of age (p = 0.444). Confirmation of the need for lingual frenectomy was associated with multidisciplinary assessment at referral (p < 0.001; Cramér's V = 0.268). It can be concluded that organization of the care process and the breastfeeding support movement may have had a positive influence on the management of cases and the upward trend towards F/F procedures. Multiprofessional assessment seemed to have an impact on the accuracy of referrals for cases requiring surgical intervention.

在这项研究中,对2017年至2022年在巴西圣保罗州里贝贝奥普雷托公共牙科服务的7岁以下儿童进行舌系带切开术/系带切除术(F/F)的转诊进行了评估。在这项纵向观察性回顾性研究中,通过健网系统(Power BI)平台访问电子医疗记录,收集以下变量:F/F发生率、与粘连症相关的症状报告、纯母乳喂养持续时间(EBF)、要求转诊的专业类别和多专业评估。描述性分析、变量之间的关联、组间比较和发病率进行了比较。显著性水平设为5%。在研究期间,共进行242例手术,其中以1岁以下儿童居多,F/F呈上升趋势(p = 0.028, S = 11)。估计发病率为每10,000居民40.6 F/F。在所有接受F/F的儿童中,大多数母乳喂养长达1个月(101,41.7%),其次是4至5个月(56,23.1%)。6个月纯母乳喂养与6个月前舌系带切除术之间无显著相关性(p = 0.444)。确认需要行舌系带切除术与转诊时的多学科评估相关(p < 0.001; cram’s V = 0.268)。可以得出结论,护理过程的组织和母乳喂养支持运动可能对病例管理和F/F程序的上升趋势产生了积极影响。多专业评估似乎对需要手术干预的病例转诊的准确性有影响。
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引用次数: 0
Exposure of the Brazilian population to risk factors for oral cancer. 巴西人口对口腔癌危险因素的暴露。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-10 eCollection Date: 2025-01-01 DOI: 10.1590/1807-3107bor-2025.vol39.105
Hannah Gil de Farias Morais, Lucas Melo da Costa, Renata Roque Ribeiro, Maria Helena Rodrigues Galvão, Angelo Giuseppe Roncalli, Márcia Cristina da Costa Miguel, Roseana de Almeida Freitas

The aim of this study was to investigate the profile of the Brazilian population exposed to risk factors for oral cancer, as well as the profile of patients in the high-risk group for this disease in Brazil. This study relied on a cross-sectional design, utilizing secondary data from the 2020 National Health Survey (PNS). The database used contained information on 90,846 individuals aged 18 and older. The dependent variable was "High-risk group for oral cancer development" and the independent variables were grouped into biological characteristics, educational level, access to health services, and self-care practices. In the multivariate analysis, odds ratios of outcomes were assessed using a logistic regression model. Individuals of white ethnicity, with low levels of education, residing in rural areas, not registered in the Family Health Strategy program, who have rarely or never seen a dentist, self-assessing their general health as poor, and lacking regular physical exercise were more likely to be in the high-risk group for the development of oral cancer. The data from the 2020 National Health Survey (PNS) demonstrate that a large portion of the Brazilian population is exposed to risk factors for oral cancer. This highlights the disparities in access to medical and dental health services, as well as in the educational and preventive interventions by healthcare professionals regarding risk factors for oral cancer.

本研究的目的是调查巴西口腔癌危险因素暴露人群的概况,以及巴西口腔癌高危人群的概况。本研究采用横断面设计,利用了2020年全国健康调查(PNS)的二手数据。所使用的数据库包含90,846名18岁及以上个人的信息。因变量为“口腔癌发展的高危人群”,自变量分为生物学特征、教育水平、获得卫生服务的机会和自我保健实践。在多变量分析中,使用逻辑回归模型评估结果的优势比。受教育程度低、居住在农村地区、未在家庭健康战略方案中登记、很少或从未看过牙医、自我评估自己的总体健康状况较差、缺乏定期体育锻炼的白人个体更有可能成为口腔癌发展的高风险群体。2020年全国健康调查(PNS)的数据表明,很大一部分巴西人口面临口腔癌的危险因素。这突出了在获得医疗和牙科保健服务以及保健专业人员就口腔癌风险因素进行教育和预防干预方面的差异。
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引用次数: 0
Factors associated with adherence to post-exposure prophylaxis among dental professionals in Brazil. 巴西牙科专业人员接触后预防依从性的相关因素
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-10 eCollection Date: 2025-01-01 DOI: 10.1590/1807-3107bor-2025.vol39.107
Gustavo Correia Basto da Silva, Ana Carolina Marques Medeiros Viani, Angélica Maria Cupertino Lopes Marinho, Isabela Almeida Pordeus, Mauro Henrique Nogueira Guimarães de Abreu

This study analyzed the influence of sociodemographic, occupational, and accident-related factors on adherence to post-exposure prophylaxis (PEP) among dental professionals. A cross-sectional study was conducted using secondary data from the Brazilian Notifiable Diseases Information System, covering incidents of biological material exposure from 2018 to 2023 across all federal units. PEP adherence was the outcome analyzed, and related factors included sociodemographic, occupational, and accident characteristics. Descriptive, bivariate, and multivariate logistic regression analyses were performed (α = 5%). A total of 15,650 notifications involving dental professionals were analyzed, representing 3.91% of all cases of occupational exposure, with a PEP adherence rate of 91.0%. The exposed professionals had a mean age of 32.5 years (SD = 10.4), were predominantly women (76.6%), of White race/ethnicity (65.4%), and had higher education (79.7%). The mean work experience was 3.6 years (SD = 6.8). In the adjusted model, adherence was associated with lower educational attainment (OR = 0.71; 95%CI: 0.58-0.88), younger age (OR = 0.99; 95%CI: 0.98-0.99), and longer work experience (OR = 1.02; 95%CI: 1.01-1.03). Percutaneous exposure (OR = 1.39; 95%CI: 1.16-1.67), contact with blood (OR = 1.47; 95%CI: 1.18-1.82), and dental procedure-related accidents (OR = 1.35; 95%CI: 1.07-1.70) increased the likelihood of adherence. Hepatitis B vaccination (OR = 1.96; 95%CI: 1.62-2.36) was associated with increased adherence to PEP. Adherence to PEP was influenced by multiple factors, highlighting the need for effective strategies to improve adherence and occupational safety among these professionals.

本研究分析了社会人口学、职业和事故相关因素对牙科专业人员暴露后预防(PEP)依从性的影响。利用巴西法定疾病信息系统的二手数据进行了一项横断面研究,涵盖了2018年至2023年所有联邦单位的生物材料暴露事件。结果分析了PEP依从性,相关因素包括社会人口学、职业和事故特征。进行描述性、双变量和多变量逻辑回归分析(α = 5%)。共分析了15650份涉及牙科专业人员的通报,占所有职业暴露病例的3.91%,PEP依从率为91.0%。暴露的专业人员平均年龄为32.5岁(SD = 10.4),主要为女性(76.6%),白人(65.4%),受过高等教育(79.7%)。平均工作经验为3.6年(SD = 6.8)。在调整后的模型中,依从性与较低的受教育程度(OR = 0.71; 95%CI: 0.58-0.88)、较年轻(OR = 0.99; 95%CI: 0.98-0.99)和较长的工作经验(OR = 1.02; 95%CI: 1.01-1.03)相关。经皮接触(OR = 1.39; 95%CI: 1.16-1.67)、接触血液(OR = 1.47; 95%CI: 1.18-1.82)和牙科手术相关事故(OR = 1.35; 95%CI: 1.07-1.70)增加了依从性的可能性。乙肝疫苗接种(OR = 1.96; 95%CI: 1.62-2.36)与PEP依从性增加相关。对PEP的依从性受到多种因素的影响,强调需要有效的策略来提高这些专业人员的依从性和职业安全。
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引用次数: 0
Prediction of marginal adaptation failure in restorations of non-carious cervical lesions, based on machine learning. 基于机器学习的非龋齿宫颈病变修复边缘适应失败预测。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-10 eCollection Date: 2025-01-01 DOI: 10.1590/1807-3107bor-2025.vol39.106
Thalita de Paris Matos Bronholo, Pedro Felipe de Jesus Freitas, Aline Xavier Ferraz, Kaliane Rodrigues da Cruz, Michael Willian Favoreto, Flares Baratto-Filho, Alessandra Reis, Alessandro Dourado Loguercio, Cristiano Miranda de Araujo

Marginal adaptation failure in noncarious cervical restorations (NCCRS) significantly compromises restoration longevity and adversely impacts patient outcomes. early identification of high-risk restorations is therefore of clinical importance. This study aimed to develop and evaluate a supervised machine learning (ML) model capable of predicting the risk of marginal adaptation failure in NCCRS within 18 months following treatment. A total of 262 restorations were analyzed, incorporating multiple clinical variables, including adhesive system used, cavity geometry, degree of dentin sclerosis, incisogingival height, tooth characteristics, and patient age. Seven supervised ml algorithms were trained and assessed: decision tree, support vector machine (SVM), gradient boosting, k-nearest neighbors (KNN), logistic regression, multilayer perceptron, and random forest. model performance was evaluated using fivefold cross-validation and standard metrics, including the area under the receiver operating characteristic curve (AUC), accuracy, recall, precision, and F1 score. Key predictive features identified were incisogingival height, patient age, and type of adhesive system. the auc values ranged from 0.72 (95% confidence interval [95%CI]: 0.57-0.88) to 0.52 (95%CI: 0.51-0.83), and recall values ranged from 0.77 (95%CI: 0.66-0.89) to 0.53 (95%CI: 0.40-0.66). Among the tested algorithms, SVM, gradient boosting, and KNN demonstrated superior predictive performance. these findings suggest that ml models can serve as effective tools for predicting restoration failure and may assist clinicians in optimizing post-treatment monitoring and follow-up strategies for patients with NCCRS.

无龋宫颈修复体(NCCRS)的边缘适应失败显著影响修复体的寿命,并对患者的预后产生不利影响。因此,早期识别高风险修复体具有临床重要性。本研究旨在开发和评估一种有监督的机器学习(ML)模型,该模型能够预测ncrs治疗后18个月内边际适应失败的风险。对262个修复体进行分析,纳入多个临床变量,包括使用的粘接剂系统、牙本质几何形状、牙本质硬化程度、切龈高度、牙齿特征和患者年龄。我们训练并评估了七种有监督的机器学习算法:决策树、支持向量机(SVM)、梯度增强、k近邻(KNN)、逻辑回归、多层感知器和随机森林。使用五重交叉验证和标准指标评估模型的性能,包括接收者工作特征曲线下面积(AUC)、准确率、召回率、精度和F1评分。确定的关键预测特征是切龈高度,患者年龄和粘接剂系统类型。auc值范围为0.72(95%可信区间[95% ci]: 0.57 ~ 0.88) ~ 0.52 (95% ci: 0.51 ~ 0.83),召回值范围为0.77 (95% ci: 0.66 ~ 0.89) ~ 0.53 (95% ci: 0.40 ~ 0.66)。在测试算法中,SVM、梯度增强和KNN表现出较好的预测性能。这些发现表明,ml模型可以作为预测修复失败的有效工具,并可以帮助临床医生优化ncrs患者的治疗后监测和随访策略。
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引用次数: 0
After all, what is the proper use of Kappa statistics in oral health surveys? What don't manuals tell us? 毕竟,Kappa统计数据在口腔健康调查中的正确用途是什么?手册上没有告诉我们什么?
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-10-10 eCollection Date: 2025-01-01 DOI: 10.1590/1807-3107bor-2025.vol39.102
Andréa Videira Assaf, Renato Pereira da Silva, Fábio Luiz Mialhe, Antonio Carlos Pereira

The aim of this study was to elucidate, unclear points of the "Oral Health Survey: basic methods", of the World Health Organization (WHO), relative to reproducibility (encompassed reliability and agreement) issues during examiners' calibration. Thus, Kappa statistics and percent agreement were calculated for a sample of 10 12-year-old schoolchildren examined by 1 gold standard examiner and 5 dentists from Nova Friburgo, RJ, Brazil, in 2018, under the WHO and SB Brasil 2010 Project settings. Weighted Kappa was used to measure reliability between 2 examiners, and Fleiss' Kappa for 5 examiners. Tooth-to-tooth reliability was also assessed. The results showed that, although the choice of different settings invariably produced different reliability and agreement values, this approach was feasible, coherent and even desirable depending on the purpose of an epidemiological survey conducted. Kappa values were slightly lower in the SB Brasil 2010 Project setting. The results for tooth-to-tooth reliability, in turn, allowed identification of teeth (in this sample, teeth 17, 23, 27, 34, 37, 44, 45, and 47) for which additional examiner calibrations would be necessary. It is concluded that providing additional information for inclusion in the WHO manual, such as the possibility of varying the setting, adopting the tooth-by-tooth unit, and selecting the correct type of Kappa statistic depending on the number of examiners, within a multilevel calibration proposal, may result in more reliable results during the calibration stage.

本研究的目的是阐明世界卫生组织(WHO)的“口腔健康调查:基本方法”中与审查员校准时的可重复性(包括可靠性和一致性)问题有关的不明确点。因此,在世卫组织和SB Brasil 2010项目设置下,对2018年由巴西RJ州新弗里堡的1名金标准检查员和5名牙医检查的10名12岁学童样本进行Kappa统计和百分比一致性计算。采用加权Kappa法测量2名考官之间的信度,采用Fleiss Kappa法测量5名考官之间的信度。牙对牙的可靠性也进行了评估。结果表明,尽管选择不同的设置总是产生不同的可靠性和一致性值,但这种方法是可行的,连贯的,甚至是可取的,这取决于所进行的流行病学调查的目的。在SB巴西2010项目设置中,Kappa值略低。牙齿对牙齿可靠性的结果,反过来,允许识别牙齿(在这个样本中,牙齿17、23、27、34、37、44、45和47),对于额外的检查员校准是必要的。结论是,在多层校准建议中提供附加信息以纳入世卫组织手册,例如改变设置的可能性,采用逐牙单元,以及根据检验员数量选择正确的Kappa统计类型,可能会在校准阶段产生更可靠的结果。
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引用次数: 0
Predictive models of weakness among older adults: the contribution of oral health indicators. 老年人虚弱的预测模型:口腔健康指标的贡献。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-29 eCollection Date: 2025-01-01 DOI: 10.1590/1807-3107bor-2025.vol39.064
Ana Lúcia Schaefer Ferreira de Mello, Mateus Cardoso Pereira, Daniela de Rossi Figueiredo, Eleonora D'Orsi, Marco Aurélio Peres, Karen Glazer Peres

Poor oral health can negatively impact overall health and quality of life. Understanding how oral health predicts weakness in older adults is critical, since weakness increases the risk of health outcomes. However, the predictive role of oral health indicators in weakness among older adults remains unclear. This study assessed the ability of oral health indicators to predict weakness using data from Brazil's EpiFloripa Aging cohort study. Predictive validity was evaluated in a sample of older adults participating in the cohort's second (n = 440) and third (n = 347) waves. Self-reported sociodemographic, general health, and oral health variables were analyzed, with weakness diagnosed using cut-off points for handgrip strength. Predictive models incorporating sociodemographic, general health, and oral health variables were tested. Receiver operating characteristic curves, sensitivity and specificity, and positive and negative predictive values were calculated. Approximately 45.9% of the participants had two to three compromised oral health indicators during the second wave, and the five-year incidence of weakness was 31.9%. Oral health indicators and the oral frailty score did not enhance the prediction of weakness compared to models based solely on demographic, socioeconomic, and general health variables. However, models including oral health indicators demonstrated predictive accuracy comparable to those with demographic, socioeconomic, and general health variables. Sensitivity values were low (3.70-6.48%), while specificity values were high (>99%), with accuracy ranging from 0.64 to 0.71. These findings suggest that oral health indicators offer comparable predictive validity for weakness as sociodemographic and general health models, potentially serving as useful tools for health teams in screening older adults for weakness.

口腔健康状况不佳会对整体健康和生活质量产生负面影响。了解口腔健康如何预测老年人的虚弱是至关重要的,因为虚弱会增加健康结果的风险。然而,口腔健康指标在老年人虚弱中的预测作用仍不清楚。本研究利用巴西EpiFloripa衰老队列研究的数据,评估了口腔健康指标预测虚弱的能力。在参与队列第二波(n = 440)和第三波(n = 347)的老年人样本中评估预测效度。分析了自我报告的社会人口统计、一般健康和口腔健康变量,并使用握力的截止点诊断虚弱。对纳入社会人口统计学、一般健康和口腔健康变量的预测模型进行了测试。计算受试者工作特征曲线、敏感性和特异性、阳性预测值和阴性预测值。大约45.9%的参与者在第二波期间有两到三项口腔健康指标受损,五年虚弱发生率为31.9%。与仅基于人口统计学、社会经济和一般健康变量的模型相比,口腔健康指标和口腔虚弱评分并没有增强对虚弱的预测。然而,包括口腔健康指标的模型显示出与人口统计、社会经济和一般健康变量相当的预测准确性。灵敏度低(3.70 ~ 6.48%),特异度高(bb0 ~ 99%),准确度为0.64 ~ 0.71。这些发现表明,口腔健康指标对虚弱的预测效度与社会人口统计学和一般健康模型相当,可能成为卫生团队筛查老年人虚弱的有用工具。
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引用次数: 0
Oral mucosal findings in ambulatory patients with inflammatory bowel disease. 炎症性肠病患者的口腔黏膜表现。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-15 eCollection Date: 2025-01-01 DOI: 10.1590/1807-3107bor-2025.vol39.095
Lilly Esquivel-Pedraza, Laura Fernández-Cuevas, Isianel Delgado-Martínez, Alba Cicero-Casarrubias, María Del Pilar Milke-García, Eire Mairan Chang-Bool, Linda Margarita Barragán-Heredia, Jenny Maldonado-Molina, Renata Lucrecia Rivera-Flores, Jesús Kazuo Yamamoto-Furusho, Judith Domínguez-Cherit, Silvia Méndez-Flores

A cross-sectional study was carried out among patients with ulcerative colitis (UC) and Crohn's disease (CD) in order to determine the frequency of oral mucosal lesions or conditions (OL), as well as to analyze its relationship with some clinical and laboratory parameters. Epidemiologic, clinical, and laboratory data were considered. Statistics included univariate and multivariate analyses. Ninety patients [46 (51.1%) males] were included [median age: 43 years (range 18-79 years)]. UC was diagnosed in 65 (72.2%) patients; CD in 25 (27.8%) patients; and inactive CD was detected in 78 (86.6%) patients. All patients (100%) had OL; fissured tongue was the most frequent finding [68 (75.6%)]. Furred tongue was more common in UC than in CD patients [45 (69.2%) vs. 11(44.0%); p = 0.03]; lower levels of hemoglobin were more often detected in mucosal pallor [(median (Md) =12.1 vs. 14.4g/dL); p = 0.02] than in other OLs. Higher frequency of melanosis was observed when oral rinses were used [37 (71.2%) vs. 15 (28.8%)]; p = 0.03], compared to those who did not use them. A higher risk of varix [OR: = 37.6 (95%CI: 4.7-298.9), p < 0.001], leukoedema [OR: 5.8 (95%CI: 1.4-24.2); p = 0.004], candidosis [OR: 3.9 (95%CI: 1.4-10.6); p = 0.05], fissured tongue [OR: 3.8 (95%CI: 1.2-11.5); p = 0.01], and all infectious processes analyzed collectively [OR: 3.6 (95%CI: 1.3-9.8); p = 0.03], was found in patients older than 45 years than in younger ones. Also, patients with fissured tongue presented a higher risk of having candidosis than those without this condition [OR: 6.1 (95%CI: 2.1-17.5); p = 0.007]. OLs were highly frequently observed in UC and CD patients. Age (> 45 years), low levels of hemoglobin, use of mouthwashes, among other variables, were predictive factors of OL in these patients; thus, their assessment and detection in inflammatory bowel disease should be emphasized.

我们对溃疡性结肠炎(UC)和克罗恩病(CD)患者进行了横断面研究,以确定口腔黏膜病变或状况(OL)的频率,并分析其与一些临床和实验室参数的关系。考虑了流行病学、临床和实验室数据。统计包括单变量和多变量分析。纳入90例患者[46例(51.1%)男性][年龄中位数:43岁(18-79岁)]。65例(72.2%)患者诊断为UC;CD 25例(27.8%);非活动性乳糜泻78例(86.6%)。所有患者(100%)均有OL;舌裂是最常见的症状[68例(75.6%)]。舌毛在UC患者中比在CD患者中更常见[45例(69.2%)比11例(44.0%);P = 0.03];较低水平的血红蛋白更常见于粘膜苍白(中位数(Md) =12.1 vs. 14.4g/dL);p = 0.02]。使用口腔冲洗液时,黑变的发生率更高[37人(71.2%)对15人(28.8%)];P = 0.03],与未使用药物的患者相比。静脉曲张[OR: = 37.6 (95%CI: 4.7-298.9), p < 0.001]、脑白质水肿[OR: 5.8 (95%CI: 1.4-24.2);p = 0.004],念珠菌病[OR: 3.9 (95%CI: 1.4-10.6);p = 0.05],舌裂[OR: 3.8 (95%CI: 1.2 ~ 11.5);p = 0.01],并对所有感染过程进行综合分析[OR: 3.6 (95%CI: 1.3-9.8);P = 0.03],年龄大于45岁的患者多于年龄较小的患者。此外,有舌裂的患者患念珠菌病的风险高于没有舌裂的患者[OR: 6.1 (95%CI: 2.1-17.5);P = 0.007]。ol在UC和CD患者中非常常见。年龄(40 ~ 45岁)、低血红蛋白水平、使用漱口水以及其他变量是这些患者OL的预测因素;因此,它们在炎症性肠病中的评估和检测应得到重视。
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引用次数: 0
Polymorphisms and environmental factors associated with orofacial clefts as potential markers for oral cancer risk. 与口面裂隙相关的多态性和环境因素作为口腔癌风险的潜在标志。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-15 eCollection Date: 2025-01-01 DOI: 10.1590/1807-3107bor-2025.vol39.089
Adriana Mendonça da Silva, Michelle Miranda Lopes Falcão, Valéria Souza Freitas, Alexandre Resende Vieira

The etiological intersection between orofacial clefts and oral cancer may involve environmental factors modulating gene expression in shared biological pathways. This study aimed to investigate the association between orofacial clefts and oral potentially malignant disorders or oral squamous cell carcinoma, focusing on genetic variants and environmental risk factors. A case-control design was employed, comprising 48 histologically confirmed cases of oral potentially malignant disorders or oral squamous cell carcinoma and 96 age- and sex-matched controls. Information on family history of orofacial cleft, and biological and environmental risk factors, was collected through interviews. Genomic DNA was extracted from saliva samples and genotyped for rs1533767 (WNT11), rs9879992 (GSK3B), and rs3923087 and rs11867417 (AXIN2). Unadjusted and adjusted odds ratios (OR) for the associations between family history of orofacial cleft and oral potentially malignant disorders/oral cancer, and between environmental risk factors and oral potentially malignant disorders/oral cancer were calculated using STATA software. Genotype and allele frequency comparisons between groups were conducted using PLINK Software. Statistical significance was defined as p<0.05 and 95% confidence interval (95%CI). No statistically significant association was found between family history and orofacial clefts (p = 0.52). However, place of residence (adjusted OR:5.46, p < 0.001, 95%CI: 3.76-63.543), and three genetic variants-rs1533767 (OR: 1.94, p = 0.042, 95%CI: 1.018-3.694), rs3923087 (OR: 0.58, p = 0.038, 95%CI: 0.344-0.974), rs11867417 (OR: 0.51, p = 0.010, 95%CI: 0.304-0.857)-were associated with oral potentially malignant disorders and oral squamous cell carcinoma. These findings suggest that specific environmental risk factors and genetic variants may be associated with increased susceptibility to oral potentially malignant disorders and oral cancer.

唇腭裂和口腔癌之间的病因交叉可能涉及环境因素在共享的生物学途径中调节基因表达。本研究旨在探讨口腔颌面部裂与口腔潜在恶性疾病或口腔鳞状细胞癌之间的关系,重点关注遗传变异和环境危险因素。采用病例对照设计,包括48例组织学证实的口腔潜在恶性疾病或口腔鳞状细胞癌病例和96例年龄和性别匹配的对照组。通过访谈收集了口面部裂家族史、生物和环境风险因素的信息。提取唾液样本的基因组DNA,分型rs1533767 (WNT11)、rs9879992 (GSK3B)、rs3923087和rs11867417 (AXIN2)。使用STATA软件计算口面部裂家族史与口腔潜在恶性疾病/口腔癌、环境危险因素与口腔潜在恶性疾病/口腔癌之间的未调整和调整比值比(OR)。采用PLINK软件进行组间基因型和等位基因频率比较。统计学显著性定义为p
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引用次数: 0
Factors associated with the effectiveness of oral health promotion in the Family Health Strategy. 家庭健康策略中与促进口腔健康成效有关的因素。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-15 eCollection Date: 2025-01-01 DOI: 10.1590/1807-3107bor-2025.vol39.096
Suyene de Oliveira Paredes, Franklin Delano Soares Forte, Edson Hilan Gomes de Lucena, Andreza Cristina de Lima Targino Massoni, Maria Helena Rodrigues Galvão

This study investigated associations between sociodemographic and professional profiles, work-related factors, and the effectiveness of oral health promotion strategies implemented by dentists in the Family Health Strategy. A cross-sectional study was conducted with 211 dentists working in Oral Health Teams within the Family Health Strategy in the state of Paraíba, Brazil. Data were collected online using a validated instrument. A matrix encompassing the core values and pillars of health promotion was employed to evaluate the effectiveness of oral health promotion strategies. Data were analyzed using Poisson regression (p < 0.05), and all analyses were performed in Stata, version 14. Greater effectiveness of oral health promotion strategies was associated with mixed Oral Health Teams (urban and rural coverage) (PR = 1.54; 95%CI: 1.154-2.076; p = 0.003) and with dentists under temporary contracts (PR = 1.67; 95%CI: 1.240-2.250; p = 0.001). The effectiveness of oral health promotion strategies was associated with work-related factors. Evaluations of oral health promotion practices are essential to support improvements in oral health management. The findings highlight the need to strengthen these practices through professionals who, in addition to having a defined employment relationship and a structured work process, value oral health promotion as a key component of care.

本研究调查了社会人口学和专业概况、工作相关因素以及牙医在家庭健康战略中实施的口腔健康促进策略的有效性之间的关系。在巴西Paraíba州的家庭保健战略框架内,对在口腔保健小组工作的211名牙医进行了一项横断面研究。使用经过验证的仪器在线收集数据。采用包含健康促进核心价值和支柱的矩阵来评估口腔健康促进策略的有效性。数据分析采用泊松回归(p < 0.05),所有分析均在Stata版本14中进行。口腔健康促进策略的更大有效性与混合口腔保健小组(城市和农村覆盖)(PR = 1.54; 95%CI: 1.154-2.076; p = 0.003)和临时合同牙医(PR = 1.67; 95%CI: 1.240-2.250; p = 0.001)相关。口腔健康促进策略的有效性与工作相关因素有关。对促进口腔健康的做法进行评价对于支持改善口腔健康管理至关重要。调查结果强调,需要通过专业人员加强这些做法,这些专业人员除了具有明确的雇佣关系和结构化的工作流程外,还将促进口腔健康视为护理的关键组成部分。
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引用次数: 0
Effect of dentition status on perceived mobility limitation among older Brazilian adults: a cohort study. 牙列状态对巴西老年人感知活动受限的影响:一项队列研究。
IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-08 eCollection Date: 2025-01-01 DOI: 10.1590/1807-3107bor-2025.vol39.086
Fabiola Bof de Andrade, Renata Lara Freitas, Yeda Aparecida de Oliveira Duarte, Jair Lício Ferreira Santos

This study aimed to evaluate the longitudinal effect of dentition status on the perceived mobility limitation of community-dwelling Brazilian older adults. This cohort study used data from individuals who participated in the second (2006), third (2010), and fourth (2015) waves of the Health Well-being and Aging Study, conducted in the urban region of the city of São Paulo, Brazil, with adults aged 60 years and older. Mobility limitation was assessed in all waves according to reports of difficulty in performing seven activities, with higher scores representing a higher number of limitations. The independent variables of interest were number of teeth, use of dental prostheses, impact of oral health on functionality, and presence of periodontal pockets. Oral health measures were assessed by dentists, in all waves, during a clinical oral examination. The generalized linear mixed model with a Poisson distribution was used to assess longitudinal associations. All the variables were treated as time-varying in the analysis. Older adults with 20 or more teeth had a lower risk of mobility limitation than edentulous individuals, while the impact of oral health on functionality was associated with an increased risk. Similar findings were observed among dentate individuals. Periodontal disease was not associated with the outcome in dentate individuals. The associations were constant over time. The number of teeth and the impact of oral health on functionality are risk factors for mobility limitation, underscoring the importance of maintaining functional dentition for healthy aging.

本研究旨在评估牙列状态对巴西社区老年人感知活动限制的纵向影响。这项队列研究使用的数据来自参加第二波(2006年)、第三波(2010年)和第四波(2015年)健康福祉与老龄化研究的个人,该研究在巴西圣保罗的城市地区进行,年龄在60岁及以上。根据执行7项活动的难度报告评估所有波的活动限制,得分越高表示限制数量越多。感兴趣的独立变量是牙齿的数量、义齿的使用、口腔健康对功能的影响以及牙周袋的存在。在临床口腔检查期间,由牙医评估所有阶段的口腔健康措施。采用具有泊松分布的广义线性混合模型来评估纵向关联。在分析中,所有变量都被视为时变的。与无牙者相比,拥有20颗或更多牙齿的老年人活动受限的风险较低,而口腔健康对功能的影响与风险增加有关。在有齿个体中也观察到类似的结果。牙周病与有牙个体的结果无关。随着时间的推移,这种联系是不变的。牙齿的数量和口腔健康对功能的影响是活动受限的危险因素,强调了保持牙齿功能对健康老龄化的重要性。
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Brazilian oral research
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