Brazilian oral research最新文献

Oral squamous cell carcinoma (OSCC) remains the most prevalent neoplasm of the head and neck. In recent decades, the incidence and prevalence of OSCC have not significantly changed, highlighting the critical need to develop and implement new risk assessment measures. The present study aimed to define argyrophilic proteins of the nucleolar organizer region (AgNOR) cut-off risk points by oral exfoliative cytological smears comparing specialized humans with a convolutional neural network (CNN) system AgNOR Slide-Image Examiner. This study included four experimental groups: control, exposure to carcinogens (alcohol and tobacco), oral potentially malignant disorders, and OSCC. In the first phase, 50 cells were used for AgNOR quantification. In the second phase, AgNOR quantification was established in an automated manner using an AgNOR System - Slide Examiner (captured - bounding-boxed - CNN analysis). In phase 1, the cut-off point for considering a smear as suspicious was established at 3.69 AgNORs/nucleus with sensitivity of 86%, specificity of 93%, and accuracy of 90%. In phase 2, the analysis of the intraclass correlation coefficient of AgNORs attributed to the system and human was 0.896 (95% confidence interval = 0.875-0.915; p < 0.0001), and this quantification with the CNN was 20 min compared to 67 h, considering human analysis. The AgNOR Slide-Image Examiner successfully differentiated the nuclei and accurately quantified the number of NORs in oral cytological smears. The cut-off risk point of 3.69 AgNOR/nucleus indicates a suspicious sample may contribute to improvements in oral cancer screening.

The aim of this study was to evaluate the association of body image perception and self-assessment of oral health with other associated factors in a sample of Brazilian adolescents. This cross-sectional study involved a total of 281 adolescents aged 14 to 19 years enrolled in 29 public schools from May 2021 to December 2023 in the urban area of Juiz de Fora, state of Minas Gerais, Brazil. The total enrollment of 9,502 participants in the first stage of the study () was considered for sample size calculation. The prevalence of negative self-assessment of oral health in the adolescent population was estimated at 18%, with a standard error of 1%, a 95% confidence interval, and a 20% loss to follow-up. Participants completed a questionnaire via the Google Forms platform, which gathered information on their socioeconomic status, self-perception of body image, self-assessment of oral health, and self-esteem. Bivariate analysis and logistic regression models were used to evaluate the associations between variables. Variables with p < 0.10 in the bivariate analysis were included in the logistic regression model. Variables with p < 0.05 were retained in the final model. The final logistic regression model revealed that adolescents with a higher socioeconomic status rated their oral health as excellent or good. Additionally, those who reported not living with their parents and had a low level of self-esteem had a poor oral health self-assessment. Adolescents' perception of their body image was not associated with oral health self-assessment. On the other hand, socioeconomic factors, family structure, and self-esteem influenced adolescents' oral health self-assessment.

This study aimed to investigate oral conditions and their impact on salivary biochemical parameters in institutionalized individuals with and without substance use disorder. This was an epidemiological, cross-sectional, and clinical study. It included two groups, institutionalized individuals with substance use disorder (SUD group) and without substance use disorder (control group), each consisting of 60 participants. Salivary samples were analyzed for various parameters, while oral conditions were assessed using the DMFT index, community periodontal index, clinical attachment loss index, and need for prosthesis. Statistical analysis included the Mann-Whitney U test, t-tests, and correlation analysis (p ≤ 0.050). The SUD group showed a higher need for dental prostheses (p < 0.001) and more pronounced dental erosion (p < 0.001). This group also exhibited elevated DMFT indices, with significant associations in sextants with calculus (p = 0.010), periodontal pockets (p < 0.001), and attachment loss of 12 mm or more (p = 0.036). Regarding salivary parameters, the SUD group had high cortisol levels and significant correlations between uric acid and bleeding sextants (p = 0.024), salivary amylase and decayed teeth (p = 0.002), cortisol and the DMFT index (p = 0.045), and cortisol and the absence of DMFT (p = 0.042). In conclusion, individuals in the SUD group exhibited worse oral conditions than did those in the control group, suggesting a relationship between drug addiction and increased cortisol, uric acid, and salivary amylase levels.

The aim of this study was to verify the role of Brazilian researchers in publications related to photobiomodulation (PBM) in the field of oral medicine. We examined ten years from 2012 to 2022 across 16 journals. Our analysis included scientific publications with a Brazilian author either in the first or last position and publications from international collaborations. The search yielded 43,525 publications. After examining titles and abstracts, 269 studies were categorized as having a specific emphasis on PBM in oral medicine, of which 147 (54.6%) were undertaken by research groups based in Brazil. The citations ranged from 1 to 149 (an average of 31 per manuscript). The male-to-female ratio of first and last author was 1:2 and 1:1.4, respectively. Brazilian involvement in the field of PBM was significant, with a marked focus on basic research, clinical applications, and technological advances. Our results also underscore the remarkable participation of female researchers in pivotal roles. Brazilian publications positively impacted healthcare worldwide using PBM in oral medicine, as evidenced by the substantial number of articles published and the citations of these articles received.

[This corrects the article doi: 10.1590/1807-3107bor-2025.vol39.017].

Preventive maintenance in pediatric dentistry is essential for monitoring oral health and promoting healthy habits. This study aimed to evaluate how the frequency of follow-up appointments, as well as sex- and age-related differences, impact the probability of referral for curative treatment among pediatric dentistry patients at a Brazilian dental school. This retrospective longitudinal study included dental records of patients who had their first appointment between the second half of 2013 and the second half of 2019, completed treatment, and returned for at least one check-up visit. Descriptive and survival analyses were performed. A total of 296 dental records were evaluated, comprising 47.6% female and 52.4% male patients. The likelihood of referral to curative treatment increased with longer follow-up intervals, reaching 18.9% at six months and 82.7% at 48 months. Patients aged 9 years or younger were 2.07 times more likely to be referred to curative treatment than those aged 10 years or older. No significant difference was observed in referral probability between boys and girls. Longer intervals between check-up visits increased the likelihood of referral to curative treatment, which was higher among older children. Establishing personalized follow-up intervals based on individual patient needs is crucial for maintaining oral health.

The objective of this study was to estimate the prevalence of comorbidities among people living with HIV/AIDS (PLWHIV) attending a dental outpatient clinic and discuss the impact of these comorbidities on dental management. A cross-sectional observational study evaluated 238 PLWHIV attending a specialized dental outpatient clinic in Brazil. We collected sociodemographic data, self-reported and physician-diagnosed comorbidities, hemogram results, CD4+ T cell count, viral load, use of combined antiretroviral therapy (cART), and information on harmful habits. The most prevalent comorbidities were sexually transmitted infections (STIs) (116/238; 48.7%), psychiatric disorders (105/238; 44.1%), and lipodystrophy (97/238; 40.8%). Men were more likely to have STIs (OR 4.0) and tuberculosis (OR: 2.5) (p < 0.05). Age ≥ 50 years increased the risk of diabetes mellitus by 2.6 times (p < 0.05). The risk of lipodystrophy (OR: 2.99, 95%CI 1.44-6.19) and psychiatric disorders (OR: 2.13, 95%CI 1.01-4.47) was greater in those who had been diagnosed with HIV for more than 20 years. In summary, psychiatric disorders and severe hematological alterations, such as anemia and neutropenia, are significant comorbidities that may limit dental treatment of HIV-positive patients. These findings underscore the need for integrated medical and dental care to address the complex health needs of PLWHIV.

The iVAC system combines ultrasonic activation with negative-pressure irrigation, highlighting the importance of determining its vibration characteristics. This study aimed to evaluate the oscillation characteristics of the iVAC system using laser Doppler vibrometry and to compare them with those of metallic inserts used for ultrasonic irrigation. Four ultrasonic inserts-Irrisonic, Nitisonic, Ultra X Blue, and iVAC-were attached to an ultrasonic unit, secured in a holder, and operated at a power setting of 15%. A laser scanning vibrometer was used to scan the first four millimeters of each insert. Each measurement, lasting approximately 20 seconds, was repeated ten times per insert and performed at millimeter intervals. Displacement amplitude and frequency data were recorded for each insert. Furthermore, scanning electron microscopy was employed to evaluate the surface finish of the inserts, and their elemental compositions were analyzed using energy-dispersive X-ray spectroscopy (EDS). Analysis of variance and Tukey's test were conducted to compare the performance of the inserts. The displacement amplitudes showed significant differences between inserts and among the scanned points (p < 0.05). All inserts demonstrated ultrasonic vibration frequencies exceeding 20 kHz. EDS analysis revealed that the elemental composition of the E1-Irrisonic tips was consistent with stainless steel. In contrast, the Nitisonic insert displayed a chemical composition characteristic of an equiatomic nickel-titanium (NiTi) alloy, whereas the Ultra X Blue insert contained additional elements beyond NiTi. The characteristics and composition of ultrasonic inserts significantly influence their displacement amplitude and vibration frequency. At the tested activation power, the iVAC insert, made of the organic thermoplastic polymer polyether ether ketone (PEEK), demonstrated an ultrasonic vibration pattern but exhibited the lowest oscillation amplitude among the inserts.

Objectively evaluating an individual's capacity for food fragmentation (masticatory performance) is crucial for understanding oral physiology and dental rehabilitation processes. Our aim was to conduct a bibliometric analysis of the literature focusing on masticatory performance. We conducted a survey in Web of Science up to August 31, 2024, applying specific category filters. Two calibrated reviewers manually tabulated the data, extracting information on title, authorship, keywords, institutions, countries, number of citations, year of publication, journal title, study design, masticatory test, population, and dentition status. VosViewer software generated collaborative network maps, while JAMOVI was used to perform ANOVA and Poisson regression analyses. The selection process resulted in 814 articles published between 1950 and 2024, with a recent increase to at least 50 articles per year. The average impact factor was 3.16, with around 30 citations per article. Citations were significantly influenced by the masticatory performance technique, publication year, and journal impact factor. The comminution test was the most prevalent (n = 411). Most studies focused on adults (n = 420) and older adults (n = 361), in which natural dentition (n = 404) and complete dentures (n = 214) were the most widely assessed parameters. The most frequent study designs were cross-sectional (n=489) and prospective (n = 145). The leading countries were Japan (n=202), Brazil (n=134), and the Netherlands (n = 69), and the Journal of Oral Rehabilitation was the most recurrent journal (n = 162). This study highlights the growing interest in evaluating masticatory performance, with a significant increase in publications over the years. This study highlights the need for further research involving children and longitudinal study designs, as well as studies evaluating rehabilitations with removable partial denture and implant-supported prostheses.