Pub Date : 2017-04-11DOI: 10.15406/JHVRV.2017.05.00159
W. Tariq
{"title":"Poliomyelitis, Security Issues and Pakistan","authors":"W. Tariq","doi":"10.15406/JHVRV.2017.05.00159","DOIUrl":"https://doi.org/10.15406/JHVRV.2017.05.00159","url":null,"abstract":"","PeriodicalId":92670,"journal":{"name":"Journal of human virology & retrovirology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42621098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-04DOI: 10.15406/JHVRV.2017.05.00156
Sharma Nk, Awasthi Lp
Antiviral proteins were isolated, from host plants, following treatment with an antiviral glycoprotein, extracted from the roots of Boerhaavia diffusa plants. It was found to be active against isometric as well as an isometric viruses in their respective hypersensitive and systemic hosts. The biologically active principal was isolated and purified. Estimation of proteins, from the leaf samples of N.glutinosa plants, indicated higher concentration of new proteins in plants whose two basal leaves were treated 24 hours earlier with an aqueous solution of the glycoprotein. SDS-PAGE analysis studies on partially purified antiviral principal of protein nature revealed that the size of band in L3 (after 24 hours) was 30 Kda along with very dark and prominent bands. The size of band recorded in rest treatments was of 36 Kda and 50 Kda.
{"title":"Molecular Characterization of Antiviral Proteins, Isolated from Host Plants, Pretreated with Antiviral Glycoprotein, Isolated from Roots of Boerhaavia Diffusa Plants","authors":"Sharma Nk, Awasthi Lp","doi":"10.15406/JHVRV.2017.05.00156","DOIUrl":"https://doi.org/10.15406/JHVRV.2017.05.00156","url":null,"abstract":"Antiviral proteins were isolated, from host plants, following treatment with an antiviral glycoprotein, extracted from the roots of Boerhaavia diffusa plants. It was found to be active against isometric as well as an isometric viruses in their respective hypersensitive and systemic hosts. The biologically active principal was isolated and purified. Estimation of proteins, from the leaf samples of N.glutinosa plants, indicated higher concentration of new proteins in plants whose two basal leaves were treated 24 hours earlier with an aqueous solution of the glycoprotein. SDS-PAGE analysis studies on partially purified antiviral principal of protein nature revealed that the size of band in L3 (after 24 hours) was 30 Kda along with very dark and prominent bands. The size of band recorded in rest treatments was of 36 Kda and 50 Kda.","PeriodicalId":92670,"journal":{"name":"Journal of human virology & retrovirology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45348996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-04DOI: 10.15406/jhvrv.2017.05.00157
C. Gorham
{"title":"HIV the Best Thing to Happen to me","authors":"C. Gorham","doi":"10.15406/jhvrv.2017.05.00157","DOIUrl":"https://doi.org/10.15406/jhvrv.2017.05.00157","url":null,"abstract":"","PeriodicalId":92670,"journal":{"name":"Journal of human virology & retrovirology","volume":" ","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2017-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46719912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-04-03DOI: 10.15406/JHVRV.2017.05.00155
D. Bickel
{"title":"Equity, Land Tenure and HIV/AIDS - Opportunity and Risk in Namibian Agricultural Sector","authors":"D. Bickel","doi":"10.15406/JHVRV.2017.05.00155","DOIUrl":"https://doi.org/10.15406/JHVRV.2017.05.00155","url":null,"abstract":"","PeriodicalId":92670,"journal":{"name":"Journal of human virology & retrovirology","volume":"5 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2017-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41856720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-28DOI: 10.15406/jhvrv.2017.05.00153
S. Xueref, J. Holianjavony, H. Capart, R. Rakotoarisoa, M. Trabaud, D. Kerouedan, Raymond Daniel, P. Vanhems
{"title":"Prevalence and Risk Factors of HIV Infection, Syphilis, Genital Chlamydia and Viral Hepatitis B and C in a Pregnant Women’s Population of Southwest Madagascar","authors":"S. Xueref, J. Holianjavony, H. Capart, R. Rakotoarisoa, M. Trabaud, D. Kerouedan, Raymond Daniel, P. Vanhems","doi":"10.15406/jhvrv.2017.05.00153","DOIUrl":"https://doi.org/10.15406/jhvrv.2017.05.00153","url":null,"abstract":"","PeriodicalId":92670,"journal":{"name":"Journal of human virology & retrovirology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48494381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-28DOI: 10.15406/JHVRV.2017.05.00154
H. Ahmed, Mohmad Ahmad Babikir Ibraheem Beely, M. S. E. Aziz, F. Alshammari, Salaheldein G Elzaki, G. M. O. Elhussein, R. Salih, Bassam Ahmed Almutlaq, Abdullah D Alotaibi, M. Alturkstani
1Department of Pathology, College of Medicine, University of Hail, Saudi Arabia 2Department of Histopathology and Cytology, FMLS, University of Khartoum, Sudan 3Department of Medical Laboratory, Faculty of Medicine, University of Kordofan, Sudan 4Department of Histopathology and Cytology, Faculty of Medical Laboratory Science, Sudan University for Science and Technology, Sudan 5Department of Clinical Laboratory, College of Applied Medical Science, University of Hail, KSA, Saudi Arabia 6Department of epidemiology, Tropical Medicine Institute, Sudan 7Batterjee Medical College, KSA, Saudi Arabia
{"title":"Molecular Detection of High Risk Human Papilloma Viruses (HR-HPV 16 and 18) among Patients with Esophageal Cancer","authors":"H. Ahmed, Mohmad Ahmad Babikir Ibraheem Beely, M. S. E. Aziz, F. Alshammari, Salaheldein G Elzaki, G. M. O. Elhussein, R. Salih, Bassam Ahmed Almutlaq, Abdullah D Alotaibi, M. Alturkstani","doi":"10.15406/JHVRV.2017.05.00154","DOIUrl":"https://doi.org/10.15406/JHVRV.2017.05.00154","url":null,"abstract":"1Department of Pathology, College of Medicine, University of Hail, Saudi Arabia 2Department of Histopathology and Cytology, FMLS, University of Khartoum, Sudan 3Department of Medical Laboratory, Faculty of Medicine, University of Kordofan, Sudan 4Department of Histopathology and Cytology, Faculty of Medical Laboratory Science, Sudan University for Science and Technology, Sudan 5Department of Clinical Laboratory, College of Applied Medical Science, University of Hail, KSA, Saudi Arabia 6Department of epidemiology, Tropical Medicine Institute, Sudan 7Batterjee Medical College, KSA, Saudi Arabia","PeriodicalId":92670,"journal":{"name":"Journal of human virology & retrovirology","volume":" ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45818297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-20DOI: 10.15406/JHVRV.2017.05.00152
P. Koka
Maternal to child transmission (MTCT) of human immunodeficiency virus type 1 (HIV-1) infection has been greatly controlled by administration of anti-retroviral therapy (ART) [1]. We have reported that the sulfatide (3-O-galactosylceramide) promotes rescue of hematopoiesis in vivo [2]. Infection of human parainfluenza virus type 3 (hPIV3) has been shown to be inhibited by sulfatide (HSO3-3galactosylceramide) by other investigators [3]. Thus our earlier discussions on the importance of the different isoforms of and the seemingly differing types of biologically occurring sulfatides, lend credence to our proposed necessity of opposing (bi)directional investigations and their extent of beneficial or deleterious roles [4]. Further such varying functional roles emanating from the placental plasma membranes may well seal the fate of vertical transmission of each type of virus, in the absence of prenatal maternal treatments. This is more so when a temporary or permanent abstinence from sex is not practiced by the parents when aware of the diagnosed infections and thus the nature of virus persistence.
{"title":"Vertical Transmission of Virus Infections-Placenta as Facilitator or Inhibitor","authors":"P. Koka","doi":"10.15406/JHVRV.2017.05.00152","DOIUrl":"https://doi.org/10.15406/JHVRV.2017.05.00152","url":null,"abstract":"Maternal to child transmission (MTCT) of human immunodeficiency virus type 1 (HIV-1) infection has been greatly controlled by administration of anti-retroviral therapy (ART) [1]. We have reported that the sulfatide (3-O-galactosylceramide) promotes rescue of hematopoiesis in vivo [2]. Infection of human parainfluenza virus type 3 (hPIV3) has been shown to be inhibited by sulfatide (HSO3-3galactosylceramide) by other investigators [3]. Thus our earlier discussions on the importance of the different isoforms of and the seemingly differing types of biologically occurring sulfatides, lend credence to our proposed necessity of opposing (bi)directional investigations and their extent of beneficial or deleterious roles [4]. Further such varying functional roles emanating from the placental plasma membranes may well seal the fate of vertical transmission of each type of virus, in the absence of prenatal maternal treatments. This is more so when a temporary or permanent abstinence from sex is not practiced by the parents when aware of the diagnosed infections and thus the nature of virus persistence.","PeriodicalId":92670,"journal":{"name":"Journal of human virology & retrovirology","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41511562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-17DOI: 10.15406/JHVRV.2017.05.00150
Bogoyavlenskiy Ap
Submit Manuscript | http://medcraveonline.com population, as a carrier, and transporter of infectious diseases, as well as the evolutionary processes occurring in the population of the pathogen of the disease. Changes in climatic conditions can lead to the appearance of natural reservoir of new viral infections. For example, soft winter and spring conditions, heavy rainfall, as a rule, become a cause of a sharp increase in the number of rodents and mosquitoes, which in turn can lead to outbreaks of infectious diseases: the frequency of epizootic Rift Valley fever in Kenya, outbreaks of West Nile fever in the United States and Russia, the outbreak of infections caused by Hantavirus Sin Nombre and Bayu in the United States, hemorrhagic fever in the territory of Russia and Kazakhstan.
{"title":"Strategy of Control and Containment of Viral and other Infectious Diseases","authors":"Bogoyavlenskiy Ap","doi":"10.15406/JHVRV.2017.05.00150","DOIUrl":"https://doi.org/10.15406/JHVRV.2017.05.00150","url":null,"abstract":"Submit Manuscript | http://medcraveonline.com population, as a carrier, and transporter of infectious diseases, as well as the evolutionary processes occurring in the population of the pathogen of the disease. Changes in climatic conditions can lead to the appearance of natural reservoir of new viral infections. For example, soft winter and spring conditions, heavy rainfall, as a rule, become a cause of a sharp increase in the number of rodents and mosquitoes, which in turn can lead to outbreaks of infectious diseases: the frequency of epizootic Rift Valley fever in Kenya, outbreaks of West Nile fever in the United States and Russia, the outbreak of infections caused by Hantavirus Sin Nombre and Bayu in the United States, hemorrhagic fever in the territory of Russia and Kazakhstan.","PeriodicalId":92670,"journal":{"name":"Journal of human virology & retrovirology","volume":"5 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2017-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48694325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-17DOI: 10.15406/JHVRV.2017.05.00149
A. Alimohammadi, Geneviève Kerkerian, T. Raycraft, B. Conway
1.1.Introduction: HCV and HIV are global pandemics that affect 170 million and 35 million individuals, respectively. Up to 45% of individuals infected with HCV clear their infections spontaneously – correlating to factors like female sex, aboriginal descent, symptomatic acute hepatitis and some host specific immune factors. HIV, however, establishes true latency in infected cells, and therefore cannot be cured. In the setting of long-term non-progressors (LTNPs) of HIV, a state of immune preservation and low circulating viral load is established. Regarding HIV/HCV co- infection, little is known about the relationship between spontaneous clearance of HCV infection and long-term control of HIV infection without the benefit of antiretroviral therapy. 1.2.Case Presentation: We describe a case of a HIV-infected female who was an established LTNP in whom spontaneous clearance of HCV was documented on multiple occasions. 1.3.Conclusion: Similar cases of HIV LTNPs who may be exposed repeatedly to HCV and fail to establish productive infections should be documented and identified in an effort to develop novel hypotheses about natural control of both HIV and HCV. In the future, this could inform research on immune-based interventions to control these infections.
{"title":"Repeated Spontaneous Clearance of Hepatitis C Virus (HCV) Infection in the Setting of Long-Term Non-Progression of Human Immunodeficiency Virus (HIV) Infection","authors":"A. Alimohammadi, Geneviève Kerkerian, T. Raycraft, B. Conway","doi":"10.15406/JHVRV.2017.05.00149","DOIUrl":"https://doi.org/10.15406/JHVRV.2017.05.00149","url":null,"abstract":"1.1.Introduction: HCV and HIV are global pandemics that affect 170 million and 35 million individuals, respectively. Up to 45% of individuals infected with HCV clear their infections spontaneously – correlating to factors like female sex, aboriginal descent, symptomatic acute hepatitis and some host specific immune factors. HIV, however, establishes true latency in infected cells, and therefore cannot be cured. In the setting of long-term non-progressors (LTNPs) of HIV, a state of immune preservation and low circulating viral load is established. Regarding HIV/HCV co- infection, little is known about the relationship between spontaneous clearance of HCV infection and long-term control of HIV infection without the benefit of antiretroviral therapy. \u0000 \u0000 1.2.Case Presentation: We describe a case of a HIV-infected female who was an established LTNP in whom spontaneous clearance of HCV was documented on multiple occasions. \u0000 \u0000 1.3.Conclusion: Similar cases of HIV LTNPs who may be exposed repeatedly to HCV and fail to establish productive infections should be documented and identified in an effort to develop novel hypotheses about natural control of both HIV and HCV. In the future, this could inform research on immune-based interventions to control these infections.","PeriodicalId":92670,"journal":{"name":"Journal of human virology & retrovirology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44880075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-03-15DOI: 10.15406/JHVRV.2017.05.00148
Tai-Huang Huang
{"title":"Unraveling the Packaging Mechanism of Coronavirus Ribonucleocapsid","authors":"Tai-Huang Huang","doi":"10.15406/JHVRV.2017.05.00148","DOIUrl":"https://doi.org/10.15406/JHVRV.2017.05.00148","url":null,"abstract":"","PeriodicalId":92670,"journal":{"name":"Journal of human virology & retrovirology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49217669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}