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Cardiovascular Autonomic Functions and Its Association with Oxidative Stress Marker in Heavy Smoking and Smokeless Tobacco Users of Low Socioeconomic Status 重度吸烟和社会经济地位低下的无烟人群心血管自主功能及其与氧化应激标志物的关系
Pub Date : 2021-03-30 DOI: 10.37506/IJOP.V9I2.2914
R. Katuri, N. Prabhu, G. Pal
Background: Tobacco usage is a major preventable cause for cardiovascular morbidity and mortality.Tobacco is used in both smoking and smokeless forms. Alteration in cardiac autonomic function is amajor predisposing factor for cardiovascular risk. There are only limited studies available which assessedautonomic functional status in smokeless tobacco users. This study was aimed to assess and compare thecardiac autonomic activity and oxidative stress in smoking and smokeless tobacco users with controls.Methods: Sixty seven apparently healthy volunteers from the construction workers of low socioeconomicstatus were recruited. Those who are having habit of using tobacco in any form (n=42) were categorizedinto smoking tobacco group (n = 22) based on the smoking index and fagerstrom score for smokelesstobacco group (n = 20). Those who never used tobacco in any form were included as control group (n= 25).Cardiovascular autonomic function tests were performed and serum malondialdehyde was measured fromvenous blood sample.Conclusion: In this study we found that there is definite alteration in cardiac autonomic function which isin correlation with the level of oxidative stress in heavy tobacco users. This alteration is seen more in heavysmokeless tobacco users in compare with smoking tobacco users.
背景:吸烟是心血管疾病发病率和死亡率的主要可预防原因。烟草有吸烟和无烟两种形式。心脏自主神经功能的改变是心血管风险的主要诱发因素。只有有限的研究可以评估无烟烟草使用者的自主功能状态。本研究旨在评估和比较吸烟和无烟烟草使用者与对照组的心脏自主神经活动和氧化应激。方法:从社会经济地位低下的建筑工人中招募67名表面健康的志愿者。根据吸烟指数和无烟烟草组fagerstrom评分(n=20),将有任何形式吸烟习惯的人(n=42)分为吸烟烟草组(n=22)。从未使用过任何形式烟草的人被纳入对照组(n=25)。进行心血管自主功能测试,并从静脉血样中测量血清丙二醛。结论:在本研究中,我们发现重度烟草使用者的心脏自主神经功能存在一定的改变,这与氧化应激水平有关。与吸烟的烟草使用者相比,这种变化在体重减轻的烟草使用者中更为明显。
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引用次数: 0
Textile Workers and Musculoskeletal Disorders: An Anthropo- Medical Analysis 纺织工人与肌肉骨骼疾病:人类医学分析
Pub Date : 2021-03-30 DOI: 10.37506/IJOP.V9I2.2910
A. Jaiswal
Background: Musculoskeletal disorders are quite common work associated health problem amongsttextile workers. Work-related musculoskeletaldisorders are conditions in which: The work environment andperformance of work contribute significantly to the condition; and/or the condition is made worse or persistslonger due to working conditions, textile workers may be denied of their fundamental basic rightsand not muchimportance is given to their health. Textileworkers are among the maximumsusceptible as they must have towork for lengthy hoursor duration in perilous posture.Objectives: Present paper aims to study the anthropo-medical profile of textile workers especially in thecontext of musculoskeletal disorders among the textile workers.Methodology: A cross-sectional study was conducted among 215 workers working in textile industriesespecially silk sarees (Banarsi saress) of district Bhadohi, Uttar Pradesh over a period of more than threemonths. Data collection was done after taking the ethical clearance using a semi-structured interviewschedule and statistical analysis was done using SPSS.Results: The result of this study shows that there were 48.5 percent of respondents found to be sufferingfrom musculoskeletal disorders. The most common affected site was low back and shoulder. Most of theworkers experienced that their pain occurred occasionally during heavy workload.Conclusion: Hence, the musculoskeletal disorders were found to be associated in age group, sex andeducational status. So, Health problems among textile workers are one of the areas of public health concernin the country. Reducing the work strain and providing a supportive workplace environment will have afavorable impact on work productivity.
背景:肌肉骨骼障碍是纺织工人中常见的与工作相关的健康问题。与工作相关的肌肉骨骼损伤是指:工作环境和工作表现对这种情况有显著影响;和/或由于工作条件的原因,情况变得更糟或持续更长,纺织工人可能被剥夺基本权利,对他们的健康也没有太大的重视。短信工作者是最令人担忧的人群之一,因为他们必须以危险的姿势长时间或持续工作。目的:本文旨在研究纺织工人的人类医学概况,特别是纺织工人肌肉骨骼疾病的情况。方法:对215名纺织业工人进行了为期三个多月的横断面研究,特别是北方邦Bhadohi区的丝绸纱丽(Banarsi纱丽)。在获得伦理许可后,使用半结构化访谈表进行数据收集,并使用SPSS进行统计分析。结果:这项研究的结果显示,48.5%的受访者患有肌肉骨骼疾病。最常见的受影响部位是下背部和肩部。大多数工人都经历过在繁重的工作中偶尔会出现疼痛。结论:因此,发现肌肉骨骼疾病与年龄组、性别和教育状况有关。因此,纺织工人的健康问题是国家公共卫生关注的领域之一。减少工作压力和提供支持性的工作环境将对工作效率产生可避免的影响。
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引用次数: 0
Association Between Hypertension and ABO Blood Groups: A Prospective Study among Students 高血压与ABO血型的关系:一项对学生的前瞻性研究
Pub Date : 2021-03-30 DOI: 10.37506/ijop.v9i2.2912
P. Jha, Harsh Jha, A. Pathak
Background: High blood pressure (BP) is a major public health problem in India and its prevalence israpidly increasing among both urban and rural populations. Age, gender, genetic factors and ethnicity arenon-modifiable risk factors of hypertension. The ABO blood group is inherently heritable, geneticallydetected at time of conception and becomes permanent for whole life. This study intends to find out anyeffect of different blood groups on development of hypertension.Method : A total of 172 subjects were studied between March 2017 to June 2018. Blood pressure of all theparticipants in the study was recorded using mercury sphygmomanometer. The formula, weight in kg wasdivided by height in meter square was used to calculate the BMI of patients and unit is kg/m2. The datacollected was compiled and analysed using chi-square test. SPSS ver. 16 was used for this. P value of <0.005was considered highly significant.Conclusion: Blood group B has the highest tendency to be obese and developed both prehypertension andhypertension. Whereas blood group AB has least chance to develop hypertension and obesity.
背景:高血压(BP)是印度的一个主要公共卫生问题,其在城市和农村人口中的患病率都在迅速上升。年龄、性别、遗传因素和种族是不可改变的高血压危险因素。ABO血型是天生可遗传的,在受孕时进行基因检测,并在一生中永久存在。本研究旨在了解不同血型对高血压发展的影响。方法:2017年3月至2018年6月,共对172名受试者进行了研究。使用水银血压计记录研究中所有参与者的血压。采用体重(kg)除以身高(平方米)的公式计算患者的BMI,单位为kg/m2。使用卡方检验对收集的数据进行汇编和分析。采用SPSS第16版软件。P值<0.005被认为是高度显著的。结论:B血型的肥胖倾向最高,同时发生高血压前期和高血压。而AB血型患高血压和肥胖的几率最小。
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引用次数: 0
Perinatal Psychiatry in Context to Women ‘S Health 围产期精神病学与妇女健康的关系
Pub Date : 2021-03-30 DOI: 10.37506/IJOP.V9I2.2917
Suchi Pande, Ritu Srivastava, M. Srivastava
Introduction: Women’s Mental Health Traditionally focuses on women’s reproductive health,like Puberty,Pregnancy, Menopause now it is expanding to include disorders and conditions more prevalent in femalesthan in males, or different in clinical features and risk factors. Perinatal Psychiatry refers to mental healthissues in antenatal and postpartum period like Antenatal depression, Postnatal blues, Postpartum depression,Postpartum psychosis.Methods: The global burden of psychiatric disorders in women is increasing, especially in the perinatalperiod. We have focused on discussing the impact of culture on the perinatal psychiatric disorders andmanagement principles of different perinatal psychiatric disorders. Health?care delivery in the perinatalgroup of population has been improving over the years, but still there is lot to improve.Conclusion: A scientific and evidence?based approach is a definite need toward attaining this goal.
导论:妇女心理健康传统上侧重于妇女的生殖健康,如青春期、妊娠期、更年期,现在它正在扩大到包括女性比男性更普遍的疾病和状况,或在临床特征和风险因素上不同。围产期精神病学是指产前和产后出现的心理健康问题,如产前抑郁、产后忧郁、产后抑郁、产后精神病等。方法:全球妇女精神疾病负担正在增加,特别是在围产期。我们着重讨论了文化对围产期精神障碍的影响以及不同围产期精神障碍的处理原则。健康吗?围产期人群的护理服务多年来一直在改善,但仍有很多需要改进的地方。结论:科学和证据?基于的方法是实现这一目标的明确需要。
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引用次数: 0
Study of the Lung Function Tests in Healthy Non-Smoking Women Using Different Cooking Fuels 健康非吸烟女性使用不同烹饪燃料的肺功能测试研究
Pub Date : 2021-03-30 DOI: 10.37506/IJOP.V9I2.2911
Archana Singh, Namita, Rinku Garg, M. Gupta
Background: In developing country like India still a large group of women use biomass as the cookingfuel in a poorly ventilated cooking area and it is considered as a major risk factor for respiratory diseases.Throughthis study we sought to find the effect of biomass and LPG fuel use on the lung function by studspirometry.Method: This cross-sectional study was conducted in the rural and urban areas of Ghaziabad. We assessedthe lung function in 100 non-smoker females (50 biomass and 50 LPG fuel users) and studies the presenceof any correlation between lung function and the duration of exposure.Results: Compared to LPG users biomass fuel users had significantly lower values of FVC (p = 0.007), FEV1(p = 0.0024), FEV1/FVC (p <0.0001) and PEFR (p = 0.007). Statistically significant negative correlationwas also found between exposure index and spirometry values in both the groups.Conclusion: Biomass fuel has a more adverse effect on the lung function and the lung function decline isassociated with the exposure duration.
背景:在像印度这样的发展中国家,仍然有一大群妇女在通风不良的烹饪区使用生物质作为烹饪燃料,这被认为是患呼吸道疾病的主要风险因素。通过这项研究,我们试图通过研究比色法来发现生物质和液化石油气燃料的使用对肺功能的影响。方法:这项横断面研究在加齐阿巴德的农村和城市地区进行。我们评估了100名不吸烟女性(50名生物质和50名液化石油气燃料使用者)的肺功能,并研究了肺功能与暴露时间之间的相关性。结果:与液化石油气用户相比,生物质燃料用户的FVC(p=0.007)、FEV1(p=0.0024)、FEV1/FVC(p<0.0001)和PEFR(p=0.007)显著降低。两组的暴露指数和肺活量测定值之间也存在统计学上显著的负相关。结论:生物质燃料对肺功能的影响较大,肺功能下降与暴露时间有关。
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引用次数: 1
The Effect of Trataka Yoga Kriya on Visual Evoked Potential In Myopes Trataka瑜伽Kriya对近视眼视觉诱发电位的影响
Pub Date : 2021-03-30 DOI: 10.37506/IJOP.V9I2.2923
S. Sushma, U. Dixit
Aim of Study: To evaluate the effects of Trataka yoga on Visual Evoked Potential (VEP) in myopic subjectsMethodology: Out of 36 myopes recruited for the study, 25 subjects were considered for statistical analysis.Visual Evoked Potential was recorded before and after an intervention of Trataka yoga kriya for 3 weeks.Results: The study showed that there was no significant statistical change in P100 latency pre and postintervention with mean readings of 95.25 and 95.79ms pre and post intervention respectively for the left eyeand 95.15 and 96.4ms pre and post intervention respectively for right eye.Conclusion: Our study concluded that Trataka yoga has no significant effect on VEP but better designedstudies need to be done on a larger sample to confirm these findings and study the above associationaccurately.
研究目的:评估Trataka瑜伽对近视受试者视觉诱发电位(VEP)的影响。方法:在本研究招募的36名近视患者中,考虑25名受试者进行统计分析。在Trataka瑜伽kriya干预前后记录视觉诱发电位3周。结果:干预前后P100潜伏期无显著统计学变化,干预前后左眼P100潜伏期平均值分别为95.25和95.79ms,干预前后右眼P100潜伏期分别为95.15和96.4ms。结论:我们的研究得出结论,Trataka瑜伽对VEP没有显著影响,但需要在更大的样本上进行更好的设计研究,以证实这些发现,并准确地研究上述相关性。
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引用次数: 0
A Study of Incidence of Pre-Eclampsia in Relation to Maternal Age 先兆子痫发病率与产妇年龄关系的研究
Pub Date : 2021-03-30 DOI: 10.37506/IJOP.V9I2.2913
Ranjana Dhar
Background: - Pre-eclampsia is a serious complication of pregnancy and contributes significantly maternalas well as perinatal morbidity and mortality. So this study is done to find if there exists any relationshipbetween maternal age and pre-eclampsia.Aim:- To study what age group is more prone to development of pre-eclampsia in normal pregnancies.Methodology:- 400 pre-eclamptic women in age group 18-42 years were included in the study. Cases aredivided according to different age group.Result:- Higher incidence of pre-eclampsia was observed in the age group 18-26 years followed by 35-42years.Discussion:- Age is found to be related to pre-eclampsia.Conclusion:- From this study, this can be concluded that age less than 25 years and age greater than 35 yearsare more prone to development of pre-eclampsia.
背景:先兆子痫是一种严重的妊娠并发症,对产妇和围产儿的发病率和死亡率有重要影响。所以这项研究是为了发现母亲的年龄和先兆子痫之间是否存在联系。目的:研究正常妊娠中哪个年龄组更容易发生先兆子痫。方法:400名年龄在18-42岁的先兆子痫妇女纳入研究。病例根据不同年龄组划分。结果:先兆子痫发生率以18 ~ 26岁年龄组最高,其次为35 ~ 42岁年龄组。讨论:年龄被发现与子痫前期有关。结论:从这项研究中可以得出,年龄小于25岁和大于35岁的人更容易发生先兆子痫。
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引用次数: 0
Effect of Caffeine on Multi-domain Neurocognitive Abilities in Occasional Coffee Consumers 咖啡因对咖啡消费者多领域神经认知能力的影响
Pub Date : 2021-03-30 DOI: 10.37506/IJOP.V9I2.2915
P. Sasikala, A. V. S. Kumar, K. Maruthy, John Preetham . Gurja
Background: Multi-domain neurocognitive abilities underpin timely perception & appropriate action tounexpected threats in the dynamic environment. Hence enhancement of the same may be life-saving in somesituations. Caffeine is the most widely consumed CNS stimulant which not only enhances neurocognitiveabilities but also temporarily counteracts neurocognitive deficits. Therefore this study has been undertakento quantify the effect of Caffeine on Multi-domain neurocognitive skills.Aim: To find out the effect of Caffeine on neurocognitive abilities in occasional coffee consumersMaterials & Methods: This study was conducted on 23 participants. In all the subjects under basalconditions, a battery of multi-domain neurocognitive tests, which included ART, VRT, CFFF, Digits forwardtests were conducted. Then a standard dose of 2.2grams of instant coffee powder (Nestle – 69.6mg ofCaffeine) dissolved in 100 ml of milk was given. After 30 minutes of intake, the same battery of tests wasrepeated, and the test results were analyzed.Results: In our study, we have found that Caffeine significantly increases CFFF (p<0.001), Digits forwardtest score (p<0.001) and decreases VRT (p=0.03). It also reduces ART, but it is not statistically significant.(p=0.06).Conclusion: Caffeine significantly improves Critical flicker fusion frequency, attention span, performanceand reduces reaction time.
背景:多领域神经认知能力是在动态环境中及时感知和采取适当行动应对预期威胁的基础。因此,在某些情况下,增强同样的功能可能会挽救生命。咖啡因是消费最广泛的中枢神经系统兴奋剂,它不仅能增强神经认知能力,还能暂时抵消神经认知缺陷。因此,本研究旨在量化咖啡因对多领域神经认知技能的影响。目的:了解咖啡因对偶尔喝咖啡的人神经认知能力的影响材料与方法:本研究对23名参与者进行。在基础条件下的所有受试者中,进行了一系列多领域神经认知测试,包括ART、VRT、CFFF、Digits正向测试。然后给予标准剂量的2.2克速溶咖啡粉(雀巢69.6毫克咖啡因),溶解在100毫升牛奶中。摄入30分钟后,重复相同的一组测试,并对测试结果进行分析。结果:在我们的研究中,我们发现咖啡因显著增加了CFFF(p<0.001)、Digits正向测试得分(p<001)和降低了VRT(p=0.03)。它也降低了ART,但没有统计学意义。(p=0.06)。结论:咖啡因显著提高临界闪烁融合频率、注意力持续时间、表现能力并缩短反应时间。
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引用次数: 0
Changes in the Polysomnographic Measures in Patients of Chronic Insomnia on Drug Therapy Vs Mindful Awareness 药物治疗与正念意识对慢性失眠症患者多导睡眠测量的影响
Pub Date : 2021-01-27 DOI: 10.37506/IJOP.V9I1.2610
Shweta Kanchan, Basu Dev Singh, G. Swaroop, G. Kumar
Background:- Modern day 24*7 lifestyle is witnessing an increase in people with insomnia like neverbefore. The deep and restoring sleep like a baby seems to have vanished from our hectic lifestyles ,andsleep disorders like insomnia have crept in involving people across all ages and sections of society. In thegiven scenario it remains a matter of concern that most primary physicians are not trained in the variousmodalities which could be used for the treatment of insomnia. In the absence of required knowledge ininsomnia management hypnotic medication remain the preferred treatment for insomnia . The present studywas undertaken with a view to study the effectiveness of mindfulness based relaxation therapy vs hypnoticmedication for the treatment of insomnia.Methods :- A cross sectional study was conducted on 100 patients suffering from insomnia in two groups,pharmacotherapy (PCT) group and Mindfulness based stress reduction (MBSR) group. MBSR a programof mindfulness meditation training consisting of one hour long class daily which includes training inprogressive muscular exercises, breathing exercises, standing, sitting and walking meditations. Homepractice expectations were 30 minutes of medication per day and following an attitude of mindfulnessthrough out the day during the four week follow.Result :- The study showed comparable results on all sleep parameters for both groups. There was asignificant increase in total sleep time in both groups, the increase was more with drug group compare tothe MBSR group.Conclusion :- While the time commitment associated with participating in and practicing a behavioralintervention such as MBSR is more than with medication, our results suggest that this is not a deterrent tomost of our participants. Given patient preferences, the side effects of pharmacotherapy, evidence of theefficacy of MBSR and the potential positive benefits of meditation that go beyond management of insomniasymptoms.
背景:现代24*7的生活方式见证了失眠患者前所未有的增加。像婴儿一样的深度睡眠和恢复性睡眠似乎已经从我们繁忙的生活方式中消失了,失眠等睡眠障碍已经蔓延到各个年龄段和社会阶层。在这种情况下,大多数初级医生没有接受过治疗失眠的各种方法的培训,这仍然是一个令人担忧的问题。在缺乏失眠管理所需知识的情况下,催眠药物仍然是失眠的首选治疗方法。本研究旨在研究基于正念的放松疗法与催眠疗法治疗失眠的有效性。方法:对100例失眠患者进行横断面研究,分为药物治疗组和正念减压组。MBSR是一项正念冥想训练计划,包括每天一小时的课程,包括渐进式肌肉锻炼、呼吸锻炼、站立、坐着和行走冥想的训练。家庭实践的期望是每天服用30分钟的药物,并在接下来的四周里保持一整天的专注态度。结果:-研究显示,两组患者的所有睡眠参数具有可比性。两组患者的总睡眠时间均显著增加,与MBSR组相比,药物组的增加幅度更大。结论:-虽然参与和实践行为干预(如MBSR)的时间承诺比药物更重要,但我们的研究结果表明,这对大多数参与者来说并不是一种威慑。考虑到患者的偏好、药物治疗的副作用、MBSR有效性的证据以及冥想的潜在积极益处,这些都超出了失眠症状的管理范围。
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引用次数: 0
Hypothyroid Patients with Positive Thyroid Antibodies and Relation to Nerve Conduction Study Findings 甲状腺功能减退患者甲状腺抗体阳性与神经传导关系的研究结果
Pub Date : 2021-01-27 DOI: 10.37506/IJOP.V9I1.2605
I. V. Padma, S. Panda
Neuropathies are common manifestations of more than half the patients attending medical out patientdepartments . These neuropathies could be due to many causes. Some of the patients are not diabeticsor alcoholics and thyroid profile revealed hypothyroidism . Most of the patients were not on thyroidsupplementation and some are on irregular treatment. Primary symptoms are vague not pointing to eitherthyroid deficiency or diabetes mellitus complained of lethargy , pain in the fingers stabbing in nature ,wightgain, dryskin ,constipation . Nerve conduction studies on median and ulnar nerves in these patients withoutdiabetes and other deficiency disorders point to miss hypothyroid state in these patients, as stress is put ondiagnosing more common conditions like diabetes mellitus. If these conditions are excluded it is not difficultto diagnose hypothyroid conditions.
神经病变是一半以上的门诊病人的常见表现。这些神经病变可能是由许多原因引起的。部分患者并非糖尿病或酗酒者,甲状腺检查显示甲状腺功能减退。多数患者未进行甲状腺补充治疗,部分患者接受不规律治疗。主要症状不明确,不能说明甲状腺功能不全或糖尿病,有嗜睡、手指刺痛、体重增加、皮肤干燥、便秘。在这些没有糖尿病和其他缺乏性疾病的患者中,对正中神经和尺神经的神经传导研究表明,由于强调诊断更常见的疾病,如糖尿病,这些患者的甲状腺功能低下状态被忽略了。如果排除这些情况,诊断甲状腺功能减退并不困难。
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引用次数: 0
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International journal of physiology
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