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Study of Cardiovascular Parameters and Heart Rate Variability (Frequency Domain Analysis) in 1St Trimester of Normal Pregnant Women and Pregnant Women with Risk Factors for PIH in Western Rajasthan 拉贾斯坦邦西部正常孕妇和有妊高征危险因素孕妇妊娠早期心血管参数和心率变异性(频域分析)研究
Pub Date : 2021-08-27 DOI: 10.37506/ijop.v9i4.3170
Soniya Vyas, Raghuveer Choudhary, K. Choudhary, I. Khan
Background: The role of sympathovagal imbalance (SVI) and CV risk in pregnancy-inducedhypertension (PIH) has been reported, and their association during early trimesters of gestation in PIHhas not been studied. Therefore, in the present study, we have investigated the maternal cardiovascularparameters and frequency domain indices of Heart rate variability (HRV) between normal pregnantwomen and women with risk factors for PIH in their 1st trimester of gestation.Methods: Two hundred twenty subjects each (220 of normotensive pregnant women i.e., control groupand 220 of pregnant women with risk factor for PIH i.e., study group) of 1st trimester of gestation wererecruited from the obstetrics & gynecology department of Umaid hospital, associated with Dr. S. N.Medical College, Jodhpur, Rajasthan. Physical examination was done and anthropometric measurementlike height & weight were taken. The collected data was statistically analyzed using HRV analysissoftware.Results: Significant difference in body mass index was observed between the two groups. Systolic bloodpressure, Diastolic blood pressure, Pulse pressure, Rate pressure product and Mean arterial pressure ofstudy group was significantly higher than control group. Values of LF and LF/HF ratio components offrequency domain analysis of HRV were significantly increased but HF component is non significantlydecrease in 1st trimester of the pregnant women with risk factor for PIH than normal pregnant women.Conclusion: The present study indicates that the cardiovascular parameters in 1st trimester of pregnantwomen with risk factor for PIH were increased highly significantly than the normal pregnant women.The highly significant (HS) (p<0.000) increase in the LF (nu) & LF/HF ratio and non significant (NS)(p<0.552) decrease in HF (nu) of pregnant women with risk factors for PIH was observed than normalpregnant women this indicate that sympathetic tone was increased in 1st trimester of pregnant womenwith risk factor for PIH. Vagal withdrawal and sympathetic exaggeration may be the possible cause ofPIH in pregnant women with its risk factors.
背景:交感神经迷走神经失衡(SVI)和CV风险在妊娠高血压(PIH)中的作用已有报道,但尚未研究它们在妊娠早期与PIH的关系。因此,在本研究中,我们研究了妊娠前三个月正常孕妇和有妊高征危险因素妇女的母体心血管参数和心率变异性(HRV)的频域指数。方法:从拉贾斯坦邦Jodhpur S. n.医学院附属Umaid医院妇产科招募妊娠早期血压正常的孕妇各220例(对照组220例,有妊高征危险因素的孕妇220例,研究组220例)。进行体格检查和身高、体重等人体测量。采用HRV分析软件对收集的数据进行统计学分析。结果:两组患者体重指数差异有统计学意义。研究组收缩压、舒张压、脉压、率压积、平均动脉压均显著高于对照组。妊高征危险因素孕妇HRV频域分析中LF和LF/HF比值分量值较正常孕妇显著升高,HF分量值无显著降低。结论:本研究提示妊高征危险因素孕妇妊娠早期心血管指标明显高于正常孕妇。伴有妊高征危险因素孕妇的LF (nu)和LF/HF比值显著(HS) (p<0.000)升高,HF (nu)无显著(NS)(p<0.552)降低,提示妊高征危险因素孕妇在妊娠早期交感神经张力增高。迷走神经退缩和交感神经夸张可能是孕妇妊高征的可能原因及其危险因素。
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引用次数: 0
Depression, Anxiety and Stress Scores Inmale and Female Students 男女学生的抑郁、焦虑和压力得分
Pub Date : 2021-08-27 DOI: 10.37506/ijop.v9i4.3089
S. Bandaru, S. Goothy
Psychological parameters play a key role in the daily life of young adults.It was reported that there wasa high incidence of suicidal rate in these age groups when compared with others. The present study wasundertaken to observe the selected psychological parameters that are depression, anxiety, and stress in youngadults. A total of 50 (males =25, females =25) young adults studying undergraduate allied health coursesboth males and females were part of the study after obtaining the written informed consent. The followingcriterion was used to recruit the participants. Depression, anxiety, and stress levels were assessed using theDASS-42 questionnaire. Depression scores were significantly higher in females when compared with males.Anxiety and stress scores were not significantly different among males and females. Females were in severedepression where males were moderate. Anxiety scores of males and females were mild. Stress scores ofmales and females were severe. The study results support earlier studies and emphasize the need to assesspsychological parameters in young adults. The study also recommends detailed studies in this area.
心理参数在年轻人的日常生活中起着关键作用。据报道,与其他年龄组相比,这些年龄组的自杀率较高。本研究旨在观察年轻人的抑郁、焦虑和压力等心理参数。在获得书面知情同意书后,共有50名(男25名,女25名)学习本科联合健康课程的年轻人(男女均有)参与了研究。采用以下标准招募参与者。使用das -42问卷评估抑郁、焦虑和压力水平。女性的抑郁得分明显高于男性。焦虑和压力得分在男女之间无显著差异。女性处于严重抑郁状态,男性处于中度抑郁状态。男性和女性的焦虑得分都很轻微。男性和女性的压力得分都很严重。该研究结果支持了早期的研究,并强调了评估年轻人心理参数的必要性。该研究还建议在这一领域进行详细的研究。
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引用次数: 0
Cognition and Quality of Life in Patients with Type-2 Diabetes 2型糖尿病患者的认知和生活质量
Pub Date : 2021-07-08 DOI: 10.37506/ijop.v9i3.3068
P. Krishna
The present study was undertaken to observe the cognition and quality of life in type-2 diabetic patients. Thestudy included thirty type 2 diabetic patients and thirty age and gender matched healthy participants. Thefollowing criteria were used in the selection of cases. Spatial and verbal memory test was used to assess thecognition functions of the participants. Quality of life was assessed by using WHOQOL-BREF questionnairewhich is standardized questionnaire by World Health Organization. There was significant decrease in thespatial memory scores in the diabetic participants when compared with healthy individuals (P<0.001). Verbalmemory scores in the cases were significantly lower in the diabetic participants when compared with healthyindividuals (P<0.01). The four domains of the quality of life that is physical health, psychological, socialrelationships and environmental scores were significantly lower in the diabetic participants when comparedwith healthy individuals (P<0.001).There was a significant decrease in the cognitive functions and qualityof lifein the patients with type 2 diabetes when compared with healthy individuals. We recommend furtherdetailed studies in this area to plan and develop better management methods for the benefit of diabeticpopulation.
本研究旨在观察2型糖尿病患者的认知和生活质量。该研究包括30名2型糖尿病患者和30名年龄和性别匹配的健康参与者。病例选择采用以下标准。空间和语言记忆测试被用来评估参与者的认知功能。采用世界卫生组织标准化问卷WHOQOL-BREF对患者的生活质量进行评估。与健康个体相比,糖尿病参与者的空间记忆得分显著降低(P<0.001)。与健康个体比较,糖尿病参与者在病例中的言语记忆得分显著较低(P<0.01),糖尿病患者的社会关系和环境得分显著低于健康人(P<0.001)。2型糖尿病患者的认知功能和生活质量明显低于健康人。我们建议在这一领域进行进一步的详细研究,以规划和开发更好的管理方法,造福糖尿病人群。
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引用次数: 0
Effect of Perceived Stress on the Differential Leucocyte Count among Young Adults 感知应激对青年人白细胞计数差异的影响
Pub Date : 2021-07-08 DOI: 10.37506/ijop.v9i3.3063
Anindita Mahanta, C. Baruah
Exposure to any form of stress causes an increase in ACTH secretion by the anterior pituitary, followedby increased secretion of Cortisol, which decreases eosinophils, basophils and lymphocytes in blood andincreases the number of neutrophils.With the above background, the present study was carried out todetermine the changes brought on by perceived stress in the leukocyte profile of young adults.37 healthy,young adults participated in the study. Perceived stress was measured using the 10-item Perceived StressScale (PSS-10) and leukocyte profile was studied by performing a differential leukocyte count.A positivecorrelation was found between PSS score and percentage of neutrophils, monocytes and N:L ratio. A negativecorrelation was found between PSS score and percentage of lymphocytes, eosinophils and basophils.Stressidentification and management is an important component in the welfare of young adults. Differential countof leukocytes can provide a reliable method to study the response to stress.
暴露于任何形式的压力会导致垂体前叶ACTH分泌增加,随后皮质醇分泌增加,从而减少血液中的嗜酸性粒细胞、嗜碱性粒细胞和淋巴细胞,增加中性粒细胞的数量。在上述背景下,本研究旨在确定感知压力对年轻人白细胞谱带来的变化。37名健康的年轻人参加了这项研究。感知压力使用10项感知压力量表(PSS-10)测量,白细胞谱通过进行白细胞计数进行研究。PSS评分与中性粒细胞百分比、单核细胞百分比和N:L比值呈正相关。PSS评分与淋巴细胞、嗜酸性粒细胞和嗜碱性粒细胞百分比呈负相关。压力识别和管理是年轻人福利的重要组成部分。白细胞差异计数为研究应激反应提供了可靠的方法。
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引用次数: 0
A cross-sectional Study of Metamemory in Obese South Indian Females 南印度肥胖女性元记忆的横断面研究
Pub Date : 2021-07-08 DOI: 10.37506/ijop.v9i3.3065
G.Geethika, A.Sangeetha, M. Kumaresan, C. Hemachandrika, M. Karthika
Introduction: Metamemory is the introspective knowledge of one’s brain memory capability and process involved in memory self-monitoring. This self-awareness of memory has important implications for how people learn and use memories for everyday activities. Aim: The aim is to assess metamemory in female obese individuals. Materials and Method: A study was conducted among 165 female overweight and obese category at random south Indian population. The participants were asked to complete a self-reported questionnaire on metamemory. The Multifactorial Memory Questionnaire (MMQ) was developed to assess separate dimensions of memory ratings that are applicable to clinical assessment and intervention, includes scales of Contentment (i.e., affect regarding one’s memory), Ability (i.e., self-appraisal of one’s memory capabilities), and Strategy (i.e., reported frequency of memory strategy used). Result: Association between corresponding subscale scores and blood glucose which indicates a weak correlation between blood glucose, satisfaction ( r = -.008) and strategy ( r = -.07). In addition, the MMQ subscales and the total score showed good internal consistency (αs = 0.82-0.85). Conclusion: Obese and overweight female individuals had poor metamemory scores. The study would help the obese individuals to identify any early stage of cognitive impairment and create an awareness to delay or prevent any further metacognitive dysfunction.
引言:元记忆是对一个人大脑记忆能力和记忆自我监控过程的内省性认识。这种记忆的自我意识对人们如何在日常活动中学习和使用记忆具有重要意义。目的:目的是评估女性肥胖个体的元记忆。材料和方法:在165名超重和肥胖女性中随机抽取南印度人群进行研究。参与者被要求完成一份关于元记忆的自我报告问卷。开发多因素记忆问卷(MMQ)是为了评估适用于临床评估和干预的记忆评级的不同维度,包括满足感(即对记忆的影响)、能力(即对自己记忆能力的自我评估)和策略(即使用记忆策略的报告频率)。结果:相应的分量表得分与血糖之间存在相关性,表明血糖、满意度(r=-0.008)和策略(r=-0.07)之间的相关性较弱。此外,MMQ分量表与总分显示出良好的内部一致性(αs=0.82-0.85)。结论:肥胖和超重女性的元记忆得分较差。这项研究将帮助肥胖者识别认知障碍的早期阶段,并提高他们的意识,以延缓或预防任何进一步的元认知功能障碍。
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引用次数: 0
A Simple Model to Demonstrate the Critical Flicker Fusion Frequency Using Microsoft Office Powerpoint 用microsoftofficepowerpoint演示关键闪烁融合频率的简单模型
Pub Date : 2021-07-08 DOI: 10.37506/ijop.v9i3.3066
Kamalakannan Vadivel, N. Kate
Background: The critical flicker fusion frequency (CFF) is the frequency at which a flickering light isperceived as a continuous light. It is an index of visual temporal processing. It is affected in several diseaseconditions like hepatic encephalopathy, multiple sclerosis, age related macular degeneration and cataract.We wanted to demonstrate the phenomenon to undergraduate medical and health science students to helpthem understand the concept using a personal computer with Microsoft office power point suite.Aim: The aim of the study was to demonstrate this concept of CFF using a personal computer with Microsoftoffice power point suite in small groups to undergraduate medical and health science students and to take asurvey from the students regarding the demonstration and its outcome in understanding the concept of CFF.Material and Methods: It is a cross sectional survey obtained from the medical, dental and allied healthscience students following the demonstration of CFF using the personal computer with Microsoft officepower point suite in small groups.Results: Our results have shown that the demonstration have helped 94% of the students in understandingthe concept of the CFF. 91% of the students felt that the demonstration has helped them in reviewingthe topic.98% of the students felt that they would recommend the demonstration to future batches of thestudents. 86% of the students said that the demonstrations made the learning fun and exciting.Conclusions: The demonstration of CFF using the Microsoft office power point suite have helped thestudents to understand the concept evoking interest and enthusiasm as they were able to relate the conceptby demonstration and seeing it for themselves.
背景:临界闪烁融合频率(CFF)是闪烁光被感知为连续光的频率。它是视觉时间处理的一个指标。它会影响许多疾病,如肝性脑病、多发性硬化症、年龄相关性黄斑变性和白内障。我们希望向医学和健康科学专业的本科生演示这一现象,帮助他们使用带有微软office powerpoint套件的个人电脑理解这一概念。目的:本研究的目的是在小组中使用带有Microsoftoffice power point套件的个人计算机向医学和健康科学本科学生演示CFF的概念,并就演示及其在理解CFF概念方面的结果向学生进行调查。材料和方法:这是一项横断面调查,调查对象是医学、牙科和相关健康科学专业的学生,他们在小组中使用个人电脑和微软office powerpoint套件演示CFF。结果:我们的结果表明,演示帮助94%的学生理解了CFF的概念。91%的学生认为演示对他们复习主题有帮助。98%的学生认为他们会向未来的学生推荐演示。86%的学生表示演示使学习变得有趣和令人兴奋。结论:使用微软office powerpoint套件演示CFF,帮助学生理解概念,唤起兴趣和热情,因为他们能够将概念演示联系起来,并亲眼看到它。
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引用次数: 0
Association of Anaemia with Helicobacter Pylori in Adult Patients in a Tertiary Care Hospital 三级医院成人患者贫血与幽门螺杆菌的关系
Pub Date : 2021-07-08 DOI: 10.37506/ijop.v9i3.3067
M. Rastogi, Dolly Rastogi
Helicobacter pylori has been established as a major cause of various gastro-intestinal diseases like chronicgastritis and peptic ulcers as well as various extra gastrointestinal diseases such as anaemia. The presentcross - sectional study was done in the department of Medicine at G.S.V.M Medical College, Kanpur. A totalof 194 adult patients attending outpatient department for various gastrointestinal symptoms were screenedfor Helicobacter pylori using Stool antigen card test. Out of these 194 patients, 98 were found positive forHelicobacter pylori by the test, giving a prevalence of 50.51%. A detailed proforma was filled regarding theage and sex of the patient, education and occupation of the head of the family, sanitary practices and dietaryhabits. The patients were also examined for pallor and their complete blood count was done. Out of totalsubjects 77 were found to be suffering from anaemia from which 48 were H. pylori positive (62.3%). Apossible association can be established among patients suffering from H. Pylori infection and simultaneouslydiagnosed as anaemic
幽门螺杆菌已被确定为各种胃肠道疾病(如慢性胃炎和消化性溃疡)以及各种额外胃肠道疾病(如贫血)的主要原因。本横断面研究是在坎普尔G.S.V.M医学院医学系进行的。采用粪便抗原卡试验对194例因各种胃肠道症状就诊的门诊成年患者进行幽门螺杆菌筛查。194例患者中,98例检测幽门螺杆菌阳性,患病率为50.51%。填写了一份详细的表格,包括病人的年龄和性别、户主的教育和职业、卫生习惯和饮食习惯。还检查了患者的苍白和他们的全血细胞计数。其中77例贫血,48例幽门螺杆菌阳性(62.3%)。在患有幽门螺杆菌感染并同时被诊断为贫血的患者中,可能存在关联
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引用次数: 0
Sleep Quality and Day Time Sleepiness in Patients with Type-2 Diabetes 2型糖尿病患者的睡眠质量和日间嗜睡
Pub Date : 2021-07-08 DOI: 10.37506/ijop.v9i3.3069
P. Krishna
The present study was undertaken to observe the sleep quality and day time sleepiness in patients with type-2 diabetes. The study included thirty type 2 diabetic patients and thirty age and gender matched healthyparticipants. Pittsburgh Sleep Quality index (PSQI) was used to assess the sleep quality of the participants.Epworth sleepiness scale was used to assess the day time sleepiness. There was significantly lower sleepquality in the diabetic patients when compared with the healthy individuals (P<0.001). There was significantlyhigher day time sleepiness in the diabetic patients when compared with the healthy individuals (P<0.001).The study results suggest that there was a significant deterioration of sleep quality in diabetic individualswhich is reflected in day time sleepiness scores as diabetic individuals have higher day time sleepiness.We recommend further detailed studies to understand the association and also to develop better treatmentstrategies for the benefit of population in general.
本研究旨在观察2型糖尿病患者的睡眠质量和白天嗜睡情况。该研究包括30名2型糖尿病患者和30名年龄和性别匹配的健康参与者。匹兹堡睡眠质量指数(PSQI)用于评估参与者的睡眠质量。Epworth嗜睡量表用于评估白天的嗜睡程度。与健康人相比,糖尿病患者的睡眠质量显著降低(P<0.001)。与健康人比较,糖尿病患者白天嗜睡程度显著升高(P<0.01)。研究结果表明,糖尿病患者睡眠质量显著恶化,这反映在白天嗜睡得分是因为糖尿病患者白天嗜睡程度较高。我们建议进行进一步的详细研究,以了解这种关联,并制定更好的治疗策略,造福于广大人群。
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引用次数: 0
A Comparative Study of Maximum Voluntary Ventilation in Overweight & Obese Adult Males 超重与肥胖成年男性最大自主通气量的比较研究
Pub Date : 2021-07-08 DOI: 10.37506/ijop.v9i3.3064
D. Harsh, Raghuveer Choudhary
Introduction : Obesity is a global ep idemic. It is characterized by excessive fat accumulation in the body, which affects multiple organs including the respiratory system by various mechanisms. The Prevalence and severity of obesity in young adults is increasing worldwide. The lung functions can be measured by spirometry. The Maximum Voluntary Ventilation test evaluates the respiratory endurance and is influenced by the lung and chest compliance, control of breathing and airway resistance. Aim : The purpose of this study was to compare the Maximum Voluntary Ventilation parameter in obese, overweight and non-obese adult males and to evaluate the impact of obesity on MVV. Methodology: A cross-sectional study was conducted among seventy-six adult males of Western Rajasthan in the age group ranging 18-25 years were performed on a spirometer, who were further divided into three groups based on Body Mass Index (criteria for Asian Indians) two groups based on WHR (waist-hip ratio). The observed data were statistically analyzed using ANOVA, Post-Hoc test and Linear Regression test. Results: In our study , we found a significant reduction in MVV values in overweight and obese. The obese males had MVV (L/Min) of 68 ± 10.80; overweight males of 78.77 ± 17.93 whereas corresponding values in non-obese were 112.61 ± 19.42. According to ANOVA, a highly-significant (HS) difference among the three groups (p˂0.01) . The multiple regression method reveals a negative correlation with MVV which is highly-significant (p<0.01) . Conclusion: Our study concluded that the impairment of Pulmonary Function is strongly associated with adult overweight and obese males. The reduction in BMI by reducing weight can reduce morbidity.
引言:肥胖是全球性的流行病。它的特点是体内脂肪堆积过多,通过各种机制影响包括呼吸系统在内的多个器官。全世界年轻人肥胖的患病率和严重程度都在增加。肺功能可以通过肺活量测定法来测定。最大自主通气测试评估呼吸耐力,并受肺部和胸部顺应性、呼吸控制和气道阻力的影响。目的:本研究的目的是比较肥胖、超重和非肥胖成年男性的最大自主通气参数,并评估肥胖对MVV的影响。方法:对拉贾斯坦邦西部年龄段18-25岁的76名成年男性进行了一项横断面研究,他们使用肺活量计进行了测量,根据体重指数(亚裔印度人的标准)进一步分为三组,根据WHR(腰臀比)分为两组。使用方差分析、Post-Hoc检验和线性回归检验对观察到的数据进行统计分析。结果:在我们的研究中,我们发现超重和肥胖的MVV值显著降低。肥胖男性MVV(L/Min)为68±10.80;超重男性为78.77±17.93,而非肥胖男性的相应值为112.61±19.42。根据方差分析,三组之间存在高度显著性(HS)差异(p 0.01)。多元回归方法显示与MVV呈高度显著性负相关(p<0.01)。结论:我们的研究得出结论,肺功能损害与成年超重和肥胖男性密切相关。通过减轻体重来降低BMI可以降低发病率。
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引用次数: 0
The Effect of Short Term Alcohol Abstinence on Neutrophil Phagocytic Properties 短期戒酒对中性粒细胞吞噬特性的影响
Pub Date : 2021-03-30 DOI: 10.37506/IJOP.V9I2.2922
S. Sushma, Sanjay M. Goudar
Background : Alcohol dysregulates the innate immunity in numerous ways, making alcohol dependantsmore susceptible to varied forms of infections and immunological assaults.Objective : The current study on alcoholics throws light on the consequence of short term alcohol abstinenceon neutrophil phagocytic power.Method : 21 subjects meeting the inclusion and exclusion criteria were enrolled for the study.Their bloodsamples were collected before and after a period of abstinence and studied for neutrophil phagocytic indexusing Candida phagocytic assay test.Result : An increase in the Mean Particle Number(MPN) of phagocytosis was observed in all the individualsafter the alcohol-free period.Conclusion : The improvement in phagocytic ability of neutrophils post-abstinence provides us an insightinto the ways alcohol manipulates the defense mechanism of the human body .Understanding this might helpus in exploring novel ideas to circumvent the mortality and morbidity in alcoholics.
背景:酒精以多种方式失调先天免疫,使酒精依赖者更容易受到各种形式的感染和免疫攻击。目的:目前对酗酒者的研究揭示了短期戒酒对中性粒细胞吞噬能力的影响。方法:21名符合纳入和排除标准的受试者被纳入本研究。在禁欲前后采集他们的血样,并使用念珠菌吞噬试验研究中性粒细胞吞噬指数。结果:在无酒精期后,所有个体的吞噬作用平均颗粒数(MPN)都有所增加。结论:戒酒后中性粒细胞吞噬能力的提高为我们深入了解酒精如何操纵人体防御机制提供了一个视角。了解这一点可能有助于我们探索规避酗酒者死亡率和发病率的新思路。
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引用次数: 0
期刊
International journal of physiology
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