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Bio-Electrochemical Cell Assisted Production of Biogenic Palladium Nanoparticles with Shewanella oneidensis MR-1 Bacteria for the Catalytic Removal of Ofloxacin (OFX) and Doxycycline (DOX) Micropollutants in Pharmaceutical Industry Wastewaters 生物电化学电池辅助下用希瓦氏菌MR-1细菌制备生物源钯纳米颗粒催化去除制药工业废水中的氧氟沙星(OFX)和强力霉素(DOX)微污染物
Pub Date : 2023-04-28 DOI: 10.31579/2690-4861/300
Delia Teresa Sponza
In this study, biogenic-palladium nanoparticles (bio-Pd NPs) with Shewanella oneidensis MR-1 bacteria as a heterostructure bio-electrochemical cell catalyts was examined during catalytic degradation process in the efficient removal of Ofloxacin (OFX) and Doxycycline (DOX) micropollutants from pharmaceutical industry wastewater plant, İzmir, Turkey. Different pH values (3.0, 4.0, 6.0, 7.0, 9.0 and 11.0), increasing micropollutants (OFX and DOX) concentrations (5 mg/l, 15 mg/l, 30 mg/l and 45 mg/l), increasing Bio-Pd NPs concentrations (5 mg/l, 10 mg/l, 20 mg/l, 30 mg/l, 40 mg/l and 60 mg/l), different Bio-Pd NPs/cell dry weight (CDW) mass ratios (5/5, 6/4, 7/3, 8/2, 9/1, 1/9, 2/8, 3/7 and 4/6), increasing recycle times (1., 2., 3., 4., 5., 6. and 7.) was operated during catalytic degradation process in the efficient removals of OFX and DOX micropollutants in pharmaceutical industry wastewater. The characteristics of the synthesized NPs were assessed using Diffuse reflectance UV-Vis spectra (DRS), Energy-dispersive X-ray (EDX), Field emission scanning electron microscopy (FESEM), Fourier transform infrared spectroscopy (FTIR), Inductively coupled plasma mass spectrometry (ICP-MS), Transmission Electron Microscopy (TEM), X-Ray Diffraction (XRD) and X-Ray Photoelectron Spectroscopy (XPS) analyses, respectively. The catalytic activity was first assessed by the degradation of methyl orange. The Bio-NPs showing the highest catalytic activity were selected for the removal of micropollutants (OFX and DOX) from secondary treated municipal wastewater. The catalytic degradation mechanisms of bio-Pd NPs with Shewanella oneidensis MR-1 bacteria as a heterostructure bio-electrochemical cell catalysts and the reaction kinetics of OFX and DOX micropollutants were evaluated in pharmaceutical industry wastewater during catalytic degradation process. ANOVA statistical analysis was used for all experimental samples. The maximum 99% OFX removal efficiency was obtained catalytic removals with bio-electrochemical cell assisted production of bio-Pd NPs with Shewanella oneidensis MR-1 bacteria bio-electrochemical cell catalyts in pharmaceutical industry wastewater, at 30 mg/l OFX concentration, 40 mg/l Bio-Pd NPs concentration, Bio-Pd NPs/CDW mass ratio=6/4, after 24 h catalytic degradation time, at pH=6.0, at 25oC, respectively. The maximum 99% DOX removal efficiency was observed catalytic removals with bio-electrochemical cell assisted production of bio-Pd NPs with Shewanella oneidensis MR-1 bacteria bio-electrochemical cell catalyts in pharmaceutical industry wastewater, at 30 mg/l DOX concentration, 40 mg/l Bio-Pd NPs concentration, Bio-Pd NPs/CDW mass ratio=6/4, after 24 h catalytic degradation time, at pH=9.0, at 25oC, respectively. Finally, the combination of a simple, easy operation preparation process, excellent performance and cost effective, makes this Bio-Pd NPs with Shewanella oneidensis MR-1 bacteria bio-electrochemical cell catalyts a promising option durin
在这项研究中,研究了生物钯纳米颗粒(bio-Pd NPs)以希瓦氏菌mr1作为异质结构生物电化学电池催化剂,在催化降解过程中有效去除来自土耳其İzmir制药工业废水厂的氧氟沙星(OFX)和强力霉素(DOX)微污染物。不同的pH值(3.0、4.0、6.0、7.0、9.0和11.0),增加微污染物(OFX和DOX)浓度(5 mg/l、15 mg/l、30 mg/l和45 mg/l),增加Bio-Pd NPs浓度(5 mg/l、10 mg/l、20 mg/l、30 mg/l、40 mg/l和60 mg/l),不同的Bio-Pd NPs/细胞干重(CDW)质量比(5/ 5,6 / 4,7 / 3,8 / 2,9 / 1,1 / 9,2 / 8,3 /7和4/6),增加循环次数(1。2。3。4。5。6。和7.)在催化降解过程中有效去除制药工业废水中的OFX和DOX微污染物。利用漫反射紫外-可见光谱(DRS)、能量色散x射线(EDX)、场发射扫描电子显微镜(FESEM)、傅里叶变换红外光谱(FTIR)、电感耦合等离子体质谱(ICP-MS)、透射电子显微镜(TEM)、x射线衍射(XRD)和x射线光电子能谱(XPS)分析对合成的NPs进行了表征。首先通过甲基橙的降解来评价其催化活性。选择催化活性最高的Bio-NPs用于去除二级处理城市废水中的微污染物(OFX和DOX)。研究了以希瓦氏菌MR-1为异质结构生物电化学电池催化剂的生物- pd NPs在制药废水中的催化降解机理,以及催化降解过程中OFX和DOX微污染物的反应动力学。所有实验样本均采用方差分析进行统计分析。在pH=6.0、温度为25℃的条件下,在生物电化学电池辅助下,在30 mg/l的OFX浓度、40 mg/l的bio-Pd NPs浓度、bio-Pd NPs/CDW质量比=6/4的条件下,催化降解时间为24 h,获得了最高99%的OFX去除率。在pH=9.0、温度为25℃条件下,在生物电化学电池辅助下,在30 mg/l DOX浓度、40 mg/l bio-Pd NPs浓度、bio-Pd NPs/CDW质量比=6/4的条件下,对制药工业废水进行催化降解,降解时间为24 h,降解效率最高达99%。最后,结合简单、易于操作的制备工艺、优异的性能和成本效益,使该带有希瓦氏菌MR-1细菌生物电化学电池催化剂的Bio-Pd NPs在制药工业废水处理的催化降解过程中成为一种有前景的选择。
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引用次数: 0
Treatment with Colchicine in an Undiagnosed 45-year-old Female Patient with Diffuse Abdominal and Flank Pain for more than 5 years 秋水仙碱治疗45岁女性弥漫性腹部及腹部疼痛5年以上患者
Pub Date : 2023-04-28 DOI: 10.31579/2690-4861/308
Ali Osman AVCI
A 45-year-old female patient living abroad has severe abdominal and flank pain that persists for more than 5 years and recurs several times a month. She never had a fever when the pain developed. For more than 5 years, no pathology was detected in the patient's blood and urine tests, abdominal ultrasound and computed tomography. Analgesics and antispasmodics used for the patient's pain are not effective at all, and the patient is relieved with narcotic analgesics in every painful attack. Finally, the patient who came to our hospital with severe abdominal and flank pain was first relieved with narcotic analgesics due to her detailed history, then blood, urine tests and abdominal ultrasound were performed, but no pathology was detected. Considering the possibility of atypical FMF, colchicine treatment was considered for the patient. With the patient's approval, oral 0.6 mg of colchicine was started 3 times a day and the patient were followed up. At the controls 1 week, 1 month and 3 months later, it was observed that the patient did not have any painful attacks, and no colchicine-related side effects were observed. FMF not only progresses with painful attacks, but also amyloid A (AA) amyloidosis, which is a fatal complication, can affect the kidneys and cause kidney failure. Therefore, colchicine treatment should be tried before narcotic analgesics in all patients with abdominal and flank pain who have normal examination findings, laboratory tests and radiological imaging findings, and even negative FMF gene analysis.
45岁女性患者,旅居国外,腹部及腹部疼痛严重,持续5年以上,每月复发数次。疼痛发作时她从不发烧。在5年多的时间里,患者的血液和尿液检查、腹部超声和计算机断层扫描均未发现病理。用于治疗患者疼痛的镇痛药和抗痉挛药完全无效,每次疼痛发作时患者都用麻醉性镇痛药缓解。最后,该患者因腹部及侧腹疼痛严重而来我院就诊,根据其详细病史,我们先用麻醉性镇痛药缓解,然后进行了血液、尿液检查和腹部超声检查,但未发现病理。考虑到不典型FMF的可能性,考虑对患者使用秋水仙碱治疗。经患者同意,开始口服秋水仙碱0.6 mg,每日3次,并对患者进行随访。对照组1周、1个月和3个月后,观察患者无任何疼痛发作,无秋水仙碱相关副作用。FMF不仅会伴有疼痛发作,还会发生淀粉样蛋白A (AA)淀粉样变性,这是一种致命的并发症,可影响肾脏并导致肾衰竭。因此,对于所有检查结果、实验室检查和影像学检查结果正常,甚至FMF基因分析阴性的腹部和腹部疼痛患者,应先尝试秋水仙碱治疗,再使用麻醉性镇痛药物。
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引用次数: 0
The Impact of Coronavirus Disease 2019 (COVID-19) on Lung Function, Exercise Capacity and Quality of Life in a Cohort of Survivors 2019冠状病毒病(COVID-19)对幸存者队列肺功能、运动能力和生活质量的影响
Pub Date : 2023-04-28 DOI: 10.31579/2690-4861/306
Chin Tong Kwok
Background: The lung function outcome among COVID-19 survivors in Hong Kong remained unknown. Methods: Patients above the age of 18 years old with the principal diagnosis of COVID-19 who were discharged from a tertiary center in Hong Kong between the period of 1st February 2020 to 31st July 2020 were offered three lung function tests at approximately one, three and six months upon discharge for monitoring of their outcome. Six-minute walk test (6MWT) and health related quality of life assessment by Medical Outcomes Study 36-item Short Form General Health Survey (SF-36) were arranged on the same day of lung function test. Results: Thirty patients had lung function test performed within 60 days after discharge. Nineteen and twelve patients had lung function test performed at 60-180 days and 180 days after discharge respectively. After corrected for underlying lung diseases, 32% patients have reduced hemoglobin adjusted DLCO and PImax, while 88% patients have reduced PEmax. For patients with serial lung function performed, adjusted DLCO and PImax improved with time. The exercise capacity of COVID-19 survivors was significantly lower than normal subjects in most age groups. COVID-19 survivors have lower quality of life in the context of physical functioning, social functioning and role limitation due to physical problems, compared with normal subjects. Conclusion: COVID-19 leads to lung function abnormalities including reduced diffusing capacity of carbon monoxide, maximal inspiratory pressure and maximal expiratory pressure in more than 40% of patients, which improved with time. Exercise capacity and health status of COVID-19 survivors are lower than normal subjects.
背景:香港COVID-19幸存者的肺功能结局尚不清楚。方法:在2020年2月1日至2020年7月31日期间从香港某三级医疗中心出院的18岁以上主要诊断为COVID-19的患者,分别在出院后约1个月、3个月和6个月进行三次肺功能检查,以监测其预后。在肺功能测试的同一天进行6分钟步行测试(6MWT)和《医学结局研究》36项简短健康调查(SF-36)的健康相关生活质量评估。结果:30例患者出院后60天内行肺功能检查。19例和12例分别于出院后60 ~ 180天和180天进行肺功能检查。在纠正肺部潜在疾病后,32%的患者血红蛋白调整DLCO和PImax降低,88%的患者PEmax降低。对于连续肺功能的患者,调整后的DLCO和PImax随着时间的推移而改善。在大多数年龄组中,COVID-19幸存者的运动能力明显低于正常受试者。与正常受试者相比,COVID-19幸存者在身体功能、社会功能和角色限制方面的生活质量较低。结论:新型冠状病毒肺炎导致超过40%的患者出现一氧化碳弥散量降低、最大吸气压和最大呼气压降低等肺功能异常,随时间推移而改善。COVID-19幸存者的运动能力和健康状况低于正常受试者。
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引用次数: 0
Red Blood Cell Exchange for a Patient with Dapsone-Induced Methemoglobinemia, Severe Methylene Blue Allergy, and Refractoriness to Intravenous Vitamin C Therapy 1例氨苯砜致高铁血红蛋白血症、严重亚甲基蓝过敏和静脉维生素C治疗难治性患者的红细胞交换
Pub Date : 2023-04-03 DOI: 10.46527/2582-5038.249
Aria Kenarsary, Erik Sanson, Adam Stepanovic, R. Mattison, Xiaoyang Yang, J. Connor, W. N. Rose
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引用次数: 0
Review Article on Breast Cancer Awareness in Nigeria 关于尼日利亚乳腺癌意识的综述文章
Pub Date : 2023-04-03 DOI: 10.46527/2582-5038.252
Rex Friday Ogoronte Alderton Ijah, Christiana N. Ijah
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引用次数: 0
Allergic Contact Dermatitis to Povidone Iodine Mimicking Surgical Site Infection - A Diagnostic Dilemma 聚维酮碘致过敏性接触性皮炎模拟手术部位感染-诊断困境
Pub Date : 2023-04-03 DOI: 10.46527/2582-5038.250
Karthikayan Vr, Neikhro Zhiemi, Aravindakshan Tk, S. Raninga
{"title":"Allergic Contact Dermatitis to Povidone Iodine Mimicking Surgical Site Infection - A Diagnostic Dilemma","authors":"Karthikayan Vr, Neikhro Zhiemi, Aravindakshan Tk, S. Raninga","doi":"10.46527/2582-5038.250","DOIUrl":"https://doi.org/10.46527/2582-5038.250","url":null,"abstract":"","PeriodicalId":93010,"journal":{"name":"International journal of clinical case reports and reviews : open access","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74438922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case of the Successful using the Gastro-Jejunal with Jejuno-Jejunal Anastomoses (and Gastropexy) for Treatment of the Cascade Stomach 胃-空肠吻合术(加胃固定术)治疗级联胃成功一例
Pub Date : 2023-04-03 DOI: 10.46527/2582-5038.248
Oleksandr M. Bondar, Olena O. Kovalska, Yalisa H. Paneque
Citation: Bondar OM, Kovalska OO, Paneque YH. Case of the Successful using the Gastro-Jejunal with Jejuno-Jejunal Anastomoses (and Gastropexy) for Treatment of the Cascade Stomach. Clin Case Rep Open Access. 2023;6(2):248
引用本文:Bondar OM, Kovalska OO, Paneque YH。胃-空肠吻合术(加胃固定术)治疗级联胃成功一例。临床病例报告开放获取。2023;6(2):248
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引用次数: 0
Coarctation of the Aorta with Patent Ductus Arteriosus in an Adult, a CT Angiographic Overview 成人主动脉缩窄伴动脉导管未闭的CT血管造影综述
Pub Date : 2023-04-03 DOI: 10.46527/2582-5038.251
Echchikhi M, Ayouch O, Ben El Hosni K, N. I, Moatassim Billah N
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引用次数: 0
Interesting Case of Disseminated Herpes Infection in A Healthy Female Patient Resembling Monkeypox 一例类似猴痘的健康女性患者弥散性疱疹感染的有趣病例
Pub Date : 2023-03-31 DOI: 10.31579/2690-4861/302
Ashley Thakur
Normally we find cases of disseminated cutaneous herpes-simplex in immunocompromised individuals. With the advent of monkeypox, many reports have been falsely purporting cases of this disease when the lesions were either herpes simplex or an unspecified skin infection. In this case report we document the finding of a healthy 31-year-old female with herpetic lesions on her arms, legs, and vulvar area.
通常我们发现病例播散性皮肤单纯疱疹在免疫功能低下的个体。随着猴痘的出现,许多报告错误地声称这种疾病的病例,当病变是单纯疱疹或未指明的皮肤感染。在这个病例报告中,我们记录了一名健康的31岁女性,她的手臂,腿部和外阴区域有疱疹性病变。
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引用次数: 0
What are the Causes of Variation in Vaccination Rates Between Countries? Empirical Evidence from a Set of Developed and Developing Countries 国家间疫苗接种率差异的原因是什么?一组发达国家和发展中国家的经验证据
Pub Date : 2023-03-31 DOI: 10.31579/2690-4861/270
Imen Ghannouchi
Over two years, the Coronavirus pandemic radically changed the worldwide people's lifestyles and widely affected the socioeconomic environment. However, the development of new vaccines against covid-19 seems to be the first and only hope to mitigate this pandemic and go back to normal life. Several mass vaccination campaigns have been planned to vaccinate as many people as possible. Nonetheless, a wide range of people did not take their vaccines for hesitancy reason of the inequality of disturbance of vaccines. Hence, focusing on the macroeconomic factors, this study outlines the primary causes of the gap in vaccination rates between countries, specifically between developed and developing countries. The results provide interested insights: GDP has a positive and significant effect on the vaccination rate. However, the rural population rate negatively affects the vaccination rate. It is noteworthy that a more equitable disturbance of vaccines is required. Moreover, mass media campaign should be omnipresent to encourage people, particularly in rural zones, to obtain the vaccine.
两年多来,冠状病毒大流行从根本上改变了全球人民的生活方式,广泛影响了社会经济环境。然而,针对covid-19的新疫苗的开发似乎是缓解这场大流行并恢复正常生活的第一个也是唯一的希望。已计划开展几次大规模疫苗接种运动,为尽可能多的人接种疫苗。然而,由于疫苗干扰的不平等,很多人因为犹豫而不接种疫苗。因此,本研究侧重于宏观经济因素,概述了国家之间,特别是发达国家和发展中国家之间疫苗接种率差距的主要原因。结果提供了有趣的见解:GDP对疫苗接种率有显著的正影响。然而,农村人口接种率对疫苗接种率有负面影响。值得注意的是,需要对疫苗进行更公平的干扰。此外,应无处不在地开展大众媒体宣传运动,鼓励人们,特别是农村地区的人们接种疫苗。
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引用次数: 0
期刊
International journal of clinical case reports and reviews : open access
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