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Évaluation de l’efficacité des moustiquaires imprégnées 36 mois après leur distribution dans le Sud Cameroun 在喀麦隆南部分发经处理的蚊帐36个月后的有效性评估
Q4 Medicine Pub Date : 2020-12-28 DOI: 10.3166/BSPE-2020-0159
FN Nopowo
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引用次数: 2
Pratiques et facteurs associés au dépistage récent du VIH en population générale, Côte d’Ivoire. Résultats de l’étude ANRS 12323 DOD-CI 科特迪瓦普通人群中与近期艾滋病毒检测相关的做法和因素。ANRS 12323 DOD-CI研究结果
Q4 Medicine Pub Date : 2020-12-28 DOI: 10.3166/BSPE-2020-0154
M. Inghels
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引用次数: 0
Comportements sexuels à risque d’infection à VIH chez les transgenres homme vers femme au Bénin 贝宁男女变性人感染艾滋病毒风险的性行为
Q4 Medicine Pub Date : 2020-12-28 DOI: 10.3166/BSPE-2020-0158
S. Hessou
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引用次数: 0
Dynamique d’abondance des charges oocystiques dans les eaux souterraines de Mbankomo, une zone périurbaine de Yaoundé : physicochimie et risque sanitaire yaounde郊区Mbankomo地下水含水层丰度动态:物理化学和健康风险
Q4 Medicine Pub Date : 2020-12-28 DOI: 10.3166/BSPE-2020-0155
A. A. Quiggle
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引用次数: 0
[Selected Abstracts from the VERE 2019: Congress on Emerging and Re-Emerging Viral Infections]. [VERE 2019:新发和再发病毒感染大会精选摘要]。
Q4 Medicine Pub Date : 2020-06-28 DOI: 10.3166/bspe-2020-0134
R. Taty-Taty
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引用次数: 0
Une coalition mondiale pour promouvoir la recherche clinique sur le Covid-19 dans des environnements à ressources limitées 在资源有限的环境中促进COVID-19临床研究的全球联盟
Q4 Medicine Pub Date : 2020-04-28 DOI: 10.3166/BSPE-2020-0123
Covid Clinical Reserach Coalition
There is not yet a vaccine against severe acute respiratory syndrome coronavirus infections 2 (SARSCoV-2) and no drug with proven clinical efficacy, although several candidates could be effective in prevention or treatment. It is encouraging that the response of the research community to the 2019 coronavirus pandemic (Covid-19) has been strong. A review of clinical trial registries, as of March 24, 2020, identified 536 relevant clinical trials already registered. Of the 332 clinical trials linked to Covid-19, 188 are open for recruitment and 146 trials will be soon. These clinical trials are located in the countries most affected by Covid-19 over the past two months, in particular China and South Korea, as high-income countries in Europe and North America prepare most of the next clinical trials. Very few trials are planned in Africa, South and Southeast Asia, and Central and South America. The number of confirmed Covid-19 cases reported in resource-constrained settings is still relatively low, but the availability of diagnostic tests there is also limited and the number of Covid-19 cases looks set to increase dramatically in the coming weeks. The capacity of precarious health systems to manage an outbreak of severe pneumonia is limited, and the low availability of appropriate personal protective equipment for frontline health workers means that these key staff are susceptible to massive infection with the disease. Covid-19. A disruption or complete shutdown of these health care systems would result in high direct and indirect mortality, as care for all diseases would be affected.
目前还没有针对严重急性呼吸综合征冠状病毒感染2 (SARSCoV-2)的疫苗,也没有临床疗效得到证实的药物,尽管有几种候选药物可能在预防或治疗方面有效。令人鼓舞的是,研究界对2019年冠状病毒大流行(Covid-19)的反应非常强烈。截至2020年3月24日,对临床试验注册的审查发现,已有536项相关临床试验注册。在与Covid-19相关的332项临床试验中,188项正在开放招募,146项试验即将进行。这些临床试验位于过去两个月受Covid-19影响最严重的国家,特别是中国和韩国,因为欧洲和北美的高收入国家准备了大部分后续临床试验。计划在非洲、南亚和东南亚以及中美洲和南美洲进行的试验很少。在资源紧张的环境中报告的Covid-19确诊病例数量仍然相对较低,但那里的诊断测试的可用性也有限,未来几周Covid-19病例数量似乎将大幅增加。不稳定的卫生系统管理严重肺炎暴发的能力有限,而且一线卫生工作者获得适当个人防护装备的机会很少,这意味着这些关键工作人员容易受到这种疾病的大规模感染。新型冠状病毒肺炎这些卫生保健系统的中断或完全关闭将导致高直接和间接死亡率,因为对所有疾病的护理都将受到影响。
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引用次数: 0
[Prevalence and Management of Snake Bite Envenomation at the Regional Hospital Center of Sokodé (Togo)]. [sokod<s:1>(多哥)地区医院中心蛇咬伤中毒的流行及处理]。
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.3166/bspe-2020-0145
L D Bawe, A Kotosso, K D Nemi, B Abaltou, A R Moukaïla, T Blatome, A N'Djao, A A Patassi, Wateba M I

Snakebite envenomation (SBE) is a public health issue in Africa, unfortunately neglected and underestimated. SBE is a medical emergency that can be devastating and lifethreatening. A retrospective study was performed from January 1, 2016 to December 31, 2016 in the general medicine department of the Regional Hospital Center (CHR), Sokodé. We included 91 SBE accounting for 5.7% of the whole hospitalizations in the general medicine department at the CHR of Sokodé. The median age of the patients was 34 [23.5-42] with male predominance (59%). Farming activities (75%) and walking (24%) were the most frequent activities when SBE happened, and they occurred mostly in rural areas (80%) during the dry season (56%). Echis genus (37%) belonging to the Viperidae family was the king of snake most often identified. Hospital admission time after a bite often exceeded 24 hours (44%). Clinical manifestations resulted in 76 cases of viper syndrome (83%) and 7 cases of dry bites (8%). Antivenom was administered in 84 cases (92%) within 12 hours (54%) after the bite with a minimum dose of 20 mL (43%). Observed complications were severe anemia (19 cases) and diffuse hemorrhage (32 cases). Case fatality rate was 9%. Antivenom is critical in cases of obvious SBE. High cost and poor access of antivenom, in addition to delayed care due to traditional treatment seeking behavior, are factors of poor prognosis.

蛇咬伤中毒(SBE)是非洲的一个公共卫生问题,不幸的是被忽视和低估了。SBE是一种医疗紧急情况,可能是毁灭性的和危及生命的。回顾性研究于2016年1月1日至2016年12月31日在sokod地区医院中心(CHR)普通内科进行。我们纳入了91例SBE,占索科医院全科住院总人数的5.7%。患者中位年龄34岁[23.5-42],男性居多(59%)。农业活动(75%)和步行(24%)是SBE发生时最常见的活动,主要发生在农村(80%)旱季(56%)。蛇属(37%)是最常被发现的蛇之王,隶属于毒蛇科。咬伤后住院时间通常超过24小时(44%)。临床表现为毒蛇综合征76例(83%),干性咬伤7例(8%)。84例(92%)在咬伤后12小时内(54%)使用抗蛇毒血清,最小剂量为20ml(43%)。并发症为严重贫血19例,弥漫性出血32例。病死率为9%。抗蛇毒血清对明显的SBE至关重要。高成本和难以获得抗蛇毒血清,以及由于传统的寻求治疗行为而导致的延迟护理,是预后不良的因素。
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引用次数: 1
[Responses to the Risk of Canine and Human Rabies in the City of Sibut, Central African Republic]. [中非共和国Sibut市对犬类和人类狂犬病风险的应对措施]。
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.3166/bspe-2020-0118
E Kalthan, F Ouayo Banawane, E F Yagata-Moussa, M N Mbaikoua, D Wea-Yougaye

In Sibut (CAR), the increase in bites by stray dogs and two cases of human rabies alerted health authorities in 2019. The answers were the vaccinations of humans and of dog (780 dogs). Among the 127 humans bitten and identified, 87% received a first injection of post-exposure prophylaxis. The drop-out between the first and third doses was 41%. Communication on rabies and the provision of vaccines and serums to the population are necessary, but difficult to achieve in the crisis conditions of the country.

2019年,在中非共和国Sibut,流浪狗咬伤病例的增加和两例人类狂犬病病例引起了卫生当局的警觉。答案是人类和狗的疫苗接种(780只狗)。在被咬伤并确定的127人中,87%接受了首次接触后预防注射。第一次和第三次注射之间的辍学率为41%。关于狂犬病的宣传和向民众提供疫苗和血清是必要的,但在该国的危机条件下很难做到。
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引用次数: 1
[Abundance Dynamic of Oocysts in the Groundwater of Mbankomo, a Sub-urban Area Yaounde: Physico-chemical Factors and Health Risk]. [雅温得郊区Mbankomo地下水卵囊丰度动态:理化因素和健康风险]。
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.3166/bspe-2021-0155
A Asi Quiggle, A Ajeagah Gideon, T N Okoa Amougou

To determine the dynamics of dissemination of the different forms of enteric sporozoa in the groundwater of Mbankomo, a study was carried out from August 2018 to July 2019. The physico-chemical analyzes were carried out both in the field and in the hydrobiology and environment laboratory of the University of Yaoundé I. The observation of protozoan oocysts was carried out after application of the Ziehl-Neelsen staining. Physico-chemical analysis showed slightly acidic water (6.32 ± 0.43 UC), with high turbidity (31.30 ± 23.56 mg/l). Biological analysis indicated the presence of protozoan oocysts with an average density of 42 ± 69 oocysts/l of Cryptosporidium spp., 17 ± 34 oocysts/l of Cyclospora cayetanensis, 9 ± 19 oocysts/l of Isospora belli and 6 ± 11 oocysts/l of Sarcocystis spp. The highest concentrations of oocysts were recorded during the rainy season. Statistical tests showed a positive correlation between the densities of oocysts with suspended matters (P < 0.05).

为了确定姆班科莫地下水中不同形式肠道孢子虫的传播动态,研究人员于2018年8月至2019年7月进行了一项研究。在野外和雅温得大学水生生物与环境实验室进行了理化分析。采用Ziehl-Neelsen染色法观察原生动物卵囊。理化分析显示:微酸性水(6.32±0.43 UC),高浊度(31.30±23.56 mg/l)。生物分析结果显示,虫体中存在原生动物卵囊,平均密度为隐孢子虫42±69个/l、卡耶塔环孢子虫17±34个/l、贝氏异孢子虫9±19个/l、肉囊虫6±11个/l,以雨季卵囊密度最高。经统计学检验,卵囊密度与悬浮物呈正相关(P < 0.05)。
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引用次数: 0
[Acute Flaccid Paralysis Secondary to Poliomyelitis: 11 Years of Monitoring in Guinea (2005-2015)]. [脊髓灰质炎继发急性弛缓性麻痹:几内亚11年监测(2005-2015)]。
Q4 Medicine Pub Date : 2020-01-01 DOI: 10.3166/bspe-2020-0116
K Sylla, M S Sow, M O S Diallo, M M Sy, F B Sako, F A Traoré, I Bah, M O Cissé, D C Sow, M S Baldé, A M Diallo

The sustained worldwide use of the two available types of polio vaccines has significantly reduced the incidence of this disease. Our main objective is to report a 11-year monitoring period for acute flaccid paralysis secondary to poliovirus in Guinea. It was a retrospective descriptive study for all cases of acute flaccid paralysis (AFP) in which poliovirus was isolated by stool examination. During 11 years, 768 cases of AFP, including 8 cases of acute anterior poliomyelitis were collected at a frequency of 1%. The average age was 3.5 years with extremes of 1 year and 6 years, the most represented age group was 0-4 years with 7 cases. Six mothers were housewives doing gold panning as a revenue generating activity. The vaccine virus (serotype 2) was the most isolated with 6 cases.

在世界范围内持续使用两种现有的脊髓灰质炎疫苗,大大减少了这种疾病的发病率。我们的主要目标是报告几内亚继发于脊髓灰质炎病毒的急性弛缓性麻痹的11年监测期。这是一个回顾性的描述性研究,所有病例的急性弛缓性麻痹(AFP),脊髓灰质炎病毒分离的粪便检查。11年间共收集AFP病例768例,其中急性前路脊髓灰质炎8例,发生率为1%。平均年龄为3.5岁,极端年龄为1岁和6岁,以0-4岁年龄组最多,共7例。六位母亲都是家庭主妇,以淘金为生。疫苗病毒(血清2型)分离最多,共6例。
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引用次数: 1
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Bulletin de la Societe de pathologie exotique
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