R. Gündüz, S. Yaman Tunc, M. Icen, S. Ertuğrul, T. Gül
OBJECTIVE: To determine the perinatal mortality rate in patients with HELLP syndrome in our clinic and to investigate the factors affecting perinatal mortality. It also makes recommendations to reduce perinatal mortality and contributes to the literature. STUDY DESIGN: Three-hundred-and-eighty-three patients were retrospectively evaluated in this cohort study. The patients' demographic, clinical data, laboratory results, gestational week at delivery, method of delivery, neonatal birth weight, fetal gender, 1and 5-minute APGAR scores, place of delivery, maternal morbidity, mortality rates, and perinatal mortality rates were recorded. The relationship of these factors with perinatal mortality was investigated. RESULTS: The rate of perinatal mortality was determined as 6%. Patients with HELLP syndrome who experienced perinatal mortality showed significantly lower birth weight, gestational age at delivery, and 1and 5-minute APGAR score values (p<0.05). With respect to methods of delivery, we determined that vaginal delivery was linked to a significantly higher rate of perinatal mortality (p<0.001). Gestational age at delivery, birth weight, 1and 5-minute APGAR scores were negatively correlated with perinatal mortality. Logistic regression revealed the APGAR score at 5 minutes as the most reliable independent predictive finding for perinatal mortality. CONCLUSION: We think that to decrease perinatal mortality rates, maternal and fetal well-being in patients with HELLP syndrome should be closely monitored and delivery and follow-up should take place at tertiary health institutions after maternal and neonatal intensive care arrangements are made. Particularly, neonates with low 5-minute APGAR scores in the postpartum evaluation of neonatal condition are recommended to be followed-up at the neonatal intensive care unit.
{"title":"Evaluation of Factors Affecting Perinatal Mortality in Patients with HELLP Syndrome","authors":"R. Gündüz, S. Yaman Tunc, M. Icen, S. Ertuğrul, T. Gül","doi":"10.21613/GORM.2021.1144","DOIUrl":"https://doi.org/10.21613/GORM.2021.1144","url":null,"abstract":"OBJECTIVE: To determine the perinatal mortality rate in patients with HELLP syndrome in our clinic and to investigate the factors affecting perinatal mortality. It also makes recommendations to reduce perinatal mortality and contributes to the literature. STUDY DESIGN: Three-hundred-and-eighty-three patients were retrospectively evaluated in this cohort study. The patients' demographic, clinical data, laboratory results, gestational week at delivery, method of delivery, neonatal birth weight, fetal gender, 1and 5-minute APGAR scores, place of delivery, maternal morbidity, mortality rates, and perinatal mortality rates were recorded. The relationship of these factors with perinatal mortality was investigated. RESULTS: The rate of perinatal mortality was determined as 6%. Patients with HELLP syndrome who experienced perinatal mortality showed significantly lower birth weight, gestational age at delivery, and 1and 5-minute APGAR score values (p<0.05). With respect to methods of delivery, we determined that vaginal delivery was linked to a significantly higher rate of perinatal mortality (p<0.001). Gestational age at delivery, birth weight, 1and 5-minute APGAR scores were negatively correlated with perinatal mortality. Logistic regression revealed the APGAR score at 5 minutes as the most reliable independent predictive finding for perinatal mortality. CONCLUSION: We think that to decrease perinatal mortality rates, maternal and fetal well-being in patients with HELLP syndrome should be closely monitored and delivery and follow-up should take place at tertiary health institutions after maternal and neonatal intensive care arrangements are made. Particularly, neonates with low 5-minute APGAR scores in the postpartum evaluation of neonatal condition are recommended to be followed-up at the neonatal intensive care unit.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73226420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peripartum cardiomyopathy is a rare type of cardiomyopathy. Peripartum cardiomyopathy is a potentially life-threatening pregnancy-associated disease that typically arises in the peripartum period and is marked with left ventricular dysfunction and heart failure. The cause of peripartum cardiomyopathy remains unclear, but several mechanisms have been proposed which indices a potentially multi-factorial etiologies. Early case reports identified overlap between familial dilated cardiomyopathy and peripartum cardiomyopathy, although the degree of overlap is largely unknown. Evidence supporting a contribution from gene mutations in peripartum cardiomyopathy includes genome-wide association studies, familial occurrence, variable prevalence among different regions and ethnicities, and more recent investigations of panels of genes for mutations among women with peripartum cardiomyopathy. Although the true incidence of genetic cardiomyopathy is not yet known among women with peripartum cardiomyopathy, there is substantial evidence demonstrating that genetic contribution to their condition.
{"title":"Genetic Polymorphism in Peripartum Cardiomyopathy","authors":"I. Dewi, J. Nugroho","doi":"10.21613/GORM.2021.1072","DOIUrl":"https://doi.org/10.21613/GORM.2021.1072","url":null,"abstract":"Peripartum cardiomyopathy is a rare type of cardiomyopathy. Peripartum cardiomyopathy is a potentially life-threatening pregnancy-associated disease that typically arises in the peripartum period and is marked with left ventricular dysfunction and heart failure. The cause of peripartum cardiomyopathy remains unclear, but several mechanisms have been proposed which indices a potentially multi-factorial etiologies. Early case reports identified overlap between familial dilated cardiomyopathy and peripartum cardiomyopathy, although the degree of overlap is largely unknown. Evidence supporting a contribution from gene mutations in peripartum cardiomyopathy includes genome-wide association studies, familial occurrence, variable prevalence among different regions and ethnicities, and more recent investigations of panels of genes for mutations among women with peripartum cardiomyopathy. Although the true incidence of genetic cardiomyopathy is not yet known among women with peripartum cardiomyopathy, there is substantial evidence demonstrating that genetic contribution to their condition.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79241181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Kasapoğlu, K. Aslan, A. Orhan, Ozge Albayrak, Seyma Haskoylu, G. Kuspinar, B. Avcı, G. Uncu
OBJECTIVE: To evaluate the effect of the embryo transfer duration of standard and simple embryo transfer method. STUDY DESIGN: This study was a retrospective cohort study conducted at a tertiary ART Centre, between June 2018- September 2018. Day 5 fresh embryo transferred patients aged between 18 - 40, BMI <35 kg/m2 without uterine pathology were enrolled in the study. Patients were divided into two groups. Group-1 consisted of patients who had successful implantation and Group-2 consisted of patients who did not have implantation. Groups were compared according to their embryo transfer durations. Ninety-two patients were enrolled in the study. Also, sub-steps of as; cleaning of the cervical mucus and placing the outer catheter in the cervix, loading the embryo to the catheter, the period between embryo loading and embryo transfer, and following that, time spent for retracting the outer catheter evaluated. RESULTS: Between Group-1 and Group-2, there was no significant difference for the period of cervical cleaning and placing the outer catheter into the cervix (Respectively; 63 sec vs. 76 sec; p=0.18), the period of embryo loading (Respectively; 69sec vs. 71sec; p=0.46), the period between embryo loading and embryo transfer (Respectively; 10 sec vs. 10 sec; p=0.74, retracing the outer catheter (Respectively; 25.5sec vs. 24sec; p=0.42 and the total period of embryo transfer (182sec vs. 182.5 sec; p=0.55). CONCLUSION: The embryo transfer duration is not related to implantation rates. The duration of the embryo transfer process steps is not a distinguishing factor if a good-quality embryo transfer is done.
目的:评价标准胚胎移植方法与简易胚胎移植方法对胚胎移植时间的影响。研究设计:本研究是一项回顾性队列研究，于2018年6月至2018年9月在一所高等艺术中心进行。第5天新鲜胚胎移植患者年龄在18 - 40岁之间，BMI <35 kg/m2，无子宫病理。患者分为两组。第一组为种植成功的患者，第二组为未种植的患者。各组按胚胎移植时间进行比较。92名患者参加了这项研究。还有as的子步骤;清除宫颈粘液，将外置导管置入宫颈，将胚胎装入导管，胚胎装入与胚胎移植之间的时间，以及之后收回外置导管所花费的时间。结果:组1与组2在宫颈清扫时间、外置导管置入宫颈时间(分别为;63 SEC vs. 76 SEC;p=0.18)，胚胎加载期(分别为;69秒vs. 71秒;p=0.46)，胚胎装载和胚胎移植之间的时间(分别为;10秒vs 10秒;p=0.74，外置导管回撤(分别;25.5秒vs. 24秒;P =0.42，胚胎移植总时间(182sec vs. 182.5 sec;p = 0.55)。结论:胚胎移植时间与着床率无关。如果进行了高质量的胚胎移植，胚胎移植过程步骤的持续时间并不是一个区分因素。
{"title":"The Effect of Embryo Transfer Process Duration on Implantation Success","authors":"I. Kasapoğlu, K. Aslan, A. Orhan, Ozge Albayrak, Seyma Haskoylu, G. Kuspinar, B. Avcı, G. Uncu","doi":"10.21613/GORM.2021.1089","DOIUrl":"https://doi.org/10.21613/GORM.2021.1089","url":null,"abstract":"OBJECTIVE: To evaluate the effect of the embryo transfer duration of standard and simple embryo transfer method. \u0000STUDY DESIGN: This study was a retrospective cohort study conducted at a tertiary ART Centre, between June 2018- September 2018. Day 5 fresh embryo transferred patients aged between 18 - 40, BMI <35 kg/m2 without uterine pathology were enrolled in the study. Patients were divided into two groups. Group-1 consisted of patients who had successful implantation and Group-2 consisted of patients who did not have implantation. Groups were compared according to their embryo transfer durations. Ninety-two patients were enrolled in the study. Also, sub-steps of as; cleaning of the cervical mucus and placing the outer catheter in the cervix, loading the embryo to the catheter, the period between embryo loading and embryo transfer, and following that, time spent for retracting the outer catheter evaluated.\u0000RESULTS: Between Group-1 and Group-2, there was no significant difference for the period of cervical cleaning and placing the outer catheter into the cervix (Respectively; 63 sec vs. 76 sec; p=0.18), the period of embryo loading (Respectively; 69sec vs. 71sec; p=0.46), the period between embryo loading and embryo transfer (Respectively; 10 sec vs. 10 sec; p=0.74, retracing the outer catheter (Respectively; 25.5sec vs. 24sec; p=0.42 and the total period of embryo transfer (182sec vs. 182.5 sec; p=0.55).\u0000CONCLUSION: The embryo transfer duration is not related to implantation rates. The duration of the embryo transfer process steps is not a distinguishing factor if a good-quality embryo transfer is done.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75134586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OBJECTIVE: To compare the presence of eosinophilia and basophilia between two groups with and without bronchopulmonary dysplasia in preterm infants and, to investigate whether there was a correlation between the bronchopulmonary dysplasia severity and degree of eosinophilia. STUDY DESIGN: In this retrospective cohort study, we have evaluated premature babies who were admitted between 2007 and 2017 to the Neonatal Intensive Care Unit of Hacettepe Hospital. Hospital records were scanned and 85 preterm infants diagnosed with bronchopulmonary dysplasia formed the study group while 89 babies without bronchopulmonary dysplasia formed the control group. Necessary demographic, neonatal, and laboratory data were withdrawn from the electronic registry and patient files. RESULTS: In the study group, there was a statistically significant difference in the severity of eosinophilia and basophilia in the first day, first week, second week, third week, and fourth week compared to the control group (p<0.05). According to the mixed effect model, after adjusting results for gestational age and birth weight there was a statistically significant difference between groups in terms of eosinophil and basophil values (p<0.05). CONCLUSION: The number of eosinophils and basophils increased in patients with bronchopulmonary dysplasia without an increase in the number of leukocytes.
{"title":"PREDICTIVE VALUE OF EOSINOPHILIA AND BASOPHILIA IN THE DIAGNOSIS OF BRONCHOPULMONARY DYSPLASIA IN PREMATURE INFANTS","authors":"Melek Büyükeren, H. Çelik, Ş. Yiğit, M. Yurdakök","doi":"10.21613/GORM.2021.1171","DOIUrl":"https://doi.org/10.21613/GORM.2021.1171","url":null,"abstract":"OBJECTIVE: To compare the presence of eosinophilia and basophilia between two groups with and without bronchopulmonary dysplasia in preterm infants and, to investigate whether there was a correlation between the bronchopulmonary dysplasia severity and degree of eosinophilia. STUDY DESIGN: In this retrospective cohort study, we have evaluated premature babies who were admitted between 2007 and 2017 to the Neonatal Intensive Care Unit of Hacettepe Hospital. Hospital records were scanned and 85 preterm infants diagnosed with bronchopulmonary dysplasia formed the study group while 89 babies without bronchopulmonary dysplasia formed the control group. Necessary demographic, neonatal, and laboratory data were withdrawn from the electronic registry and patient files. RESULTS: In the study group, there was a statistically significant difference in the severity of eosinophilia and basophilia in the first day, first week, second week, third week, and fourth week compared to the control group (p<0.05). According to the mixed effect model, after adjusting results for gestational age and birth weight there was a statistically significant difference between groups in terms of eosinophil and basophil values (p<0.05). CONCLUSION: The number of eosinophils and basophils increased in patients with bronchopulmonary dysplasia without an increase in the number of leukocytes.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79728603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Gur, E. S. Gulec, Sadik Ince, M. Keskin, A. Demir, Baris Sengul, Mehmet Serkan Gur
OBJECTIVE: The study aimed to assess the association between the separate anthropometric indexes including visceral adiposity and metabolic syndrome on male fertility. STUDY DESIGN: In a cross-sectional study, the visceral and subcutaneous fat thickness of 162 participants were measured by ultrasonography. Participants' body mass index, waist circumference, and waist/hip ratio were determined. Participants' biochemical metabolic parameters and reproductive hormones were measured and semen parameters were recorded. Participants were divided into groups according to body mass index and different percentiles of the visceral fat thickness. Differences between groups were investigated by One-way ANOVA, Kruskal-Wallis H, and Pearson Chi-Square test. The relationship between anthropometric measurements and sperm parameters was evaluated by Pearson and Spearman’s rank correlation test. The effect of anthropometric indexes on sperm parameters was evaluated using multivariate regression analysis. RESULTS: It was seen that only total testosterone of sex hormones decreased significantly in the obesity group (p=0.003). There was a significant and reverse association between visceral fat thickness with sperm morphology (rho=–0.2, p=0.01). There was no significant correlation between semen parameters and other anthropometric measurements. In multiple regression analysis, the effect of anthropometric measurements, including visceral fat thickness, on semen parameters was not found, but only smoking was found to be a factor affecting sperm concentration, progressive motility, and morphology (p=0.03, p=0.03, and p=0.01). CONCLUSION: In this study, it was shown that increased obesity was associated with low testosterone levels and increased visceral fat was associated with abnormal sperm morphology. More extensive studies are required on this subject.
{"title":"Impact of Obesity, Visceral Adiposity and Metabolic Syndrome on Male Fertility","authors":"E. Gur, E. S. Gulec, Sadik Ince, M. Keskin, A. Demir, Baris Sengul, Mehmet Serkan Gur","doi":"10.21613/GORM.2021.1156","DOIUrl":"https://doi.org/10.21613/GORM.2021.1156","url":null,"abstract":"OBJECTIVE: The study aimed to assess the association between the separate anthropometric indexes including visceral adiposity and metabolic syndrome on male fertility. STUDY DESIGN: In a cross-sectional study, the visceral and subcutaneous fat thickness of 162 participants were measured by ultrasonography. Participants' body mass index, waist circumference, and waist/hip ratio were determined. Participants' biochemical metabolic parameters and reproductive hormones were measured and semen parameters were recorded. Participants were divided into groups according to body mass index and different percentiles of the visceral fat thickness. Differences between groups were investigated by One-way ANOVA, Kruskal-Wallis H, and Pearson Chi-Square test. The relationship between anthropometric measurements and sperm parameters was evaluated by Pearson and Spearman’s rank correlation test. The effect of anthropometric indexes on sperm parameters was evaluated using multivariate regression analysis. RESULTS: It was seen that only total testosterone of sex hormones decreased significantly in the obesity group (p=0.003). There was a significant and reverse association between visceral fat thickness with sperm morphology (rho=–0.2, p=0.01). There was no significant correlation between semen parameters and other anthropometric measurements. In multiple regression analysis, the effect of anthropometric measurements, including visceral fat thickness, on semen parameters was not found, but only smoking was found to be a factor affecting sperm concentration, progressive motility, and morphology (p=0.03, p=0.03, and p=0.01). CONCLUSION: In this study, it was shown that increased obesity was associated with low testosterone levels and increased visceral fat was associated with abnormal sperm morphology. More extensive studies are required on this subject.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84410187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Dey, Sanjay Singh, R. Tiwari, V. Nair, D. Arora, S. Tiwari
OBJECTIVES: Suppressed immune system and physiological changes in pregnancy put pregnant women vulnerable to various viral diseases. Various studies have reported adverse pregnancy outcomes in SARS-CoV-2 infection. This study aimed to evaluate the maternal and fetal outcomes in SARS-CoV-2 affected pregnancies at our set up. STUDY DESIGN: It was a prospective cohort study conducted at a tertiary care Army Hospital, India. The first 50 cases of SARS CoV-2 positive pregnant women and 144 suspected cases that were found SARS-CoV-2 negative, received and managed at separate set up, during a period extending from 01 April 2020 to 15 Sep 2020 were included in our study. Their obstetric and neonatal outcomes along with the demographic and other clinical data were compared. RESULTS: Total RT-PCR positivity rate of SARS-CoV-2 infection in pregnant women was 2.7%. 96% of our patients were asymptomatic for SARS-CoV-2 infection. Premature rupture of membrane, preterm delivery, and NICU admission was similar in both groups. There were increased incidences (70%) of cesarean section in SARS-CoV-2 positive pregnant women. CONCLUSION: The study reported comparable maternal and fetal outcomes in SARS-CoV 2 positive pregnant women when compared with SARS-CoV-2 negative pregnant women.
{"title":"Pregnancy Outcome in First 50 Sars-Cov-2 Positive Patients At Our Center","authors":"M. Dey, Sanjay Singh, R. Tiwari, V. Nair, D. Arora, S. Tiwari","doi":"10.21613/GORM.2021.1176","DOIUrl":"https://doi.org/10.21613/GORM.2021.1176","url":null,"abstract":"OBJECTIVES: Suppressed immune system and physiological changes in pregnancy put pregnant women vulnerable to various viral diseases. Various studies have reported adverse pregnancy outcomes in SARS-CoV-2 infection. This study aimed to evaluate the maternal and fetal outcomes in SARS-CoV-2 affected pregnancies at our set up.\u0000STUDY DESIGN: It was a prospective cohort study conducted at a tertiary care Army Hospital, India. The first 50 cases of SARS CoV-2 positive pregnant women and 144 suspected cases that were found SARS-CoV-2 negative, received and managed at separate set up, during a period extending from 01 April 2020 to 15 Sep 2020 were included in our study. Their obstetric and neonatal outcomes along with the demographic and other clinical data were compared.\u0000RESULTS: Total RT-PCR positivity rate of SARS-CoV-2 infection in pregnant women was 2.7%. 96% of our patients were asymptomatic for SARS-CoV-2 infection. Premature rupture of membrane, preterm delivery, and NICU admission was similar in both groups. There were increased incidences (70%) of cesarean section in SARS-CoV-2 positive pregnant women. \u0000CONCLUSION: The study reported comparable maternal and fetal outcomes in SARS-CoV 2 positive pregnant women when compared with SARS-CoV-2 negative pregnant women.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77298310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Ozkaya, E. Cogendez, Elif Tozkır, S. Unsal, A. Yavuz, Gülden Tunalı, O. Uzun, E. Ergen, S. Eser
OBJECTIVE: This study aimed to compare cycle outcomes among women with endometrioma or nonfunctional cysts versus control. STUDY DESIGN: Women under 35 years of age with unexplained infertility underwent in vitro fertilization cycle. Two hundred and ninety-nine women were included in this study. Study groups consist of women with endometrioma (n=82) or non-functional ovarian cysts (n=100) and control group (n=117). Women in each group were selected consecutively. Groups were matched for age and ovarian reserve and compared in terms of in vitro fertilization cycle outcome. RESULTS: There were no significant differences among groups in terms of mean age, early follicular phase Follicle-Stimulating Hormone, and anti-müllerian hormone levels (p>0.05). Baseline total antral follicle counts were similar among groups (p>0.05). There were significant differences among groups in terms of mean starting and total gonadotropin dose, peak estradiol level, total oocyte number, and mature oocyte numbers (p<0.05). Clinical pregnancy rates were 10.7%, 17.3%, and 31.6% in groups with non-functional cyst, endometrioma and control group respectively (p<0.05). The presence of a non-functional cystic mass of ovary on the starting day of stimulation was a risk factor for poor cycle outcome in terms of clinical pregnancy rates [OR=0.5 (95 % CI; 0.2-0.9, p=0.03)]. CONCLUSION: Our data showed that the presence of any kind of cystic mass of the ovary especially the non-functional cysts on the starting day of stimulation was a risk factor for poor cycle outcomes in terms of clinical pregnancy rates.
{"title":"Comparison of Cycle Outcomes Among Women with Endometrioma or Non-Functional Cysts Versus Control","authors":"E. Ozkaya, E. Cogendez, Elif Tozkır, S. Unsal, A. Yavuz, Gülden Tunalı, O. Uzun, E. Ergen, S. Eser","doi":"10.21613/GORM.2020.1110","DOIUrl":"https://doi.org/10.21613/GORM.2020.1110","url":null,"abstract":"OBJECTIVE: This study aimed to compare cycle outcomes among women with endometrioma or nonfunctional cysts versus control. STUDY DESIGN: Women under 35 years of age with unexplained infertility underwent in vitro fertilization cycle. Two hundred and ninety-nine women were included in this study. Study groups consist of women with endometrioma (n=82) or non-functional ovarian cysts (n=100) and control group (n=117). Women in each group were selected consecutively. Groups were matched for age and ovarian reserve and compared in terms of in vitro fertilization cycle outcome. RESULTS: There were no significant differences among groups in terms of mean age, early follicular phase Follicle-Stimulating Hormone, and anti-müllerian hormone levels (p>0.05). Baseline total antral follicle counts were similar among groups (p>0.05). There were significant differences among groups in terms of mean starting and total gonadotropin dose, peak estradiol level, total oocyte number, and mature oocyte numbers (p<0.05). Clinical pregnancy rates were 10.7%, 17.3%, and 31.6% in groups with non-functional cyst, endometrioma and control group respectively (p<0.05). The presence of a non-functional cystic mass of ovary on the starting day of stimulation was a risk factor for poor cycle outcome in terms of clinical pregnancy rates [OR=0.5 (95 % CI; 0.2-0.9, p=0.03)]. CONCLUSION: Our data showed that the presence of any kind of cystic mass of the ovary especially the non-functional cysts on the starting day of stimulation was a risk factor for poor cycle outcomes in terms of clinical pregnancy rates.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79129133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ö. Demir, Miraç Özalp, T. Aran, M. A. Osmanağaoğlu
OBJECTIVE: Vulvar lesions are not well known to gynecologists and often cause difficulties in the differential diagnosis. In this study; we aimed to show the frequency of pathologic diagnosis of vulvar lesions and their relationship with vulvar pruritus. STUDY DESIGN: The pathological results of the patients who underwent vulvar biopsy between 2015 and 2019 were examined. The frequency of vulvar lesions was determined and classified under certain headings for gynecologists. The pathological diagnoses were correlated with the severity of pruritus. RESULTS: A total of 220 patients underwent a vulvar biopsy between the dates indicated in the study. The mean age of these patients was 47.9±16.7. The most common concomitant lesion was vulvar pruritus with a rate of 62.7% in cases who were referred to the outpatient clinic and referred for vulvar biopsy. According to biopsy results, the three most common pathological diagnoses were proliferative lesions, infection, and dermatoses. Dermatoses were the most common pathologic diagnosis in patients with severe pruritus. CONCLUSION: Thanks to the clear classification of vulvar lesions for gynecologists; pathological diagnoses will not be overlooked and differential diagnoses will be more effective. In vulvar lesions accompanied by pruritus, making the differential diagnosis according to the severity of pruritus and bringing the possible diagnosis to mind first will speed up the treatment.
{"title":"Evaluation of the Frequency and Pathological Diagnosis of Vulvar Lesions Is it Associated with Vulvar Pruritus - If So, How Closely?","authors":"Ö. Demir, Miraç Özalp, T. Aran, M. A. Osmanağaoğlu","doi":"10.21613/GORM.2020.1152","DOIUrl":"https://doi.org/10.21613/GORM.2020.1152","url":null,"abstract":"OBJECTIVE: Vulvar lesions are not well known to gynecologists and often cause difficulties in the differential diagnosis. In this study; we aimed to show the frequency of pathologic diagnosis of vulvar lesions and their relationship with vulvar pruritus.\u0000STUDY DESIGN: The pathological results of the patients who underwent vulvar biopsy between 2015 and 2019 were examined. The frequency of vulvar lesions was determined and classified under certain headings for gynecologists. The pathological diagnoses were correlated with the severity of pruritus.\u0000RESULTS: A total of 220 patients underwent a vulvar biopsy between the dates indicated in the study. The mean age of these patients was 47.9±16.7. The most common concomitant lesion was vulvar pruritus with a rate of 62.7% in cases who were referred to the outpatient clinic and referred for vulvar biopsy. According to biopsy results, the three most common pathological diagnoses were proliferative lesions, infection, and dermatoses. Dermatoses were the most common pathologic diagnosis in patients with severe pruritus.\u0000CONCLUSION: Thanks to the clear classification of vulvar lesions for gynecologists; pathological diagnoses will not be overlooked and differential diagnoses will be more effective. In vulvar lesions accompanied by pruritus, making the differential diagnosis according to the severity of pruritus and bringing the possible diagnosis to mind first will speed up the treatment.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79795745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-05DOI: 10.21203/rs.3.rs-137296/v1
Kidist Gizachew, Betregiorgis Hailu Zegeye, T. Getinet
Background: Birth companion refers to a person who provides support to laboring women during child birth. Various studies have shown the benefits of birth companions. The objective of this study was to assess the attitude of mothers towards the involvement of birth companions during child birth at St Paul’s Hospital Millennium Medical College (SPHMMC) and its selected catchment health centers. Methodology: The study used a cross-sectional study to determine the perception of postpartum mothers on the involvement of birth companions during child birth. Result: The study included a total of 393 postpartum women. The finding from the study showed majority of the post-partum women (98.7%) were not allowed to have companions during labor. Among postpartum women 27.3 % has negative attitude towards involvement of birth companions. The commonest reasons mentioned by post-partum women for having negative attitude to this practice included need for privacy, religious values and fear of overburdening family members with stress. Conclusion: The findings from this study showed that majority of women were denied the option of having a birth companion. The study has also shown the desire to have birth companion isn’t universal among laboring women in our setup. There is a need to understand the socio-cultural values of the community before embarking on widespread implementation of involvement of birth companions.
{"title":"Perception of Post-partum Women Towards Birth Companions at a Tertiary Hospital and Its Catchment Health Centers in Addis Ababa, Ethiopia","authors":"Kidist Gizachew, Betregiorgis Hailu Zegeye, T. Getinet","doi":"10.21203/rs.3.rs-137296/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-137296/v1","url":null,"abstract":"\u0000 Background: Birth companion refers to a person who provides support to laboring women during child birth. Various studies have shown the benefits of birth companions. The objective of this study was to assess the attitude of mothers towards the involvement of birth companions during child birth at St Paul’s Hospital Millennium Medical College (SPHMMC) and its selected catchment health centers. Methodology: The study used a cross-sectional study to determine the perception of postpartum mothers on the involvement of birth companions during child birth. Result: The study included a total of 393 postpartum women. The finding from the study showed majority of the post-partum women (98.7%) were not allowed to have companions during labor. Among postpartum women 27.3 % has negative attitude towards involvement of birth companions. The commonest reasons mentioned by post-partum women for having negative attitude to this practice included need for privacy, religious values and fear of overburdening family members with stress. Conclusion: The findings from this study showed that majority of women were denied the option of having a birth companion. The study has also shown the desire to have birth companion isn’t universal among laboring women in our setup. There is a need to understand the socio-cultural values of the community before embarking on widespread implementation of involvement of birth companions.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86918602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahlam Ali Saif Al Hinai, Abdulrahman Al Farsi, Safa Khalfan Said Al Kitani, Rajaa Mohammed Salim Al, Hadrami
The aim of this study is to determine whether young adolescents aged 11-19 years have an increased risk of cesarean or operative delivery, as well as maternal or neonatal delivery-related morbidity, compared to young adults aged 20- 24 years in the tertiary hospital Royal Hospital in period from January 2006 to December 2015. It is a retrospective cohort study and we include all women delivered in royal hospital in that period of time and aged from 14 to 25 years and gestational age more than 24 week’s singleton pregnancy and cephalic presentation during labour. We exclude maternal Age > 25 years and Gestation age ≤24 weeks, Non-cephalic presentation and Multiple pregnancy. By this study, there is no significant outcome complication among adolescent age group pregnancy compare to adult group except IUGR and NICU admissions.
{"title":"Obstetric Outcome in Adolescents-(A Single Centre Experience Over 10 Years from Jan 2006-Dec 2015)","authors":"Ahlam Ali Saif Al Hinai, Abdulrahman Al Farsi, Safa Khalfan Said Al Kitani, Rajaa Mohammed Salim Al, Hadrami","doi":"10.33140/jgrm.05.01.02","DOIUrl":"https://doi.org/10.33140/jgrm.05.01.02","url":null,"abstract":"The aim of this study is to determine whether young adolescents aged 11-19 years have an increased risk of cesarean or operative delivery, as well as maternal or neonatal delivery-related morbidity, compared to young adults aged 20- 24 years in the tertiary hospital Royal Hospital in period from January 2006 to December 2015. It is a retrospective cohort study and we include all women delivered in royal hospital in that period of time and aged from 14 to 25 years and gestational age more than 24 week’s singleton pregnancy and cephalic presentation during labour. We exclude maternal Age > 25 years and Gestation age ≤24 weeks, Non-cephalic presentation and Multiple pregnancy. By this study, there is no significant outcome complication among adolescent age group pregnancy compare to adult group except IUGR and NICU admissions.","PeriodicalId":93778,"journal":{"name":"Journal of gynecology, clinical obstetrics and reproductive medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87099214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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