Electrical stimulation and microneedle-mediated drug delivery emerge as promising therapies in gastrointestinal (GI) motility disorders and inflammatory conditions. However, on-demand intervention therapy in enclosed narrow GI remains a challenge. Herein, a magnetic-driven soft membrane robot is presented that synergistically combines microneedle-mediated electrical stimulation and drug delivery. The membrane robot's bipolar magnetization enables switching between two surfaces by external magnetic fields, where N-pole drives treatment surface with microneedle to penetrate GI wall and S-pole initiates smooth surface for low resistance locomotion. The membrane robot utilizes magnetically coupled resonant wireless transmission to enable regulated electrical stimulation with 86.7% efficiency at 6 cm distance, while providing tunable voltage (0–20 V) and programmable pulse waveforms (0.4–50 ms width) for adaptive bioelectrical modulation. The drug-loaded microneedle array serves dual roles as both a penetrating electrode and a therapeutic interface, delivering electrical stimulation while simultaneously releasing encapsulated agents upon tissue penetration. In vitro experiments of the multimode motion and multifunctional treatment are validated in a fresh pig gut. This integrated membrane magnetic robot offers great potential in GI diagnostics, personalized neuromodulation, and on-demand drug release applications.
{"title":"Wirelessly Powered Soft Magnetic Robot with Microneedle for Electrical Stimulation and Drug Delivery","authors":"Song Zhao, Liwen Zhang, Shengbin Zhang, Botao Ma, Meng Wang, Yipan Zuo, Xinzhao Zhou, Xueshan Jing, Huawei Chen","doi":"10.1002/aisy.202500382","DOIUrl":"https://doi.org/10.1002/aisy.202500382","url":null,"abstract":"<p>Electrical stimulation and microneedle-mediated drug delivery emerge as promising therapies in gastrointestinal (GI) motility disorders and inflammatory conditions. However, on-demand intervention therapy in enclosed narrow GI remains a challenge. Herein, a magnetic-driven soft membrane robot is presented that synergistically combines microneedle-mediated electrical stimulation and drug delivery. The membrane robot's bipolar magnetization enables switching between two surfaces by external magnetic fields, where N-pole drives treatment surface with microneedle to penetrate GI wall and S-pole initiates smooth surface for low resistance locomotion. The membrane robot utilizes magnetically coupled resonant wireless transmission to enable regulated electrical stimulation with 86.7% efficiency at 6 cm distance, while providing tunable voltage (0–20 V) and programmable pulse waveforms (0.4–50 ms width) for adaptive bioelectrical modulation. The drug-loaded microneedle array serves dual roles as both a penetrating electrode and a therapeutic interface, delivering electrical stimulation while simultaneously releasing encapsulated agents upon tissue penetration. In vitro experiments of the multimode motion and multifunctional treatment are validated in a fresh pig gut. This integrated membrane magnetic robot offers great potential in GI diagnostics, personalized neuromodulation, and on-demand drug release applications.</p>","PeriodicalId":93858,"journal":{"name":"Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)","volume":"8 2","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/aisy.202500382","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146217484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Heterogeneous multirobot systems show great potential in complex tasks requiring coordinated hybrid cooperation. However, existing methods that rely on static or task-specific models often lack generalizability across diverse tasks and dynamic environments. This highlights the need for generalizable intelligence that can bridge high-level reasoning with low-level execution across heterogeneous agents. To address this, a hierarchical multimodal framework that integrates a prompted large language model (LLM) with a fine-tuned vision-language model (VLM) is proposed. At the system level, the LLM performs hierarchical task decomposition and constructs a global semantic map, while the VLM provides semantic perception and object localization, where the proposed GridMask significantly enhances the VLM's spatial accuracy for reliable fine-grained manipulation. The aerial robot leverages this global map to generate semantic paths and guide the ground robot's local navigation and manipulation, ensuring robust coordination even in target-absent or ambiguous scenarios. The framework is validated through extensive simulation and real-world experiments on long-horizon object arrangement tasks, demonstrating zero-shot adaptability, robust semantic navigation, and reliable manipulation in dynamic environments. To the best of our knowledge, this work presents the first heterogeneous aerial–ground robotic system that integrates VLM-based perception with LLM-driven reasoning for global high-level task planning and execution.
{"title":"Hierarchical Language Models for Semantic Navigation and Manipulation in an Aerial-Ground Robotic System","authors":"Haokun Liu, Zhaoqi Ma, Yunong Li, Junichiro Sugihara, Yicheng Chen, Jinjie Li, Moju Zhao","doi":"10.1002/aisy.202500640","DOIUrl":"https://doi.org/10.1002/aisy.202500640","url":null,"abstract":"<p>Heterogeneous multirobot systems show great potential in complex tasks requiring coordinated hybrid cooperation. However, existing methods that rely on static or task-specific models often lack generalizability across diverse tasks and dynamic environments. This highlights the need for generalizable intelligence that can bridge high-level reasoning with low-level execution across heterogeneous agents. To address this, a hierarchical multimodal framework that integrates a prompted large language model (LLM) with a fine-tuned vision-language model (VLM) is proposed. At the system level, the LLM performs hierarchical task decomposition and constructs a global semantic map, while the VLM provides semantic perception and object localization, where the proposed GridMask significantly enhances the VLM's spatial accuracy for reliable fine-grained manipulation. The aerial robot leverages this global map to generate semantic paths and guide the ground robot's local navigation and manipulation, ensuring robust coordination even in target-absent or ambiguous scenarios. The framework is validated through extensive simulation and real-world experiments on long-horizon object arrangement tasks, demonstrating zero-shot adaptability, robust semantic navigation, and reliable manipulation in dynamic environments. To the best of our knowledge, this work presents the first heterogeneous aerial–ground robotic system that integrates VLM-based perception with LLM-driven reasoning for global high-level task planning and execution.</p>","PeriodicalId":93858,"journal":{"name":"Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)","volume":"8 2","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/aisy.202500640","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146680577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yibo He, Kah Phooi Seng, Chee Shen Lim, Li Minn Ang
Dysarthric speech recognition faces significant challenges of acoustic variability and data scarcity, and this study proposes a robust system by integrating generative adversarial network enhancement and large language model correction to address these issues effectively. The system employs three key components, including a multimodal recognition core that combines whisper-medium encoder with LoRA-fine-tuned Llama-3.1-8B for end-to-end acoustic-to-semantic mapping, an improved CycleGAN module that generates synthetic dysarthric speech through Inception-ResNet fusion blocks, and an intelligent error correction mechanism using N-best hypothesis reranking with semantic constraints. Experiments on the UA-Speech dataset show that the complete system achieves a 20.61% word error rate representing a 73.9% relative improvement over traditional end-to-end transformer automatic speech recognition. Under very low intelligibility conditions it maintains a 48.69% word error rate demonstrating robust recognition for severe pathological speech. Ablation studies validate each module's effectiveness, providing significant advances for dysarthric patient communication technologies.
{"title":"Robust Dysarthric Speech Recognition with GAN Enhancement and LLM Correction","authors":"Yibo He, Kah Phooi Seng, Chee Shen Lim, Li Minn Ang","doi":"10.1002/aisy.202500873","DOIUrl":"https://doi.org/10.1002/aisy.202500873","url":null,"abstract":"<p>Dysarthric speech recognition faces significant challenges of acoustic variability and data scarcity, and this study proposes a robust system by integrating generative adversarial network enhancement and large language model correction to address these issues effectively. The system employs three key components, including a multimodal recognition core that combines whisper-medium encoder with LoRA-fine-tuned Llama-3.1-8B for end-to-end acoustic-to-semantic mapping, an improved CycleGAN module that generates synthetic dysarthric speech through Inception-ResNet fusion blocks, and an intelligent error correction mechanism using N-best hypothesis reranking with semantic constraints. Experiments on the UA-Speech dataset show that the complete system achieves a 20.61% word error rate representing a 73.9% relative improvement over traditional end-to-end transformer automatic speech recognition. Under very low intelligibility conditions it maintains a 48.69% word error rate demonstrating robust recognition for severe pathological speech. Ablation studies validate each module's effectiveness, providing significant advances for dysarthric patient communication technologies.</p>","PeriodicalId":93858,"journal":{"name":"Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)","volume":"8 2","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/aisy.202500873","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146217442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaeweon Kang, Johyeon Kim, Sueyeon Kim, Hyunbo Cho, Jongwook Jeon
This article proposes a neural network-based parameter extraction methodology for the Berkeley Short-Channel IGFET Model–Common Multi-Gate (BSIM–CMG) model applied to gate-all-around field effect transistors (GAAFETs), capturing both current–voltage and capacitance–voltage characteristics to support compact model library development. Conventional BSIM parameter extraction is often complex and inefficient, requiring manual intervention and significant time to cover a wide range of device dimensions and temperatures. To address these limitations, a novel binning adaptive sampling strategy is integrated into the neural network-based extraction framework to efficiently generate training data across broad device dimension ranges. In addition, the transformer-based deep neural networks are designed to output only binnable parameters, ensuring compatibility with compact model library requirements. The trained networks are tested using 3 nm node GAAFET Technology Computer Aided Design (TCAD) data under various conditions, achieving mean absolute percentage errors below 5% for both drain current and gate capacitance. Consequently, the extracted parameters are integrated with corner model parameters through binning equations. This approach results in binning models that are readily deployable in compact model libraries while significantly reducing parameter extraction time and enabling automation across a wide range of GAAFET dimensions.
{"title":"Machine Learning-Based Standard Compact Model Binning Parameter Extraction Methodology for Integrated Circuit Design of Next-Generation Semiconductor Devices","authors":"Jaeweon Kang, Johyeon Kim, Sueyeon Kim, Hyunbo Cho, Jongwook Jeon","doi":"10.1002/aisy.202500511","DOIUrl":"https://doi.org/10.1002/aisy.202500511","url":null,"abstract":"<p>This article proposes a neural network-based parameter extraction methodology for the Berkeley Short-Channel IGFET Model–Common Multi-Gate (BSIM–CMG) model applied to gate-all-around field effect transistors (GAAFETs), capturing both current–voltage and capacitance–voltage characteristics to support compact model library development. Conventional BSIM parameter extraction is often complex and inefficient, requiring manual intervention and significant time to cover a wide range of device dimensions and temperatures. To address these limitations, a novel binning adaptive sampling strategy is integrated into the neural network-based extraction framework to efficiently generate training data across broad device dimension ranges. In addition, the transformer-based deep neural networks are designed to output only binnable parameters, ensuring compatibility with compact model library requirements. The trained networks are tested using 3 nm node GAAFET Technology Computer Aided Design (TCAD) data under various conditions, achieving mean absolute percentage errors below 5% for both drain current and gate capacitance. Consequently, the extracted parameters are integrated with corner model parameters through binning equations. This approach results in binning models that are readily deployable in compact model libraries while significantly reducing parameter extraction time and enabling automation across a wide range of GAAFET dimensions.</p>","PeriodicalId":93858,"journal":{"name":"Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)","volume":"8 2","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/aisy.202500511","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146217485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fiheon Imroze, Bhavani Yalagala, Naveen Kumar, Mostafa Elsayed, Meraj Ahmad, Robert Graham, Vihar Georgiev, Hadi Heidari, Martin Weides
With the advancement of artificial intelligence (AI), there is an increasing demand for high-speed, energy-efficient hardware capable of running complex machine learning algorithms. Traditional hardware is constrained by the Von Neumann bottleneck, resulting in high power consumption and slower speeds. Inspired by the human brain, bio-mimicking the dynamic synaptic plasticity of the biological synapse using synaptic transistors is crucial to building the next generation of high-performance computing hardware-based neural networks. This study investigates neuromorphic behavior in 180 nm bulk complementary metal oxide semiconductor (CMOS) devices at 4 K, emphasizing memory properties and synapse-like characteristics. These findings position bulk CMOS as a scalable, energy-efficient, cryo-compatible platform for neuromorphic and quantum computing use. Gated-pulse measurements are used to study potentiation–depression behavior by quantifying conductance changes as functions of pulse amplitude and width. These results closely resemble biological synaptic plasticity, laying the groundwork for integrating cryo-CMOS technology into neuromorphic computing. The work reported here aims to work toward the development of hybrid computational systems by bridging the gap between conventional CMOS devices and emerging cryogenic technology, offering new avenues for scalable, energy-efficient, and high-performance cryogenic neuromorphic technologies.
{"title":"Cryogenic Neuromorphic Synaptic Behavior in 180 nm Silicon Transistors for Emerging Computing Systems","authors":"Fiheon Imroze, Bhavani Yalagala, Naveen Kumar, Mostafa Elsayed, Meraj Ahmad, Robert Graham, Vihar Georgiev, Hadi Heidari, Martin Weides","doi":"10.1002/aisy.202500506","DOIUrl":"https://doi.org/10.1002/aisy.202500506","url":null,"abstract":"<p>With the advancement of artificial intelligence (AI), there is an increasing demand for high-speed, energy-efficient hardware capable of running complex machine learning algorithms. Traditional hardware is constrained by the Von Neumann bottleneck, resulting in high power consumption and slower speeds. Inspired by the human brain, bio-mimicking the dynamic synaptic plasticity of the biological synapse using synaptic transistors is crucial to building the next generation of high-performance computing hardware-based neural networks. This study investigates neuromorphic behavior in 180 nm bulk complementary metal oxide semiconductor (CMOS) devices at 4 K, emphasizing memory properties and synapse-like characteristics. These findings position bulk CMOS as a scalable, energy-efficient, cryo-compatible platform for neuromorphic and quantum computing use. Gated-pulse measurements are used to study potentiation–depression behavior by quantifying conductance changes as functions of pulse amplitude and width. These results closely resemble biological synaptic plasticity, laying the groundwork for integrating cryo-CMOS technology into neuromorphic computing. The work reported here aims to work toward the development of hybrid computational systems by bridging the gap between conventional CMOS devices and emerging cryogenic technology, offering new avenues for scalable, energy-efficient, and high-performance cryogenic neuromorphic technologies.</p>","PeriodicalId":93858,"journal":{"name":"Advanced intelligent systems (Weinheim an der Bergstrasse, Germany)","volume":"8 2","pages":""},"PeriodicalIF":6.1,"publicationDate":"2025-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/aisy.202500506","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146217486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The cover illustrates a gregarious locust interacting with a biomimetic agent inoculated with Beauveria bassiana on an robotic experimental platform, highlighting the dynamics of social immunity and pathogen information spread within the swarm, as explored through innovative biohybrid method of this study. More details can be found in article 2400763 by Donato Romano and Cesare Stefanini.