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Acute macular neuroretinopathy associated with migraine 与偏头痛有关的急性黄斑神经视网膜病变。
Pub Date : 2025-01-01 DOI: 10.1016/j.oftale.2024.10.010
N. Domènech-López , V. Llorenç , A. Moll-Udina , A. Adán
Acute macular neuroretinopathy (AMN) is an uncommon entity that affects the outer layer of the retina and usually presents itself as an acute paracentral scotoma. It is mostly seen in young women and the course is usually self-limited. The diagnosis is established by a multimodal image, with optical coherence tomography (OCT) being the preferred technique. The origin is thought to be linked to a possible dysregulation in the flow of the deep vascular plexus of the retina or the choriocapillaris. A clinical case of an AMN in a young woman associated with a migraine attack is presented, highlighting the importance of considering this disease in the differential diagnosis of visual disorders associated with migraines. A physiological and pathological basis between migraine and NMA is suggested.
急性黄斑神经视网膜病变(AMN)是一种不常见的视网膜外层病变,通常表现为急性旁中心性黑矇。它主要见于年轻女性,病程通常是自限性的。诊断需要通过多模态图像来确定,光学相干断层扫描(OCT)是首选技术。其起源被认为与视网膜深层血管丛或绒毛膜的血流可能失调有关。本文介绍了一例年轻女性偏头痛发作时出现视网膜睫状体异常的临床病例,强调了在鉴别诊断与偏头痛有关的视觉障碍时考虑这种疾病的重要性。本文提出了偏头痛与 NMA 之间的生理和病理基础。
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引用次数: 0
First Reported Case of atypical Cogan's Syndrome in Central America 中美洲首例报告的非典型科根综合征病例。
Pub Date : 2025-01-01 DOI: 10.1016/j.oftale.2024.08.005
L.M. Vindel Valle , M.A. López Alfaro

Case report

Case report of a 51 year old patient diagnosed with atypical Cogan's syndrome. The patient exhibited interstitial keratitis, anterior uveitis, and long-standing profound deafness. The treatment was based on topical and systemic steroids, resulting in a satisfactory evolution and currently in clinical remission.

Discussion

Cogan's syndrome is a chronic inflammatory disease that has existed for over 60 years. Because its diagnosis is purely clinical, not many cases have been reported worldwide. Therefore, it is important to be aware of this condition to make a quick diagnosis and provide multidisciplinary treatment, thus preventing irreversible complications.
病例报告:病例报告:一名 51 岁的患者被诊断为非典型科根综合征。患者表现为间质性角膜炎、前葡萄膜炎和长期重度耳聋。患者接受了局部和全身类固醇治疗,病情得到了满意的控制,目前临床症状有所缓解:讨论:科根综合征是一种慢性炎症性疾病,已有 60 多年的历史。由于该病的诊断纯粹依靠临床表现,因此世界范围内报道的病例并不多。因此,了解这种疾病对快速诊断和提供多学科治疗非常重要,从而防止出现不可逆转的并发症。
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引用次数: 0
Frequency, risk factors and time to resolution of exposure keratopathy in patients in the Pediatric Intensive Care Unit 儿科重症监护室患者暴露性角膜病的发病率、风险因素和缓解时间。
Pub Date : 2025-01-01 DOI: 10.1016/j.oftale.2024.10.011
R.A. Pech-Lugo , A. Vázquez-Cerón , F.K. Segura-López , A. Dávila-Camargo

Background and objective

Exposure keratopathy (EPK) is characterized by punctate erosions of the corneal epithelium, mainly located in the lower third of the cornea. In the Pediatric Intensive Care Unit (PICU), an incidence of 19–25 % has been reported. The objective of this study was to describe the frequency, risk factors, and time to resolution of exposure keratitis in PICU patients.

Materials and methods

Descriptive, observational, longitudinal, prospective study. The association of keratitis due to exposure to risk factors was evaluated using the Chi square test and determining the OR and 95% confidence interval.

Results

81 patients admitted to the PICU between March and September 2023 were included, 46 (56.79%) developed PEK, 67.39% (31/46) grade 1 and 26.08% (12/46) grade 3. The median time Resolution was 3 days, interquartile range (2–5). A significant difference was observed between patients with and without PEK in the requirement for mechanical ventilation 86.13% vs., 54.29% p = 0.01, OR = 6.905 (2.20−21.64), sedation 100% vs., 85.71%, p = 0.02, in the duration of sedation 5 days vs. 2.5 days (p = 0.024), neuromuscular relaxation 21.74% vs., 0%, p = 0.002, lagophthalmos 86.94% vs., 31.43% p < 0.00001, OR = 13.33 (4.42–40.17), chemosis 15.21% vs., 0%, p = 0.014 and days of stay in the PICU median 7 (5–11) vs. 3 (2–6), p < 0.00001.

Conclusions

The frequency of QPE observed was 56.79%, higher than that previously reported in the literature in the pediatric population. Mechanical ventilation, sedation, duration of sedation, Lagoftalmos chemosis and days of stay in the PICU were identified as risk factors.
背景和目的:暴露性角膜病(EPK)的特征是角膜上皮点状糜烂,主要位于角膜的下三分之一处。据报道,在儿科重症监护病房(PICU)中,其发病率为 19%-25%。本研究旨在描述儿科重症监护室患者暴露性角膜炎的发病频率、风险因素和缓解时间:描述性、观察性、纵向、前瞻性研究。研究结果:81 名 PICU 患者的暴露性角膜炎发生率与风险因素的相关性用智平方检验进行了评估,并确定了 OR 和 95% 的置信区间:研究纳入了 2023 年 3 月至 9 月期间入住 PICU 的 81 名患者,其中 46 人(56.79%)患 PEK,67.39%(31/46)为 1 级,26.08%(12/46)为 3 级。解救时间中位数为 3 天,四分位数间距(2-5)。在机械通气需求方面,86.13% 的患者与 54.29% 的患者之间存在明显差异,P = 0.01,OR = 6.905(2.20-21.64),镇静 100% 的患者与 85.71% 的患者之间存在明显差异,P = 0.02,镇静持续时间 5 天与 2.5 天之间存在明显差异(P = 0.024),神经肌肉松弛 21.74% 的患者与 0% 的患者之间存在明显差异,P = 0.002,Lagoftalmos 86.94% 的患者与 31.43% 的患者之间存在明显差异:观察到的 QPE 发生率为 56.79%,高于之前文献报道的儿科人群的发生率。机械通气、镇静、镇静持续时间、Lagoftalmos 化疗和在重症监护病房的住院天数被确定为风险因素。
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引用次数: 0
Cyclodestructive treatment for symptomatic intraocular pressure elevation during hemodialysis: case reports and literature review 血液透析期间症状性眼压升高的破环治疗:病例报告及文献复习。
Pub Date : 2025-01-01 DOI: 10.1016/j.oftale.2024.12.001
H. Mies , F. Manzur , S. Verdaguer D

Introduction

Within the characteristics of hypertensive glaucoma, it is distinguished by presenting elevated intraocular pressure (IOP) associated with a low ocular perfusion pressure (OPP). Changes in these parameters can be affected by systemic disease such chronic kidney disease (CKD). Likewise, there is a correlation in the prevalence of both pathologies in patients with similar characteristics, emphasizing the need to address glaucoma management in patients with CKD given the implications of the disease on ocular pathology. Furthermore, hemodialysis (HD) is the maintenance treatment for end-stage CKD, which can lead to transient increases in IOP contributing to ocular discomfort and potential glaucoma progression.

Methods

A search was conducted in PubMed and Epistemonikos databases, constructing a theoretical framework based on primary studies and similar case reports. Additionally, two cases of patients with CKD with severe ocular pain during HD are presented, compiling data from electronic medical records, including demographic data, clinical presentations, treatments, and post-treatment outcomes.

Results

Both patients received cyclodestructive treatment for symptomatic hypertensive glaucoma episodes during HD, showing favourable clinical outcomes after treatment, both in controlling IOP elevation and relieving ocular pain during hemodialysis sessions.

Discussion

This review sheds light on a relatively underexplored aspect of glaucoma treatment in CKD patients on HD, where cyclodiode laser therapy appears to be a promising option in cases where there is no recoverable visual acuity. However, since the evidence is still emerging, future prospective comparative studies are needed to provide further information to clinical practice.
简介:在高血压性青光眼的特征中,其特点是眼内压(IOP)升高伴低眼灌注压(OPP)。这些参数的变化可能受到全身性疾病如慢性肾脏疾病(CKD)的影响。同样,在具有相似特征的患者中,两种病理的患病率存在相关性,这强调了考虑到CKD对眼部病理的影响,有必要解决CKD患者青光眼的管理问题。此外,血液透析(HD)是终末期CKD的维持治疗,可导致短暂性IOP升高,导致眼部不适和潜在的青光眼进展。方法:检索PubMed和Epistemonikos数据库,根据初步研究和类似病例报告构建理论框架。此外,本文还报道了两例慢性肾病患者在HD期间伴有严重眼痛的病例,从电子病历中收集数据,包括人口统计数据、临床表现、治疗和治疗后结果。结果:两例患者均接受了HD期间症状性高血压性青光眼的环破坏治疗,治疗后的临床结果良好,在控制IOP升高和缓解血液透析期间的眼部疼痛方面均表现良好。讨论:本综述揭示了CKD合并HD患者青光眼治疗的一个相对未被充分探索的方面,其中环二极管激光治疗似乎是一个有希望的选择,在没有恢复视力的情况下。然而,由于证据仍在不断涌现,未来的前瞻性比较研究需要为临床实践提供进一步的信息。
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引用次数: 0
Acanthamoeba keratitis in the last decade. What have we learned? 过去十年中的阿卡阿米巴角膜炎。我们学到了什么?
Pub Date : 2025-01-01 DOI: 10.1016/j.oftale.2024.11.001
A. Arnaiz-Camacho , L. Goterris Bonet , L. Bisbe Lopez , S. Martín Nalda , J. Puig Galy , S. García-Hidalgo , T. Pablos-Jiménez , A. Pairó-Salvador

Introduction

Acanthamoeba keratitis continues to be one of the most feared corneal infections due to its severity and capacity to generate irreversible visual sequelae. Despite diagnostic and therapeutic advances, this disease is increasing in our environment every year, related to a growing number of contact lens users. This last decade marked by the COVID-19 pandemic represents an unprecedented historical scenario whose impact must be analyzed from different health points of view.
This study aims to describe the epidemiology, clinical presentation, treatment and evolution of Acanthamoeba keratitis in a tertiary hospital in the last 10 years.

Results

The results have been obtained from a total of 13 eyes of 13 patients. This series of cases shows a diagnostic gap during the pandemic period, with a greater number of patients in the previous and post-pandemic stages. The different parameters of clinical presentation, microbiological diagnosis and clinical evolution are analyzed. All patients in our study wore contact lenses. Five of the cases were initially diagnosed in other centers as herpetic keratitis. Seven patients had a pseudo-dendrite as initial presentation, while six cases presented as an annular infiltrate. In all cases, 0.02% chlorhexidine eye drops were prescribed and this was associated with 0.1% propamidine in 11 cases. The results were variable, achieving an improvement in visual acuity in 10 of the cases.

Conclusion

This is a study on an emerging disease and with increasingly advanced knowledge and use of diagnostic and therapeutic tools in the historical context of a pandemic. This text attempts to shed light on the different forms of presentation and management of cases of Acanthamoeba keratitis.
导言:阿卡阿米巴角膜炎因其严重性和产生不可逆视力后遗症的能力,仍然是最令人恐惧的角膜感染之一。尽管在诊断和治疗方面取得了进步,但这种疾病在我们的环境中每年都在增加,这与越来越多的隐形眼镜使用者有关。在过去的十年中,COVID-19 的流行代表了前所未有的历史场景,必须从不同的健康角度分析其影响。本研究旨在描述一家三级医院在过去 10 年中阿卡阿米巴角膜炎的流行病学、临床表现、治疗和演变情况:结果:共对 13 名患者的 13 只眼睛进行了检查。这一系列病例表明,在大流行期间存在诊断上的差距,而在大流行之前和之后阶段的患者人数较多。研究分析了临床表现、微生物诊断和临床演变的不同参数。我们研究的所有患者都佩戴隐形眼镜。其中五例最初在其他中心被诊断为疱疹性角膜炎。七名患者最初表现为假性树枝状角膜炎,六名患者表现为环状浸润。在所有病例中,都使用了 0.02% 洗必泰滴眼液,在 11 个病例中使用了 0.1% 丙脒滴眼液。结果不一,其中 10 例的视力有所改善:这是一项关于新兴疾病的研究,在大流行病的历史背景下,诊断和治疗工具的知识和使用日益先进。本文试图阐明阿卡阿米巴角膜炎病例的不同表现形式和治疗方法。
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引用次数: 0
Is research an ethical obligation for hospital and academic ophthalmologists? 研究是医院和学术眼科医生的道德义务吗?
Pub Date : 2024-12-26 DOI: 10.1016/j.oftale.2024.12.013
José Carlos Pastor, José A Fernández Vigo
{"title":"Is research an ethical obligation for hospital and academic ophthalmologists?","authors":"José Carlos Pastor, José A Fernández Vigo","doi":"10.1016/j.oftale.2024.12.013","DOIUrl":"10.1016/j.oftale.2024.12.013","url":null,"abstract":"","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraorbital rituximab to treat orbital inflammation in a patient with active neoplasia. 眼眶内美罗华治疗一例活动性肿瘤患者的眼眶炎症。
Pub Date : 2024-12-26 DOI: 10.1016/j.oftale.2024.12.015
P Rivera Pérez de Rada, M Cobas Belso, S Vallinas Hidalgo, A Ruibal Escribano, E Barastay Alberdi, M Benedí Alcivar

A 66-year-old woman presents with unilateral orbital inflammation of several years of evolution, initially classified as idiopathic orbital inflammatory disease (IOID) subtype myositis. She presented with pain, eyelid inflammation and significant elevation of intraocular pressure, as well as radiological signs of exophthalmos and superior rectus myositis. She was treated with corticosteroids, with partial response. She was diagnosed with colon adenocarcinoma, complicated with febrile neutropenia, and therefore immunosuppressive treatment was contraindicated. Treatment with intraorbital rituximab was decided, achieving resolution of symptoms and reduction of IOP. The diagnosis of neoplasia raises the possibility of paraneoplastic orbital inflammation.

66岁女性,单侧眼眶炎症发展数年,最初归类为特发性眼眶炎症(IOID)亚型肌炎。她表现为疼痛、眼睑炎症和眼压明显升高,以及突出眼和上直肌炎的影像学征象。她接受了皮质类固醇治疗,部分有效。她被诊断为结肠腺癌,并发发热性中性粒细胞减少症,因此免疫抑制治疗是禁忌。决定眼眶内使用利妥昔单抗治疗,症状得到缓解,IOP降低。肿瘤的诊断增加了副肿瘤眼眶炎症的可能性。
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引用次数: 0
Importance of individualized treatment: Subconjunctival device in silicone oil-induced glaucoma. 个体化治疗的重要性:结膜下装置治疗硅油性青光眼。
Pub Date : 2024-12-26 DOI: 10.1016/j.oftale.2024.12.017
J Avilés-Prieto, M Parrila-Vallejo, C Cortes-Laborda, P Molina-Solana, S Dominguez-Llamas, E Rodríguez-de-la-Rúa-Franch

Although silicone oil is used as an intraocular buffer in vitreoretinal surgical procedures, its use can cause complications, including glaucoma. This study highlights the importance of individualized approaches for the management of silicone oil-induced glaucoma. A 62-year-old man with a past medical history of retinal detachment and multiple ocular surgical procedurespresented with uncontrolled ocular pressure peaks after retinal detachment surgery using silicone oil as a buffer, which did not resolve after removal of the buffer. We decided to perform anterior chamber lavage followed by the implantation of a subconjunctival drainage device in the lower nasal location to minimize complications and maintain good visual acuity. Silicone oil extraction is usually the treatment of choice, although it can cause fluctuations in intraocular pressure. In this case, a more physiological and less invasive approach was chosen with the implantation of a Presserflo® device in the lower nasal region, avoiding complications and achieving the preoperative goals without uneventfully.

虽然硅油在玻璃体视网膜手术中被用作眼内缓冲剂,但它的使用会引起并发症,包括青光眼。本研究强调了个体化治疗硅油性青光眼的重要性。一名62岁男性,既往有视网膜脱离病史,多次眼部手术,在使用硅油作为缓冲液进行视网膜脱离手术后出现不受控制的眼压峰值,在取出缓冲液后仍未消退。我们决定先行前房灌洗,然后在下鼻位置植入结膜下引流装置,以减少并发症并保持良好的视力。硅油萃取通常是治疗的选择,尽管它会引起眼压波动。在本病例中,我们选择了一种更具生理性和更少侵入性的方法,在下鼻区植入Presserflo®装置,避免了并发症并顺利实现了术前目标。
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引用次数: 0
Multimodal imaging to detect retinal migration of perfluorocarbon liquid. 多模态成像检测全氟碳液体视网膜迁移。
Pub Date : 2024-12-26 DOI: 10.1016/j.oftale.2024.12.016
F J Valentín Bravo, K Castaño Andrés, X Valldeperas
{"title":"Multimodal imaging to detect retinal migration of perfluorocarbon liquid.","authors":"F J Valentín Bravo, K Castaño Andrés, X Valldeperas","doi":"10.1016/j.oftale.2024.12.016","DOIUrl":"10.1016/j.oftale.2024.12.016","url":null,"abstract":"","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of SICS (small incision cataract surgery) in humanitarian campaigns: Description of the surgical technique and review of the literature. 在人道主义运动中实施SICS(小切口白内障手术):手术技术的描述和文献综述。
Pub Date : 2024-12-26 DOI: 10.1016/j.oftale.2024.12.014
D Berrones, C Rocha-de-Lossada, E Barraquer-Compte, G Valvecchia, J Fernández

The aim of this article has been, on the one hand, to describe the use of MSICS (manual small incision cataract surgery) for the management of cataracts, especially mature ones, in relation to its particular utility in the field of humanitarian campaigns, for which a description of the MSICS technique has been made, subsequently a review of the available scientific literature has been carried out to verify the results of this technique in comparison with phacoemulsification and extracapsular surgery and to describe the importance of teaching this technique to all cataract surgeons, especially the ones participating in humanitarian campaigns. According to what has been found, MSICS is an excellent surgical technique and according to current evidence it seems to be the choice over phacoemulsification and/or the classic extracapsular technique in hyper mature cataracts, especially in the field of humanitarian campaigns, due to its lower rate of complications and the improvement in visual acuity obtained. According to the studies found, it would be possible for the experienced ophthalmologic surgeon to implement this technique since the learning curve is short. In addition, in the scenario of humanitarian campaigns, the cost per surgery and the surgical time are reduced. It can be concluded that MSICS should be part of the surgical repertoire of every cataract surgeon, especially in those who perform surgeries in humanitarian campaigns, since it provides shorter surgical time, lower cost and better results in complex cases.

这篇文章的目的,一方面是描述手工小切口白内障手术在治疗白内障,特别是成熟白内障方面的应用,以及它在人道主义运动领域的特殊用途,为此已对手工小切口白内障手术技术作了说明;随后,对现有的科学文献进行了回顾,以验证该技术与超声乳化术和囊外手术的结果,并描述了向所有白内障外科医生,特别是参与人道主义运动的外科医生教授该技术的重要性。根据所发现的,mscs是一种优秀的手术技术,根据目前的证据,它似乎是超成熟白内障的首选超声乳化术和/或经典的囊外技术,特别是在人道主义运动领域,由于其并发症发生率较低,视力得到改善。根据研究发现,由于学习曲线短,有经验的眼科医生可以实施这项技术。此外,在人道主义运动的情况下,每次手术的费用和手术时间都减少了。由此可以得出结论,mscs应该成为每个白内障外科医生的手术项目的一部分,特别是那些在人道主义运动中进行手术的人,因为它在复杂病例中提供了更短的手术时间、更低的成本和更好的结果。
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引用次数: 0
期刊
Archivos de la Sociedad Espanola de Oftalmologia
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