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Retinal detachment associated to macular hole in nanophthalmos and high hyperopia 纳米眼和高度远视与黄斑孔相关的视网膜脱离。
Pub Date : 2025-11-01 DOI: 10.1016/j.oftale.2025.08.004
A.L. Quiroz, P. Armendariz, J.D. Grigera
We report the case of a 74-year-old woman with high hyperopia and nanophthalmos who presented with a progressive central scotoma in her left eye. Best-corrected visual acuity was limited to hand motion, and examination revealed a full-thickness macular hole associated with retinal detachment. Pars plana vitrectomy with the inverted internal limiting membrane (ILM) flap technique and 20% sulfur hexafluoride (SF6) tamponade was performed, but hole closure was not achieved. A second surgery including phacovitrectomy, retinal massage and ILM flap repositioning resulted in successful anatomical closure and visual improvement. This case highlights the value of adjunctive techniques such as retinal massage and accurate ILM flap repositioning to promote closure in complex and uncommon scenarios.
我们报告的情况下,74岁的妇女高度远视和纳米眼谁提出了进行性中央暗斑在她的左眼。最佳矫正视力仅限于手部运动,检查发现全层黄斑孔伴视网膜脱离。采用倒内限制膜(ILM)皮瓣技术和20%六氟化硫(SF6)填塞术行玻璃体平面肌切除术,但未达到闭眼效果。第二次手术包括晶状体切除术,视网膜按摩和ILM瓣重新定位,成功地闭合了解剖和改善了视力。本病例强调了辅助技术的价值,如视网膜按摩和准确的ILM瓣重新定位,以促进复杂和罕见情况下的闭合。
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引用次数: 0
Role of light in myopia management: A citation network analysis 光在近视管理中的作用:引文网络分析。
Pub Date : 2025-11-01 DOI: 10.1016/j.oftale.2025.10.003
C. Martinez-Perez , C. Álvarez-Peregrina , M.Á. Sánchez-Tena , Á. Arance-Gil , C. Villa-Collar
This study explores the interconnections between various publications and authors, identifies distinct research domains concerning light's role in myopia control, and pinpoints the most referenced study within citation networks. A systematic literature search was conducted in the Web of Science database using the keywords “(Myopia OR 'Refractive error') AND (Control OR Treatment OR Therapy OR Management) AND (Light OR Ultraviolet OR Solar OR Outdoors)” covering the period from 1990 to December 2024. Citation Network Explorer, VOSviewer, and CiteSpace were used to analyze the publications. A total of 1,468 publications and 5,473 citation networks were identified, with the highest publication volume in 2023 (153 papers). The most cited article, by He et al. in JAMA 2015, focused on the effect of outdoor time on myopia development among children, receiving 588 citations. The analysis clustered the findings into five key research areas: dopamine's role, outdoor exposure time, red light therapy, scleral cross-linking efficacy, and intrastromal cross-linking benefits. Overall, the citation network provides a comprehensive assessment of significant studies on sunlight and monochromatic light in myopia prevention and management, emphasizing the importance of preventing axial eye growth.
本研究探讨了各种出版物和作者之间的相互联系,确定了关于光在近视控制中的作用的不同研究领域,并在引文网络中确定了被引用最多的研究。使用关键词“(近视或屈光不正)”和“(控制或治疗或治疗或管理)”和“(光或紫外线或太阳能或户外)”在Web of Science数据库中进行系统的文献检索,检索时间为1990年至2024年12月。使用Citation Network Explorer、VOSviewer和CiteSpace对出版物进行分析。共发现1468篇论文和5473个引文网络,其中2023年的论文发表量最高(153篇)。被引用最多的文章是He等人在2015年JAMA上发表的一篇关于户外时间对儿童近视发展的影响的文章,被引用588次。该分析将这些发现集中在五个关键研究领域:多巴胺的作用、户外暴露时间、红光疗法、巩膜交联效果和眼内交联益处。总的来说,引文网络全面评估了日光和单色光在近视预防和管理中的重要研究,强调了防止轴眼生长的重要性。
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引用次数: 0
Acute phase Vogt-Koyanagi-Harada syndrome resistant to corticosteroid therapy in an adult female patient 1例成年女性患者急性期Vogt-Koyanagi-Harada综合征对皮质类固醇治疗的抵抗。
Pub Date : 2025-11-01 DOI: 10.1016/j.oftale.2025.08.003
Z.E. Kurt, M.A. Argin
Vogt-Koyanagi-Harada (VKH) syndrome is a rare inflammatory disease that affects more than one system, including ophthalmological, auditory, cutaneous, and neurological systems. VKH syndrome is mostly characterized by panuveitis with serous retinal detachment, headache, hearing loss, vitiligo, and poliosis. Early diagnosis and proper management are crucial to prevent irreversible visual loss and other complications. We present a case report of VKH syndrome in a 29-year-old female patient. Initiation of corticosteroid therapy led to gradual regression of her symptoms. However, after cessation of corticosteroid therapy, the patient’s visual acuity decreased, and the symptoms reappeared. Consequently, combination therapy with corticosteroid, azathioprine, and cyclosporine controlled the disease and stabilized clinical findings.This article highlights that early diagnosis and treatment of VKH syndrome with corticosteroid along with azathioprine and cyclosporine in the acute phase may improve a patient's quality of life and reduce the severity of the disease.
Vogt-Koyanagi-Harada (VKH)综合征是一种罕见的炎症性疾病,影响多个系统,包括眼科、听觉、皮肤和神经系统。VKH综合征的主要特征是全葡萄膜炎伴浆液性视网膜脱离、头痛、听力丧失、白癜风和脊髓灰质炎。早期诊断和适当治疗对于预防不可逆转的视力丧失和其他并发症至关重要。我们提出一个病例报告的VKH综合征在一个29岁的女性患者。皮质类固醇治疗的开始导致她的症状逐渐消退。然而,停止皮质类固醇治疗后,患者视力下降,症状再次出现。因此,皮质类固醇、硫唑嘌呤和环孢素联合治疗控制了疾病并稳定了临床表现。这篇文章强调早期诊断和治疗VKH综合征在急性期皮质类固醇联合硫唑嘌呤和环孢素可以改善患者的生活质量和降低疾病的严重程度。
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引用次数: 0
Artificial intelligence and telemedicine in oculoplastics: Recent advances, clinical applications, and emerging challenges 人工智能和远程医疗在眼科整形:最新进展,临床应用和新出现的挑战。
Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.018
F. Calleja Casado , A. Caro Ortega , E. Gracia Rovira , A. Duch Samper
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引用次数: 0
Molecular connection between the ocular surface and the inflammasome: New diagnostic and therapeutic perspectives 眼表和炎性体之间的分子连接:新的诊断和治疗观点。
Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.09.001
S. Mora-Sáez , I. Andrés-Blasco , J. Benítez-del-Castillo-Sánchez , V. Zanón-Moreno , C. Peris-Martínez , M.D. Pinazo-Durán
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引用次数: 0
The conceptualization of ‘Key Evidence Leaders’ from ‘Opinion Leaders’: A review also applicable in ophthalmology 从“意见领袖”到“关键证据领袖”的概念:也适用于眼科的综述。
Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.016
J. Fernández , F. Ribeiro , H.B. Dick , T. Kohnen , C. Rocha-de-Lossada , M. Rodríguez-Vallejo
The collaboration of ophthalmologists with the industry, in their role as opinion leaders (OLs) who interpret, modify, and disseminate information to professional networks, is susceptible to bias. This review explores the critical role of OLs in the healthcare industry and their evolution into Key Evidence Leaders (KELs), emphasizing the importance of differentiating KELs from traditional OLs to promote evidence-based practices and maintain research integrity in healthcare. OLs often rely on their reputation and experience, which can make them susceptible to industry biases, particularly when financial incentives are involved. The concept of KELs marks a significant evolution from traditional OLs. Unlike OLs, KELs base their influence on expertise in clinical evidence and research, rather than personal experience or industry affiliations. KELs possess strong analytical skills, engage in interdisciplinary collaboration, and emphasize transparency and unbiased dissemination of information. The emergence of KELs represents a significant shift towards evidence-based leadership in healthcare. Differentiating KELs from traditional OLs is crucial for ensuring that the messages received by healthcare professionals are less biased. By supporting KELs who prioritize patient-centered evidence, the industry can enhance trust in the application of medical devices and drugs.
眼科医生与业界的合作,作为意见领袖(ol)的角色,他们解释、修改并向专业网络传播信息,容易产生偏见。本文探讨了关键证据领导者在医疗保健行业中的关键作用及其向关键证据领导者的演变,强调了将关键证据领导者与传统的关键证据领导者区分开来,以促进循证实践和保持医疗保健研究完整性的重要性。OLs通常依赖于他们的声誉和经验,这可能使他们容易受到行业偏见的影响,特别是在涉及财政激励的情况下。kel的概念标志着传统ol的重大演变。与ol不同,kol的影响力基于临床证据和研究方面的专业知识,而不是个人经验或行业关系。知识分子具有较强的分析能力,从事跨学科合作,并强调透明度和公正的信息传播。KELs的出现代表了医疗保健领域向循证领导的重大转变。区分kell与传统ol对于确保医疗保健专业人员收到的信息较少偏见至关重要。通过支持优先考虑以患者为中心的证据的kel,该行业可以增强对医疗设备和药物应用的信任。
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引用次数: 0
Reconstruction of the upper eyelid after dog bite using a composite graft at pediatric age 小儿犬咬伤后复合移植物重建上眼睑。
Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.015
C.A. Gómez Lanz , B. Palmero Sánchez , M.V. Carmona Pérez , E. Nevado Sánchez
Eyelid lesions in children are always a surgical challenge. We present the case of a 2-year-old girl with subtotal amputation of the upper eyelid due to a dog bite. Immediate surgical reimplantation with a composite graft was performed, achieving complete functional recovery without affecting ocular closure. At 6 years of follow-up, the only sequel was the absence of eyelashes in the affected area. The use of composite grafts seems to be an effective option in this type of injuries, allowing good functional and aesthetic results without limiting future reconstructions.
儿童眼睑病变一直是一个手术挑战。我们提出的情况下,一个2岁的女孩与上眼睑次全截肢,由于狗咬。在不影响闭眼的情况下,立即进行复合移植手术,实现了完全的功能恢复。在6年的随访中,唯一的后遗症是患处没有睫毛。复合移植物的使用似乎是这类损伤的有效选择,可以获得良好的功能和美观效果,而不会限制未来的重建。
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引用次数: 0
Orbital giant primary osteoma: Case report and literature review 眼眶巨大原发性骨瘤1例报告及文献复习。
Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.017
M. Dorronsoro, C. Pagano Boza
Osteoma is a benign, slow-growing bone tumor that primarily affects the jaw and paranasal sinuses. Intraorbital location, whether primary or secondary, is rare. Although it is generally asymptomatic, it can become symptomatic. As it grows, orbital osteoma can cause symptoms due to displacement and compression of the orbital contents posing a risk to vision.
This article is a literature review and case report of a large primary orbital osteoma in a 36-year-old woman, initially asymptomatic and later exhibiting a few symptoms despite significant displacement of the orbital structures that the tumor causes. Its handling was controversial for us because we did not have references on the approach we should be taking. To this date, no cases of asymptomatic intraorbital osteomas of this size have ever been published.
骨瘤是一种生长缓慢的良性骨肿瘤,主要影响下颌和鼻窦。眶内定位,无论是原发性还是继发性,都很少见。虽然它通常是无症状的,但它可以成为症状。随着眼眶骨瘤的生长,眼眶内容物的移位和压迫会引起症状,对视力构成威胁。这篇文章是一篇文献回顾和病例报告,一名36岁的女性,最初无症状,后来表现出一些症状,尽管肿瘤引起的眶结构明显移位。它的处理对我们来说是有争议的,因为我们没有关于我们应该采取的方法的参考资料。到目前为止,没有这种大小的无症状眶内骨瘤的病例被发表过。
{"title":"Orbital giant primary osteoma: Case report and literature review","authors":"M. Dorronsoro,&nbsp;C. Pagano Boza","doi":"10.1016/j.oftale.2025.07.017","DOIUrl":"10.1016/j.oftale.2025.07.017","url":null,"abstract":"<div><div>Osteoma is a benign, slow-growing bone tumor that primarily affects the jaw and paranasal sinuses. Intraorbital location, whether primary or secondary, is rare. Although it is generally asymptomatic, it can become symptomatic. As it grows, orbital osteoma can cause symptoms due to displacement and compression of the orbital contents posing a risk to vision.</div><div>This article is a literature review and case report of a large primary orbital osteoma in a 36-year-old woman, initially asymptomatic and later exhibiting a few symptoms despite significant displacement of the orbital structures that the tumor causes. Its handling was controversial for us because we did not have references on the approach we should be taking. To this date, no cases of asymptomatic intraorbital osteomas of this size have ever been published.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 10","pages":"Pages 644-649"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144777188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automated measurement of ocular movements abnormalities in primary congenital glaucoma using DIVE device: A pilot study of fixation, smooth pursuit and saccadic movements 使用DIVE设备自动测量原发性先天性青光眼的眼球运动异常:固定、平滑追踪和跳眼运动的初步研究。
Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.06.009
L. Morales-Fernandez, C. Heredia-Pastor, P. Talavero, I. Collado, J. Garcia-Feijoo, R. Gomez-de-Liaño

Purpose

Primary congenital glaucoma (PCG) is a significant cause of childhood vision loss. While visual acuity can be measured, it does not always reflect visual functioning in daily life, particularly as oculomotor skills are often compromised in ocular disorders. This pilot study assesses oculomotor behavior in children with PCG compared to healthy peers using the Device for an Integral Visual Examination (DIVE).

Methods

Twelve children with PCG (n = 24 eyes) and 24 healthy children (n = 48 eyes), aged 6 months to 4 years, were recruited. DIVE was used for automated oculomotor assessments, measuring fixation (gaze stability, fixation stability, and duration of fixation), saccadic movements (reaction time, peak velocity), and smooth pursuit (latency, gain).

Results

PCG children showed significantly poorer gaze stability in both short (0.68 log degree2, 0.29–0.94 frente a 0.15 log degree2, −0.17–0.59; p < 0.05) and long tasks (1.08 log degree2, 0.79–1.84 frente a 0.57 log degree2, 0.30–0.85; p < 0.05), and poorer fixation stability in short (−0.20 log degree2, −0.27 to −0.17 frente a −0.48 log degree2, −0.55 to −0.30; p < 0.05) and long tasks (−0.11 log degree2, −0.20 to −0.04 frente a −0.41 log degree2, −0.57 to −0.26; p < 0.05). Fixation durations were shorter, and saccadic reaction times were longer in the PCG group, while pursuit latency showed no significant difference (p = 0.8118).

Conclusions

Children with PCG have significantly impaired oculomotor behavior, including greater instability in gaze and fixation, shorter fixation durations, and longer saccadic reaction times compared to healthy peers.
目的:原发性先天性青光眼(PCG)是儿童视力丧失的重要原因。虽然视力可以测量,但它并不总是反映日常生活中的视觉功能,特别是在眼部疾病中,动眼力往往受到损害。本初步研究使用整体视觉检查设备(DIVE)评估了与健康同龄人相比,患有PCG儿童的动眼肌行为。方法:选取12例PCG患儿(n = 24眼)和24例健康儿童(n = 48眼),年龄6个月~ 4岁。DIVE用于自动眼球运动评估,测量注视(凝视稳定性、注视稳定性和注视持续时间)、扫视运动(反应时间、峰值速度)和平滑追踪(潜伏期、增益)。结果:PCG患儿在短时间内注视稳定性较差(0.68对数度²,0.29-0.94);P 2, 0.79 ~ 1.84, 0.57对数度,0.30 ~ 0.85;p2, -0.20 ~ -0.04, -0.41对数度,-0.57 ~ -0.26;p结论:与健康同龄人相比,患有PCG的儿童眼动行为明显受损,包括凝视和注视更不稳定,注视持续时间更短,跳眼反应时间更长。
{"title":"Automated measurement of ocular movements abnormalities in primary congenital glaucoma using DIVE device: A pilot study of fixation, smooth pursuit and saccadic movements","authors":"L. Morales-Fernandez,&nbsp;C. Heredia-Pastor,&nbsp;P. Talavero,&nbsp;I. Collado,&nbsp;J. Garcia-Feijoo,&nbsp;R. Gomez-de-Liaño","doi":"10.1016/j.oftale.2025.06.009","DOIUrl":"10.1016/j.oftale.2025.06.009","url":null,"abstract":"<div><h3>Purpose</h3><div>Primary congenital glaucoma (PCG) is a significant cause of childhood vision loss. While visual acuity can be measured, it does not always reflect visual functioning in daily life, particularly as oculomotor skills are often compromised in ocular disorders. This pilot study assesses oculomotor behavior in children with PCG compared to healthy peers using the Device for an Integral Visual Examination (DIVE).</div></div><div><h3>Methods</h3><div>Twelve children with PCG (n = 24 eyes) and 24 healthy children (n = 48 eyes), aged 6 months to 4 years, were recruited. DIVE was used for automated oculomotor assessments, measuring fixation (gaze stability, fixation stability, and duration of fixation), saccadic movements (reaction time, peak velocity), and smooth pursuit (latency, gain).</div></div><div><h3>Results</h3><div>PCG children showed significantly poorer gaze stability in both short (0.68 log degree<sup>2</sup>, 0.29–0.94 frente a 0.15 log degree<sup>2</sup>, −0.17–0.59; p &lt; 0.05) and long tasks (1.08 log degree<sup>2</sup>, 0.79–1.84 frente a 0.57 log degree<sup>2</sup>, 0.30–0.85; p &lt; 0.05), and poorer fixation stability in short (−0.20 log degree<sup>2</sup>, −0.27 to −0.17 frente a −0.48 log degree<sup>2</sup>, −0.55 to −0.30; p &lt; 0.05) and long tasks (−0.11 log degree<sup>2</sup>, −0.20 to −0.04 frente a −0.41 log degree<sup>2</sup>, −0.57 to −0.26; p &lt; 0.05). Fixation durations were shorter, and saccadic reaction times were longer in the PCG group, while pursuit latency showed no significant difference (<em>p = 0.8118</em>).</div></div><div><h3>Conclusions</h3><div>Children with PCG have significantly impaired oculomotor behavior, including greater instability in gaze and fixation, shorter fixation durations, and longer saccadic reaction times compared to healthy peers.</div></div>","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 10","pages":"Pages 610-617"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of anterior segment OCT in peripheral ulcerative keratitis 前段OCT在周围性溃疡性角膜炎中的作用。
Pub Date : 2025-10-01 DOI: 10.1016/j.oftale.2025.07.002
C. Parés-Alfonso, D. Oliver-Gutiérrez, E. Ros-Sanchez
{"title":"The role of anterior segment OCT in peripheral ulcerative keratitis","authors":"C. Parés-Alfonso,&nbsp;D. Oliver-Gutiérrez,&nbsp;E. Ros-Sanchez","doi":"10.1016/j.oftale.2025.07.002","DOIUrl":"10.1016/j.oftale.2025.07.002","url":null,"abstract":"","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"100 10","pages":"Pages 652-653"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Archivos de la Sociedad Espanola de Oftalmologia
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