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Acute macular neuroretinopathy associated with migraine. 与偏头痛有关的急性黄斑神经视网膜病变。
Pub Date : 2024-10-31 DOI: 10.1016/j.oftale.2024.10.010
N Domènech-López, V Llorenç, A Moll-Udina, A Adán

Acute macular neuroretinopathy (AMN) is an uncommon entity that affects the outer layer of the retina and usually presents itself as an acute paracentral scotoma. It is mostly seen in young women and the course is usually self-limited. The diagnosis is established by a multimodal image, with optical coherence tomography (OCT) being the preferred technique. The origin is thought to be linked to a possible dysregulation in the flow of the deep vascular plexus of the retina or the choriocapillaris. A clinical case of an AMN in a young woman associated with a migraine attack is presented, highlighting the importance of considering this disease in the differential diagnosis of visual disorders associated with migraines. A physiological and pathological basis between migraine and NMA is suggested.

急性黄斑神经视网膜病变(AMN)是一种不常见的视网膜外层病变,通常表现为急性旁中心性黑矇。它主要见于年轻女性,病程通常是自限性的。诊断需要通过多模态图像来确定,光学相干断层扫描(OCT)是首选技术。其起源被认为与视网膜深层血管丛或绒毛膜的血流可能失调有关。本文介绍了一例年轻女性偏头痛发作时出现视网膜睫状体异常的临床病例,强调了在鉴别诊断与偏头痛有关的视觉障碍时考虑这种疾病的重要性。本文提出了偏头痛与 NMA 之间的生理和病理基础。
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引用次数: 0
Frequency, risk factors and time to resolution of exposure keratopathy in patients in the Pediatric Intensive Care Unit. 儿科重症监护室患者暴露性角膜病的发病率、风险因素和缓解时间。
Pub Date : 2024-10-31 DOI: 10.1016/j.oftale.2024.10.011
R A Pech-Lugo, A Vázquez-Cerón, F K Segura López, A Dávila-Camargo

Background and objective: Exposure keratopathy (EPK) is characterized by punctate erosions of the corneal epithelium, mainly located in the lower third of the cornea. In the Pediatric Intensive Care Unit (PICU), an incidence of 19-25 % has been reported. The objective of this study was to describe the frequency, risk factors, and time to resolution of exposure keratitis in PICU patients.

Materials and methods: Descriptive, observational, longitudinal, prospective study. The association of keratitis due to exposure to risk factors was evaluated using the Chi square test and determining the OR and 95% confidence interval.

Results: 81 patients admitted to the PICU between March and September 2023 were included, 46 (56.79%) developed PEK, 67.39% (31/46) grade 1 and 26.08% (12/46) grade 3. The median time Resolution was 3 days, interquartile range (2-5). A significant difference was observed between patients with and without PEK in the requirement for mechanical ventilation 86.13% vs., 54.29% p = 0.01, OR = 6.905 (2.20-21.64), sedation 100% vs., 85.71%, p = 0.02, in the duration of sedation 5 days vs. 2.5 days (p = 0.024), neuromuscular relaxation 21.74% vs., 0%, p = 0.002, Lagoftalmos 86.94% vs., 31.43% p < 0.00001, OR = 13.33 (4.42-40.17), chemosis 15.21% vs., 0%, p = 0.014 and days of stay in the PICU median 7 (5-11) vs. 3 (2-6), p < 0.00001.

Conclusions: The frequency of QPE observed was 56.79%, higher than that previously reported in the literature in the pediatric population. Mechanical ventilation, sedation, duration of sedation, Lagoftalmos chemosis and days of stay in the PICU were identified as risk factors.

背景和目的:暴露性角膜病(EPK)的特征是角膜上皮点状糜烂,主要位于角膜的下三分之一处。据报道,在儿科重症监护病房(PICU)中,其发病率为 19%-25%。本研究旨在描述儿科重症监护室患者暴露性角膜炎的发病频率、风险因素和缓解时间:描述性、观察性、纵向、前瞻性研究。研究结果:81 名 PICU 患者的暴露性角膜炎发生率与风险因素的相关性用智平方检验进行了评估,并确定了 OR 和 95% 的置信区间:研究纳入了 2023 年 3 月至 9 月期间入住 PICU 的 81 名患者,其中 46 人(56.79%)患 PEK,67.39%(31/46)为 1 级,26.08%(12/46)为 3 级。解救时间中位数为 3 天,四分位数间距(2-5)。在机械通气需求方面,86.13% 的患者与 54.29% 的患者之间存在明显差异,P = 0.01,OR = 6.905(2.20-21.64),镇静 100% 的患者与 85.71% 的患者之间存在明显差异,P = 0.02,镇静持续时间 5 天与 2.5 天之间存在明显差异(P = 0.024),神经肌肉松弛 21.74% 的患者与 0% 的患者之间存在明显差异,P = 0.002,Lagoftalmos 86.94% 的患者与 31.43% 的患者之间存在明显差异:观察到的 QPE 发生率为 56.79%,高于之前文献报道的儿科人群的发生率。机械通气、镇静、镇静持续时间、Lagoftalmos 化疗和在重症监护病房的住院天数被确定为风险因素。
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引用次数: 0
Role of vitrectomy for syphilitic uveitis in a tertiary hospital in Spain 西班牙一家三级医院玻璃体切除术在梅毒葡萄膜炎治疗中的作用。
Pub Date : 2024-10-01 DOI: 10.1016/j.oftale.2024.05.010
Diagnosis and treatment of ocular syphilis can be challenging due to the wide spectrum of clinical presentations of this sexually transmitted disease. In some cases of syphilitic panuveitis, pars plana vitrectomy (PPV) can be useful in management since it plays an important role in improving fundus examination allowing treatment of possible retinal associated lesions when vitreous inflammation is intense. We present 3 cases of patients with ocular syphilis that underwent a therapeutic PPV, vitreous sample was taken and analyzed in two of them.
由于这种性传播疾病的临床表现多种多样,因此眼梅毒的诊断和治疗具有挑战性。在某些梅毒性泛葡萄膜炎病例中,玻璃体旁切除术(PPV)在治疗中非常有用,因为它在改善眼底检查方面发挥着重要作用,当玻璃体炎症严重时,可以治疗可能的视网膜相关病变。我们介绍了3例接受治疗性玻璃体切割术的眼梅毒患者,其中两例患者的玻璃体样本已采集并进行了分析。
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引用次数: 0
Non-arteritic anterior ischemic optic neuropathy as the only manifestation of a malignant hypertensive crisis: Report of a case 非动脉炎性前部缺血性视神经病变是恶性高血压危象的唯一表现:病例报告。
Pub Date : 2024-10-01 DOI: 10.1016/j.oftale.2024.06.007
Non-arteritic anterior ischemic optic neuropathy (NAION) is after glaucoma the most common optic neuropathy in patients over 50 years. It is known that high blood pressure (HBP) is an important risk factor for the development of NAION. It is also known that malignant arterial hypertension (MAH) could be accompanied by optic disc edema. However, MAH has not classically been considered a cause of NAION. We report the case of a 32-year-old patient who presented irreversible visual loss with a pattern compatible with NAION as the only manifestation of a hypertensive crisis.
非动脉炎性前部缺血性视神经病变(NAION)是继青光眼之后,50 岁以上患者最常见的视神经病变。众所周知,高血压(HBP)是诱发非动脉炎性前部缺血性视神经病变的重要危险因素。人们还知道,恶性动脉高血压(MAH)可能伴有视盘水肿。然而,恶性动脉高血压并不被认为是NAION的病因。我们报告了一例 32 岁患者的病例,该患者出现了不可逆转的视力下降,其模式与 NAION 相符,是高血压危象的唯一表现。
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引用次数: 0
Fibrinous bullous central serous chorioretinopathy with exudative retinal detachment 纤维素性大疱性中心性浆液性脉络膜视网膜病变伴渗出性视网膜脱离。
Pub Date : 2024-10-01 DOI: 10.1016/j.oftale.2024.07.003
K. Arun, B. Demir, A. Makuloluwa
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引用次数: 0
Effectiveness of pars plana Ahmed® valve implantation in patients with refractory glaucoma 在难治性青光眼患者中实施 Ahmed® 瓣膜植入术的效果。
Pub Date : 2024-10-01 DOI: 10.1016/j.oftale.2024.07.009
O.L. Teherán Forero , J.V. Rios Moreno , M. Ochoa-Díaz , E. Ramos-Clason

Purpose

To evaluate the success rate and complications of the Ahmed FP7 valve implanted via Pars Plana in a group of vitrectomized patients with refractory glaucoma and anterior segment abnormalities from January 2018 to June 2023.

Methods

Quasi-experimental, prospective study. Eleven eyes with refractory glaucoma were included. Participants underwent a comprehensive ophthalmic examination, including assessment of intraocular pressure (IOP) reduction, visual acuity, characterization of glaucoma type, and number of antiglaucoma medications.

Results

The mean baseline IOP was 37.3 ± 11 mmHg, which decreased to 13.5 ± 3.0 mmHg after one year. The qualified success rate was 63.7%, while the complete success rate was 36.3%. The most common diagnosis was neovascular glaucoma in 36.4% of cases. The most frequent postoperative complications were choroidal detachment and hypotony.

Conclusions

Our data suggest that implantation of the Ahmed FP7 valve via pars plana is an effective and safe option for patients with refractory secondary glaucoma.
目的:评估 2018 年 1 月至 2023 年 6 月期间,在一组经玻璃体切除术治疗的难治性青光眼和眼前节异常患者中,经旁路植入 Ahmed FP7 瓣膜的成功率和并发症:准实验前瞻性研究。共纳入 11 名患有难治性青光眼的患者。参与者接受了全面的眼科检查,包括评估眼压降低情况、视力、青光眼类型特征以及抗青光眼药物的数量:平均基线眼压为 37.3 ± 11 mmHg,一年后降至 13.5 ± 3.0 mmHg。合格成功率为 63.7%,完全成功率为 36.3%。最常见的诊断是新生血管性青光眼,占 36.4%。最常见的术后并发症是脉络膜脱离和眼压过低:我们的数据表明,对于难治性继发性青光眼患者来说,通过眼旁植入 Ahmed FP7 瓣膜是一种有效而安全的选择。
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引用次数: 0
Case report: A rare case of cyclodialysis after cataract surgery managed exclusively with medical therapy 病例报告:一例罕见的白内障术后循环透析病例,完全采用药物治疗。
Pub Date : 2024-10-01 DOI: 10.1016/j.oftale.2024.05.008
We present the case of a 68-year-old female who presented with a substantial cyclodialysis after phacoemulsification identified by anterior segment optical coherence tomography and ultrasound biomicroscopy. Gonioscopy is challenging because of its shallow anterior chamber. Due to lack of response to topical steroids and refusal by the patient for surgical treatment, topical steroids were tapered, and cycloplegic was initiated. After two weeks, the cyclodialysis cleft was closed on optical coherence tomography persisting residual subchoroidal fluid, topical treatment was mantained. Despite of this, visual acuity and hypotony were restored. Finally at 2 months visit subchoroidal fluid was reabsorbed and patient was discharged.
Clinics should consider the possibility of cyclodialysis in cases of unjustified hypotony during postoperative period. In addition, we recommend performing anterior segment imaging which includes ultrasound biomicroscopy and optical coherence tomography, when the evaluation of angular structures is unfeasible. Finally, we propose medical management for severe cyclodialysis as the first option considering anti-inflammatory drugs could perpetrate the separation between scleral spur and ciliary muscle.
我们介绍了一例 68 岁女性的病例,她在接受超声乳化术后出现了大量的环状渗出,经前节光学相干断层扫描和超声生物显微镜检查发现了这一情况。由于前房较浅,巩膜镜检查具有挑战性。由于对局部类固醇缺乏反应,患者又拒绝手术治疗,因此局部类固醇逐渐减少,并开始使用环磷酰胺。两周后,光学相干断层扫描显示环形透析裂隙闭合,但仍有残留的脉络膜下积液,局部治疗仍在继续。尽管如此,患者的视力和眼底仍得到了恢复。最后,在 2 个月的回访中,脉络膜下积液被重新吸收,患者康复出院。对于术后出现不合理低视力的病例,诊所应考虑循环透析的可能性。此外,如果无法评估角膜结构,我们建议进行眼前节成像,包括超声生物显微镜和光学相干断层扫描。最后,考虑到抗炎药物可能会导致巩膜骨刺和睫状肌之间的分离,我们建议首选药物治疗严重的环状渗出。
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引用次数: 0
Orbital trochleitis: Literature review 眼眶套管炎:文献综述。
Pub Date : 2024-10-01 DOI: 10.1016/j.oftale.2024.06.008
Trochleitis is clinically and/or radiologically evidenced inflammation of the trochlea or orbital pulley.
Clinically it is characterized by pain and hypersensitivity in the superomedial orbital angle, which is increased or triggered by direct palpation of the area and/or eye movements. During the REM (rapid eye movements) phase of sleep, patients with trochleitis suffer from nocturnal micro-awakenings that impede their rest, and pain is often associated with visual symptoms (diplopia or Brown's syndrome).
The lack of common guidelines for diagnosis and treatment of this disease, its low prevalence and the lack of knowledge of the different entities associated with trochlear pain, leads to underdiagnosis or misdiagnosis. It is essential to know the characteristics of this pathology and to diagnose it correctly, differentiating it from other trochlear pain entities, in order to be able to carry out an adequate therapeutic and prognostic approach. The lack of consensus on the therapeutic protocol means that various treatments are used, in different order and often with a combination of several without a firm scientific basis.
This comprehensive review of previous studies concludes that nonsteroidal anti-inflammatory drugs (NSAIDs) achieve an overall complete cure rate of 77%, although this rate decreases to 30% in case of motility restriction or diplopia. Intratrochlear corticosteroid injection achieves an overall complete cure rate of 86%, even in the worst prognosis trochleitis, being the only effective option in NSAID-refractory trochleitis and currently being questioned as the first treatment option.
蝶窦炎是指蝶窦或眶轮在临床和/或放射学上表现出的炎症。临床表现为眶上内角疼痛和过敏,直接触诊该区域和/或眼球运动时疼痛加剧或触发。在快速眼动(REM)睡眠阶段,套管炎患者会出现夜间微觉醒,妨碍其休息,疼痛往往与视觉症状(复视或布朗综合征)有关。由于缺乏诊断和治疗这种疾病的通用指南、发病率低以及对与套管痛相关的不同实体缺乏了解,导致诊断不足或误诊。必须了解这种病症的特征,并正确诊断,将其与其他蹄叶疼痛实体区分开来,这样才能采取适当的治疗和预后方法。由于对治疗方案缺乏共识,因此在没有可靠科学依据的情况下,人们采用了各种不同顺序的治疗方法,而且往往是几种方法的组合。对以往研究的全面回顾得出结论,非甾体类抗炎药(NSAIDs)的总体完全治愈率为 77%,但在运动受限或复视的情况下,治愈率降至 30%。即使是预后最差的套管炎,蜗管内注射皮质类固醇的总体完全治愈率也达到了86%,是非甾体抗炎药难治性套管炎的唯一有效选择,目前作为第一治疗选择受到质疑。
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引用次数: 0
Perception of patients with retinal pathology on aspects of visual function and their management 视网膜病变患者对视觉功能及其管理方面的看法。
Pub Date : 2024-10-01 DOI: 10.1016/j.oftale.2024.06.011

Background and objective

Age-related macular degeneration (AMD) and diabetic retinopathy (DR) are highly prevalent.

Objective

To explore perceptions of patients with AMD or DR about the impact of the disease and treatment on their daily living activities.

Materials and methods

Semi-structured interviews with a questionnaire developed from validated patient reported outcomes questionnaires. The questionnaire consisted of 19 questions about the disease and 9 about the treatment. The questions (items) were answered on a scale from 1 to 9. In addition, the patient interviewed was invited to make free comments on each question. Nine patients with AMD and 9 with DR were interviewed by videoconference or telephone call. A quantitative analysis of the responses and a qualitative analysis of the comments were carried out.

Results

The most relevant item for patients with AMD or DR is “Recognize people when they are nearby”, and “Read text in normal size font in a newspaper or book”, followed, in patients with AMD, by “Do things what you would like” and, in patients with DR, “Feeling frustrated by the vision problems.” Regarding the treatment, the most relevant aspects for both groups is that the treatment works and receiving appropriate information before and after the treatment. The qualitative comments were focused to the disease, the treatment, and to the role of doctors and the health system.

Conclusion

Quantitative responses and free comments can be useful to improve the care of patients with AMD or DR by physicians and the health system.
背景和目的:老年性黄斑变性(AMD)和糖尿病视网膜病变(DR)的发病率很高:探讨老年性黄斑变性或糖尿病视网膜病变患者对疾病和治疗对其日常生活活动的影响的看法:半结构式访谈,问卷由经过验证的患者报告结果问卷编制而成。问卷包括 19 个关于疾病的问题和 9 个关于治疗的问题。这些问题(项目)按 1 到 9 的评分标准进行回答。此外,受访患者还可就每个问题自由发表意见。9 名 AMD 患者和 9 名 DR 患者通过视频会议或电话接受了访谈。对回答进行了定量分析,对评论进行了定性分析:与 AMD 或 DR 患者最相关的项目是 "认出附近的人 "和 "阅读报纸或书籍中正常大小字体的文字",其次是 AMD 患者的 "做自己想做的事 "和 DR 患者的 "因视力问题而感到沮丧"。关于治疗,两组患者最关心的问题都是治疗是否有效,以及在治疗前后是否获得了适当的信息。定性评论的重点是疾病、治疗以及医生和医疗系统的作用:定量回答和自由评论有助于改善医生和医疗系统对老年性视网膜病变(AMD)或动力障碍性视网膜病变(DR)患者的护理。
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引用次数: 0
PHOMS: An apt and accurate acronym PHOMS:一个恰当而准确的缩写。
Pub Date : 2024-10-01 DOI: 10.1016/j.oftale.2024.06.012
{"title":"PHOMS: An apt and accurate acronym","authors":"","doi":"10.1016/j.oftale.2024.06.012","DOIUrl":"10.1016/j.oftale.2024.06.012","url":null,"abstract":"","PeriodicalId":93886,"journal":{"name":"Archivos de la Sociedad Espanola de Oftalmologia","volume":"99 10","pages":"Pages 464-466"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141443922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Archivos de la Sociedad Espanola de Oftalmologia
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