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The textbook outcome for cholecystectomy: Is it a good quality tool for a low-morbidity procedure? 胆囊切除术的教科书结果:对于低发病率手术而言,它是一个优质工具吗?
Pub Date : 2024-06-20 DOI: 10.1016/j.cireng.2024.06.004
David Hernández-Bermejo, Celia García-Vega, Juan Jesús Rubio-García, Celia Villodre-Tudela, Silvia Carbonell-Morote, José Manuel Ramia

Introduction: Cholelithiasis is the most common hospital diagnosis of the digestive system, and its treatment, if symptomatic, is laparoscopic cholecystectomy. There is a growing need for comprehensive determination of postoperative outcomes and the efficiency of healthcare facilities. The "textbook outcome"(TO) indicates the quality of care commonly used in oncological procedures, obtained by adding several postoperative parameters, which informs whether a perfect result has been obtained. The main objective of this study is to determine the TO for cholecystectomy and to see the factors that influence its achievement.

Methods: Retrospective observational unicentric cohort study on patients who underwent cholecystectomy between 2018-2020. We defined TO as those patients who met the following premises: Clavien-Dindo complications < III, postsurgical stay less than the 75th percentile (<3 days), and no readmissions or mortality in the first ninety days. Perioperative characteristics were analyzed, and the patients were divided into two groups according to whether or not they achieved TO. We defined criteria for difficult cholecystectomy according to the operative report.

Results: The percentage of TO was 72% (342/475) (82.6% in elective surgery and 60.5% in urgent surgery). The univariate analysis showed that the following factors are associated with achieving TO: female sex, age <63 years, ASA risk < III, elective surgery, laparoscopic approach, and not difficult cholecystectomy. After multivariate analysis ASA < III (OR 2.39 CI95% 1.37-4.16), elective surgery (OR 2.77 CI95% 1.64-4.67), laparoscopic approach (OR 5.71 CI95% 2.89-11.30) and not to be difficult cholecystectomy (OR 0.42 CI95% 0.259-0.71) remained statistically significant.

Conclusions: The TO is a healthcare quality tool that is simple to perform, easily interpretable, and helpful for evaluating quality in healthcare and comparing centers. It applies not only to oncological procedures but also to cholecystectomy.

导言:胆石症是消化系统最常见的医院诊断,如果有症状,其治疗方法是腹腔镜胆囊切除术。对术后疗效和医疗机构效率的综合判定需求日益增长。教科书式疗效"(TO)指的是肿瘤手术中常用的护理质量,它是通过添加多个术后参数而获得的,可告知是否获得了完美的疗效。本研究的主要目的是确定胆囊切除术的 "教科书结果",并了解影响其实现的因素:对 2018-2020 年间接受胆囊切除术的患者进行回顾性观察单中心队列研究。我们将 TO 定义为满足以下前提条件的患者:Clavien-Dindo并发症 结果:TO的比例为72%(342/475)(82.6%为择期手术,60.5%为紧急手术)。单变量分析表明,以下因素与实现 TO 有关:女性性别、年龄 结论:TO 是一种医疗质量工具,操作简单,易于解释,有助于评估医疗质量和比较医疗中心。它不仅适用于肿瘤手术,也适用于胆囊切除术。
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引用次数: 0
Results of the implementation of a specialized cervical tracheal surgery program. 实施专门的颈部气管手术计划的结果。
Pub Date : 2024-06-20 DOI: 10.1016/j.cireng.2024.05.014
Usue Caballero-Silva, Sara Fra-Fernández, C Ristina Cavestany García-Matres, Albarto Cabañero-Sánchez, Nicolás Moreno-Mata
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引用次数: 0
Impact of the laparoscopic approach, early closure and preoperative stimulation on outcomes of ileostomy closure after rectal resection. 腹腔镜方法、早期闭合和术前刺激对直肠切除术后回肠造口闭合效果的影响。
Pub Date : 2024-06-20 DOI: 10.1016/j.cireng.2024.05.013
Andrea Norte, Carmen Martínez, Ana Pasalodos, Ivette Tort, Anna Sánchez, Pilar Hernández, Jesús Bollo, Eduard Maria Targarona

Aim: To evaluate the clinical outcome of early closure of a protective ileostomy and preoperative stimulation of the efferent limb in a cohort of patients with rectal cancer treated surgically, primarily using the laparoscopic approach.

Methods: We performed an observational retrospective cohort study in a prospectively recorded series of patients with rectal cancer who underwent laparoscopic surgery with a protective loop ileostomy between 2017 and 2022. Ileostomy closure was programmed for within 3 months after surgery. All patients underwent stimulation of the efferent limb. Primary outcomes were morbidity and mortality, length of stay (LOS), and re-admission.

Results: Between 2017 and 2022, 108 patients underwent resection for rectal cancer and protective ileostomy. The laparoscopic approach was performed in 84.3% of patients (n = 91). Permanent ileostomy was performed in 5 patients (4.6%). Ileostomy closure was thus performed in 95.4% of patients (n = 103). Median time to closure was 74.5 days (range 57-113). In 63.1% (n = 65) of patients, reconstructive surgery was performed within 90 days. Prior to closure, efferent limb stimulation was performed in 77.8% (n = 84) of patients. Global morbidity was 26.2% (n = 27) (85.19%, n = 23 Clavien-Dindo I and 7.41%, n = 2 Clavien-Dindo II). The main causes of morbidity were postoperative ileus (10.7%, n = 11) and rectal bleeding (8.7%, n = 9). Anastomosis leakage occurred in 2 patients. Median hospital stay was 6 days (5-7). Readmission was needed in 6.8% (n = 7) of patients.

Conclusion: A previous laparoscopic approach, early closure and stimulation of the efferent limb could be a useful strategy to reduce the morbidity and mortality of temporary ileostomy closure.

目的:评估在一组主要采用腹腔镜方法进行手术治疗的直肠癌患者中,早期关闭保护性回肠造口并在术前刺激传出肢体的临床效果:我们对 2017 年至 2022 年期间接受腹腔镜手术并行保护性环形回肠造口术的一系列直肠癌患者进行了一项前瞻性记录的观察性回顾性队列研究。回肠造口关闭计划在术后 3 个月内完成。所有患者都接受了传出肢体刺激。主要结果为发病率和死亡率、住院时间(LOS)和再次入院:2017年至2022年间,108名患者接受了直肠癌切除术和保护性回肠造口术。84.3%的患者(n = 91)接受了腹腔镜手术。5名患者(4.6%)接受了永久性回肠造口术。因此,95.4% 的患者(103 人)进行了回肠造口关闭术。中位关闭时间为 74.5 天(57-113 天不等)。63.1%的患者(n = 65)在 90 天内进行了重建手术。77.8%的患者(n = 84)在闭合前接受了传出肢体刺激。总发病率为 26.2%(n = 27)(85.19%,n = 23 例 Clavien-Dindo I 型和 7.41%,n = 2 例 Clavien-Dindo II 型)。发病的主要原因是术后回肠梗阻(10.7%,n = 11)和直肠出血(8.7%,n = 9)。2名患者出现吻合口漏。住院时间中位数为 6 天(5-7 天)。6.8%(7 例)的患者需要再次入院:结论:前腹腔镜方法、早期闭合和刺激传出肢体是降低临时回肠造口闭合术发病率和死亡率的有效策略。
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引用次数: 0
Impact of indocyanine green angiography on anastomotic dehiscence rate in colorectal surgery: a systematic review and meta-analysis of randomized studies. 吲哚菁绿血管造影对结直肠手术吻合口开裂率的影响:随机研究的系统回顾和荟萃分析。
Pub Date : 2024-06-06 DOI: 10.1016/j.cireng.2024.06.002
Zutoia Balciscueta Coltell, Izaskun Balciscueta Coltell, Natalia Uribe Quintana

Final del formulario Anastomotic dehiscence, a feared complication in colorectal surgery, motivates the search for effective strategies to mitigate its risk. This meta-analysis encompasses all published randomized trials investigating and comparing the impact of indocyanine green (ICG) angiography on this complication. With four studies and 1,109 patients, the intraoperative ICG angiography group demonstrated a significant reduction in the overall rate of anastomotic dehiscence compared to the non-angiography group (7.3% vs. 11.5%; OR: 0.6; 95% CI: 0.4-0.9; p = 0.03). These differences were maintained in rectal surgery subgroup, with no prolongation of surgical time or increase in morbidity and mortality. There were no differences in the left colon surgery group. The evidence provided by this meta-analysis would support the effectiveness of ICG angiography in reducing the incidence of anastomotic leakage in colorectal surgery, advocating for its integration into routine surgical practice.

最终版本 吻合口裂开是结直肠手术中一种可怕的并发症,促使人们寻找有效的策略来降低其风险。这项荟萃分析涵盖了所有已发表的随机试验,这些试验调查并比较了吲哚青绿(ICG)血管造影术对这种并发症的影响。在四项研究和 1,109 名患者中,术中 ICG 血管造影组比非血管造影组显著降低了吻合口开裂的总发生率(7.3% 对 11.5%;OR:0.6;95% CI:0.4-0.9;P = 0.03)。这些差异在直肠手术亚组中保持不变,手术时间没有延长,发病率和死亡率也没有增加。左结肠手术组没有差异。该荟萃分析提供的证据支持 ICG 血管造影在降低结直肠手术吻合口漏发生率方面的有效性,主张将其纳入常规手术实践中。
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引用次数: 0
Abdominal adhesion causing obstruction and necrosis of the gallbladder's fundus. 腹腔粘连导致胆囊底梗阻和坏死。
Pub Date : 2024-06-03 DOI: 10.1016/j.cireng.2024.05.005
Benjamin Thorpe Plaza, Manuel Paz, Manuel Bustamante Montalvo
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引用次数: 0
Systematic review and meta-analysis as tools for evidence-based medicine 系统综述和荟萃分析是循证医学的工具。
Pub Date : 2024-06-01 DOI: 10.1016/j.cireng.2024.04.006
Marina Iniesta-Sepúlveda , Antonio Ríos
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引用次数: 0
Laparoscopic trans-abdominal repair for a second recurrence of umbilical hernia 腹腔镜经腹修补术治疗二次复发的脐疝。
Pub Date : 2024-06-01 DOI: 10.1016/j.cireng.2024.03.001
Génesis Parra-Eslava, Carlos Vaqué-Alcázar, Elena Martıínez-Guerrero, Jetzabel Soria-Estrems
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引用次数: 0
Sheathed goring: an unusual bull-horn injury 鞘状穿刺:一种不寻常的牛角伤。
Pub Date : 2024-06-01 DOI: 10.1016/j.cireng.2023.10.011
Ana Benítez Riesco, María del Carmen Fernández Moreno, Claudia Gil Alfosea, David Casado Rodrigo
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引用次数: 0
Comparison of abdominal adipose tissue versus body mass index (BMI) as a predictor of complications and survival in liver transplantation 腹部脂肪组织与体重指数(BMI)作为肝移植并发症和存活率预测指标的比较。
Pub Date : 2024-06-01 DOI: 10.1016/j.cireng.2024.02.010
Enrique Toledo , Gema Canal , Sara Sánchez , Juan Echeverri , Roberto Fernández , Mª del Mar Achalandabaso , Edward J. Anderson , Federico Castillo , Juan Carlos Rodríguez

Introduction

Because of the obesity epidemic, more obese patients are on liver transplant (LT) waiting lists. The diseases associated with obesity may increase complications and limit survival after LT. However, there is no established measure or cut-off point to determine this impact and aid decision making. The aim of the present study is to evaluate obesity in patients undergoing LT via BMI and CT-based measurement of adipose tissue (AAT). These parameters will be used to predict the risk of postoperative complications and 5-year survival.

Methods

A retrospective, single-center study was carried out at a tertiary Spanish hospital, including all patients who received LT between January 2012 and July 2019 (n = 164).

The patients were adults who underwent LT using the ‘piggyback’ technique, preserving the recipient vena cava. Visceral adipose tissue (VAT) and BMI were calculated to examine correlations with postoperative complications and 5-year survival.

Results

No significant association was found between postoperative complications by Comprehensive Complication Index, BMI, AAT/height, subcutaneous fat/height and VAT/height.

Kaplan-Meier curves for 5-year survival compared LT recipients with BMI < 30.45 versus ≥30.45, with an estimated survival of 58.97 months versus 43.11 months, respectively (P < .001) (Fig. 3) and for LT recipients with an AAT/height <27.35 mm versus ≥27.35 mm, with an estimated survival of 57.69 months versus 46.34 months (P = .001).

Conclusions

This study does not show a higher rate of postoperative complications in obese patients. There is a significantly lower long-term survival in patients with AAT/height ≥27.35 mm and BMI ≥ 30.45. BMI is a valid estimate of obesity and is predictive of survival.

导言:由于肥胖症的流行,越来越多的肥胖患者被列入肝移植(LT)候选名单。与肥胖相关的疾病可能会增加并发症,限制肝移植后的存活率。然而,目前还没有既定的衡量标准或临界点来确定这种影响并帮助做出决策。本研究旨在通过体重指数(BMI)和基于 CT 的脂肪组织(AAT)测量来评估接受 LT 患者的肥胖情况。这些参数将用于预测术后并发症风险和 5 年生存率:西班牙一家三级甲等医院开展了一项回顾性单中心研究,研究对象包括2012年1月至2019年7月期间接受LT手术的所有患者(n = 164)。患者均为成人,采用 "捎带 "技术接受了LT手术,保留了受体腔静脉。计算了内脏脂肪组织(VAT)和体重指数,以研究与术后并发症和5年生存率的相关性:结果:根据综合并发症指数、体重指数、内脏脂肪组织/身高、皮下脂肪/身高和内脏脂肪组织/身高计算的术后并发症之间无明显关联。与 BMI 的 LT 受者相比,5 年生存率的 Kaplan-Meier 曲线 结论:该研究并未显示出更高的术后并发症发生率:本研究并未显示肥胖患者的术后并发症发生率更高。AAT/身高≥27.35毫米和BMI≥30.45的患者长期生存率明显较低。体重指数是对肥胖的有效估计,并可预测生存率。
{"title":"Comparison of abdominal adipose tissue versus body mass index (BMI) as a predictor of complications and survival in liver transplantation","authors":"Enrique Toledo ,&nbsp;Gema Canal ,&nbsp;Sara Sánchez ,&nbsp;Juan Echeverri ,&nbsp;Roberto Fernández ,&nbsp;Mª del Mar Achalandabaso ,&nbsp;Edward J. Anderson ,&nbsp;Federico Castillo ,&nbsp;Juan Carlos Rodríguez","doi":"10.1016/j.cireng.2024.02.010","DOIUrl":"10.1016/j.cireng.2024.02.010","url":null,"abstract":"<div><h3>Introduction</h3><p>Because of the obesity epidemic, more obese patients are on liver transplant (LT) waiting lists. The diseases associated with obesity may increase complications and limit survival after LT. However, there is no established measure or cut-off point to determine this impact and aid decision making. The aim of the present study is to evaluate obesity in patients undergoing LT via BMI and CT-based measurement of adipose tissue (AAT). These parameters will be used to predict the risk of postoperative complications and 5-year survival.</p></div><div><h3>Methods</h3><p>A retrospective, single-center study was carried out at a tertiary Spanish hospital, including all patients who received LT between January 2012 and July 2019 (n = 164).</p><p>The patients were adults who underwent LT using the ‘piggyback’ technique, preserving the recipient vena cava. Visceral adipose tissue (VAT) and BMI were calculated to examine correlations with postoperative complications and 5-year survival.</p></div><div><h3>Results</h3><p>No significant association was found between postoperative complications by Comprehensive Complication Index, BMI, AAT/height, subcutaneous fat/height and VAT/height.</p><p>Kaplan-Meier curves for 5-year survival compared LT recipients with BMI &lt; 30.45 versus ≥30.45, with an estimated survival of 58.97 months versus 43.11 months, respectively (<em>P</em> &lt; .001) (Fig. 3) and for LT recipients with an AAT/height &lt;27.35 mm versus ≥27.35 mm, with an estimated survival of 57.69 months versus 46.34 months (<em>P</em> = .001).</p></div><div><h3>Conclusions</h3><p>This study does not show a higher rate of postoperative complications in obese patients. There is a significantly lower long-term survival in patients with AAT/height ≥27.35 mm and BMI ≥ 30.45. BMI is a valid estimate of obesity and is predictive of survival.</p></div>","PeriodicalId":93935,"journal":{"name":"Cirugia espanola","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140178258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Usefulness of extended inflammatory parameters related to neutrophil activation reported by Sysmex XN-1000 hematology analyzer for predicting complicated acute appendicitis. Comparison with canonical inflammatory laboratory tests Sysmex XN-1000 血液分析仪报告的与中性粒细胞活化有关的扩展炎症参数对预测复杂性急性阑尾炎的有用性。与典型炎症实验室测试的比较。
Pub Date : 2024-06-01 DOI: 10.1016/j.cireng.2023.11.022
María Isabel Díaz López , Elena Crespo Álvarez , Álvaro Martínez Manzano , Eloísa Urrechaga , Manuel Tomás Orgaz Morales , Mercedes González Morales , Elena Martín García , Luis García de Guadiana-Romualdo

Aim

Accurate diagnosis of complicated appendicitis is of importance to ensure that patients receive early and effective treatment, minimizing the risk of postoperative complications to promote successful recovery. Biochemical markers are a promising tool to identify complicated appendicitis. We aimed to evaluate the potential role of novel parameters related with neutrophil activation, known as “Extended Inflammation Parameters” (EIP), included in blood cell count reported by Sysmex XN-Series analyzers, compared to other canonical biomarkers in identifying complicated appendicitis.

Method

Prospective observational study including patients with confirmed diagnosis of acute appendicitis. C-reactive protein (CRP), procalcitonin, cell blood count, including white blood cell (WBC), absolute neutrophil (ANC) and immature granulocyte (IG) count and EIP (neutrophil reactivity [NEUT-RI] and granularity intensity [NEUT-GI]) were analyzed before surgery. Their accuracy to diagnose complicated appendicitis was tested in an ROC curve analysis.

Results

Our population study included 119 patients, and appendicitis was complicated in 58 (48.7%). NLR, CRP and procalcitonin levels, ANC and IG count and NEUT-RI and NEUT-GI were higher in patients with complicated appendicitis. Regarding accuracy for complicated appendicitis, CRP was the biomarker with the highest performance (ROC AUC: 0.829), with an optimal cutoff of 73.1 mg/L (sensitivity: 63.8%, specificity: 88.5%). NEUT-RI and NEUT-GI achieved both significant but poor accuracy, with ROC AUC of 0.606 and 0.637, respectively.

Conclusions

Novel laboratory tests reported by Sysmex XN-Series analyzers have poor accuracy for identifying complicated appendicitis. In this study, CRP was the biomarker with the highest performance and may be useful as predictor of the severity of acute appendicitis.

目的:准确诊断复杂性阑尾炎非常重要,可确保患者及早接受有效治疗,最大限度地降低术后并发症的风险,促进患者顺利康复。生化指标是鉴别复杂性阑尾炎的有效工具。我们的目的是评估 Sysmex XN 系列分析仪报告的血细胞计数中包含的与中性粒细胞活化有关的新参数(称为 "扩展炎症参数"(EIP))与其他典型生物标志物相比在鉴别复杂性阑尾炎方面的潜在作用:前瞻性观察研究,包括确诊为急性阑尾炎的患者。手术前对 C 反应蛋白(CRP)、降钙素原、细胞计数(包括白细胞、绝对中性粒细胞和未成熟粒细胞计数)和 EIP(中性粒细胞反应性 [NEUT-RI] 和粒度强度 [NEUT-GI])进行分析。通过 ROC 曲线分析检验了它们诊断复杂性阑尾炎的准确性:我们的研究共纳入 119 例患者,其中 58 例(48.7%)为复杂性阑尾炎。复杂性阑尾炎患者的 NLR、CRP 和降钙素原水平、ANC 和 IG 计数以及 NEUT-RI 和 NEUT-GI 均较高。就复杂性阑尾炎的准确性而言,CRP 是性能最高的生物标志物(ROC AUC:0.829),最佳临界值为 73.1 mg/L(灵敏度:63.8%,特异性:88.5%)。NEUT-RI和NEUT-GI的准确性都很高,但准确性较差,ROC AUC分别为0.606和0.637:结论:Sysmex XN 系列分析仪所报告的新型实验室检测项目在鉴别复杂性阑尾炎方面的准确性较差。在这项研究中,CRP是性能最高的生物标志物,可用于预测急性阑尾炎的严重程度。
{"title":"Usefulness of extended inflammatory parameters related to neutrophil activation reported by Sysmex XN-1000 hematology analyzer for predicting complicated acute appendicitis. Comparison with canonical inflammatory laboratory tests","authors":"María Isabel Díaz López ,&nbsp;Elena Crespo Álvarez ,&nbsp;Álvaro Martínez Manzano ,&nbsp;Eloísa Urrechaga ,&nbsp;Manuel Tomás Orgaz Morales ,&nbsp;Mercedes González Morales ,&nbsp;Elena Martín García ,&nbsp;Luis García de Guadiana-Romualdo","doi":"10.1016/j.cireng.2023.11.022","DOIUrl":"10.1016/j.cireng.2023.11.022","url":null,"abstract":"<div><h3>Aim</h3><p>Accurate diagnosis of complicated appendicitis is of importance to ensure that patients receive early and effective treatment, minimizing the risk of postoperative complications to promote successful recovery. Biochemical markers are a promising tool to identify complicated appendicitis. We aimed to evaluate the potential role of novel parameters related with neutrophil activation, known as “<em>Extended Inflammation Parameters</em>” (EIP), included in blood cell count reported by Sysmex XN-Series analyzers, compared to other canonical biomarkers in identifying complicated appendicitis.</p></div><div><h3>Method</h3><p>Prospective observational study including patients with confirmed diagnosis of acute appendicitis. C-reactive protein (CRP), procalcitonin, cell blood count, including white blood cell (WBC), absolute neutrophil (ANC) and immature granulocyte (IG) count and EIP (neutrophil reactivity [NEUT-RI] and granularity intensity [NEUT-GI]) were analyzed before surgery. Their accuracy to diagnose complicated appendicitis was tested in an ROC curve analysis.</p></div><div><h3>Results</h3><p>Our population study included 119 patients, and appendicitis was complicated in 58 (48.7%). NLR, CRP and procalcitonin levels, ANC and IG count and NEUT-RI and NEUT-GI were higher in patients with complicated appendicitis. Regarding accuracy for complicated appendicitis, CRP was the biomarker with the highest performance (ROC AUC: 0.829), with an optimal cutoff of 73.1 mg/L (sensitivity: 63.8%, specificity: 88.5%). NEUT-RI and NEUT-GI achieved both significant but poor accuracy, with ROC AUC of 0.606 and 0.637, respectively.</p></div><div><h3>Conclusions</h3><p>Novel laboratory tests reported by Sysmex XN-Series analyzers have poor accuracy for identifying complicated appendicitis. In this study, CRP was the biomarker with the highest performance and may be useful as predictor of the severity of acute appendicitis.</p></div>","PeriodicalId":93935,"journal":{"name":"Cirugia espanola","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139718137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Cirugia espanola
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