首页 > 最新文献

Gait & posture最新文献

英文 中文
Subtalar joint axis alignments in pathological feet of children with cerebral palsy 脑瘫患儿病理性足的距下关节轴排列
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.152
Erik Meilak, Ruud Wellenberg, Wouter Schallig, Andrew Roberts, Melinda Witbreuk, Annemieke Buizer, Mario Maas, Marjolein van der Krogt, Luca Modenese, Caroline Stewart
Children suffering cerebral palsy (CP) often develop foot deformities [1]. These manifest as pathological postures including equinovarus, planovalgus non-midfoot break (PNMFB) and midfoot break (MFB) [2]. Although the mechanism for the development of foot deformity is poorly understood, recent research has highlighted how sensitive muscle moment arms [3] and joint moments are to the orientation of the subtalar joint (STJ) axis. Both are contributors to foot deformity. Studies have demonstrated a large variability in STJ axis orientations in healthy populations [4] and it is hypothesised that the variability in deformed feet will be even higher and correlate with specific deformities. How do STJ axis orientations in CP children with equinovarus, PNMFB and MFB deformities compare with typically developing children? Weight bearing (WB) and non-weight bearing (NWB) cone beam CT images of 21 feet from 17 CP patients (8 equinovarus, 7 PNMFB, 6 MFB, aged 12-17) and 7 feet from 7 typically-developing controls (aged 7-16) were acquired using a Verity (Planmed Oy) and Multitom Rax (Siemens) CBCT systems. Foot bones were semi-automatically segmented using Mimics 24.0, Materialize or Disior Bonelogic and remeshed to 1.0 mm isotropic edge length (OpenFlipper 4.1). Using the STAPLE pipeline [5], spheres were fitted to the talar head and talocalcaneal articulating surfaces and a cylinder to the talocrural articulating surface. STJ axis was approximated by the line joining the two fitted spheres [6]. The talocrural joint axis was approximated by the cylinder fitted to the talocrural articulating surface. An anterior-posterior (AP) line was calculated as the cross product of the ground normal and the talocrural joint axis. For each participant, STJ axis medial deviation and inclination from the AP line was calculated. A 2-sample t-test was used to test for statistically significant differences between groups. Mean STJ axis orientation in healthy participants was 23.2±5.7° (inclination) and 22.0±4.3° (medial deviation, Fig. 1). Inclinations varied from 31.4±6.3° for equinovarus feet to 20.2±4.2 for PNMFB and 4.0±10.6° for MFB patients. Mean medial deviations were 32.7±10.5° (equinovarus), 25.4±6.5° (PNMFB), and 28.8±4.5° (MFB). Both MFB and equinovarus groups exhibited STJ axis medial deviation angles greater than healthy controls. However, where the equinovarus group demonstrated 8.2° (p<0.05) greater inclination angle than the healthy controls, the MFB feet exhibited inclination angles 19.2° lower (p<0.05).Download : Download high-res image (99KB)Download : Download full-size image Although the analysis shows clear groupings in STJ axis orientations, further analyses of a greater range of CP pathological feet are needed to confirm these differences between groups. The abnormal STJ axis orientations of the deformed feet imply that abnormal moments are present during gait, further contributing to deformity. In conclusion, there is a measurable difference between t
脑瘫(CP)患儿常出现足部畸形[1]。这些表现为病态姿势,包括马蹄内翻、平外翻非足中骨折(PNMFB)和足中骨折(MFB)[2]。尽管足部畸形发展的机制尚不清楚,但最近的研究强调了肌肉力矩臂[3]和关节力矩对距下关节(STJ)轴方向的敏感程度。两者都是导致足部畸形的原因。研究表明,健康人群中STJ轴方向有很大的变异性[4],假设畸形足的变异性甚至更高,并与特定的畸形相关。CP伴马内翻、PNMFB和MFB畸形患儿与正常发育患儿相比,STJ轴方向如何?使用Verity (Planmed Oy)和Multitom Rax (Siemens) CBCT系统获取17例CP患者(8例马蹄内翻,7例PNMFB, 6例MFB,年龄12-17岁)21英尺的负重(WB)和非负重(NWB)锥束CT图像,以及7例正常发育对照(7-16岁)7英尺的锥形束CT图像。使用Mimics 24.0, Materialize或Disior bonlogic对足骨进行半自动分割,并重新网格化到1.0 mm各向同性边缘长度(OpenFlipper 4.1)。使用STAPLE管道[5],将球体安装到距骨头和距骨跟关节面,并将圆柱体安装到距骨胫部关节面。STJ轴近似为两个拟合球体的连接线[6]。用装配在距骨关节面上的圆柱体近似距骨关节轴。前后(AP)线作为地法线与距膝关节轴的叉积计算。对于每个参与者,计算STJ轴内侧偏离和AP线的倾斜度。采用双样本t检验检验组间差异是否具有统计学意义。健康参与者的平均STJ轴方向为23.2±5.7°(倾斜)和22.0±4.3°(内侧偏差,图1)。倾斜从马内翻足的31.4±6.3°到PNMFB的20.2±4.2°和MFB患者的4.0±10.6°不等。平均内侧偏度为32.7±10.5°(马内翻),25.4±6.5°(PNMFB)和28.8±4.5°(MFB)。MFB组和马蹄内翻组的STJ轴内侧偏角均大于健康对照组。然而,马蹄内翻组的足倾角比健康对照组大8.2°(p<0.05),而MFB组的足倾角比健康对照组小19.2°(p<0.05)。虽然分析在STJ轴方向上显示了明确的分组,但需要进一步分析更大范围的CP病理足来确认组间的差异。畸形足的STJ轴方向异常意味着步态中存在异常时刻,进一步导致畸形。总之,病理CP与健康足的STJ取向存在可测量的差异。了解这些差异是如何导致畸形的,将有助于制定有效的干预措施。
{"title":"Subtalar joint axis alignments in pathological feet of children with cerebral palsy","authors":"Erik Meilak, Ruud Wellenberg, Wouter Schallig, Andrew Roberts, Melinda Witbreuk, Annemieke Buizer, Mario Maas, Marjolein van der Krogt, Luca Modenese, Caroline Stewart","doi":"10.1016/j.gaitpost.2023.07.152","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.152","url":null,"abstract":"Children suffering cerebral palsy (CP) often develop foot deformities [1]. These manifest as pathological postures including equinovarus, planovalgus non-midfoot break (PNMFB) and midfoot break (MFB) [2]. Although the mechanism for the development of foot deformity is poorly understood, recent research has highlighted how sensitive muscle moment arms [3] and joint moments are to the orientation of the subtalar joint (STJ) axis. Both are contributors to foot deformity. Studies have demonstrated a large variability in STJ axis orientations in healthy populations [4] and it is hypothesised that the variability in deformed feet will be even higher and correlate with specific deformities. How do STJ axis orientations in CP children with equinovarus, PNMFB and MFB deformities compare with typically developing children? Weight bearing (WB) and non-weight bearing (NWB) cone beam CT images of 21 feet from 17 CP patients (8 equinovarus, 7 PNMFB, 6 MFB, aged 12-17) and 7 feet from 7 typically-developing controls (aged 7-16) were acquired using a Verity (Planmed Oy) and Multitom Rax (Siemens) CBCT systems. Foot bones were semi-automatically segmented using Mimics 24.0, Materialize or Disior Bonelogic and remeshed to 1.0 mm isotropic edge length (OpenFlipper 4.1). Using the STAPLE pipeline [5], spheres were fitted to the talar head and talocalcaneal articulating surfaces and a cylinder to the talocrural articulating surface. STJ axis was approximated by the line joining the two fitted spheres [6]. The talocrural joint axis was approximated by the cylinder fitted to the talocrural articulating surface. An anterior-posterior (AP) line was calculated as the cross product of the ground normal and the talocrural joint axis. For each participant, STJ axis medial deviation and inclination from the AP line was calculated. A 2-sample t-test was used to test for statistically significant differences between groups. Mean STJ axis orientation in healthy participants was 23.2±5.7° (inclination) and 22.0±4.3° (medial deviation, Fig. 1). Inclinations varied from 31.4±6.3° for equinovarus feet to 20.2±4.2 for PNMFB and 4.0±10.6° for MFB patients. Mean medial deviations were 32.7±10.5° (equinovarus), 25.4±6.5° (PNMFB), and 28.8±4.5° (MFB). Both MFB and equinovarus groups exhibited STJ axis medial deviation angles greater than healthy controls. However, where the equinovarus group demonstrated 8.2° (p<0.05) greater inclination angle than the healthy controls, the MFB feet exhibited inclination angles 19.2° lower (p<0.05).Download : Download high-res image (99KB)Download : Download full-size image Although the analysis shows clear groupings in STJ axis orientations, further analyses of a greater range of CP pathological feet are needed to confirm these differences between groups. The abnormal STJ axis orientations of the deformed feet imply that abnormal moments are present during gait, further contributing to deformity. In conclusion, there is a measurable difference between t","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135297890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medial gastrocnemius muscle morphology in spastic cerebral palsy: A comparison between treatment naïve children and children with a treatment history 痉挛型脑瘫患儿内侧腓肠肌形态:治疗naïve患儿与有治疗史患儿的比较
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.261
Fenna Walhain, Britta Hanssen, Rhea Spong-Cruden, Delaja Plein, Chelsi Bardan, Ruby Chin A Fat, Marlies Declerck, Lynn Bar-On, Anja Van Campenhout, Kaat Desloovere
In children with spastic cerebral palsy (SCP), conservative interventions such as physiotherapy, intra-muscular Botulinum Neurotoxin-A (BoNT-A) and serial casting are applied to counteract neuromuscular impairments [1]. The accumulated effects of these treatments on alterations in macroscopic muscle morphology are difficult to evaluate [2]. In Suriname, the access to these treatments for SCP-children is limited. Studying a cohort of treatment-naïve children, in comparison to a group of children with treatment history, can gain insight in the natural course of altered muscle morphology. Are the medial gastrocnemius (MG) macroscopic muscle morphology alterations different between treatment-naïve SCP children and SCP children with treatment history? In this cross-country comparison study, 20 treatment-naïve children from Suriname were case-control matched by age, GMFCS level and topographical description with 20 SCP-children with treatment history from Belgium. In addition, the data from 20 age-matched typically developing (TD) children from Belgium and 20 age-matched TD children from Suriname were assessed for comparison. A child was treatment-naïve if there was no previous 1) lower limb surgery, 2) serial casting in the last 3 years, 3) lower limb Botulinum Neurotoxin type A (BoNT-A) injection, 4) orthoses and 5) more than 10 physiotherapy sessions a year. SCP children had treatment history if they received usual care including orthoses and regular physiotherapy, and had access to BoNT-A treatment if clinically needed. Children with treatment history were excluded if they had 1) soft-tissue surgery, 2) BoNT-A injection in the last 10 months, 3) lower limb bony surgery in the last 2 years, 4) neurosurgery or 5) baclofen pump. Muscle-tendon unit (MTU) length, muscle length, tendon length and muscle volume were acquired from the MG with 3D freehand ultrasound measurement, which has proven reliability and validity [3]. Similar equipment, acquisition and processing procedures were used in both countries. The morphological alterations of the SCP child were calculated as a percentage of the morphology of the locally matched TD child. The medians and interquartile ranges of the deviation in morphology were defined, and treatment-naïve SCP-children and children with treatment history were compared by a Mann-Whitney U test. Both, the treatment-naïve and treatment-history groups showed alterations in their MG-muscle morphology compared to TD with greatest deviations in muscle volume (-47(19)% versus -31(30)%, Table 1). However, there were no significant differences in alterations for muscle volume, muscle length, tendon length and MTU length between treatment-naïve children and children with treatment history.Download : Download high-res image (167KB)Download : Download full-size image The natural course of pathological muscle morphology in treatment-naïve SCP-children seems comparable to SCP-children with treatment history. This may imply that the effect of
对于痉挛性脑瘫(SCP)患儿,保守性干预如物理治疗、肌内肉毒杆菌神经毒素- a (BoNT-A)和连续铸型等可用于对抗神经肌肉损伤[1]。这些治疗对宏观肌肉形态改变的累积效应很难评估[2]。在苏里南,scp儿童获得这些治疗的机会有限。研究一组treatment-naïve儿童,与一组有治疗史的儿童进行比较,可以深入了解肌肉形态改变的自然过程。treatment-naïve SCP患儿和有治疗史的SCP患儿的内侧腓肠肌(MG)宏观肌肉形态改变是否不同?在这项跨国比较研究中,来自苏里南的20名treatment-naïve儿童与来自比利时的20名有治疗史的scp儿童进行年龄、GMFCS水平和地形描述匹配的病例对照研究。此外,对来自比利时的20名年龄匹配的典型发育(TD)儿童和来自苏里南的20名年龄匹配的TD儿童的数据进行了评估以进行比较。如果以前没有做过1)下肢手术,2)过去3年连续铸造,3)下肢A型肉毒杆菌神经毒素(BoNT-A)注射,4)矫形器和5)每年10次以上物理治疗,则儿童为treatment-naïve。如果接受常规护理,包括矫形器和常规物理治疗,SCP儿童有治疗史,如果临床需要,可以接受BoNT-A治疗。排除有治疗史的儿童:1)软组织手术,2)近10个月BoNT-A注射,3)近2年下肢骨手术,4)神经外科手术或5)巴氯芬泵。通过三维徒手超声测量MG的肌腱单位(MTU)长度、肌长、肌腱长度和肌肉体积,证明了该方法的可靠性和有效性[3]。这两个国家都使用了类似的设备、采购和加工程序。SCP患儿的形态学改变计算为局部匹配的TD患儿形态学的百分比。定义形态学偏差的中位数和四分位数范围,并将treatment-naïve患儿与有治疗史的患儿进行Mann-Whitney U检验比较。与TD相比,treatment-naïve组和治疗史组的mg -肌形态都发生了变化,肌肉体积偏差最大(-47(19)%对-31(30)%,表1)。然而,treatment-naïve组和有治疗史的儿童在肌肉体积、肌肉长度、肌腱长度和MTU长度的变化方面没有显著差异。下载:下载高分辨率图片(167KB)下载:下载全尺寸图片treatment-naïve scp -儿童病理肌肉形态的自然过程似乎与有治疗史的scp -儿童相似。这可能意味着干预的效果不会显著影响肌肉病理形态。然而,数据的异质性要求在解释时谨慎。进一步的分析可能会揭示这些治疗对神经肌肉损伤和步态病理的累积效应。
{"title":"Medial gastrocnemius muscle morphology in spastic cerebral palsy: A comparison between treatment naïve children and children with a treatment history","authors":"Fenna Walhain, Britta Hanssen, Rhea Spong-Cruden, Delaja Plein, Chelsi Bardan, Ruby Chin A Fat, Marlies Declerck, Lynn Bar-On, Anja Van Campenhout, Kaat Desloovere","doi":"10.1016/j.gaitpost.2023.07.261","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.261","url":null,"abstract":"In children with spastic cerebral palsy (SCP), conservative interventions such as physiotherapy, intra-muscular Botulinum Neurotoxin-A (BoNT-A) and serial casting are applied to counteract neuromuscular impairments [1]. The accumulated effects of these treatments on alterations in macroscopic muscle morphology are difficult to evaluate [2]. In Suriname, the access to these treatments for SCP-children is limited. Studying a cohort of treatment-naïve children, in comparison to a group of children with treatment history, can gain insight in the natural course of altered muscle morphology. Are the medial gastrocnemius (MG) macroscopic muscle morphology alterations different between treatment-naïve SCP children and SCP children with treatment history? In this cross-country comparison study, 20 treatment-naïve children from Suriname were case-control matched by age, GMFCS level and topographical description with 20 SCP-children with treatment history from Belgium. In addition, the data from 20 age-matched typically developing (TD) children from Belgium and 20 age-matched TD children from Suriname were assessed for comparison. A child was treatment-naïve if there was no previous 1) lower limb surgery, 2) serial casting in the last 3 years, 3) lower limb Botulinum Neurotoxin type A (BoNT-A) injection, 4) orthoses and 5) more than 10 physiotherapy sessions a year. SCP children had treatment history if they received usual care including orthoses and regular physiotherapy, and had access to BoNT-A treatment if clinically needed. Children with treatment history were excluded if they had 1) soft-tissue surgery, 2) BoNT-A injection in the last 10 months, 3) lower limb bony surgery in the last 2 years, 4) neurosurgery or 5) baclofen pump. Muscle-tendon unit (MTU) length, muscle length, tendon length and muscle volume were acquired from the MG with 3D freehand ultrasound measurement, which has proven reliability and validity [3]. Similar equipment, acquisition and processing procedures were used in both countries. The morphological alterations of the SCP child were calculated as a percentage of the morphology of the locally matched TD child. The medians and interquartile ranges of the deviation in morphology were defined, and treatment-naïve SCP-children and children with treatment history were compared by a Mann-Whitney U test. Both, the treatment-naïve and treatment-history groups showed alterations in their MG-muscle morphology compared to TD with greatest deviations in muscle volume (-47(19)% versus -31(30)%, Table 1). However, there were no significant differences in alterations for muscle volume, muscle length, tendon length and MTU length between treatment-naïve children and children with treatment history.Download : Download high-res image (167KB)Download : Download full-size image The natural course of pathological muscle morphology in treatment-naïve SCP-children seems comparable to SCP-children with treatment history. This may imply that the effect of","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can we predict lower extremity motor control problems from single leg standing test for children with cerebral palsy? 脑瘫儿童单腿站立试验能否预测其下肢运动控制问题?
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.179
Kubra Onerge, Mervenur Arslan, Nazif Ekin Akalan, Rukiye Sert, Halenur Evrendilek
Selective voluntary motor control (SVMC) is a major contributor to motor function, balance, and gait performance in spastic cerebral palsy (SCP)(1). Single-leg standing (SLS) is a simple test to measure static balance which is highly correlated(2) and affected by impaired voluntary control in SCP(3). Therefore, a rapid and effective clinical evaluation of SVMC is of great importance. The aim of the study is to test whether SVMC assessment can be performed during SLS. May lower extremity SVMC be predicted during SLS in children with SCP? A total of 42 limbs of 11 children with SCP (6 females, 6 bilateral, 5 unilateral, 17 affected limbs; 11.33 ± 3.13 y.o, 39.14 ± 12.42 kg, 141.86 ± 14.46 cm) and 10 typically developed (TD) controls (4 females; 12.04 ± 3.16 y.o, 44.42 ± 16.12 kg, 151.88 ± 16.56 cm) were assessed in the study. The Selective Control Assessment of the Lower Extremity (SCALE) tool was used to measure SVMC(4). Hip, knee, and ankle movements were evaluated with a 3-point likert scale (2: normal, 1: impaired, 0: unable) at the monarthric level. In order to predict SVMC during SLS, the participants were videotaped while standing on a flat surface on one limb for as long as they could without any support by a smartphone (Xiaomi Redmi 10,50 MP) with a tripod placed at knee-level height (anterolaterally 45°). The longest SLS (max 10 sec.) of the three separate video recordings was evaluated. Similar to the SCALE, a 0-1-2 scoring system was developed to assess each joint’s SVMC during SLS: (2: the expected movements to maintain balance, 1: partial movements to maintain stability, 0: no compensated movement). 4 pediatric physical therapists with 7+ years of experience scored the videos 2 times in total, 1 week apart. The intra-rater and inter-rater reliability were statistically analyzed with intraclass correlation coefficients (ICC) and corresponding 95% confidence intervals (CI)(p<0.05)(5). Intra-rater reliability ICC correlation was excellent level at the subtalar-joint, good level at the ankle and toes, moderate level at the knee, and poor level at the hip were found between SVMC and SLS (Table-1). Also, significantly good to excellent inter-rater reliability (from 0.619 to 0.911) was found between SLS and SVMC (p<0.001). Download : Download high-res image (195KB)Download : Download full-size image The video-based SLS novel assessment methodology in this study succeeded to have a good to excellent correlation on SVMC on foot (ankle-subtalar-toe) joint level which was moderately correlated with appropriate ankle dorsiflexion at late swing(6). Movement assessment during SLS may give so much information about the quality of SVMC at the ankle-foot level which is the most related item with the gait abnormality. The research team is currently continuing to increase the sample size by including more participants and train more raters with a simple form and/or videos.
选择性随意运动控制(SVMC)是痉挛性脑瘫(SCP)患者运动功能、平衡和步态表现的主要因素(1)。单腿站立(SLS)是一种测量静态平衡的简单测试,静态平衡与SCP高度相关(2),并受其自主控制受损(3)的影响。因此,对SVMC进行快速有效的临床评价具有重要意义。本研究的目的是测试是否可以在SLS期间进行SVMC评估。重度瘫痪儿童在SLS中是否可以预测下肢SVMC ?11例SCP患儿共42肢(女性6例,双侧6例,单侧5例,患肢17例;11.33±3.13岁,39.14±12.42 kg, 141.86±14.46 cm)和10只典型发育(TD)对照(雌性4只;分别为12.04±3.16 y.o, 44.42±16.12 kg, 151.88±16.56 cm)。使用下肢选择性控制评估(SCALE)工具测量SVMC(4)。髋关节、膝关节和踝关节的运动以3点李克特量表(2:正常,1:受损,0:不能)在关节水平进行评估。为了预测SLS期间的SVMC,参与者在没有任何智能手机(小米红米10,50 MP)的支持下,用三脚架放置在膝盖高度(前外侧45°)的情况下,用一条腿站在平坦的表面上,尽可能长时间地进行录像。评估三个独立录像中最长的SLS(最大10秒)。与SCALE类似,开发了一个0-1-2评分系统来评估SLS期间每个关节的SVMC:(2:保持平衡的预期运动,1:保持稳定的部分运动,0:无补偿运动)。4名具有7年以上经验的儿童物理治疗师对视频进行评分,共2次,间隔1周。用类内相关系数(ICC)和相应的95%置信区间(CI)对评分者和评分者之间的信度进行统计分析(p<0.05)(5)。SVMC和SLS之间的量表内信度ICC相关性在距下关节处为优秀水平,在踝关节和脚趾处为良好水平,在膝关节处为中等水平,在髋关节处为差水平(表1)。此外,在SLS和SVMC之间发现显著良好到优异的评分间信度(从0.619到0.911)(p<0.001)。本研究中基于视频的SLS新评估方法成功地与足部(踝关节-距下-脚趾)关节水平的SVMC有良好到极好的相关性,并与后期摆动时适当的踝关节背屈适度相关(6)。SLS中的运动评估可以提供踝足水平SVMC质量的大量信息,这是与步态异常最相关的项目。研究小组目前正在继续增加样本量,包括更多的参与者,并通过简单的表格和/或视频培训更多的评分员。
{"title":"Can we predict lower extremity motor control problems from single leg standing test for children with cerebral palsy?","authors":"Kubra Onerge, Mervenur Arslan, Nazif Ekin Akalan, Rukiye Sert, Halenur Evrendilek","doi":"10.1016/j.gaitpost.2023.07.179","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.179","url":null,"abstract":"Selective voluntary motor control (SVMC) is a major contributor to motor function, balance, and gait performance in spastic cerebral palsy (SCP)(1). Single-leg standing (SLS) is a simple test to measure static balance which is highly correlated(2) and affected by impaired voluntary control in SCP(3). Therefore, a rapid and effective clinical evaluation of SVMC is of great importance. The aim of the study is to test whether SVMC assessment can be performed during SLS. May lower extremity SVMC be predicted during SLS in children with SCP? A total of 42 limbs of 11 children with SCP (6 females, 6 bilateral, 5 unilateral, 17 affected limbs; 11.33 ± 3.13 y.o, 39.14 ± 12.42 kg, 141.86 ± 14.46 cm) and 10 typically developed (TD) controls (4 females; 12.04 ± 3.16 y.o, 44.42 ± 16.12 kg, 151.88 ± 16.56 cm) were assessed in the study. The Selective Control Assessment of the Lower Extremity (SCALE) tool was used to measure SVMC(4). Hip, knee, and ankle movements were evaluated with a 3-point likert scale (2: normal, 1: impaired, 0: unable) at the monarthric level. In order to predict SVMC during SLS, the participants were videotaped while standing on a flat surface on one limb for as long as they could without any support by a smartphone (Xiaomi Redmi 10,50 MP) with a tripod placed at knee-level height (anterolaterally 45°). The longest SLS (max 10 sec.) of the three separate video recordings was evaluated. Similar to the SCALE, a 0-1-2 scoring system was developed to assess each joint’s SVMC during SLS: (2: the expected movements to maintain balance, 1: partial movements to maintain stability, 0: no compensated movement). 4 pediatric physical therapists with 7+ years of experience scored the videos 2 times in total, 1 week apart. The intra-rater and inter-rater reliability were statistically analyzed with intraclass correlation coefficients (ICC) and corresponding 95% confidence intervals (CI)(p<0.05)(5). Intra-rater reliability ICC correlation was excellent level at the subtalar-joint, good level at the ankle and toes, moderate level at the knee, and poor level at the hip were found between SVMC and SLS (Table-1). Also, significantly good to excellent inter-rater reliability (from 0.619 to 0.911) was found between SLS and SVMC (p<0.001). Download : Download high-res image (195KB)Download : Download full-size image The video-based SLS novel assessment methodology in this study succeeded to have a good to excellent correlation on SVMC on foot (ankle-subtalar-toe) joint level which was moderately correlated with appropriate ankle dorsiflexion at late swing(6). Movement assessment during SLS may give so much information about the quality of SVMC at the ankle-foot level which is the most related item with the gait abnormality. The research team is currently continuing to increase the sample size by including more participants and train more raters with a simple form and/or videos.","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender differences in distance between the talus and lateral malleolus during gait using ultrasound in healthy adults 健康成人超声步态中距骨和外踝距离的性别差异
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.242
Tsubasa Tashiro, Noriaki Maeda, Satoshi Onoue, Miki Kawai, Ayano Ishida, Shogo Tsutsumi, Satoshi Arima, Makoto Komiya, Yukio Urabe
The anterior talofibular ligament connects the talus to the lateral malleolus and is an essential component in understanding the pathophysiology of ankle sprains. In recent years, ultrasound is often used in its evaluation, however, most of it remains a static assessment (Rein S et al., 2020). Are there gender differences in the dynamics of the distance between the talus and the lateral malleolus during the stance phase of gait using ultrasound in healthy adults? The participants in this study were 10 healthy males and 9 healthy females. All participants did not report a history of previous ankle sprains. We used a motion capture system (Vicon Motion Systems, UK) synchronized with an ultrasound (Art Us EXT-1H, Telemed, Vilnius, Lithuania) to examine the distance between the talus and the lateral malleolus during the stance phase of gait. The US probe (5-11 MHz, 60-mm field of view; Echoblaster, Telemed, Vilnius, Lithuania) was positioned on the lateral side of the ankle joint and visualized the most lateral part of the talus and lateral malleolus on the ultrasound screen. Participants walked at a comfortable speed on a force plate (OR-6, 1000 Hz: AMTI, USA) and the interval from heel contact to toe-off was included in the analysis. Tracker 5.1.5 software (Open-Source Physics) was used to calculate the distance between the talus and lateral malleolus and the amount of change with respect to that distance at heel contact. Unpaired t-tests were used to compare the gender differences in that distance in the early, middle, and terminal stance phases. The changes in the distance between the talus and the lateral malleolus were -0.15±1.15 mm in the early stance phase, -0.98±1.99 mm in the middle stance phase, and -0.77±1.99 mm in the terminal stance phase in males and -0.84±0.92 mm, -2.24±1.40 mm, and -0.64±1.52 mm in women, respectively. The changes in the distance were significantly higher in females than in males in the early and middle stance phases. In females, the distance between the talus and the lateral malleolus during the stance phase of gait is highly variable, and this hypermobility may be a risk for ankle sprains and future ankle osteoarthritis. Prior study has reported that joint laxity is greater in women than in men after puberty, which may affect the incidence of injury (Quatman CE et al., 2008). This study using ultrasound could provide a basic data for examining ankle dynamics during gait in patients with ankle sprains.
距腓骨前韧带连接距骨和外踝,是了解踝关节扭伤病理生理学的重要组成部分。近年来,超声经常用于其评估,然而,大多数仍然是静态评估(Rein S et al., 2020)。在健康成人步态站立阶段使用超声观察距骨和外踝之间的距离是否存在性别差异?本研究的参与者为10名健康男性和9名健康女性。所有参与者都没有踝关节扭伤史。我们使用动作捕捉系统(Vicon motion Systems, UK)与超声波(Art Us EXT-1H, Telemed, Vilnius,立陶宛)同步来检查步态站立阶段距骨和外踝之间的距离。美国探头(5-11 MHz, 60毫米视场;Echoblaster, Telemed, Vilnius,立陶宛)定位于踝关节外侧,在超声屏幕上显示距骨和外踝的最外侧部分。参与者在力板上以舒适的速度行走(OR-6, 1000 Hz: AMTI, USA),从脚后跟接触到脚趾脱落的时间间隔也包括在分析中。使用Tracker 5.1.5软件(开源物理)计算距骨和外踝之间的距离以及脚跟接触时距离的变化量。使用非配对t检验比较在站立早期、中期和终末阶段的距离的性别差异。距骨与外踝之间的距离变化,男性站立前期-0.15±1.15 mm,站立中期-0.98±1.99 mm,站立末期-0.77±1.99 mm,女性分别为-0.84±0.92 mm, -2.24±1.40 mm, -0.64±1.52 mm。在站立前期和中期,女性的距离变化明显高于男性。在女性中,步态站立阶段距骨和外踝之间的距离是高度可变的,这种过度活动可能是踝关节扭伤和未来踝关节骨关节炎的风险。先前有研究报道,女性在青春期后的关节松弛程度大于男性,这可能会影响损伤的发生率(Quatman CE et al., 2008)。本研究可为踝关节扭伤患者步态过程中踝关节动力学的研究提供基础数据。
{"title":"Gender differences in distance between the talus and lateral malleolus during gait using ultrasound in healthy adults","authors":"Tsubasa Tashiro, Noriaki Maeda, Satoshi Onoue, Miki Kawai, Ayano Ishida, Shogo Tsutsumi, Satoshi Arima, Makoto Komiya, Yukio Urabe","doi":"10.1016/j.gaitpost.2023.07.242","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.242","url":null,"abstract":"The anterior talofibular ligament connects the talus to the lateral malleolus and is an essential component in understanding the pathophysiology of ankle sprains. In recent years, ultrasound is often used in its evaluation, however, most of it remains a static assessment (Rein S et al., 2020). Are there gender differences in the dynamics of the distance between the talus and the lateral malleolus during the stance phase of gait using ultrasound in healthy adults? The participants in this study were 10 healthy males and 9 healthy females. All participants did not report a history of previous ankle sprains. We used a motion capture system (Vicon Motion Systems, UK) synchronized with an ultrasound (Art Us EXT-1H, Telemed, Vilnius, Lithuania) to examine the distance between the talus and the lateral malleolus during the stance phase of gait. The US probe (5-11 MHz, 60-mm field of view; Echoblaster, Telemed, Vilnius, Lithuania) was positioned on the lateral side of the ankle joint and visualized the most lateral part of the talus and lateral malleolus on the ultrasound screen. Participants walked at a comfortable speed on a force plate (OR-6, 1000 Hz: AMTI, USA) and the interval from heel contact to toe-off was included in the analysis. Tracker 5.1.5 software (Open-Source Physics) was used to calculate the distance between the talus and lateral malleolus and the amount of change with respect to that distance at heel contact. Unpaired t-tests were used to compare the gender differences in that distance in the early, middle, and terminal stance phases. The changes in the distance between the talus and the lateral malleolus were -0.15±1.15 mm in the early stance phase, -0.98±1.99 mm in the middle stance phase, and -0.77±1.99 mm in the terminal stance phase in males and -0.84±0.92 mm, -2.24±1.40 mm, and -0.64±1.52 mm in women, respectively. The changes in the distance were significantly higher in females than in males in the early and middle stance phases. In females, the distance between the talus and the lateral malleolus during the stance phase of gait is highly variable, and this hypermobility may be a risk for ankle sprains and future ankle osteoarthritis. Prior study has reported that joint laxity is greater in women than in men after puberty, which may affect the incidence of injury (Quatman CE et al., 2008). This study using ultrasound could provide a basic data for examining ankle dynamics during gait in patients with ankle sprains.","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ankle power support of spring-like ankle foot orthoses and their effect on compensatory joint work 弹簧式踝足矫形器的踝关节动力支撑及其对关节补偿性工作的影响
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.265
Niels Waterval, Frans Nollet, Merel-Anne Brehm
{"title":"Ankle power support of spring-like ankle foot orthoses and their effect on compensatory joint work","authors":"Niels Waterval, Frans Nollet, Merel-Anne Brehm","doi":"10.1016/j.gaitpost.2023.07.265","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.265","url":null,"abstract":"","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Movement patterns are different but muscle activations are unchanged in women with patellofemoral pain 髌骨股痛患者的运动模式不同,但肌肉激活没有变化
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.240
Albuquerque Tadeu, Cintia Lopes Ferreira, Juliane Almeida, Barton Gabor, Paulo Lucareli
Patellofemoral pain (PFP) is one of the leading causes of knee pain. Changes in movement patterns and a possible relationship between movement patterns and muscle activation are commonly found in women with PFP [1]. The Movement Deviation Profile (MDP) showed differences in the movement pattern in women with PFP [2], however, to the best of our knowledge, the MDP was not used to differentiate the electromyography of women with and without PFP. This study aimed to verify whether the combined analysis of kinematics and EMG data increases the ability to differentiate between women with and without PFP compared to the independent analysis of kinematics and electromyographic activity. Is there a difference in movement patterns and muscle activation between women with and without PFP? Could the combination of EMG with kinematics data increase the ability to differentiate women with and without PFP? Seventy-one women, 37 with PFP and 34 unimpaired were selected for kinematic and EMG evaluation during the Lateral Step Down (LSD) task. For the 3D kinematics, movements in the sagittal, frontal and transverse planes of the trunk, pelvis and hip were used; sagittal and frontal planes of the knee; ankle sagittal plane; and the transverse plane of the foot in relation to the laboratory. For the EMG, filtered, rectified and smoothed signals from the adductor longus, gluteus medius, vastus lateralis and medialis, rectus femoris, biceps femoris, medial gastrocnemius and tibialis anterior muscles were used, which were normalised in amplitude to the average of the peaks of each cycle of LSD and in time by resampling the EMG envelopes every 1% of the LSD cycle. The MDP, which is a single number measure of movement deviation derived from a multidimensional neural network analysis, was used to analyse kinematics, EMG and kinematics combined with EMG. The Z-score of the MDPmean was calculated to compare the standardised results between women with and without PFP. A multivariate analysis with Bonferroni post-hoc test compared the groups considering p < 0.05. Multivariate analysis showed group interaction (l=0.838; F=4.329; p=0.008). There was a significant difference between groups in the MDPmean Z-Score only for kinematics (0.97). There was no difference between groups for EMG (0.44) and kinematics with EMG (0.39).Download : Download high-res image (117KB)Download : Download full-size image This study corroborates with the literature demonstrating that women with PFP present changes in the movement pattern but not in the amplitude of the electromyography. EMG, even when evaluating with a self-organising neural network (MDP), considering several muscles relevant to PFP, failed to differentiate between women with and without PFP both on its own or combined with kinematics. We conclude that, when using MDP, kinematics is the variable capable of differentiating women with and without PFP during LSD.
髌股疼痛(PFP)是膝关节疼痛的主要原因之一。运动模式的改变以及运动模式与肌肉激活之间的可能关系在PFP女性中很常见[1]。运动偏差谱(MDP)显示了PFP女性运动模式的差异[2],然而,据我们所知,MDP并没有被用来区分有和没有PFP的女性的肌电图。本研究旨在验证与运动学和肌电活动的独立分析相比,运动学和肌电数据的联合分析是否增加了区分有和没有PFP的女性的能力。有和没有PFP的女性在运动模式和肌肉激活上有什么不同吗?肌电图与运动学数据的结合是否能提高区分女性是否患有PFP的能力?选择71名女性,其中37名患有PFP, 34名未受损,在横向降压(LSD)任务中进行运动学和肌电图评估。对于三维运动学,使用躯干,骨盆和髋关节的矢状面,额面和横平面的运动;膝关节的矢状面和额平面;踝关节矢状面;以及脚的横切面与实验室的关系。肌电图使用来自长内收肌、臀中肌、股外侧肌和内侧肌、股直肌、股二头肌、腓肠肌内侧肌和胫前肌的信号进行滤波、整流和平滑处理,将其振幅归一为每个LSD周期峰值的平均值,并通过每1%的LSD周期重新采样肌电包膜及时归一。MDP是一种由多维神经网络分析得出的运动偏差的单数字测量方法,用于分析运动学、肌电图以及运动学与肌电图的结合。计算MDPmean的z分数来比较有PFP和没有PFP的妇女之间的标准化结果。采用Bonferroni事后检验进行多变量分析,考虑p < 0.05。多因素分析显示组间相互作用(l=0.838;F = 4.329;p = 0.008)。组间MDPmean Z-Score仅在运动学方面有显著差异(0.97)。肌电图(0.44)和运动图(0.39)组间无差异。本研究与文献证实,患有PFP的女性在运动模式上有变化,但在肌电图的振幅上没有变化。即使使用自组织神经网络(MDP)进行评估,考虑到与PFP相关的几块肌肉,肌电图也无法单独或结合运动学来区分有和没有PFP的女性。我们得出结论,当使用MDP时,运动学是能够在LSD期间区分有和没有PFP的女性的变量。
{"title":"Movement patterns are different but muscle activations are unchanged in women with patellofemoral pain","authors":"Albuquerque Tadeu, Cintia Lopes Ferreira, Juliane Almeida, Barton Gabor, Paulo Lucareli","doi":"10.1016/j.gaitpost.2023.07.240","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.240","url":null,"abstract":"Patellofemoral pain (PFP) is one of the leading causes of knee pain. Changes in movement patterns and a possible relationship between movement patterns and muscle activation are commonly found in women with PFP [1]. The Movement Deviation Profile (MDP) showed differences in the movement pattern in women with PFP [2], however, to the best of our knowledge, the MDP was not used to differentiate the electromyography of women with and without PFP. This study aimed to verify whether the combined analysis of kinematics and EMG data increases the ability to differentiate between women with and without PFP compared to the independent analysis of kinematics and electromyographic activity. Is there a difference in movement patterns and muscle activation between women with and without PFP? Could the combination of EMG with kinematics data increase the ability to differentiate women with and without PFP? Seventy-one women, 37 with PFP and 34 unimpaired were selected for kinematic and EMG evaluation during the Lateral Step Down (LSD) task. For the 3D kinematics, movements in the sagittal, frontal and transverse planes of the trunk, pelvis and hip were used; sagittal and frontal planes of the knee; ankle sagittal plane; and the transverse plane of the foot in relation to the laboratory. For the EMG, filtered, rectified and smoothed signals from the adductor longus, gluteus medius, vastus lateralis and medialis, rectus femoris, biceps femoris, medial gastrocnemius and tibialis anterior muscles were used, which were normalised in amplitude to the average of the peaks of each cycle of LSD and in time by resampling the EMG envelopes every 1% of the LSD cycle. The MDP, which is a single number measure of movement deviation derived from a multidimensional neural network analysis, was used to analyse kinematics, EMG and kinematics combined with EMG. The Z-score of the MDPmean was calculated to compare the standardised results between women with and without PFP. A multivariate analysis with Bonferroni post-hoc test compared the groups considering p < 0.05. Multivariate analysis showed group interaction (l=0.838; F=4.329; p=0.008). There was a significant difference between groups in the MDPmean Z-Score only for kinematics (0.97). There was no difference between groups for EMG (0.44) and kinematics with EMG (0.39).Download : Download high-res image (117KB)Download : Download full-size image This study corroborates with the literature demonstrating that women with PFP present changes in the movement pattern but not in the amplitude of the electromyography. EMG, even when evaluating with a self-organising neural network (MDP), considering several muscles relevant to PFP, failed to differentiate between women with and without PFP both on its own or combined with kinematics. We conclude that, when using MDP, kinematics is the variable capable of differentiating women with and without PFP during LSD.","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the degree of reliability in forensic gait analysis Methods 法医步态分析方法可靠性的比较
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.08.026
Alexia Patinioti, Georgios Gkrimas
{"title":"Comparison of the degree of reliability in forensic gait analysis Methods","authors":"Alexia Patinioti, Georgios Gkrimas","doi":"10.1016/j.gaitpost.2023.08.026","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.08.026","url":null,"abstract":"","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kinematic limitations during obstacle-crossing in adolescent idiopathic scoliosis 青少年特发性脊柱侧凸过障时的运动学限制
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.203
Maria Rassam, Karim Hoyek, Rony El Hayeck, Georges Haddad, Emmanuelle Wakim, Elio Mekhael, Nabil Nassim, Ismat Ghanem, Rami El Rachkidi, Ayman Assi
Scoliosis is a 3D spinal deformity that is known to affect patient’s alignment on static radiographs [1] and their movement during walking or other daily life activities [2]. Crossing obstacles is a common activity that can challenge patients’ stability. However, kinematics of the obstacle-crossing movement is still unknown in adolescent idiopathic scoliosis (AIS). Are kinematics affected in patients with AIS during obstacle-crossing? 18 AIS patients with major right convexity thoracic scoliosis (Cobb: 38° [25-55°]) and 15 controls (age and sex matched: 16 years, 85% F) underwent biplanar X-rays in standing position with the calculation of 3D radiographic spinopelvic parameters. 3D movement analysis was performed during obstacle-crossing, obstacle being fixed at 30% of lower limb length, and executed once with each leg leading the movement. Kinematic parameters of the head, trunk, pelvis, lower limbs and spinal segments were calculated [3,4]. Parameters were compared between the 2 groups and the relationship between kinematic and radiographic variables was investigated. During obstacle-crossing, AIS patients showed an increased thorax extension compared to controls (-19 vs 6°, p<0.05), especially in the main thoracic segment (T3T6-T6T9= 9 vs 14°, p<0.05). Conversely, AIS patients showed a decreased lumbar lordosis when compared to controls (T12L3-L3L5=-14 vs -20°, p<0.05). Moreover, AIS patients showed an anterior rotation (-2 vs 2°) and elevation (6 vs 0°, both p<0.05) of the right shoulder. Patients also showed a decreased hip abduction of the leading leg when compared to controls (-5 vs -9°, p<0.05). The main thoracic extension was correlated to the Cobb angle (r=-0.50) and the shoulder axial rotation to the apical vertebral rotation (r=0.75, both p<0.05; Fig. 1). AIS patients are known to have back flattening with a loss of lumbar lordosis due to their spinal deformity. This spinal malalignment was shown to persist dynamically during obstacle-crossing, associated with a forward shift and elevation of the convexity-side shoulder. The backward movement of the trunk and the shoulder rotation attitude, along with the decreased hip abduction, might hinder stability during obstacle-crossing. These kinematic alterations were shown to increase with the spinal deformity (increased Cobb and apical vertebral rotation). Future studies will investigate kinematic changes in AIS patients following spinal fusion. Fig. 1 Correlations between kinematic limitations and scoliosis severity in adolescent idiopathic scoliosis during obstacle-crossing movement.Download : Download high-res image (100KB)Download : Download full-size image
脊柱侧凸是一种三维脊柱畸形,已知会影响患者在静态x线片上的对齐[1]以及行走或其他日常生活活动时的运动[2]。穿越障碍是一项常见的活动,可能会挑战患者的稳定性。然而,青少年特发性脊柱侧凸(AIS)的过障运动的运动学尚不清楚。AIS患者过障时运动学会受到影响吗?18例患有严重右凸性胸侧凸的AIS患者(Cobb: 38°[25-55°])和15例对照(年龄和性别匹配:16岁,85% F)在站立位行双平面x线检查,计算脊柱骨盆三维x线参数。在过障过程中进行三维运动分析,障碍物固定在下肢长度的30%处,每条腿引领一次。计算头部、躯干、骨盆、下肢和脊柱节段的运动学参数[3,4]。比较两组间的参数,并研究运动学和影像学变量之间的关系。在过障过程中,AIS患者的胸伸度比对照组增加(-19°vs . 6°,p<0.05),尤其是在主胸段(T3T6-T6T9= 9°vs . 14°,p<0.05)。相反,与对照组相比,AIS患者腰椎前凸度降低(T12L3-L3L5=-14°vs -20°,p<0.05)。此外,AIS患者右肩前旋(-2°vs 2°)和上仰(6°vs 0°,均p<0.05)。与对照组相比,患者还表现出前腿髋外展减少(-5°vs -9°,p<0.05)。主胸伸展与Cobb角相关(r=-0.50),肩关节轴向旋转与椎体顶点旋转相关(r=0.75), p均<0.05;图1)众所周知,AIS患者由于脊柱畸形,背部扁平,腰椎前凸消失。这种脊柱错位在过障过程中持续存在,与凸侧肩关节前移和抬高有关。躯干向后运动和肩部旋转的姿态,以及髋外展的减少,可能会妨碍过障时的稳定性。这些运动学改变随着脊柱畸形的增加而增加(Cobb和椎体顶端旋转增加)。未来的研究将探讨AIS患者脊柱融合术后的运动学变化。图1青少年特发性脊柱侧凸在过障运动中运动受限与脊柱侧凸严重程度的相关性。下载:下载高清图片(100KB)下载:下载全尺寸图片
{"title":"Kinematic limitations during obstacle-crossing in adolescent idiopathic scoliosis","authors":"Maria Rassam, Karim Hoyek, Rony El Hayeck, Georges Haddad, Emmanuelle Wakim, Elio Mekhael, Nabil Nassim, Ismat Ghanem, Rami El Rachkidi, Ayman Assi","doi":"10.1016/j.gaitpost.2023.07.203","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.203","url":null,"abstract":"Scoliosis is a 3D spinal deformity that is known to affect patient’s alignment on static radiographs [1] and their movement during walking or other daily life activities [2]. Crossing obstacles is a common activity that can challenge patients’ stability. However, kinematics of the obstacle-crossing movement is still unknown in adolescent idiopathic scoliosis (AIS). Are kinematics affected in patients with AIS during obstacle-crossing? 18 AIS patients with major right convexity thoracic scoliosis (Cobb: 38° [25-55°]) and 15 controls (age and sex matched: 16 years, 85% F) underwent biplanar X-rays in standing position with the calculation of 3D radiographic spinopelvic parameters. 3D movement analysis was performed during obstacle-crossing, obstacle being fixed at 30% of lower limb length, and executed once with each leg leading the movement. Kinematic parameters of the head, trunk, pelvis, lower limbs and spinal segments were calculated [3,4]. Parameters were compared between the 2 groups and the relationship between kinematic and radiographic variables was investigated. During obstacle-crossing, AIS patients showed an increased thorax extension compared to controls (-19 vs 6°, p<0.05), especially in the main thoracic segment (T3T6-T6T9= 9 vs 14°, p<0.05). Conversely, AIS patients showed a decreased lumbar lordosis when compared to controls (T12L3-L3L5=-14 vs -20°, p<0.05). Moreover, AIS patients showed an anterior rotation (-2 vs 2°) and elevation (6 vs 0°, both p<0.05) of the right shoulder. Patients also showed a decreased hip abduction of the leading leg when compared to controls (-5 vs -9°, p<0.05). The main thoracic extension was correlated to the Cobb angle (r=-0.50) and the shoulder axial rotation to the apical vertebral rotation (r=0.75, both p<0.05; Fig. 1). AIS patients are known to have back flattening with a loss of lumbar lordosis due to their spinal deformity. This spinal malalignment was shown to persist dynamically during obstacle-crossing, associated with a forward shift and elevation of the convexity-side shoulder. The backward movement of the trunk and the shoulder rotation attitude, along with the decreased hip abduction, might hinder stability during obstacle-crossing. These kinematic alterations were shown to increase with the spinal deformity (increased Cobb and apical vertebral rotation). Future studies will investigate kinematic changes in AIS patients following spinal fusion. Fig. 1 Correlations between kinematic limitations and scoliosis severity in adolescent idiopathic scoliosis during obstacle-crossing movement.Download : Download high-res image (100KB)Download : Download full-size image","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of varus foot deformities on muscle moment arms in children with cerebral palsy 脑性麻痹患儿足内翻畸形对肌肉力矩臂的影响
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.256
Gaia Van Den Heuvel, Wouter Schallig, Marjolein van der Krogt, Ruud Wellenberg, Mario Maas, Annemieke Buizer, Ajay Seth
Children with cerebral palsy (CP) commonly develop deformities of the foot [1], which lead to pain and gait problems. One of the causes of such deformities is likely an imbalance in muscle forces around the foot [2]. In turn, these deformities can also alter muscle function due to altered muscle moment arms. Moment arms can be estimated using musculoskeletal models, but models based on generic bone geometry are unlikely to represent the deformity accurately. Weight-bearing computed tomography (WBCT) enables assessment of abnormal bone alignment under loaded conditions [3]. What are the changes in moment arm lengths of the main invertors and evertors (i.e. the tibialis and peroneal muscles) around the subtalar joint in children with cavovarus and equinovarus foot deformity due to CP? Six children with a severe hindfoot varus deformity due to CP (one female, aged 13.8 ± 2.3 years) and four typically developed (TD) adults (one female, aged 35.8 ± 4.8 years) were included. Personalized musculoskeletal foot models were created in OpenSim Creator [4] using WBCT scans. This foot was attached to the full-body OpenSim gait2392 model, which was scaled using gait analysis data. Muscle moment arms were calculated using OpenSim [5,6] and normalized to tibia length. A non-parametric Mann-Whitney U test was used to compare between groups. Normalized inversion-eversion moment arm lengths are shown in Fig. 1. The tibialis anterior had an inversion moment arm in the deformed CP feet, in contrast to an eversion moment arm in the TD group. No differences were found for the tibialis posterior. Although there was no overall group effect, the eversion moment arm of the peroneal muscles was smaller in most CP children compared to the TD group. Fig. 1 - Moment arms around the subtalar joint, normalized to tibia length. Note the different scales on the vertical axes. * p <.01.Download : Download high-res image (93KB)Download : Download full-size image We present the first study to evaluate altered moment arms in feet of children with CP using personalized musculoskeletal foot models based on WBCT scans. Our results indicate that the tibialis anterior becomes a more effective invertor with a varus deformity of the foot. Despite the fact that the tibialis posterior is often seen as an important cause of the varus deformity, its function as expressed by the moment arm does not change. On the other hand, the eversion moment arms of the peroneal muscles tend to become smaller, meaning they would be less effective in counterbalancing the deformity. Together, these altered moment arms would lead to an even larger varus moment in the subtalar joint with similar muscle forces, thereby pulling the foot even more towards varus. Our results could explain the progression of the deformity once the deformity is present.
患有脑瘫(CP)的儿童通常会出现足部畸形,从而导致疼痛和步态问题。造成这种畸形的原因之一可能是足部周围肌肉力量的不平衡。反过来,由于肌肉力臂的改变,这些畸形也会改变肌肉功能。力矩臂可以使用肌肉骨骼模型来估计,但基于一般骨骼几何的模型不太可能准确地表示畸形。负重计算机断层扫描(WBCT)可以评估负载条件下异常的骨排列[b]。CP引起的足内翻和马内翻畸形患儿距下关节周围主要内翻肌和外翻肌(即胫骨肌和腓骨肌)的力臂长度有什么变化?本研究包括6例由CP引起的严重后足内翻畸形儿童(1例女性,年龄13.8±2.3岁)和4例典型发育(TD)成人(1例女性,年龄35.8±4.8岁)。使用WBCT扫描在OpenSim Creator[4]中创建个性化的肌肉骨骼足模型。将这只脚连接到全身OpenSim gait2392模型上,使用步态分析数据对模型进行缩放。使用OpenSim计算肌肉力臂[5,6],并将其归一化为胫骨长度。采用非参数Mann-Whitney U检验进行组间比较。归一化倒转力矩臂长度如图1所示。与TD组的外翻力臂相比,畸形CP足的胫骨前肌有内翻力臂。胫骨后肌无明显差异。虽然没有整体的组效应,但与TD组相比,大多数CP儿童的腓骨肌外翻力矩臂较小。图1 -距下关节周围的力臂,与胫骨长度标准化。请注意垂直轴上的不同刻度。* p < 0.01。下载:下载:下载全尺寸图片我们首次使用基于WBCT扫描的个性化足部肌肉骨骼模型来评估CP儿童足部力臂的改变。我们的结果表明,胫骨前肌成为一个更有效的倒置与足内翻畸形。尽管胫骨后肌通常被认为是内翻畸形的重要原因,但它的功能通过力臂表达并没有改变。另一方面,腓肌的外翻力矩臂往往会变小,这意味着它们在平衡畸形方面的效果会降低。总之,这些改变的力臂会导致距下关节在类似的肌肉力量下产生更大的内翻力矩,从而将脚进一步拉向内翻。我们的结果可以解释一旦畸形出现,畸形的进展。
{"title":"The effect of varus foot deformities on muscle moment arms in children with cerebral palsy","authors":"Gaia Van Den Heuvel, Wouter Schallig, Marjolein van der Krogt, Ruud Wellenberg, Mario Maas, Annemieke Buizer, Ajay Seth","doi":"10.1016/j.gaitpost.2023.07.256","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.256","url":null,"abstract":"Children with cerebral palsy (CP) commonly develop deformities of the foot [1], which lead to pain and gait problems. One of the causes of such deformities is likely an imbalance in muscle forces around the foot [2]. In turn, these deformities can also alter muscle function due to altered muscle moment arms. Moment arms can be estimated using musculoskeletal models, but models based on generic bone geometry are unlikely to represent the deformity accurately. Weight-bearing computed tomography (WBCT) enables assessment of abnormal bone alignment under loaded conditions [3]. What are the changes in moment arm lengths of the main invertors and evertors (i.e. the tibialis and peroneal muscles) around the subtalar joint in children with cavovarus and equinovarus foot deformity due to CP? Six children with a severe hindfoot varus deformity due to CP (one female, aged 13.8 ± 2.3 years) and four typically developed (TD) adults (one female, aged 35.8 ± 4.8 years) were included. Personalized musculoskeletal foot models were created in OpenSim Creator [4] using WBCT scans. This foot was attached to the full-body OpenSim gait2392 model, which was scaled using gait analysis data. Muscle moment arms were calculated using OpenSim [5,6] and normalized to tibia length. A non-parametric Mann-Whitney U test was used to compare between groups. Normalized inversion-eversion moment arm lengths are shown in Fig. 1. The tibialis anterior had an inversion moment arm in the deformed CP feet, in contrast to an eversion moment arm in the TD group. No differences were found for the tibialis posterior. Although there was no overall group effect, the eversion moment arm of the peroneal muscles was smaller in most CP children compared to the TD group. Fig. 1 - Moment arms around the subtalar joint, normalized to tibia length. Note the different scales on the vertical axes. * p <.01.Download : Download high-res image (93KB)Download : Download full-size image We present the first study to evaluate altered moment arms in feet of children with CP using personalized musculoskeletal foot models based on WBCT scans. Our results indicate that the tibialis anterior becomes a more effective invertor with a varus deformity of the foot. Despite the fact that the tibialis posterior is often seen as an important cause of the varus deformity, its function as expressed by the moment arm does not change. On the other hand, the eversion moment arms of the peroneal muscles tend to become smaller, meaning they would be less effective in counterbalancing the deformity. Together, these altered moment arms would lead to an even larger varus moment in the subtalar joint with similar muscle forces, thereby pulling the foot even more towards varus. Our results could explain the progression of the deformity once the deformity is present.","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between trunk muscle forces, static and dynamic postural malalignment in patients with adult spinal deformity 成人脊柱畸形患者躯干肌力、静态和动态体位失调的关系
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.214
Maria Saade, Ali Rteil, Rami El Rachkidi, Celine Chaaya, Elma Ayoub, Elena Jaber, Elio Mekhael, Nabil Nassim, Abir Massaad, Ayman Assi
Patients with Adult spinal Deformity (ASD) are known to have a deteriorated quality of life (QOL). Severe spinal deformity can develop into postural malalignment caused by a forward shift of the trunk and head. Recent studies have shown that sagittal malalignment in patients with ASD can affect joints and segments’ kinematics during daily life activities [1,2]. On the other hand, ASD patients are known to present with muscular degeneration [3]. However, it is still unknown how trunk muscle’s weakness can affect ASD postural alignment in static position and during daily life activities. To investigate the relationship between muscle forces, radiographic parameters, joint kinematics during daily activities, and QOL scores in ASD. 25 ASD & 19 controls underwent biplanar radiographs in both standing and sitting positions with the calculation of 3D classic spinopelvic and postural alignment parameters (i.e: SVA plumbline between C7 and posterior corner of the sacrum; ODHA angle between line joining odontoid process and middle of hip axis with the vertical). Movement analysis was performed during walking, sit-to-stand, and stair ascent-descent with the calculation of 3D joint and segment kinematics. Participants filled out QOL questionnaires (SF-36 with both physical and mental components, Oswestry Disability Index ODI). The strength of the following muscle groups was measured using a hand-held dynamometer: trunk extensors, flexors, and right & left lateral flexors. ASD were divided into 2 groups based on the age-normalized strength of trunk extensors compared to controls: ASD-normal extensors and ASD-weak extensors (having strength
已知成人脊柱畸形(ASD)患者的生活质量(QOL)恶化。严重的脊柱畸形可发展为由躯干和头部前移引起的姿势失调。最近的研究表明,ASD患者矢状面排列失调会影响日常生活活动中关节和节段的运动学[1,2]。另一方面,已知ASD患者表现为肌肉变性[3]。然而,躯干肌肉无力如何影响ASD在静态位置和日常生活活动中的姿势对齐仍然是未知的。探讨ASD患者肌肉力量、影像学参数、日常活动时关节运动学与生活质量评分之间的关系。25名ASD患者和19名对照组患者分别在站立和坐姿下接受双平面x线摄影,并计算三维经典的脊柱骨盆和体位对齐参数(即C7和骶骨后角之间的SVA垂直线;齿状突连接线与髋中轴之间的ODHA夹角(纵)。在行走、坐立和楼梯升降过程中进行运动分析,并计算三维关节和节段运动学。参与者填写生活质量问卷(SF-36,包括身体和精神部分,Oswestry残疾指数ODI)。使用手持式测力仪测量以下肌肉群的力量:躯干伸肌、屈肌和左右侧屈肌。根据与对照组相比躯干伸肌的年龄标准化强度将ASD分为两组:ASD正常伸肌组和ASD弱伸肌组(对照组强度<均值1sd)。比较两组间影像学参数、运动学变量和生活质量评分。6例ASD伸展肌弱(F=20,对照组为26)。与asd正常伸肌相比,asd弱伸肌患者在站立时呈前矢状排列(ODHA=5°vs 3°,SVA =73 mm vs 24 mm)。他们必须在坐着时增加骨盆后倾,以保持水平凝视(坐-骨盆倾斜=41°vs asd正常伸肌35°)。矢状面排列失调在不同的运动过程中持续存在(动态- odha =16°,而asd正常伸肌为9°)。然而,正常伸肌的ASD在放射学和运动学参数上的改变较小。肌无力与生活质量的恶化相关(物理成分- sf36: r=0.55;P <0.001),步行速度降低(r=0.44;p<0.001,图1)。该初步研究表明,弱躯干伸肌与站立和坐姿以及日常生活活动中的矢状位错位有关。弱伸肌也与ASD患者生活质量的恶化有关。躯干伸肌的正常力量似乎有助于ASD患者补偿他们在静态和运动时的脊柱畸形。未来的研究将探讨肌肉强化对ASD患者静态和动态对齐及其生活质量的影响。图1:躯干伸肌力量、生活质量评分与步行速度的相关性。下载:下载高分辨率图片(46KB)下载:下载全尺寸图片
{"title":"Relationship between trunk muscle forces, static and dynamic postural malalignment in patients with adult spinal deformity","authors":"Maria Saade, Ali Rteil, Rami El Rachkidi, Celine Chaaya, Elma Ayoub, Elena Jaber, Elio Mekhael, Nabil Nassim, Abir Massaad, Ayman Assi","doi":"10.1016/j.gaitpost.2023.07.214","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.214","url":null,"abstract":"Patients with Adult spinal Deformity (ASD) are known to have a deteriorated quality of life (QOL). Severe spinal deformity can develop into postural malalignment caused by a forward shift of the trunk and head. Recent studies have shown that sagittal malalignment in patients with ASD can affect joints and segments’ kinematics during daily life activities [1,2]. On the other hand, ASD patients are known to present with muscular degeneration [3]. However, it is still unknown how trunk muscle’s weakness can affect ASD postural alignment in static position and during daily life activities. To investigate the relationship between muscle forces, radiographic parameters, joint kinematics during daily activities, and QOL scores in ASD. 25 ASD & 19 controls underwent biplanar radiographs in both standing and sitting positions with the calculation of 3D classic spinopelvic and postural alignment parameters (i.e: SVA plumbline between C7 and posterior corner of the sacrum; ODHA angle between line joining odontoid process and middle of hip axis with the vertical). Movement analysis was performed during walking, sit-to-stand, and stair ascent-descent with the calculation of 3D joint and segment kinematics. Participants filled out QOL questionnaires (SF-36 with both physical and mental components, Oswestry Disability Index ODI). The strength of the following muscle groups was measured using a hand-held dynamometer: trunk extensors, flexors, and right & left lateral flexors. ASD were divided into 2 groups based on the age-normalized strength of trunk extensors compared to controls: ASD-normal extensors and ASD-weak extensors (having strength<mean-1SD in controls). Radiographic parameters, kinematic variables, and QOL scores were compared between groups. 6 ASD had weak extensors (F=20 vs. 26 N in controls). The ASD-weak extensors patients showed a forward sagittal alignment compared to ASD-normal extensors in the standing position (ODHA=5 vs 3°, SVA =73 vs 24 mm). They had to increase their pelvic retroversion while sitting in order to maintain a horizontal gaze (sitting-pelvic tilt=41 vs 35° in ASD-normal extensors). The sagittal malalignment persisted during the different performed movements (dynamic-ODHA=16° vs 9° in ASD-normal extensors). However, ASD with normal extensors had less alterations in their radiographic and kinematic parameters. Muscle weakness was correlated to the deterioration of QOL (physical component-SF36: r=0.55; p<0.001) and decreased walking speed (r=0.44; p<0.001, Fig. 1). This pilot study showed that weak trunk extensors are associated with sagittal malalignment in standing and sitting positions, as well as during daily life activities. Weak extensors also correlate to deteriorated quality of life in ASD. Normal strength of trunk extensors seems to help ASD patients in compensating for their spinal deformity both in static and during movement. Future studies will investigate the effect of muscle strengthening on both static and dynamic","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Gait & posture
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1