Turk psikiyatri dergisi = Turkish journal of psychiatry最新文献

Objective: The caregiver burden in the relatives of patients with schizophrenia increases mental health problems in patients, complicates coping with the illness for families, and adversely affects the course of the illness. This study aims to investigate the effects of patients' psychopathology severity and cognitive functions on caregiver burden.

Method: Forty-four patients diagnosed with schizophrenia according to DSM-5 and their primary caregivers were included in this cross-sectional descriptive study. The severity of the caregiver burden in the relatives of the patients was evaluated using the Zarit Caregiver Burden Scale (ZCBS). Symptom severity of the patients was evaluated with the Scale for the Assessment of Positive Symptoms (SAPS) and the Scale for the Assessment of Negative Symptoms (SANS). Wisconsin Card Sorting Test (WCST), Stroop Test, Trail Making Test (TMT), and Rey Auditory Verbal Learning Test (RAVLT) were applied to assess the cognitive functions of the patients.

Results: The mean ZCBS score was 47.7±26.9 in the primary caregivers of the patients. There was a significant negative correlation between ZCBS and patients' education level, time since recent hospitalization, and RAVLT scores, and a significant positive correlation between TMT, Stroop Test, and SANS scores.

Conclusion: To reduce the caregiver burden, psychosocial interventions for cognitive dysfunction and negative symptoms involving patients and their families should be considered a priority.

Objective: The effects of antipsychotics on negative symptoms are limited. The most appropriate approach in the treatment of schizophrenia is the integration of drug therapy with psychological and social interventions. The purpose of this study was to evaluate and compare the effects of art therapy and psychosocial skills training (PSST) in the treatment of schizophrenia.

Methods: A total of 15 patients diagnosed with schizophrenia according to the criteria in DSM-5 and 12 patient relatives were included in the study. The patients were randomly divided into 2 groups, 7 were included in the art therapy program and 8 were included in the PSST program for schizophrenia. 90-minute sessions of art therapy and PSST were carried out once a week for 17 weeks. Participants with schizophrenia were evaluated with the Positive and Negative Syndrome Scale (PANSS), Social Functioning Scale (SFS) and the Calgary Depression Scale for Schizophrenia and the relatives were given Beck Depression Inventory, Beck Anxiety Inventory and Zarit Burden Interview.

Results: There was a significant decrease in the PANSS negative symptoms, PANSS general psychopathology, SFS pro-social activities and SFS recreation scores in both groups, while the SFS social withdrawal scores decreased significantly only in the art therapy group. In the PANSS negative symptoms subscale, passive social withdrawal, difficulty in abstract thinking, lack of spontaneity and flow of conversation and stereotyped thinking scores were significantly lower in the art therapy group. In the PSST group only the score for difficulty in abstract thinking declined significantly.

Conclusion: The findings of the present study suggest that art therapy and PSST have positive effects on the improvement of negative symptoms as well as improvements in social and cognitive functionality in schizophrenia.

Objective: This study aims to evaluate the severity of substance use disorders according to the DSM-5 criteria and to show the reliability and validity of the Turkish version of the DSM-5 Substance Use Scale that improved to learn what kind of substances are used.

Methods: In this study,54 in or out-patients who met the criteria for any substance use disorder according to DSM-5 and who are receiving treatment in Psychiatry Department of Celal Bayar University Faculty of Medicine and AMATEM department of Bakırköy Prof. Dr. Mahzar Osman Mental Health and Neurology Training and Research Hospital, were included. One hundred volunteers without any mental or physical disease were also recruited as the control group. Beside the DSM-5 Level 2 substance use scale, Addiction Profile İndex was used for concurrent validity. Internal consistency coefficient and item-total correlation analysis were performed for reliability analysis. ROC Analysis was used in the validity analysis.

Results: Mean age was 26.97±10.20 years in the study group and 39% of the sample (n=60) were female. 5.6% (n=3) of the patient group were female and 94.4% (n=51) were male. In the control group, 57% (n=57) were female and 43% (n=43) were male. Of the patients diagnosed with substance use disorder (n=54), 88.7% had opiate use disorder, 5.6% had polysubstance use disorder, 5.6% had other (unknown) substance (synthetic cannabinoid) use disorder and 1.8% of patients have cannabis use disorder. The internal consistency of the substance use scale was 0.80 and itemtotal correlation coefficients were between 0,196- 0,643 (p<0.0001). Coefficient of correlation analysis with API was calculated as r=0.806 (p<0.0001).

Conclusion: The results showed that DSM-5 Substance Use Scale is a valid and reliable questionnaire that can be used to measure the progress of different dimensions of alcohol and substance use.

Objective: Coronavirus Diseases-19 (COVID-19) pandemic that has caused the death of thousands of people affected negatively not only people's physical wellbeing but also their mental health. The aim of this study was to evaluate the sexual function, depression, anxiety and stress, and fear of COVID-19 of individuals according to gender and sexual orientation during the COVID-19 pandemic.

Method: The questionnaire form included sociodemographic data form, the Arizona Sexual Experiences Scale (ASEX), the Depression, Anxiety and Stress Scale-Short Form (DASS-21), and the Fear of COVID-19 Scale (FCV-19S). The form was distributed on social media platforms.

Results: 1593 sexually active participants were included in the study. 47.5% of the participants were females and 52.5% were males. 86.9% of them were heterosexuals and 13.1% were lesbian, gay, and bisexual (LGB) individuals. ASEX, DASS-21 Depression, Anxiety, and Stress, and FCV-19S scores were significantly higher in females than males (p<0.001). When anxiety, depression, stress, and fear of COVID-19 were controlled, level of sexual dysfunction continued to be higher in women. We found that while the ASEX and FCV-19S scores were similar between the heterosexuals and LGBs (respectively p=0.66 and p=0.31), the DASS-21 Depression, Anxiety, and Stress scores were higher in LGBs (p<0.001).

Conclusion: Our results reveal the effect of the pandemic period on female sexual functions and the importance of addressing this topic in clinical practice and research.

Objective: This study aims to determine the prevalence of depressive symptoms in the adult population in Türkiye and to examine the relationship of depression with socio-demographic and behavioral variables and chronic diseases.

Method: This sturdy utilized data from the 2019 Turkey Health Survey. The Patient Health Questionnaire Depression Module (PHQ- 8) was employed to assess depressive symptoms in the survey. Based on the analysis using the diagnostic algorithm of the PHQ-8, from a total of 17084 people aged 15+ years old who were, we selected 6.4% individuals with depressive symptoms. Then, we randomly selected 1101 individuals without depressive symptoms, comprising of a total of 2202 individuals as the study sample. We assessed the factors associated with depressive symptoms using multivariate logistic regression analyses.

Results: The risk of developing depressive symptoms increased with age. Women were more likely to report depressive symptoms. Education, physical activity, and marital status were negatively correlated with reporting depressive symptoms. Further, social support was a protective factor to report depressive symptoms. The presence of chronic diseases was positively associated with depressive symptoms.

Conclusion: The results showed that point and annual prevalence of depressive symptoms were high. The findings provide a basis for further studies to explore the factors associated with a higher prevalence of depressive symptoms in Türkiye. Our findings could serve as a reference to monitor depression in the country, as well as help in the planning of health resource and identify high risk segments of the population.

Objective: The aim of this study is to detect functional changes in the brain during the memory task with aging and the association between functional changes and memory performance.

Method: The study consisted of Young Adult Group (YAG, n=20) aged 20 to 25 and Late Adult Group (LAG, n=18) aged 60 to 70. Individuals with Montreal Cognitive Assessment (MoCA) scores above 21 and no family history of Alzheimer's Disease were included in the study. Functional Magnetic Resonance Imaging (fMRI) scanning was performed on all participants during a memory task including encoding (face and name), face and name recognition sub-tasks.

Results: Results indicated that LAG showed increased activity during face recognition task in left posterior cingulate cortex, left superior frontal cortex, left fusiform face area and another increased activity was found out during name recognition task in left superior frontal cortex, right prefrontal cortex, left anterior + posterior cingulate cortex. The accuracy of face recognition and name recognition memory tests were significantly lower in LAG (respectively, p=0.026; p=0.001).

Conclusion: These results indicated that advanced age were associated with more widespread activation in brain during memory task. Thus with aging, individuals require more neuronal and cognitive resources during memory processing.

Lithium may cause toxicity as it has a narrow therapeutic range. Lithium intoxication may manifest in the form of acute, acute on chronic and chronic intoxication. Neurotoxicity is a common component of chronic lithium intoxication and the symptoms include tremor, ataxia, dysarthria, extrapyramidal symptoms, hyperreflexia, seizures and status epilepticus. Although rare, catatonia could as a manifestation of lithium neurotoxicity. In this report, we present a patient with bipolar disorder presenting with catatonic symptoms secondary to lithium intoxication. We will discuss the risk factors, differential diagnosis and the treatment of catatonic symptoms. Lithium neurotoxicity may present with various clinical symptoms including catatonia, and differential diagnosis should be made well in such cases. If lithium neurotoxicity is suspected, rapid and appropriate intervention is required to prevent permanent neurological damage. Keywords: Lithium, Neurotoxicity, Catatonia.