Orhan Öztürk has created a "revolution" in Turkish psychiatry Needless to say, prominent figures were with him during this journey, Leyla Zileli, Doğan Karan and many others, but it was Orhan Bey who became the intellectual and organizational leader. This interview attempts to provide a critical and analytical perspective on Orhan Öztürk as a figure of central importance in the recent history of psychiatry. It aims to interpret and enrich historical knowledge while "placing Orhan Öztürk in history." In this interview conducted with Orhan Bey in January 2023, I focused on several topics, which is presented as subsections in the conversation.
{"title":"M. Orhan Öztürk Interview - Highlights.","authors":"Mehmet Sağman Kayatekin","doi":"10.5080/u27370","DOIUrl":"10.5080/u27370","url":null,"abstract":"<p><p>Orhan Öztürk has created a \"revolution\" in Turkish psychiatry Needless to say, prominent figures were with him during this journey, Leyla Zileli, Doğan Karan and many others, but it was Orhan Bey who became the intellectual and organizational leader. This interview attempts to provide a critical and analytical perspective on Orhan Öztürk as a figure of central importance in the recent history of psychiatry. It aims to interpret and enrich historical knowledge while \"placing Orhan Öztürk in history.\" In this interview conducted with Orhan Bey in January 2023, I focused on several topics, which is presented as subsections in the conversation.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"34 4","pages":"300-302"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10786357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139089832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The aim of this study was to evaluate the development of primary (PCs) and secondary capacities (SCs) in individuals diagnosed with antisocial personality disorder (ASPD) and the effects of these capacities on delinquent behaviors and anger levels.
Methods: 101 male patients aged 18 years and over with a diagnosis of ASPD were divided into two groups as those with a criminal ASPD (cASPD) diagnosis (n=37) and those with a non-criminal ASPD (ncASPD) diagnosis (n=64). Participants were evaluated using a sociodemographic form, Wiesbaden's Inventory of Positive Psychotherapy and Family Therapy (WIPPF-2) and State-Trait Anger Expression Inventory (STAXI). Statistical analyses were performed using the SPSS 22.0 program; significance level was taken as p0.05.
Results: PCs, SCs and anger control levels of people with ASPD were lower while trait anger, anger expression and anger import were higher than the control group. In cASPD, among the PCs, belief (β=0.796, p=0.032), hope (β=-1.069, p=0.011), relationship (β=-0.980, p=0.007) and sexuality (β=0.937, p=0.021) predicted anger-out, and among the SAs politeness (β=-1.020, p=0.002) and reliability (β=1.140, p=0.001) predicted trait anger level. In ncASPD, patience predicted anger-out (β=-1.752, p=0.001) and anger control (β=1.468, p=0.002); belief (β=1.468, p=0.005) and trust (β=-0.845, p=0.002) predicted anger control.
Conclusions: Positive psychotherapy can be effective in improving PCs and SCs of individuals with ASPD, improving interpersonal relationships, reducing criminal behaviors, anger management and psychotherapeutic treatment of ASPD.
{"title":"Primary and Secondary Capacities in the Context of Positive Psychotherapy in Individuals with Antisocial Personality Disorder: The Relationship with Criminal Behaviors and Anger.","authors":"Özgür Maden, Ebru Sinici, Özcan Uzun","doi":"10.5080/u27031","DOIUrl":"10.5080/u27031","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the development of primary (PCs) and secondary capacities (SCs) in individuals diagnosed with antisocial personality disorder (ASPD) and the effects of these capacities on delinquent behaviors and anger levels.</p><p><strong>Methods: </strong>101 male patients aged 18 years and over with a diagnosis of ASPD were divided into two groups as those with a criminal ASPD (cASPD) diagnosis (n=37) and those with a non-criminal ASPD (ncASPD) diagnosis (n=64). Participants were evaluated using a sociodemographic form, Wiesbaden's Inventory of Positive Psychotherapy and Family Therapy (WIPPF-2) and State-Trait Anger Expression Inventory (STAXI). Statistical analyses were performed using the SPSS 22.0 program; significance level was taken as p0.05.</p><p><strong>Results: </strong>PCs, SCs and anger control levels of people with ASPD were lower while trait anger, anger expression and anger import were higher than the control group. In cASPD, among the PCs, belief (β=0.796, p=0.032), hope (β=-1.069, p=0.011), relationship (β=-0.980, p=0.007) and sexuality (β=0.937, p=0.021) predicted anger-out, and among the SAs politeness (β=-1.020, p=0.002) and reliability (β=1.140, p=0.001) predicted trait anger level. In ncASPD, patience predicted anger-out (β=-1.752, p=0.001) and anger control (β=1.468, p=0.002); belief (β=1.468, p=0.005) and trust (β=-0.845, p=0.002) predicted anger control.</p><p><strong>Conclusions: </strong>Positive psychotherapy can be effective in improving PCs and SCs of individuals with ASPD, improving interpersonal relationships, reducing criminal behaviors, anger management and psychotherapeutic treatment of ASPD.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"34 3","pages":"191-201"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41159326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The aim of this study was to qualitatively examine Turkish tweets about schizophrenia in respect of stigmatization and discrimination within a one-month period and to conduct emotional analysis using artificial intelligence applications.
Method: Using the keyword 'schizophrenia,' Turkish tweets were gathered from the Python Tweepy application between December 19, 2020 and January 18, 2021. Features were extracted using the Bidirectional Encoder Representations from Transformers (BERT) method and artificial neural networks and tweets were classified as positive, neutral, or negative. Approximately 5% of the tweets were qualitatively analyzed, constituting those most frequently liked and retweeted.
Results: The study found that, of the total of 3406 schizophreniarelated messages shared in Turkey over a period of one-month, 2996 were original, and were then retweeted a total of 1823 times, and liked by 25,413 people. It was determined that 63.4% of the tweets shared about schizophrenia contained negative emotions, 28.7% were neutral, and 7.71% expressed positive emotions. Within the scope of the qualitative analysis, 145 tweets were examined and classified under four main themes and two sub-themes; namely, news about violent patients, insult (insulting people in interpersonal relationships, insulting people in the news), mockery, and information.
Conclusion: The results of this study showed that the Turkish tweets about schizophrenia, which were emotionally analyzed using artificial intelligence were found often to contain negative emotions. It was also seen that Twitter users used the term schizophrenia, not in a medical sense but to insult and make fun of individuals, frequently shared the news that patients were victims or perpetrators of violence, and the messages shared by professional branch organizations or mental health professionals were primarily for conveying information to the public.
{"title":"Qualitative and Artificial Intelligence-Based Sentiment Analysis of Turkish Tweets Related to Schizophrenia.","authors":"Gül Dikeç, Volkan Oban, Miraç Barış Usta","doi":"10.5080/u26402","DOIUrl":"10.5080/u26402","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to qualitatively examine Turkish tweets about schizophrenia in respect of stigmatization and discrimination within a one-month period and to conduct emotional analysis using artificial intelligence applications.</p><p><strong>Method: </strong>Using the keyword 'schizophrenia,' Turkish tweets were gathered from the Python Tweepy application between December 19, 2020 and January 18, 2021. Features were extracted using the Bidirectional Encoder Representations from Transformers (BERT) method and artificial neural networks and tweets were classified as positive, neutral, or negative. Approximately 5% of the tweets were qualitatively analyzed, constituting those most frequently liked and retweeted.</p><p><strong>Results: </strong>The study found that, of the total of 3406 schizophreniarelated messages shared in Turkey over a period of one-month, 2996 were original, and were then retweeted a total of 1823 times, and liked by 25,413 people. It was determined that 63.4% of the tweets shared about schizophrenia contained negative emotions, 28.7% were neutral, and 7.71% expressed positive emotions. Within the scope of the qualitative analysis, 145 tweets were examined and classified under four main themes and two sub-themes; namely, news about violent patients, insult (insulting people in interpersonal relationships, insulting people in the news), mockery, and information.</p><p><strong>Conclusion: </strong>The results of this study showed that the Turkish tweets about schizophrenia, which were emotionally analyzed using artificial intelligence were found often to contain negative emotions. It was also seen that Twitter users used the term schizophrenia, not in a medical sense but to insult and make fun of individuals, frequently shared the news that patients were victims or perpetrators of violence, and the messages shared by professional branch organizations or mental health professionals were primarily for conveying information to the public.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"34 3","pages":"145-153"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645022/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41172858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this review, we aimed to outline the scientific advances and service capacity in Turkish psychiatry within the century-long history of the Republic. We propose that the history of Turkish Psychiatry also sheds light on the history of our country. We have reviewed significant milestones in Turkish Psychiatry; the establishment of psychiatric hospitals, the development of formal psychiatry training, academic and scientific proceedings and the founding of professional organizations in the Republic era. We aimed to offer insights into the role of psychiatry in the modernization of our country, as well as to establish a foundation for future improvements by evaluating the progress made in the field of mental health services. The story that began with 20 neuropsychiatrists and 300 psychiatric beds in one mental hospital has now reached over 4000 psychiatrists and twenty-thousand psychiatric beds. Psychiatry in Türkiye continues its historical evolution with expansion in size and advancements in quality. Keywords: History of Psychiatry in Türkiye, History of the Republic of Türkiye, History of Medicine.
{"title":"A Brief History of Psychiatry in the 100th Anniversary of the Republic of Türkiye.","authors":"Kazım Cihan Can, Tarık Tuna Gözütok, Şahap Erkoç","doi":"10.5080/u27437","DOIUrl":"10.5080/u27437","url":null,"abstract":"<p><p>In this review, we aimed to outline the scientific advances and service capacity in Turkish psychiatry within the century-long history of the Republic. We propose that the history of Turkish Psychiatry also sheds light on the history of our country. We have reviewed significant milestones in Turkish Psychiatry; the establishment of psychiatric hospitals, the development of formal psychiatry training, academic and scientific proceedings and the founding of professional organizations in the Republic era. We aimed to offer insights into the role of psychiatry in the modernization of our country, as well as to establish a foundation for future improvements by evaluating the progress made in the field of mental health services. The story that began with 20 neuropsychiatrists and 300 psychiatric beds in one mental hospital has now reached over 4000 psychiatrists and twenty-thousand psychiatric beds. Psychiatry in Türkiye continues its historical evolution with expansion in size and advancements in quality. Keywords: History of Psychiatry in Türkiye, History of the Republic of Türkiye, History of Medicine.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"34 4","pages":"282-287"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10786352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139089819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Great Teacher: M. Orhan Öztürk.","authors":"Aylin Uluşahin","doi":"10.5080/u27441","DOIUrl":"10.5080/u27441","url":null,"abstract":"","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"34 4","pages":"221-222"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10786355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139089830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pandemics are social events that affect individuals' lives in many ways and have a significant impact on the mental health of masses. Pandemics and measures taken to combat these epidemics affect children and young people as well as adults. The purpose of the current review is to compile studies that have been conducted on the psychological effects of the COVID-19 pandemic and related measures on children, youth, and parents, and use the findings to shed light on future studies. In this review, 35 studies that were determined as a result of a comprehensive search in relevant literature were examined. It was observed that the aforementioned studies noted that the COVID-19 global pandemic and the measures taken to combat the epidemic (e.g., quarantine, lockdown, and school closures) had negative psychological effects on children, young people, and parents. Problems observed in children and young people, such as the fear of catching or transmitting the virus, getting bored, not being able to communicate enough with friends and teachers, and problems observed in parents, such as the troubles of negative repercussions of working at home or unemployment and difficulties in communicating with children with the closure of schools, are only a few to name these negative effects. The reviewed studies were discussed taking their limitations into account. Recommendations were made for future studies and intervention programs to be planned for community mental health. Keywords: COVID-19, children and youth, parents, pandemic, quarantine.
{"title":"A Review of Studies on the Covid-19 Pandemic and the Psychological Effects of Related Measures on Children, Youth and Parents.","authors":"Burcu Altin, Gülsen Erden","doi":"10.5080/u25936","DOIUrl":"10.5080/u25936","url":null,"abstract":"<p><p>Pandemics are social events that affect individuals' lives in many ways and have a significant impact on the mental health of masses. Pandemics and measures taken to combat these epidemics affect children and young people as well as adults. The purpose of the current review is to compile studies that have been conducted on the psychological effects of the COVID-19 pandemic and related measures on children, youth, and parents, and use the findings to shed light on future studies. In this review, 35 studies that were determined as a result of a comprehensive search in relevant literature were examined. It was observed that the aforementioned studies noted that the COVID-19 global pandemic and the measures taken to combat the epidemic (e.g., quarantine, lockdown, and school closures) had negative psychological effects on children, young people, and parents. Problems observed in children and young people, such as the fear of catching or transmitting the virus, getting bored, not being able to communicate enough with friends and teachers, and problems observed in parents, such as the troubles of negative repercussions of working at home or unemployment and difficulties in communicating with children with the closure of schools, are only a few to name these negative effects. The reviewed studies were discussed taking their limitations into account. Recommendations were made for future studies and intervention programs to be planned for community mental health. Keywords: COVID-19, children and youth, parents, pandemic, quarantine.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"34 3","pages":"202-214"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41168808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clean Words Come Out of Clean Minds","authors":"Yavuz Ayhan","doi":"10.5080/u27408","DOIUrl":"10.5080/u27408","url":null,"abstract":"<p><p>No abstract available.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"34 3","pages":"143-144"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645018/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41168170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The aim of the study was to evaluate stigmatizing attitudes towards schizophrenia among Turkish Twitter users.
Methods: In the study designed with the qualitative research method, the tweets containing the keywords "schizophrenia", "schizophrenic", "psychotic" and "psychosis" in Turkish on Twitter were collected using the Knime program. The main themes and sub-themes were created by content analysis.
Results: The studies revealed three major themes: "insult", "negative point of view", and "anti-stigma". While the sub-themes of "swearing" and "mocking" were determined under the main theme of "insult", the sub-theme of "false beliefs" was determined under the theme of "negative point of view", and the sub-themes of "medically appropriate" and "defensive" were determined under the main theme of "antistigma". In the results, it was determined that the word schizophrenia was commonly used to humiliate others and used as a way of addressing with slang words or to mock and that there were stigmatizing statements revealing negative feelings and thoughts in such a way that they would be inconsistent with medical information.
Conclusion: The results of this study can be used to develop programs to combat stigma against schizophrenia disorder and to determine content.
{"title":"Using Twitter to Assess Stigma to Schizophrenia and Psychosis: A Qualitative Study.","authors":"Kerime Bademli, Ayten Kaya Kiliç, Mehmet Kayakuş","doi":"10.5080/u27280","DOIUrl":"10.5080/u27280","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to evaluate stigmatizing attitudes towards schizophrenia among Turkish Twitter users.</p><p><strong>Methods: </strong>In the study designed with the qualitative research method, the tweets containing the keywords \"schizophrenia\", \"schizophrenic\", \"psychotic\" and \"psychosis\" in Turkish on Twitter were collected using the Knime program. The main themes and sub-themes were created by content analysis.</p><p><strong>Results: </strong>The studies revealed three major themes: \"insult\", \"negative point of view\", and \"anti-stigma\". While the sub-themes of \"swearing\" and \"mocking\" were determined under the main theme of \"insult\", the sub-theme of \"false beliefs\" was determined under the theme of \"negative point of view\", and the sub-themes of \"medically appropriate\" and \"defensive\" were determined under the main theme of \"antistigma\". In the results, it was determined that the word schizophrenia was commonly used to humiliate others and used as a way of addressing with slang words or to mock and that there were stigmatizing statements revealing negative feelings and thoughts in such a way that they would be inconsistent with medical information.</p><p><strong>Conclusion: </strong>The results of this study can be used to develop programs to combat stigma against schizophrenia disorder and to determine content.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"34 3","pages":"154-161"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10645016/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41170171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Mart, Feride Figen Ateşci, M. Mart, Mücahit Seçme, Y. Dodurga, B. Albuz
OBJECTIVE The aim of this study was to determine DNA damage during euthymic and attack periods, and the oxidative metabolism states that may cause this damage in the pathophysiology of bipolar disorder. The role of DNA repair mechanisms in this process was also investigated. METHOD The study included a total of 90 patients aged between 18-65 years who were diagnosed with bipolar disorder according to DSM- 5 diagnostic criteria, with 30 patients in euthymic, 30 in manic and 30 in depressive periods. A control group was formed of 30 healthy subjects matched to the patients by age, gender, body mass index and smoking status and/or alcohol consumption. Oxidative metabolism was investigated using the Comet Assay technique to assess DNA damage, according to the oxidant/antioxidant status in the technique developed by Erel with the Rel ASSAY Diagnostics kit (Turkey). The control and patient groups were compared in respect of gene expression levels of OGG1 and NEIL1 repair genes at mRNA level with Real-Time PCR. RESULTS Increased DNA damage was found in the euthymic and manic groups and decreased NEIL1 gene expression in the depressive group. The oxidative stress index was found to be decreased in the patient groups compared to the healthy control group. CONCLUSION Oxidative imbalance and DNA damage and repair disorders may be effective in the pathophysiology of bipolar disorder. Further studies on this subject are required to clarify the etiology and new treatment goals.
{"title":"Analysis of Differences in DNA Damage and Repair Efficacy in Lymphocytes of Patients with Bipolar Disorder.","authors":"G. Mart, Feride Figen Ateşci, M. Mart, Mücahit Seçme, Y. Dodurga, B. Albuz","doi":"10.5080/u26116","DOIUrl":"https://doi.org/10.5080/u26116","url":null,"abstract":"OBJECTIVE The aim of this study was to determine DNA damage during euthymic and attack periods, and the oxidative metabolism states that may cause this damage in the pathophysiology of bipolar disorder. The role of DNA repair mechanisms in this process was also investigated. METHOD The study included a total of 90 patients aged between 18-65 years who were diagnosed with bipolar disorder according to DSM- 5 diagnostic criteria, with 30 patients in euthymic, 30 in manic and 30 in depressive periods. A control group was formed of 30 healthy subjects matched to the patients by age, gender, body mass index and smoking status and/or alcohol consumption. Oxidative metabolism was investigated using the Comet Assay technique to assess DNA damage, according to the oxidant/antioxidant status in the technique developed by Erel with the Rel ASSAY Diagnostics kit (Turkey). The control and patient groups were compared in respect of gene expression levels of OGG1 and NEIL1 repair genes at mRNA level with Real-Time PCR. RESULTS Increased DNA damage was found in the euthymic and manic groups and decreased NEIL1 gene expression in the depressive group. The oxidative stress index was found to be decreased in the patient groups compared to the healthy control group. CONCLUSION Oxidative imbalance and DNA damage and repair disorders may be effective in the pathophysiology of bipolar disorder. Further studies on this subject are required to clarify the etiology and new treatment goals.","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"42 1","pages":"158-166"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86001641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OBJECTIVE The aim of this research was to assess gaze behaviors and facial affect expressions in mother-infant interaction within the frame of self-contingency and interactive contingency, reflecting self-regulation and interactive regulation, respectively. In Model 1, second-by-second changing gaze behaviors (on partner's face/off partner's face) and in Model 2, facial affect expressions (from positive to negative) were examined. Self-contingency reflects the variability or stability in gaze directions and facial affect expressions in each partner. Interactive contingency reflects the degree of mother-infant gaze and facial affect attunement or interactive regulation relative to each other. METHOD Sample was composed of 56 healthy mother-infant dyads. All infants were 4 months old, and mean maternal age was 29.61 (SD=3.71). Mother-infant interactions were filmed at the lab. Interactions were coded second-by-second for mother-infant gaze behaviors and facial affect expressions with video microanalysis method. The analysis method was multilevel-multivariate time series analysis. RESULTS According to Model 1-2, mother-infant gaze behaviors and facial affect expressions were neither too stable nor too variable, rather, the change in gaze behaviors and facial affect expressions in each partner showed predictable patterns. Mothers regulated their gaze behaviors and facial affect expressions in relation to that of their infants. Infants regulated their facial affect expressions in relation to their mothers' facial affect expressions, but infant gaze interactive contingency to mother gaze was marginally significant. CONCLUSION In interactions, infants and mothers regulate the rhythms of their own behavior and at the same time contingently coordinate with that of the partner. This bi-directionally regulating environment is the foundation of infants' relationship expectations and bio-socialbehavioral regulation capacity, which may be related to psychopathology in future.
{"title":"The Bidirectional View of Mother-Infant Interaction by Gaze and Facial Affect.","authors":"Yasemin Kahya, S. Uluç, Yusuf Kara","doi":"10.5080/u25794","DOIUrl":"https://doi.org/10.5080/u25794","url":null,"abstract":"OBJECTIVE The aim of this research was to assess gaze behaviors and facial affect expressions in mother-infant interaction within the frame of self-contingency and interactive contingency, reflecting self-regulation and interactive regulation, respectively. In Model 1, second-by-second changing gaze behaviors (on partner's face/off partner's face) and in Model 2, facial affect expressions (from positive to negative) were examined. Self-contingency reflects the variability or stability in gaze directions and facial affect expressions in each partner. Interactive contingency reflects the degree of mother-infant gaze and facial affect attunement or interactive regulation relative to each other. METHOD Sample was composed of 56 healthy mother-infant dyads. All infants were 4 months old, and mean maternal age was 29.61 (SD=3.71). Mother-infant interactions were filmed at the lab. Interactions were coded second-by-second for mother-infant gaze behaviors and facial affect expressions with video microanalysis method. The analysis method was multilevel-multivariate time series analysis. RESULTS According to Model 1-2, mother-infant gaze behaviors and facial affect expressions were neither too stable nor too variable, rather, the change in gaze behaviors and facial affect expressions in each partner showed predictable patterns. Mothers regulated their gaze behaviors and facial affect expressions in relation to that of their infants. Infants regulated their facial affect expressions in relation to their mothers' facial affect expressions, but infant gaze interactive contingency to mother gaze was marginally significant. CONCLUSION In interactions, infants and mothers regulate the rhythms of their own behavior and at the same time contingently coordinate with that of the partner. This bi-directionally regulating environment is the foundation of infants' relationship expectations and bio-socialbehavioral regulation capacity, which may be related to psychopathology in future.","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"11 1","pages":"32-43"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75538420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}