Pub Date : 2024-07-04DOI: 10.1016/j.oor.2024.100594
Gokul Sudhakaran
{"title":"Letter to editor: Comment on “Quantitative and qualitative features of tissue biopsy for successful diagnosis of oral cancer”","authors":"Gokul Sudhakaran","doi":"10.1016/j.oor.2024.100594","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100594","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"11 ","pages":"Article 100594"},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004400/pdfft?md5=db38472d6824e8563de24cc0791af2be&pid=1-s2.0-S2772906024004400-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-04DOI: 10.1016/j.oor.2024.100597
Gokul Sudhakaran
{"title":"Letter to editor: Comment on “identification of a potential prognostic panel of biomarkers for stratification of head and neck squamous cell carcinoma based on HPV status and TP53 mutational status”","authors":"Gokul Sudhakaran","doi":"10.1016/j.oor.2024.100597","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100597","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"11 ","pages":"Article 100597"},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004436/pdfft?md5=00948d5968e74df03eb9704a3e945b21&pid=1-s2.0-S2772906024004436-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-04DOI: 10.1016/j.oor.2024.100580
Amol S. Dhane
{"title":"Financial toxicity in head and neck cancer care: Current issues and future directions","authors":"Amol S. Dhane","doi":"10.1016/j.oor.2024.100580","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100580","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"11 ","pages":"Article 100580"},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004266/pdfft?md5=40fa213f5ef8c11a9696fc654db0efed&pid=1-s2.0-S2772906024004266-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-04DOI: 10.1016/j.oor.2024.100587
Baishakhi Modak (Final year postgraduate), Spoorti Kulkarni (Associate professor)
Aims
This review article aims to provide an in-depth analysis of potentially malignant and malignant verrucopapillary lesions, including their etiology, clinical and histological features, differential diagnosis, and immunohistochemical analysis.
Background
The word verrucopapillary lesions (VPL) refers to a variety of lesions in the oral region, ranging from benign to completely malignant tumors. They cause surface changes that can be seen as ulcerative, vesiculobullous, or papillary/papular/polypoid lesions, altering the usual morphology and stability of the mucosa.
Review results
The clinical, histopathological and immunohistochemical characteristics of oral verrucopapillary lesions may help in their accurate diagnosis.
Clinical significance
Verrucous and papillary lesions of the oral cavity are diagnostically challenging because of similar clinical presentation. The current understanding of potentially malignant VPLs is perplexing due to numerous terminologies. Many of the controversies in these entities are due to the lack of consensus on the disease characteristics and management.
{"title":"Clinicopathological analysis of potentially malignant and malignant verrucopapillary lesions of the oral cavity – A literature review","authors":"Baishakhi Modak (Final year postgraduate), Spoorti Kulkarni (Associate professor)","doi":"10.1016/j.oor.2024.100587","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100587","url":null,"abstract":"<div><h3>Aims</h3><p>This review article aims to provide an in-depth analysis of potentially malignant and malignant verrucopapillary lesions, including their etiology, clinical and histological features, differential diagnosis, and immunohistochemical analysis.</p></div><div><h3>Background</h3><p>The word verrucopapillary lesions (VPL) refers to a variety of lesions in the oral region, ranging from benign to completely malignant tumors. They cause surface changes that can be seen as ulcerative, vesiculobullous, or papillary/papular/polypoid lesions, altering the usual morphology and stability of the mucosa.</p></div><div><h3>Review results</h3><p>The clinical, histopathological and immunohistochemical characteristics of oral verrucopapillary lesions may help in their accurate diagnosis.</p></div><div><h3>Clinical significance</h3><p>Verrucous and papillary lesions of the oral cavity are diagnostically challenging because of similar clinical presentation. The current understanding of potentially malignant VPLs is perplexing due to numerous terminologies. Many of the controversies in these entities are due to the lack of consensus on the disease characteristics and management.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"11 ","pages":"Article 100587"},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004333/pdfft?md5=0ff2fa02af82b57f79282696ac752549&pid=1-s2.0-S2772906024004333-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141607661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-04DOI: 10.1016/j.oor.2024.100570
Madhan Krishnan, Shyamaladevi Babu
{"title":"Advancements in immunotherapy: Transforming the landscape of oral cancer treatment","authors":"Madhan Krishnan, Shyamaladevi Babu","doi":"10.1016/j.oor.2024.100570","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100570","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"11 ","pages":"Article 100570"},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004163/pdfft?md5=f13cba48706a92ea29655bf20cc935f4&pid=1-s2.0-S2772906024004163-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-04DOI: 10.1016/j.oor.2024.100581
Geetha Shanmugam
{"title":"Letter to the editor, “Inhibition of anti-tumour reactivity of immune cells in the salivary gland cancer: A proteomic approach.”","authors":"Geetha Shanmugam","doi":"10.1016/j.oor.2024.100581","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100581","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"11 ","pages":"Article 100581"},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004278/pdfft?md5=19c7346fe011d78a1961b53a0ca4b1c7&pid=1-s2.0-S2772906024004278-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The glandular odontogenic cyst is a rare developmental cyst with odontogenic origins that shares similarities with other odontogenic lesions. While generally considered benign, GOCs can exhibit aggressive behavior and may transform into more aggressive lesions like ameloblastoma or mucoepidermoid carcinoma. Therefore, it is crucial to closely monitor and follow up after treatment. With less than 200 reported cases in the literature, GOCs are important due to their propensity for recurrence and potential confusion with other lesions. Oral and maxillofacial radiologists play a key role in diagnosing GOC, given its complex histopathology. In this particular case, a 14-year-old male presented with a well-defined radiolucent lesion in his posterior mandibular ramus, making it the third reported case of GOC in Syria. The discovery of the lesion was incidental, as it was found during a routine panoramic view. The radiolucent lesion extended from the distal border and apex of the lower right first premolar into the ramus, indicating the need for thorough diagnostic evaluation and proper management of the condition. This case report emphasizes the importance of recognizing and addressing such lesions early on to prevent any potential complications. As GOCs can be locally aggressive and have a tendency to recur, timely diagnosis and appropriate treatment are crucial in ensuring the best possible outcome for the patient. Further studies and research are needed to better understand the characteristics and behavior of GOCs in the mandibular ramus region.
{"title":"Rare case of glandular odontogenic cyst in the posterior mandibular ramus: A case report","authors":"Nasem Jamal Yousef, Issa Saad, Marwan Al-Raeei, Chadi Azmeh, Maya Saad, Zeina Darwich, Maya Jokhadar, Ammar Nasser Agha, Waad Omran, Thayer Marouf","doi":"10.1016/j.oor.2024.100586","DOIUrl":"10.1016/j.oor.2024.100586","url":null,"abstract":"<div><p>The glandular odontogenic cyst is a rare developmental cyst with odontogenic origins that shares similarities with other odontogenic lesions. While generally considered benign, GOCs can exhibit aggressive behavior and may transform into more aggressive lesions like ameloblastoma or mucoepidermoid carcinoma. Therefore, it is crucial to closely monitor and follow up after treatment. With less than 200 reported cases in the literature, GOCs are important due to their propensity for recurrence and potential confusion with other lesions. Oral and maxillofacial radiologists play a key role in diagnosing GOC, given its complex histopathology. In this particular case, a 14-year-old male presented with a well-defined radiolucent lesion in his posterior mandibular ramus, making it the third reported case of GOC in Syria. The discovery of the lesion was incidental, as it was found during a routine panoramic view. The radiolucent lesion extended from the distal border and apex of the lower right first premolar into the ramus, indicating the need for thorough diagnostic evaluation and proper management of the condition. This case report emphasizes the importance of recognizing and addressing such lesions early on to prevent any potential complications. As GOCs can be locally aggressive and have a tendency to recur, timely diagnosis and appropriate treatment are crucial in ensuring the best possible outcome for the patient. Further studies and research are needed to better understand the characteristics and behavior of GOCs in the mandibular ramus region.</p></div>","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"11 ","pages":"Article 100586"},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004321/pdfft?md5=b4ee69158513ddae47d08f44daa9e24c&pid=1-s2.0-S2772906024004321-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141715687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-03DOI: 10.1016/j.oor.2024.100576
Akankshya Dash, Chinnasamy Ragavendran
{"title":"Evaluating ddPCR and RT-qPCR methods for PIK3CA mutation detection in head and neck cancer via precision oncology","authors":"Akankshya Dash, Chinnasamy Ragavendran","doi":"10.1016/j.oor.2024.100576","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100576","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"11 ","pages":"Article 100576"},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004229/pdfft?md5=4aefa481760bbcb497e16ec4d877173a&pid=1-s2.0-S2772906024004229-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-03DOI: 10.1016/j.oor.2024.100577
Muthupandian Saravanan
{"title":"Comment on “Salivary exosomes as potential biomarkers in cancer”","authors":"Muthupandian Saravanan","doi":"10.1016/j.oor.2024.100577","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100577","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"11 ","pages":"Article 100577"},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004230/pdfft?md5=f317c69d52343e34c64adf002c63bc30&pid=1-s2.0-S2772906024004230-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-03DOI: 10.1016/j.oor.2024.100595
Gokul Sudhakaran
{"title":"Letter to editor: Comment on “multi-omics approach reveals promising salivary protein markers for head and neck squamous cell carcinoma prognosis\"","authors":"Gokul Sudhakaran","doi":"10.1016/j.oor.2024.100595","DOIUrl":"https://doi.org/10.1016/j.oor.2024.100595","url":null,"abstract":"","PeriodicalId":94378,"journal":{"name":"Oral Oncology Reports","volume":"11 ","pages":"Article 100595"},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772906024004412/pdfft?md5=740753f7f79641d42b1cd07fe83cac30&pid=1-s2.0-S2772906024004412-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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