Pub Date : 2023-10-23DOI: 10.1021/cen-10135-buscon1
None Matt Blois
Over the past decade, a number of companies have tried and failed to commercialize biobased production of acrylic acid , a monomer used to make paints, coatings, and superabsorbent polymers for diapers. Despite those false starts, two projects are moving ahead for biobased acrylic acid or its precursors. LG Chem and GS Caltex hope to start up a demonstration plant in South Korea early next year that will produce biobased 3-hydroxypropionic acid (3-HP), which can be dehydrated into acrylic acid. The plant will use LG Chem’s fermentation process and separation technology from GS Caltex. 3-HP can also be used to make biodegradable plastics, the companies say. In 2019, LG Chem announced a partnership with ADM to make acrylic acid from corn. LG Chem says the partnership with GS Caltex is separate and will use a different technology. Meanwhile, Låkril Technologies, a start-up that spun out of Paul Dauenhauer’s University of
在过去的十年里，许多公司都试图将丙烯酸的生物基生产商业化，但都以失败告终。丙烯酸是一种用于制造油漆、涂料和尿布用高吸水性聚合物的单体。尽管有这些错误的开始，两个项目正在推进生物基丙烯酸或其前体。LG化学和GS Caltex计划在明年初在韩国建立生产脱水后可制成丙烯酸的生物基3-羟基丙酸(3-HP)的示范工厂。该工厂将采用LG化学的发酵工艺和GS Caltex的分离技术，3-HP还可以用于生产生物可降解塑料。2019年，LG化学宣布与ADM合作，从玉米中生产丙烯酸。LG化学表示，与GS Caltex的合作是独立的，将使用不同的技术。与此同时，从保罗·道恩豪尔(Paul daenhauer)的芝加哥大学(University of University)剥离出来的初创企业l kril技术公司(l kril Technologies)
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Pub Date : 2023-10-23DOI: 10.1021/cen-10135-buscon18
BUSINESS Business Roundup ShareShare onFacebookTwitterWechatLinked InRedditEmail C&EN, 2023, 101 (35), p 11October 23, 2023Cite this:C&EN 101, 35, 11AbstractLyondellBasell Industries has acquired a 50% interest in the Dutch plastics recycler De Paauw Sustainable Resources. De Paauw operates plants in Hengelo and Enschede, the Netherlands, and recycles mostly polypropylene and low-density polyethylene. CJ CheilJedang has signed an agreement to supply amino and organic acids to Lygos to make its Soltellus and Ecoteria products. Soltellus are biodegradable polymers used in water treatment and other applications, while Ecoteria is a family of malonates. Methanex is restarting a methanol plant with 875,000 metric tons (t) of annual capacity in Trinidad and Tobago in September 2024. That same month, it will idle a methanol plant in the country with 1.1 million t of output when a natural gas supply contract expires. Resonac is discontinuing its hard drive media business in Taiwan because of what it calls stagnant demand for hard drives. The Japanese chemical firm says it will liquidate the relevantView: PDF | Full Text HTMLDownload PDF
{"title":"Business Roundup","authors":"","doi":"10.1021/cen-10135-buscon18","DOIUrl":"https://doi.org/10.1021/cen-10135-buscon18","url":null,"abstract":"BUSINESS Business Roundup ShareShare onFacebookTwitterWechatLinked InRedditEmail C&EN, 2023, 101 (35), p 11October 23, 2023Cite this:C&EN 101, 35, 11AbstractLyondellBasell Industries has acquired a 50% interest in the Dutch plastics recycler De Paauw Sustainable Resources. De Paauw operates plants in Hengelo and Enschede, the Netherlands, and recycles mostly polypropylene and low-density polyethylene. CJ CheilJedang has signed an agreement to supply amino and organic acids to Lygos to make its Soltellus and Ecoteria products. Soltellus are biodegradable polymers used in water treatment and other applications, while Ecoteria is a family of malonates. Methanex is restarting a methanol plant with 875,000 metric tons (t) of annual capacity in Trinidad and Tobago in September 2024. That same month, it will idle a methanol plant in the country with 1.1 million t of output when a natural gas supply contract expires. Resonac is discontinuing its hard drive media business in Taiwan because of what it calls stagnant demand for hard drives. The Japanese chemical firm says it will liquidate the relevantView: PDF | Full Text HTMLDownload PDF","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"17 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135367261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1021/cen-10135-classifieds
{"title":"Classifieds","authors":"","doi":"10.1021/cen-10135-classifieds","DOIUrl":"https://doi.org/10.1021/cen-10135-classifieds","url":null,"abstract":"","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"347 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135366835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1021/cen-10135-scicon1
None Priyanka Runwal
In 2001, more than 90 nations signed a treaty to reduce or possibly eliminate the production and use of the so-called dirty dozen highly toxic chemicals that accumulate in the environment. These include pesticides such as DDT and chlordane and industrial compounds such as polychlorinated biphenyls (PCB). All these chemicals take decades to break down, get passed along the food chain, and are hazardous to humans and animals. Over the years, at least a dozen more persistent organic pollutants have been added to the treaty’s list . Orcas, also known as killer whales, are among the most affected marine animals . A recent study led by McGill University researchers found that the North Atlantic Ocean orcas they studied that mostly ate fish were less contaminated than orcas that preyed on marine mammals such as seals and dolphins ( Environ. Sci. Technol. 2023, DOI: 10.1021/acs.est.3c05516 ). In the Canadian Arctic Ocean,
{"title":"Diet determines orcas’ pollution exposure","authors":"None Priyanka Runwal","doi":"10.1021/cen-10135-scicon1","DOIUrl":"https://doi.org/10.1021/cen-10135-scicon1","url":null,"abstract":"In 2001, more than 90 nations signed a treaty to reduce or possibly eliminate the production and use of the so-called dirty dozen highly toxic chemicals that accumulate in the environment. These include pesticides such as DDT and chlordane and industrial compounds such as polychlorinated biphenyls (PCB). All these chemicals take decades to break down, get passed along the food chain, and are hazardous to humans and animals. Over the years, at least a dozen more persistent organic pollutants have been added to the treaty’s list . Orcas, also known as killer whales, are among the most affected marine animals . A recent study led by McGill University researchers found that the North Atlantic Ocean orcas they studied that mostly ate fish were less contaminated than orcas that preyed on marine mammals such as seals and dolphins ( Environ. Sci. Technol. 2023, DOI: 10.1021/acs.est.3c05516 ). In the Canadian Arctic Ocean,","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"12 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135366838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1021/cen-10135-leadcon
None Craig Bettenhausen
The Biden administration has selected seven projects for funding in the US Department of Energy’s Regional Clean Hydrogen Hubs program. The recipients, which are spread across the US, will each receive about $1 billion in federal money. When all seven projects are operating, they will produce 3 million metric tons (t) per year of low-carbon hydrogen and eliminate 25 million t of carbon dioxide emissions, the DOE says. At an event in Philadelphia announcing the funding choices, US president Joe Biden called climate change an existential threat to humanity and highlighted hydrogen’s ability to replace fossil fuels in heavy industries like chemical production . “When it comes to charging our cars or powering our homes, all we need is clean electricity . . . And we’re getting close to meeting that goal,” Biden said. “But when it comes to manufacturing things like steel, aluminum, and other materials, factories need to
{"title":"US to put $7 billion into H2 hubs","authors":"None Craig Bettenhausen","doi":"10.1021/cen-10135-leadcon","DOIUrl":"https://doi.org/10.1021/cen-10135-leadcon","url":null,"abstract":"The Biden administration has selected seven projects for funding in the US Department of Energy’s Regional Clean Hydrogen Hubs program. The recipients, which are spread across the US, will each receive about $1 billion in federal money. When all seven projects are operating, they will produce 3 million metric tons (t) per year of low-carbon hydrogen and eliminate 25 million t of carbon dioxide emissions, the DOE says. At an event in Philadelphia announcing the funding choices, US president Joe Biden called climate change an existential threat to humanity and highlighted hydrogen’s ability to replace fossil fuels in heavy industries like chemical production . “When it comes to charging our cars or powering our homes, all we need is clean electricity . . . And we’re getting close to meeting that goal,” Biden said. “But when it comes to manufacturing things like steel, aluminum, and other materials, factories need to","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"50 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135366964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1021/cen-10135-buscon16
None Laura Howes
Gilead Sciences is paying Assembly Biosciences $100 million for first refusal on all Assembly’s programs. The deal comprises $84.8 million in cash, plus $15.2 million in equity investment. Rather than buying the antiviral R&D firm outright, Gilead will integrate the company’s expertise in the herpes virus and hepatitis B and D. Assembly Bio will be responsible for early-stage research and development; if Gilead opts into any programs, it will take on all further work.
{"title":"Gilead to partner with Assembly Bio","authors":"None Laura Howes","doi":"10.1021/cen-10135-buscon16","DOIUrl":"https://doi.org/10.1021/cen-10135-buscon16","url":null,"abstract":"Gilead Sciences is paying Assembly Biosciences $100 million for first refusal on all Assembly’s programs. The deal comprises $84.8 million in cash, plus $15.2 million in equity investment. Rather than buying the antiviral R&D firm outright, Gilead will integrate the company’s expertise in the herpes virus and hepatitis B and D. Assembly Bio will be responsible for early-stage research and development; if Gilead opts into any programs, it will take on all further work.","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135367258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1021/cen-10135-buscon9
None Alex Tullo
The high-throughput experimentation company HTE is working with Stanford University chemistry professor Matthew Kanan on catalysts that make carbon monoxide from carbon dioxide. Metal-free reverse water-gas shift catalysts were tested for 3 months in HTE’s high-throughput units to get results that would have taken many years to obtain in his own lab, Kanan says . The ultimate hope is to be able to make chemicals and fuels from CO 2 emissions and hydrogen. Kanan says the performance of the catalysts has been encouraging for future scale-up.
{"title":"HTE working with Stanford on CO<sub>2</sub> to CO","authors":"None Alex Tullo","doi":"10.1021/cen-10135-buscon9","DOIUrl":"https://doi.org/10.1021/cen-10135-buscon9","url":null,"abstract":"The high-throughput experimentation company HTE is working with Stanford University chemistry professor Matthew Kanan on catalysts that make carbon monoxide from carbon dioxide. Metal-free reverse water-gas shift catalysts were tested for 3 months in HTE’s high-throughput units to get results that would have taken many years to obtain in his own lab, Kanan says . The ultimate hope is to be able to make chemicals and fuels from CO 2 emissions and hydrogen. Kanan says the performance of the catalysts has been encouraging for future scale-up.","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"42 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135367260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1021/cen-10135-buscon14
None Rick Mullin
Thermo Fisher Scientific will acquire the Swedish proteomics specialist Olink for $3.1 billion. Drawing on a library of 5,300 validated protein biomarkers, Olink has developed a high-throughput analysis platform for protein sequencing. The company has operations in the US and Asia as well as Europe. Olink’s proteomics capabilities will complement Thermo Fisher’s mass spectrometry and other assets in life sciences technology, Thermo Fisher CEO Marc N. Casper says in a press release announcing the deal. The sale is likely to be completed by mid-2024.
赛默飞世尔科技将以31亿美元收购瑞典蛋白质组学专家Olink。利用5300个经过验证的蛋白质生物标记物库，Olink开发了一个高通量的蛋白质测序分析平台。该公司在美国、亚洲和欧洲都有业务。赛默飞世尔首席执行官Marc N. Casper在宣布该交易的新闻发布会上表示，Olink的蛋白质组学能力将补充赛默飞世尔的质谱和其他生命科学技术资产。这笔交易可能会在2024年中期完成。
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Pub Date : 2023-10-23DOI: 10.1021/cen-10135-buscon17
None Laurel Oldach
The US Food and Drug Administration has approved the Pfizer ulcerative colitis drug etrasimod. The oral drug, trade named Velsipity, targets a subset of receptors for the inflammatory signaling molecule sphingosine-1-phosphate. Ulcerative colitis is an inflammatory colon condition that can cause severe bloody diarrhea and abdominal pain. Patients can be treated with steroids, biologics, or JAK inhibitors. Pfizer says Velsipity has an edge because it is available as a once-a-day pill. Pfizer acquired the drug when it bought Arena Pharmaceuticals in 2022. The company is also developing etrasimod for Crohn’s disease and for inflammatory conditions of the skin, esophagus, and scalp.
{"title":"FDA approves Pfizer’s Velsipity","authors":"None Laurel Oldach","doi":"10.1021/cen-10135-buscon17","DOIUrl":"https://doi.org/10.1021/cen-10135-buscon17","url":null,"abstract":"The US Food and Drug Administration has approved the Pfizer ulcerative colitis drug etrasimod. The oral drug, trade named Velsipity, targets a subset of receptors for the inflammatory signaling molecule sphingosine-1-phosphate. Ulcerative colitis is an inflammatory colon condition that can cause severe bloody diarrhea and abdominal pain. Patients can be treated with steroids, biologics, or JAK inhibitors. Pfizer says Velsipity has an edge because it is available as a once-a-day pill. Pfizer acquired the drug when it bought Arena Pharmaceuticals in 2022. The company is also developing etrasimod for Crohn’s disease and for inflammatory conditions of the skin, esophagus, and scalp.","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"24 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135366834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-23DOI: 10.1021/cen-10135-feature1
None Virat Markandeya, special to C&EN
Tucked away in Tamil Nadu, a state at India’s southern tip, is a facility run by members of the Irula tribe, an ethnic group known internationally for a long tradition of snake handling . Because it’s the only large-scale venom extraction facility in India, antivenom manufacturers in the country have depended on the Irula snake catchers cooperative for about 45 years. But this dependence has created a problem that’s tough to unravel. The cooperative’s venom samples are particular to the region. Species these snake handlers work with are found in many parts of India, but even within the same species, snakes have developed varying recipes and proportions of toxic proteins in their venoms. Ultimately, this means many antivenoms developed on the basis of samples from Tamil Nadu aren’t as effective against snakebites elsewhere in India, a country with tens of thousands of snakebite-related deaths per year, the highest total in
{"title":"Snake venom treatments leverage evolution","authors":"None Virat Markandeya, special to C&EN","doi":"10.1021/cen-10135-feature1","DOIUrl":"https://doi.org/10.1021/cen-10135-feature1","url":null,"abstract":"Tucked away in Tamil Nadu, a state at India’s southern tip, is a facility run by members of the Irula tribe, an ethnic group known internationally for a long tradition of snake handling . Because it’s the only large-scale venom extraction facility in India, antivenom manufacturers in the country have depended on the Irula snake catchers cooperative for about 45 years. But this dependence has created a problem that’s tough to unravel. The cooperative’s venom samples are particular to the region. Species these snake handlers work with are found in many parts of India, but even within the same species, snakes have developed varying recipes and proportions of toxic proteins in their venoms. Ultimately, this means many antivenoms developed on the basis of samples from Tamil Nadu aren’t as effective against snakebites elsewhere in India, a country with tens of thousands of snakebite-related deaths per year, the highest total in","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"50 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135367093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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