Pub Date : 2023-10-30DOI: 10.1021/cen-10136-feature4
None Andy Brunning, special to C&EN
Chemical educator and Compound Interest blogger Andy Brunning explores the colorful chemistry behind this classic Halloween candy To download a pdf of this article, visit http://cenm.ag/candycorn. References used to create this graphic: Bryk, Nancy E. V. “Candy Corn.” How Products Are Made. Accessed Oct. 18, 2023. BytesizeScience. “Candy Corn Chemistry!” Oct. 26, 2011. YouTube video, 1:13. Hartel, Richard W., and AnnaKate Hartel. Candy Bites: The Science of Sweets . New York: Copernicus, 2014. DOI: 10.1007/978-1-4614-9383-9 . A collaboration between C&EN and Andy Brunning, author of the popular graphics blog Compound Interest To see more of Brunning’s work, go to compoundchem.com. To see all of C&EN’s Periodic Graphics, visit http://cenm.ag/periodicgraphics .
化学教育家兼复利博客作者安迪·布伦宁探索了这种经典万圣节糖果背后丰富多彩的化学成分。用于制作这张图的参考资料:Bryk, Nancy E. V.“Candy Corn”。产品是如何制造的。访问日期为2023年10月18日。BytesizeScience。“玉米糖化学!”2011年10月26日YouTube视频，1:13。Richard W. Hartel和AnnaKate Hartel。糖果咬:糖果的科学。纽约:哥白尼出版社，2014。Doi: 10.1007/978-1-4614-9383-9。这是C&EN和Andy Brunning(流行的图形博客Compound Interest的作者)之间的合作。想看更多Brunning的作品，请访问compoundchem.com。要查看C&EN的所有周期图形，请访问http://cenm.ag/periodicgraphics。
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Pub Date : 2023-10-30DOI: 10.1021/cen-10136-buscon6
None Matt Blois
Merger and acquisition activity in the lithium industry is moving at a brisk pace. Azure Minerals, which is developing a lithium mine in Australia, has accepted a takeover bid from Chile’s SQM that values Azure at more than $1 billion . The deal requires 75% shareholder approval. In July, Azure rejected a $585 million bid from SQM, which is the company’s largest shareholder with a roughly 20% stake. SQM has also made smaller investments in early-stage lithium miners. It recently agreed to buy a minority stake in Pirra Lithium and is financing exploration activities for Dart Mining in return for equity interest. In addition, Chile’s state-owned mining company, Codelco, will acquire Lithium Power International in a deal worth $244 million. Lithium Power is developing a lithium mine in Chile’s Maricunga salt flat. These acquisition moves follow the recent collapse of Albemarle’s offer to acquire Liontown Resources in a $4.3 billion
锂行业的并购活动正在快速发展。正在澳大利亚开发锂矿的Azure Minerals已经接受了智利SQM的收购要约，该公司对Azure的估值超过10亿美元。该交易需要75%的股东批准。今年7月，Azure拒绝了SQM 5.85亿美元的收购要约。SQM是Azure最大的股东，持有约20%的股份。SQM还对早期锂矿企业进行了规模较小的投资。该公司最近同意收购皮拉锂业(Pirra Lithium)的少数股权，并为Dart Mining的勘探活动提供资金，以换取股权。此外，智利国有矿业公司Codelco将以2.44亿美元的价格收购Lithium Power International。Lithium Power正在智利Maricunga盐滩开发一个锂矿。在这些收购行动之前，Albemarle最近以43亿美元收购Liontown Resources的提议失败了
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Pub Date : 2023-10-30DOI: 10.1021/cen-10136-buscon16
None Laura Howes
{"title":"Roche buys Telavant for $7.1 billion","authors":"None Laura Howes","doi":"10.1021/cen-10136-buscon16","DOIUrl":"https://doi.org/10.1021/cen-10136-buscon16","url":null,"abstract":"","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"255 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136102823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.1021/cen-10136-buscon14
None Rick Mullin
Isotope Technologies Munich (ITM), a German radiopharmaceutical firm, and Canadian Nuclear Laboratories (CNL) are forming a joint venture for the industrial-scale production of actinium-225 ( 225 Ac). The rare, α-emitting medical radioisotope is of interest as a precision oncology therapy. The venture, Actineer, plans to build a dedicated actinium production facility in an unspecified location. It will begin supplying 225 Ac in the interim; CNL will provide starting material for irradiation at its laboratory in Chalk River, Ontario, and ITM will process the resulting 225 Ac to pharmaceutical-grade material. CNL operates a national laboratory at Chalk River on behalf of Atomic Energy of Canada.
{"title":"Firms launch an actinium-225 venture","authors":"None Rick Mullin","doi":"10.1021/cen-10136-buscon14","DOIUrl":"https://doi.org/10.1021/cen-10136-buscon14","url":null,"abstract":"Isotope Technologies Munich (ITM), a German radiopharmaceutical firm, and Canadian Nuclear Laboratories (CNL) are forming a joint venture for the industrial-scale production of actinium-225 ( 225 Ac). The rare, α-emitting medical radioisotope is of interest as a precision oncology therapy. The venture, Actineer, plans to build a dedicated actinium production facility in an unspecified location. It will begin supplying 225 Ac in the interim; CNL will provide starting material for irradiation at its laboratory in Chalk River, Ontario, and ITM will process the resulting 225 Ac to pharmaceutical-grade material. CNL operates a national laboratory at Chalk River on behalf of Atomic Energy of Canada.","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"30 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136022680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.1021/cen-10136-buscon1
None Alla Katsnelson, special to C&EN
The gene-editing company Beam Therapeutics on Oct. 19 became the latest biotech firm to announce staff layoffs. It plans to cut 100 employees, or 20% of its workforce. The Cambridge, Massachusetts–based firm also says it will pare back its pipeline. The cost savings from these changes will keep the company going into 2026, according to Beam. Chemist David R. Liu of the Broad Institute of MIT and Harvard launched Beam in May 2018 —2 years after his lab developed base editors , the firm’s key technology. Base editors deliver a twist on traditional CRISPR-Cas gene editing to make single nucleotide base changes in DNA. In theory, this technology enables the treatment of genetic diseases with more precision and with fewer off-target effects. But despite base editing’s potential, it’s taking time for the technology to yield a clinical product. Beam’s restructuring will pause the development of an in vivo treatment for
10月19日，基因编辑公司Beam Therapeutics成为最新一家宣布裁员的生物技术公司。该公司计划裁员100人，占员工总数的20%。这家总部位于马萨诸塞州剑桥的公司还表示，它将削减其管道。根据Beam的说法，这些变化节省的成本将使公司维持到2026年。2018年5月，麻省理工学院和哈佛大学布罗德研究所的化学家David R. Liu推出了Beam，两年前，他的实验室开发出了该公司的关键技术碱基编辑器。碱基编辑器对传统的CRISPR-Cas基因编辑进行了改良，使DNA中的单个核苷酸碱基发生变化。理论上，这项技术可以更精确地治疗遗传疾病，减少脱靶效应。但是，尽管碱基编辑具有潜力，但这项技术要产生临床产品还需要时间。Beam的重组将暂停体内治疗的发展
{"title":"Beam Therapeutics lays off staff, adjusts research focus","authors":"None Alla Katsnelson, special to C&EN","doi":"10.1021/cen-10136-buscon1","DOIUrl":"https://doi.org/10.1021/cen-10136-buscon1","url":null,"abstract":"The gene-editing company Beam Therapeutics on Oct. 19 became the latest biotech firm to announce staff layoffs. It plans to cut 100 employees, or 20% of its workforce. The Cambridge, Massachusetts–based firm also says it will pare back its pipeline. The cost savings from these changes will keep the company going into 2026, according to Beam. Chemist David R. Liu of the Broad Institute of MIT and Harvard launched Beam in May 2018 —2 years after his lab developed base editors , the firm’s key technology. Base editors deliver a twist on traditional CRISPR-Cas gene editing to make single nucleotide base changes in DNA. In theory, this technology enables the treatment of genetic diseases with more precision and with fewer off-target effects. But despite base editing’s potential, it’s taking time for the technology to yield a clinical product. Beam’s restructuring will pause the development of an in vivo treatment for","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"153 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136023359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.1021/cen-10136-buscon9
None Michael McCoy
{"title":"Sumitomo plans propylene from ethanol","authors":"None Michael McCoy","doi":"10.1021/cen-10136-buscon9","DOIUrl":"https://doi.org/10.1021/cen-10136-buscon9","url":null,"abstract":"","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136105006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.1021/cen-10136-buscon11
None Alex Tullo
{"title":"Vinyl records could be things of the past","authors":"None Alex Tullo","doi":"10.1021/cen-10136-buscon11","DOIUrl":"https://doi.org/10.1021/cen-10136-buscon11","url":null,"abstract":"","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136070088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.1021/cen-10136-buscon13
None Alex Tullo
{"title":"Borealis signs wind energy pact","authors":"None Alex Tullo","doi":"10.1021/cen-10136-buscon13","DOIUrl":"https://doi.org/10.1021/cen-10136-buscon13","url":null,"abstract":"","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"123 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136104776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.1021/cen-10136-acsnews1
None Sabrina J. Ashwell
{"title":"Recognizing diversity in gender and sexuality and body size","authors":"None Sabrina J. Ashwell","doi":"10.1021/cen-10136-acsnews1","DOIUrl":"https://doi.org/10.1021/cen-10136-acsnews1","url":null,"abstract":"","PeriodicalId":9517,"journal":{"name":"C&EN Global Enterprise","volume":"26 10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136102607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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