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Pyrum eyes tire recycling in Czechia 捷克的Pyrum着眼于轮胎回收
Pub Date : 2023-11-13 DOI: 10.1021/cen-10137-buscon13
None Alex Scott
The German tire recycling firm Pyrum Innovations plans to build a plant that would recycle up to 20,000 metric tons of used tires per year in Czechia. The plant is slated to start up in 2025. Pyrum estimates that its pyrolysis technology generates 2.5 L of oil, 5 kg of carbon black, and smaller amounts of textile fibers and steel wire from each tire it recycles. The firm aims to build more than 17 new plants by 2030.
德国轮胎回收公司Pyrum Innovations计划在捷克建立一个工厂,每年回收多达2万吨旧轮胎。该工厂计划于2025年投产。Pyrum估计,其热解技术从每个回收的轮胎中产生2.5升石油、5公斤炭黑,以及少量的纺织纤维和钢丝。该公司的目标是到2030年建造超过17座新工厂。
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引用次数: 0
Classifieds 分类广告
Pub Date : 2023-11-13 DOI: 10.1021/cen-10137-classifieds
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引用次数: 0
Beckman Coulter, 10x partner on single-cell assays 贝克曼·库尔特,单细胞化验的10倍合伙人
Pub Date : 2023-11-13 DOI: 10.1021/cen-10137-buscon15
None Rick Mullin
Beckman Coulter Life Sciences and 10x Genomics have formed a partnership to advance single-cell assay workflow automation. Under the agreement, 10x intends to develop customized single-cell kits to be used with Beckman’s Biomek i7 automated liquid-handling systems—providing finished libraries ready for sequencing. The partnership will focus on high-throughput library preparation and streamlined simultaneous processing. Single-cell methods are becoming more important in therapeutic areas such as oncology, immunology, and neuroscience.
贝克曼库尔特生命科学公司和10x基因组公司已经形成了合作伙伴关系,以推进单细胞分析工作流程自动化。根据协议,10x打算开发定制的单细胞试剂盒,与Beckman的Biomek i7自动液体处理系统一起使用,为测序提供完整的文库。该合作伙伴关系将集中在高通量库准备和简化的同步处理上。单细胞方法在肿瘤学、免疫学和神经科学等治疗领域变得越来越重要。
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引用次数: 0
Ads 广告
Pub Date : 2023-11-13 DOI: 10.1021/cen-10137-ads
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引用次数: 0
Dorothy J. Phillips voted 2024 ACS president-elect 桃乐丝·菲利普斯(Dorothy J. Phillips)投票当选2024年ACS总统
Pub Date : 2023-11-13 DOI: 10.1021/cen-10137-leadcon
None Sara Cottle
Dorothy J. Phillips , retired from the role of director of strategic marketing at Waters, has been voted the American Chemical Society 2024 president-elect by members of ACS. Phillips will serve as society president in 2025 and immediate past president in 2026. The appointment also includes serving on the board of directors from 2024 through 2026. A total of 11,428 votes were cast for president-elect. Voter participation was 12% of all eligible voters. With 6,653 votes, Phillips won the president-elect race against Florian J. Schattenmann, chief technology officer and vice president of research and development and innovation at Cargill, who received 4,775 votes. Members of ACS, which publishes C&EN, also elected four other people into ACS positions and voted on a petition that was up for approval in the fall 2023 election cycle. “Excited, blessed, happy, thankful. This is really a blessing for me to achieve this milestone,” Phillips says.
Dorothy J. Phillips,从沃特斯公司战略营销总监的职位退休,被ACS成员投票选为2024年美国化学学会当选主席。菲利普斯将于2025年担任学会会长,并于2026年担任即将卸任的会长。该任命还包括在2024年至2026年期间担任董事会成员。当选总统共获得11428张选票。选民投票率为所有合格选民的12%。菲利普斯以6653票击败了获得4775票的嘉吉公司首席技术官兼研发和创新副总裁弗洛里安·j·沙腾曼,赢得了当选总统的竞选。出版C&EN的ACS成员还选举了另外四人进入ACS职位,并就一份请愿书进行了投票,该请愿书将在2023年秋季的选举周期中获得批准。兴奋、幸福、快乐、感激。能达到这个里程碑对我来说真的是一种祝福,”菲利普斯说。
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引用次数: 0
Single-molecule snapshots of glycans 聚糖的单分子快照
Pub Date : 2023-11-13 DOI: 10.1021/cen-10137-scicon5
None XiaoZhi Lim, special to C&EN
By pairing up techniques, researchers have produced images of individual molecules of a variety of glycans, or carbohydrate molecules, that are found on proteins or lipids. The images of these carbohydrate molecules are at such high resolutions that scientists could see and count every monosaccharide at every glycosylated site. “I’ve been making glycopeptides and glycoproteins for 25 years,” says Matthew Pratt , a carbohydrate chemist at the University of Southern California who was not involved in the research. He has long imagined how sugar molecules might look attached to protein backbones. “Reading this paper and seeing the striking results were like watching my thoughts and figures come to life.” Complex carbohydrates attached to proteins, lipids, or the outside of biological cells play major roles in cellular signaling and other biological functions . Studying their interactions helps researchers understand cellular interactions and develop new therapeutics based on disrupting or enhancing those
通过配对技术,研究人员已经产生了蛋白质或脂质上发现的各种聚糖或碳水化合物分子的单个分子的图像。这些碳水化合物分子的图像分辨率如此之高,以至于科学家们可以看到并计算每个糖基化位点上的每个单糖。“我制造糖肽和糖蛋白已经有25年了,”南加州大学的碳水化合物化学家马修·普拉特(Matthew Pratt)说,他没有参与这项研究。长期以来,他一直在想象糖分子附着在蛋白质骨架上的样子。“阅读这篇论文,看到惊人的结果,就像看着我的思想和数字活过来一样。”附着在蛋白质、脂质或生物细胞外部的复合碳水化合物在细胞信号传导和其他生物功能中起着重要作用。研究它们之间的相互作用有助于研究人员了解细胞之间的相互作用,并开发基于破坏或增强这些相互作用的新疗法
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引用次数: 0
Halda Therapeutics Halda疗法
Pub Date : 2023-11-13 DOI: 10.1021/cen-10137-cover7
None Gina Vitale
Craig Crews is no stranger to the challenge of devising a punchy name for a new class of drug. The chemical biologist was involved in both the discovery and the naming of proteolysis-targeting chimeras, or PROTACs, which are double-ended molecules that degrade proteins. When Crews founded Halda Therapeutics to develop another new class of drug, he and the leadership team—including Executive Chair Tim Shannon and Chief Scientific Officer Kat Kayser-Bricker—wanted to give these molecules a moniker that’s a little graver. “We wanted to kill cells,” Crews says. “We had to figure out a way to make sure that RIP found its way into the name.” And so regulated induced proximity targeting chimeras, or RIPTACs, were christened. As the moniker suggests, a double-ended RIPTAC brings two proteins together. With one end, it binds a protein that is overexpressed in a tumor, which helps the RIPTAC get to, and stay inside, the
克雷格·克鲁斯(Craig Crews)对为一类新毒品想出一个有力的名字并不陌生。这位化学生物学家参与了蛋白水解靶向嵌合体(PROTACs)的发现和命名,这是一种降解蛋白质的双端分子。当克鲁斯成立哈尔达治疗公司开发另一类新药时,他和领导团队——包括执行主席蒂姆·香农和首席科学官凯特·凯瑟-布里克——想给这些分子起一个更严肃的名字。“我们想杀死细胞,”克鲁斯说。“我们必须找到一种方法,确保RIP在名字中找到了一席之地。”因此,调控诱导近距离靶向嵌合体(简称riptac)被命名。顾名思义,双端RIPTAC将两种蛋白质结合在一起。它的一端与肿瘤中过度表达的蛋白质结合,帮助RIPTAC进入并留在肿瘤内部
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引用次数: 0
Chlorpyrifos returns to the US market 毒死蜱重回美国市场
Pub Date : 2023-11-13 DOI: 10.1021/cen-10137-polcon2
None Britt E. Erickson
In a win for farmers and pesticide makers, a federal appeals court has reopened the door for use of the organophosphate pesticide chlorpyrifos on food crops in some US states. A Nov. 2 ruling by the US Court of Appeals for the Eighth Circuit nixes a 2021 rule issued by the Environmental Protection Agency banning the neurotoxic insecticide on food. The court ruling also orders the EPA to reevaluate whether chlorpyrifos can be safely used on crops like sugar beets, soybeans, and certain fruits and vegetables. In its opinion, the court notes that the EPA failed to consider “its own proposal to keep a set of high-benefit uses in place.” The agency was under a short, court-ordered deadline to make a decision about whether to cancel all uses of chlorpyrifos on food or show that anticipated uses are safe. The agency zeroed in on a single solution—banning all uses of
美国一家联邦上诉法院重新打开了在一些州对粮食作物使用有机磷农药毒死蜱的大门,这对农民和农药制造商来说是一场胜利。11月2日,美国第八巡回上诉法院的一项裁决否决了美国环境保护局2021年发布的一项禁止在食品中使用这种神经毒性杀虫剂的规定。法院的裁决还命令环保署重新评估毒死蜱是否可以安全地用于甜菜、大豆和某些水果和蔬菜等作物。法院在其意见中指出,环保署未能考虑到“它自己提出的保留一系列高效益用途的建议”。在法院下达的短暂最后期限内,该机构必须决定是取消所有毒死蜱在食品中的使用,还是证明预期的使用是安全的。该机构把注意力集中在一个单一的解决方案上——禁止使用所有的
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引用次数: 0
Air Products to make blue H2 in Rotterdam 空气产品公司将在鹿特丹生产蓝色氢气
Pub Date : 2023-11-13 DOI: 10.1021/cen-10137-buscon11
None Alex Scott
Air Products plans to build and operate a facility to capture carbon dioxide emissions from an existing fossil fuel–consuming hydrogen plant that supplies ExxonMobil’s refinery in Rotterdam, the Netherlands. Due to start up in 2026, the carbon capture facility would make the Air Products plant the biggest producer of blue hydrogen in Europe, the company claims. The captured CO 2 would be piped into an empty gas field 3 km beneath the North Sea. Financial details were not disclosed.
空气产品公司计划建造并运营一个设施,以捕获现有的消耗化石燃料的氢气厂排放的二氧化碳,该工厂为埃克森美孚在荷兰鹿特丹的炼油厂提供燃料。空气产品公司声称,由于碳捕获设施将于2026年启动,该工厂将成为欧洲最大的蓝氢生产商。捕获的二氧化碳将通过管道输送到北海下方3公里处的一个空气田。财务细节没有披露。
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引用次数: 0
Elicit Plant 引起植物
Pub Date : 2023-11-13 DOI: 10.1021/cen-10137-cover5
None Britt E. Erickson
Water scarcity is a challenge for farmers in many regions, and climate change is making the problem worse. The French start-up Elicit Plant is tapping into the power of phytosterols to help boost yields for row crops like corn, soybeans, wheat, and sunflowers in the face of growing water shortages. Phytosterols are lipids that form part of cell membranes in plants. They function as signaling molecules that trigger growth and other adaptive responses when plants are under stress. The chemicals have been used in cosmetic, health, and nutrition applications, but Elicit is the first to apply them to agriculture, according to CEO and cofounder Jean-François Déchant. Elicit’s first commercial product, Best-a corn, contains a mixture of phytosterols extracted from plants. They’re designed specifically to increase corn yields under dry conditions. When taken up by the plants through their leaves, the phytosterols act as messengers, signaling to the plant to do
水资源短缺对许多地区的农民来说是一个挑战,而气候变化正在使这个问题变得更糟。法国初创企业Elicit Plant正在利用植物甾醇的力量来帮助提高玉米、大豆、小麦和向日葵等行作物的产量,以应对日益严重的水资源短缺。植物甾醇是构成植物细胞膜一部分的脂质。它们作为信号分子,在植物受到压力时触发生长和其他适应性反应。该公司首席执行官兼联合创始人让-弗朗索瓦•达姆尚表示,这些化学品已被用于化妆品、健康和营养领域,但诱出公司是第一家将其应用于农业的公司。Elicit的第一款商业产品Best-a玉米含有从植物中提取的植物甾醇混合物。它们是专门为在干旱条件下提高玉米产量而设计的。当植物通过叶子吸收这些甾醇时,它们就像信使一样,向植物发出指令
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