ChemistryOpen最新文献

Quinazolines/quinazolin-4-ones are significant nitrogen-containing heterocycles that exist in various natural products and synthetic scaffolds with diverse medicinal and pharmacological applications. Researchers across the globe have explored numerous synthetic strategies to develop safer and more potent quinazoline/quinazolinone analogues, particularly for combating cancer and microbial infections. This review systematically examines scholarly efforts toward understanding this scaffold's synthetic pathways and medicinal relevance, emphasizing the role of metal and non-metal catalysts and other reagents in their synthesis. Additionally, the article discusses selected compounds' anticancer and antimicrobial properties, with a brief look into their structure-activity relationships.

Nanoparticles enhance agricultural applications with their bioactivity, bioavailability, and reactivity. Selenium mitigates the adverse effects of salinity on plant growth, boosting antioxidant defense, metabolism, and resilience to abiotic stress. Our study applied selenium nanoparticles to mitigate salinity-induced damage and support plant growth. We characterized green-synthesized nanoparticles and analyzed stress-related metabolites, antioxidant activities (DPPH, ABTS), phenolic content, and reducing powers (CUPRAC, FRAP). Nanoparticle applications reduced proline and MDA levels while boosting chlorophyll, carotenoids, antioxidant activity (DPPH, ABTS), and total phenolic content. An increase was also observed in CUPRAC and FRAP reducing capacities. In terms of phenolic content, the highest value was determined in SA₁ (4.58±0.40 mg GAE g^-1) application; DPPH free radical scavenging activity IC50 value was determined in A₃ (0.13±0.007 mg mL^-1) application, which was closest to the positive control. The lowest proline level was found in A₃ (15.00±0.64 nmol g^-1 FW) and the lowest MDA level was found in SA₃ (10.08±0.42 nmol g^-1). Comparing the results, green synthesis of selenium nanoparticles using Sternbergia candida (SC-SeNP) at different concentrations showed ameliorative effects on various parameters in plants, and it was determined that the effects of salt stress on pepper plants were reduced following SC-SeNP applications.

The rapid proliferation of internet-connected devices has transformed our daily habits prompting a shift towards greater sustainability in renewable energy for indoor applications. Among the various technologies available for obtaining energy in indoor conditions, Dye-Sensitized Solar Cells (DSSCs) stand out as the most promising due to their ability to efficiently convert ambient light into usable electricity. This study explores how the optimal matching of the UV-Vis absorption spectra of dyes commonly used in DSSCs with the emission profiles of indoor lamps allows for the enhanced efficiency of DSSC under indoor lighting. By testing four organic dyes with different UV-Vis absorption spectra (L1, Y123, S1, and TP1) under two different common indoor light sources (OSRAM 930 and OSRAM 765 lamp), a significant dye-lamp correlation was demonstrated. Notably, low-priced dyes like S1 and TP1, characterized by easier synthetic routes and with an optimal overlap with the dye-lamp spectrum, exhibited competitive efficiencies, narrowing the performance gap with high-performing dyes like Y123, which require more demanding preparation approaches. The study highlights the critical importance of tailoring dye selection to specific indoor lighting environments, addressing a significant gap and paving the way for more sustainable and cost-effective energy solutions for indoor applications.

The alga contains salt and heavy metals that are accumulated in algae poses a significant challenge to the safe use of algae in soil fertilization and other applications. This study examines the relevance of algal biomass as an environmentally friendly fertilizer, thereby contributing to sustainable coastal management practices. In this study, the hot and cold extraction method were done to obtain the Ulva rigida extract. Heavy metals such as vanadium, chromium, manganese, iron, nickel, cobalt, copper, zinc and cadmium etc. were analyzed using ICP-MS. Heavy metal analysis showed that the major metals such as manganese, iron, vanadium and zinc in Ulva rigida extract. The algae extract was used in different concentration (20, 40, 60 and 80 μL) to analyze the seed germination study in Pennisetum glaucum and it was found that theseed germination were 100 % at 5^th day after sowing and the root and shoot length increased with increasing concentration of Ulva rigida extract and at 80 μL the shoot length of Pennisetum glaucum were decreased. The aqueous extracts of Ulva rigida are eco-friendly, safe method for recycling the algal biomass as a novel biofertilizer.

The direct electrochemical carboxylation of aryl, benzyl and alkyl halides by CO₂ is described using a magnesium anode and a nickel foam cathode in an undivided cell. The process employs a sacrificial anode and does not require the additional use of a transition metal catalyst or demanding conditions, as the reactions are carried out under galvanostatic mode, at -10 °C and with commercial DMF. Under these operationally simple conditions, an important range of carboxylic acids are affordable. Mechanistic investigation account for the in situ generation of a carbanionic species that is not a simple organomagnesium halide.

This study explores the synthesis of ZSM-5 zeolite using high-purity mesoporous silica exclusively derived from coal fly ash (CFA), eliminating the need for additional silica or alumina sources. Traditional ZSM-5 synthesis relies on costly and environmentally harmful pure chemicals, whereas this approach utilizes CFA, an industrial byproduct, addressing both cost and sustainability concerns. The synthesized ZSM-5 zeolite demonstrates exceptional purity, with a surface area of 455.24 m²/g, and exhibits unique structural properties, confirmed through XRD, SEM, TEM, FTIR, TGA, and BET analyses. This method highlights the potential of CFA-derived silica as a sustainable feedstock for zeolite production, promoting both environmental sustainability and cost-effective industrial applications in catalysis, adsorption, and separation processes.

Conversion of glycerol to added-value products is desirable due to its surplus during biodiesel synthesis. TiO₂ has been the most explored catalyst. We performed a systematic study of glycerol adsorption on anatase (101), anatase (001), and rutile (110) TiO₂ at the Density Functional Theory level. We found several adsorption modes on these surfaces, with anatase (101) being the less reactive one, leading to adsorption energies between -0.8 and -0.4 eV, with all adsorptions molecular in nature. On the contrary, anatase (001) is the most reactive surface, leading to both molecular and dissociative adsorption modes, with energies ranging from -4 to -1 eV and undergoing severe surface reconstructions in some cases. Rutile (110) also shows both molecular and dissociative adsorptions, but it is less reactive than anatase (001). Surfaces with oxygen vacancies affects the adsorbed states and energies. The electronic structure analysis reveals that glycerol adsorption mainly affects the band gap of the material and not the individual contributions to the valence and conduction band. Bader charge analysis shows that strong adsorption modes on anatase (001) and rutile (110) are associated with large charge transfer from glycerol to the surface, while weak and molecular adsorption modes involve low charge transfer.

To better understand how the biocatalyzed depolymerization of polyesters works, model molecules are needed to develop activity assays and determine enzymatic kinetic parameters. In this communication the chemical synthesis and characterization of 2-hydroxyethyl furan-5-carboxylic acid and bis(2-hydroxyethyl) furan-2,5-dicarboxylates as potential model molecules to further study the enzymatic depolymerization of poly(ethylene furanoate) was investigated.

Self-powered devices for human motion monitoring and energy harvesting have garnered widespread attention in recent research. In this work, we designed a honeycomb-structured triboelectric nanogenerator (H-TENG) using polyester cloth and Teflon tape, with aluminum foil as the conductive electrode. This design leverages the large surface area and flexibility of textiles, resulting in significant performance improvements. The H-TENG achieves an output voltage of 350 V, an output current of 42 μA, and a transfer charge (Q_SC) of 77 nC, with a maximum output power of 465 μW. Additionally, the H-TENG demonstrates the ability to monitor running activities and various gait patterns, providing real-time bio-mechanical data for smart running applications. The introduction of a stacked structure further enhances the output performance by increasing contact area and scalability, making the H-TENG a robust and high-performance energy harvester suitable for advanced wearable and flexible electronics.

High-entropy alloys (HEAs), containing five or more elements in equal proportions, have recently made significant achievements in materials science due to their remarkable properties, including high toughness, excellent catalytic, thermal, and electrical conductivity, and resistance to wear and corrosion. This study focuses on a HEA composed of 23Fe-21Cr-18Ni-20Ti-18Mn, synthesized via ball milling. The alloy was treated with hydrochloric acid (HCl) to enhance its active surface area. The untreated HEA and the HCl-treated HEA (HEA-T) were then evaluated as potential cathode materials for supercapacitors (SCs). X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDX) confirmed that the HEA's composition and crystalline structure remained stable during acid treatment, with no new phases forming. The acid treatment significantly increased the surface area by ~20 times, the pore volume by ~10 times, and improved microstructural homogeneity. The HEA-T electrode demonstrated superior specific capacitance, lower internal resistance, and better cycling stability than the untreated HEA electrode. At 0.5 A/g current density, the specific capacitance (Csp) of the HEA-T was 600 F/g, approximately two times higher than the untreated HEA. This enhanced performance suggests that the HEA-T electrode could lead to the development of high-performance SCs.