首页 > 最新文献

Archives of Gerontology and Geriatrics Plus最新文献

英文 中文
Efficacy and safety of gantenerumab in the treatment of Alzheimer's disease: A meta-analysis of randomized controlled trials 甘特宁单抗治疗阿尔茨海默病的疗效和安全性:随机对照试验荟萃分析
Pub Date : 2024-03-05 DOI: 10.1016/j.aggp.2024.100016
Milene Vitória Sampaio Sobral , Victor Gonçalves Soares , Ocilio Ribeiro Gonçalves , Victoria Städler de Abreu , Lucas Cael Azevedo Ramos Bendaham , Brenda Leticia Lopes Batista M.D. , Marco Antonnio Rocha dos Santos M.D., MsC

Introduction

Gantenerumab has garnered considerable attention for its potential to modify the natural course of Alzheimer's disease. However, recent studies have shown mixed results for the use of this medication for the treatment of Alzheimer's Disease. Therefore, this review compared the effects of Gantenerumab with placebo in patients with Alzheimer's disease.

Methods

Literature searches were conducted in PubMed, Embase and Cochrane database from inception to December 2023. Two independent authors (MS and LV) performed the study selection, data extraction and quality assessment. The outcomes of this review were: Clinical Dementia Rating - Sum of Boxes (CDR-SB), the Alzheimer's Disease Assessment Scale (ADAS-Cog), the Mini-Mental State Evaluation (MMSE) and the incidence of Amyloid-Related Imaging Abnormalities with Edema (ARIA-E) or Amyloid-Related Imaging Abnormalities with Hemosiderosis (ARIA-H). Meta-analysis were performed using Review Manager 5.4 (Cochrane Collaboration).

Results

Four studies reporting data for 2,848 patients were included in this review. The lenght of follow-up assessments ranged from 50 to 104 weeks. When compared to placebo, Gantenerumab was significantly associated with a lower ADAS-Cog score (MD -1.05; 95 % CI: -1.85 to -0.25) and lower MMSE score (MD -0.31; 95 % CI: -0.55 to -0.07). There were no differences in the CDR-SB score. Gantenerumab group had a higher incidence of ARIA-E (RR 8.94; 95 % CI: 6.22 to 12.84).

Conclusion

Gantenerumab showed negative effects on cognitive outcomes of people with Alzheimer's Disease. There was a higher incidence of ARIA-E and ARIA-H for gantenerumab. Additional high quality studies are needed to draw more robust conclusions about this treatment.

导言 甘特奈鲁单抗因其改变阿尔茨海默病自然病程的潜力而备受关注。然而,最近的研究显示,使用这种药物治疗阿尔茨海默病的结果好坏参半。因此,本综述比较了甘特宁单抗与安慰剂对阿尔茨海默病患者的治疗效果。方法在 PubMed、Embase 和 Cochrane 数据库中进行文献检索,检索时间从开始至 2023 年 12 月。两位独立作者(MS 和 LV)进行了研究筛选、数据提取和质量评估。本综述的结果如下临床痴呆评级--方框总和(CDR-SB)、阿尔茨海默病评估量表(ADAS-Cog)、迷你精神状态评估(MMSE)以及淀粉样蛋白相关成像异常水肿(ARIA-E)或淀粉样蛋白相关成像异常血沉(ARIA-H)的发生率。使用Review Manager 5.4(Cochrane Collaboration)进行了荟萃分析。结果本综述纳入了四项研究,报告了2848名患者的数据。随访评估时间从 50 周到 104 周不等。与安慰剂相比,Gantenerumab与较低的ADAS-Cog评分(MD -1.05;95 % CI:-1.85至-0.25)和较低的MMSE评分(MD -0.31;95 % CI:-0.55至-0.07)显著相关。CDR-SB 评分没有差异。Gantenerumab 组的 ARIA-E 发生率更高(RR 8.94;95 % CI:6.22 至 12.84)。甘特纳单抗的ARIA-E和ARIA-H发生率较高。需要进行更多高质量的研究,才能对该疗法得出更可靠的结论。
{"title":"Efficacy and safety of gantenerumab in the treatment of Alzheimer's disease: A meta-analysis of randomized controlled trials","authors":"Milene Vitória Sampaio Sobral ,&nbsp;Victor Gonçalves Soares ,&nbsp;Ocilio Ribeiro Gonçalves ,&nbsp;Victoria Städler de Abreu ,&nbsp;Lucas Cael Azevedo Ramos Bendaham ,&nbsp;Brenda Leticia Lopes Batista M.D. ,&nbsp;Marco Antonnio Rocha dos Santos M.D., MsC","doi":"10.1016/j.aggp.2024.100016","DOIUrl":"https://doi.org/10.1016/j.aggp.2024.100016","url":null,"abstract":"<div><h3>Introduction</h3><p>Gantenerumab has garnered considerable attention for its potential to modify the natural course of Alzheimer's disease. However, recent studies have shown mixed results for the use of this medication for the treatment of Alzheimer's Disease. Therefore, this review compared the effects of Gantenerumab with placebo in patients with Alzheimer's disease.</p></div><div><h3>Methods</h3><p>Literature searches were conducted in PubMed, Embase and Cochrane database from inception to December 2023. Two independent authors (MS and LV) performed the study selection, data extraction and quality assessment. The outcomes of this review were: Clinical Dementia Rating - Sum of Boxes (CDR-SB), the Alzheimer's Disease Assessment Scale (ADAS-Cog), the Mini-Mental State Evaluation (MMSE) and the incidence of Amyloid-Related Imaging Abnormalities with Edema (ARIA-E) or Amyloid-Related Imaging Abnormalities with Hemosiderosis (ARIA-H). Meta-analysis were performed using Review Manager 5.4 (Cochrane Collaboration).</p></div><div><h3>Results</h3><p>Four studies reporting data for 2,848 patients were included in this review. The lenght of follow-up assessments ranged from 50 to 104 weeks. When compared to placebo, Gantenerumab was significantly associated with a lower ADAS-Cog score (MD -1.05; 95 % CI: -1.85 to -0.25) and lower MMSE score (MD -0.31; 95 % CI: -0.55 to -0.07). There were no differences in the CDR-SB score. Gantenerumab group had a higher incidence of ARIA-E (RR 8.94; 95 % CI: 6.22 to 12.84).</p></div><div><h3>Conclusion</h3><p>Gantenerumab showed negative effects on cognitive outcomes of people with Alzheimer's Disease. There was a higher incidence of ARIA-E and ARIA-H for gantenerumab. Additional high quality studies are needed to draw more robust conclusions about this treatment.</p></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 2","pages":"Article 100016"},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950307824000134/pdfft?md5=041a56c07fbd77175798d009e4f4f250&pid=1-s2.0-S2950307824000134-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140162749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 related health literacy and preventive behaviours of the older person in Perak state, Malaysia: A qualitative study COVID-19 马来西亚霹雳州老年人的相关健康知识和预防行为:定性研究
Pub Date : 2024-03-04 DOI: 10.1016/j.aggp.2024.100014
Xin-Jie Lim , Kok-Leong Tan , Gaik-Kin Teoh , Maw-Pin Tan

Introduction

Health literacy is crucial in controlling the spread of SARS-CoV2 and preventing infection, as well as preparing healthcare systems for situations that require immediate response. The aim of this study was to evaluate older people's health literacy towards disease prevention, as well as the motivators and barriers they experienced when adopting preventative measures.

Methods

We conducted in-depth interviews with 16 participants aged 65 and beyond. Purposive sampling was used to recruit participants, accounting for variability in gender, age and educational level. The transcripts were analysed using thematic analysis methods. The interview guide was developed using Sørensen's conceptual model of health literacy.

Results

Five main themes and 16 sub-themes were identified in this study. Knowledge and perception on preventive measures (with two sub-themes), sources of Covid-19 information (with two sub-themes), appraise the health information (with two sub-themes), perceived practice (with five sub-themes), barriers and motivators (with five sub-themes) were the major themes. This study discovered aspects of SEM may influence preventive measure adoption and the impact of different levels of SEM on seniors' decision-making for preventive measure adoption.

Conclusion

This study examined older adults' experiences with CoviD-19-related health literacy (access, comprehend, assess, and apply), as well as their preventative behaviours, barriers, and motivators. Future disease outbreak mitigation measures should consider the SEM approach in order to improve health communication and promote healthy behaviour.

引言 健康素养对于控制 SARS-CoV2 的传播、预防感染以及使医疗系统做好准备应对需要立即采取应对措施的情况至关重要。本研究旨在评估老年人对疾病预防的健康素养,以及他们在采取预防措施时遇到的动机和障碍。在招募参与者时,我们采用了有目的的抽样方法,考虑到了性别、年龄和教育水平方面的差异。访谈记录采用主题分析方法进行分析。本研究确定了五个主题和 16 个子主题。对预防措施的了解和看法(两个次主题)、Covid-19 信息的来源(两个次主题)、对健康信息的评价(两个次主题)、实践感知(五个次主题)、障碍和动机(五个次主题)是主要主题。本研究发现了 SEM 的各个方面可能会影响预防措施的采用,以及不同水平的 SEM 对老年人采用预防措施决策的影响。结论本研究考察了老年人在 CoviD-19 相关健康素养(获取、理解、评估和应用)方面的经验,以及他们的预防行为、障碍和动机。未来的疾病爆发缓解措施应考虑采用 SEM 方法,以改善健康传播和促进健康行为。
{"title":"COVID-19 related health literacy and preventive behaviours of the older person in Perak state, Malaysia: A qualitative study","authors":"Xin-Jie Lim ,&nbsp;Kok-Leong Tan ,&nbsp;Gaik-Kin Teoh ,&nbsp;Maw-Pin Tan","doi":"10.1016/j.aggp.2024.100014","DOIUrl":"https://doi.org/10.1016/j.aggp.2024.100014","url":null,"abstract":"<div><h3>Introduction</h3><p>Health literacy is crucial in controlling the spread of SARS-CoV2 and preventing infection, as well as preparing healthcare systems for situations that require immediate response. The aim of this study was to evaluate older people's health literacy towards disease prevention, as well as the motivators and barriers they experienced when adopting preventative measures.</p></div><div><h3>Methods</h3><p>We conducted in-depth interviews with 16 participants aged 65 and beyond. Purposive sampling was used to recruit participants, accounting for variability in gender, age and educational level. The transcripts were analysed using thematic analysis methods. The interview guide was developed using Sørensen's conceptual model of health literacy.</p></div><div><h3>Results</h3><p>Five main themes and 16 sub-themes were identified in this study. Knowledge and perception on preventive measures (with two sub-themes), sources of Covid-19 information (with two sub-themes), appraise the health information (with two sub-themes), perceived practice (with five sub-themes), barriers and motivators (with five sub-themes) were the major themes. This study discovered aspects of SEM may influence preventive measure adoption and the impact of different levels of SEM on seniors' decision-making for preventive measure adoption.</p></div><div><h3>Conclusion</h3><p>This study examined older adults' experiences with CoviD-19-related health literacy (access, comprehend, assess, and apply), as well as their preventative behaviours, barriers, and motivators. Future disease outbreak mitigation measures should consider the SEM approach in order to improve health communication and promote healthy behaviour.</p></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 2","pages":"Article 100014"},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950307824000110/pdfft?md5=c98af1c6e3700ada8f0f299ec7d5ed73&pid=1-s2.0-S2950307824000110-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140112622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between peripheral and respiratory muscle strength and gait speed in the elderly is not mediated by peripheral muscle blood flow 老年人外周肌力和呼吸肌力与步速之间的关系不受外周肌肉血流量的影响
Pub Date : 2024-03-02 DOI: 10.1016/j.aggp.2024.100017
Raphaela V Groehs, Ana Carla Carvalho, Weliton Nepomuceno Rodrigues, Isabela B Oliveira, Leticia Harada, Alexandra Passos Gaspar, Luciana Diniz Nagem Janot de Matos

Background

The aging process affects different systems, including the musculoskeletal and respiratory systems. Both systems seem to be interconnected in relation to functional capacity deterioration in the elderly. Therefore, this study aimed to evaluate the association between peripheral and respiratory muscle strength with gait speed and its possible mediation by leg muscle blood flow (LBF) in the elderly.

Methods

People aged over 65 years, of both sexes and clinically stable were evaluated. Gait speed was evaluated by the 4.6 m walking test. Maximal inspiratory pressure (MIP) and expiratory pressure (MEP) by manuvacuometry, Handgrip strength by a dynamometer (Jamar®) and LBF by venous occlusion plethysmography.

Results

We included 110 patients with mean age 76.9 ± 7.2 years, 56 (50.9 %) were women, 72 (67.9 %) were classified as frail by Fried criteria and 22 (20.0 %) reported the regular practice of exercise. Baseline mean values of MIP was 59.5 ± 23.8 and MEP 68.2 ± 23.8. The median gait speed was 0.88 m/s, handgrip strength 19.5 Kg/f and LBF 2.7 ml/min/100 ml. Further analysis showed a significant association between gait speed and handgrip strength with MIP (p = 0.005, p = 0.013, respectively). However, no mediation by LBF were found.

Conclusion

There is a strong association between gait speed and handgrip strength with MIP without mediation by LBF.

背景老化过程会影响不同的系统,包括肌肉骨骼系统和呼吸系统。这两个系统似乎与老年人功能衰退相互关联。因此,本研究旨在评估老年人外周肌和呼吸肌力量与步速之间的关系,以及腿部肌肉血流量(LBF)可能对其产生的调节作用。步速通过 4.6 米步行测试进行评估。结果我们共纳入了 110 名患者,平均年龄为 76.9 ± 7.2 岁,其中 56 人(50.9%)为女性,72 人(67.9%)根据弗里德标准被归类为体弱者,22 人(20.0%)表示经常锻炼。MIP 的基线平均值为 59.5 ± 23.8,MEP 为 68.2 ± 23.8。步速中位数为 0.88 米/秒,握力中位数为 19.5 公斤/英尺,肺活量中位数为 2.7 毫升/分钟/100 毫升。进一步分析表明,步速和手握力与 MIP 之间存在明显关联(分别为 p = 0.005 和 p = 0.013)。结论步速和握力与 MIP 之间存在密切联系,但不受 LBF 的影响。
{"title":"Association between peripheral and respiratory muscle strength and gait speed in the elderly is not mediated by peripheral muscle blood flow","authors":"Raphaela V Groehs,&nbsp;Ana Carla Carvalho,&nbsp;Weliton Nepomuceno Rodrigues,&nbsp;Isabela B Oliveira,&nbsp;Leticia Harada,&nbsp;Alexandra Passos Gaspar,&nbsp;Luciana Diniz Nagem Janot de Matos","doi":"10.1016/j.aggp.2024.100017","DOIUrl":"10.1016/j.aggp.2024.100017","url":null,"abstract":"<div><h3>Background</h3><p>The aging process affects different systems, including the musculoskeletal and respiratory systems. Both systems seem to be interconnected in relation to functional capacity deterioration in the elderly. Therefore, this study aimed to evaluate the association between peripheral and respiratory muscle strength with gait speed and its possible mediation by leg muscle blood flow (LBF) in the elderly.</p></div><div><h3>Methods</h3><p>People aged over 65 years, of both sexes and clinically stable were evaluated. Gait speed was evaluated by the 4.6 m walking test. Maximal inspiratory pressure (MIP) and expiratory pressure (MEP) by manuvacuometry, Handgrip strength by a dynamometer (Jamar®) and LBF by venous occlusion plethysmography.</p></div><div><h3>Results</h3><p>We included 110 patients with mean age 76.9 ± 7.2 years, 56 (50.9 %) were women, 72 (67.9 %) were classified as frail by Fried criteria and 22 (20.0 %) reported the regular practice of exercise. Baseline mean values of MIP was 59.5 ± 23.8 and MEP 68.2 ± 23.8. The median gait speed was 0.88 m/s, handgrip strength 19.5 Kg/f and LBF 2.7 ml/min/100 ml. Further analysis showed a significant association between gait speed and handgrip strength with MIP (<em>p</em> = 0.005, <em>p</em> = 0.013, respectively). However, no mediation by LBF were found.</p></div><div><h3>Conclusion</h3><p>There is a strong association between gait speed and handgrip strength with MIP without mediation by LBF.</p></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 2","pages":"Article 100017"},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950307824000146/pdfft?md5=b2541e5c2627e2a7829c24021bf8968c&pid=1-s2.0-S2950307824000146-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140092581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive intra-individual variability as an outcome or moderator of speed of processing training in aging adults with HIV-associated neurocognitive disorder: A secondary data analysis of a 2-year longitudinal randomized clinical trial 认知个体内部变异性是对患有艾滋病相关神经认知障碍的高龄成人进行处理速度训练的结果或调节因素:一项为期两年的纵向随机临床试验的二次数据分析
Pub Date : 2024-02-27 DOI: 10.1016/j.aggp.2024.100012
David E. Vance , Andres Azuero , Michael Vinikoor , Julie K. Schexnayder , Frank Puga , Benjamin Galatzan , Jun Y. Byun , Chunhong Xiao , Hathaichanok Phaowiriya , Dara L. James , Pariya L. Fazeli

Objective

Cognitive intra-individual variability (IIV), dispersion of cognitive performance across cognitive domains, indicates diminished cognitive control resulting from brain pathology or aging. For people with HIV-Associated Neurocognitive Disorder (HAND), cognitive IIV may interfere with and/or be improved by cognitive training. In this current secondary data analysis, we explored whether cognitive IIV functions as an outcome or moderator variable in speed of processing (SOP) training in middle-aged and older people living with HIV (PLWH).

Method

In this randomized clinical trial, 216 PLWH with HAND or borderline HAND were randomized to either: 1) 10 h of SOP training; 2) 20 h of SOP training, or 3) 10 h of Internet Navigation Control Training. Participants completed a seven-domain cognitive battery at baseline, posttest after training, and years 1 and 2 follow up; from this, the coefficient of variation (CoV) served as the cognitive IIV dispersion score. Participants also completed a gold-standard measure of SOP (i.e., Useful Field of View Test (UFOV®), a targeted cognitive outcomes of the SOP training paradigm) at each time point.

Results

Using linear mixed-effect models, no strong pattern of SOP training effects were detected on cognitive IIV. However, a three-way interaction tests between time, group, and baseline cognitive IIV CoV suggested potential moderation effects. Stratified analyses showed differential treatment effects between the lower cognitive IIV and higher cognitive IIV group.

Conclusions

Although SOP training did not improve cognitive IIV, cognitive IIV may be a modifier of SOP training. Implications for future research and other types of training are provided.

目标认知个体内变异性(IIV),即认知领域内认知表现的分散性,表明大脑病变或老化导致认知控制能力减弱。对于艾滋病毒相关神经认知障碍(HAND)患者来说,认知内变异性可能会干扰认知训练和/或通过认知训练得到改善。在目前的这项二手数据分析中,我们探讨了认知 IIV 在中老年艾滋病病毒感染者(PLWH)的处理速度(SOP)训练中是否起着结果或调节变量的作用:1)10 小时的 SOP 训练;2)20 小时的 SOP 训练;或 3)10 小时的互联网导航控制训练。受试者在基线、训练后测试以及第一和第二年的随访中完成了七域认知测试;变异系数(CoV)作为认知IIV离散度得分。受试者还在每个时间点完成了 SOP 的黄金标准测量(即有用视野测试 (UFOV®),这是 SOP 训练范式的目标认知结果)。然而,时间、组别和基线认知 IIV CoV 之间的三方交互检验表明可能存在调节作用。结论虽然 SOP 培训没有改善认知 IIV,但认知 IIV 可能是 SOP 培训的调节剂。本文对未来研究和其他类型的培训提供了启示。
{"title":"Cognitive intra-individual variability as an outcome or moderator of speed of processing training in aging adults with HIV-associated neurocognitive disorder: A secondary data analysis of a 2-year longitudinal randomized clinical trial","authors":"David E. Vance ,&nbsp;Andres Azuero ,&nbsp;Michael Vinikoor ,&nbsp;Julie K. Schexnayder ,&nbsp;Frank Puga ,&nbsp;Benjamin Galatzan ,&nbsp;Jun Y. Byun ,&nbsp;Chunhong Xiao ,&nbsp;Hathaichanok Phaowiriya ,&nbsp;Dara L. James ,&nbsp;Pariya L. Fazeli","doi":"10.1016/j.aggp.2024.100012","DOIUrl":"https://doi.org/10.1016/j.aggp.2024.100012","url":null,"abstract":"<div><h3>Objective</h3><p>Cognitive intra-individual variability (IIV), dispersion of cognitive performance across cognitive domains, indicates diminished cognitive control resulting from brain pathology or aging. For people with HIV-Associated Neurocognitive Disorder (HAND), cognitive IIV may interfere with and/or be improved by cognitive training. In this current secondary data analysis, we explored whether cognitive IIV functions as an outcome or moderator variable in speed of processing (SOP) training in middle-aged and older people living with HIV (PLWH).</p></div><div><h3>Method</h3><p>In this randomized clinical trial, 216 PLWH with HAND or borderline HAND were randomized to either: 1) 10 h of SOP training; 2) 20 h of SOP training, or 3) 10 h of Internet Navigation Control Training. Participants completed a seven-domain cognitive battery at baseline, posttest after training, and years 1 and 2 follow up; from this, the coefficient of variation (<em>CoV</em>) served as the cognitive IIV dispersion score. Participants also completed a gold-standard measure of SOP (i.e., Useful Field of View Test (UFOV®), a targeted cognitive outcomes of the SOP training paradigm) at each time point.</p></div><div><h3>Results</h3><p>Using linear mixed-effect models, no strong pattern of SOP training effects were detected on cognitive IIV. However, a three-way interaction tests between time, group, and baseline cognitive IIV <em>CoV</em> suggested potential moderation effects. Stratified analyses showed differential treatment effects between the lower cognitive IIV and higher cognitive IIV group.</p></div><div><h3>Conclusions</h3><p>Although SOP training did not improve cognitive IIV, cognitive IIV may be a modifier of SOP training. Implications for future research and other types of training are provided.</p></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 2","pages":"Article 100012"},"PeriodicalIF":0.0,"publicationDate":"2024-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950307824000092/pdfft?md5=19fced63480fc84103593ddec9272764&pid=1-s2.0-S2950307824000092-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140122294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations of depressive symptoms and instrumental activities of daily living decline by employment or participation in social activities among younger-older Japanese in the New Integrated Suburban Seniority Investigation (NISSIN) Project 新综合郊区老年调查(NISSIN)项目中日本年轻人-老年人因就业或参与社会活动而出现的抑郁症状与日常生活工具性活动减少之间的关系
Pub Date : 2024-02-25 DOI: 10.1016/j.aggp.2024.100013
Rika Taniguchi , Shigekazu Ukawa , Wenjing Zhao , Satoe Okabayashi , Takashi Kimura , Yifan Shan , Masahiko Ando , Kenji Wakai , Kazuyo Tsushita , Takashi Kawamura , Akiko Tamakoshi

Objectives

This study investigated the association between depressive symptoms and the instrumental activities of daily living (IADL) decline among physically and socially independent older people according to being employed or participating in social activities in a Japanese age-specific cohort.

Methods

We performed a prospective cohort study including 1,508 (716 men and 792 women) aged 64/65. Depressive symptoms were assessed at baseline (2000–2005). The change in IADL status was ascertained in the secondary survey when the participants reached 70 years of age. Multivariable odds ratios (ORs) and confidence intervals (CIs) of depressive symptoms for IADL decline were calculated using a logistic regression model adjusted for enroll year, sex, employment status, marital status, education, smoking status, alcohol consumption status, body mass index, walking status, daily sleep duration, and medical histories of cancer, cardio-cerebrovascular diseases, hypertension, and diabetes mellitus. We also formally tested for potential interaction effects by employment and participation in social activities.

Results

The OR of the presence of depressive symptoms and not employed was 3.25 (95% CI 1.57–6.75), compared to participants without depressive symptoms and employed, after adjusting for potential confounders. Compared to participants without depressive symptoms and with a high frequency of participation in social activities, participants with depressive symptoms and a low frequency of participation in social activities were associated with IADL decline (OR 2.45; 95% CI 1.23–4.90). However, we observed no evidence of an interaction effect by employment and participation in social activities.

Conclusions

This age-specific cohort study revealed that being employed or participating in social activities may prevent IADL decline among depressed older adults.

目的 本研究调查了日本特定年龄队列中,根据就业或参与社会活动情况,抑郁症状与身体独立和社会独立的老年人日常生活工具性活动(IADL)下降之间的关系。在基线(2000-2005 年)时对抑郁症状进行了评估。在参与者年满 70 岁时进行的二次调查中,我们确定了其 IADL 状况的变化。采用逻辑回归模型计算了抑郁症状与 IADL 下降的多变量几率比(ORs)和置信区间(CIs),并对入学年份、性别、就业状况、婚姻状况、教育程度、吸烟状况、饮酒状况、体重指数、步行状况、每日睡眠时间以及癌症、心脑血管疾病、高血压和糖尿病病史进行了调整。结果经调整潜在的混杂因素后,与无抑郁症状且有工作的参与者相比,有抑郁症状且无工作的参与者的OR值为3.25(95% CI为1.57-6.75)。与无抑郁症状且经常参加社交活动的参与者相比,有抑郁症状且经常参加社交活动的参与者的 IADL 下降率较低(OR 2.45;95% CI 1.23-4.90)。结论这项针对特定年龄段的队列研究显示,就业或参与社交活动可预防抑郁症老年人的 IADL 下降。
{"title":"Associations of depressive symptoms and instrumental activities of daily living decline by employment or participation in social activities among younger-older Japanese in the New Integrated Suburban Seniority Investigation (NISSIN) Project","authors":"Rika Taniguchi ,&nbsp;Shigekazu Ukawa ,&nbsp;Wenjing Zhao ,&nbsp;Satoe Okabayashi ,&nbsp;Takashi Kimura ,&nbsp;Yifan Shan ,&nbsp;Masahiko Ando ,&nbsp;Kenji Wakai ,&nbsp;Kazuyo Tsushita ,&nbsp;Takashi Kawamura ,&nbsp;Akiko Tamakoshi","doi":"10.1016/j.aggp.2024.100013","DOIUrl":"https://doi.org/10.1016/j.aggp.2024.100013","url":null,"abstract":"<div><h3>Objectives</h3><p>This study investigated the association between depressive symptoms and the instrumental activities of daily living (IADL) decline among physically and socially independent older people according to being employed or participating in social activities in a Japanese age-specific cohort.</p></div><div><h3>Methods</h3><p>We performed a prospective cohort study including 1,508 (716 men and 792 women) aged 64/65. Depressive symptoms were assessed at baseline (2000–2005). The change in IADL status was ascertained in the secondary survey when the participants reached 70 years of age. Multivariable odds ratios (ORs) and confidence intervals (CIs) of depressive symptoms for IADL decline were calculated using a logistic regression model adjusted for enroll year, sex, employment status, marital status, education, smoking status, alcohol consumption status, body mass index, walking status, daily sleep duration, and medical histories of cancer, cardio-cerebrovascular diseases, hypertension, and diabetes mellitus. We also formally tested for potential interaction effects by employment and participation in social activities.</p></div><div><h3>Results</h3><p>The OR of the presence of depressive symptoms and not employed was 3.25 (95% CI 1.57–6.75), compared to participants without depressive symptoms and employed, after adjusting for potential confounders. Compared to participants without depressive symptoms and with a high frequency of participation in social activities, participants with depressive symptoms and a low frequency of participation in social activities were associated with IADL decline (OR 2.45; 95% CI 1.23–4.90). However, we observed no evidence of an interaction effect by employment and participation in social activities.</p></div><div><h3>Conclusions</h3><p>This age-specific cohort study revealed that being employed or participating in social activities may prevent IADL decline among depressed older adults.</p></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 2","pages":"Article 100013"},"PeriodicalIF":0.0,"publicationDate":"2024-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950307824000109/pdfft?md5=b827cbe91fd4aebef854e2d03cfa524a&pid=1-s2.0-S2950307824000109-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140014447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Exploring the experiences of individuals with mild cognitive impairment during the COVID-19 pandemic: A qualitative study in Spanish hospitals” "探索轻度认知障碍患者在 COVID-19 大流行期间的经历:西班牙医院定性研究"
Pub Date : 2024-02-15 DOI: 10.1016/j.aggp.2024.100010
Victoria Pérez , Pablo De Lorena , Carmen Hermosilla-Grijalbo , Esther Domínguez , María Vigueiro-Mallán , Carmen Sarabia-Cobo

Background

The descriptive qualitative study was conducted in three Spanish hospitals during 2023, exploring the experiences of 34 individuals with Mild Cognitive Impairment (MCI) diagnosed during the COVID-19 pandemic.

Objective

To thoroughly investigate the experiences of participants with MCI in the context of the pandemic, identifying challenges, care guidelines, and support, while evaluating the emotional and social impact.

Methods

34 in-depth interviews were conducted, and purposive sampling was used to select participants with MCI. The COREQ recommendations were followed, and ethical approval was obtained.

Results

Five specific themes emerged: (1) Impact of Diagnosis in the Pandemic, (2) Daily Challenges and Pandemic, (3) Care Guidelines and Professional Support, (4) Social and Emotional Support in the Context of the Pandemic, and (5) Fear and Uncertainty. Participants expressed the need for an integrated approach and personalized care.

Conclusions

The results highlight the importance of clear communication and patient-centered care in managing MCI during the pandemic. The implementation of person-centered diagnosis and treatment processes is suggested. The need for future research evaluating effective coping strategies and the influence of fragmented care on disease progression is emphasized.

背景这项描述性定性研究于2023年在西班牙三家医院进行,探讨了34名在COVID-19大流行期间被诊断为轻度认知障碍(MCI)的患者的经历。目标深入调查MCI患者在大流行背景下的经历,确定面临的挑战、护理指南和支持,同时评估情感和社会影响。访谈遵循了 COREQ 的建议,并获得了伦理方面的批准。结果出现了五个特定主题:(1) 诊断对大流行病的影响,(2) 日常挑战与大流行病,(3) 护理指南与专业支持,(4) 大流行病背景下的社会与情感支持,以及 (5) 恐惧与不确定性。与会者表示需要综合方法和个性化护理。建议实施以人为本的诊断和治疗流程。强调今后有必要开展研究,评估有效的应对策略和分散护理对疾病进展的影响。
{"title":"“Exploring the experiences of individuals with mild cognitive impairment during the COVID-19 pandemic: A qualitative study in Spanish hospitals”","authors":"Victoria Pérez ,&nbsp;Pablo De Lorena ,&nbsp;Carmen Hermosilla-Grijalbo ,&nbsp;Esther Domínguez ,&nbsp;María Vigueiro-Mallán ,&nbsp;Carmen Sarabia-Cobo","doi":"10.1016/j.aggp.2024.100010","DOIUrl":"10.1016/j.aggp.2024.100010","url":null,"abstract":"<div><h3>Background</h3><p>The descriptive qualitative study was conducted in three Spanish hospitals during 2023, exploring the experiences of 34 individuals with Mild Cognitive Impairment (MCI) diagnosed during the COVID-19 pandemic.</p></div><div><h3>Objective</h3><p>To thoroughly investigate the experiences of participants with MCI in the context of the pandemic, identifying challenges, care guidelines, and support, while evaluating the emotional and social impact.</p></div><div><h3>Methods</h3><p>34 in-depth interviews were conducted, and purposive sampling was used to select participants with MCI. The COREQ recommendations were followed, and ethical approval was obtained.</p></div><div><h3>Results</h3><p>Five specific themes emerged: (1) Impact of Diagnosis in the Pandemic, (2) Daily Challenges and Pandemic, (3) Care Guidelines and Professional Support, (4) Social and Emotional Support in the Context of the Pandemic, and (5) Fear and Uncertainty. Participants expressed the need for an integrated approach and personalized care.</p></div><div><h3>Conclusions</h3><p>The results highlight the importance of clear communication and patient-centered care in managing MCI during the pandemic. The implementation of person-centered diagnosis and treatment processes is suggested. The need for future research evaluating effective coping strategies and the influence of fragmented care on disease progression is emphasized.</p></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 2","pages":"Article 100010"},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950307824000079/pdfft?md5=3d78f8098ab55114fe0ade8f30f664fd&pid=1-s2.0-S2950307824000079-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139886551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loneliness improved by either telephone or video communications in community-dwelling older adults 通过电话或视频通信改善居住在社区的老年人的孤独感
Pub Date : 2024-02-14 DOI: 10.1016/j.aggp.2024.100011
Justin T Mierzwicki, Joshua Kline, Brooke Schach, Lauren Vandenberg

Purpose/hypothesis

Loneliness and social isolation increase the risk of morbidity, and mortality. Various interventions, with and without use of technology, have improved older adults’ loneliness. The purpose of the study was to compare the impact of telephone versus video communications on perceived loneliness in older adults. It was hypothesized that video communication would result in improved outcomes compared to telephone communication.

Materials/methods

Eighteen hundred flyers were distributed among continuing care communities, meals on wheels, and snowball sampling was encouraged. Sixty-five potential participants responded, 44 were eligible to participate after application of inclusion and exclusion criteria. Participants were assigned into a telephone interaction group (n = 17), a video interaction group (n = 14), or control group (n = 13). Study duration was 8 weeks and consisted of once weekly 45 to 60-minute sessions. Pre-post-intervention outcome measures included UCLA Loneliness Scales (3 and 20-item), and the Social Frailty Scale (SFS). Data analyses were performed with One-Way ANOVA and Tukey's HSD post hoc tests.

Results

One-way ANOVA demonstrated statistically significant differences between groups (p=.003 UCLA 3, p<.001 UCLA 20, p<.001 SFS) with large effect sizes (eta2= 0.251 UCLA3, 0.410 UCLA20, 0.314 SFS). Tukey's HSD demonstrates statistically significant differences between intervention groups and the control group for each dependent variable (p<.011) but identified no significant differences between intervention groups for any dependent variables (p>.283).

Conclusion

Health care professionals can improve loneliness and social isolation through low-tech telephone and video-based communication interventions.

目的/假设孤独和社会隔离会增加发病和死亡的风险。使用或不使用技术的各种干预措施都能改善老年人的孤独感。本研究旨在比较电话和视频通讯对老年人孤独感的影响。材料/方法:在持续护理社区和轮椅上的就餐场所分发了 1800 份传单,并鼓励滚雪球式抽样。65 名潜在参与者做出了回应,其中 44 人符合纳入和排除标准。参与者被分配到电话互动组(17 人)、视频互动组(14 人)或对照组(13 人)。研究持续时间为 8 周,每周一次,每次 45 到 60 分钟。干预前和干预后的结果测量包括加州大学洛杉矶分校孤独感量表(3 项和 20 项)和社会脆弱性量表(SFS)。数据分析采用单向方差分析和 Tukey's HSD 后设检验。结果单向方差分析显示,组间差异具有统计学意义(p=.003 UCLA 3,p<.001 UCLA 20,p<.001 SFS),且效应大小较大(eta2= 0.251 UCLA3,0.410 UCLA20,0.314 SFS)。Tukey的HSD表明,干预组与对照组在每个因变量上都存在统计学上的显著差异(p< .011),但发现干预组之间在任何因变量上都没有显著差异(p> .283)。
{"title":"Loneliness improved by either telephone or video communications in community-dwelling older adults","authors":"Justin T Mierzwicki,&nbsp;Joshua Kline,&nbsp;Brooke Schach,&nbsp;Lauren Vandenberg","doi":"10.1016/j.aggp.2024.100011","DOIUrl":"10.1016/j.aggp.2024.100011","url":null,"abstract":"<div><h3>Purpose/hypothesis</h3><p>Loneliness and social isolation increase the risk of morbidity, and mortality. Various interventions, with and without use of technology, have improved older adults’ loneliness. The purpose of the study was to compare the impact of telephone versus video communications on perceived loneliness in older adults. It was hypothesized that video communication would result in improved outcomes compared to telephone communication.</p></div><div><h3>Materials/methods</h3><p>Eighteen hundred flyers were distributed among continuing care communities, meals on wheels, and snowball sampling was encouraged. Sixty-five potential participants responded, 44 were eligible to participate after application of inclusion and exclusion criteria. Participants were assigned into a telephone interaction group (<em>n</em> = 17), a video interaction group (<em>n</em> = 14), or control group (<em>n</em> = 13). Study duration was 8 weeks and consisted of once weekly 45 to 60-minute sessions. Pre-post-intervention outcome measures included UCLA Loneliness Scales (3 and 20-item), and the Social Frailty Scale (SFS). Data analyses were performed with One-Way ANOVA and Tukey's HSD post hoc tests.</p></div><div><h3>Results</h3><p>One-way ANOVA demonstrated statistically significant differences between groups (<em>p</em>=.003 UCLA 3, <em>p</em>&lt;.001 UCLA 20, <em>p</em>&lt;.001 SFS) with large effect sizes (eta<sup>2</sup>= 0.251 UCLA3, 0.410 UCLA20, 0.314 SFS). Tukey's HSD demonstrates statistically significant differences between intervention groups and the control group for each dependent variable (<em>p</em>&lt;.011) but identified no significant differences between intervention groups for any dependent variables (<em>p</em>&gt;.283).</p></div><div><h3>Conclusion</h3><p>Health care professionals can improve loneliness and social isolation through low-tech telephone and video-based communication interventions.</p></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 2","pages":"Article 100011"},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950307824000080/pdfft?md5=c39ab3956438fb2b4747271fe49abef5&pid=1-s2.0-S2950307824000080-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139892240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mortality from decreased food intake in older adults in nursing homes: A retrospective cohort study using electronic care record data 养老院老年人因食物摄入量减少而导致的死亡率:利用电子护理记录数据进行的回顾性队列研究
Pub Date : 2024-02-09 DOI: 10.1016/j.aggp.2024.100009
Kasumi Ikuta , Sakiko Fukui

Aim

To our knowledge, no studies have examined the risk of mortality in nursing homes using the routinely collected electronic care record information. We aimed to assess the risk of mortality using food intake data documented in electronic care records from Japanese nursing homes.

Methods

This academic–industry collaborative research included 814 older adults from five nursing homes in Japan. The study period was from January 1, 2016 to June 23, 2020. We used the rate of food intake data recorded by care workers in the electronic care records of the residents. We defined decreased food intake as the percentage decrease between admission and 90 days after admission into the nursing home, with cutoffs of 10%, 20%, and 30%.

Results

The number of older adults whose food intake decreased between admission and 90 days after admission was 114 (14.0%) at a 10% rate, 58 (7.1%) at a 20% rate, and 35 (4.3%) at a 30% rate. All three rates were significantly associated with mortality (10%: hazard ratio [HR] 2.02, 95% confidence interval [CI] 1.30–3.15; 20%: HR 3.03, 95% CI 1.68–5.47; and 30%: HR 4.50, 95% CI 2.15–9.44).

Conclusions

We found that the risk of mortality could conveniently be assessed from the food intake data collected routinely and comprehensively and documented in electronic care records in nursing homes. Our findings can be utilized in nursing homes, where medical staff are limited, to assess high-risk residents and to encourage a discussion regarding the management of end-of-life care.

目的据我们所知,还没有研究利用日常收集的电子护理记录信息对养老院的死亡风险进行过调查。我们旨在利用日本疗养院电子护理记录中记录的食物摄入数据评估死亡风险。研究时间为 2016 年 1 月 1 日至 2020 年 6 月 23 日。我们使用了护理人员在住院者电子护理记录中记录的食物摄入率数据。我们将食物摄入量减少定义为入住养老院后 90 天内食物摄入量减少的百分比,临界值为 10%、20% 和 30%。结果入住养老院后 90 天内食物摄入量减少的老年人数量为:10% 时 114 人(14.0%),20% 时 58 人(7.1%),30% 时 35 人(4.3%)。这三种比率均与死亡率有明显相关性(10%:危险比 [HR]2.02,95% 置信区间 [CI]1.30-3.15;20%:危险比 [HR]3.03,95% 置信区间 [CI]1.30-3.15):HR3.03,95% 置信区间 [CI] 1.68-5.47;以及 30%:结论我们发现,从养老院常规、全面收集并记录在电子护理记录中的食物摄入数据中可以方便地评估死亡风险。在医护人员有限的养老院中,我们的研究结果可用于评估高风险居民,并鼓励就临终关怀管理进行讨论。
{"title":"Mortality from decreased food intake in older adults in nursing homes: A retrospective cohort study using electronic care record data","authors":"Kasumi Ikuta ,&nbsp;Sakiko Fukui","doi":"10.1016/j.aggp.2024.100009","DOIUrl":"10.1016/j.aggp.2024.100009","url":null,"abstract":"<div><h3>Aim</h3><p>To our knowledge, no studies have examined the risk of mortality in nursing homes using the routinely collected electronic care record information. We aimed to assess the risk of mortality using food intake data documented in electronic care records from Japanese nursing homes.</p></div><div><h3>Methods</h3><p>This academic–industry collaborative research included 814 older adults from five nursing homes in Japan. The study period was from January 1, 2016 to June 23, 2020. We used the rate of food intake data recorded by care workers in the electronic care records of the residents. We defined decreased food intake as the percentage decrease between admission and 90 days after admission into the nursing home, with cutoffs of 10%, 20%, and 30%.</p></div><div><h3>Results</h3><p>The number of older adults whose food intake decreased between admission and 90 days after admission was 114 (14.0%) at a 10% rate, 58 (7.1%) at a 20% rate, and 35 (4.3%) at a 30% rate. All three rates were significantly associated with mortality (10%: hazard ratio [HR] 2.02, 95% confidence interval [CI] 1.30–3.15; 20%: HR 3.03, 95% CI 1.68–5.47; and 30%: HR 4.50, 95% CI 2.15–9.44).</p></div><div><h3>Conclusions</h3><p>We found that the risk of mortality could conveniently be assessed from the food intake data collected routinely and comprehensively and documented in electronic care records in nursing homes. Our findings can be utilized in nursing homes, where medical staff are limited, to assess high-risk residents and to encourage a discussion regarding the management of end-of-life care.</p></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 2","pages":"Article 100009"},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950307824000067/pdfft?md5=e331f47be51d711445712db23c348b3d&pid=1-s2.0-S2950307824000067-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139821412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of technology interventions in reducing social isolation and loneliness among community-dwelling older people: A mixed methods systematic review 技术干预在减少社区老年人社会隔离和孤独感方面的有效性:混合方法系统回顾
Pub Date : 2024-02-04 DOI: 10.1016/j.aggp.2024.100008
R.C. Ambagtsheer , K. Borg , L Townsin , M.A. Pinero de Plaza , L.M. O'Brien , R. Kunwar , M.T. Lawless

Objectives

This study reviewed technology-based interventions targeting social isolation and loneliness in community-dwelling older adults. Specific aims were to identify theoretical perspectives, assess intervention effectiveness, and identify barriers and enablers of these interventions.

Methods

A mixed methods systematic review of intervention studies was conducted, searching six databases (PubMed, PsychINFO, Cochrane Library, CINAHL, ACM and Embase). Peer-reviewed articles describing communicative technology-based intervention studies with qualitative, quantitative, mixed-method, or observational designs, conducted in community settings with older adults (aged ≥65 years), where social isolation and/or loneliness were key outcome measures, were included. The quality of the studies was assessed using the Mixed Methods Appraisal Tool (MMAT).

Results

Nineteen studies were included in the review. Theory integration was rare in these studies’ research designs. Most were small-scale pilot or feasibility studies, displaying diverse designs, small sample sizes, and variable MMAT-assessed quality. The studies highlighted significant barriers such as resource demands, participant health, literacy, and technical challenges.

Conclusion

Significant resource demands continue to impede technology-based interventions addressing social isolation and loneliness in older populations. Future study designs must adapt to overcome these challenges, tailoring approaches to marginalised and often frail communities these interventions aim to support.

目标本研究对针对社区老年人的社会隔离和孤独感的技术干预措施进行了综述。具体目的是确定理论视角、评估干预效果以及识别这些干预措施的障碍和促进因素。方法通过检索六个数据库(PubMed、PsychINFO、Cochrane Library、CINAHL、ACM 和 Embase),采用混合方法对干预研究进行了系统综述。同行评议的文章描述了基于交流技术的干预研究,这些研究采用定性、定量、混合方法或观察设计,在社区环境中针对老年人(年龄≥65 岁)进行,以社会隔离和/或孤独感为主要结果测量指标。研究质量采用混合方法评估工具(MMAT)进行评估。在这些研究的研究设计中,理论整合并不多见。大多数研究都是小规模的试点或可行性研究,显示出设计多样化、样本量小、MMAT 评估质量参差不齐等特点。这些研究强调了资源需求、参与者健康、文化水平和技术挑战等重大障碍。未来的研究设计必须调整以克服这些挑战,并针对这些干预措施所要支持的边缘化且往往虚弱的社区量身定制方法。
{"title":"The effectiveness of technology interventions in reducing social isolation and loneliness among community-dwelling older people: A mixed methods systematic review","authors":"R.C. Ambagtsheer ,&nbsp;K. Borg ,&nbsp;L Townsin ,&nbsp;M.A. Pinero de Plaza ,&nbsp;L.M. O'Brien ,&nbsp;R. Kunwar ,&nbsp;M.T. Lawless","doi":"10.1016/j.aggp.2024.100008","DOIUrl":"https://doi.org/10.1016/j.aggp.2024.100008","url":null,"abstract":"<div><h3>Objectives</h3><p>This study reviewed technology-based interventions targeting social isolation and loneliness in community-dwelling older adults. Specific aims were to identify theoretical perspectives, assess intervention effectiveness, and identify barriers and enablers of these interventions.</p></div><div><h3>Methods</h3><p>A mixed methods systematic review of intervention studies was conducted, searching six databases (PubMed, PsychINFO, Cochrane Library, CINAHL, ACM and Embase). Peer-reviewed articles describing communicative technology-based intervention studies with qualitative, quantitative, mixed-method, or observational designs, conducted in community settings with older adults (aged ≥65 years), where social isolation and/or loneliness were key outcome measures, were included. The quality of the studies was assessed using the Mixed Methods Appraisal Tool (MMAT).</p></div><div><h3>Results</h3><p>Nineteen studies were included in the review. Theory integration was rare in these studies’ research designs. Most were small-scale pilot or feasibility studies, displaying diverse designs, small sample sizes, and variable MMAT-assessed quality. The studies highlighted significant barriers such as resource demands, participant health, literacy, and technical challenges.</p></div><div><h3>Conclusion</h3><p>Significant resource demands continue to impede technology-based interventions addressing social isolation and loneliness in older populations. Future study designs must adapt to overcome these challenges, tailoring approaches to marginalised and often frail communities these interventions aim to support.</p></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"1 1","pages":"Article 100008"},"PeriodicalIF":0.0,"publicationDate":"2024-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2950307824000055/pdfft?md5=a10c74659d835197f6528823269a6976&pid=1-s2.0-S2950307824000055-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139715024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LONELINESS IMPROVED BY EITHER TELEPHONE OR VIDEO COMMUNICATIONS IN COMMUNITY-DWELLING OLDER ADULTS 通过电话或视频通信改善居住在社区的老年人的孤独感
Pub Date : 2024-02-01 DOI: 10.1016/j.aggp.2024.100011
Justin T. Mierzwicki, Joshua Kline, Brooke Schach, Lauren Vandenberg
{"title":"LONELINESS IMPROVED BY EITHER TELEPHONE OR VIDEO COMMUNICATIONS IN COMMUNITY-DWELLING OLDER ADULTS","authors":"Justin T. Mierzwicki, Joshua Kline, Brooke Schach, Lauren Vandenberg","doi":"10.1016/j.aggp.2024.100011","DOIUrl":"https://doi.org/10.1016/j.aggp.2024.100011","url":null,"abstract":"","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"85 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139832121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Archives of Gerontology and Geriatrics Plus
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1