In this study, chia seed mucilage (CSM) was extracted and used to prepare biodegradable film. The prepared film was modified with barberry extract (Ex) and tin oxide (SnO2) nanoparticles (NPs). According to the obtained results, barberry extract significantly increased the thickness of the film, while tin oxide nanoparticles affected the thickness very little. Adding nanoparticles to the film decreased both the tensile strength and flexibility of the film. Barberry extract increased the tensile strength and flexibility of the film. Barberry extract and tin oxide nanoparticles decreased the permeability to water vapor in the films. Barberry extract and tin oxide nanoparticles both increased the antioxidant property of the film. The addition of barberry extract and tin oxide nanoparticles significantly increased the antibacterial properties of the film against both Staphylococcus aureus and Escherichia coli bacteria. Physical connections and electrostatic interactions between composite components were confirmed by Fourier transform infrared (FTIR) spectra. The X-ray diffraction (XRD) results showed the positive effect of tin oxide nanoparticles in the formation of the crystal structure of the composite film. Additives of extract and nanoparticle increased the thermal stability of the film. The mucilage film with the highest percentage of tin oxide nanoparticles up to 50 % caused the photocatalytic degradation of methylene blue.
{"title":"Biodegradable photocatalytic film based on chia seed mucilage (xylose, glucose, and methyl glucuronic acid polysaccharides) containing barberry extract and SnO2 nanoparticles","authors":"Shirin Forouzan , Sajad Pirsa , Abolfazl Alirezalu","doi":"10.1016/j.carpta.2024.100592","DOIUrl":"10.1016/j.carpta.2024.100592","url":null,"abstract":"<div><div>In this study, chia seed mucilage (CSM) was extracted and used to prepare biodegradable film. The prepared film was modified with barberry extract (Ex) and tin oxide (SnO<sub>2</sub>) nanoparticles (NPs). According to the obtained results, barberry extract significantly increased the thickness of the film, while tin oxide nanoparticles affected the thickness very little. Adding nanoparticles to the film decreased both the tensile strength and flexibility of the film. Barberry extract increased the tensile strength and flexibility of the film. Barberry extract and tin oxide nanoparticles decreased the permeability to water vapor in the films. Barberry extract and tin oxide nanoparticles both increased the antioxidant property of the film. The addition of barberry extract and tin oxide nanoparticles significantly increased the antibacterial properties of the film against both <em>Staphylococcus aureus</em> and <em>Escherichia coli</em> bacteria. Physical connections and electrostatic interactions between composite components were confirmed by Fourier transform infrared (FTIR) spectra. The X-ray diffraction (XRD) results showed the positive effect of tin oxide nanoparticles in the formation of the crystal structure of the composite film. Additives of extract and nanoparticle increased the thermal stability of the film. The mucilage film with the highest percentage of tin oxide nanoparticles up to 50 % caused the photocatalytic degradation of methylene blue.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"8 ","pages":"Article 100592"},"PeriodicalIF":6.2,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The use of deep eutectic solvents (DESs) as environmentally friendly alternatives to traditional volatile organic solvents has attracted significant attention in the industrial sector. In this study, molecular dynamics simulations were utilized to examine the physicochemical and structural characteristics of novel DESs—specifically DES1, DES2, and DES3—comprising methyl-β-cyclodextrin (MBCD) mixed with formic acid (FA), propionic acid (PA), and acetic acid (AA), respectively, in a 1:3 molar ratio. Structural analysis, as revealed by the combined distribution function and radial distribution function, indicated that the dominant interactions within the DESs occur between the hydroxyl hydrogen of the acids and the hydroxyl oxygen of MBCD, as well as between the hydroxyl hydrogen of MBCD and the carbonyl oxygen of the acids. Furthermore, it was observed that MBCD forms more hydrogen bonds and non-bonded interactions with PA than with FA or AA. As a result, PA exhibits a lower self-diffusion coefficient compared to FA and AA. The findings also demonstrate that the influence of the acid type on the density and isothermal compressibility of the DESs follows the order: DES2 > DES1 > DES3 for density and DES3 > DES2 > DES1 for compressibility. Overall, this study provides valuable insights into the behavior of novel MBCD-based DESs, offering predictive insights for their potential applications in extraction processes.
深共晶溶剂（DES）作为传统挥发性有机溶剂的环保型替代品，在工业领域备受关注。本研究利用分子动力学模拟研究了新型 DES 的物理化学和结构特征，特别是 DES1、DES2 和 DES3，它们分别由甲基-β-环糊精（MBCD）与甲酸（FA）、丙酸（PA）和乙酸（AA）以 1:3 的摩尔比混合而成。综合分布函数和径向分布函数显示的结构分析表明，DES 内部的主要相互作用发生在酸的羟基氢和 MBCD 的羟基氧之间，以及 MBCD 的羟基氢和酸的羰基氧之间。此外，还观察到 MBCD 与 PA 形成的氢键和非键相互作用多于与 FA 或 AA 形成的氢键和非键相互作用。因此，与 FA 和 AA 相比，PA 的自扩散系数较低。研究结果还表明，酸类型对 DES 的密度和等温压缩性的影响遵循以下顺序：密度为 DES2 > DES1 > DES3，压缩性为 DES3 > DES2 > DES1。总之，这项研究为了解基于 MBCD 的新型 DES 的行为提供了宝贵的见解，为其在萃取过程中的潜在应用提供了预测性的见解。
{"title":"A computational probe into the physicochemical properties of cyclodextrin-based deep eutectic solvents for extraction processes","authors":"Parisa Jahanbakhsh-Bonab , Zahra Khoshnazar , Jaber Jahanbin Sardroodi , Ehsan Heidaryan","doi":"10.1016/j.carpta.2024.100596","DOIUrl":"10.1016/j.carpta.2024.100596","url":null,"abstract":"<div><div>The use of deep eutectic solvents (DESs) as environmentally friendly alternatives to traditional volatile organic solvents has attracted significant attention in the industrial sector. In this study, molecular dynamics simulations were utilized to examine the physicochemical and structural characteristics of novel DESs—specifically DES1, DES2, and DES3—comprising methyl-β-cyclodextrin (MBCD) mixed with formic acid (FA), propionic acid (PA), and acetic acid (AA), respectively, in a 1:3 molar ratio. Structural analysis, as revealed by the combined distribution function and radial distribution function, indicated that the dominant interactions within the DESs occur between the hydroxyl hydrogen of the acids and the hydroxyl oxygen of MBCD, as well as between the hydroxyl hydrogen of MBCD and the carbonyl oxygen of the acids. Furthermore, it was observed that MBCD forms more hydrogen bonds and non-bonded interactions with PA than with FA or AA. As a result, PA exhibits a lower self-diffusion coefficient compared to FA and AA. The findings also demonstrate that the influence of the acid type on the density and isothermal compressibility of the DESs follows the order: DES2 > DES1 > DES3 for density and DES3 > DES2 > DES1 for compressibility. Overall, this study provides valuable insights into the behavior of novel MBCD-based DESs, offering predictive insights for their potential applications in extraction processes.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"8 ","pages":"Article 100596"},"PeriodicalIF":6.2,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-19DOI: 10.1016/j.carpta.2024.100590
Andriani Tsompou , Peter Falkman , Ann Terry , Vitaly Kocherbitov
The cotton fabric consists of cellulose arranged in a complex structure with multiple levels of organization at different length scales. Understanding this structure and its interactions with water and oil is essential for developing efficient and environmentally friendly methods of cotton washing. In this study, the structure of raw cotton fabric cellulose and the effects of water and oil were examined across a broad range of length scales using spatially resolved synchrotron small-angle X-ray scattering (SAXS) and auxiliary techniques.
Water was observed to penetrate the cotton fabric and interact across nearly all length scales. Although a certain amount of the material was not affected by water as seen by intact distance between microfibrils, fractal analysis of the scattering data indicated a loosening of the microfibril arrangement after contact with water. This process was hindered if the material had been pre-treated with oil and was not seen after subsequent washing with water or surfactant solution. Analyzing spatially resolved SAXS data using a bi-sinusoidal model and 2D maps of the oil-to-cotton ratio facilitates understanding the structure of the material and its interactions with oil on the molecular, nano and macrolevels.
棉织物由纤维素组成，其结构复杂，在不同长度尺度上具有多层次的组织结构。了解这种结构及其与水和油的相互作用对于开发高效、环保的棉布洗涤方法至关重要。在这项研究中，利用空间分辨同步加速器小角 X 射线散射（SAXS）和辅助技术，在广泛的长度尺度范围内研究了原棉织物纤维素的结构以及水和油的影响。虽然从微纤维之间的完整距离可以看出，一定量的材料不受水的影响，但对散射数据的分形分析表明，微纤维的排列在与水接触后会变得松散。如果材料预先用油处理过，这一过程就会受到阻碍，而且在随后用水或表面活性剂溶液清洗后也不会出现这种情况。使用双正弦曲线模型和油棉比二维图分析空间分辨 SAXS 数据有助于了解材料的结构及其与油在分子、纳米和宏观层面上的相互作用。
{"title":"A structural investigation on the interactions of cotton fabric cellulose with olive oil and water","authors":"Andriani Tsompou , Peter Falkman , Ann Terry , Vitaly Kocherbitov","doi":"10.1016/j.carpta.2024.100590","DOIUrl":"10.1016/j.carpta.2024.100590","url":null,"abstract":"<div><div>The cotton fabric consists of cellulose arranged in a complex structure with multiple levels of organization at different length scales. Understanding this structure and its interactions with water and oil is essential for developing efficient and environmentally friendly methods of cotton washing. In this study, the structure of raw cotton fabric cellulose and the effects of water and oil were examined across a broad range of length scales using spatially resolved synchrotron small-angle X-ray scattering (SAXS) and auxiliary techniques.</div><div>Water was observed to penetrate the cotton fabric and interact across nearly all length scales. Although a certain amount of the material was not affected by water as seen by intact distance between microfibrils, fractal analysis of the scattering data indicated a loosening of the microfibril arrangement after contact with water. This process was hindered if the material had been pre-treated with oil and was not seen after subsequent washing with water or surfactant solution. Analyzing spatially resolved SAXS data using a bi-sinusoidal model and 2D maps of the oil-to-cotton ratio facilitates understanding the structure of the material and its interactions with oil on the molecular, nano and macrolevels.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"8 ","pages":"Article 100590"},"PeriodicalIF":6.2,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142653955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clean drinking water has been a challenge due to the pollution from industrialization, urbanization, the growing global population, and lack of infrastructure. Textile industry waste has become a major problem due to wastewater that contains dyes commonly discharged into the water bodies. Wastewater-containing dye should be treated to avoid undesired environmental effects. Among the various water treatment methods, photocatalysis has been getting growing attention in mitigating water pollution issues, particularly in removing organic contaminants (such as organic dyes) due to their good efficiency, low cost, and environmental friendliness. Organic-inorganic composites such as combinations of cellulose and semiconductors can produce unique functional hybrid materials with tailored characteristics. Cellulose has been used as a carrier material due to its superfine network structure, reactive surface groups, and good compatibility with metal oxides. In addition to increasing the catalyst surface area, it improves the photocatalytic effectiveness of nanocomposites by acting as electron acceptors and transporters resulting in a better charge carrier separation. Therefore, cellulose-based photocatalytic membranes are environmentally friendly, fully biodegradable, and biocompatible with efficient applications in wastewater management for the degradation of organic dyes. In this review work, the applications of cellulose-based photocatalytic membranes for the removal of cationic and anionic organic dyes have been reviewed.
{"title":"Cellulose-based photocatalytic membranes for dye degradation: A review","authors":"Medhanit Tefera Yifira , Anteneh Kindu Mersha , Gebrehiwot Gebreslassie , Kebede Nigussie Mekonnen","doi":"10.1016/j.carpta.2024.100589","DOIUrl":"10.1016/j.carpta.2024.100589","url":null,"abstract":"<div><div>Clean drinking water has been a challenge due to the pollution from industrialization, urbanization, the growing global population, and lack of infrastructure. Textile industry waste has become a major problem due to wastewater that contains dyes commonly discharged into the water bodies. Wastewater-containing dye should be treated to avoid undesired environmental effects. Among the various water treatment methods, photocatalysis has been getting growing attention in mitigating water pollution issues, particularly in removing organic contaminants (such as organic dyes) due to their good efficiency, low cost, and environmental friendliness. Organic-inorganic composites such as combinations of cellulose and semiconductors can produce unique functional hybrid materials with tailored characteristics. Cellulose has been used as a carrier material due to its superfine network structure, reactive surface groups, and good compatibility with metal oxides. In addition to increasing the catalyst surface area, it improves the photocatalytic effectiveness of nanocomposites by acting as electron acceptors and transporters resulting in a better charge carrier separation. Therefore, cellulose-based photocatalytic membranes are environmentally friendly, fully biodegradable, and biocompatible with efficient applications in wastewater management for the degradation of organic dyes. In this review work, the applications of cellulose-based photocatalytic membranes for the removal of cationic and anionic organic dyes have been reviewed.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"8 ","pages":"Article 100589"},"PeriodicalIF":6.2,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-15DOI: 10.1016/j.carpta.2024.100588
A.E. Swathe Sriee , Vijayalakshmi Shankar
Major environmental and health effects arise from the presence of heavy metals in water, including lead (Pb²⁺), mercury (Hg²⁺), chromium (Cr⁶⁺), cadmium (Cd²⁺), and arsenic (As³⁺), which contribute significantly to water pollution and pose severe risks to ecosystems and human health. This study demonstrates the fabrication of 3D printed self-regenerative functional living materials, a fungi, by using mixture of sodium alginate and hyaluronic acid hydrogel as absorbents to remove the heavy metals from the environment. Bioprinting has emerged as a transformative technology for fabricating complex biological constructs. The bioprinting experiments, conducted with optimized parameters, revealed the viscoelastic behavior of the hydrogel, suitable for 3D bioprinting applications. MicroCT analysis indicated that the hydrogel's porosity and structural properties support fungal growth in a controlled three-dimensional setting. Microscopic analyses, including phase contrast microscopy, FESEM, and HRTEM, provided insights into the cellular morphology of the bioprinted constructs. Cell viability was assessed using flow cytometry with FDA and PI staining, showing a significant population of live cells, affirming the biocompatibility of the hydrogel. Additionally, the study explored the hydrogel's potential for heavy metal removal from water samples. Multi-element standard solutions containing Copper (Cu²⁺), Cadmium (Cd²⁺), Nickel (Ni²⁺), Cobalt (Co²⁺), and Ferrous (Fe³⁺) ions at different concentrations were incubated with hydrogel patches embedded with Aspergillus flavus. Atomic absorption spectrophotometry analysis showed rapid initial removal rates of metal ions, with maximum removal efficiency achieved around the 12th hour. Comparisons with a control hydrogel without the fungal strain demonstrated significantly enhanced removal efficiency due to the presence of Aspergillus flavus. This study highlights the dual functionality of sodium alginate with hyaluronic acid -based hydrogels for bioprinting fungi and for environmental remediation of heavy metals, offering promising applications in environmental cleanup.
水中重金属（包括铅（Pb²⁺）、汞（Hg²⁺）、铬（Cr⁶⁺）、镉（Cd²⁺）和砷（As³⁺））对环境和健康产生重大影响，严重加剧了水污染，对生态系统和人类健康构成严重威胁。本研究展示了利用海藻酸钠和透明质酸水凝胶的混合物作为吸附剂，制造三维打印的自再生功能性活体材料--真菌，以去除环境中的重金属。生物打印已成为制造复杂生物构造物的变革性技术。采用优化参数进行的生物打印实验揭示了水凝胶的粘弹性行为，适合三维生物打印应用。显微 CT 分析表明，水凝胶的孔隙率和结构特性支持真菌在受控三维环境中生长。相衬显微镜、FESEM 和 HRTEM 等显微分析有助于深入了解生物打印构建体的细胞形态。使用 FDA 和 PI 染色流式细胞仪对细胞存活率进行了评估，结果显示有大量的活细胞，这肯定了水凝胶的生物相容性。此外，研究还探讨了水凝胶去除水样中重金属的潜力。将含有不同浓度的铜（Cu²⁺）、镉（Cd²⁺）、镍（Ni²⁺）、钴（Co²⁺）和亚铁（Fe³⁺）离子的多元素标准溶液与嵌入黄曲霉的水凝胶贴片一起培养。原子吸收分光光度法分析表明，金属离子的初始去除率很快，在第 12 小时左右达到最高去除效率。与不含真菌菌株的对照水凝胶相比，由于黄曲霉的存在，去除效率明显提高。这项研究强调了海藻酸钠与透明质酸水凝胶的双重功能，既可用于真菌的生物打印，也可用于重金属的环境修复，在环境净化方面具有广阔的应用前景。
{"title":"Three-dimensional bioprinted materials in alginate-hyaluronic acid complex based hydrogel based bio-ink as absorbents for heavy metal ions removal","authors":"A.E. Swathe Sriee , Vijayalakshmi Shankar","doi":"10.1016/j.carpta.2024.100588","DOIUrl":"10.1016/j.carpta.2024.100588","url":null,"abstract":"<div><div>Major environmental and health effects arise from the presence of heavy metals in water, including lead (Pb²⁺), mercury (Hg²⁺), chromium (Cr⁶⁺), cadmium (Cd²⁺), and arsenic (As³⁺), which contribute significantly to water pollution and pose severe risks to ecosystems and human health. This study demonstrates the fabrication of 3D printed self-regenerative functional living materials, a fungi, by using mixture of sodium alginate and hyaluronic acid hydrogel as absorbents to remove the heavy metals from the environment. Bioprinting has emerged as a transformative technology for fabricating complex biological constructs. The bioprinting experiments, conducted with optimized parameters, revealed the viscoelastic behavior of the hydrogel, suitable for 3D bioprinting applications. MicroCT analysis indicated that the hydrogel's porosity and structural properties support fungal growth in a controlled three-dimensional setting. Microscopic analyses, including phase contrast microscopy, FESEM, and HRTEM, provided insights into the cellular morphology of the bioprinted constructs. Cell viability was assessed using flow cytometry with FDA and PI staining, showing a significant population of live cells, affirming the biocompatibility of the hydrogel. Additionally, the study explored the hydrogel's potential for heavy metal removal from water samples. Multi-element standard solutions containing Copper (Cu²⁺), Cadmium (Cd²⁺), Nickel (Ni²⁺), Cobalt (Co²⁺), and Ferrous (Fe³⁺) ions at different concentrations were incubated with hydrogel patches embedded with <em>Aspergillus flavus</em>. Atomic absorption spectrophotometry analysis showed rapid initial removal rates of metal ions, with maximum removal efficiency achieved around the 12th hour. Comparisons with a control hydrogel without the fungal strain demonstrated significantly enhanced removal efficiency due to the presence of <em>Aspergillus flavus</em>. This study highlights the dual functionality of sodium alginate with hyaluronic acid -based hydrogels for bioprinting fungi and for environmental remediation of heavy metals, offering promising applications in environmental cleanup.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"8 ","pages":"Article 100588"},"PeriodicalIF":6.2,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-11DOI: 10.1016/j.carpta.2024.100585
Yufei Nan , Diego Gomez-Maldonado , Kailong Zhang , Haishun Du , Daniel C. Whitehead , Mi Li , Xinyu Zhang , Maria Soledad Peresin
A stable 2,2,6,6-tetramethylpiperidine-1-yl)oxyl (TEMPO)-oxidized cellulose nanofibril (TCNF)/graphene oxide (GO)/polyethylenimine (PEI) composite hydrogel was synthesized by self-assembly instead of chemical crosslinking. Their chemical, morphology, surface, and mechanical properties were characterized and adsorption behavior for methyl blue (–) was systematically investigated in terms of the optimal GO content, pH effect, kinetics, and isotherm models. Additionally, to assess the adsorption capability of the TCNF/GO/PEI hydrogel for various contaminants, its effectiveness was also tested for methylene blue (+), Cu (II), and soybean oils. The maximum adsorption capability for the methyl blue (−) dyes increased from 3125 to 3962 mg/g when 13.3 % of GO was added. The adsorption capability for Cu (II) and soybean oils rose from 205.3 to 218.5 and 2.1 to 7.2 mg/g, respectively. The adsorption capability of optimized TCNF/GO/PEI hydrogel for a variety of contaminants was improved overall based on the increase of surface area, electrostatic interactions, and hydrophobic domains. Moreover, adding GO did not impact the adsorption mechanism but increased the external diffusion rate in the intraparticle diffusion model. This work provides a self-assembling route to TCNF/GO/PEI hydrogels with great potential for the removal of multiple water pollutants.
{"title":"Polyethylenimine functionalized graphene oxide and cellulose nanofibril composite hydrogels: Synthesis, characterization and water pollutants adsorption","authors":"Yufei Nan , Diego Gomez-Maldonado , Kailong Zhang , Haishun Du , Daniel C. Whitehead , Mi Li , Xinyu Zhang , Maria Soledad Peresin","doi":"10.1016/j.carpta.2024.100585","DOIUrl":"10.1016/j.carpta.2024.100585","url":null,"abstract":"<div><div>A stable 2,2,6,6-tetramethylpiperidine-1-yl)oxyl (TEMPO)-oxidized cellulose nanofibril (TCNF)/graphene oxide (GO)/polyethylenimine (PEI) composite hydrogel was synthesized by self-assembly instead of chemical crosslinking. Their chemical, morphology, surface, and mechanical properties were characterized and adsorption behavior for methyl blue (–) was systematically investigated in terms of the optimal GO content, pH effect, kinetics, and isotherm models. Additionally, to assess the adsorption capability of the TCNF/GO/PEI hydrogel for various contaminants, its effectiveness was also tested for methylene blue (+), Cu (II), and soybean oils. The maximum adsorption capability for the methyl blue (−) dyes increased from 3125 to 3962 mg/g when 13.3 % of GO was added. The adsorption capability for Cu (II) and soybean oils rose from 205.3 to 218.5 and 2.1 to 7.2 mg/g, respectively. The adsorption capability of optimized TCNF/GO/PEI hydrogel for a variety of contaminants was improved overall based on the increase of surface area, electrostatic interactions, and hydrophobic domains. Moreover, adding GO did not impact the adsorption mechanism but increased the external diffusion rate in the intraparticle diffusion model. This work provides a self-assembling route to TCNF/GO/PEI hydrogels with great potential for the removal of multiple water pollutants.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"8 ","pages":"Article 100585"},"PeriodicalIF":6.2,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-10DOI: 10.1016/j.carpta.2024.100587
Izabela Dziedzic , Kamil Dydek , Jakub Trzciński , Anna Boczkowska , Alona Voronkina , Teofil Jesionowski , Hermann Ehrlich
This study represents the first creation and characterization of a 3D chitin/chitosan composite scaffold derived from the naturally pre-structured skeleton of the cultivated marine demosponge Aplysina aerophoba, aiming to preserve the intricate architecture of the unique tube-like chitin while incorporating chitosan layers. Advanced staining methods, including the use of iodine and Cibacron Brilliant Red (CBR), were employed to distinguish these polysaccharides. ATR-FTIR spectroscopy confirmed the system's structural integrity and identified the optimal chitin/chitosan balance, achieved after 60-minute treatment in 38 % NaOH at 95 °C. Fluorescent microscopy using fluorescein isothiocyanate (FITC) effectively confirmed the presence of chitosan layers in the created chitin/chitosan scaffolds. Scanning electron microscopy analysis further elucidated significant morphological distinctions, where chitin fibers displayed a smooth, uniform surface, contrasting with the ragged and irregular texture of chitosan-containing fibers, indicating significant surface modifications. Zeta potential measurements confirmed the partial transformation of chitin into chitosan. The dual-layer configuration, consisting of a resilient chitin core and a versatile chitosan exterior, not only provides structural support, but also enhances the scaffold's functionality for potential technological and biomedical applications. The preferential metallization of the chitosan phase by copper nanoparticles in the created 3D chitin/chitosan composite opens the way to the potential use of such scaffolds in catalysis.
{"title":"Creation of 3D chitin/chitosan composite scaffold from naturally pre-structured verongiid sponge skeleton","authors":"Izabela Dziedzic , Kamil Dydek , Jakub Trzciński , Anna Boczkowska , Alona Voronkina , Teofil Jesionowski , Hermann Ehrlich","doi":"10.1016/j.carpta.2024.100587","DOIUrl":"10.1016/j.carpta.2024.100587","url":null,"abstract":"<div><div>This study represents the first creation and characterization of a 3D chitin/chitosan composite scaffold derived from the naturally pre-structured skeleton of the cultivated marine demosponge <em>Aplysina aerophoba</em>, aiming to preserve the intricate architecture of the unique tube-like chitin while incorporating chitosan layers. Advanced staining methods, including the use of iodine and Cibacron Brilliant Red (CBR), were employed to distinguish these polysaccharides. ATR-FTIR spectroscopy confirmed the system's structural integrity and identified the optimal chitin/chitosan balance, achieved after 60-minute treatment in 38 % NaOH at 95 °C. Fluorescent microscopy using fluorescein isothiocyanate (FITC) effectively confirmed the presence of chitosan layers in the created chitin/chitosan scaffolds. Scanning electron microscopy analysis further elucidated significant morphological distinctions, where chitin fibers displayed a smooth, uniform surface, contrasting with the ragged and irregular texture of chitosan-containing fibers, indicating significant surface modifications. Zeta potential measurements confirmed the partial transformation of chitin into chitosan. The dual-layer configuration, consisting of a resilient chitin core and a versatile chitosan exterior, not only provides structural support, but also enhances the scaffold's functionality for potential technological and biomedical applications. The preferential metallization of the chitosan phase by copper nanoparticles in the created 3D chitin/chitosan composite opens the way to the potential use of such scaffolds in catalysis.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"8 ","pages":"Article 100587"},"PeriodicalIF":6.2,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142432108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-10DOI: 10.1016/j.carpta.2024.100584
Qianqian Zhao , Datao Hu , Ting Wang , Hanchao Zhou , Jinli Gao , Ke Wang , Daqing Zhao , Leping Liang
In this study, chlorogenic acid-modified hyaluronic acid (HA-CGA) and phenylboric acid-modified ciprofloxacin (Cip-BPA) were synthesized and their structures were analyzed by 1HNMR and 13CNMR. Following, a dynamic borate and hydrogen bond crosslinked HCCB hydrogel was prepared by mixing HA-CGA and Cip-BPA solution. Its properties and gel formation mechanism were studied by means of ratio optimization, scanning electron microscopy, rheology, 11B-NMR and temperature-changing infrared spectroscopy. The basic properties and bioactivity of HCCB hydrogel were investigated by in vitro antibacterial experiment, in vitro anti-inflammatory oxidation experiment and biocompatibility test. We found that borate ester bond and hydrogen bond are important driving forces for the formation of HCCB hydrogels, and when the molar ratio of chlorogenic acid in HA-CGA and phenylboronic acid in Cip-BPA is 2:1, the properties of HCCB hydrogels formed are the best. It has excellent antibacterial properties, anti-inflammatory and antioxidant properties, good biocompatibility and pH/ROS response. The successful preparation of the gel and its excellent properties indicate that it has great potential in the treatment of some inflammation treatment.
{"title":"An injectable supramolecular antimicrobial hydrogel based on hyaluronic acid with dynamic borate bond and hydrogen bond crosslinking for sinusitis treatment","authors":"Qianqian Zhao , Datao Hu , Ting Wang , Hanchao Zhou , Jinli Gao , Ke Wang , Daqing Zhao , Leping Liang","doi":"10.1016/j.carpta.2024.100584","DOIUrl":"10.1016/j.carpta.2024.100584","url":null,"abstract":"<div><div>In this study, chlorogenic acid-modified hyaluronic acid (HA-CGA) and phenylboric acid-modified ciprofloxacin (Cip-BPA) were synthesized and their structures were analyzed by <sup>1</sup>H<img>NMR and <sup>13</sup>C<img>NMR. Following, a dynamic borate and hydrogen bond crosslinked HCCB hydrogel was prepared by mixing HA-CGA and Cip-BPA solution. Its properties and gel formation mechanism were studied by means of ratio optimization, scanning electron microscopy, rheology, <sup>11</sup>B-NMR and temperature-changing infrared spectroscopy. The basic properties and bioactivity of HCCB hydrogel were investigated by in vitro antibacterial experiment, in vitro anti-inflammatory oxidation experiment and biocompatibility test. We found that borate ester bond and hydrogen bond are important driving forces for the formation of HCCB hydrogels, and when the molar ratio of chlorogenic acid in HA-CGA and phenylboronic acid in Cip-BPA is 2:1, the properties of HCCB hydrogels formed are the best. It has excellent antibacterial properties, anti-inflammatory and antioxidant properties, good biocompatibility and pH/ROS response. The successful preparation of the gel and its excellent properties indicate that it has great potential in the treatment of some inflammation treatment.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"8 ","pages":"Article 100584"},"PeriodicalIF":6.2,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-10DOI: 10.1016/j.carpta.2024.100586
Gergely Kali , Alexander H. Mayer , Dennis To , Martyna Truszkowska , Raphael Plangger , Markus Gallei , Andreas Bernkop-Schnürch
Background and Aim
Polyrotaxanes are molecular necklaces composed of polymers, threaded macrocycles, and bulky stopper molecules to inhibit the decomposition of the first two. These supramolecular assemblies are promising active ingredients for treating lysosomal storage disorders. This study aimed to synthesize such polyrotaxanes with a novel, simple method, resulting in high threading efficacy, enhanced cellular uptake, and intracellular cyclodextrin (CD) release.
Methods
In this study, we developed two novel poly(ethylene glycol) (PEG) based polyrotaxanes, with threaded α-cyclodextrin (α-CD) or its mixture with 2-hydroxypropyl-α-CD (HP-α-CD) and glutathione sensitive disulfide connected stopper molecules. The structure and composition of these polyrotaxanes were determined by 1H NMR spectroscopy and gel permeation chromatography, while the cellular uptake was investigated by flow cytometry and confocal microscopy.
Results
High threading efficacy, as well as molar mass of 17.9 and 13.1 kDa, was found for the polymeric supramolecules with threaded α-CD and α-CD/HP-α-CD, respectively. Glutathion-triggered reductive removal of the stopper molecules showed potential decomposition of these polyrotaxanes in target cells. Flow cytometry revealed an up to 52-fold enhancement in cellular uptake of α- and HP-α-CD by the polyrotaxanes compared to free CD, which was also visualized by confocal microscopy.
Conclusion and scope of application
Polyrotaxanes based on α-CD and its derivative were tested in vitro for application in the treatment of lysosomal storage disease for the first time. Based on these results, polyrotaxanes with disulfide stopper molecules might be promising supramolecular excipients for cellular delivery of α-CDs.
{"title":"Disulfide stoppered polyrotaxanes with enhanced cellular uptake and intracellular cyclodextrin release","authors":"Gergely Kali , Alexander H. Mayer , Dennis To , Martyna Truszkowska , Raphael Plangger , Markus Gallei , Andreas Bernkop-Schnürch","doi":"10.1016/j.carpta.2024.100586","DOIUrl":"10.1016/j.carpta.2024.100586","url":null,"abstract":"<div><h3>Background and Aim</h3><div>Polyrotaxanes are molecular necklaces composed of polymers, threaded macrocycles, and bulky stopper molecules to inhibit the decomposition of the first two. These supramolecular assemblies are promising active ingredients for treating lysosomal storage disorders. This study aimed to synthesize such polyrotaxanes with a novel, simple method, resulting in high threading efficacy, enhanced cellular uptake, and intracellular cyclodextrin (CD) release.</div></div><div><h3>Methods</h3><div>In this study, we developed two novel poly(ethylene glycol) (PEG) based polyrotaxanes, with threaded α-cyclodextrin (α-CD) or its mixture with 2-hydroxypropyl-α-CD (HP-α-CD) and glutathione sensitive disulfide connected stopper molecules. The structure and composition of these polyrotaxanes were determined by <sup>1</sup>H NMR spectroscopy and gel permeation chromatography, while the cellular uptake was investigated by flow cytometry and confocal microscopy.</div></div><div><h3>Results</h3><div>High threading efficacy, as well as molar mass of 17.9 and 13.1 kDa, was found for the polymeric supramolecules with threaded α-CD and α-CD/HP-α-CD, respectively. Glutathion-triggered reductive removal of the stopper molecules showed potential decomposition of these polyrotaxanes in target cells. Flow cytometry revealed an up to 52-fold enhancement in cellular uptake of α- and HP-α-CD by the polyrotaxanes compared to free CD, which was also visualized by confocal microscopy.</div></div><div><h3>Conclusion and scope of application</h3><div>Polyrotaxanes based on α-CD and its derivative were tested in vitro for application in the treatment of lysosomal storage disease for the first time. Based on these results, polyrotaxanes with disulfide stopper molecules might be promising supramolecular excipients for cellular delivery of α-CDs.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"8 ","pages":"Article 100586"},"PeriodicalIF":6.2,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-09DOI: 10.1016/j.carpta.2024.100578
Shaheen M. Sarkar , Md Lutfor Rahman , Kamrul Hasan , Md. Maksudur Rahman Khan , Emmet J. O'Reilly , Mohd Hasbi Ab. Rahim
The development of reusable, bio-resource based nanocatalysts with high turnover numbers (TONs) is essential for increased sustainability in the chemical sector. Herein, cellulose-supported bio-resourced poly(hydroxamic acid) is employed as a ligand in the synthesis of a palladium nanocomposite (PdNc-PHA) that exhibits higher TONs that previously reported similar systems for the Mizoroki-Heck and Michael addition reactions. The PdNc-PHA catalyst was characterised using Fourier transform infrared spectroscopy (FTIR), field-emission scanning electron microscopy (FE-SEM), energy dispersive X-ray spectrometry (EDX), high-resolution transmission electron microscopy (HR-TEM), X-ray photoelectron spectroscopy (XPS), and inductively coupled plasma-atomic emission spectroscopy (ICP-AES) analyses. Results showed that the PdNc-PHA catalyst exhibits excellent durability and high catalytic activity in the Mizoroki-Heck and Michael addition reactions, leading to high yields of the desired corresponding products. The Mizoroki-Heck reaction of aryl/heteroaryl chlorides with olefins resulted in the production of cross-coupled products, while the Michael addition reaction of phenol/thiophenol and aliphatic cyclic/alicyclic amines with a variety of olefins synthesised the corresponding O-, S-, and N-alkylated products. The recycle and reusability of the catalyst were tested using 4-nitrochlorobenzene and butyl acrylate. The results demonstrated that the catalyst maintained its catalytic activity effectively for up to ten cycles without any noticeable loss in performance. This research represents a promising strategy for efficient catalysis based on bio-waste as a wealth material.
{"title":"Development of cellulose-supported Pd-nanocatalyst for the heck coupling and michael addition reactions","authors":"Shaheen M. Sarkar , Md Lutfor Rahman , Kamrul Hasan , Md. Maksudur Rahman Khan , Emmet J. O'Reilly , Mohd Hasbi Ab. Rahim","doi":"10.1016/j.carpta.2024.100578","DOIUrl":"10.1016/j.carpta.2024.100578","url":null,"abstract":"<div><div>The development of reusable, bio-resource based nanocatalysts with high turnover numbers (TONs) is essential for increased sustainability in the chemical sector. Herein, cellulose-supported bio-resourced poly(hydroxamic acid) is employed as a ligand in the synthesis of a palladium nanocomposite (<strong>PdNc-PHA</strong>) that exhibits higher TONs that previously reported similar systems for the Mizoroki-Heck and Michael addition reactions. The <strong>PdNc-PHA</strong> catalyst was characterised using Fourier transform infrared spectroscopy (FTIR), field-emission scanning electron microscopy (FE-SEM), energy dispersive X-ray spectrometry (EDX), high-resolution transmission electron microscopy (HR-TEM), X-ray photoelectron spectroscopy (XPS), and inductively coupled plasma-atomic emission spectroscopy (ICP-AES) analyses. Results showed that the <strong>PdNc-PHA</strong> catalyst exhibits excellent durability and high catalytic activity in the Mizoroki-Heck and Michael addition reactions, leading to high yields of the desired corresponding products. The Mizoroki-Heck reaction of aryl/heteroaryl chlorides with olefins resulted in the production of cross-coupled products, while the Michael addition reaction of phenol/thiophenol and aliphatic cyclic/alicyclic amines with a variety of olefins synthesised the corresponding O-, S-, and <em>N</em>-alkylated products. The recycle and reusability of the catalyst were tested using 4-nitrochlorobenzene and butyl acrylate. The results demonstrated that the catalyst maintained its catalytic activity effectively for up to ten cycles without any noticeable loss in performance. This research represents a promising strategy for efficient catalysis based on bio-waste as a wealth material.</div></div>","PeriodicalId":100213,"journal":{"name":"Carbohydrate Polymer Technologies and Applications","volume":"8 ","pages":"Article 100578"},"PeriodicalIF":6.2,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142432109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号