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Investigation of the effects of indoor air stability on the airborne transmission of droplets from violent respiratory events 调查室内空气稳定性对暴力呼吸事件飞沫在空气中传播的影响
Pub Date : 2024-07-20 DOI: 10.1016/j.indenv.2024.100036
Xiaorui Deng , Guangcai Gong , Xudong Yang

Indoor air stability is a condition under which the indoor temperature gradients can affect the trajectories of constant breathing flows. However, it remains unclear how indoor air stability affects the airborne contaminants from violent respiratory events such as coughing. Here, we report a study of the dispersion of airborne droplets from coughing under different indoor air stability conditions. The distributions of droplets from coughing processes under stable and unstable conditions were compared. The results revealed that the stable conditions confined the coughed droplets to the breathing zone of the droplet host, whereas the unstable conditions intensified the dispersion of droplets and reduced their local concentration. The dimensionless vertical distance of the droplet cloud under the stable condition was 4 times longer than that of the unstable condition at t = 15 s. In addition, we observed that high ventilation rate caused an intense mixing of the indoor air, thus weakening the effect of indoor air stability on the propagation of droplet cloud. Personal exposure of the stable condition was 6.5 times larger than that of the unstable condition at a ventilation rate of 2.1 ACH, while it decreased to lower than half of that of the unstable condition at 7.1 ACH and 12.3 ACH. Personal exposure to the indoor environment should be assessed by simultaneously considering the indoor air stability conditions and ventilation rates. This study has provided insights into the transmission of cough droplets in indoor environments and has practical significance for preventing the spread of contagious diseases.

室内空气稳定性是指室内温度梯度会影响持续呼吸气流轨迹的一种情况。然而,室内空气稳定性如何影响咳嗽等剧烈呼吸事件产生的空气污染物,目前仍不清楚。在此,我们报告了在不同室内空气稳定性条件下咳嗽产生的空气传播飞沫的扩散研究。我们比较了稳定和不稳定条件下咳嗽过程中产生的飞沫的分布情况。结果表明,稳定条件下,咳嗽产生的飞沫被限制在飞沫宿主的呼吸区域内,而不稳定条件下,飞沫的扩散加剧,局部浓度降低。在 t = 15 秒时,稳定条件下液滴云的无量纲垂直距离是不稳定条件下的 4 倍。此外,我们还观察到,高通风率导致室内空气剧烈混合,从而削弱了室内空气稳定性对液滴云传播的影响。在通风率为 2.1 ACH 时,稳定状态下的个人暴露量是不稳定状态下的 6.5 倍,而在通风率为 7.1 ACH 和 12.3 ACH 时,个人暴露量则下降到不稳定状态下的一半以下。在评估个人暴露于室内环境的情况时,应同时考虑室内空气的稳定性条件和通风率。这项研究为了解咳嗽飞沫在室内环境中的传播提供了见解,对预防传染病的传播具有实际意义。
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引用次数: 0
Coupled indoor air quality and dynamic thermal modelling to assess the potential impacts of standalone HEPA filter units in classrooms 耦合室内空气质量和动态热模型,评估教室中独立式高效空气过滤器的潜在影响
Pub Date : 2024-07-10 DOI: 10.1016/j.indenv.2024.100034
Henry C. Burridge , Sen Liu , Sara Mohamed , Samuel G.A. Wood , Cath J. Noakes

The quality of the classroom environment, including ventilation, air quality and thermal conditions, has an important impact on children’s health and academic achievement. The use of portable HEPA filter air cleaners is widely suggested as a strategy to mitigate exposure to particulate matter and airborne viruses. However, there is a need to quantify the relative benefits of such devices including the impacts on energy use. We present a simple coupled dynamic thermal and air quality model and apply it to naturally ventilated classrooms, representative of modern and Victorian era construction. We consider the addition of HEPA filters with, and without, reduced opening of windows, and explore concentrations of carbon dioxide (CO2), particulate matter PM2.5, airborne viral RNA, classroom temperature and energy use. Results indicate the addition of HEPA filters was predicted to reduce PM2.5 by 40–60 % and viral RNA by 30–50 % depending on the classroom design and window opening behaviour. The energy cost of running HEPA filters is likely to be only 1 %–2 % of the classroom heating costs. In scenarios when HEPA filters were on and window opening was reduced (to account for the additional clean air delivery rate of the filters), the heating cost was predicted to be reduced by as much as − 13 %, and these maximum reductions grew to − 46 % in wintertime simulations. In these scenarios the HEPA filters result in a notable reduction in PM2.5 and viral RNA, but the CO2 concentration is significantly higher. The model provides a mechanism for exploring the relative impact of ventilation and air cleaning strategies on both exposures and energy costs, enabling an understanding of where trade-offs lie.

教室环境的质量,包括通风、空气质量和温度条件,对儿童的健康和学习成绩有着重要影响。人们普遍建议使用便携式 HEPA 过滤器空气净化器,作为减少接触微粒物质和空气传播病毒的一种策略。然而,有必要量化此类设备的相对优势,包括对能源使用的影响。我们提出了一个简单的动态热和空气质量耦合模型,并将其应用于自然通风的教室(代表现代和维多利亚时代的建筑)。我们考虑了增加或不增加高效过滤器、减少开窗的情况,并探讨了二氧化碳 (CO2)、颗粒物 PM2.5、空气传播病毒 RNA、教室温度和能源使用的浓度。结果表明,根据教室的设计和开窗情况,添加高效空气过滤器预计可使 PM2.5 降低 40-60%,病毒 RNA 降低 30-50%。运行高效过滤器的能源成本可能仅占教室供暖成本的 1%-2%。在开启高效过滤器并减少开窗次数的情况下(考虑到过滤器额外的洁净空气输送率),预计供暖成本可降低-13%,而在冬季模拟中,最大降低幅度可达-46%。在这些情况下,高效空气过滤器显著降低了 PM2.5 和病毒 RNA 的浓度,但二氧化碳浓度却明显升高。该模型提供了一种机制,用于探索通风和空气清洁策略对暴露和能源成本的相对影响,从而了解权衡利弊的关键所在。
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引用次数: 0
Influence of uncomfortable environmental conditions on odor detection thresholds for n-butanol determined with a dynamic dilution olfactometer and in room air 不舒适环境条件对正丁醇气味检测阈值的影响(用动态稀释嗅觉仪和室内空气测定
Pub Date : 2024-07-05 DOI: 10.1016/j.indenv.2024.100035
Vanessa Thiele , Christian Monsé , Madlen David , Malgorzata Debiak , Marike Kolossa-Gehring , Thomas Brüning , Jürgen Bünger , Kirsten Sucker

Odor guide values (OGV) are used when a person is exposed to an odor in a room and complains about odor annoyance. OGV are derived from odor detection thresholds (ODT) measured under standard environmental conditions. The study question was whether uncomfortable environmental conditions alter odor perception and should therefore be considered when applying OGV. ODT for n-butanol were determined with an olfactometer and in room air. Twenty healthy, non-smoking volunteers (10 women/10 men, 19–50 years) were selected and trained compliant with the European Standard for Olfactometry EN 13725:2022. Standard conditions were an average temperature between 22 °C and 23 °C, warm light (2800 Kelvin), quiet fan noise (45 dB), 415 ppm carbon dioxide (CO2), and relative humidity between 34 % and 42 %. On each test day, one of five conditions was examined: high temperature (26°C), cold light (6500 Kelvin), traffic noise (70 dB with peaks up to 85 dB), 1000 ppm CO2 and 4000 ppm CO2. Comparability of log-transformed ODT values was assessed by Bland-Altman plot analysis. None of the five conditions systematically affected ODT, either when measured with an olfactometer or in room air. Compared to standard conditions (Limits of Agreement (± LoA) 1.03), the variability of ODT was higher at high temperature (± LoA 1.70) and traffic noise (± LoA 1.45), but not at cold light (± LoA 1.02), 1000 ppm CO2 (± LoA 0.87) or 4000 ppm CO2 (± LoA 0.93). The results show that OGV can be used in uncomfortable environmental conditions. However, because ODT were lower or higher in a few subjects at high temperatures and traffic noise, individual occupant’s perception of temperature and noise should always be considered when applying the OGV concept. Furthermore, the results confirm that the experimental determination of ODT should be performed under controlled and standardized environmental conditions.

当一个人接触到房间里的某种气味并抱怨气味烦人时,就会使用气味指导值(OGV)。OGV 是根据在标准环境条件下测量的气味检测阈值 (ODT) 得出的。研究的问题是,不舒适的环境条件是否会改变对气味的感知,因此在应用 OGV 时应加以考虑。正丁醇的 ODT 是通过嗅觉仪在室内空气中测定的。按照欧洲嗅觉测量标准 EN 13725:2022 挑选了 20 名健康、不吸烟的志愿者(10 名女性/10 名男性,19-50 岁),并对他们进行了培训。标准条件为:平均温度在 22 °C 至 23 °C 之间、暖光(2800 开尔文)、安静的风扇噪音(45 分贝)、415 ppm 二氧化碳(CO2)以及 34 % 至 42 % 的相对湿度。在每个测试日,测试五种条件中的一种:高温(26°C)、冷光(6500 开尔文)、交通噪音(70 分贝,峰值可达 85 分贝)、1000 ppm 二氧化碳和 4000 ppm 二氧化碳。通过布兰德-阿尔特曼图谱分析评估了对数变换后 ODT 值的可比性。无论是使用嗅觉仪还是在室内空气中测量,这五种条件都不会对 ODT 产生系统性影响。与标准条件(± LoA)1.03 相比,在高温(± LoA 1.70)和交通噪音(± LoA 1.45)条件下,ODT 的变异性更高,但在冷光(± LoA 1.02)、1000 ppm CO2(± LoA 0.87)或 4000 ppm CO2(± LoA 0.93)条件下,ODT 的变异性则不高。结果表明,OGV 可以在不舒适的环境条件下使用。然而,由于在高温和交通噪音条件下,少数受试者的 ODT 值较低或较高,因此在应用 OGV 概念时,应始终考虑到乘员对温度和噪音的感知。此外,研究结果还证实,ODT 的实验测定应在受控和标准化的环境条件下进行。
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引用次数: 0
Per- and polyfluoroalkyl substances (PFAS) in paired tap water and house dust from United States homes 美国家庭成对自来水和室内灰尘中的全氟和多氟烷基物质 (PFAS)
Pub Date : 2024-06-30 DOI: 10.1016/j.indenv.2024.100033
Nicole M. DeLuca , Jason Boettger , Kelsey E. Miller , Christopher Fuller , Jeffrey M. Minucci , Peter J. Ashley , David Cox , Gary DeWalt , Warren Friedman , Eugene A. Pinzer , Karen D. Bradham , James McCord , Elaine A. Cohen Hubal

Most people in the United States have been exposed to per- and polyfluoroalkyl substances (PFAS) which have been linked to a wide array of adverse health conditions in adults and children. The consumption of contaminated drinking water is an important human exposure pathway to PFAS. Residential sources also contribute to PFAS exposure through dermal contact and ingestion of house dust, which acts as an aggregate of chemicals from sources like furnishing materials and consumer products. The U.S. Department of Housing and Urban Development (HUD) conducted the first nationwide survey of residential hazards called the American Healthy Homes Survey (AHHS) in 2005, followed by a second survey (AHHS II) in 2017. The U.S. Environmental Protection Agency (EPA) collaborated with HUD on both efforts and subsequently analyzed PFAS in household tap water and house dust collected from the same homes during the AHHS II study. This study leverages these paired samples to investigate potentially important exposure sources and pathways in the residential environment. Here we report results for paired household tap water and house dust samples from 241 homes for 13 and 16 PFAS chemicals, respectively. All 13 targeted chemicals were detected in the household tap water samples with detections ranging from 100 % for PFBS to 1 % for PFNS, and all 16 targeted chemicals were detected in the house dust samples with detections ranging from 97 % for PFOA to 9 % for PFNS. Four chemicals (PFOA, PFOS, PFHxS, and PFHpA) were measured above the limit of detection in at least 50 % of the samples in both media. All households had at least one of the targeted PFAS detected in both their tap water and house dust. Results provided evidence that geographical factors, such as proximity to ambient contamination sources, were main drivers of PFAS contamination in tap water, while PFAS contamination in house dust was driven mainly by within-home sources. Exposure estimates calculated from the measured PFAS concentrations highlight the importance of addressing potential sources of exposure to PFAS within homes in addition to ambient sources affecting communities’ drinking water, particularly to reduce children’s exposure to these chemicals.

美国大多数人都接触过全氟烷基和多氟烷基物质 (PFAS),这些物质与成人和儿童的多种不良健康状况有关。饮用受污染的饮用水是人类接触 PFAS 的一个重要途径。通过皮肤接触和摄入室内灰尘也是接触 PFAS 的住宅来源,室内灰尘是来自家具材料和消费品等来源的化学物质的集合体。美国住房和城市发展部(HUD)于 2005 年开展了名为 "美国健康住宅调查"(AHHS)的首次全国性住宅危害调查,并于 2017 年开展了第二次调查(AHHS II)。美国环境保护署(EPA)与住房和城市发展部合作开展了这两项工作,并随后分析了 AHHS II 研究期间从相同住宅收集的家庭自来水和房屋灰尘中的 PFAS。本研究利用这些配对样本来调查住宅环境中潜在的重要暴露源和途径。在此,我们报告了对来自 241 个家庭的成对家庭自来水和室内灰尘样本分别进行 13 种和 16 种全氟辛烷磺酸化学物质检测的结果。家庭自来水样本中检测到了全部 13 种目标化学物质,其中全氟辛烷磺酸的检出率为 100%,全氟萘磺酸的检出率为 1%;家庭灰尘样本中检测到了全部 16 种目标化学物质,其中全氟辛酸的检出率为 97%,全氟萘磺酸的检出率为 9%。在两种介质中,至少 50% 的样本中检测到的四种化学物质(PFOA、PFOS、PFHxS 和 PFHpA)超过了检测限。所有家庭的自来水和室内灰尘中都检测到了至少一种目标全氟辛烷磺酸。结果证明,地理因素(如与环境污染源的距离)是自来水中 PFAS 污染的主要驱动因素,而室内灰尘中的 PFAS 污染则主要由室内污染源驱动。根据测得的全氟辛烷磺酸浓度计算出的暴露估计值突出表明,除了影响社区饮用水的环境污染源外,解决家庭中潜在的全氟辛烷磺酸暴露源也非常重要,尤其是为了减少儿童对这些化学品的暴露。
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引用次数: 0
Algorithm-driven estimation of household cooking activity and its impact on indoor PM2.5 assessments 算法驱动的家庭烹饪活动估算及其对室内 PM2.5 评估的影响
Pub Date : 2024-06-29 DOI: 10.1016/j.indenv.2024.100032
Sanjana Bhaskar , Andrew Shapero , Futu Chen , MyDzung T. Chu , Rachel C. Nethery , Jaime E. Hart , Gary Adamkiewicz

Background

Household PM2.5 exposures have adverse health effects, and cooking behaviors are an important source of PM2.5 in the home. There is a need for accurate measures of cooking activity to better understand its associations with household PM2.5 since self-reported surveys are often subject to recall bias and misreporting of cooking events.

Objective

In this study, we aimed to address limitations associated with a self-reported cooking metric, by using temperature data to estimate cooking activity.

Methods

We developed an algorithm to identify cooking events at the 5-minute level using real-time temperature data measured near the stove and in the living room, across 148 households in Chelsea and Dorchester, MA. We compared the number of cooking events identified by this algorithm with cooking events self-reported by participants in daily activity logs and survey responses, and further assessed how these metrics differed with respect to their associations with occurrence of peak PM2.5, in mixed effects logistic regression models.

Results

We found that 65 % of the cooking events identified by the algorithm were not reported by participants. Furthermore, households classified as frequent vs infrequent cooking households using the algorithm had a larger difference in indoor PM2.5 levels, compared to households classified by self-report. In mixed effects logistic regression models for elevated household PM2.5 levels, we observed much stronger associations between household PM2.5 and algorithm-derived cooking activity (OR: 2.85 [95 % CI: 2.76, 2.95]) as compared to the association between household PM2.5 and self-reported cooking activity (OR: 1.22 [95 % CI: 1.17, 1.27] for stove use and OR: 1.67 [95 % CI: 1.58, 1.76] for grill use/frying/broiling/sauteing).

Significance

Overall, the algorithm developed in this study presents a data-driven approach to collecting cooking activity data in U.S. households, that may be more indicative of actual cooking events and also more predictive of household PM2.5 in indoor environmental models.

背景家庭 PM2.5 暴露会对健康产生不利影响,而烹饪行为是家庭 PM2.5 的一个重要来源。我们开发了一种算法,利用在马萨诸塞州切尔西和多尔切斯特 148 个家庭的炉灶附近和客厅测量到的实时温度数据来识别 5 分钟级别的烹饪活动。我们将该算法识别出的烹饪事件数量与参与者在日常活动日志和调查回复中自行报告的烹饪事件数量进行了比较,并在混合效应逻辑回归模型中进一步评估了这些指标与 PM2.5 峰值发生率之间的关联差异。此外,与通过自我报告进行分类的家庭相比,使用该算法划分为经常烹饪和不经常烹饪的家庭的室内 PM2.5 水平差异更大。在家庭 PM2.5 水平升高的混合效应逻辑回归模型中,我们观察到,与家庭 PM2.5 与自我报告的烹饪活动之间的关系(炉灶使用 OR:1.22 [95 % CI:1.17, 1.27],OR:1.总体而言,本研究中开发的算法提出了一种数据驱动的方法来收集美国家庭的烹饪活动数据,这种方法可能更能反映实际的烹饪活动,也更能预测室内环境模型中的家庭 PM2.5。
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引用次数: 0
Assessment of methods for predicting physical and chemical properties of organic compounds 评估预测有机化合物物理和化学特性的方法
Pub Date : 2024-06-28 DOI: 10.1016/j.indenv.2024.100031
Tunga Salthammer

For the ecotoxicological assessment of a chemical substance it is important to know its partition behavior. In inanimate nature these are water, soil and air. Indoors it is gas and particle phase, settled house dust and surfaces. Due to the complex interaction of molecules with environmental compartments, their dynamics is usually modeled. However, this requires as precise information as possible about the physical and chemical properties as well as reaction pathways. Traditionally, the parameters necessary for the respective modeling are determined experimentally. However, with the increasing performance of computers, prediction tools based on structure-activity relationships and quantum mechanical calculations have become increasingly popular. The algorithms underlying the respective tools are highly specialized and mathematically sophisticated. Therefore, scientific expertise and extensive experience are needed to assess whether a specific value is reliable or not. This work provides an overview of available databases and prediction tools. It is intended to support the user in selecting accurate molecular parameters of organic substances in order to be able to make reliable statements about the partitioning of these substances in the indoor environment and about exposure of occupants.

要对化学物质进行生态毒理学评估,就必须了解它的分区行为。在无生命的自然界中,它们是水、土壤和空气。在室内,它们是气相和颗粒相、沉降的室内灰尘和表面。由于分子与环境分区之间存在复杂的相互作用,通常需要对其动态进行建模。然而,这需要尽可能精确的物理和化学特性以及反应路径信息。传统上,建模所需的参数都是通过实验确定的。然而,随着计算机性能的不断提高,基于结构-活性关系和量子力学计算的预测工具越来越受欢迎。这些工具的算法非常专业,在数学上也非常复杂。因此,需要科学专业知识和丰富经验来评估特定数值是否可靠。本作品概述了现有的数据库和预测工具。其目的是帮助用户选择准确的有机物质分子参数,以便能够对这些物质在室内环境中的分配和居住者的暴露情况做出可靠的说明。
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引用次数: 0
Spatial features of CO2 for occupancy detection in a naturally ventilated school building 自然通风校舍中用于探测占用情况的二氧化碳空间特征
Pub Date : 2024-06-23 DOI: 10.1016/j.indenv.2024.100018
Qirui Huang, Marc Syndicus, Jérôme Frisch, Christoph van Treeck

Accurate occupancy information helps to improve building energy efficiency and occupant comfort. Occupancy detection methods based on CO2 sensors have received attention due to their low cost and low intrusiveness. In naturally ventilated buildings, the accuracy of CO2-based occupancy detection is generally low in related studies due to the complex ventilation behavior and the difficulty in measuring the actual air exchange through windows. In this study, we present two novel features for occupancy detection based on the spatial distribution of the CO2 concentration. After a quantitative analysis with Support Vector Machine (SVM) as classifier, it was found that the accuracy of occupancy state detection in naturally ventilated rooms could be improved by up to 14.8 percentage points compared to the baseline, reaching 83.2 % (F1 score 0.84) without any ventilation information. With ventilation information, the accuracy reached 87.6 % (F1 score 0.89). The performance of occupancy quantity detection was significantly improved by up to 25.3 percentage points versus baseline, reaching 56 %, with root mean square error (RMSE) of 11.44 occupants, using only CO2-related features. Additional ventilation information further enhanced the performance to 61.8 % (RMSE 9.02 occupants). By incorporating spatial features, the model using only CO2-related features revealed similar performance as the model containing additional ventilation information, resulting in a better low-cost occupancy detection method for naturally ventilated buildings.

准确的占用信息有助于提高建筑能效和居住舒适度。基于二氧化碳传感器的占用检测方法因其低成本和低侵入性而备受关注。在自然通风建筑中,由于通风行为复杂,且难以测量通过窗户的实际空气交换量,相关研究中基于二氧化碳的占用检测精度普遍较低。在本研究中,我们提出了基于二氧化碳浓度空间分布的两种新型占用检测特征。以支持向量机(SVM)为分类器进行定量分析后发现,在没有任何通风信息的情况下,自然通风房间的占用状态检测准确率可比基线提高 14.8 个百分点,达到 83.2 %(F1 得分为 0.84)。在有通风信息的情况下,准确率达到了 87.6%(F1 得分为 0.89)。与基线相比,仅使用二氧化碳相关特征的占用数量检测性能大幅提高了 25.3 个百分点,达到 56%,均方根误差 (RMSE) 为 11.44 个占用者。附加的通风信息进一步提高了性能,达到 61.8%(均方根误差为 9.02)。通过纳入空间特征,仅使用二氧化碳相关特征的模型显示出与包含额外通风信息的模型相似的性能,从而为自然通风建筑提供了更好的低成本占用检测方法。
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引用次数: 0
Indoor air pollution and hypertension disease burden among women using low-grade fuels 室内空气污染与使用低等级燃料妇女的高血压疾病负担
Pub Date : 2024-06-22 DOI: 10.1016/j.indenv.2024.100028
Chukwuemeka G. Ogbonna , Godwin E. Mbamalu , Udo E. Ahuchaogu , Samuel I. Ogbaa , Ijeoma J. Ukpabi

Exposures to indoor air pollution from the combustion of Low-grade Fuels (LgFs) is a leading risk factor for global disease burden. Emerging evidence suggest a potential role of PM2.5 exposures in Blood Pressure (BP) elevation. This study assessed the effects of Indoor Air Pollution (IAP) from the use of LgFs on hypertension disease burden among women in low-income settlements. We measured the kitchen concentrations and personal exposures to PM2.5 for users of LgFs compared with users of LPG in the city of Aba, Nigeria. The study also assessed hypertension markers for 328 adult women in the population. Association between PM2.5 exposures and BP was modelled with hierarchical multiple regression, adjusting for major covariates. The indoor PM2.5 concentrations for users of LgFs ranged from 47.5 to 800.0 μg/m3 while that for LPG users ranged from 33.0 to 112.5 μg/m3. The mean personal exposures were 152.3 μg/m3 and 58.3 μg/m3 for users of LgFs and LPG, respectively. The age-standardized hypertension prevalence in the population was 24.4 % and 15.6 % for users of LgFs and LPG, respectively. Exposures to PM2.5 moderately predicted SBP among users of LgFs but not among LPG users; the increase in 1 μg/m3 of PM2.5 exposure resulted to 0.44 mmHg increase in SBP among users LgFs. Long-term exposures to IAP from the use of low-grade fuels is associated with increased SBP and greater risks of systemic hypertension. These findings reinforce the need for public policies towards improving access to, and affordability of LPG as an alternative household fuel.

低等级燃料(LgFs)燃烧产生的室内空气污染是造成全球疾病负担的主要风险因素。新的证据表明,PM2.5 的暴露可能会导致血压(BP)升高。本研究评估了使用低浓度燃料造成的室内空气污染(IAP)对低收入住区妇女高血压疾病负担的影响。我们测量了尼日利亚阿巴市使用低温室气体的用户与使用液化石油气的用户的厨房浓度以及个人接触 PM2.5 的情况。研究还评估了人口中 328 名成年女性的高血压指标。PM2.5暴露与血压之间的关系采用分层多元回归建模,并对主要协变量进行了调整。使用液化石油气的用户的室内 PM2.5 浓度介于 47.5 至 800.0 μg/m3 之间,而使用液化石油气的用户的室内 PM2.5 浓度介于 33.0 至 112.5 μg/m3 之间。使用低浓度荧光粉和液化石油气的用户的个人平均暴露量分别为 152.3 μg/m3 和 58.3 μg/m3。使用低温室气体和液化石油气的人群中,年龄标准化的高血压患病率分别为 24.4% 和 15.6%。PM2.5的暴露量可适度预测低温室气体使用者的SBP,但不能预测液化石油气使用者的SBP;PM2.5暴露量每增加1微克/立方米,低温室气体使用者的SBP就会增加0.44毫米汞柱。长期使用低等级燃料而暴露于 IAP 与 SBP 升高和全身性高血压的风险增大有关。这些研究结果进一步说明,有必要制定公共政策,改善液化石油气作为替代家用燃料的可及性和可负担性。
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引用次数: 0
Quantifying quanta: Determining emission rates from clinical data 量化量子:从临床数据中确定发射率
Pub Date : 2024-06-21 DOI: 10.1016/j.indenv.2024.100025
Benjamin Jones , Christopher Iddon , Max Sherman

It is important to quantify uncertainty in the viable genomic material encapsulated in the respiratory particles emitted by infected people so that it can be converted into an emission rate as a function of respiratory and metabolic activities and used to estimate the probability of infection for an indoor scenario. Clinical measurements of viral loads for SARS-CoV-2 made using infection surveys, Gesundheit-II samplers, and human challenge studies are evaluated and a mathematical model is derived to estimate the quantum emission rate as a function of the genomic and viable viral loads. Modelled emission rates for SARS-CoV-2 agree with clinical data above detection limits. The viral load is found to vary over at least 6 orders of magnitude because it is person and time dependent, and contingent on many other factors that are difficult to quantify. It is similarly large for other respiratory pathogens. Therefore, the genomic and viable-virion emission rates display similar heterogeneity. When emission rates are used to estimate absolute infection risk using the Wells-Riley model, the predictions are so uncertain that they cannot be used in any meaningful way to provide useful quantitative guidance for designing indoor spaces.

重要的是要量化感染者散发的呼吸道微粒中包裹的可存活基因组物质的不确定性,以便将其转化为与呼吸和代谢活动相关的散发率,并用于估算室内情况下的感染概率。利用感染调查、Gesundheit-II 采样器和人体挑战研究对 SARS-CoV-2 病毒载量的临床测量结果进行了评估,并推导出一个数学模型,用于估算作为基因组和存活病毒载量函数的量子排放率。建模得出的 SARS-CoV-2 发射率与高于检测限的临床数据一致。病毒载量至少有 6 个数量级的变化,因为它与人和时间有关,并取决于其他许多难以量化的因素。其他呼吸道病原体的病毒量也同样很大。因此,基因组和存活病毒的排放率也显示出类似的异质性。当使用 Wells-Riley 模型来估算绝对感染风险时,排放率的预测结果非常不确定,无法以任何有意义的方式为室内空间的设计提供有用的定量指导。
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引用次数: 0
Long term monitoring of CO2 levels and ventilation rates in a naturally ventilated residential apartment 长期监测自然通风住宅公寓中的二氧化碳含量和通风率
Pub Date : 2024-06-20 DOI: 10.1016/j.indenv.2024.100030
Martin de Jode

Indoor CO2 levels became particularly topical during the recent COVID-19 pandemic. In this study a long-term investigation of indoor CO2 levels in a 1970s built residential apartment in single occupancy is presented. Three NDIR CO2 sensors were used to measure CO2 levels over a one-year period. Mean CO2 levels over this period were 1278 ± 504 ppm, with elevated CO2 levels of greater than 2000 ppm not uncommon. Subsequent investigations used the single zone mass balance model and the decay of CO2 in the absence of occupants to estimate the ventilation rates in various configurations. A mean natural ventilation rate of 0.16 ACH was estimated with all windows closed. Opening fan light windows resulted in a mean ventilation rate of 2.86 ACH whereas opening all windows increased the mean ventilation rate to 19.1 ACH. Evidence was observed of the effect of both wind speed and indoor-outdoor temperature difference on the ventilation rates. It was concluded that with all windows closed the natural infiltration rate was insufficient to maintain optimal indoor air quality even in single occupancy. Opening the fan light windows was sufficient to achieve satisfactory indoor air quality but insufficient for the effective inhibition of airborne disease transmission.

在最近的 COVID-19 大流行期间,室内二氧化碳含量成为了特别关注的话题。本研究介绍了一项对 20 世纪 70 年代建造的单人住宅公寓室内二氧化碳水平的长期调查。使用三个近红外二氧化碳传感器测量了一年的二氧化碳水平。在此期间,平均二氧化碳浓度为 1278 ± 504 ppm,二氧化碳浓度高于 2000 ppm 的情况并不少见。随后的调查利用单区质量平衡模型和二氧化碳在没有居住者的情况下的衰减来估算不同配置下的通风率。在所有窗户关闭的情况下,平均自然通风率估计为 0.16 ACH。打开扇形采光窗后,平均通风率为 2.86 ACH,而打开所有窗户后,平均通风率增加到 19.1 ACH。有证据表明,风速和室内外温差对通风率都有影响。得出的结论是,在关闭所有窗户的情况下,即使是单人居住,自然渗透率也不足以维持最佳的室内空气质量。打开风扇采光窗足以达到令人满意的室内空气质量,但不足以有效抑制空气传播疾病。
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引用次数: 0
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Indoor Environments
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