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Traditional food, modern food and nutritional value of Sea buckthorn (Hippophae rhamnoides L.): a review 沙棘的传统食品、现代食品及营养价值综述
Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.jfutfo.2023.02.001
Aruhan Chen , Xiaowei Feng , Byambasuren Dorjsuren , Chimedragchaa Chimedtseren , Tsend-Ayush Damda , Chunhong Zhang

Sea buckthorn (Hippophae rhamnoides L.) is a deciduous shrub with high nutritional and therapeutic value belonging to the family sea buckthorn, rich in oleic acid, protein, amino acids and potassium and other nutrients. Sea buckthorn can also treat heart diseases, lung diseases and other diseases. This review aims to sort out the traditional sea buckthorn food and modern sea buckthorn food, and provide important reference value for manufacturers to develop and utilize sea buckthorn. In addition, it also clarifies the nutritional value of sea buckthorn, so as to provide strong support for the comprehensive utilization of sea buckthorn fruit food and the production direction of health care industry.

沙棘(Hippophae rhamnoides L.)是沙棘科一种具有很高营养和治疗价值的落叶灌木,富含油酸、蛋白质、氨基酸和钾等营养物质。沙棘还可以治疗心脏病、肺病等疾病。本文旨在对传统沙棘食品和现代沙棘食品进行梳理,为沙棘生产商开发利用提供重要的参考价值。此外,还明确了沙棘的营养价值,从而为沙棘果类食品的综合利用和保健产业的生产方向提供有力的支持。
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引用次数: 6
The hypoglycemic effect of Lagerstroemia indica L. and Lagerstroemia indica L. f. alba (Nichols.) Rehd. in vitro and in vivo 紫薇和白紫薇的降血糖作用(Nichols.)Rehd。在体外和体内
Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.jfutfo.2023.02.008
Meifang Chang , Adel F. Ahmed , Lili Cui

Lagerstroemia indica L. has a high medicinal value, its bark, leaves and flowers can be used as medicine. Its flowers are reddish, purple, or white, thereinto, the white one is called L. indica Linn. f. alba (Nichols.) Rehd., which is a forma of L. indica. In this paper, the hypoglycemic effects of different extracts from flowers of L. indica (LIF) and L. indica L. f. alba (Nichols.) Rehd. (LIAF) were investigated by α-glucosidase inhibitory method in vitro and alloxan-induced diabetic mice model in vivo, respectively. The results in vitro showed that ethyl acetate extracts (EA) of LIF and LIAF (IC50 = 4.45 and 4.09 µg/mL, resepectively) had the highest inhibitory activity of α-glucosidase, and followed by n-butyl alcohol extracts (BU) (IC50 = 17.01 and 14.58 µg/mL, respectively), and the last was petroleum ether extracts (PE) (IC50 = 103.29 and 112.47 µg/mL, respectively), the activities of all extracts were higher than that of the positive control (acarbose, IC50 = 1 278.83 µg/mL). The results in vivo showed that compared with the model control group, each dose group of LIF could significantly (P < 0.05, P < 0.01 or P < 0.001) decrease fasting blood glucose, total cholesterol (TC) level and malondialdehyde (MDA) content in diabetic mice and increase superoxide dismutase (SOD) level (P < 0.05) in serum. Partial dose groups of LIF could significantly (P < 0.05) decrease postprandial blood glucose, triglyceride (TG) and increase liver glycogen content. Each dose group of LIAF could significantly (P < 0.05, P < 0.01 or P < 0.001) decrease fasting blood glucose, TC level and increase SOD level in serum. Partial dose groups of LIAF could significantly (P < 0.05) decrease TG, MDA level and increase liver glycogen content. These results indicate that LIF and LIAF had effective prevention and treatment effects on the development for diabetes.

紫薇(Lagerstroemia indica L.)具有很高的药用价值,其树皮、叶子和花均可作为药物使用。它的花有红色、紫色或白色,其中白色的被称为L. indica Linn。f.阿尔巴(尼科尔斯)Rehd。,是L. indica的一种。本文研究了籼籼花(L. indica, LIF)和籼籼花(L. f. alba, Nichols.)不同提取物的降糖作用。Rehd。分别采用α-葡萄糖苷酶体外抑制法和四氧嘧啶诱导的糖尿病小鼠体内模型法对LIAF进行了研究。体外实验结果表明,LIF和LIAF的乙酸乙酯提取物(EA) (IC50 = 4.45和4.09µg/mL)对α-葡萄糖苷酶的抑制活性最高,其次是正丁醇提取物(BU) (IC50 = 17.01和14.58µg/mL),最后是石油醚提取物(PE) (IC50 = 103.29和112.47µg/mL),其活性均高于阳性对照(阿卡波糖,IC50 = 1 278.83µg/mL)。体内实验结果显示,与模型对照组相比,LIF各剂量组均能显著(P <0.05, P <0.01或P <0.001)降低糖尿病小鼠空腹血糖、总胆固醇(TC)水平和丙二醛(MDA)含量,升高超氧化物歧化酶(SOD)水平(P <0.05)。部分剂量组LIF能显著(P <0.05)降低餐后血糖、甘油三酯(TG),增加肝糖原含量。LIAF各剂量组均能显著(P <0.05, P <0.01或P <0.001)降低空腹血糖、TC水平,升高血清SOD水平。部分剂量组LIAF可显著(P <0.05)降低TG、MDA水平,提高肝糖原含量。这些结果表明,LIF和LIAF对糖尿病的发展具有有效的预防和治疗作用。
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引用次数: 0
Exploring phytochemicals of Withania somnifera from different vicinity for functional foods 不同产地荞麦的植物化学成分及其在功能性食品中的应用
Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.jfutfo.2023.02.010
Pooja Dhama , Xianting Ding , Alok Sharma

The well-known relation between food and bioactives explores the great prospective of innovative and novel food to maintain or improve health, increasing the demand investigating advance products with medicinal effect. Withania somnifera also known as ‘Ashwagandha’ in India, is one of the most utilized plants in different ancient medicine systems. The present work is an effort to develop a knowledge-based concept and a quality control approach for the development of functional foods. The study took into account the standardization criteria and examined how different geographies or different field sites (of India) would influence the phytoconstituents and their distribution in the different samples of W. somnifera. Phytoconstituents level were strongly influenced by soil quality, cultivar, and growing season. An increase in phenolic content, flavonoid content, antioxidants and the quality yield, were all correlated with increased phytoconstituent concentrations. The highest hydro-methanolic extract yield (by reflux (Soxhlet), sonication (20 min) and maceration (16 h) was from the sample collected from Rajasthan (18.61%, m/m) followed by West Bengal (11.21%) and Madhya Pradesh (12.67%) respectively. The methanolic extract of Rajasthan sample (produced by the reflux (Soxhlet) extraction method) had the highest concentrations of flavonoids (65.32 mg quercetin equivalent (QE)/g) and the total phenols (60.35 mg gallic acid equivalent (GAE)/g), while Madhya Pradesh sample (distilled water reflux (Soxhlet)) extract had the highest antioxidant content (74.13 %). High performance thin layer chromatography (HPTLC) method was also utilized for identification of withanolides A. Chromatographic separations were carried out using V(ethyl acetate):V(toluene): V(acetic acid) = 9.1:1:0.6 as the mobile phase. The gas chromatograph-mass spectrometer (GC-MS) study of hydro-methanolic Soxhlet extract of W. somnifera from 3 different regions of India was done and the total phytochemical substances identified were 132 in sample from Rajasthan, 107 in sample from West Bengal, and 164 in sample from Madhya Pradesh respectively. To conclude, the present study demonstrates how, within a framework of integrated agricultural practices, yield and phytochemicals merge into a new paradigm of functional foods.

众所周知,食品与生物活性之间的关系为创新和新型食品的发展开辟了广阔的前景,以维持或改善健康,增加了对具有药用效果的先进产品的研究需求。Withania somnifera在印度也被称为“Ashwagandha”,是不同古代医学系统中使用最多的植物之一。本研究旨在建立以知识为基础的概念和开发功能性食品的质量控制方法。该研究考虑了标准化标准,并检查了(印度)不同的地理位置或不同的田间地点将如何影响W. somnifera不同样品中的植物成分及其分布。植物成分水平受土壤质量、品种和生长季节的影响较大。酚类含量、类黄酮含量、抗氧化剂含量和优质产量的增加都与植物成分浓度的增加有关。拉贾斯坦邦(18.61%,m/m)、西孟加拉邦(11.21%)和中央邦(12.67%)的水甲醇提取率最高(回流法)、超声法(20 min)和浸渍法(16 h)。其中,拉贾斯坦邦甲醇提取物(回流(索氏)法)总黄酮含量最高(65.32 mg槲皮素当量(QE)/g),总酚含量最高(60.35 mg没食子酸当量(GAE)/g),中央邦甲醇提取物(蒸馏水回流(索氏)法)抗氧化剂含量最高(74.13%)。以V(乙酸乙酯):V(甲苯):V(乙酸) = 9.1:1:6 .6为流动相进行色谱分离。采用气相色谱-质谱(GC-MS)对印度3个不同地区的苦楝水甲醇索氏提取物进行了分析,分别在拉贾斯坦邦、西孟加拉邦和中央邦样品中鉴定出132种、107种和164种植物化学物质。总而言之,本研究表明,在综合农业实践的框架内,产量和植物化学物质如何融合到功能食品的新范式中。
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引用次数: 0
Review on herbal tea as a functional food: classification, active compounds, biological activity, and industrial status 凉茶作为功能性食品的分类、活性成分、生物活性及工业现状综述
Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.jfutfo.2023.02.002
Yuchao Liu , Chunyan Guo , Erhuan Zang , Ruyu Shi , Qian Liu , Min Zhang , Keyong Zhang , Minhui Li

Most herbal tea infusions use edible medicinal plants as raw material and are consumed daily. Although herbal tea has a long history of health care applications worldwide, there is a lack of systematic research on the classification and functional nutritional value of various herbal teas. In recent years, the discovery of the rich biological activities and health benefits of herbal tea has become a driving force for researchers interested in its development as a functional food. However, the shortcomings of herbal tea products are not fully known. In particular, the quality evaluation system is not perfect, and there is insufficient data on the mechanism of action of herbal teas in their traditional uses. To better understand the functions and mechanisms of various herbal teas, this article reviews the classification, effective chemical composition, main biological activities, and mechanism of action of herbal teas. Finally, the current advantages, limitations, and direction of future development of herbal tea are determined and discussed.

大多数凉茶都使用可食用的药用植物作为原料,每天饮用。虽然凉茶在世界范围内具有悠久的保健应用历史,但对各种凉茶的分类和功能营养价值缺乏系统的研究。近年来,凉茶丰富的生物活性和保健功效的发现成为研究人员将其开发为功能性食品的动力。然而,凉茶产品的缺点并不完全为人所知。特别是草药茶的质量评价体系尚不完善,传统用途中草药茶的作用机理资料不足。为了更好地了解各种凉茶的功能和作用机制,本文对凉茶的分类、有效化学成分、主要生物活性和作用机制进行了综述。最后,对凉茶目前的优势、局限性和未来的发展方向进行了确定和探讨。
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引用次数: 6
A review on the application, phytochemistry and pharmacology of Polygonatum odoratum, an edible medicinal plant 可食药用植物黄精的应用、植物化学及药理研究进展
Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.jfutfo.2023.02.006
Jingyi Bi , Huiyong Fang , Jianyun Zhang , Litao Lu , Xian Gu , Yuguang Zheng

Polygonatum odoratum is distributed in several countries around the world as a medicinal and dual-use plant, and its rhizomes are used in China as a traditional Chinese medicine, also as vegetables, foods, functional foods or tea, with a history of application for more than 2 000 years, with precise efficacy and no toxic side effects. However, few reviews are published on its chemical composition and its pharmacological effects. There are many components of P. odoratum, including steroidal saponins, homoisoflavanones, isoflavones, flavonoids, alkaloids, lignin, volatile oil, polysaccharides and lectins. In this review, recent advances of the history and consumption of P. odoratum, the types of chemical components, and the pharmacological effects manifested in antitumour and anticancer, antioxidant, slowing senescence, relieving fatigue and immune regulation are summarized and discussed. Presumably, the main active ingredients of the plant are homoisoflavanones, polysaccharides, saponins, and lectins. The review provides a reference for its development and utilization in the field of functional food and medicine in the future.

黄精作为药用和军民两用植物分布在世界多个国家,其根茎在中国作为中药,也作为蔬菜、食品、功能食品或茶叶使用,已有2000多年的应用历史,功效精准,无毒副作用。然而,对其化学成分和药理作用的研究文献很少。臭椿有许多成分,包括甾体皂苷、异黄酮、异黄酮、类黄酮、生物碱、木质素、挥发油、多糖和凝集素。本文就香桐的历史、消费、化学成分类型以及在抗肿瘤、抗癌、抗氧化、延缓衰老、缓解疲劳和调节免疫等方面的药理作用等方面的最新进展进行了综述和讨论。据推测,这种植物的主要活性成分是同异黄酮、多糖、皂苷和凝集素。为今后其在功能食品和医药领域的开发利用提供参考。
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引用次数: 4
Bioactive effects advances of natural polysaccharides 天然多糖生物活性研究进展
Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.jfutfo.2023.02.005
Ruyu Shi , Ba Dan , Lijuan Lü

Taking into account the rising incidence of metabolic diseases, it is an urgent need for effective treatments to control human health problems. Natural polysaccharides have been found effective on metabolic diseases in more and more researches. In the context of serious side effects of drugs, natural polysaccharides will be verified in the prevention and treatment of metabolic diseases and show their advantages of low toxicity and high efficiency. This review mainly summarized the activity of polysaccharides from different sources in regulating metabolism, and laid a reference for metabolic diseases by natural polysaccharides.

鉴于代谢性疾病的发病率不断上升,迫切需要有效的治疗方法来控制人类的健康问题。越来越多的研究发现天然多糖对代谢性疾病有治疗作用。在药物副作用严重的背景下,天然多糖在代谢性疾病的预防和治疗方面将得到验证,并显示出其低毒、高效的优势。本文主要综述了不同来源的多糖在调节代谢方面的活性,为天然多糖代谢性疾病的治疗提供参考。
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引用次数: 6
Determination of icariside, hyperoside and psoralen in food by liquid chromatography-tandem mass spectrometry 液相色谱-串联质谱法测定食品中枸杞苷、金丝桃苷和补骨脂素
Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.jfutfo.2023.02.007
Sufang Fan , Junmei Ma , Xiaoxian Yuan , Xu Wang , Yi Wang , Yan Zhang

A high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was built to determine icarside, hyperoside and psoralen in food. The samples were extracted with 70% methanol, the solid and semi-solid hotpot seasoning samples were purified by solid phase extraction column, and then determined by HPLC-MS/MS. Acetonitrile and 0.1% formic acid solution were used as the mobile phase, and the gradient elution was adopted for analysis. As shown in the results, the analytes had good linearity in the range of 0.05−100 ng/mL, and the correlation coeffificients (R2) were greater than 0.999. In this method, the limits of quantitation (LOQ) of psoralen, icariside and hyperoside in liquid samples were 1.25, 25.0 and 12.5 μg/L respectively; while the LOQs of psoralen, icariside and hyperoside in solid samples and hotpot seasoning samples were 1.25, 25.0 and 12.5 μg/kg, respectively. The liquid beverage, solid beverage, health food (in the form of oral liquid, capsule, tablet), integrated alcoholic beverage and solid hotpot seasoning were selected as representative samples and used for method validation. The average spiked recoveries at 3 levels (LOQ, 2 LOQ, 10 LOQ) were in the range of 83.7%−115.0%, and the relative standard deviations were in range of 0.5%−9.4% (n = 6). The method is rapid, accurate and sensitive, which is suitable for the simultaneous determination of icariside, hyperoside and psoralen in different food matrices.

建立了一种高效液相色谱-串联质谱(HPLC-MS/MS)测定食品中iccard苷、金丝桃苷和补骨脂素的方法。样品用70%甲醇提取,固体和半固体火锅调味料用固相萃取柱纯化,然后用HPLC-MS/MS测定。以乙腈和0.1%甲酸溶液为流动相,采用梯度洗脱法进行分析。结果表明,分析物在0.05 ~ 100 ng/mL范围内线性良好,相关系数(R2)均大于0.999。本方法液相样品中补骨脂素、枸杞苷、金丝桃苷的定量限分别为1.25、25.0、12.5 μg/L;固体样品和火锅调味料样品中补骨脂素、枸杞苷和金丝桃苷的检出限分别为1.25、25.0和12.5 μg/kg。选取液体饮料、固体饮料、保健食品(口服液、胶囊、片剂形式)、综合酒精饮料和固体火锅调味料作为代表性样品进行方法验证。3个水平(LOQ、2 LOQ、10 LOQ)的平均加标回收率为83.7% ~ 115.0%,相对标准偏差为0.5% ~ 9.4% (n = 6)。该方法快速、准确、灵敏,适用于同时测定不同食品基质中薯蓣皂苷、金丝桃苷和补骨脂素的含量。
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引用次数: 0
Coagulant compounds in Rubia cordifolia L. 芦花中的混凝剂成分。
Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.jfutfo.2023.02.003
Peiqing Wang , Jiajia Wang , Fatma M. El-Demerdash , Jinfeng Wei

Rubia cordifolia L. belongs to Rubiaceae family. Its medicinal parts are mainly root and rhizome, which is included in the Chinese Pharmacopoeia (2020), has the effect of cooling blood and stopping bleeding, removing stasis and channeling menstruation. However, studies on the hemostatic effect of R. cordifolia mainly focus on extracts, and the hemostatic components are less studied. Therefore, chemical constituents and coagulant activity of R. cordifolia were investigated in this paper. Eleven compounds were isolated and identified from R. cordifolia, including 1-hydroxy-2-methyl-9,10-anthraquinone (1), 1,4-dihydroxy-2-methylanthraquinone (2), palmitic acid (3), tricosanoic acid (4), ω-hydroxypachybasin (5), ursolic acid (6), oleanolic acid (7), rubilactone (8), β-sitosterol (9), cordifoliol (10), 1,3-dihydroxy-2-ethoxymethyl-9,10-anthraquinone (11). ω-Hydroxypachybasin was isolated from Rubia genus for the first time. 1,4-Dihydroxy-2-methylanthraquinone, rubilactone and 1,3-dihydroxy-2-ethoxymethyl-9,10-anthraquinone could remarkably shorten the plasma calcium coating time in vitro, thus indicating that they had procoagulant activity.

茜草属茜草科。其药用部位以根和根茎为主,已被列入《中国药典(2020)》,具有凉血止血、化瘀通经的功效。然而,对堇青花止血作用的研究主要集中在提取物上,对其止血成分的研究较少。因此,本文对堇青花的化学成分和混凝剂活性进行了研究。从堇青花中分离鉴定了11个化合物,分别为1-羟基-2-甲基-9,10-蒽醌(1)、1,4-二羟基-2-甲基蒽醌(2)、棕榈酸(3)、三糖酸(4)、ω-羟基木瓜碱(5)、熊果酸(6)、齐ole果酸(7)、红内酯(8)、β-谷甾醇(9)、堇青花醇(10)、1,3-二羟基-2-乙氧基甲基-9,10-蒽醌(11)。ω-Hydroxypachybasin为首次从鲁柏属植物中分离得到。1,4-二羟基-2-甲基蒽醌、红内酯和1,3-二羟基-2-乙氧基甲基-9,10-蒽醌均能显著缩短体外血浆钙包覆时间,具有促凝活性。
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引用次数: 0
Bibliometric analysis of literature on prevention and treatment of gastric ulcer with natural medicines 天然药物防治胃溃疡文献计量学分析
Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.jfutfo.2023.02.004
Xueying Wang , Xuejiao Wang , Mingyuan Wen , Xiaolong Li

This study aimed to explore the application status of natural products in gastric ulcer research and explore the research hotspots and future research directions. CiteSpace was used to conduct metrological and visual analysis on the number of articles published in the core set of Web of Science database about natural medicines therapy for gastric ulcer, including co-cited journals, co-cited authors, co-cited literatures and keywords. From 1953 to 2021, the number of articles published on natural medicines therapy for gastric ulcer was 1 373, the total number of articles had increased rapidly in recent years. China and the United States were the driving force in this field, and the main research institution was Chinese Univ. Hong Kong. Most of the publications are in the journal Gastroenterology. "peptic ulcer", "Helicobacter pylori", "infection", "duodenal ulcer", "disease", "gastric ulcer", "peptic ulcer disease", "gastric cancer", and "prevalence" were the research frontiers in recent years. This study was the first to conduct literature metrology visualization analysis on the research status and hot spots and development trend of natural medicines against gastric ulcer, in order to provide reference for follow-up researchers to quickly understand the research focus of natural medicines against gastric ulcer and literature retrieval. In addition, this paper also put forward suggestions and prospected for the future development of this field, which will help researchers to open up new directions for future research in this field.

本研究旨在探讨天然产物在胃溃疡研究中的应用现状,探讨其研究热点和未来的研究方向。利用CiteSpace软件对Web of Science数据库核心集关于天然药物治疗胃溃疡的文章发表数量进行计量和可视化分析,包括共被引期刊、共被引作者、共被引文献和关键词。从1953年到2021年,天然药物治疗胃溃疡的文章发表数为1 373篇,近年来文章总数增长迅速。中国和美国是这一领域的推动力,主要研究机构是香港中文大学。大多数出版物都发表在《胃肠病学》杂志上。“消化性溃疡”、“幽门螺杆菌”、“感染”、“十二指肠溃疡”、“疾病”、“胃溃疡”、“消化性溃疡病”、“胃癌”、“患病率”是近年来的研究前沿。本研究首次对抗胃溃疡天然药物的研究现状、研究热点及发展趋势进行文献计量可视化分析,为后续研究者快速了解抗胃溃疡天然药物的研究热点及文献检索提供参考。此外,本文还对该领域的未来发展提出了建议和展望,有助于研究者为该领域未来的研究开辟新的方向。
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引用次数: 0
Effects of bioactive compounds and pharmacological activities in medicinal fruits and vegetables by thermal processing 热处理对药用果蔬生物活性化合物及药理活性的影响
Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2023-09-01 DOI: 10.1016/j.jfutfo.2023.02.009
Jiaqiong Liu , Yang Liu , Xiaoqin Wang

With the advancement of living standards, the role of healthy diets in maintaining well-being has gained prominence. The concept of “medicinal fruits and vegetables” has attracted much research attention recently. Medicinal fruits and vegetables are rich in nutrients and high in edible value, and are also necessary for people's daily diet. In order to better exert the effect of medicinal fruits and vegetables and prolong their shelf life, this paper reviews the effects of common thermal processing methods (boiling, steaming, microwaving, hot air drying, and pasteurization) on the bioactive compounds and pharmacological activities of medicinal fruits and vegetables. It is found that different heat treatment methods have their own advantages and disadvantages, and microwave drying has greater advantages in comparison. Through the summary of the thermal processing methods of medicinal fruits and vegetables, it is expected to provide a theoretical reference for its rational utilization in the field of fruits and vegetables and the improvement of thermal processing methods.

随着生活水平的提高,健康饮食在维持健康方面的作用日益突出。近年来,“药用果蔬”的概念引起了人们的广泛关注。药用水果和蔬菜营养丰富,食用价值高,也是人们日常饮食所必需的。为了更好地发挥药用果蔬的功效,延长其保质期,本文综述了常用的热加工方法(煮、蒸、微波、热风干燥和巴氏杀菌)对药用果蔬生物活性成分和药理活性的影响。研究发现,不同的热处理方式各有优缺点,微波干燥在比较中具有更大的优势。通过对药用果蔬热加工方法的总结,期望为其在果蔬领域的合理利用和热加工方法的改进提供理论参考。
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引用次数: 2
期刊
Journal of Future Foods
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