Pub Date : 2024-09-20DOI: 10.1016/j.cclet.2024.110478
Wu-Yang Liu , Xin-Xiang Lei , Wen-Ji Wang , Jun-Mian Tian , Yu-Qi Gao , Jin-Ming Gao
Hyperforatone A (1), the 1,8-seco rearranged polycyclic polyprenylated acylphloroglucinol, possessed an unusual bicyclo[5.4.0]undecane skeleton bearing a 5/7/6/5 ring system, and two known biosynthetically related precursors (2 and 3) were isolated from Hypericum perforatum (St. John's wort). The structure and absolute configuration were unambiguously confirmed by a combination of comprehensive spectroscopic data, computational methods including residual dipolar couplings (RDCs), and X-ray crystallography. Density functional theory (DFT) calculations revealed that the cationic cyclization reaction was key to proposed formation mechanism for hyperforatone A. Furthermore, in vitro and in vivo experiments demonstrated that compound 1 was a potential anti-neuroinflammatory agent.
{"title":"Hyperforatone A, the 1,8-seco rearranged polycyclic polyprenylated acylphloroglucinol with a unique bicyclo[5.4.0]undecane core from Hypericum perforatum","authors":"Wu-Yang Liu , Xin-Xiang Lei , Wen-Ji Wang , Jun-Mian Tian , Yu-Qi Gao , Jin-Ming Gao","doi":"10.1016/j.cclet.2024.110478","DOIUrl":"10.1016/j.cclet.2024.110478","url":null,"abstract":"<div><div>Hyperforatone A (<strong>1</strong>), the 1,8-<em>seco</em> rearranged polycyclic polyprenylated acylphloroglucinol, possessed an unusual bicyclo[5.4.0]undecane skeleton bearing a 5/7/6/5 ring system, and two known biosynthetically related precursors (<strong>2</strong> and <strong>3</strong>) were isolated from <em>Hypericum perforatum</em> (St. John's wort). The structure and absolute configuration were unambiguously confirmed by a combination of comprehensive spectroscopic data, computational methods including residual dipolar couplings (RDCs), and X-ray crystallography. Density functional theory (DFT) calculations revealed that the cationic cyclization reaction was key to proposed formation mechanism for hyperforatone A. Furthermore, <em>in vitro</em> and <em>in vivo</em> experiments demonstrated that compound <strong>1</strong> was a potential anti-neuroinflammatory agent.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 4","pages":"Article 110478"},"PeriodicalIF":9.4,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-20DOI: 10.1016/j.cclet.2024.110477
Mohamed Saber Lassoued , Faizan Ahmad , Yanzhen Zheng
Lead-free hybrid double perovskites (LFHDPs) have received a lot of attention due to their environmental friendliness and promising attributes. However, studying the effect of film thickness on LFHDPs optoelectronic properties has not yet been investigated. Herein, we synthesized two new Ruddlesden–Popper LFHDPs, namely (C5H12N)4AgBiI8 (CAB-1) and (C6H14N)4AgBiI8 (CAB-2) using cyclopentylamine and cyclohexylamine as monoamine ligands. Indeed, these two Ag(I)-Bi(III) LFHDPs form smooth and uniform films ranging in thickness from 250 nm to 1 μm, with preferred orientations. Notably, the studies on the optical properties showed that the direct band gap value decreased from 2.17 eV to 1.91 eV for CAB-1 and from 2.05 eV to 1.86 eV for CAB-2 with increasing thickness. Accordingly, photo-current response using a xenon lamp revealed a significant difference of over 1000 nA between light and dark conditions for 1 μm-thickness films, suggesting potential for light harvesting. Other than that, thicker films of CAB-1 and CAB-2 exhibit high stability for 90 days in a relatively humid environment (RH of 55 %), paving the way for promising optoelectronic applications.
{"title":"Film thickness effect on 2D lead-free hybrid double perovskite properties: Band gap, photocurrent and stability","authors":"Mohamed Saber Lassoued , Faizan Ahmad , Yanzhen Zheng","doi":"10.1016/j.cclet.2024.110477","DOIUrl":"10.1016/j.cclet.2024.110477","url":null,"abstract":"<div><div>Lead-free hybrid double perovskites (LFHDPs) have received a lot of attention due to their environmental friendliness and promising attributes. However, studying the effect of film thickness on LFHDPs optoelectronic properties has not yet been investigated. Herein, we synthesized two new Ruddlesden–Popper LFHDPs, namely (C<sub>5</sub>H<sub>12</sub>N)<sub>4</sub>AgBiI<sub>8</sub> (CAB-1) and (C<sub>6</sub>H<sub>14</sub>N)<sub>4</sub>AgBiI<sub>8</sub> (CAB-2) using cyclopentylamine and cyclohexylamine as monoamine ligands. Indeed, these two Ag(I)-Bi(III) LFHDPs form smooth and uniform films ranging in thickness from 250 nm to 1 μm, with preferred orientations. Notably, the studies on the optical properties showed that the direct band gap value decreased from 2.17 eV to 1.91 eV for CAB-1 and from 2.05 eV to 1.86 eV for CAB-2 with increasing thickness. Accordingly, photo-current response using a xenon lamp revealed a significant difference of over 1000 nA between light and dark conditions for 1 μm-thickness films, suggesting potential for light harvesting. Other than that, thicker films of CAB-1 and CAB-2 exhibit high stability for 90 days in a relatively humid environment (RH of 55 %), paving the way for promising optoelectronic applications.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 4","pages":"Article 110477"},"PeriodicalIF":9.4,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143098705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-19DOI: 10.1016/j.cclet.2024.110476
Sanmei Wang , Yong Zhou , Hengxin Fang , Chunyang Nie , Chang Q Sun , Biao Wang
Charge-neutral method (CNM) is extensively used in investigating the performance of catalysts and the mechanism of N2 electrochemical reduction (NRR). However, disparities remain between the predicted potentials required for NRR by the CNM methods and those observed experimentally, as the CNM method neglects the charge effect from the electrode potential. To address this issue, we employed the constant electrode potential (CEP) method to screen atomic transition metal-N-graphene (M1/N-graphene) as NRR electrocatalysts and systematically investigated the underlying catalytic mechanism. Among eight types of M1/N-graphene (M1 = Mo, W, Fe, Re, Ni, Co, V, Cr), W1/N-graphene emerges as the most promising NRR electrocatalyst with a limiting potential as low as −0.13 V. Additionally, the W1/N-graphene system consistently maintains a positive charge during the reaction due to its Fermi level being higher than that of the electrode. These results better match with the actual circumstances compared to those calculated by conventional CNM method. Thus, our work not only develops a promising electrocatalyst for NRR but also deepens the understanding of the intrinsic electrocatalytic mechanism.
{"title":"Constant-potential simulation of electrocatalytic N2 reduction over atomic metal-N-graphene catalysts","authors":"Sanmei Wang , Yong Zhou , Hengxin Fang , Chunyang Nie , Chang Q Sun , Biao Wang","doi":"10.1016/j.cclet.2024.110476","DOIUrl":"10.1016/j.cclet.2024.110476","url":null,"abstract":"<div><div>Charge-neutral method (CNM) is extensively used in investigating the performance of catalysts and the mechanism of N<sub>2</sub> electrochemical reduction (NRR). However, disparities remain between the predicted potentials required for NRR by the CNM methods and those observed experimentally, as the CNM method neglects the charge effect from the electrode potential. To address this issue, we employed the constant electrode potential (CEP) method to screen atomic transition metal-N-graphene (M<sub>1</sub>/N-graphene) as NRR electrocatalysts and systematically investigated the underlying catalytic mechanism. Among eight types of M<sub>1</sub>/N-graphene (M<sub>1</sub> = Mo, W, Fe, Re, Ni, Co, V, Cr), W<sub>1</sub>/N-graphene emerges as the most promising NRR electrocatalyst with a limiting potential as low as −0.13 V. Additionally, the W<sub>1</sub>/N-graphene system consistently maintains a positive charge during the reaction due to its Fermi level being higher than that of the electrode. These results better match with the actual circumstances compared to those calculated by conventional CNM method. Thus, our work not only develops a promising electrocatalyst for NRR but also deepens the understanding of the intrinsic electrocatalytic mechanism.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 3","pages":"Article 110476"},"PeriodicalIF":9.4,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143356835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-18DOI: 10.1016/j.cclet.2024.110469
Jia-Cheng Hou , Wei Cai , Hong-Tao Ji , Li-Juan Ou , Wei-Min He
Semi-heterogeneous photocatalysis has emerged as a powerful and productive platform in organic chemistry, which provides mild and eco-friendly conditions for a diverse range of bond-forming reactions. The synergy of homogeneous catalysts and heterogeneous catalysts inherits their main advantages, such as higher activities, easy separation and superior recyclability. In this review, we summarize the recent advances in recyclable semi-heterogenous protocols for the light promoted bond-forming reactions and identify directions for future research according to the different photocatalysts/metal/redox catalysts involved. Notably, this review is not a comprehensive description of reported literature but aim to highlight and illustrate key concepts, strategies, reaction model, reaction conditions and mechanisms.
{"title":"Recent advances in semi-heterogenous photocatalysis in organic synthesis","authors":"Jia-Cheng Hou , Wei Cai , Hong-Tao Ji , Li-Juan Ou , Wei-Min He","doi":"10.1016/j.cclet.2024.110469","DOIUrl":"10.1016/j.cclet.2024.110469","url":null,"abstract":"<div><div>Semi-heterogeneous photocatalysis has emerged as a powerful and productive platform in organic chemistry, which provides mild and eco-friendly conditions for a diverse range of bond-forming reactions. The synergy of homogeneous catalysts and heterogeneous catalysts inherits their main advantages, such as higher activities, easy separation and superior recyclability. In this review, we summarize the recent advances in recyclable semi-heterogenous protocols for the light promoted bond-forming reactions and identify directions for future research according to the different photocatalysts/metal/redox catalysts involved. Notably, this review is not a comprehensive description of reported literature but aim to highlight and illustrate key concepts, strategies, reaction model, reaction conditions and mechanisms.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 2","pages":"Article 110469"},"PeriodicalIF":9.4,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-17DOI: 10.1016/j.cclet.2024.109881
Donghui Wu , Qilin Zhao , Jian Sun , Xiurong Yang
{"title":"Corrigendum to ‘Fluorescence immunoassay based on alkaline phosphatase-induced in situ generation of fluorescent non-conjugated polymer dots’ [Chinese Chemical Letters 34 (2023) 107672]","authors":"Donghui Wu , Qilin Zhao , Jian Sun , Xiurong Yang","doi":"10.1016/j.cclet.2024.109881","DOIUrl":"10.1016/j.cclet.2024.109881","url":null,"abstract":"","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"35 12","pages":"Article 109881"},"PeriodicalIF":9.4,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1001841724004005/pdfft?md5=f3cecc8fadb9300fd3929e88c49fd498&pid=1-s2.0-S1001841724004005-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142241276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-16DOI: 10.1016/j.cclet.2024.110466
Huiju Cao, Lei Shi
Carbon materials have long been a subject of study, offering diverse properties based on their hybridized structures. Except sp2-hybridized graphene and carbon nanotubes, the focus on sp1-hybridized carbon chains has garnered significant interest due to its unique predicted properties, despite limitations in research and development stemming from its high reactivity. This comprehensive review summaries recent advancements in synthetic methodologies and characterization of the sp1-hybridized carbon chains, encompassing linear carbon chains and cyclo[n]carbons. The review traces significant milestones in synthesis and offers a thorough overview of various properties on linear and cyclic carbon chains, from their initial discovery to recent development. The advancing synthetic methods have led to practical breakthroughs, transitioning theoretical concepts into tangible carbon-chain materials. However, challenges persist in achieving controlled and scalable preparation due to the high reactivity associated with sp1-hybridization. Future research prospects focus on fundamental studies, such as exploring the transition length from polyyne to carbyne and experimentally determining the properties of single carbon chains. This review underscores both the progress made and the compelling avenues for future exploration in the dynamic field of sp1-hybridized carbon chains.
{"title":"Sp1-hybridized linear and cyclic carbon chain","authors":"Huiju Cao, Lei Shi","doi":"10.1016/j.cclet.2024.110466","DOIUrl":"10.1016/j.cclet.2024.110466","url":null,"abstract":"<div><div>Carbon materials have long been a subject of study, offering diverse properties based on their hybridized structures. Except sp<sup>2</sup>-hybridized graphene and carbon nanotubes, the focus on sp<sup>1</sup>-hybridized carbon chains has garnered significant interest due to its unique predicted properties, despite limitations in research and development stemming from its high reactivity. This comprehensive review summaries recent advancements in synthetic methodologies and characterization of the sp<sup>1</sup>-hybridized carbon chains, encompassing linear carbon chains and cyclo[<em>n</em>]carbons. The review traces significant milestones in synthesis and offers a thorough overview of various properties on linear and cyclic carbon chains, from their initial discovery to recent development. The advancing synthetic methods have led to practical breakthroughs, transitioning theoretical concepts into tangible carbon-chain materials. However, challenges persist in achieving controlled and scalable preparation due to the high reactivity associated with sp<sup>1</sup>-hybridization. Future research prospects focus on fundamental studies, such as exploring the transition length from polyyne to carbyne and experimentally determining the properties of single carbon chains. This review underscores both the progress made and the compelling avenues for future exploration in the dynamic field of sp<sup>1</sup>-hybridized carbon chains.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 4","pages":"Article 110466"},"PeriodicalIF":9.4,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143098170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-15DOI: 10.1016/j.cclet.2024.110468
Yue Ren , Kang Li , Yi-Zi Wang , Shao-Peng Zhao , Shu-Min Pan , Haojie Fu , Mengfan Jing , Yaming Wang , Fengyuan Yang , Chuntai Liu
The considerable hazard posed by periprosthetic joint infections underlines the urgent need for the rapid advancement of in-situ drug delivery systems within joint materials. However, the pursuit of sustained antibacterial efficacy remains a formidable challenge. In this context, we proposed a novel strategy that leverages swelling and erosion mechanisms to facilitate drug release of drug-loaded ultrahigh molecular weight polyethylene (UHMWPE), thereby ensuring its long-lasting antibacterial performance. Polyethylene oxide (PEO), a hydrophilic polymer with fast hydrating ability and high swelling capacity, was incorporated in UHMWPE alongside the antibacterial tea polyphenol (epigallocatechin gallate, EGCG as representative). The swelling of PEO enhanced water infiltration into the matrix, while the erosion of PEO balanced the release of the encapsulated EGCG, resulting in a steady release. The behavior was supported by the EGCG release profiles and the corresponding fitted release kinetic models. As demonstrated by segmented antibacterial assessments, the antibacterial efficiency was enhanced 2 to 3 times in the PEO/EGCG/UHMWPE composite compared to that of EGCG/UHMWPE. Additionally, the PEO/EGCG/UHMWPE composite exhibited favorable biocompatibility and mechanical performance, making it a potential candidate for the development of drug-releasing joint implants to combat prosthetic bacterial infections.
{"title":"Swelling and erosion assisted sustained release of tea polyphenol from antibacterial ultrahigh molecular weight polyethylene for joint replacement","authors":"Yue Ren , Kang Li , Yi-Zi Wang , Shao-Peng Zhao , Shu-Min Pan , Haojie Fu , Mengfan Jing , Yaming Wang , Fengyuan Yang , Chuntai Liu","doi":"10.1016/j.cclet.2024.110468","DOIUrl":"10.1016/j.cclet.2024.110468","url":null,"abstract":"<div><div>The considerable hazard posed by periprosthetic joint infections underlines the urgent need for the rapid advancement of <em>in-situ</em> drug delivery systems within joint materials. However, the pursuit of sustained antibacterial efficacy remains a formidable challenge. In this context, we proposed a novel strategy that leverages swelling and erosion mechanisms to facilitate drug release of drug-loaded ultrahigh molecular weight polyethylene (UHMWPE), thereby ensuring its long-lasting antibacterial performance. Polyethylene oxide (PEO), a hydrophilic polymer with fast hydrating ability and high swelling capacity, was incorporated in UHMWPE alongside the antibacterial tea polyphenol (epigallocatechin gallate, EGCG as representative). The swelling of PEO enhanced water infiltration into the matrix, while the erosion of PEO balanced the release of the encapsulated EGCG, resulting in a steady release. The behavior was supported by the EGCG release profiles and the corresponding fitted release kinetic models. As demonstrated by segmented antibacterial assessments, the antibacterial efficiency was enhanced 2 to 3 times in the PEO/EGCG/UHMWPE composite compared to that of EGCG/UHMWPE. Additionally, the PEO/EGCG/UHMWPE composite exhibited favorable biocompatibility and mechanical performance, making it a potential candidate for the development of drug-releasing joint implants to combat prosthetic bacterial infections.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 2","pages":"Article 110468"},"PeriodicalIF":9.4,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-15DOI: 10.1016/j.cclet.2024.110467
Bowen Li, Ting Wang, Ming Xu, Yuqi Wang, Zhaoxing Li, Mei Liu, Wenjing Zhang, Ming Feng
Improving the surface atoms utilization efficiency of catalysts is extremely important for large-scale H2 production by electrochemical water splitting, but it remains a great challenge. Herein, we reported two kinds of MoO3-polyoxometalate hybrid nanobelt superstructures (MoO3-POM HNSs, POM = PW12O40 and SiW12O40) using a simple hydrothermal method. Such superstructure with highly uniform nanoparticles as building blocks can expose more surface atoms and emanate increased specific surface area. The incorporated POMs generated abundant oxygen vacancies, improved the electronic mobility, and modulated the surface electronic structure of MoO3, allowing to optimize the H* adsorption/desorption and dehydrogenation kinetics of catalyst. Notably, the as-prepared MoO3-PW12O40 HNSs electrodes not only displayed the low overpotentials of 108 mV at 10 mA/cm2 current density in 0.5 mol/L H2SO4 electrolyte but also displayed excellent long-term stability. The hydrogen evolution reaction (HER) performance of MoO3-POM superstructures is significantly better than that of corresponding bulk materials MoO3@PW12O40 and MoO3@SiW12O40, and the overpotentials are about 8.3 and 4.9 times lower than that of single MoO3. This work opens an avenue for designing highly surface-exposed catalysts for electrocatalytic H2 production and other electrochemical applications.
{"title":"Structuring MoO3-polyoxometalate hybrid superstructures to boost electrocatalytic hydrogen evolution reaction","authors":"Bowen Li, Ting Wang, Ming Xu, Yuqi Wang, Zhaoxing Li, Mei Liu, Wenjing Zhang, Ming Feng","doi":"10.1016/j.cclet.2024.110467","DOIUrl":"10.1016/j.cclet.2024.110467","url":null,"abstract":"<div><div>Improving the surface atoms utilization efficiency of catalysts is extremely important for large-scale H<sub>2</sub> production by electrochemical water splitting, but it remains a great challenge. Herein, we reported two kinds of MoO<sub>3</sub>-polyoxometalate hybrid nanobelt superstructures (MoO<sub>3</sub>-POM HNSs, POM = PW<sub>12</sub>O<sub>40</sub> and SiW<sub>12</sub>O<sub>40</sub>) using a simple hydrothermal method. Such superstructure with highly uniform nanoparticles as building blocks can expose more surface atoms and emanate increased specific surface area. The incorporated POMs generated abundant oxygen vacancies, improved the electronic mobility, and modulated the surface electronic structure of MoO<sub>3</sub>, allowing to optimize the H* adsorption/desorption and dehydrogenation kinetics of catalyst. Notably, the as-prepared MoO<sub>3</sub>-PW<sub>12</sub>O<sub>40</sub> HNSs electrodes not only displayed the low overpotentials of 108 mV at 10 mA/cm<sup>2</sup> current density in 0.5 mol/L H<sub>2</sub>SO<sub>4</sub> electrolyte but also displayed excellent long-term stability. The hydrogen evolution reaction (HER) performance of MoO<sub>3</sub>-POM superstructures is significantly better than that of corresponding bulk materials MoO<sub>3</sub>@PW<sub>12</sub>O<sub>40</sub> and MoO<sub>3</sub>@SiW<sub>12</sub>O<sub>40</sub>, and the overpotentials are about 8.3 and 4.9 times lower than that of single MoO<sub>3</sub>. This work opens an avenue for designing highly surface-exposed catalysts for electrocatalytic H<sub>2</sub> production and other electrochemical applications.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 2","pages":"Article 110467"},"PeriodicalIF":9.4,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-14DOI: 10.1016/j.cclet.2024.110462
Ali Dai , Zhiguo Zheng , Liusheng Duan , Jian Wu , Weiming Tan
Agrochemicals, especially plant growth regulators (PGRs), are extensively used to modulate endogenous phytohormone signals in small quantities, significantly influencing plant growth and development. Plant hormones typically exhibit diverse chemical structures, with common examples including indole rings, terpenoid frameworks, adenine motifs, cyclic lactones, cyclopentanones, and steroidal compounds, which are extensively employed in pesticides. This article explores the interactions and biological activities of small molecules on proteins, enzymes, and other reactive sites involved in the biosynthesis, metabolism, transport, and signal transduction pathways of various plant hormones. Additionally, it analyzes the structure-activity relationships (SARs) of pesticides incorporating these structural motifs to elucidate the relationship between active fragments, pharmacophores, and targets, highlighting the characteristics of potent small molecules and their derivatives. This comprehensive review aims to provide novel perspectives for the development and design of pesticides, offering valuable insights for researchers in the field.
{"title":"Small molecule chemical scaffolds in plant growth regulators for the development of agrochemicals","authors":"Ali Dai , Zhiguo Zheng , Liusheng Duan , Jian Wu , Weiming Tan","doi":"10.1016/j.cclet.2024.110462","DOIUrl":"10.1016/j.cclet.2024.110462","url":null,"abstract":"<div><div>Agrochemicals, especially plant growth regulators (PGRs), are extensively used to modulate endogenous phytohormone signals in small quantities, significantly influencing plant growth and development. Plant hormones typically exhibit diverse chemical structures, with common examples including indole rings, terpenoid frameworks, adenine motifs, cyclic lactones, cyclopentanones, and steroidal compounds, which are extensively employed in pesticides. This article explores the interactions and biological activities of small molecules on proteins, enzymes, and other reactive sites involved in the biosynthesis, metabolism, transport, and signal transduction pathways of various plant hormones. Additionally, it analyzes the structure-activity relationships (SARs) of pesticides incorporating these structural motifs to elucidate the relationship between active fragments, pharmacophores, and targets, highlighting the characteristics of potent small molecules and their derivatives. This comprehensive review aims to provide novel perspectives for the development and design of pesticides, offering valuable insights for researchers in the field.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 4","pages":"Article 110462"},"PeriodicalIF":9.4,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-14DOI: 10.1016/j.cclet.2024.110446
Min-Hang Zhou, Jun Jiang, Wei-Min He
{"title":"EDA-complexes-enabled photochemical synthesis of α-amino acids with imines and tetrabutylammonium oxalate","authors":"Min-Hang Zhou, Jun Jiang, Wei-Min He","doi":"10.1016/j.cclet.2024.110446","DOIUrl":"10.1016/j.cclet.2024.110446","url":null,"abstract":"","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 1","pages":"Article 110446"},"PeriodicalIF":9.4,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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