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Adhesion of Candida albicans on PTFE membranes used in guided bone regeneration 白色念珠菌在用于引导骨再生的聚四氟乙烯膜上的粘附。
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-16 DOI: 10.1002/cre2.902
Adel Al-Asfour, Maribasappa Karched, Syed Saad Bin Qasim, Gregor-Georg Zafiropoulos

Objectives

Guided bone regeneration (GBR) is a core procedure used to regenerate bone defects. The aim of the study was to investigate the adherence of Candida albicans on six commercially available polytetrafluoroethylene (PTFE) membranes used in GBR procedures and the subsequent clinical consequences.

Materials and Methods

Six commercially available PTFE membranes were tested. Two of the membranes had a textured surface and the other four a plane, nontextured one. C. albicans (ATCC 24433) was cultured for 24 h, and its cell surface hydrophobicity was assessed using a modified method. C. albicans adhesion to membrane discs was studied by scanning electron microscopy (SEM) and real-time polymerase chain reaction (PCR).

Results

C. albicans was found to be hydrophobic (77.25%). SEM analysis showed that C. albicans adherence to all membranes examined was characterized by patchy, scattered, and small clustered patterns except for one nontextured membrane with a most rough surface in which a thick biofilm was observed. Real-time PCR quantification revealed significantly greater adhesion of C. albicans cells to PTFE membranes than the control membrane (p ≤ .001) with the membranes having a textured surface exhibiting the highest count of 2680 × 104 cells/ml compared to the count of 707 × 104 cells/mL on those with a nontextured one (p ≤ .001). One membrane with nontextured surface, but with most rough surface was found to exhibit the highest count of 3010 × 104 cells/ml (p ≤ .05).

Conclusion

The results of this study indicate that C. albicans adhesion on membranes' surfaces depends on the degree of surface roughness and/or on the presence of a texture. Textured PTFE membranes and/or membranes high roughness showed significantly more adhered C. albicans cells. These findings can impact the surgeon's choice of GBR membrane and postoperative maintenance.

目的:引导骨再生(GBR)是用于骨缺损再生的核心程序。本研究旨在调查白念珠菌在 GBR 程序中使用的六种市售聚四氟乙烯(PTFE)膜上的附着情况以及随后的临床后果:测试了六种市售聚四氟乙烯膜。材料:对六种市售聚四氟乙烯膜进行了测试,其中两种膜的表面有纹理,另外四种膜的表面平整无纹理。将白僵菌(ATCC 24433)培养 24 小时后,使用改进的方法评估其细胞表面疏水性。通过扫描电子显微镜(SEM)和实时聚合酶链反应(PCR)研究了白僵菌对膜盘的粘附情况:结果:发现白僵菌具有疏水性(77.25%)。扫描电镜分析表明,白僵菌粘附在所有受检膜上的特点是斑块状、分散状和小团块状,只有一种表面最粗糙的无纹理膜上出现了厚厚的生物膜。实时 PCR 定量显示,白僵菌细胞在聚四氟乙烯膜上的附着力明显高于对照膜(p ≤ .001),表面有纹理的膜上的细胞数最高,为 2680 × 104 个/毫升,而表面无纹理的膜上的细胞数为 707 × 104 个/毫升(p ≤ .001)。发现表面无纹理但最粗糙的一层膜的细胞数最多,达到 3010 × 104 个/毫升(p ≤ .05):本研究结果表明,白僵菌在膜表面的粘附取决于表面粗糙度和/或纹理的存在。有纹理的聚四氟乙烯膜和/或高粗糙度膜上粘附的白僵菌细胞明显较多。这些发现会影响外科医生对 GBR 膜的选择和术后维护。
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引用次数: 0
A Cross-Sectional Survey of the Use of Clear Aligners by General Dentists in Australia 澳大利亚普通牙医使用透明矫治器情况的横断面调查。
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-07 DOI: 10.1002/cre2.919
Maurice J. Meade, Tony Weir

Objectives

The primary aim of the investigation was to survey clear aligner therapy (CAT) use among general dentists in Australia. A secondary aim was to evaluate the factors that influenced general dentists in Australia not to provide CAT.

Material and Methods

General dentists registered with the Australian Health Practitioner Regulation Agency were invited to participate in a structured cross-sectional electronic survey. The survey covered demographics, preferred CAT systems and practices, relevant treatment planning and retention protocols, patient-reported CAT issues, pertinent respondent opinions, and reasons for not providing CAT. Descriptive statistics were computed via GraphPad Prism v10 (GraphPad Software Inc., La Jolla, CA, USA).

Results

Most of the 264 (n = 172; 65.2%) respondents indicated that they provided CAT. The majority (n = 82; 58.6%) reported that they treated between 1 and 20 patients with CAT annually. Invisalign was the most used system (n = 83; 61.2%), with 55 (41.7%), indicating that they used more than one system. Most (n = 124; 98.4%) were comfortable using CAT for mild crowding, whereas 73.4% (n = 94) were not comfortable in treating severe crowding with CAT. The median (IQR) number of patients per respondent treated with extraction of a permanent incisor or premolar was 0 (0). Issues regarding tooth positions were reportedly always or mostly in need of change in the initial treatment plan by 68.7%. Problems regarding patient compliance with CAT wear protocols (n = 67; 45.6%) and the predictability of treatment outcomes (n = 31; 21.1%) were the most identified themes of the free-text comments. Over 80% of those who did not provide CAT indicated that they preferred to refer to an orthodontist for management.

Conclusion

Almost two-thirds of the respondents provided CAT. Invisalign was the most used system. The majority use CAT combined with nonextraction treatment. Most of those who did not provide CAT preferred to refer to an orthodontist for patient management.

目的:调查的主要目的是调查澳大利亚普通牙医使用透明矫治器疗法(CAT)的情况。次要目的是评估影响澳大利亚普通牙医不提供CAT的因素:我们邀请在澳大利亚卫生从业者监管局注册的普通牙医参与一项结构化横截面电子调查。调查内容包括人口统计学、首选的 CAT 系统和实践、相关治疗计划和保留方案、患者报告的 CAT 问题、受访者的相关意见以及不提供 CAT 的原因。通过 GraphPad Prism v10(GraphPad Software Inc:264 位受访者中的大多数(n = 172;65.2%)表示他们提供了 CAT。大多数受访者(n = 82;58.6%)表示,他们每年用 CAT 治疗 1 到 20 名患者。隐适美是使用最多的系统(n = 83;61.2%),有 55 人(41.7%)表示他们使用了一种以上的系统。大多数患者(n = 124;98.4%)愿意使用 CAT 治疗轻度拥挤,而 73.4% 的患者(n = 94)不愿意使用 CAT 治疗严重拥挤。每位受访者接受拔除恒切牙或前磨牙治疗的患者人数中位数(IQR)为 0(0)。68.7%的受访者表示,在最初的治疗方案中,总是或大部分需要改变牙齿位置的问题。自由文本评论中最常见的主题是患者对 CAT 佩戴方案的依从性问题(67 人,占 45.6%)和治疗结果的可预测性问题(31 人,占 21.1%)。超过 80% 不提供 CAT 的受访者表示,他们更愿意转诊给正畸医生进行治疗:近三分之二的受访者提供了 CAT。隐适美是使用最多的系统。大多数受访者在使用计算机辅助矫正的同时,还使用非拔牙治疗。大多数不提供计算机辅助矫正的受访者倾向于将患者转介给正畸医生进行管理。
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引用次数: 0
The Impact of the COVID-19 Pandemic on Pattern of Antibiotic and Opioid Prescriptions by Dentists in Alberta, Canada COVID-19 大流行对加拿大艾伯塔省牙医开具抗生素和阿片类药物处方模式的影响。
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-07 DOI: 10.1002/cre2.913
Riley Immel, Babak Bohlouli, Maryam Amin

Objectives

After the shutdown of most dental services during the COVID-19 lockdown, the oral health community was concerned about an increase in prescribing opioids and antibiotics by dentists due to patients' limited access to dental offices. Therefore, the objective of this study was to investigate the impact of COVID-19 pandemic on the pattern of antibiotic and opioid prescriptions by dentists in Alberta, Canada.

Methods

Data obtained from the Tracked Prescription Program were divided into antibiotics and opioids. Time periods were outlined as pre-, during-, and postlockdown (phase 1 and 2). For the number of prescriptions and average supply, each monthly average was compared to the corresponding prelockdown monthly average, using descriptive analysis. Time series analyses were conducted using regression analyses with an autoregressive error model. Data were trained and tested on monthly observations before lockdown and predicted for during- and postlockdown.

Results

A total of 1.1 million antibiotics and 400,000 opioids dispense were tracked. Decreases in the number of prescriptions during lockdown presented for antibiotics (n = 24,933 vs. 18,884) and opioids (n = 8892 vs. 6051). Average supplies (days) for the antibiotics (n = 7.10 vs. 7.55) and opioids (n = 3.92 vs. 4.05) were higher during the lockdown period. In the trend analyses, the monthly number of antibiotic and opioid prescriptions showed the same pattern and decreased during lockdown.

Conclusion

The COVID-19 pandemic altered the trends of prescribing antibiotics and opioids by dentists. The full impact of COVID-19 pandemic on the population's oral health in light of changes in prescribing practices by dentists during and after lockdown warrants further investigation.

目标:在 COVID-19 封锁期间大多数牙科服务被关闭后,口腔健康界担心由于患者前往牙科诊所的机会有限,牙医开具阿片类药物和抗生素处方的情况会增加。因此,本研究旨在调查 COVID-19 大流行对加拿大艾伯塔省牙医开具抗生素和阿片类药物处方模式的影响:方法:从跟踪处方计划获得的数据分为抗生素和阿片类药物。时间段分为封锁前、封锁期间和封锁后(第一和第二阶段)。对于处方数量和平均供应量,采用描述性分析方法将每个月的平均值与封锁前的相应月平均值进行比较。时间序列分析采用自回归误差模型进行回归分析。对封锁前的每月观测数据进行了训练和测试,并对封锁期间和封锁后的数据进行了预测:共跟踪了 110 万份抗生素和 40 万份阿片类药物的配药情况。在封锁期间,抗生素(n = 24,933 对 18,884 )和阿片类药物(n = 8892 对 6051)的处方数量均有所减少。在封锁期间,抗生素(n = 7.10 对 7.55)和阿片类药物(n = 3.92 对 4.05)的平均供应量(天数)较高。在趋势分析中,每月的抗生素和阿片类药物处方数量显示出相同的模式,并在封锁期间有所下降:COVID-19大流行改变了牙医开具抗生素和阿片类药物处方的趋势。根据封锁期间和封锁后牙医处方做法的变化,COVID-19 大流行对人口口腔健康的全面影响值得进一步研究。
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引用次数: 0
Oronasal Fistula Closure and Defect Reconstruction: Two Case Reports Using Periodontal Plastic Surgery Principles 口鼻瘘管闭合和缺损重建:利用牙周整形原理的两个病例报告。
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-07 DOI: 10.1002/cre2.914
Gerardo Chacon, Abdusalam Alrmali, Obada Mandil, Héctor Rodriguez, José Rodriguez, Anas Al-misurati, Hom-Lay Wang

Objectives

Oronasal fistulas are common sequelae following cleft lip and palate surgery and can significantly impact a patient's quality of life. They result from various factors, including surgical techniques, tissue management, and patient-specific factors. This case report explores the modern approach to oronasal fistula closure using periodontal plastic surgery principles.

Materials and Methods

The report presents two cases of patients with oronasal fistulas due to previous maxillofacial surgical intervention. These patients underwent microsurgical procedures that involved partial flap thickness preparation of the fistula areas, the use of connective tissue grafts from the palate, and meticulous suturing techniques to ensure graft integrity. The procedures were performed in stages, and postoperative care was provided.

Results

Both cases demonstrated successful fistula closure and graft survival. The patients reported improvements in breathing, speech, aesthetics, and quality of life. The second case also included guided bone regeneration and implant placement.

Conclusions

Oronasal fistulas resulting from maxillofacial surgery can be effectively treated using periodontal plastic surgery techniques, significantly improving patients' quality of life and aesthetic outcomes. This approach represents a valuable addition to the existing repertoire of oronasal fistula closure methods.

目的:口鼻瘘是唇腭裂手术后常见的后遗症,会严重影响患者的生活质量。造成口鼻瘘的因素多种多样,包括手术技术、组织管理和患者特异性因素。本病例报告探讨了利用牙周整形外科原理进行口瘘闭合的现代方法:本报告介绍了两例因既往颌面外科手术干预而导致口鼻瘘的患者。这些患者接受了显微外科手术,包括瘘管部位的部分皮瓣厚度准备、腭结缔组织移植物的使用以及确保移植物完整性的细致缝合技术。手术分阶段进行,并提供术后护理:结果:两个病例均成功闭合瘘管,移植物存活。结果:两个病例都成功关闭了瘘管,移植物存活,患者的呼吸、言语、美观和生活质量都有所改善。第二个病例还包括引导骨再生和种植体植入:结论:利用牙周整形技术可以有效治疗颌面外科手术导致的口瘘,显著改善患者的生活质量和美观效果。这种方法是对现有口瘘闭合方法的重要补充。
{"title":"Oronasal Fistula Closure and Defect Reconstruction: Two Case Reports Using Periodontal Plastic Surgery Principles","authors":"Gerardo Chacon,&nbsp;Abdusalam Alrmali,&nbsp;Obada Mandil,&nbsp;Héctor Rodriguez,&nbsp;José Rodriguez,&nbsp;Anas Al-misurati,&nbsp;Hom-Lay Wang","doi":"10.1002/cre2.914","DOIUrl":"10.1002/cre2.914","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Oronasal fistulas are common sequelae following cleft lip and palate surgery and can significantly impact a patient's quality of life. They result from various factors, including surgical techniques, tissue management, and patient-specific factors. This case report explores the modern approach to oronasal fistula closure using periodontal plastic surgery principles.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>The report presents two cases of patients with oronasal fistulas due to previous maxillofacial surgical intervention. These patients underwent microsurgical procedures that involved partial flap thickness preparation of the fistula areas, the use of connective tissue grafts from the palate, and meticulous suturing techniques to ensure graft integrity. The procedures were performed in stages, and postoperative care was provided.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Both cases demonstrated successful fistula closure and graft survival. The patients reported improvements in breathing, speech, aesthetics, and quality of life. The second case also included guided bone regeneration and implant placement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Oronasal fistulas resulting from maxillofacial surgery can be effectively treated using periodontal plastic surgery techniques, significantly improving patients' quality of life and aesthetic outcomes. This approach represents a valuable addition to the existing repertoire of oronasal fistula closure methods.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11228353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation Between Implant Stability Quotient and Percussion Sound Frequency 种植体稳定性商数与叩击声频率之间的相关性
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-07 DOI: 10.1002/cre2.917
Wansiri Peeraprasompong, Weerapan Aunmeungtong, Pathawee Khongkhunthian

Objectives

To determine the correlation between the primary implant stability quotient and the implant percussion sound frequency.

Materials and Methods

A total of 14 pigs' ribs were scanned using a dental cone beam computed tomography (CBCT) scanner to classify the bone specimens into three distinct bone density Hounsfield units (HU) value categories: D1 bone: >1250 HU; D2: 850–1250 HU; D3: <850 HU. Then, 96 implants were inserted: 32 implants in D1 bone, 32 implants in D2 bone, and 32 implants in D3 bone. The primary implant stability quotient (ISQ) was analyzed, and percussion sound was recorded using a wireless microphone connected and analyzed with frequency analysis software.

Results

Statistically significant positive correlations were found between the primary ISQ and the bone density HU value (r = 0.719; p < 0.001), and statistically significant positive correlations between the primary ISQ and the percussion sound frequency (r = 0.606; p < 0.001). Furthermore, significant differences in primary ISQ values and percussion sound frequency were found between D1 and D2 bone, as well as between D1 and D3 bone. However, no significant differences were found in primary ISQ values and percussion sound frequency between D2 and D3 bone.

Conclusion

The primary ISQ value and the percussion sound frequency are positively correlated.

目的:确定主要种植体稳定性商数与种植体叩击声频率之间的相关性:确定主要种植体稳定性商数与种植体叩击声频率之间的相关性:使用牙科锥形束计算机断层扫描(CBCT)扫描仪对总共 14 根猪肋骨进行扫描,将骨标本分为三个不同的骨密度 Hounsfield 单位(HU)值类别:D1 骨:>1250 HU;D2:850-1250 HU;D3:850-1250 HU:结果主要 ISQ 值与骨密度 HU 值之间存在统计学意义上的明显正相关(r = 0.719;p 结论:主要 ISQ 值与骨密度 HU 值之间存在统计学意义上的明显正相关:原发性 ISQ 值与叩击声频率呈正相关。
{"title":"Correlation Between Implant Stability Quotient and Percussion Sound Frequency","authors":"Wansiri Peeraprasompong,&nbsp;Weerapan Aunmeungtong,&nbsp;Pathawee Khongkhunthian","doi":"10.1002/cre2.917","DOIUrl":"10.1002/cre2.917","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To determine the correlation between the primary implant stability quotient and the implant percussion sound frequency.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A total of 14 pigs' ribs were scanned using a dental cone beam computed tomography (CBCT) scanner to classify the bone specimens into three distinct bone density Hounsfield units (HU) value categories: D1 bone: &gt;1250 HU; D2: 850–1250 HU; D3: &lt;850 HU. Then, 96 implants were inserted: 32 implants in D1 bone, 32 implants in D2 bone, and 32 implants in D3 bone. The primary implant stability quotient (ISQ) was analyzed, and percussion sound was recorded using a wireless microphone connected and analyzed with frequency analysis software.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Statistically significant positive correlations were found between the primary ISQ and the bone density HU value (<i>r</i> = 0.719; <i>p</i> &lt; 0.001), and statistically significant positive correlations between the primary ISQ and the percussion sound frequency (<i>r</i> = 0.606; <i>p</i> &lt; 0.001). Furthermore, significant differences in primary ISQ values and percussion sound frequency were found between D1 and D2 bone, as well as between D1 and D3 bone. However, no significant differences were found in primary ISQ values and percussion sound frequency between D2 and D3 bone.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The primary ISQ value and the percussion sound frequency are positively correlated.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11228351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Xenogeneic Collagen Matrix Versus Free Gingival Graft for Augmenting Peri-Implant Keratinized Mucosa Around Dental Implants: A Systematic Review and Meta-Analysis 异种胶原基质与游离牙龈移植用于牙种植体周围角质化粘膜的增量:系统回顾与元分析》。
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-07 DOI: 10.1002/cre2.932
Momen A. Atieh, Maanas Shah, Abeer Hakam, Suhailah Alshaali, Reem Kasouha, Andrew Tawse-Smith, Nabeel H. M. Alsabeeha

Objectives

There is a growing evidence to suggest augmenting peri-implant keratinized mucosa in the presence of ≤ 2 mm of keratinized mucosa. However, the most appropriate surgical technique and augmentation materials have yet to be defined. The aim of this systematic review and meta-analyses was to evaluate the clinical and patient-reported outcomes of augmenting keratinized mucosa around implants using free gingival graft (FGG) versus xenogeneic collagen matrix (XCM) before commencing prosthetic implant treatment.

Material and Methods

Electronic databases were searched to identify observational studies comparing implant sites augmented with FGG to those augmented with XCM. The risk of bias was assessed using the Cochrane Collaboration's Risk of Bias tool.

Results

Six studies with 174 participants were included in the present review. Of these, 87 participants had FGG, whereas the remaining participants had XCM. At 6 months, sites augmented with FGG were associated with less changes in the gained width of peri-implant keratinized mucosa compared to those augmented with XCM (mean difference 1.06; 95% confidence interval −0.01 to 2.13; p = 0.05). The difference, however, was marginally significant. The difference between the two groups in changes in thickness of peri-implant keratinized mucosa at 6 months was statistically significantly in favor of FGG. On the other hand, XCM had significantly shorter surgical time, lower postoperative pain score, and higher color match compared to FGG.

Conclusions

Within the limitation of this review, the augmentation of keratinized mucosa using FGG before the placement of the final prosthesis may have short-term positive effects on soft tissue thickness. XCM might be considered in aesthetically demanding implant sites and where patient comfort or shorter surgical time is a priority. The evidence support, however, is of low to moderate certainty; therefore, further studies are needed to support the findings of the present review.

目的:越来越多的证据表明,如果种植体周围的角化粘膜少于 2 毫米,则建议增量种植体周围的角化粘膜。然而,最合适的手术技术和增量材料仍有待确定。本系统综述和荟萃分析的目的是评估在开始修复种植体治疗前使用游离龈移植(FGG)与异种胶原基质(XCM)增量种植体周围角化粘膜的临床和患者报告结果:对电子数据库进行检索,以确定对使用 FGG 增量的种植部位与使用 XCM 增量的种植部位进行比较的观察性研究。使用 Cochrane 协作组织的偏倚风险工具对偏倚风险进行了评估:本综述纳入了六项研究,共有 174 名参与者。其中,87 名参与者接受了 FGG 治疗,其余参与者接受了 XCM 治疗。6 个月后,与使用 XCM 增量的部位相比,使用 FGG 增量的部位种植体周围角化粘膜增宽的变化较小(平均差异为 1.06;95% 置信区间为-0.01 至 2.13;P = 0.05)。不过,差异略微显著。在 6 个月时,两组种植体周围角化粘膜厚度变化的差异在统计学上明显有利于 FGG。另一方面,与 FGG 相比,XCM 的手术时间明显更短,术后疼痛评分更低,颜色匹配度更高:在这篇综述的局限性范围内,在植入最终假体前使用 FGG 增加角化粘膜可能会对软组织厚度产生短期的积极影响。在对美观要求较高的种植部位,以及患者舒适度或手术时间较短的情况下,可以考虑使用 XCM。不过,证据支持的确定性为中低,因此需要进一步的研究来支持本综述的结论。
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引用次数: 0
Oral Hygiene With Neutral Electrolyzed Water and Systemic Therapy Increases Gastric Helicobacter pylori Eradication and Reduces Recurrence 用中性电解水进行口腔卫生和系统治疗可提高胃幽门螺旋杆菌的根除率并减少复发。
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-07 DOI: 10.1002/cre2.927
Victor Hugo Urrutia-Baca, Brenda Astrid Paz-Michel, Alma Nidia Calderon-Porras, Jany Ariadne Jiménez-Del Valle, Wendy Jazmin Alvarez-Fernández, Nicolas Mervitch-Sigal, Mario Alfredo Rodríguez-León, Myriam Angelica De La Garza-Ramos

Objectives

Helicobacter pylori gastric infection strongly correlates with gastric diseases such as chronic gastritis, functional dyspepsia, and complications such as peptic ulcers and gastric cancer. In developing countries, systemic therapies are not usually successful due to elevated antibiotic resistance. Additionally, oral H. pylori infection and periodontal disease correlate with gastric treatment failures. This study aimed to explore the effect of an integral therapy, comprising oral hygiene and concomitant systemic treatment, to increase the eradication of gastric infection and recurrences.

Materials and Methods

A prospective, randomized, four-arm, parallel-group, open-label clinical trial was conducted to investigate the efficacy of integral therapy to eradicate gastric H. pylori infection and avoid recurrences in double-positive (real-time PCR oral and gastric infection) patients. Oral hygiene involved mouthwash with neutral electrolyzed water (NEW), with or without periodontal treatment. One hundred patients were equally distributed into four groups: NS, NS-PT, NEW, and NEW-PT. All patients had concomitant systemic therapy and additionally, the following oral treatments: mouthwash with normal saline (NS), periodontal treatment and mouthwash with normal saline (NS-PT), mouthwash with NEW (NEW), and periodontal treatment and mouthwash with NEW (NEW-PT). Gastric and oral infection and symptoms were evaluated one and four months after treatments.

Results

Integral therapy with NEW-PT increased gastric eradication rates compared with NS or NS-PT (84%−96% vs. 20%−56%; p < 0.001). Even more, a protective effect of 81.2% (RR = 0.1877; 95% CI: 0.0658−0.5355; p = 0.0018) against recurrences and 76.6% (RR = 0.2439; 95% CI: 0.1380−0.4310; p < 0.001) against treatment failure (eradication of infection and associated symptoms) was observed in patients from the NEW and NEW-PT groups.

Conclusions

Implementation of oral hygiene and systemic treatment can increase the eradication of gastric infection, associated symptoms, and recurrences. NEW is recommended as an antiseptic mouthwash due to its efficacy and short- and long-term safety.

目的:幽门螺杆菌胃感染与慢性胃炎、功能性消化不良等胃病以及消化性溃疡和胃癌等并发症密切相关。在发展中国家,由于抗生素耐药性的增加,系统治疗通常并不成功。此外,口腔幽门螺杆菌感染和牙周病也与胃病治疗失败有关。本研究旨在探讨综合疗法(包括口腔卫生和同时进行的系统治疗)对提高根除胃部感染和复发率的效果:进行了一项前瞻性、随机、四臂、平行组、开放标签临床试验,研究综合疗法对根除胃幽门螺杆菌感染和避免双阳性(实时 PCR 口腔和胃感染)患者复发的疗效。口腔卫生包括使用中性电解水(NEW)漱口,同时进行或不进行牙周治疗。100 名患者平均分为四组:NS组、NS-PT组、NEW组和NEW-PT组。所有患者在接受全身治疗的同时,还接受了以下口腔治疗:用生理盐水漱口(NS)、牙周治疗和用生理盐水漱口(NS-PT)、用中性电解水漱口(NEW)和牙周治疗和用中性电解水漱口(NEW-PT)。治疗后一个月和四个月对胃部和口腔感染及症状进行评估:结果:与 NS 或 NS-PT 相比,NEW-PT 综合疗法提高了胃部根除率(84%-96% vs. 20%-56%; p 结论:口腔卫生和全身治疗的实施可提高胃部根除率(84%-96% vs. 20%-56%; p):实施口腔卫生和全身治疗可提高胃感染、相关症状和复发的根除率。由于其疗效以及短期和长期的安全性,推荐使用 NEW 作为消毒漱口水。
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引用次数: 0
Exploring the usability of simulated patient methodology in dental clinics in Western Australia: A pilot survey 探索西澳大利亚牙科诊所模拟患者方法的可用性:试点调查。
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-05 DOI: 10.1002/cre2.906
Viduni Liyange, Xin Rong Low, Joon Soo Park, Hien C. Ngo, Rhonda Clifford, Liza Seubert

Objectives

This study aimed to explore the dental staff knowledge of simulated patient methodology and support for its use to investigate dental staffs' triaging ability.

Material and Methods

Staff at dental practices in Western Australia were invited to participate in a cross-sectional online questionnaire, consisting of demographic questions, questions on triaging, and knowledge of simulated patient methodology. Descriptive and parametric tests were undertaken for quantitative data; qualitative responses were thematically analyzed.

Results

Of the 100 participants, most were female (71%), aged 25−39 years (57%), dentists (46%), and worked in private practices (60%). While 82% of participants triaged dental appointment enquiries, only 26% had heard of simulated patient studies. The majority (66%) of participants spent 1−5 min when triaging appointments and less than half (29%) asked about medical history, aggravating or alleviating factors. Although there was a general positive attitude toward use of simulated patient methodology to investigate practice, some concerns were identified.

Conclusions

The findings of our exploratory study suggests that there may be a potential for utilizing simulated patient studies to improve the care of patients by dental receptionists in general dental practices.

研究目的本研究旨在探讨牙科工作人员对模拟病人方法的了解以及对使用该方法的支持,从而调查牙科工作人员的分诊能力:邀请西澳大利亚州牙科诊所的工作人员参与横向在线问卷调查,问卷包括人口统计学问题、分诊问题和模拟患者方法知识。对定量数据进行了描述性检验和参数检验;对定性回答进行了主题分析:在 100 名参与者中,大多数为女性(71%),年龄在 25-39 岁之间(57%),牙科医生(46%),在私人诊所工作(60%)。82%的参与者负责分流牙科预约咨询,但只有26%的人听说过模拟患者研究。大多数参与者(66%)在分流预约时花了 1-5 分钟,只有不到一半的参与者(29%)询问了病史、加重或减轻病情的因素。尽管参与者普遍对使用模拟病人方法调查实践持积极态度,但也发现了一些问题:我们的探索性研究结果表明,利用模拟患者研究来改善普通牙科诊所牙科接待员对患者的护理是有潜力的。
{"title":"Exploring the usability of simulated patient methodology in dental clinics in Western Australia: A pilot survey","authors":"Viduni Liyange,&nbsp;Xin Rong Low,&nbsp;Joon Soo Park,&nbsp;Hien C. Ngo,&nbsp;Rhonda Clifford,&nbsp;Liza Seubert","doi":"10.1002/cre2.906","DOIUrl":"10.1002/cre2.906","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to explore the dental staff knowledge of simulated patient methodology and support for its use to investigate dental staffs' triaging ability.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Staff at dental practices in Western Australia were invited to participate in a cross-sectional online questionnaire, consisting of demographic questions, questions on triaging, and knowledge of simulated patient methodology. Descriptive and parametric tests were undertaken for quantitative data; qualitative responses were thematically analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 100 participants, most were female (71%), aged 25−39 years (57%), dentists (46%), and worked in private practices (60%). While 82% of participants triaged dental appointment enquiries, only 26% had heard of simulated patient studies. The majority (66%) of participants spent 1−5 min when triaging appointments and less than half (29%) asked about medical history, aggravating or alleviating factors. Although there was a general positive attitude toward use of simulated patient methodology to investigate practice, some concerns were identified.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The findings of our exploratory study suggests that there may be a potential for utilizing simulated patient studies to improve the care of patients by dental receptionists in general dental practices.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11226537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141544592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Coffee Thermocycling on Color Stability and Translucency of CAD-CAM Polychromatic High Translucent Zirconia Compared With Lithium Disilicate Glass Ceramic 与二硅酸锂玻璃陶瓷相比,咖啡热循环对 CAD-CAM 多色高透光氧化锆颜色稳定性和透光性的影响
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-05 DOI: 10.1002/cre2.918
Ratchaphat Khomprang, Jeerapa Sripetchdanond, Wareeratn Chengprapakorn

Aims and Objectives

To evaluate the effect of coffee thermocycling on color stability and translucency of CAD-CAM polychromatic high translucent zirconia compared with lithium disilicate glass ceramic.

Methods

Sixteen rectangular plates (14 × 16 × 1.0 mm) of two ceramic materials (IPS E.max CAD (IEC), IPS E.max ZirCAD Prime [IZP]) were prepared. Each specimen was measured for color coordinates using a spectrophotometer following 30,000 cycles of coffee thermocycling. CIELAB formula was used to determine color and translucency differences (ΔE and ΔTP). The means of ΔE and ΔTP were compared using independent samples t-test and were evaluated using their respective 50%:50% perceptibility and acceptability thresholds (PT and AT). One-way analysis of variance was performed to evaluate the translucency parameter (TP) and surface roughness (Ra) of each material.

Results

Mean ΔE values of IEC (4.69) and IZP (4.64) were higher than the AT (ΔE ≤ 2.7) with no significant difference found between the two groups (p = 0.202). Considering the TP, only IEC showed a statistically significant increase in TP value (p < 0.001). However, the mean ΔTP of IEC (3.25) remained within the range of acceptability (1.3 < ΔTP ≤ 4.4).

Conclusions

Within the limitations of this current study, the color stability of all materials was clinically affected by coffee thermocycling. In terms of translucency, only lithium disilicate glass ceramic was influenced by coffee thermocycling. High translucent zirconia had superior translucency stability compared to lithium disilicate glass ceramic.

目的和目标:与二硅酸锂玻璃陶瓷相比,评估咖啡热循环对 CAD-CAM 多色高透光氧化锆颜色稳定性和透光性的影响:制备了两种陶瓷材料(IPS E.max CAD (IEC)、IPS E.max ZirCAD Prime [IZP])的 16 块矩形板(14 × 16 × 1.0 毫米)。使用分光光度计对每个试样进行 30,000 次咖啡热循环后的色坐标测量。使用 CIELAB 公式确定颜色和半透明度差异(ΔE 和 ΔTP)。ΔE和ΔTP的平均值通过独立样本t检验进行比较,并使用各自的50%:50%可感知性和可接受性阈值(PT和AT)进行评估。对每种材料的半透明参数(TP)和表面粗糙度(Ra)进行了单因素方差分析:IEC(4.69)和 IZP(4.64)的平均 ΔE 值高于 AT(ΔE ≤ 2.7),两组之间无显著差异(p = 0.202)。在 TP 值方面,只有 IEC 的 TP 值出现了统计学意义上的显著增加(p 结论:IEC 的 TP 值高于 AT(ΔE ≤ 2.7),两组之间没有发现显著差异(p = 0.202):在本次研究的局限性范围内,所有材料的颜色稳定性在临床上都受到了咖啡热循环的影响。就透光度而言,只有二硅酸锂玻璃陶瓷受到咖啡热循环的影响。与二硅酸锂玻璃陶瓷相比,高半透明氧化锆的半透明稳定性更好。
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引用次数: 0
Oral Mucosa and Saliva Alterations Related to Vape 与 Vape 有关的口腔黏膜和唾液变化。
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-05 DOI: 10.1002/cre2.926
Bruna Fernandes do Carmo Carvalho, Natália de Carvalho Faria, Letícia Foiani, Gabrielle Luana Jimenez Teodoro Nepomuceno, Desirée Rosa Cavalcanti, Mônica Ghislaine Oliveira Alves, Herculano da Silva Martinho, Mário Pérez-Sayáns, Janete Dias Almeida

Objectives

Electronic nicotine delivery systems (e-cigarette, pod, and vape) are currently among the tobacco consumption of adolescents and young adults. The aim is to show oral mucosa and saliva alterations related to vape.

Material and Methods

A vape-user patient, presenting a white plaque in the posterior region of the hard palate, underwent clinical examination, sialometry, pH evaluation, and excisional biopsy of the white lesion. Molecular changes in saliva and vape liquid were analyzed by vibrational spectroscopy.

Results

The histopathological analyses showed hyperparakeratosis without dysplasia. Formaldehyde, ketones, and aromatic hydrocarbon species were identified in e-cig liquid by the FTIR.

Conclusions

The use of vape may be related to the development of hyperkeratotic lesions in the oral mucosa as well as significantly modify the patient's salivary patterns as the vape liquid presents carcinogenic and cytotoxic components in its composition.

目的:电子尼古丁递送系统(电子烟、pod 和 vape)目前是青少年和年轻人的烟草消费之一。材料和方法:对一名在硬腭后部出现白色斑块的吸食者进行了临床检查、唾液测定、pH 值评估和白色病变切除活检。通过振动光谱分析了唾液和吸食液中的分子变化:结果:组织病理学分析表明牙周角化过度,但无发育不良。傅立叶变换红外光谱分析确定了电子烟液体中的甲醛、酮和芳香烃:使用电子烟可能与口腔黏膜角化过度病变的发生有关,并且由于电子烟液的成分中含有致癌和细胞毒性成分,会显著改变患者的唾液模式。
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引用次数: 0
期刊
Clinical and Experimental Dental Research
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