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Effectiveness of Ultrasound Therapy, TheraBite Device, Masticatory Muscle Exercises, and Stabilization Splint for the Treatment of Masticatory Myofascial Pain: A Randomized Controlled Trial 超声波疗法、TheraBite 设备、咀嚼肌锻炼和稳定夹板治疗咀嚼肌筋膜疼痛的效果:随机对照试验。
IF 1.7 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-24 DOI: 10.1002/cre2.921
Kenaz Salloum, Mawia Karkoutly, Ibrahim Haddad, Jihad Abou Nassar

Background

Myofascial pain syndrome (MPS) is a particular type of temporomandibular joint disorder. Research findings comparing various treatment approaches are scarce and controversial. Therefore, this study aimed to compare the effectiveness of ultrasound therapy, stabilization splint, TheraBite device, and masticatory muscle exercises in reducing pain intensity and improving mandibular mobility in patients with MPS.

Methods

It was a single-blind, randomized, parallel-group, active-controlled trial that took place between April 2023 and October 2023 at the Department of Fixed Prosthodontics, Damascus University. Patients older than 18 years old with myofascial pain accompanied by limited jaw opening and pain lasting for at least 6 months were included. Eighty patients were randomly assigned into four groups using online randomization software: ultrasound therapy, stabilization splint, TheraBite device, and masticatory muscle exercises. Only outcome assessors were masked to treatment allocation. The exercise regimen was the exercise program for patients with TMD. The following primary outcome measures were considered at the baseline (t0), at the first (t1), second (t2), and fourth (t3) week of treatment, and at the second (t4) and fifth (t5) month of follow-up: pain intensity using the visual analogue scale, maximum interincisal opening, right lateral movement, and left lateral movement measured in millimeters.

Results

The pain level changed from severe to mild at t3 in ultrasound therapy, stabilization splint, and TheraBite device groups. In the masticatory muscle exercises group, it changed to moderate, with a significant difference between ultrasound therapy (p = 0.012) and stabilization splint (p = 0.013) groups. In addition, the mandibular mobility continued to improve at the subsequent follow-up periods (t4 and t5).

Conclusions

All therapies are equally effective after 5-month follow-up. However, ultrasound therapy and stabilization splints have the benefit of achieving rapid improvement.

Trial Registration

ISRCTN20833186.

背景:肌筋膜疼痛综合征(MPS)是颞下颌关节紊乱的一种特殊类型。对各种治疗方法进行比较的研究结果很少,而且存在争议。因此,本研究旨在比较超声波疗法、稳定夹板、TheraBite装置和咀嚼肌锻炼在减轻MPS患者疼痛强度和改善下颌活动度方面的效果:这是一项单盲、随机、平行组、主动对照试验,于 2023 年 4 月至 2023 年 10 月在大马士革大学固定义齿修复科进行。患者年龄在 18 岁以上,患有肌筋膜疼痛并伴有下颌张开受限,疼痛持续至少 6 个月。使用在线随机软件将 80 名患者随机分配到四组:超声波疗法组、稳定夹板组、TheraBite 装置组和咀嚼肌锻炼组。只有结果评估者对治疗分配进行了屏蔽。锻炼方案是针对 TMD 患者的锻炼计划。在基线(t0)、治疗第一周(t1)、第二周(t2)和第四周(t3)以及随访的第二个月(t4)和第五个月(t5)时,对以下主要结果进行了评估:使用视觉模拟量表测量的疼痛强度、最大incisal开口、右侧移动和左侧移动(以毫米为单位):结果:超声波治疗组、稳定夹板组和 TheraBite 装置组的疼痛程度在第 3 个月时由严重变为轻微。在咀嚼肌锻炼组,疼痛程度变为中度,超声波治疗组(p = 0.012)和稳定夹板组(p = 0.013)之间差异显著。此外,下颌骨活动度在随后的随访期间(t4 和 t5)继续得到改善:结论:5 个月随访后,所有疗法都同样有效。结论:所有疗法在5个月的随访后都同样有效,但超声波疗法和稳定夹板具有快速改善的优点:试验注册:ISRCTN20833186。
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引用次数: 0
Evaluating global research trends in special needs dentistry: A systematic bibliometrix analysis 评估特殊需求牙科的全球研究趋势:一项系统的文献计量学分析。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.896
Nigashiny Senthilvadevel, Jimmy Ky, Matthew Ng, Tong Zhao, Massimo Aria, Luca D'Aniello, Mathew A. W. Lim, Federica Canfora, Giulio Fortuna, Michael McCullough, Tami Yap, Rita Paolini, Antonio Celentano

Objectives

Special needs dentistry (SND) is a vast and fragmented field of study. This comprehensive bibliometric analysis aimed to evaluate the scope of SND, including the existing knowledge base, distribution structure, quantitative relationships, and research trends.

Material and Methods

A systematic search was conducted on March 10, 2022, using the Web of Science Core Collection database, covering the period from 1985 to 2021, focusing on studies reporting on special needs populations in a dentally relevant context. Records were title-screened and analyzed for key bibliometric indicators.

Results

Among 48,374 articles, 13,869 underwent bibliometric analysis. Peak SND research occurred during 1985–1997. United States led in productivity, trailed by Brazil and Japan. University of Sao Paulo excelled in Brazil, University of Washington and University of North Carolina in the United States. The Journal of Dental Research was the most productive source of research and also had the highest number of citations, followed by Community Dentistry and Oral Epidemiology. Keyword analysis revealed that “elderly”, “caries”, and “epidemiology” were the most commonly used author keywords.

Conclusions

This study represents the first bibliometric analysis of SND literature. It emphasizes the need for increased collaboration between institutions and authors. Furthermore, it suggests focusing on research input from non-dental disciplines and populations with rarer intellectual or developmental conditions.

目标:特需牙科(SND)是一个庞大而分散的研究领域。这项综合性文献计量分析旨在评估特需牙科的范围,包括现有的知识基础、分布结构、数量关系和研究趋势:2022 年 3 月 10 日,我们使用 Web of Science Core Collection 数据库对 1985 年至 2021 年期间的文献进行了系统检索,重点检索了在牙科相关背景下报告特殊需求人群的研究。对记录进行了标题筛选,并对关键文献计量指标进行了分析:在 48,374 篇文章中,有 13,869 篇进行了文献计量分析。1985-1997 年是 SND 研究的高峰期。美国的生产力居首位,巴西和日本紧随其后。巴西的圣保罗大学、美国的华盛顿大学和北卡罗来纳大学表现突出。牙科研究杂志》是研究成果最多的来源,也是被引用次数最多的来源,其次是《社区牙科》和《口腔流行病学》。关键词分析显示,"老年人"、"龋齿 "和 "流行病学 "是作者最常用的关键词:本研究首次对 SND 文献进行了文献计量分析。结论:本研究是首次对 SND 文献进行文献计量分析,强调了加强机构与作者之间合作的必要性。此外,它还建议关注非牙科学科和智力或发育状况较差人群的研究投入。
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引用次数: 0
Evaluating the patient sociodemographic factors affecting dental students' clinical communication skills using a three-perspective approach 用三视角方法评估影响牙科学生临床沟通技能的患者社会人口因素。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.897
Siti Mariam Ab Ghani, Puteri Nurul Adila Mohd Khairuddin, Budi Aslinie Md Sabri, Dieter Schonwetter, Tong Wah Lim

Objective

This study aimed to assess undergraduate dental students' communication skills in relation to patient sociodemographic factors using a three-perspective approach; the student, the patient, and the clinical instructor perspective.

Materials and Methods

A cross-sectional study was conducted using validated modified-communication tools; Patient Communication Assessment Instruments (PCAI), Student Communication Assessment Instruments (SCAI), and Clinical Communication Assessment Instruments (CCAI). Moreover, 176 undergraduate clinical year students were recruited in this study whereby each student was assessed by a clinical instructor, a patient, and self-evaluation.

Results

The clinical communication skills domains were not significantly influenced by patient sociodemographic factors, including sex, educational background, and the number of visits (p > .05). However, this study revealed a statistically significant difference in the domain of “caring and respectful” of the SCAI between the low- and middle-income groups.

Conclusions

Overall, most of the patient sociodemographic factors did not affect clinical communication skills. However, patient income groups played a significant role in one of the communication domains.

目的:本研究旨在采用三视角方法(学生视角、患者视角和临床指导教师视角)评估牙科本科生的沟通技巧与患者社会人口学因素的关系:本研究旨在采用三视角方法(学生视角、患者视角和临床教师视角)评估牙科本科生的沟通技巧与患者社会人口学因素的关系:使用经过验证的改良沟通工具:患者沟通评估工具(PCAI)、学生沟通评估工具(SCAI)和临床沟通评估工具(CCAI)进行了一项横断面研究。此外,本研究还招募了 176 名本科临床年级学生,每位学生都接受了临床教师、患者和自我评价的评估:结果:临床沟通技能领域受患者社会人口学因素(包括性别、教育背景和就诊次数)的影响不大(P > .05)。然而,本研究显示,在 SCAI 的 "关怀和尊重 "领域,低收入群体和中等收入群体之间的差异具有统计学意义:总体而言,大多数患者的社会人口学因素并不影响临床沟通技巧。结论:总体而言,大多数患者的社会人口学因素并不影响临床沟通技巧,但患者的收入群体在其中一个沟通领域中起着重要作用。
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引用次数: 0
An In Vitro Evaluation of Periotest Implant Stability Measurements Taken on Implant Retained Crowns and Healing Abutments 对种植体固位冠和愈合基台的 Periotest 种植体稳定性测量进行体外评估。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.910
Cianna O'Brien, David Naughton, Bahman Honari, Lewis Winning, Ioannis Polyzois

Objective

To assess the reliability of implant stability measurements recorded with the Periotest device and to investigate the differences in values when these measurements were taken on implant retained crowns and healing abutments.

Materials and Methods

Fifty-six implants in eight synthetic bone blocks were used to carry out implant stability measurements using the Periotest device by two different operators. Each block constituted an example of bone of density D1, D2, D3, or D4, and two blocks of each density were used. The healing abutments placed were of a height to allow approximately 6 mm of the implant-abutment complex to be supracrestal and temporary crowns were made to match the dimensions of an average central incisor. Descriptive statistics were used to describe the perio test values (PTVs) at each of the different heights on the implant abutments and implant crowns. Means for each site were calculated and distribution of data assessed using the Kruskal Wallis test. The interclass correlation coefficient (ICC) was used to determine the relationship between the PTVs recorded on the implant abutments and implant crowns.

Results

The mean PTV (±standard devidation) recorded across all sites was 5.57 ± 11.643 on the implant abutments, and 12.27 ± 11.735 on the temporary crowns. Excellent/good inter-operator ICCs were recorded for the mid-abutment site in all bone blocks D1–D4 (ICC = 0.814, p < 0.001, ICC = 0.922, p < 0.001, ICC = 0.938, p < 0.001, ICC = 776, p < 0.001). For mid crown sites, ICC between operators was excellent/good only for recordings in D2 bone (ICC = 0.897, p < 0.001).

Conclusions

Periotest device seems to be able to reliably measure implant stability across all types of bones when the implant stability is assessed at approximately 3 mm coronal to the implant platform for abutments and 4.5 mm for implant supported single crowns.

目的评估使用 Periotest 设备记录的种植体稳定性测量值的可靠性,并研究这些测量值在种植体固位冠和愈合基台上的差异:两个不同的操作者使用 Periotest 设备对八个合成骨块中的 56 个种植体进行了种植体稳定性测量。每个骨块的密度分别为 D1、D2、D3 或 D4,每个密度使用两个骨块。植入的愈合基台的高度为种植体-基台复合体约 6 毫米,临时牙冠的尺寸与普通中切牙一致。使用描述性统计来描述种植基台和种植体冠不同高度处的周缘测试值(PTV)。使用 Kruskal Wallis 检验法计算每个部位的平均值并评估数据的分布情况。类间相关系数(ICC)用于确定种植体基台和种植体冠上记录的 PTV 之间的关系:所有部位记录的平均 PTV(±标准偏差)为:种植基台 5.57 ± 11.643,临时牙冠 12.27 ± 11.735。在所有骨块 D1-D4 中的基台中间部位,记录到了极好/良好的操作者间 ICC(ICC = 0.814,p 结论:Periotest 设备似乎能够准确地测量种植体的位置:如果在基台与种植体平台之间约 3 毫米的冠状面上评估种植体的稳定性,在种植体支持的单冠上评估 4.5 毫米的冠状面上评估种植体的稳定性,那么 Periotest 设备似乎能够可靠地测量所有类型骨骼的种植体稳定性。
{"title":"An In Vitro Evaluation of Periotest Implant Stability Measurements Taken on Implant Retained Crowns and Healing Abutments","authors":"Cianna O'Brien,&nbsp;David Naughton,&nbsp;Bahman Honari,&nbsp;Lewis Winning,&nbsp;Ioannis Polyzois","doi":"10.1002/cre2.910","DOIUrl":"10.1002/cre2.910","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To assess the reliability of implant stability measurements recorded with the Periotest device and to investigate the differences in values when these measurements were taken on implant retained crowns and healing abutments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Fifty-six implants in eight synthetic bone blocks were used to carry out implant stability measurements using the Periotest device by two different operators. Each block constituted an example of bone of density D1, D2, D3, or D4, and two blocks of each density were used. The healing abutments placed were of a height to allow approximately 6 mm of the implant-abutment complex to be supracrestal and temporary crowns were made to match the dimensions of an average central incisor. Descriptive statistics were used to describe the perio test values (PTVs) at each of the different heights on the implant abutments and implant crowns. Means for each site were calculated and distribution of data assessed using the Kruskal Wallis test. The interclass correlation coefficient (ICC) was used to determine the relationship between the PTVs recorded on the implant abutments and implant crowns.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean PTV (±standard devidation) recorded across all sites was 5.57 ± 11.643 on the implant abutments, and 12.27 ± 11.735 on the temporary crowns. Excellent/good inter-operator ICCs were recorded for the mid-abutment site in all bone blocks D1–D4 (ICC = 0.814, <i>p</i> &lt; 0.001, ICC = 0.922, <i>p</i> &lt; 0.001, ICC = 0.938, <i>p</i> &lt; 0.001, ICC = 776, <i>p</i> &lt; 0.001). For mid crown sites, ICC between operators was excellent/good only for recordings in D2 bone (ICC = 0.897, <i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Periotest device seems to be able to reliably measure implant stability across all types of bones when the implant stability is assessed at approximately 3 mm coronal to the implant platform for abutments and 4.5 mm for implant supported single crowns.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11180707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral Irrigation Devices: A Scoping Review 口腔冲洗设备:范围审查。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.912
Farzana Sarkisova, Zac Morse, Kevin Lee, Nagihan Bostanci

Objectives

Self-performed oral hygiene is essential for preventing dental caries, periodontal, and peri-implant diseases. Oral irrigators are adjunctive oral home care aids that may benefit oral health. However, the effects of oral irrigation on oral health, its role in oral home care, and its mechanism of action are not fully understood. A comprehensive search of the literature revealed no existing broad scoping reviews on oral irrigators. Therefore, this study aimed to provide a comprehensive systematic review of the literature on oral irrigation devices and identify evidence gaps.

Methods

The Joanna Briggs Institute and Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews guidelines were utilized to prepare the review. Four databases and eight gray literature sources were searched for English publications across any geographical location or setting.

Results

Two hundred and seventy-five sources were included, predominantly from scientific journals and academic settings. Most studies originated from North America. Research primarily involved adults, with limited studies in children and adolescents. Oral irrigation was safe and well-accepted when used appropriately. It reduced periodontal inflammation, potentially by modulating the oral microbiota, but further research needs to clarify its mechanism of action. Promising results were reported in populations with dental implants and special needs. Patient acceptance appeared high, but standardized patient-reported outcome measures were rarely used. Anti-inflammatory benefits occurred consistently across populations and irrigant solutions. Plaque reduction findings were mixed, potentially reflecting differences in study designs and devices.

Conclusions

Oral irrigators reduce periodontal inflammation, but their impact on plaque removal remains unclear. Well-designed, sufficiently powered trials of appropriate duration need to assess the clinical, microbiological, and inflammatory responses of the periodontium to oral irrigation, particularly those with periodontitis, dental implants, and special needs. Patient-reported outcome measures, costs, caries prevention, and environmental impact of oral irrigation need to be compared to other oral hygiene aids.

目的:自我进行口腔卫生对于预防龋齿、牙周病和种植体周围疾病至关重要。口腔冲洗器是口腔家庭护理的辅助工具,可能有益于口腔健康。然而,口腔冲洗对口腔健康的影响、其在口腔家庭护理中的作用及其作用机制尚未完全清楚。在对文献进行全面检索后发现,目前还没有关于口腔冲洗器的广泛范围综述。因此,本研究旨在对有关口腔冲洗器的文献进行全面系统的综述,并找出证据差距:本综述采用了乔安娜-布里格斯研究所(Joanna Briggs Institute)和《系统综述和元分析首选报告项目》(Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews)指南。在四个数据库和八个灰色文献来源中搜索了任何地理位置或环境下的英文出版物:结果:共收录了 275 篇文献,主要来自科学期刊和学术机构。大多数研究来自北美。研究主要涉及成年人,对儿童和青少年的研究有限。如果使用得当,口腔冲洗是安全的,也是被广泛接受的。它可能通过调节口腔微生物群来减少牙周炎症,但还需要进一步的研究来明确其作用机制。据报道,在种植牙和有特殊需求的人群中取得了可喜的成果。患者的接受度似乎很高,但很少使用标准化的患者报告结果测量方法。不同人群和不同的冲洗液都能产生一致的消炎效果。减少牙菌斑的结果不一,可能反映了研究设计和设备的差异:结论:口腔冲洗器能减轻牙周炎症,但对去除牙菌斑的影响仍不明确。需要对口腔冲洗对牙周的临床、微生物和炎症反应进行评估,尤其是那些患有牙周炎、种植牙和有特殊需求的患者。需要将患者报告的结果测量、成本、龋齿预防以及口腔冲洗对环境的影响与其他口腔卫生辅助工具进行比较。
{"title":"Oral Irrigation Devices: A Scoping Review","authors":"Farzana Sarkisova,&nbsp;Zac Morse,&nbsp;Kevin Lee,&nbsp;Nagihan Bostanci","doi":"10.1002/cre2.912","DOIUrl":"10.1002/cre2.912","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Self-performed oral hygiene is essential for preventing dental caries, periodontal, and peri-implant diseases. Oral irrigators are adjunctive oral home care aids that may benefit oral health. However, the effects of oral irrigation on oral health, its role in oral home care, and its mechanism of action are not fully understood. A comprehensive search of the literature revealed no existing broad scoping reviews on oral irrigators. Therefore, this study aimed to provide a comprehensive systematic review of the literature on oral irrigation devices and identify evidence gaps.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The Joanna Briggs Institute and Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews guidelines were utilized to prepare the review. Four databases and eight gray literature sources were searched for English publications across any geographical location or setting.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Two hundred and seventy-five sources were included, predominantly from scientific journals and academic settings. Most studies originated from North America. Research primarily involved adults, with limited studies in children and adolescents. Oral irrigation was safe and well-accepted when used appropriately. It reduced periodontal inflammation, potentially by modulating the oral microbiota, but further research needs to clarify its mechanism of action. Promising results were reported in populations with dental implants and special needs. Patient acceptance appeared high, but standardized patient-reported outcome measures were rarely used. Anti-inflammatory benefits occurred consistently across populations and irrigant solutions. Plaque reduction findings were mixed, potentially reflecting differences in study designs and devices.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Oral irrigators reduce periodontal inflammation, but their impact on plaque removal remains unclear. Well-designed, sufficiently powered trials of appropriate duration need to assess the clinical, microbiological, and inflammatory responses of the periodontium to oral irrigation, particularly those with periodontitis, dental implants, and special needs. Patient-reported outcome measures, costs, caries prevention, and environmental impact of oral irrigation need to be compared to other oral hygiene aids.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11180943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The assessment of glutathione, glutathione peroxidase, glutathione reductase, and oxidized glutathione in patients with periodontitis—A systematic review and meta-analysis 牙周炎患者谷胱甘肽、谷胱甘肽过氧化物酶、谷胱甘肽还原酶和氧化谷胱甘肽的评估--系统综述和荟萃分析。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.907
Khadijah Mohideen, Chandrasekaran Krithika, T. Jeyanthikumari, N. V. Vani, Safal Dhungel, Snehashish Ghosh

Objective

The present systematic review explored the involvement of enzymatic and nonenzymatic antioxidants in periodontitis, drawing from established literature.

Materials and Methods

The research approach encompassed an extensive electronic search from 2000 to 2023 across databases such as PubMed, Science Direct, and Wiley Online Library and cross-referencing using specific keywords.

Results

The initial literature exploration generated a total of 766 articles. After thoroughly examining the abstracts, 693 articles were excluded from consideration due to duplication and lack of relevance to the central research inquiry. Following that, 73 articles were left for in-depth evaluation. Following a qualitative assessment, 35 studies that satisfied the inclusion criteria were chosen, while 38 were removed for not meeting the necessary standards. Within this selection, a meta-analysis was conducted on 11 articles that provided consistent data for quantitative synthesis. Specifically, the analysis of glutathione (GSH) levels in serum samples revealed a standardized mean difference (SMD) of −5.552 µg/mL (CI 95%: −9.078 to −2.026; P-0.002). In contrast, the analysis of glutathione peroxidase (GPx) enzymes in gingival crevicular fluid (GCF) samples displayed an overall SMD of 2.918 ng/µL (CI 95%: 0.372–5.465; P-0.025), while salivary samples exhibited an overall SMD value of 0.709 U/l (95% CI: −1.907–3.325; P-0.596) which is of insignificant.

Conclusion

The systematic review findings suggest a notable decrease in antioxidant enzymes across various systemic biological samples among patients with periodontitis, contrasting with the results from gingival tissue samples meta-analysis of GPx enzyme.

目的:本系统综述从已有文献中汲取资料,探讨了酶和非酶抗氧化剂在牙周炎中的作用:研究方法包括从 2000 年到 2023 年在 PubMed、Science Direct 和 Wiley Online Library 等数据库中进行广泛的电子检索,并使用特定关键词进行交叉引用:最初的文献探索共收集到 766 篇文章。在对摘要进行深入研究后,有 693 篇文章因重复和与中心研究调查缺乏相关性而被排除在外。之后,留下 73 篇文章进行深入评估。经过定性评估,35 篇符合纳入标准的研究被选中,38 篇因不符合必要标准而被剔除。在这一选择范围内,对 11 篇为定量综合提供了一致数据的文章进行了荟萃分析。具体来说,对血清样本中谷胱甘肽(GSH)水平的分析表明,其标准化平均差(SMD)为-5.552 µg/mL (CI 95%: -9.078 to -2.026; P-0.002)。相比之下,对牙龈缝隙液(GCF)样本中谷胱甘肽过氧化物酶(GPx)的分析显示,总体 SMD 为 2.918 ng/µL(CI 95%:0.372-5.465;P-0.025),而唾液样本显示的总体 SMD 值为 0.709 U/l (95% CI:-1.907-3.325;P-0.596),微不足道:系统综述结果表明,牙周炎患者各种系统生物样本中的抗氧化酶明显减少,这与牙龈组织样本中 GPx 酶的荟萃分析结果形成了鲜明对比。
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引用次数: 0
The effect of different implant-abutment types and heights on screw loosening in cases with increased crown height space 在牙冠高度空间增大的情况下,不同的种植体基台类型和高度对螺钉松动的影响。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.894
Amirreza Hendi, Sobhan Mirzaee, Mehran Falahchai

Objectives

The stability of the abutment screw is pivotal for successful implant-supported restorations, yet screw loosening remains a common complication, leading to compromised function and potential implant failure. This study aims to evaluate the effect of different implant-abutment types and heights on screw loosening in cases with increased crown height space (CHS).

Materials and Methods

In this in vitro study, a total of 64 abutments in eight distinct groups based on their type and height were evaluated. These groups included stock, cast, and milled abutments with heights of 4 mm (groups S4, C4, and M4), 7 mm (groups S7, C7, and M7), and 10 mm (groups C10 and M10). Removal torque loss (RTL) was assessed both before and after subjecting the abutments to dynamic cyclic loading. Additionally, the differences between initial RTL and RTL following cyclic loading were analyzed for each group (p < .05).

Results

The C10 group demonstrated the highest RTL, whereas the S4 group exhibited the lowest initial RTL percentage (p < .05). Furthermore, the study established significant variations in RTL percentages and the discrepancies between initial and postcyclic loading RTL across different abutment groups (p < .05). Additionally, both abutment types and heights were found to significantly influence the RTL percentage (p < .05).

Conclusion

The type and height of the implant abutment affected screw loosening, and in an increased CHS of 12 mm, using a stock abutment with a postheight of 4 mm can be effective in minimizing screw loosening.

目的:基台螺丝的稳定性是种植体支持修复成功的关键,但螺丝松动仍然是常见的并发症,会导致功能受损和潜在的种植体失败。本研究旨在评估在牙冠高度空间(CHS)增大的情况下,不同种植体基台类型和高度对螺丝松动的影响:在这项体外研究中,根据基台的类型和高度,共对 8 个不同组别中的 64 个基台进行了评估。这些组包括高度为 4 毫米(S4、C4 和 M4 组)、7 毫米(S7、C7 和 M7 组)和 10 毫米(C10 和 M10 组)的库存基台、铸造基台和研磨基台。在基台承受动态循环加载之前和之后,都对移除扭矩损失(RTL)进行了评估。此外,还分析了各组初始 RTL 与循环加载后 RTL 之间的差异(p 结果:C10 组的 RTL 最高,而 S4 组的初始 RTL 百分比最低(p 结论:C10 组和 S4 组的初始 RTL 百分比最高,而 S4 组的初始 RTL 百分比最低:种植体基台的类型和高度对螺钉松动有影响,在 CHS 增加到 12 mm 的情况下,使用后高度为 4 mm 的库存基台可以有效地减少螺钉松动。
{"title":"The effect of different implant-abutment types and heights on screw loosening in cases with increased crown height space","authors":"Amirreza Hendi,&nbsp;Sobhan Mirzaee,&nbsp;Mehran Falahchai","doi":"10.1002/cre2.894","DOIUrl":"10.1002/cre2.894","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The stability of the abutment screw is pivotal for successful implant-supported restorations, yet screw loosening remains a common complication, leading to compromised function and potential implant failure. This study aims to evaluate the effect of different implant-abutment types and heights on screw loosening in cases with increased crown height space (CHS).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>In this in vitro study, a total of 64 abutments in eight distinct groups based on their type and height were evaluated. These groups included stock, cast, and milled abutments with heights of 4 mm (groups S4, C4, and M4), 7 mm (groups S7, C7, and M7), and 10 mm (groups C10 and M10). Removal torque loss (RTL) was assessed both before and after subjecting the abutments to dynamic cyclic loading. Additionally, the differences between initial RTL and RTL following cyclic loading were analyzed for each group (<i>p</i> &lt; .05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The C10 group demonstrated the highest RTL, whereas the S4 group exhibited the lowest initial RTL percentage (<i>p</i> &lt; .05). Furthermore, the study established significant variations in RTL percentages and the discrepancies between initial and postcyclic loading RTL across different abutment groups (<i>p</i> &lt; .05). Additionally, both abutment types and heights were found to significantly influence the RTL percentage (<i>p</i> &lt; .05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The type and height of the implant abutment affected screw loosening, and in an increased CHS of 12 mm, using a stock abutment with a postheight of 4 mm can be effective in minimizing screw loosening.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11180708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Histopathologic Types of Gingival Lesions in the Iranian Population: A 22-Year Retrospective Study 伊朗人口牙龈病变组织病理学类型的流行率:一项为期 22 年的回顾性研究
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.911
Nafiseh Shamloo, Mostafa Alam, Armin Khaleghi

Objectives

Gingiva is one of the supporting tissues around the teeth that can be affected by various neoplastic or nonneoplastic lesions. Previous studies have examined several types of gingival lesions, but the lack of a standardized classification system has hindered meaningful comparisons. Additionally, many studies focused primarily on reactive lesions. Our study aims to contribute to the understanding of gingival lesions by investigating their prevalence across age groups, genders, sites, and by their clinical presentation. This research could lead to improved diagnostic accuracy and treatment strategies.

Materials and Methods

This retrospective study explores the prevalence of gingival lesions based on biopsies during a 22-year span. The patient's demographic details, including age, gender, and lesion's clinical presentation were systematically collected. These lesions were categorized into six groups. Descriptive statistics, χ2 test of independence, and one-way ANOVA were used for data analysis.

Results

Among the 7668 biopsied lesions, 684 (8.9%) lesions were located in the gingiva, with a greater occurrence in women (63.5%). Soft tissue tumors represented the most prevalent group in the gingival lesions (72.1%), and peripheral giant cell granuloma (PGCG) was the most frequent lesion (21.2%), followed by, pyogenic granuloma (19.3%), peripheral ossifying fibroma (17.8%) and focal fibrous hyperplasia (7.6%); all of which predominantly affected women, with mean ages falling in the fourth decade of life. Squamous cell carcinoma was recognized as the most common malignancy.

Conclusion

In this study, PGCG was found to be the most common lesion in the gingiva in Iranian population. Further analysis using a unanimous categorization is required to confirm these results.

目的:牙龈是牙齿周围的支持组织之一,可能受到各种肿瘤性或非肿瘤性病变的影响。以往的研究已对几种类型的牙龈病变进行了研究,但由于缺乏标准化的分类系统,因此无法进行有意义的比较。此外,许多研究主要关注反应性病变。我们的研究旨在通过调查不同年龄组、不同性别、不同部位以及不同临床表现的牙龈病变发生率,加深对牙龈病变的了解。这项研究可提高诊断准确性并改进治疗策略:这项回顾性研究根据 22 年间的活组织切片探讨了牙龈病变的患病率。研究系统地收集了患者的人口统计学资料,包括年龄、性别和病变的临床表现。这些病变被分为六组。数据分析采用了描述性统计、χ2独立性检验和单因素方差分析:结果:在 7668 例活检病变中,有 684 例(8.9%)位于牙龈,其中女性病例较多(63.5%)。软组织肿瘤是牙龈病变中最常见的一类(72.1%),外周巨细胞肉芽肿(PGCG)是最常见的病变(21.2%),其次是化脓性肉芽肿(19.3%)、外周骨化性纤维瘤(17.8%)和局灶性纤维增生症(7.6%);所有这些病变都以女性为主,平均年龄在 40 岁左右。鳞状细胞癌是最常见的恶性肿瘤:本研究发现,PGCG 是伊朗人群中最常见的牙龈病变。需要使用一致的分类方法进行进一步分析,以确认这些结果。
{"title":"Prevalence of Histopathologic Types of Gingival Lesions in the Iranian Population: A 22-Year Retrospective Study","authors":"Nafiseh Shamloo,&nbsp;Mostafa Alam,&nbsp;Armin Khaleghi","doi":"10.1002/cre2.911","DOIUrl":"10.1002/cre2.911","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Gingiva is one of the supporting tissues around the teeth that can be affected by various neoplastic or nonneoplastic lesions. Previous studies have examined several types of gingival lesions, but the lack of a standardized classification system has hindered meaningful comparisons. Additionally, many studies focused primarily on reactive lesions. Our study aims to contribute to the understanding of gingival lesions by investigating their prevalence across age groups, genders, sites, and by their clinical presentation. This research could lead to improved diagnostic accuracy and treatment strategies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>This retrospective study explores the prevalence of gingival lesions based on biopsies during a 22-year span. The patient's demographic details, including age, gender, and lesion's clinical presentation were systematically collected. These lesions were categorized into six groups. Descriptive statistics, <i>χ</i><sup>2</sup> test of independence, and one-way ANOVA were used for data analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among the 7668 biopsied lesions, 684 (8.9%) lesions were located in the gingiva, with a greater occurrence in women (63.5%). Soft tissue tumors represented the most prevalent group in the gingival lesions (72.1%), and peripheral giant cell granuloma (PGCG) was the most frequent lesion (21.2%), followed by, pyogenic granuloma (19.3%), peripheral ossifying fibroma (17.8%) and focal fibrous hyperplasia (7.6%); all of which predominantly affected women, with mean ages falling in the fourth decade of life. Squamous cell carcinoma was recognized as the most common malignancy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In this study, PGCG was found to be the most common lesion in the gingiva in Iranian population. Further analysis using a unanimous categorization is required to confirm these results.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11180844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the effect of depression on clinical symptoms of temporomandibular disorder in young stressful men 研究抑郁症对年轻压力男性颞下颌关节紊乱临床症状的影响。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-16 DOI: 10.1002/cre2.909
Maryam Sadrzadeh Afshar, Behzad Salari, Sina Varasteh Nejad

Objectives

The objective of this study was to investigate the relationship of the depression level with temporomandibular disorders (TMDs) in young conscripts as a population with chronic stresses.

Material and Methods

A total number of 144 male conscripts with chronic stress and different levels of depression were assigned to four groups according to the Beck's Depression Inventory (BDI). The control group consisted of age-matched male conscripts without chronic stress. The diagnosis of TMD was made according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Data were analyzed using Mann–Whitney and chi-square tests.

Results

The participants with severe depression were significantly more susceptible to have TMD (p = .001) followed by the moderate depression, borderline clinical depression, mild mood disturbance, and control groups. The TMD diagnoses were more prevalent within depression groups compared with the control population (p = .01).

Conclusions

The level of depression is directly associated with the presence of TMD in young men with chronic stress.

研究目的本研究的目的是调查作为长期压力人群的应征青年的抑郁程度与颞下颌关节紊乱症(TMDs)之间的关系:根据贝克抑郁量表(BDI)将患有慢性压力和不同抑郁程度的 144 名男性应征者分为四组。对照组由年龄匹配、无慢性压力的男性应征者组成。TMD 的诊断依据是颞下颌关节紊乱诊断标准(DC/TMD)。数据采用曼-惠特尼检验和卡方检验进行分析:结果:重度抑郁症患者更易患 TMD(p = .001),其次是中度抑郁症组、边缘临床抑郁症组、轻度情绪障碍组和对照组。与对照组相比,抑郁组的 TMD 诊断率更高(p = .01):结论:抑郁程度与患有慢性压力的年轻男性是否患有 TMD 直接相关。
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引用次数: 0
Diagnostic value of aMMP-8 and azurocidin in peri-implant sulcular fluid as biomarkers of peri-implant health or disease 作为种植体周围健康或疾病的生物标志物,种植体周围龈沟液中的 aMMP-8 和 azurocidin 具有诊断价值。
IF 1.8 Q3 Dentistry Pub Date : 2024-06-09 DOI: 10.1002/cre2.883
Vithleem Xanthopoulou, Ismo T. Räisänen, Timo Sorsa, Dimitrios Tortopidis, Dimitra Sakellari

Objective

The objective of this study was to investigate the effectiveness of testing for active matrix metalloproteinase-8 (aMMP-8) by a quantitative point-of-care (PoC), chairside lateral flow immunotest and azurocidin, in the peri-implant sulcular fluid (PISF), as biomarkers for the presence or absence of peri-implant diseases.

Background

Current research indicates that proinflammatory cytokines and extracellular matrix-degrading enzymes may be of value to diagnose and predict peri-implant disease initiation and progression, but more data are needed.

Methods

Eighty patients with implants were recruited. PISF samples were collected and quantitatively analyzed for aMMP-8 (chairside) and azurocidin with ELISA. Radiographic assessments and clinical indices (probing depth, probing attachment level, bleeding on probing, and plaque) were recorded after sampling. Kruskal-Wallis test and pairwise post hoc Dunn-Bonferroni test were used to relate aMMP-8 levels and azurocidin levels to clinical parameters. The diagnostic ability of aMMP-8 (ng/mL) and azurocidin was analyzed by receiver operator curve analysis. Area under the curve (AUC) was calculated and the Spearman's rho, and the coefficient of determination (R2) were used to calculate the correlations between aMMP-8, azurocidin, and periodontal parameters.

Results

Statistically significant differences were observed for aMMP-8 levels but not for azurocidin between healthy implants, implants with mucositis, and those with peri-implantitis (13.65 ± 7.18, 32.33 ± 21.20, and 73.07 ± 43.93 ng/mL, respectively), (Kruskall–Wallis test p < .05). The aMMP-8 test with a threshold of 20 ng/mL has a sensitivity of 71.7% and a specificity of 77.8% to identify peri-implantitis and healthy implants, respectively. AUC was found to be 0.814, and the accuracy of the method reaches 73.8%. Above a cutoff value of 33.7 ng/mL of aMMP-8, the accuracy of the test to detect peri-implantitis reaches 77.5% in relation to 62.5% of BoP from the same site.

Conclusion

Taken collectively, present data indicate that the aMMP-8 PoC lateral flow immunotest can be a beneficial, adjunctive diagnostic quantitative tool for real-time screening for peri-implant diseases.

研究目的本研究的目的是探讨通过定量床旁侧流免疫测定(PoC)检测种植体周围龈沟液(PISF)中的活性基质金属蛋白酶-8(aMMP-8)和氮芥作为生物标志物检测种植体周围疾病存在与否的有效性:背景:目前的研究表明,促炎细胞因子和细胞外基质降解酶可能对诊断和预测种植体周围疾病的发生和发展有价值,但还需要更多的数据:方法:招募了 80 名种植体患者。收集 PISF 样本,并用 ELISA 对 aMMP-8(椅旁)和azurocidin 进行定量分析。取样后记录放射学评估和临床指标(探诊深度、探诊附着水平、探诊出血和牙菌斑)。采用 Kruskal-Wallis 检验和配对后 Dunn-Bonferroni 检验将 aMMP-8 和 Azurocidin 水平与临床指标联系起来。通过接收者运算曲线分析法分析了aMMP-8(纳克/毫升)和氮芥苷的诊断能力。计算了曲线下面积(AUC),并使用斯皮尔曼rho和判定系数(R2)计算了aMMP-8、氮芥和牙周参数之间的相关性:结果:在健康种植体、粘膜炎种植体和种植体周围炎种植体之间,aMMP-8 水平有统计学意义的差异(分别为 13.65 ± 7.18、32.33 ± 21.20 和 73.07 ± 43.93 ng/mL),而氮杂络氨酸水平无统计学意义的差异(Kruskall-Wallis 检验 p 结论:综上所述,本数据表明 aMMP-8 PoC 侧流免疫测定是一种有益的辅助诊断定量工具,可用于实时筛查种植体周围疾病。
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引用次数: 0
期刊
Clinical and Experimental Dental Research
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