Clinical and Experimental Dental Research最新文献

{"title":"Assessment of Deep Convolutional Neural Network Models for the Classification of Benign Fibro-Osseous Lesions of the Jaws","authors":"Paniti Achararit,&nbsp;Chawan Manaspon,&nbsp;Chavin Jongwannasiri,&nbsp;Kraisorn Sappayatosok,&nbsp;Thanaphum Osathanon,&nbsp;Ekarat Phattarataratip","doi":"10.1002/cre2.70244","DOIUrl":"https://doi.org/10.1002/cre2.70244","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Benign fibro-osseous lesions (BFOL) constitute a group of pathologic entities with marked overlapping histopathologic features but are diverse in nature and clinical behaviors. Accurate diagnoses of BFOLs necessitate clinical-pathological correlations, which are paramount for their appropriate management. Recent research indicates the potential utility of artificial intelligence in diagnostic pathology. Here, we aimed to assess the performance of the deep convolutional neural network (DCNN) models for BFOL classification and investigate its impact on the diagnostic performance of oral pathologists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Microscopic slides from 68 patients diagnosed with cemento-ossifying fibroma (COF), fibrous dysplasia (FD), and cemento-osseous dysplasia (COD) were collected. The image patches from each slide were processed, augmented, and used to train and validate the five pre-trained DCNN models for BFOL classification. The best-performing model was selected to evaluate its diagnostic performance on the testing data set, compared with experienced oral pathologists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The InceptionV3 model showed the highest and most balanced overall performance in BFOL classification. It demonstrated the highest accuracy (96.7%) in classifying COF, followed by COD (83.3%), and FD (80.0%), respectively. The model accuracy in identifying COF was greater than the average performance of pathologists (90.0%). However, pathologists performed better in classifying COD (87.2%) and FD (95.0%). With DCNN assistance, pathologists significantly improved the accuracy, sensitivity, and specificity in distinguishing BFOLs while reducing the average diagnosis time.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The DCNN model has the potential to be developed as an auxiliary tool, assisting pathologists in diagnosing BFOLs. Through ongoing refinements, artificial intelligence assistance can aid pathologists in enhancing the accuracy and efficiency of BFOL diagnosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 6","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cre2.70244","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145297282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peri-Implantitis and Survival Outcomes of Tissue Level Versus Bone Level Dental Implants: A Systematic Review and Meta-Analysis","authors":"Momen A. Atieh,&nbsp;Maanas Shah,&nbsp;Abeer Hakam,&nbsp;Ahmad Aid,&nbsp;Andrew Tawse-Smith,&nbsp;Nabeel H. M. Alsabeeha","doi":"10.1002/cre2.70242","DOIUrl":"10.1002/cre2.70242","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The aim of this systematic review and meta-analyses was to evaluate the outcomes of using tissue level in comparison to bone level implants in terms of clinical and radiographic changes, peri-implantitis, and implant failure rates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Electronic databases were searched to identify randomized studies that compared tissue level to bone level implant. The risk of bias was assessed using the Cochrane Collaboration's Risk of Bias tool. Data were analyzed using a statistical software program.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 798 studies were identified, of which, five studies with 501 dental implants in 241 participants were included. Overall meta-analysis showed that the use of tissue level implants had lower rates of peri-implantitis (relative risk [RR] 0.59; 95% confidence interval [CI] 0.14–2.48; <i>p</i> = 0.47) and implant failure (RR 0.59; 95% CI 0.07–4.69; <i>p</i> = 0.62) but the differences were not statistically significant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Tissue level and bone level have comparable survival rates and risk of peri-implantitis within 1–5 years of observation. Additionally, no significant differences in probing pocket depths and marginal bone level changes were observed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Relevance</h3>\u0000 \u0000 <p>Tissue level implants demonstrated lower rates of peri-implantitis and implant failure, as well as smaller changes in probing pocket depths at 12 and 24 months, compared to bone level implants. Although these differences were not statistically significant, they suggest potential clinical advantages of tissue level implants in maintaining peri-implant health and stability over time.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 5","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12529224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145299066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Link Between Social Capital and Edentulism in Low- and Middle-Income Countries","authors":"Saida Ben-Bihi,&nbsp;Yanfei Guo,&nbsp;Richard Olofsson,&nbsp;Hülya Çevik-Aras,&nbsp;Junmei Miao Jonasson","doi":"10.1002/cre2.70241","DOIUrl":"10.1002/cre2.70241","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Although social capital (SC) has received growing attention in public health, no research has yet compared how SC and oral health are associated in diverse contexts. This cross-sectional study aims to examine the association of community and individual-level SC with edentulism among adults aged 50 and above in five low- and middle-income countries (LMICs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Data are from SAGE-wave 1 (2007–2010), including 27,676 participants aged 50 years or older from China (<i>N</i> = 12,830), Ghana (<i>N</i> = 4261), India (<i>N</i> = 6040), Mexico (<i>N</i> = 1327), and South Africa (<i>N</i> = 3218). The primary outcome was self-reported edentulism. Cognitive and structural SC were used to measure SC at the individual and community levels. The association between SC dimensions and oral health was investigated using a two-level multilevel logistic regression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Multilevel analysis revealed that low individual and community structural SC are independently associated with edentulism in China (OR 1.43; CI 1.08–1.89 and OR 1.95; CI 1.32–2.90, respectively). In South Africa, low individual cognitive SC was negatively associated with edentulism (OR 0.48; CI 0.24–0.98), while low individual structural SC was positively associated with edentulism (OR 2.34; CI 1.16–4.74). In Ghana, only participants living in middle community structural SC had higher odds of being edentulous after adjustment for all potential confounders (OR 1.78; CI 0.71–2.96). In Mexico and India, no association was found between any dimensions of SC and oral health.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The dimensions of SC and its relationship to edentulism differed across the five LMICs. Our study highlights the importance of considering contextual factors when analyzing the relationship between SC and oral health. Further research is required to understand how SC influences oral health in LMICs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 5","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12519621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of Endodontic Treatment in Far North Queensland, Australia: A Retrospective Observational Study of 11 Years","authors":"Aditya Suvarna,&nbsp;Preethi Thennarasu,&nbsp;Sona Sojan,&nbsp;Olivia Gables,&nbsp;Daniel J. Browne,&nbsp;Rodrigo R. Amaral","doi":"10.1002/cre2.70232","DOIUrl":"10.1002/cre2.70232","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This retrospective observational study assessed demographics, geographical influences, and diagnostic trends in patients receiving endodontic treatment at James Cook University dental clinics between 2011 and 2022. Patient demographics (sex and age), treatment timing, and care types were examined, with a focus on regional and rural disparities in access to endodontic care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Data were extracted from electronic dental records from 2011 to 2022 using service item codes under the “Endodontics section (codes 411–459)” of the Australian Schedule of Dental Services and Glossary. The Modified Monash Model framework was used to assess geographical disparities in treatment access.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Females sought treatment earlier than males, who often presented later with more severe symptoms. Older males were more likely to present with pulpal necrosis and chronic apical abscesses, whereas females had higher rates of previously initiated endodontic therapy and asymptomatic apical periodontitis. A total of 2932 patients were treated, with tooth 46 being the most treated (7.54%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Significant geographical disparities in endodontic treatment timing exist, with rural and remote patients experiencing delays in treatment. These findings highlight the need for improved access to specialized dental care, particularly in underserved areas.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 5","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12519619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of Palatally Displaced Canines in Children: A Randomized Controlled Pilot Trial on Exposure Time and Patient Perception of Two Closed Surgical Methods","authors":"Katja Hashemi Elses,&nbsp;Krister Bjerklin,&nbsp;Ann-Marie Roos Jansåker,&nbsp;Mikael Sonesson","doi":"10.1002/cre2.70233","DOIUrl":"10.1002/cre2.70233","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate treatment time and patient perception of two surgical methods to expose a palatally displaced canine (PDC) into the oral cavity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>A total of 30 consecutive patients between 11 and 18 years, with maxillary displaced canines were recruited. After gaining informed consent from the patients and custodians, the patients were randomized into two groups by an independent person. Both groups received a chain attached to the crown of the canine: in group A (control group) the chain was placed under the mucoperiosteal flap to an incision on the alveolar crest and in group B (test group), the chain penetrated the mucoperiosteal flap inferiorly to the crown of the canine. Outcome measures where time to expose the PDC into the oral cavity and the patient's experience of pain and discomfort during the treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-six patients full-filled the trial, mean age was 12.9 years, (SD 1.6 years). The time to expose the canines for the control group was 11.9 months (SD 6.5) and for the test group 6.7 months (SD 3.2) The conventional method showed less pain on the day of surgery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The method used in the test group resulted in a 5-month shorter time to expose the canine compared to the control group, and higher pain level on the day of surgery. For generalizability of the results, larger studies are needed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 5","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12516783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145279034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Does the Bonding Strength of Reline Materials and Denture Teeth Vary Between 3D-Printed and Milled Complete Denture Bases? A Systematic Review and Meta-Analysis","authors":"Sarah Arzani,&nbsp;Erfan Khorasani,&nbsp;Aida Mokhlesi,&nbsp;Shima Azadian,&nbsp;Safoura Ghodsi,&nbsp;Seyed Ali Mosaddad","doi":"10.1002/cre2.70234","DOIUrl":"10.1002/cre2.70234","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To systematically compare the bond strength of denture teeth and reline materials to additively manufactured (AM) versus subtractively milled (SM) denture base resins and to identify the material- and process-related factors influencing bonding performance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A systematic electronic search of PubMed, Scopus, Embase, Web of Science, the Cochrane Library, and Google Scholar was conducted up to December 10, 2024. Eligible in vitro studies comparing bond strength at either the tooth–base or reline–base interface using AM and SM denture bases were included. Studies that lacked direct comparison, involved conventional heat-polymerized bases, or did not report quantitative bond strength data were excluded. Meta-analyses were performed using random-effects models, calculating mean differences (MD) for tooth bonding and standardized mean differences (SMD) for reline bonding. Subgroup, sensitivity, and publication bias analyses (Egger's regression and Begg's rank tests) were included. Risk of bias was evaluated using QUIN tools.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Out of 2985 screened records, 20 studies comprising 156 independent comparisons were included; 41 for tooth bonding and 115 for reline bonding. Initial tooth-bonding meta-analysis revealed no significant difference; however, after exclusion of two outlier comparisons identified through sensitivity analysis (<i>n</i> = 39), milled bases demonstrated significantly higher bond strength (MD = −2.43 MPa, 95% CI–3.90 to −0.96; <i>p</i> = 0.001). For reline bonding, AM bases consistently underperformed across all studies, with the pooled estimate favoring milled bases (SMD = −2.62, 95% CI–3.22 to −2.03; <i>p</i> = 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Within the limitations of this review, milled denture bases demonstrate consistently stronger and more reliable bonding to both teeth and reline materials than current printable photopolymer bases.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 5","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The PI3K/AKT/mTOR Pathway and Oral Diseases: A Bibliometric Analysis From 2008 to 2025","authors":"Yena Gan,&nbsp;Duoduo Li,&nbsp;He Xu,&nbsp;Sheng Han,&nbsp;He Zhu,&nbsp;Zening Wei,&nbsp;Zhigang Cai,&nbsp;Jinwei Huang","doi":"10.1002/cre2.70238","DOIUrl":"10.1002/cre2.70238","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The phosphoinositide 3 kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway is a key therapeutic target for oral diseases. This study uses bibliometric analysis to identify research trends, knowledge gaps, and the development of PI3K/AKT/mTOR-targeted therapies.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic literature search was conducted in March 2025 using the keywords “PI3K/AKT/mTOR” and “dental OR oral.” Publication trends, highly cited studies, research hotspots, and emerging trends were analyzed. Comparative analyses of publication year, study design, and disease categories were performed between Asian and non-Asian cohorts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>From 2008 to 2025, 119 studies were identified, with China, India, and Japan leading in publications and citations. Germany had the highest average citations. Keyword analysis showed a shift from basic to clinical research. Of these studies, 91 were from Asia, covering a broader range of oral conditions, while 28 were from non-Asian regions, with no significant differences in study design or disease categories.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This bibliometric analysis shows rising global interest in PI3K/AKT/mTOR research in oral science, led by Asia. Research has shifted from basic signaling to disease-focused studies, with future efforts focusing on underexplored oral pathologies and translational applications, particularly in targeted therapy and regenerative medicine.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 5","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of Cracked Teeth Before, During, and After the Covid-19 Pandemic—A Retrospective Analysis in a German Private General Practice","authors":"Jörg Philipp Tchorz,&nbsp;Patrizia Ladar,&nbsp;Maria Lessani,&nbsp;Sebastian Fitzek","doi":"10.1002/cre2.70239","DOIUrl":"10.1002/cre2.70239","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The Covid-19 pandemic increased stress, which may have led to more bruxism, TMDs, and thus tooth fractures. While previous studies, primarily from specialized clinics, reported an increase in cracked teeth during the pandemic, this retrospective study aimed to assess whether similar trends were observed in a general dental practice in Bavaria, Germany, which remained fully operational throughout the pandemic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Patient records from 2018 to 2023 (<i>n</i> = 4709 patients, 10,018 visits) were analyzed for symptomatic tooth fractures, categorized as wall/cusp fractures, incomplete cracks, or complete fractures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Statistical analysis using the Mann–Whitney <i>U</i> test revealed no significant differences in fracture incidence between pre-pandemic (2018–2019), pandemic (2020–2021), and post-pandemic (2022–2023) periods. Mandibular molars were the most frequently affected teeth (7.94%–12.43%), and composite restorations were most associated with fractures (51.85%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Contrary to previous findings from endodontic practices, this study found no pandemic-related surge in tooth fractures, suggesting that referral bias or patient selection in specialized settings may influence reported trends.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 5","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental Caries Status and Associated Factors Among Adults in Southeastern Iran: Findings From the Zahedan Adult Cohort Study","authors":"Somaye Ansari Moghadam,&nbsp;Razie Keikha Arya,&nbsp;Hassan Okati-Aliabad,&nbsp;Mahdi Mohammadi,&nbsp;Alireza Ansari-Moghaddam","doi":"10.1002/cre2.70236","DOIUrl":"10.1002/cre2.70236","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Dental caries remains a major public health concern globally. This study aimed to assess the dental caries status and its associated factors among adults in Southeastern Iran.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>This cross-sectional study included 10,016 adults aged 35–70 years who participated in the Zahedan Adult Cohort Study (ZACS). The status of dental caries was assessed using the decayed, missing, and filled teeth (DMFT) index. Data on sociodemographic characteristics, oral hygiene practices, presence of oral lesions, current cigarette smoking and drug use, and history of chronic condition were collected through valid questionnaires from the ZACS. One-factor and multifactor general linear models were used to identify significant factors associated with DMFT.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In this study, 99.4% of participants had a DMFT score of 1 or higher, indicating a high lifetime experience of dental caries. The mean DMFT score was 17.3. Additionally, 47.91% of participants had filled teeth (1), and 78.7% had decayed teeth (DT), with the 35–40 age group showing the lowest mean DT score of 3.65. Conversely, individuals over 60 had the highest DMFT score of 22.88. In the multifactor model, DMFT significantly increased with age and decreased with higher education levels. DMFT also decreased from underweight to obese individuals. Furthermore, DMFT significantly decreased with increased daily tooth brushing, while cigarette smokers and drug users exhibited significantly higher DMFT scores.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study revealed significant variations in DMFT scores based on age, education, and oral hygiene practices among adults in Southeastern Iran, highlighting the importance of consistent dental brushing. The findings suggest the need for targeted public health interventions, particularly for smokers, drug users, and less educated populations, to address oral health challenges and reduce dental caries prevalence.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 5","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502622/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145237849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the PowerScope Appliance Effects on the Dentoskeletal and Soft Tissue for the Treatment of Class II Malocclusions","authors":"Neda Babanouri,&nbsp;Roghayeh Baghandeh,&nbsp;Kimia Kiumarsi","doi":"10.1002/cre2.70230","DOIUrl":"10.1002/cre2.70230","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To evaluate and compare the dentoskeletal and soft tissue effects of the PowerScope and Twin Block appliances for treating Class II malocclusions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>This retrospective study analyzed pre- (T0) and posttreatment (T1) cephalograms of 14 patients treated with PowerScope (Group A) and 17 patients treated with Twin Block (Group B). Thirty-three cephalometric variables were assessed. Statistical analysis included paired and independent <i>t</i>-tests or their non-parametric equivalents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Both groups showed significant improvements in soft tissue profiles. The Twin Block group demonstrated a significantly greater increase in SNB angle (<i>p</i> = 0.048) and more pronounced changes in UL-SnPog' and LL-SnPog’ posttreatment (<i>p</i> = 0.021 for both). The PowerScope group exhibited significantly greater increases in IMPA and Md-NB (<i>p</i> = 0.029 and <i>p</i> &lt; 0.001, respectively) and a significantly shorter treatment duration (<i>p</i> &lt; 0.0001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Both appliances effectively treat Class II malocclusion and improve lip positioning. The Twin Block appliance is associated with greater mandibular skeletal advancement, while the PowerScope appliance leads to greater lower incisor protrusion and a shorter treatment time.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10203,"journal":{"name":"Clinical and Experimental Dental Research","volume":"11 5","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12502621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}