Clinics in dermatology最新文献

英文中文

DO and MD enrollment in US dermatology residencies after the graduate medical education merger: Implications for access. 研究生医学教育合并后美国皮肤科住院医师注册DO和MD：对准入的影响。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-11-02 DOI: 10.1016/j.clindermatol.2025.10.013

Lily Park, Sarah Beach, Brad P Glick, Anthony V Benedetto

引用次数: 0

Primary cutaneous mucinoses in connective tissue diseases as a diagnostic and prognostic challenge 结缔组织疾病的原发性皮肤粘液病作为诊断和预后的挑战。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.09.028

Giorgio Stabile MD , Nazario Pesce MD , Giorgia Di Marco MD , Antonio Podo Brunetti MD , Gianmarco Diego Bigotto MD , Stefania Guida MD , Franco Rongioletti MD

Mucin deposition in the skin, a hallmark feature in dermatopathology, is frequently associated with connective tissue diseases such as lupus erythematosus, dermatomyositis, and, to a lesser extent, scleroderma. Although mucin deposition commonly accompanies specific skin lesions in lupus erythematosus, dermatomyositis, and sometimes scleroderma, its occurrence as a distinct clinical manifestation with defining histopathologic features is rare. Such presentations that are classified as primary cutaneous mucinoses not only aid in diagnosis but may also have prognostic implications. This study systematically reviews the literature to evaluate case demographics, clinical characteristics, histologic findings, immunologic markers, and treatment responses of primary cutaneous mucinoses linked to connective tissue diseases. Our findings highlight that mucin deposition exhibits variable presentations and serves as a valuable diagnostic clue, particularly when integrated with other clinical and histopathologic criteria.

Mucin, a high-molecular-weight glycoprotein complex primarily composed of hyaluronic acid, is a standard component of dermal connective tissues. It is produced in small amounts by fibroblasts and mast cells and is known for its high water-holding capacity. Excessive mucin deposition, however, which can occur in certain pathologic states, leads to dermal swelling known as myxedema. Cutaneous mucinosis is often associated with connective tissue diseases, in which mucin deposition can serve as histologic evidence for conditions such as lupus erythematosus (LE) or dermatomyositis (DM), particularly in the appropriate clinical context. Less frequently, mucin is also observed in scleroderma cases.¹^,² Although mucin deposition can accompany specific skin lesions in LE and DM, cases in which it is a prominent and defining histopathologic feature are rare. Such cases classified into the chapter of primary cutaneous mucinoses have diagnostic value and may also serve as prognostic indicators. This review assesses the diagnostic and prognostic significance of primary cutaneous mucinoses associated with connective tissue diseases.

皮肤中的粘蛋白沉积是皮肤病理学的一个标志性特征，通常与结缔组织疾病如红斑狼疮（LE）、皮肌炎（DM）以及在较小程度上与硬皮病有关。尽管粘蛋白沉积通常伴随着LE、DM和硬皮病的特定皮肤病变，但其作为明确的组织病理学特征的独特临床表现是罕见的。这些被归类为原发性皮肤粘液病的表现不仅有助于诊断，而且可能具有预后意义。本研究系统地回顾文献，以评估与结缔组织疾病相关的原发性皮肤粘液病的病例人口统计学、临床特征、组织学表现、免疫标志物和治疗反应。我们的研究结果强调粘蛋白沉积表现出不同的表现，并作为一种有价值的诊断线索，特别是当与其他临床和组织病理学标准相结合时。

{"title":"Primary cutaneous mucinoses in connective tissue diseases as a diagnostic and prognostic challenge","authors":"Giorgio Stabile MD , Nazario Pesce MD , Giorgia Di Marco MD , Antonio Podo Brunetti MD , Gianmarco Diego Bigotto MD , Stefania Guida MD , Franco Rongioletti MD","doi":"10.1016/j.clindermatol.2025.09.028","DOIUrl":"10.1016/j.clindermatol.2025.09.028","url":null,"abstract":"<div><div>Mucin deposition in the skin, a hallmark feature in dermatopathology, is frequently associated with connective tissue diseases such as lupus erythematosus, dermatomyositis, and, to a lesser extent, scleroderma. Although mucin deposition commonly accompanies specific skin lesions in lupus erythematosus, dermatomyositis, and sometimes scleroderma, its occurrence as a distinct clinical manifestation with defining histopathologic features is rare. Such presentations that are classified as primary cutaneous mucinoses not only aid in diagnosis but may also have prognostic implications. This study systematically reviews the literature to evaluate case demographics, clinical characteristics, histologic findings, immunologic markers, and treatment responses of primary cutaneous mucinoses linked to connective tissue diseases. Our findings highlight that mucin deposition exhibits variable presentations and serves as a valuable diagnostic clue, particularly when integrated with other clinical and histopathologic criteria.</div><div>Mucin, a high-molecular-weight glycoprotein complex primarily composed of hyaluronic acid, is a standard component of dermal connective tissues. It is produced in small amounts by fibroblasts and mast cells and is known for its high water-holding capacity. Excessive mucin deposition, however, which can occur in certain pathologic states, leads to dermal swelling known as myxedema. Cutaneous mucinosis is often associated with connective tissue diseases, in which mucin deposition can serve as histologic evidence for conditions such as lupus erythematosus (LE) or dermatomyositis (DM), particularly in the appropriate clinical context. Less frequently, mucin is also observed in scleroderma cases.<span><span><sup>1</sup></span></span><sup>,</sup><span><span><sup>2</sup></span></span> Although mucin deposition can accompany specific skin lesions in LE and DM, cases in which it is a prominent and defining histopathologic feature are rare. Such cases classified into the chapter of primary cutaneous mucinoses have diagnostic value and may also serve as prognostic indicators. This review assesses the diagnostic and prognostic significance of primary cutaneous mucinoses associated with connective tissue diseases.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"43 6","pages":"Pages 810-827"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tadeusz Stępniewski: Polish dermatologist and “Righteous Among the Nations” Tadeusz stepeniewski：波兰皮肤科医生和“正义的国家”。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.09.023

Sophie Walter BMed, MD, BSc(Med) (Hons)

This presentation presents the life and career of Tadeusz Stępniewski (1905-1987), a Polish dermatologist awarded the title “Righteous Among the Nations” for his bravery saving Jews during the Holocaust, collates information about other dermatologists who have also received the title and reflects on the place of virtue in the profession. Various sources were used to provide information about Stępniewski, including copies of materials held by the Archives Department of Yad Vashem, Israel’s Holocaust memorial authority. At the outbreak of World War II, Stępniewski had a private dermatology practice in central Warsaw and was affiliated with the Skin and Venereal Diseases Clinic at the University of Warsaw. During the German occupation, he assisted Jews by helping them escape from the Warsaw ghetto, hiding them in various locations, providing dermatologic care and other medical treatments, contributing to an underground medical publication, and giving financial aid. Stępniewski is one of seven dermatologists who have received the Righteous Among the Nations title. Their heroic deeds bring to the forefront the role of virtue in all aspects of the lives of dermatologists and other medical professionals.

Tadeusz Stepniewski（1905-1987）是一位波兰皮肤科医生，因其在大屠杀期间拯救犹太人的英勇行为而被授予“国际正义”称号，他的生活和职业生涯整理了其他获得该称号的皮肤科医生的信息，并反思了美德在该职业中的地位。提供关于斯特普涅夫斯基的信息使用了各种来源，包括以色列大屠杀纪念机构亚德瓦谢姆档案馆持有的材料副本。第二次世界大战爆发时，斯特普涅夫斯基在华沙市中心开了一家私人皮肤科诊所，隶属于华沙大学的皮肤和性病诊所。在德国占领期间，他帮助犹太人逃离华沙隔都，把他们藏在不同的地方，提供皮肤护理和其他医疗服务，为地下医学出版物撰稿，并提供经济援助。斯蒂芬尼夫斯基是七位获得“国际正义”称号的皮肤科医生之一。他们的英雄事迹使美德在皮肤科医生和其他医疗专业人员生活的各个方面发挥了重要作用。

{"title":"Tadeusz Stępniewski: Polish dermatologist and “Righteous Among the Nations”","authors":"Sophie Walter BMed, MD, BSc(Med) (Hons)","doi":"10.1016/j.clindermatol.2025.09.023","DOIUrl":"10.1016/j.clindermatol.2025.09.023","url":null,"abstract":"<div><div>This presentation presents the life and career of Tadeusz Stępniewski (1905-1987), a Polish dermatologist awarded the title “Righteous Among the Nations” for his bravery saving Jews during the Holocaust, collates information about other dermatologists who have also received the title and reflects on the place of virtue in the profession. Various sources were used to provide information about Stępniewski, including copies of materials held by the Archives Department of Yad Vashem, Israel’s Holocaust memorial authority. At the outbreak of World War II, Stępniewski had a private dermatology practice in central Warsaw and was affiliated with the Skin and Venereal Diseases Clinic at the University of Warsaw. During the German occupation, he assisted Jews by helping them escape from the Warsaw ghetto, hiding them in various locations, providing dermatologic care and other medical treatments, contributing to an underground medical publication, and giving financial aid. Stępniewski is one of seven dermatologists who have received the Righteous Among the Nations title. Their heroic deeds bring to the forefront the role of virtue in all aspects of the lives of dermatologists and other medical professionals.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"43 6","pages":"Pages 772-782"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early history of gender reassignment surgery in Prussia and Saxony 普鲁士和萨克森性别重置手术的早期历史。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.07.008

Uwe Wollina MD , Leonard J. Hoenig MD , Lawrence Charles Parish MD, MD (Hon), FRCP (Edin)

This contribution provides a note on the early days of gender reassignment surgery, which was pioneered by Felix Abraham, Erwin Gohrbrandt, Ludwig Levy-Lenz, and Kurt Warnekros need dates during the 1920s. Their experimental surgeries would gain significant attention through the mass media. Such reassignment surgery has been illustrated by the life and death of Danish painter Einar Wegener (1882-1931), who underwent several gender reassignment surgeries. The narratives of his life are discussed with the views of medical progress made from the early 20th century until now.

这篇文章提供了一份关于性别重置手术早期的笔记，这项手术是由费利克斯·亚伯拉罕、欧文·高布兰特、路德维希·莱维-伦茨和库尔特·沃内克罗斯在20世纪20年代首创的。他们的实验性手术通过大众媒体获得了极大的关注。丹麦画家艾纳·韦格纳（Einar Wegener, 1882-1931）接受了多次性别重新分配手术，他的生与死就说明了这种重新分配手术。从20世纪初到现在，他的生活叙述与医学进步的观点进行了讨论。

引用次数: 0

Rethinking research metrics in dermatology and beyond 重新思考皮肤病学及其他领域的研究指标。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.08.002

Waseem Hassan PhD , Fred Paas PhD

Assessing academic performance in dermatology is an interesting and evolving challenge. Early-career researchers often look for clear indicators to identify leading authors; however, reliance on single measures such as citation counts or the h-index provides only a limited view of scholarly influence. Using diverse bibliometric indicators from Scopus, we observed that author rankings shifted considerably depending on the metric applied, reflecting the lack of agreement on how best to capture academic impact. Similarly, we noted that ethical publications (letters, notes, and related formats) in dermatology may contribute to scholarly discussions and institutional practices but often receive modest citation profiles, highlighting the gap between measurable indicators and genuine value. Inflated authorship practices and citation manipulation further complicate fair evaluation. Fractional authorship models and multidimensional frameworks that consider publication type, journal quality, collaboration, funding strength, and broader societal contributions may offer more balanced perspectives. We suggest that institutions, journals, and training programs promote the ethical use of metrics and integrate qualitative assessments alongside quantitative ones. Such an approach can foster fairness, transparency, and meaningful recognition within dermatology and academic medicine more broadly.

评估皮肤科的学术表现是一个有趣的和不断发展的挑战。早期职业研究人员经常寻找明确的指标来确定主要作者；然而，对引用数或h指数等单一指标的依赖只能提供有限的学术影响观点。通过使用来自Scopus的各种文献计量指标，我们观察到作者排名根据所采用的度量标准发生了很大的变化，这反映了在如何最好地捕捉学术影响方面缺乏共识。同样，我们注意到，皮肤病学的伦理出版物（信件、笔记和相关格式）可能有助于学术讨论和机构实践，但往往得到适度的引用，突出了可测量指标与真正价值之间的差距。夸大作者身份和引文操纵进一步使公平评价复杂化。部分作者模型和多维框架——考虑出版类型、期刊质量、合作、资金实力和更广泛的社会贡献——可能提供更平衡的观点。我们建议机构、期刊和培训项目促进指标的道德使用，并将定性评估与定量评估结合起来。这种方法可以促进皮肤病学和学术医学更广泛的公平、透明和有意义的认可。

{"title":"Rethinking research metrics in dermatology and beyond","authors":"Waseem Hassan PhD , Fred Paas PhD","doi":"10.1016/j.clindermatol.2025.08.002","DOIUrl":"10.1016/j.clindermatol.2025.08.002","url":null,"abstract":"<div><div>Assessing academic performance in dermatology is an interesting and evolving challenge. Early-career researchers often look for clear indicators to identify leading authors; however, reliance on single measures such as citation counts or the h-index provides only a limited view of scholarly influence. Using diverse bibliometric indicators from Scopus, we observed that author rankings shifted considerably depending on the metric applied, reflecting the lack of agreement on how best to capture academic impact. Similarly, we noted that ethical publications (letters, notes, and related formats) in dermatology may contribute to scholarly discussions and institutional practices but often receive modest citation profiles, highlighting the gap between measurable indicators and genuine value. Inflated authorship practices and citation manipulation further complicate fair evaluation. Fractional authorship models and multidimensional frameworks that consider publication type, journal quality, collaboration, funding strength, and broader societal contributions may offer more balanced perspectives. We suggest that institutions, journals, and training programs promote the ethical use of metrics and integrate qualitative assessments alongside quantitative ones. Such an approach can foster fairness, transparency, and meaningful recognition within dermatology and academic medicine more broadly.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"43 6","pages":"Pages 865-867"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A collection of saints for sufferers of skin diseases 《皮肤病患者圣徒集》。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.09.022

Uwe Wollina MD , Leonard J. Hoenig MD , Lawrence Charles Parish MD, MD (Hon), FRCP (Edin)

Religion has long served as a means to avoid disease and death or to come to terms with the inevitable. Patron saints to protect against disease and to offer a miraculous cure have been adopted in the Christian world since medieval times. The invocation of saints in need and danger is one of the most intrinsic, traditional characteristics of popular piety. More than 14 saints are known as patrons of those who suffer from skin and venereal diseases. We provide an overview of several major saints with a connection to dermatology. Although women were not uncommon among the healers of the period, women saints are very rare, reflecting the traditional medieval patriarchal order.

长期以来，宗教一直是避免疾病和死亡或接受不可避免的事情的一种手段。自中世纪以来，基督教世界一直采用守护神来预防疾病并提供奇迹般的治疗。在需要和危险中对圣人的祈求是大众虔诚最内在、最传统的特征之一。超过14位圣人被认为是皮肤和全身疾病患者的保护人。我们提供了几个主要的圣人与皮肤科的连接的概述。虽然女性在这一时期的治疗师中并不罕见，但女性圣徒却非常罕见，这反映了传统的中世纪父权秩序。

引用次数: 0

Comment on “Beyond beauty: Neurocosmetics, the skin-brain axis, and the future of emotionally intelligent skincare” 评论“超越美丽：神经化妆品、皮肤-大脑轴和情商护肤的未来”。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.10.001

S. Dhanya Dedeepya MD, Vaishali Goel PhD, Nivedita Nikhil Desai MD

引用次数: 0

Lymphocytic and granulomatous cutaneous small-vessel vasculitis after polyadenosine diphosphate–ribose polymerase inhibitor therapy PARP抑制剂治疗后淋巴细胞性和肉芽肿性皮肤小血管炎。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.09.021

Carla Stephan MD , Cynthia Magro MD

Olaparib is a polyadenosine diphosphate–ribose polymerase (PARP) inhibitor that is used in the treatment of advanced ovarian cancer. PARP inhibitors result in the accumulation of single-strand DNA breaks that are toxic to tumor cells. PARP inhibition with a concomitant Breast cancer susceptibility gene (BRCA) mutation results in what is known as synthetic lethality to the tumor cells. Cutaneous adverse effects have been reported with PARP inhibition, namely pruritus, photosensitivity reactions, edema, vasculitis, and panniculitis. We present a case of a 36-year-old woman who developed dermatitis on the bilateral lower extremities one month after starting olaparib for advanced ovarian carcinoma. A punch biopsy taken from the eruption was consistent with a lymphocytic and granulomatous small-vessel vasculitis with a component of lobular panniculitis. The exact pathogenic mechanism of vasculitis and panniculitis in the setting of a PARP inhibitor is unclear. Given the multiple functions of PARP at the cellular level, it is not surprising that the inhibition of this superfamily may result in adverse effects. In particular, the inhibition of PARP has been shown to alter the inflammatory milieu from a Th2 predominance to a Th1 predominance. This shift in polarization may play a role in the development of vasculitis and panniculitis in such patients.

奥拉帕尼是一种聚腺苷二磷酸核糖聚合酶（PARP）抑制剂，用于治疗晚期卵巢癌。PARP抑制剂导致单链DNA断裂的积累，这对肿瘤细胞是有毒的。PARP抑制与伴随的BRCA突变导致对肿瘤细胞的合成致死。PARP抑制已报道皮肤不良反应，即瘙痒、光敏反应、水肿、血管炎和泛膜炎。我们提出了一个36岁的女性谁在开始奥拉帕尼治疗晚期卵巢癌一个月后出现双侧下肢皮疹的情况。从皮疹上取的穿刺活检符合淋巴细胞性和肉芽肿性小血管炎，伴有小叶性血管炎的成分。PARP抑制剂作用下血管炎和泛膜炎的确切致病机制尚不清楚。考虑到PARP在细胞水平上的多种功能，抑制这个超家族可能会导致不良反应也就不足为奇了。特别是，PARP的抑制已被证明可以改变炎症环境，从Th2为主转变为Th1为主。这种极化的转变可能在这些患者的血管炎和泛膜炎的发展中起作用。

{"title":"Lymphocytic and granulomatous cutaneous small-vessel vasculitis after polyadenosine diphosphate–ribose polymerase inhibitor therapy","authors":"Carla Stephan MD , Cynthia Magro MD","doi":"10.1016/j.clindermatol.2025.09.021","DOIUrl":"10.1016/j.clindermatol.2025.09.021","url":null,"abstract":"<div><div>Olaparib is a polyadenosine diphosphate–ribose polymerase (PARP) inhibitor that is used in the treatment of advanced ovarian cancer. PARP inhibitors result in the accumulation of single-strand DNA breaks that are toxic to tumor cells. PARP inhibition with a concomitant Breast cancer susceptibility gene (BRCA) mutation results in what is known as synthetic lethality to the tumor cells. Cutaneous adverse effects have been reported with PARP inhibition, namely pruritus, photosensitivity reactions, edema, vasculitis, and panniculitis. We present a case of a 36-year-old woman who developed dermatitis on the bilateral lower extremities one month after starting olaparib for advanced ovarian carcinoma. A punch biopsy taken from the eruption was consistent with a lymphocytic and granulomatous small-vessel vasculitis with a component of lobular panniculitis. The exact pathogenic mechanism of vasculitis and panniculitis in the setting of a PARP inhibitor is unclear. Given the multiple functions of PARP at the cellular level, it is not surprising that the inhibition of this superfamily may result in adverse effects. In particular, the inhibition of PARP has been shown to alter the inflammatory milieu from a Th2 predominance to a Th1 predominance. This shift in polarization may play a role in the development of vasculitis and panniculitis in such patients.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"43 6","pages":"Pages 762-765"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reflections on The Thing’s rocklike skin 对这东西岩石般的皮肤的思考。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.09.033

Leonard J. Hoenig MD , Uwe Wollina MD , Lawrence Charles Parish MD, MD (Hon), FRCP (Edin)

The Thing is a Marvel Comics superhero who sports rocklike skin. This contribution describes The Thing’s cutaneous features and explores similar rocky exteriors in the Stone Giants and other stony creatures described in legends, folklore, and fiction. In the real world, some animals resemble rocks and stones, such as the rock hyrax, stone fish, Pyura chilensis, and common toad. There are also children suffering from stiff skin syndrome, a rare genetic disorder that causes their skin to become stony-hard. The clinical features of this syndrome are highlighted in this contribution.

The Thing是漫威漫画中的超级英雄，有着岩石般的皮肤。这篇文章描述了怪物的皮肤特征，并探索了石巨人和其他传说、民间传说和小说中描述的石质生物的类似岩石外观。在现实世界中，有些动物长得很像岩石和石头，比如岩兔、石鱼、赤足和普通蟾蜍。还有一些儿童患有皮肤僵硬综合症，这是一种罕见的遗传性疾病，会导致他们的皮肤变得像石头一样坚硬。该综合征的临床特征在本贡献中得到强调。

引用次数: 0

Epidemics on glass paintings 流行的玻璃画。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.09.020

Uwe Wollina MD , Leonard J. Hoenig MD , Lawrence Charles Parish MD, MD (Hon), FRCP (Edin)

Clinical Dermatology and Fine Arts share a mutual interest in detailed observations. Although there are several contributions about skin diseases in paintings, communications about skin disease and painted glass are sparse. Glass is a complex material with the refinement of colors being limited when compared with oil paintings. Glass paintings are limited to two surfaces, where the paint dries quickly in contrast to canvas or wood. We discuss several examples of medieval and contemporary art. Major themes in medieval times were the plague and leprosy, whereas more recently, contemporary artists have often selected such pandemic diseases as COVID-19 for their subjects.

临床皮肤病学和美术在详细观察方面有共同的兴趣。虽然有一些关于绘画中皮肤病的贡献，但关于皮肤病和彩绘玻璃的交流很少。玻璃是一种复杂的材料，与油画相比，颜色的精细程度受到限制。玻璃画仅限于两个表面，与帆布或木头相比，油漆干得很快。我们将讨论几个中世纪和当代艺术的例子。中世纪的主要主题是瘟疫和麻风病，而最近，当代艺术家经常选择像COVID-19这样的大流行疾病作为主题。

引用次数: 0

首页上一页

下一页尾页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Clinics in dermatology

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀