Clinics in dermatology最新文献

英文中文

Dermatology misinformation on the Chinese social media platform known as RedNote/Xiaohongshu 中国社交媒体平台红笔记/小红书上的皮肤病错误信息。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2026-01-01 Epub Date: 2025-09-13 DOI: 10.1016/j.clindermatol.2025.09.003

Tsz Lam , Uwe Wollina MD , Leonard J. Hoenig MD , Lawrence Charles Parish MD, MD (Hon), FRCP (Edin)

Social media has led to the proliferation of accessible health and dermatologic advice; however, it has also permitted the spread of misinformation. We have examined the prevalence of dermatologic misinformation on the popular Chinese social media and e-commerce platform Xiaohongshu (RedNote), which has a notable and significant impact on Western audiences. Through an analysis of the digital content and media posts on RedNote as well as an examination of related scientific literature, this study identifies and reviews distinct examples of dermatology advice promoted by the RedNote platform. Key findings highlight the combination of aggressive ingredients, irregular homemade treatments, and the endorsement of alarming beauty procedures. Algorithmically structured platforms like RedNote prioritize online engagement over factual evidence. When merged with the consumer-oriented culture and the necessary high beauty standards, the result fosters an environment where false information can expand and thrive. Our analysis revealed a public health concern where social platforms and influencer culture contribute to cutaneous health hazards. We have proposed some practical solutions, emphasizing the importance of elevated media literacy among social community spaces and vocalized professional intervention. These measures should mitigate the harmful consequences originating from online misinformation.

社交媒体导致了健康和皮肤病学咨询的普及；然而，它也允许了错误信息的传播。我们调查了流行的中国社交媒体和电子商务平台小红书（RedNote）上皮肤病学错误信息的流行程度，这些信息对西方受众产生了显著而显著的影响。通过对RedNote上的数字内容和媒体帖子的分析，以及对相关科学文献的研究，本研究确定并回顾了RedNote平台推广的皮肤病学建议的不同例子。主要研究结果强调了攻击性成分、不规律的家庭护理和令人担忧的美容程序的认可的结合。像RedNote这样的算法结构化平台优先考虑在线参与，而不是事实证据。当与以消费者为导向的文化和必要的高审美标准相结合时，这就形成了一个虚假信息可以扩大和繁荣的环境。我们的分析揭示了社交平台和网红文化对皮肤健康危害的公共健康问题。我们提出了一些实用的解决方案，强调在社会社区空间中提高媒体素养和专业干预的重要性。这将减轻网络错误信息带来的有害后果。

{"title":"Dermatology misinformation on the Chinese social media platform known as RedNote/Xiaohongshu","authors":"Tsz Lam , Uwe Wollina MD , Leonard J. Hoenig MD , Lawrence Charles Parish MD, MD (Hon), FRCP (Edin)","doi":"10.1016/j.clindermatol.2025.09.003","DOIUrl":"10.1016/j.clindermatol.2025.09.003","url":null,"abstract":"<div><div>Social media has led to the proliferation of accessible health and dermatologic advice; however, it has also permitted the spread of misinformation. We have examined the prevalence of dermatologic misinformation on the popular Chinese social media and e-commerce platform Xiaohongshu (RedNote), which has a notable and significant impact on Western audiences. Through an analysis of the digital content and media posts on RedNote as well as an examination of related scientific literature, this study identifies and reviews distinct examples of dermatology advice promoted by the RedNote platform. Key findings highlight the combination of aggressive ingredients, irregular homemade treatments, and the endorsement of alarming beauty procedures. Algorithmically structured platforms like RedNote prioritize online engagement over factual evidence. When merged with the consumer-oriented culture and the necessary high beauty standards, the result fosters an environment where false information can expand and thrive. Our analysis revealed a public health concern where social platforms and influencer culture contribute to cutaneous health hazards. We have proposed some practical solutions, emphasizing the importance of elevated media literacy among social community spaces and vocalized professional intervention. These measures should mitigate the harmful consequences originating from online misinformation.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"44 1","pages":"Pages 122-131"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145069209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Donovanosis 第五性病。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2026-01-01 Epub Date: 2025-09-26 DOI: 10.1016/j.clindermatol.2025.09.007

Nigel O’Farrell MD, FRCP

Donovanosis usually causes genital ulcers with a distinct clinical appearance. The condition has been a problem in many developing countries, but recent years have seen a significant global decline in prevalence. It is well on the way to being eradicated. Donovanosis has been known under many different terminologies, and there is still debate about how the causative organism should be classified. Recent news agency and social media reports of an increase in the “flesh-eating infection donovanosis” have been false and unhelpful, only leading to hyperbole and increased stigma among those infected.

Donovanosis is a progressive, mildly infectious bacterial infection usually involving the genital area. The causative organism is a gram-negative bacillus, Calymmatobacterium granulomatis. A proposal that the organism be reclassified as Klebsiella granulomatis comb nov was put forward in 1999; however, a consensus is yet to be reached about the definitive nomenclature of the causative agent.¹

多诺瓦病通常引起生殖器溃疡，具有明显的临床表现。这种情况在许多发展中国家都是一个问题，但近年来全球患病率已显著下降。它正在被彻底根除。多诺万病有许多不同的术语，关于致病生物应该如何分类仍然存在争议。最近新闻机构和社交媒体关于“肉食性感染多诺瓦病”增加的报道是虚假和无益的，只会导致夸大，并增加感染者的耻辱感。

引用次数: 0

Updates on Kaposi sarcoma 卡波西肉瘤最新进展

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2026-01-01 Epub Date: 2025-09-24 DOI: 10.1016/j.clindermatol.2025.09.013

Kyaw Zin Htet BA , Eman Bahrani MD , Kieron S. Leslie MB, BS, FRCP

Kaposi sarcoma (KS) is an angioproliferative tumor that is associated with human herpesvirus 8 or Kaposi sarcoma-associated herpes virus infection. KS typically presents in the skin as isolated or multiple, violaceous macules or papulonodular lesions or plaques. The four different KS clinical categories—classic, endemic, epidemic, or AIDS-related and iatrogenic KS—are heterogeneous in epidemiology, manifestations, and complications. Clinical features, diagnostic modalities, and therapeutic regimens for all types of KS are summarized in this review. It is important for clinicians to promptly recognize and approach the treatment of KS in a multidisciplinary fashion for optimal therapeutic outcomes. Newer targeted therapies based on its pathogenesis are being studied.

Kaposi sarcoma (KS) is a vascular tumor associated with human herpesvirus 8 (HHV-8), also known as Kaposi sarcoma-associated herpesvirus (KSHV) infection. KS was first documented in 1872 by Moritz Kaposi, (1837-1902) a Hungarian dermatologist and physician, who described five cases of an atypical tumor that primarily affected the skin of the lower extremities of elderly men.¹ He described the tumors as “idiopathic multiple pigmented sarcoma of the skin,” and this form of the disease later became known as sporadic or classic KS.¹

卡波西肉瘤（KS）是一种血管增生性肿瘤，与人类疱疹病毒8 （HHV-8）或卡波西肉瘤相关疱疹病毒（KSHV）感染有关。KS通常在皮肤上表现为孤立或多发的紫色斑疹或丘疹样病变或斑块。典型性KS、地方性KS、流行或艾滋病相关KS和医源性KS这四种不同的临床类型在流行病学、表现和并发症方面具有异质性。本文综述了各种类型KS的临床特点、诊断方式和治疗方案。对于临床医生来说，及时认识到并以多学科的方式治疗KS是很重要的，以获得最佳的治疗结果。基于其发病机制的新的靶向治疗正在研究中。

{"title":"Updates on Kaposi sarcoma","authors":"Kyaw Zin Htet BA , Eman Bahrani MD , Kieron S. Leslie MB, BS, FRCP","doi":"10.1016/j.clindermatol.2025.09.013","DOIUrl":"10.1016/j.clindermatol.2025.09.013","url":null,"abstract":"<div><div>Kaposi sarcoma (KS) is an angioproliferative tumor that is associated with human herpesvirus 8 or Kaposi sarcoma-associated herpes virus infection. KS typically presents in the skin as isolated or multiple, violaceous macules or papulonodular lesions or plaques. The four different KS clinical categories—classic, endemic, epidemic, or AIDS-related and iatrogenic KS—are heterogeneous in epidemiology, manifestations, and complications. Clinical features, diagnostic modalities, and therapeutic regimens for all types of KS are summarized in this review. It is important for clinicians to promptly recognize and approach the treatment of KS in a multidisciplinary fashion for optimal therapeutic outcomes. Newer targeted therapies based on its pathogenesis are being studied.</div><div>Kaposi sarcoma (KS) is a vascular tumor associated with human herpesvirus 8 (HHV-8), also known as Kaposi sarcoma-associated herpesvirus (KSHV) infection. KS was first documented in 1872 by Moritz Kaposi, (1837-1902) a Hungarian dermatologist and physician, who described five cases of an atypical tumor that primarily affected the skin of the lower extremities of elderly men.<span><span><sup>1</sup></span></span> He described the tumors as “idiopathic multiple pigmented sarcoma of the skin,” and this form of the disease later became known as sporadic or classic KS.<span><span><sup>1</sup></span></span></div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"44 1","pages":"Pages 67-77"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145174020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rising retractions in dermatology (2006-2024): Causes, geographic disparities, and post-retraction citation risk 皮肤科论文撤稿上升（2006-2024）：原因、地域差异和撤稿后引用风险

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2026-01-01 Epub Date: 2025-10-30 DOI: 10.1016/j.clindermatol.2025.10.008

Lu Yuan MD , Daohuan Kang MD , Jia Feng MD , Jiao Zhan MD , Kai Jin MD, PhD , Andrzej Grzybowski MD, PhD

We analyzed dermatology retraction trends (2006-2024) by examining causes, geographic distribution, journal metrics, and citation patterns. Our purpose was to identify systemic issues and propose solutions to enhance research integrity and mitigate postretraction citation risks in the field. A bibliometric analysis was conducted on 280 retracted dermatology contributions from the Retraction Database (2006-2024), supplemented by Scopus for publication and citation data. The annual number of retractions showed a highly significant increase over the period, peaking at 74 in 2023. Academic misconduct (data fabrication/tampering and plagiarism) was the leading cause, accounting for 45% of all retractions. United States had the highest absolute count (n = 80), whereas China exhibited the highest normalized retraction rate (357 per 10,000 publications), contrasting sharply with the US rate (19.7 per 10,000). Postretraction citation analysis (n = 80 contributions) revealed a high proportion of inappropriate citations (30%). The sharply increasing retraction trend, driven largely by misconduct and geographic disparities, requires urgent, multilevel interventions, including stricter oversight, ethical training, and improved peer review. Addressing postretraction citations is critical to curbing misinformation.

我们通过检查原因、地理分布、期刊指标和引用模式，分析了皮肤病学撤回趋势（2006-2024）。我们的目的是确定系统性问题，并提出解决方案，以提高研究的完整性，降低该领域的撤稿后被引风险。对撤稿数据库（2006-2024）中的280篇皮肤病学撤稿论文进行文献计量学分析，并辅以Scopus的出版和引文数据。在此期间，年度撤稿数量大幅增加，2023年达到74篇的峰值。学术不端行为（数据伪造/篡改和剽窃）是主要原因，占所有撤稿的45%。虽然美国的绝对撤稿率最高（n=80），但中国的标准化撤稿率最高（每万篇论文357篇），与美国的撤稿率（每万篇19.7篇）形成鲜明对比。撤稿后引文分析（n=80篇文章）显示，不恰当引文的比例很高（30%）。撤稿趋势急剧增加，这主要是由不当行为和地域差异造成的，需要紧急的多层次干预，包括更严格的监督、道德培训和改进的同行评审。解决撤稿后引用问题对于遏制错误信息至关重要。

{"title":"Rising retractions in dermatology (2006-2024): Causes, geographic disparities, and post-retraction citation risk","authors":"Lu Yuan MD , Daohuan Kang MD , Jia Feng MD , Jiao Zhan MD , Kai Jin MD, PhD , Andrzej Grzybowski MD, PhD","doi":"10.1016/j.clindermatol.2025.10.008","DOIUrl":"10.1016/j.clindermatol.2025.10.008","url":null,"abstract":"<div><div>We analyzed dermatology retraction trends (2006-2024) by examining causes, geographic distribution, journal metrics, and citation patterns. Our purpose was to identify systemic issues and propose solutions to enhance research integrity and mitigate postretraction citation risks in the field. A bibliometric analysis was conducted on 280 retracted dermatology contributions from the Retraction Database (2006-2024), supplemented by Scopus for publication and citation data. The annual number of retractions showed a highly significant increase over the period, peaking at 74 in 2023. Academic misconduct (data fabrication/tampering and plagiarism) was the leading cause, accounting for 45% of all retractions. United States had the highest absolute count (n = 80), whereas China exhibited the highest normalized retraction rate (357 per 10,000 publications), contrasting sharply with the US rate (19.7 per 10,000). Postretraction citation analysis (n = 80 contributions) revealed a high proportion of inappropriate citations (30%). The sharply increasing retraction trend, driven largely by misconduct and geographic disparities, requires urgent, multilevel interventions, including stricter oversight, ethical training, and improved peer review. Addressing postretraction citations is critical to curbing misinformation.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"44 1","pages":"Pages 100-103"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145421317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dermatologic conditions and stigma: The depiction of acne in cartoons 皮肤病和病耻感：漫画中痤疮的描述。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2026-01-01 Epub Date: 2025-10-29 DOI: 10.1016/j.clindermatol.2025.10.012

Sophie Walter BMed, MD, BSc(Med) (Hons)

Acne affects almost 10% of the world’s population, and sufferers are often stigmatized; yet, media portrayals of the condition have received little academic attention. Media depictions can shape public views about medical disorders. This study examined the portrayal of acne in readily accessible cartoons to creatively inform education campaigns about the condition. The image sections of various internet search engines and the online cartoon library CartoonStock were inspected for single-panel cartoons that made specific reference to acne. Each cartoon was then examined according to an instrument with categories for describing the themes about acne, the suggested etiology, treatment methods, and outcome. Ninety-three cartoons were identified. Common themes included acne causing despair for sufferers, being fervently hidden from others, and impairing the formation of intimate relationships. No cartoon made reference to retinoids or other newer acne treatments, and positive outcomes were rarely depicted. It is hoped that future cartoon portrayals of acne may be able to offer more optimistic messages about the condition.

痤疮影响着世界上近10%的人口，患者经常被污名化；然而，媒体对这种情况的描述几乎没有得到学术界的关注。媒体的描述可以塑造公众对医学疾病的看法。这项研究检查了容易接近的漫画中痤疮的写照，以便告知创造性的教育活动关于这种情况。图像部分的各种互联网搜索引擎和在线卡通图书馆卡通股票®检查了单面板漫画，具体涉及痤疮。然后根据描述痤疮主题、建议的病因、治疗方法和结果的工具分类检查每个漫画。确定了94幅漫画。常见的主题包括痤疮，它会让患者感到绝望，但却极力隐藏起来，损害亲密关系的形成。没有漫画提到类维生素a或其他较新的痤疮治疗方法，而且很少描绘积极的结果。人们希望未来关于痤疮的卡通形象能够提供更多乐观的信息。

{"title":"Dermatologic conditions and stigma: The depiction of acne in cartoons","authors":"Sophie Walter BMed, MD, BSc(Med) (Hons)","doi":"10.1016/j.clindermatol.2025.10.012","DOIUrl":"10.1016/j.clindermatol.2025.10.012","url":null,"abstract":"<div><div>Acne affects almost 10% of the world’s population, and sufferers are often stigmatized; yet, media portrayals of the condition have received little academic attention. Media depictions can shape public views about medical disorders. This study examined the portrayal of acne in readily accessible cartoons to creatively inform education campaigns about the condition. The image sections of various internet search engines and the online cartoon library CartoonStock were inspected for single-panel cartoons that made specific reference to acne. Each cartoon was then examined according to an instrument with categories for describing the themes about acne, the suggested etiology, treatment methods, and outcome. Ninety-three cartoons were identified. Common themes included acne causing despair for sufferers, being fervently hidden from others, and impairing the formation of intimate relationships. No cartoon made reference to retinoids or other newer acne treatments, and positive outcomes were rarely depicted. It is hoped that future cartoon portrayals of acne may be able to offer more optimistic messages about the condition.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"44 1","pages":"Pages 179-182"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145421364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The dermatologic aspects of sexually transmitted infections and human immunodeficiency virus: Part II 性传播感染和艾滋病毒的皮肤病学方面：第二部分。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2026-01-01 Epub Date: 2025-09-23 DOI: 10.1016/j.clindermatol.2025.09.005

Christopher B. Bunker MA, MD, FRCP , David A. Hawkins BSc, MBBS, FRCP

引用次数: 0

Innovations and Insights from the 16th World Congress of the International Academy of Cosmetic Dermatology held in Budapest, Hungary, June 26 to 28, 2025 2025年6月26日至28日在匈牙利布达佩斯举行的第16届国际美容皮肤科学会世界大会的创新和见解。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2026-01-01 Epub Date: 2025-09-20 DOI: 10.1016/j.clindermatol.2025.09.004

Vesna Petronic-Rosic MD, MSc, MBA , Norbert Kiss MD, PhD

引用次数: 0

Lymphogranuloma venereum, an invasive and destructive sexually transmitted infection with many faces 性病性淋巴肉芽肿是一种侵袭性、破坏性的性传播感染，具有多面性。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2026-01-01 Epub Date: 2025-09-30 DOI: 10.1016/j.clindermatol.2025.09.009

Henry J.C. de Vries MD, PhD

Lymphogranuloma venereum (LGV) is a serious, invasive, ulcerative sexually transmitted infection caused by Chlamydia trachomatis serovar L1, L2, and L3. Until 2003, we saw LGV among the general population of low- and middle-income countries. Since 2003, we have also seen LGV in high-income countries but exclusively in men who have sex with men. The number of patients with LGV has increased in the last decade, and the proportion in men who have sex with men without HIV has increased dramatically.

In low- and middle-income countries, LGV affects women and men and often causes genital complaints. In the men who have sex with men in the population in high-income countries, the vast majority of men suffer from anorectal infections that mimic chronic inflammatory bowel diseases like Crohn disease. LGV is not always directly recognized, because the presentations are often nonspecific and additional diagnostics are not distinctive. When sexually transmitted infections are not considered in the diagnostic work-up, consequent delay and inappropriate treatments can occur. In patients with anorectal complaints, a properly conducted sexual history followed by a sexually transmitted infection diagnostics is key to diagnose LGV. Early recognition and adequate antibiotic treatment can prevent complications and unnecessary additional diagnostic procedure, halting further transmission.

性病性淋巴肉芽肿（LGV）是一种严重的、侵袭性的、溃疡性的性传播感染（STI），由沙眼衣原体血清L1、L2和L3引起。直到2003年，我们在低收入和中等收入国家（LMIC）的一般人群中看到了地方政府感染。自2003年以来，我们在高收入国家（HIC）也看到了LGV，但仅限于男男性行为者（MSM）。在过去十年中，LGV患者的数量有所增加，而男同性恋者中未感染艾滋病毒的比例也急剧增加。在低收入和中等收入国家，LGV影响女性和男性，并经常引起生殖器疾病。在HIC的男同性恋人群中，绝大多数男性患有肛门直肠感染，类似于克罗恩病等慢性炎症性肠病。LGV并不总是能被直接识别，因为其表现通常是非特异性的，附加的诊断也不具有特异性。如果在诊断工作中没有考虑到性传播感染，可能会出现相应的延误和不适当的治疗。在肛肠疾患患者中，正确进行性行为史并进行性传播感染诊断是诊断LGV的关键。早期识别和适当的抗生素治疗可以预防并发症，产生不必要的额外诊断，并阻止进一步传播。

{"title":"Lymphogranuloma venereum, an invasive and destructive sexually transmitted infection with many faces","authors":"Henry J.C. de Vries MD, PhD","doi":"10.1016/j.clindermatol.2025.09.009","DOIUrl":"10.1016/j.clindermatol.2025.09.009","url":null,"abstract":"<div><div>Lymphogranuloma venereum (LGV) is a serious, invasive, ulcerative sexually transmitted infection caused by <em>Chlamydia trachomatis</em> serovar L1, L2, and L3. Until 2003, we saw LGV among the general population of low- and middle-income countries. Since 2003, we have also seen LGV in high-income countries but exclusively in men who have sex with men. The number of patients with LGV has increased in the last decade, and the proportion in men who have sex with men without HIV has increased dramatically.</div><div>In low- and middle-income countries, LGV affects women and men and often causes genital complaints. In the men who have sex with men in the population in high-income countries, the vast majority of men suffer from anorectal infections that mimic chronic inflammatory bowel diseases like Crohn disease. LGV is not always directly recognized, because the presentations are often nonspecific and additional diagnostics are not distinctive. When sexually transmitted infections are not considered in the diagnostic work-up, consequent delay and inappropriate treatments can occur. In patients with anorectal complaints, a properly conducted sexual history followed by a sexually transmitted infection diagnostics is key to diagnose LGV. Early recognition and adequate antibiotic treatment can prevent complications and unnecessary additional diagnostic procedure, halting further transmission.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"44 1","pages":"Pages 29-35"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human papillomavirus: An update HPV：最新进展。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2026-01-01 Epub Date: 2025-09-24 DOI: 10.1016/j.clindermatol.2025.09.012

Manik Kohli MB ChB, MSc, MRCP , Christopher B. Bunker MA, MD, FRCP , Georgios Kravvas BSc, MB BS, MRCP

Human papillomaviruses (HPV) comprise a group of DNA viruses with more than 450 types identified. HPV represents one of the most common viral infections globally. HPV can cause a wide spectrum of clinical disease depending on type, including benign lesions (cutaneous or anogenital warts), premalignant lesions (intraepithelial neoplasia), and anogenital cancers; however, infection may also frequently remain subclinical. Even though the role of HPV in the pathogenesis of penile, vulval, and anal intraepithelial neoplasia and other cutaneous diseases has been recognized, robust evidence for the role of screening and effective management is often lacking. The implementation of prophylactic vaccination for young people and at-risk adults in high-income countries has proven successful, and now there is growing interest in postexposure vaccination.

人乳头瘤病毒（HPV）是一组DNA病毒，已确定的类型超过450种。HPV是全球最常见的病毒感染之一。HPV可根据类型引起广泛的临床疾病，包括良性病变（皮肤或肛门生殖器疣），恶性前病变（上皮内瘤变）和肛门生殖器癌；然而，感染也可能经常是亚临床的。尽管HPV在阴茎、外阴和肛门上皮内瘤变和其他皮肤病的发病机制中的作用已经得到承认，但通常缺乏筛查和有效管理的有力证据。事实证明，在高收入国家对年轻人和高危成年人实施预防性疫苗接种是成功的，现在人们对接触后疫苗接种的兴趣越来越大。

引用次数: 0

Beyond the axilla: The evolving role of botulinum toxin in the treatment of facial, scalp, and focal hyperhidrosis. 超越腋窝：肉毒毒素在面部、头皮和局灶性多汗症治疗中的演变作用。

IF 2.2 4区医学 Q2 DERMATOLOGY

Clinics in dermatology

Pub Date : 2025-12-27 DOI: 10.1016/j.clindermatol.2025.12.003

Joe Farah, Elias Hanna, Saad Aad, Carl Karam, Antoine Ghanem

Botulinum toxin type A is an established treatment for focal hyperhidrosis of the axillae and palms, but its use has recently expanded to include craniofacial, facial, and scalp hyperhidrosis. This systematic review with narrative synthesis evaluates the clinical use of botulinum toxin type A for focal hyperhidrosis across multiple anatomic sites. A structured search of PubMed/MEDLINE, Embase, and Scopus was conducted for English-language human studies published between 2000 and 2025. Original clinical studies reporting outcomes related to sweat reduction, disease severity, quality of life, duration of effect, or adverse events were included, whereas reviews and non-original publications were used only for background and citation tracking. A total of 13 original clinical studies met the inclusion criteria. Evidence was strongest for axillary hyperhidrosis, with randomized controlled trials consistently demonstrating substantial reductions in sweating and sustained patient-reported benefits. Palmar hyperhidrosis showed reliable efficacy, although treatment was limited by injection discomfort and transient weakness. Evidence for craniofacial, facial, and scalp hyperhidrosis consisted primarily of small cohorts and case series that nevertheless reported meaningful symptom improvement and acceptable safety profiles, despite heterogeneity in dosing and injection techniques. Overall, botulinum toxin type A remains a cornerstone therapy for focal hyperhidrosis, and although evidence beyond the axillae is less robust, available data support its use in selected patients and underscore the need for larger, standardized studies of craniofacial and scalp hyperhidrosis.

A型肉毒杆菌毒素（BoNTA）是一种治疗腋窝和手掌局灶性多汗症的有效方法，但其用途最近已扩大到包括颅面、面部和头皮多汗症。本系统综述以叙述性综合评价BoNTA治疗多解剖部位局灶性多汗症的临床应用。对2000年至2025年间发表的英语人类研究进行了PubMed/MEDLINE、Embase和Scopus的结构化搜索。报告与减汗、疾病严重程度、生活质量、效果持续时间或不良事件相关的结果的原始临床研究被纳入，而综述和非原始出版物仅用于背景和引文跟踪。共有33项原始临床研究符合纳入标准。腋窝多汗症的证据最强，随机对照试验一致显示出汗显著减少和持续的患者报告的益处。手掌多汗症表现出可靠的疗效，尽管治疗受到注射不适和短暂虚弱的限制。颅面、面部和头皮多汗症的证据主要由小队列和病例系列组成，尽管剂量和注射技术存在异质性，但仍报告了有意义的症状改善和可接受的安全性概况。总的来说，BoNTA仍然是局灶性多汗症的基础疗法，虽然腋窝以外的证据不太有力，但现有数据支持其在选定患者中的应用，并强调需要对颅面和头皮多汗症进行更大规模、标准化的研究。

{"title":"Beyond the axilla: The evolving role of botulinum toxin in the treatment of facial, scalp, and focal hyperhidrosis.","authors":"Joe Farah, Elias Hanna, Saad Aad, Carl Karam, Antoine Ghanem","doi":"10.1016/j.clindermatol.2025.12.003","DOIUrl":"10.1016/j.clindermatol.2025.12.003","url":null,"abstract":"<p><p>Botulinum toxin type A is an established treatment for focal hyperhidrosis of the axillae and palms, but its use has recently expanded to include craniofacial, facial, and scalp hyperhidrosis. This systematic review with narrative synthesis evaluates the clinical use of botulinum toxin type A for focal hyperhidrosis across multiple anatomic sites. A structured search of PubMed/MEDLINE, Embase, and Scopus was conducted for English-language human studies published between 2000 and 2025. Original clinical studies reporting outcomes related to sweat reduction, disease severity, quality of life, duration of effect, or adverse events were included, whereas reviews and non-original publications were used only for background and citation tracking. A total of 13 original clinical studies met the inclusion criteria. Evidence was strongest for axillary hyperhidrosis, with randomized controlled trials consistently demonstrating substantial reductions in sweating and sustained patient-reported benefits. Palmar hyperhidrosis showed reliable efficacy, although treatment was limited by injection discomfort and transient weakness. Evidence for craniofacial, facial, and scalp hyperhidrosis consisted primarily of small cohorts and case series that nevertheless reported meaningful symptom improvement and acceptable safety profiles, despite heterogeneity in dosing and injection techniques. Overall, botulinum toxin type A remains a cornerstone therapy for focal hyperhidrosis, and although evidence beyond the axillae is less robust, available data support its use in selected patients and underscore the need for larger, standardized studies of craniofacial and scalp hyperhidrosis.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145854740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

首页上一页

下一页尾页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Clinics in dermatology

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀