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Hand rejuvenation with dermal fillers: Key aspects and a comparison of commonly used fillers. 手部年轻化与真皮填充物:关键方面和常用填充物的比较。
IF 2.2 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-12-07 DOI: 10.1016/j.clindermatol.2025.12.001
Laila Hassan, Alexander Rivkin, Eleni Kroumpouzos, Asma Qaiser Qureshi, George Kroumpouzos

There has been an increasing demand for hand rejuvenation procedures. Hand evaluation is critical before any such procedure, and recently proposed five-point scales, including the Merz Hand Grading Scale and Allergan Hand Volume Deficit Scale, provide an objective assessment of volume loss of soft tissues. Dermal fillers, including hyaluronic acid (HA), calcium hydroxylapatite (CaHA), and poly-L-lactic acid, can address volume loss, contour irregularities, and texture changes associated with aging. Our literature review includes 12 studies with HA, seven with CaHA, and two with poly-L-lactic acid fillers. One study used a hybrid HA-CaHA filler. The superficial lamina contains minimal vascular or neural structures, making it the safest plane for filler placement. Techniques such as proximal-to-distal fanning allow smooth and homogeneous filler placement with minimal trauma. A blunt cannula is often preferred to minimize vascular injury. All fillers discussed here-HA, CaHA, and poly-L-lactic acid-have a good safety profile and provide acceptable aesthetic outcomes associated with high patient satisfaction. HA fillers provide instant volume restoration and hydration, whereas CaHA and poly-L-lactic acid are advantageous for improving texture and skin quality. Patient counseling on available options and selecting the most suitable filler that aligns with patient expectations are crucial to achieving successful outcomes.

对手部年轻化手术的需求不断增加。在任何此类手术之前,手部评估是至关重要的,最近提出的5分制量表,包括Merz手部分级量表(MHGS)和Allergan手部体积缺陷量表,提供了对软组织体积损失的客观评估。真皮填充物,包括透明质酸(HA)、羟基磷灰石钙(CaHA)和聚l -乳酸(PLLA),可以解决与衰老相关的体积损失、轮廓不规则和质地变化。我们的文献综述包括12项HA填充物研究,7项CaHA填充物研究和2项PLLA填充物研究。一项研究使用了混合HA-CaHA填充剂。浅层含有极少的血管或神经结构,是放置填充物最安全的平面。诸如近端到远端扇形等技术可以使填充物放置平滑均匀,创伤最小。通常首选钝管,以尽量减少血管损伤。这里讨论的所有填充物-ha、CaHA和pla -都具有良好的安全性,并提供可接受的美学结果,患者满意度高。透明质酸填充剂提供即时的体积修复和水合作用,而CaHA和PLLA有利于改善质地和皮肤质量。患者咨询可用的选择和选择最合适的填充物,符合患者的期望是取得成功的结果至关重要。
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引用次数: 0
Self-made journals in dermatology: Navigating the ethical landscape of dermatologist-sponsored independent journals. 皮肤病学自制期刊:皮肤科医生赞助的独立期刊的伦理景观导航。
IF 2.2 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-11-24 DOI: 10.1016/j.clindermatol.2025.11.003
Julia Ross, Camilla M Lee, Timothy Klufas, Albert E Zhou, Jane M Grant-Kels

Dissemination of research findings is a crucial part of academic progress; however, many barriers to publishing in dermatology may prevent equitable researcher involvement and representation. The term "independent journal" (IJ) is not yet widely established in the academic literature. IJs refer to self-initiated and potentially self-sponsored journals. IJs are typically initiated by individual clinicians or small groups rather than well-established organizations or commercial entities and have the goal of disseminating new research ideas or filling a current gap in the literature. Although many IJs in dermatology have gained respect and contribute meaningfully to the field, there are ethical concerns regarding potential founding-sponsorship bias, peer-review protocols, and the resources used to ensure academic quality. To avoid potential ethical concerns regarding IJs' credibility, the goals of the journal and the peer-review processes should be clearly delineated. IJs offer the opportunity to make research more accessible and transform the publishing industry. Herein, we define and delineate IJs from other journals, while exploring ethical issues and directions for clinicians to consider when studying or creating journals.

研究成果的传播是学术进步的重要组成部分;然而,许多障碍发表在皮肤病学可能会阻止公平的研究人员参与和代表性。独立期刊(Independent Journal, IJ)一词在学术文献中尚未广泛确立。ij指的是自主创办和潜在的自费期刊。ij通常由临床医生个人或小团体发起,而不是成熟的组织或商业实体,其目标是传播新的研究思想或填补当前文献中的空白。虽然许多皮肤病学的ij已经获得了尊重,并为该领域做出了有意义的贡献,但在潜在的创始赞助偏见、同行评审协议和用于确保学术质量的资源方面存在伦理问题。为了避免潜在的关于ij可信度的伦理问题,期刊和同行评议过程的目标应该清楚地描述。ij有机会使研究更容易获得,并代表着改变出版业的机会。在此,我们定义和描述来自其他期刊的ij,同时探索临床医生在研究或创建期刊时需要考虑的伦理问题和方向。
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引用次数: 0
From Salves to Sulzberger: The emergence of the American approach to acne treatment. 从药膏到苏兹伯格:美国痤疮治疗方法的出现。
IF 2.2 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-11-13 DOI: 10.1016/j.clindermatol.2025.11.001
Julia Woźna, Wiktoria Woźna, Ewa Mojs, Andrzej Grzybowski, Ryszard Żaba

Acne vulgaris is the most prevalent chronic skin disorder in the United States, affecting approximately 50 million individuals annually. Despite the availability of effective modern therapies, the evolution of acne treatment remains a rich and understudied topic in dermatologic history. This review traces the historic progression of acne management in the United States, highlighting key therapeutic milestones, shifts in clinical practice, and evolving societal perceptions of the disease. Early approaches to acne worldwide, rooted in humoral theory, included arsenicals, bloodletting, sulfur preparations, and folk remedies. The late 19th and early 20th centuries saw a gradual move toward rational therapies, including dietary regulation, topical antiseptics, and even vaccine and x-ray treatments. By the mid-20th century, dermatology entered a scientific era led by figures such as Dr Marion B. Sulzberger, ushering in antibiotic therapy, keratolytics, and eventually isotretinoin, representing the first treatment to target all major pathogenic factors. This period also marked a cultural shift: acne was no longer seen as a trivial esthetic issue but a condition with significant psychologic implications. The history of acne therapy in the United States illustrates a transition from empiric and often harmful interventions toward evidence-based, patient-centered care. Although treatments have advanced significantly, enduring challenges remain, particularly in addressing the psychologic burden of the disease. Continued innovation, both pharmacologic and psychosocial, is essential to meet the complex needs of acne patients today.

寻常痤疮是美国最常见的慢性皮肤病,每年影响约5000万人。尽管有有效的现代治疗方法,痤疮治疗的演变仍然是皮肤病学历史上一个丰富而未充分研究的话题。本综述旨在追溯美国痤疮治疗的历史进展,强调关键的治疗里程碑,临床实践的转变,以及不断发展的社会对该疾病的看法。世界范围内治疗痤疮的早期方法,植根于体液理论,包括砒霜、放血、硫磺制剂和民间疗法。19世纪末和20世纪初,人们逐渐转向理性治疗,包括饮食调节、局部防腐剂,甚至疫苗和x射线治疗。到20世纪中期,皮肤病学进入了一个由马里昂·b·苏兹伯格博士等人物领导的科学时代,迎来了抗生素治疗、角化治疗和最终的异维甲酸,这是第一个针对所有主要致病因素的治疗方法。这一时期也标志着文化的转变:痤疮不再被视为微不足道的审美问题,而是一种具有重大心理影响的疾病。痤疮治疗在美国的历史表明,从经验和往往有害的干预过渡到循证,以病人为中心的护理。虽然治疗取得了重大进展,但仍然存在持久的挑战,特别是在解决该疾病的心理负担方面。持续创新,药理学和心理社会,是必不可少的,以满足痤疮患者的复杂需求今天。
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引用次数: 0
Anatolian contribution to surgery and medicine in the 15th century - Şerefeddin Sabuncuoğlu. 15世纪安纳托利亚对外科和医学的贡献- Şerefeddin Sabuncuoğlu。
IF 2.2 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-11-11 DOI: 10.1016/j.clindermatol.2025.11.002
Uwe Wollina, Ayşe Serap Karadağ

Şerefeddin Sabuncuoğlu (1385 to 1468 or 1470), a physician and surgeon from Amasya in Anatolia, is the author of three major books on pharmacy, medicine, and surgery, as well as the author of the first illustrated surgical textbook in the Turkish-Islamic literature, Cerrahiyyet'ul-Haniyye (Imperial Surgery), written in Turkish. It is the first book to contain colored illustrations of surgical procedures and instruments. Sabuncuoğlu was an unpretentious, curious, and intelligent physician and surgeon, a calligrapher, and a miniature artist. Although the teachers of medicine and the surgeons in Central Anatolia used his book, it was ignored by the Ottoman scientific elite in Istanbul during his lifetime.

Şerefeddin Sabuncuoğlu(1385年至1468年或1470年),来自安纳托利亚阿马西亚的内科医生和外科医生,著有三本关于药剂学、医学和外科的主要著作,也是土耳其-伊斯兰文学Cerrahiyyet'ul-Haniyye(帝国外科)中第一本带插图的外科教科书的作者,该书用土耳其语写成。这是第一本包含外科手术过程和仪器的彩色插图的书。Sabuncuoğlu是一位谦逊、好奇、聪明的内科医生、外科医生、书法家和微型艺术家。尽管安纳托利亚中部的医学教师和外科医生使用过他的书,但在他有生之年,伊斯坦布尔的奥斯曼科学精英却对他的书视而不见。
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引用次数: 0
Reproductive ethics: Defining the dermatologist's role. 生殖伦理:定义皮肤科医生的角色。
IF 2.2 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-11-04 DOI: 10.1016/j.clindermatol.2025.10.014
Samantha Strelzer, Timothy Klufas, Julie Frances Solimine, Albert E Zhou, Jane M Grant-Kels

Dermatologists routinely care for women with childbearing potential and pregnant women. When the mother or their fetus has a dermatologic disease, the dermatologist is often involved in helping potential parents navigate the complex medical and ethical decisions that are required. Dermatologists also regularly advise patients of childbearing age who require teratogenic medications such as isotretinoin on how to navigate its use safely. As features of some life-threatening dermatologic skin diseases can be identified prenatally and genetic testing enables confirmatory diagnosis before birth, dermatologists should be prepared to ethically support parents considering the options of preparing to care for their child with a devastating skin disease or terminating the pregnancy. Dermatologists also have an ethical obligation to educate their pregnant patient regarding the risks associated with genetically inherited conditions and the potential therapeutic options and prognosis. In view of the recent change in the legal landscape regarding abortion, dermatologists now need to be aware of local ordinance and how to refer to providers knowledgeable on the topic to best support a patient in their pregnancy.

皮肤科医生经常护理有生育能力的妇女和孕妇。当母亲或胎儿患有皮肤病时,皮肤科医生通常会帮助潜在的父母做出复杂的医疗和伦理决定。皮肤科医生也经常建议需要异维甲酸等致畸药物的育龄患者如何安全使用。由于一些危及生命的皮肤病的特征可以在产前识别,基因检测可以在出生前进行确诊,皮肤科医生应该准备好在道德上支持父母考虑准备照顾患有毁灭性皮肤病的孩子或终止妊娠的选择。皮肤科医生也有道德义务教育他们的孕妇有关遗传疾病的风险和潜在的治疗选择,以及预后。鉴于最近关于堕胎的法律环境发生了变化,皮肤科医生现在需要了解当地法规,以及如何参考在该主题方面知识渊博的提供者,以最好地支持患者的怀孕。
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引用次数: 0
DO and MD enrollment in US dermatology residencies after the graduate medical education merger: Implications for access. 研究生医学教育合并后美国皮肤科住院医师注册DO和MD:对准入的影响。
IF 2.2 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-11-02 DOI: 10.1016/j.clindermatol.2025.10.013
Lily Park, Sarah Beach, Brad P Glick, Anthony V Benedetto
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引用次数: 0
Primary cutaneous mucinoses in connective tissue diseases as a diagnostic and prognostic challenge 结缔组织疾病的原发性皮肤粘液病作为诊断和预后的挑战。
IF 2.2 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.09.028
Giorgio Stabile MD , Nazario Pesce MD , Giorgia Di Marco MD , Antonio Podo Brunetti MD , Gianmarco Diego Bigotto MD , Stefania Guida MD , Franco Rongioletti MD
Mucin deposition in the skin, a hallmark feature in dermatopathology, is frequently associated with connective tissue diseases such as lupus erythematosus, dermatomyositis, and, to a lesser extent, scleroderma. Although mucin deposition commonly accompanies specific skin lesions in lupus erythematosus, dermatomyositis, and sometimes scleroderma, its occurrence as a distinct clinical manifestation with defining histopathologic features is rare. Such presentations that are classified as primary cutaneous mucinoses not only aid in diagnosis but may also have prognostic implications. This study systematically reviews the literature to evaluate case demographics, clinical characteristics, histologic findings, immunologic markers, and treatment responses of primary cutaneous mucinoses linked to connective tissue diseases. Our findings highlight that mucin deposition exhibits variable presentations and serves as a valuable diagnostic clue, particularly when integrated with other clinical and histopathologic criteria.
Mucin, a high-molecular-weight glycoprotein complex primarily composed of hyaluronic acid, is a standard component of dermal connective tissues. It is produced in small amounts by fibroblasts and mast cells and is known for its high water-holding capacity. Excessive mucin deposition, however, which can occur in certain pathologic states, leads to dermal swelling known as myxedema. Cutaneous mucinosis is often associated with connective tissue diseases, in which mucin deposition can serve as histologic evidence for conditions such as lupus erythematosus (LE) or dermatomyositis (DM), particularly in the appropriate clinical context. Less frequently, mucin is also observed in scleroderma cases.1,2 Although mucin deposition can accompany specific skin lesions in LE and DM, cases in which it is a prominent and defining histopathologic feature are rare. Such cases classified into the chapter of primary cutaneous mucinoses have diagnostic value and may also serve as prognostic indicators. This review assesses the diagnostic and prognostic significance of primary cutaneous mucinoses associated with connective tissue diseases.
皮肤中的粘蛋白沉积是皮肤病理学的一个标志性特征,通常与结缔组织疾病如红斑狼疮(LE)、皮肌炎(DM)以及在较小程度上与硬皮病有关。尽管粘蛋白沉积通常伴随着LE、DM和硬皮病的特定皮肤病变,但其作为明确的组织病理学特征的独特临床表现是罕见的。这些被归类为原发性皮肤粘液病的表现不仅有助于诊断,而且可能具有预后意义。本研究系统地回顾文献,以评估与结缔组织疾病相关的原发性皮肤粘液病的病例人口统计学、临床特征、组织学表现、免疫标志物和治疗反应。我们的研究结果强调粘蛋白沉积表现出不同的表现,并作为一种有价值的诊断线索,特别是当与其他临床和组织病理学标准相结合时。
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引用次数: 0
Tadeusz Stępniewski: Polish dermatologist and “Righteous Among the Nations” Tadeusz stepeniewski:波兰皮肤科医生和“正义的国家”。
IF 2.2 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.09.023
Sophie Walter BMed, MD, BSc(Med) (Hons)
This presentation presents the life and career of Tadeusz Stępniewski (1905-1987), a Polish dermatologist awarded the title “Righteous Among the Nations” for his bravery saving Jews during the Holocaust, collates information about other dermatologists who have also received the title and reflects on the place of virtue in the profession. Various sources were used to provide information about Stępniewski, including copies of materials held by the Archives Department of Yad Vashem, Israel’s Holocaust memorial authority. At the outbreak of World War II, Stępniewski had a private dermatology practice in central Warsaw and was affiliated with the Skin and Venereal Diseases Clinic at the University of Warsaw. During the German occupation, he assisted Jews by helping them escape from the Warsaw ghetto, hiding them in various locations, providing dermatologic care and other medical treatments, contributing to an underground medical publication, and giving financial aid. Stępniewski is one of seven dermatologists who have received the Righteous Among the Nations title. Their heroic deeds bring to the forefront the role of virtue in all aspects of the lives of dermatologists and other medical professionals.
Tadeusz Stepniewski(1905-1987)是一位波兰皮肤科医生,因其在大屠杀期间拯救犹太人的英勇行为而被授予“国际正义”称号,他的生活和职业生涯整理了其他获得该称号的皮肤科医生的信息,并反思了美德在该职业中的地位。提供关于斯特普涅夫斯基的信息使用了各种来源,包括以色列大屠杀纪念机构亚德瓦谢姆档案馆持有的材料副本。第二次世界大战爆发时,斯特普涅夫斯基在华沙市中心开了一家私人皮肤科诊所,隶属于华沙大学的皮肤和性病诊所。在德国占领期间,他帮助犹太人逃离华沙隔都,把他们藏在不同的地方,提供皮肤护理和其他医疗服务,为地下医学出版物撰稿,并提供经济援助。斯蒂芬尼夫斯基是七位获得“国际正义”称号的皮肤科医生之一。他们的英雄事迹使美德在皮肤科医生和其他医疗专业人员生活的各个方面发挥了重要作用。
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引用次数: 0
Early history of gender reassignment surgery in Prussia and Saxony 普鲁士和萨克森性别重置手术的早期历史。
IF 2.2 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.07.008
Uwe Wollina MD , Leonard J. Hoenig MD , Lawrence Charles Parish MD, MD (Hon), FRCP (Edin)
This contribution provides a note on the early days of gender reassignment surgery, which was pioneered by Felix Abraham, Erwin Gohrbrandt, Ludwig Levy-Lenz, and Kurt Warnekros need dates during the 1920s. Their experimental surgeries would gain significant attention through the mass media. Such reassignment surgery has been illustrated by the life and death of Danish painter Einar Wegener (1882-1931), who underwent several gender reassignment surgeries. The narratives of his life are discussed with the views of medical progress made from the early 20th century until now.
这篇文章提供了一份关于性别重置手术早期的笔记,这项手术是由费利克斯·亚伯拉罕、欧文·高布兰特、路德维希·莱维-伦茨和库尔特·沃内克罗斯在20世纪20年代首创的。他们的实验性手术通过大众媒体获得了极大的关注。丹麦画家艾纳·韦格纳(Einar Wegener, 1882-1931)接受了多次性别重新分配手术,他的生与死就说明了这种重新分配手术。从20世纪初到现在,他的生活叙述与医学进步的观点进行了讨论。
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引用次数: 0
Rethinking research metrics in dermatology and beyond 重新思考皮肤病学及其他领域的研究指标。
IF 2.2 4区 医学 Q2 DERMATOLOGY Pub Date : 2025-11-01 DOI: 10.1016/j.clindermatol.2025.08.002
Waseem Hassan PhD , Fred Paas PhD
Assessing academic performance in dermatology is an interesting and evolving challenge. Early-career researchers often look for clear indicators to identify leading authors; however, reliance on single measures such as citation counts or the h-index provides only a limited view of scholarly influence. Using diverse bibliometric indicators from Scopus, we observed that author rankings shifted considerably depending on the metric applied, reflecting the lack of agreement on how best to capture academic impact. Similarly, we noted that ethical publications (letters, notes, and related formats) in dermatology may contribute to scholarly discussions and institutional practices but often receive modest citation profiles, highlighting the gap between measurable indicators and genuine value. Inflated authorship practices and citation manipulation further complicate fair evaluation. Fractional authorship models and multidimensional frameworks that consider publication type, journal quality, collaboration, funding strength, and broader societal contributions may offer more balanced perspectives. We suggest that institutions, journals, and training programs promote the ethical use of metrics and integrate qualitative assessments alongside quantitative ones. Such an approach can foster fairness, transparency, and meaningful recognition within dermatology and academic medicine more broadly.
评估皮肤科的学术表现是一个有趣的和不断发展的挑战。早期职业研究人员经常寻找明确的指标来确定主要作者;然而,对引用数或h指数等单一指标的依赖只能提供有限的学术影响观点。通过使用来自Scopus的各种文献计量指标,我们观察到作者排名根据所采用的度量标准发生了很大的变化,这反映了在如何最好地捕捉学术影响方面缺乏共识。同样,我们注意到,皮肤病学的伦理出版物(信件、笔记和相关格式)可能有助于学术讨论和机构实践,但往往得到适度的引用,突出了可测量指标与真正价值之间的差距。夸大作者身份和引文操纵进一步使公平评价复杂化。部分作者模型和多维框架——考虑出版类型、期刊质量、合作、资金实力和更广泛的社会贡献——可能提供更平衡的观点。我们建议机构、期刊和培训项目促进指标的道德使用,并将定性评估与定量评估结合起来。这种方法可以促进皮肤病学和学术医学更广泛的公平、透明和有意义的认可。
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引用次数: 0
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Clinics in dermatology
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