Clinics in dermatology最新文献

Physicians and surgeons have a threefold increased risk of glioblastoma compared with population controls. We discuss the potential role of dermatology neurotoxin and carcinogenic occupational exposure, particularly to formalin/formaldehyde; how to reduce those exposures; and the ethical imperative for dermatologists to protect themselves, their staff, and their patients.

Derived from the survival advantage needed to eradicate harmful irritants from the skin's surface, itch, also known as pruritus, is an intriguing phenomenon and a key feature of many dermatologic diseases. The pathologic form, chronic itch, is a condition that precedes itself by its complex pathophysiology, numerous etiologies, and interplay of mechanisms that often make it difficult to diagnose and treat. One particular sufferer of this condition, the 18th-century French emperor Napoleon Bonaparte, makes for a compelling case study of the complexity of chronic itch. We delve into the many etiologies and mechanisms of chronic itch, using Napoleon's lifelong struggle with this condition as our model, identifying potential environmental, neurologic, psychiatric, and immunologic origins of his condition.

Tiber Island in Rome has a rich history as a center of worship and health care. Its origins date back to ancient times, with the establishment of the Temple of Asclepius marking its role in healing practices. Over centuries, it evolved into a hub for medical innovation and refuge during epidemics and conflicts. During World War II, Fatebenefratelli Hospital on Tiber Island played a pivotal role in sheltering Jews from Nazi persecution. Using a fictitious disease termed "K syndrome," doctors helped endangered Jewish patients evade capture and deportation to concentration camps by exploiting Nazi fears of contagion. Patients diagnosed with "K syndrome" were shielded from apprehension, highlighting the hospital's innovative tactics to save lives amidst wartime atrocities. This episode underscores the hospital's courageous efforts and enduring legacy as a beacon of compassion in the face of adversity.

Patient demand for procedures has increased in the evolving landscape of cosmetic dermatology. This has been fueled, in part, by social media and the growing normalization of cosmetic enhancements, developments that have led some patients to have potentially unrealistic expectations and place undue pressure on dermatologists to meet these often unrealistic demands. This pressure is exacerbated further by patients who are seen as difficult, demanding, and time-consuming and who may require extensive counseling. Physicians may adopt dynamic or differential pricing strategies to offset the additional time and effort that these patients require. We discuss the ethical concerns surrounding these pricing strategies in the cosmetic sphere, highlight the importance of transparency in pricing, and offer suggestions to promote clarity and fairness in cosmetic dermatology practices.

Bibliometric methods were used to analyze publications on the use of artificial intelligence (AI) in skin cancer from 2010 to 2022, aiming to explore current publication trends and future directions. A comprehensive search using four terms, "artificial intelligence," "machine learning," "deep learning," and "skin cancer," was performed in the Web of Science database for original English language publications on AI in skin cancer from 2010 to 2022. We visually analyzed publication, citation, and coupling information, focusing on authors, countries and regions, publishing journals, institutions, and core keywords. The analysis of 989 publications revealed a consistent year-on-year increase in publications from 2010 to 2022 (0.51% versus 33.57%). The United States, India, and China emerged as the leading contributors. IEEE Access was identified as the most prolific journal in this area. Key journals and influential authors were highlighted. Examination of the top 10 most cited publications highlights the significant potential of AI in oncology. Co-citation network analysis identified four primary categories of classical literature on AI in skin tumors. Keyword analysis indicated that "melanoma," "classification," and "deep learning" were the most prevalent keywords, suggesting that deep learning for melanoma diagnosis and grading is the current research focus. The term "pigmented skin lesions" showed the strongest burst and longest duration, whereas "texture" was the latest emerging keyword. AI represents a rapidly growing area of research in skin cancer with the potential to significantly improve skin cancer management. Future research will likely focus on machine learning and deep learning technologies for screening and diagnostic purposes.

Frontal fibrosing alopecia (FFA) is characterized by a receding hairline in the frontotemporal region due to the gradual loss of hair follicles and then follicular stem cells and follicular fibrosis. Follicular stem cells are crucial in skin healing after chemical peeling and other resurfacing procedures. Although there is a possible association of FFA with a history of facial and scalp surgical procedures, there is no information on the safety of cosmetic procedures in patients with FFA. We report five patients with FFA who experienced unusual and complicated outcomes after undergoing a deep chemical peel (phenol and croton oil). As the prevalence of FFA continues to increase globally, it is essential to raise awareness about the potential incompatibility of this dermatologic disorder with specific cosmetic procedures, such as deeper peels and other resurfacing modalities.