Clinical nutrition最新文献

{"title":"Enhancing colorectal cancer survivorship: Integrating social work to optimize Dietary and lifestyle interventions","authors":"Yi Qiao, Fulin Guo, Pan Liu","doi":"10.1016/j.clnu.2024.09.043","DOIUrl":"10.1016/j.clnu.2024.09.043","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 11","pages":"Pages 108-109"},"PeriodicalIF":6.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142364711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health perspectives: The benefits of low-inflammatory diet and lifestyle","authors":"Qingyun Li, Yanan Duan","doi":"10.1016/j.clnu.2024.09.042","DOIUrl":"10.1016/j.clnu.2024.09.042","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 11","pages":"Pages 154-155"},"PeriodicalIF":6.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-term intermittent fasting and energy restriction do not impair rates of muscle protein synthesis: A randomised, controlled dietary intervention","authors":"Imre W.K. Kouw ,&nbsp;Evelyn B. Parr ,&nbsp;Michael J. Wheeler ,&nbsp;Bridget E. Radford ,&nbsp;Rebecca C. Hall ,&nbsp;Joan M. Senden ,&nbsp;Joy P.B. Goessens ,&nbsp;Luc J.C. van Loon ,&nbsp;John A. Hawley","doi":"10.1016/j.clnu.2024.09.034","DOIUrl":"10.1016/j.clnu.2024.09.034","url":null,"abstract":"<div><h3>Background</h3><div>Intermittent fasting (IF) is an effective energy restricted dietary strategy to reduce body and fat mass and improve metabolic health in individuals with either an overweight or obese status. However, dietary energy restriction may impair muscle protein synthesis (MPS) resulting in a concomitant decline in lean body mass. Due to periods of prolonged fasting combined with irregular meal intake, we hypothesised that IF would reduce rates of MPS compared to an energy balanced diet with regular meal patterns.</div></div><div><h3>Aims</h3><div>We assessed the impact of a short-term, ten days, alternate day fasting or a continuous energy restricted diet to a control diet on integrated rates of skeletal MPS in middle-aged males with overweight or obesity.</div></div><div><h3>Methods</h3><div>Twenty-seven middle-aged males with overweight or obesity (age: 44.6 ± 5.4 y; BMI: 30.3 ± 2.6 kg/m²) consumed a three-day lead-in diet, followed by a ten-day controlled dietary intervention matched for protein intake, as alternate day fasting (ADF: 62.5 energy (En)%, days of 25 En% alternated with days of 100 En% food ingestion), continuous energy restriction (CER: 62.5 En%), or an energy balanced, control diet (CON: 100 En%). Deuterated water (D₂O) methodology with saliva, blood, and skeletal muscle sampling were used to assess integrated rates of MPS over the ten-day intervention period. Secondary measures included fasting plasma glucose, insulin, and gastrointestinal hormone concentrations, continuous glucose monitoring, and assessment of body composition.</div></div><div><h3>Results</h3><div>There were no differences in daily rates of MPS between groups (ADF: 1.18 ± 0.13, CER: 1.13 ± 0.16, and CON: 1.18 ± 0.18 %/day, <em>P</em> &gt; 0.05). The reductions in body mass were greater in ADF and CER compared to CON (<em>P</em> &lt; 0.001). Lean and fat mass were decreased by a similar magnitude across groups (main time effect, <em>P</em> &lt; 0.001; main group effect, <em>P</em> &gt; 0.05). Fasting plasma leptin concentrations decreased in ADF and CER (<em>P</em> &lt; 0.001), with no differences in fasting plasma glucose or insulin concentrations between groups.</div></div><div><h3>Conclusion</h3><div>Short-term alternate day fasting does not lower rates of MPS compared to continuous energy restriction or an energy balanced, control diet with matched protein intake. The prolonged effects of IF and periods of irregular energy and protein intake patterns on muscle mass maintenance remain to be investigated. This trial was registered under Australian New Zealand Clinical Trial Registry (<span><span>https://www.anzctr.org.au</span><svg><path></path></svg></span>), identifier no. ACTRN12619000757112.</div></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 11","pages":"Pages 174-184"},"PeriodicalIF":6.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply - Letter to the Editor","authors":"Hyunju Kim,&nbsp;Casey M. Rebholz","doi":"10.1016/j.clnu.2024.09.041","DOIUrl":"10.1016/j.clnu.2024.09.041","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 11","pages":"Pages 133-134"},"PeriodicalIF":6.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142375234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measurement of resting energy expenditure and its accuracy in women with breast cancer","authors":"Iolanda Cioffi ,&nbsp;Olivia Di Vincenzo ,&nbsp;Delia Morlino ,&nbsp;Bruna Ramos da Silva ,&nbsp;Carla M. Prado ,&nbsp;Lidia Santarpia ,&nbsp;Luca Scalfi ,&nbsp;Mario Giuliano ,&nbsp;Carmine De Angelis ,&nbsp;Fabrizio Pasanisi ,&nbsp;Grazia Arpino ,&nbsp;Maurizio Marra","doi":"10.1016/j.clnu.2024.09.037","DOIUrl":"10.1016/j.clnu.2024.09.037","url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>Breast cancer (BC) is frequently linked with obesity, metabolic syndrome, and sarcopenia. Therefore, measuring or accurately estimating resting energy expenditure (REE) is crucial for tailoring nutritional needs, managing weight and prevent under- or over-nutrition. We aimed to measure and compare REE between women with BC and a matched control group. Moreover, the prediction accuracy of selected formulas was evaluated.</div></div><div><h3>Methods</h3><div>Women aged ≥18 years with newly diagnosis of BC (stage 0-III) and body mass index (BMI) ≤ 30 kg/m² were included in this cross-sectional analysis. Anthropometry, indirect calorimetry, and bioelectrical impedance analysis (BIA) were performed. Patients with BC data were compared to healthy women with similar age and BMI range. Measured REE (mREE) was compared against 15 predictive equations. Agreement between methods was evaluated using Bland-Altman analysis.</div></div><div><h3>Results</h3><div>We included 106 women with BC (age 49.9 ± 11.1 years and BMI 24.5 ± 2.8 kg/m²) and 75 women as control group. There were no differences in age, anthropometry, and BIA variables between groups, except for percentage fat mass. Measured REE values, alone and adjusted for fat-free mass (FFM) and age, were higher in patients with BC compared to controls (+4.3 % and +6.1 %, respectively). Regarding REE prediction, most of the selected equations underestimated mREE. Precision varied widely, with the two Marra equations showing the highest agreement (73 % and 74.5 %) along with the Müller equation (74 %), however, the wide limit of agreement range indicates substantial variability.</div></div><div><h3>Conclusions</h3><div>Women with early-stage BC exhibited higher mREE compared to controls, albeit its clinical significance is unknown. None of the selected predictive equations provided accurate and precise REE estimates in this group. Although the Marra equation displayed the highest agreement, further studies are needed to evaluate REE variability and its prediction in women with BC.</div></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 11","pages":"Pages 54-64"},"PeriodicalIF":6.6,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of a whole foods dietary intervention on gastrointestinal symptoms, inflammation, and fecal microbiota in pediatric patients with cystic fibrosis: A pilot study","authors":"Nicole Green ,&nbsp;Carson Miller ,&nbsp;David Suskind ,&nbsp;Marshall Brown ,&nbsp;Christopher Pope ,&nbsp;Hillary Hayden ,&nbsp;Sharon McNamara ,&nbsp;Anna Kanter ,&nbsp;Laura Nay ,&nbsp;Lucas Hoffman ,&nbsp;Margaret Rosenfeld","doi":"10.1016/j.clnu.2024.09.036","DOIUrl":"10.1016/j.clnu.2024.09.036","url":null,"abstract":"<div><h3>Background</h3><div>Gastrointestinal (GI) complications are a significant source of morbidity for people with cystic fibrosis (PwCF). Historically, dietary recommendations in CF have focused on calories, typically emphasizing a high fat diet. The changing landscape of CF highlights the need to update this nutritional strategy. There is little research into how the quality of calories consumed by PwCF influences nutritional outcomes, GI symptoms, or likely contributors: intestinal inflammation and GI microbiology. We assessed the feasibility of a whole foods-based diet (WFD) and avoidance of ultra-processed foods, measuring safety/tolerability, adherence, and GI symptoms, as well as fecal measures of inflammation and microbiota among children with CF (CwCF) with GI symptoms.</div></div><div><h3>Methods</h3><div>Single center, 4-week dietary intervention involving CwCF aged 5–14 years who screened positive on GI symptom questionnaire. Assessments included weight, symptom questionnaires and adverse events (AEs). Stool was analyzed for microbiota (16S rRNA) and calprotectin.</div></div><div><h3>Results</h3><div>108 children were pre-screened, 9 enrolled and 8 initiated and completed the study. There were no significant changes in weight and no AEs. PEDS-QL GI identified overall improvement in symptoms. Certain symptom domains (constipation, diarrhea, gas/bloating, stomach pain and hurt) demonstrated significant improvement on the WFD. Of two participants with abnormal fecal calprotectin at enrollment, both exhibited decreased values on WFD. There was no significant change in microbiota diversity.</div></div><div><h3>Conclusion</h3><div>A WFD diet was feasible and safe in CwCF. There was improvement in GI symptom scores based on both parent and child assessments. Larger studies are needed to further investigate effects on intestinal inflammation and microbiota.</div></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 11","pages":"Pages 156-163"},"PeriodicalIF":6.6,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply - Letter to the editor entitled “Oral health perspectives: The benefits of low-inflammatory diet and lifestyle”","authors":"Evertine Wesselink,&nbsp;Hendriek C. Boshuizen,&nbsp;Anne-Sophie van Lanen,&nbsp;Dieuwertje E. Kok,&nbsp;Jeroen W.G. Derksen,&nbsp;Karel C. Smit,&nbsp;Johannes H.W. de Wilt,&nbsp;Miriam Koopman,&nbsp;Anne M. May,&nbsp;Ellen Kampman,&nbsp;Fränzel J.B. van Duijnhoven","doi":"10.1016/j.clnu.2024.09.039","DOIUrl":"10.1016/j.clnu.2024.09.039","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 11","pages":"Pages 65-66"},"PeriodicalIF":6.6,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply - Letter to editor entitled “Enhancing colorectal cancer survivorship: Integrating social work to optimize Dietary and lifestyle interventions”","authors":"Evertine Wesselink,&nbsp;Hendriek C. Boshuizen,&nbsp;Anne-Sophie van Lanen,&nbsp;Dieuwertje E. Kok,&nbsp;Jeroen W.G. Derksen,&nbsp;Karel C. Smit,&nbsp;Johannes H.W. de Wilt,&nbsp;Miriam Koopman,&nbsp;Anne M. May,&nbsp;Ellen Kampman,&nbsp;Fränzel J.B. van Duijnhoven","doi":"10.1016/j.clnu.2024.09.038","DOIUrl":"10.1016/j.clnu.2024.09.038","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 11","pages":"Pages 67-68"},"PeriodicalIF":6.6,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of active vitamin D supplementation on body weight and composition: A meta-analysis of individual participant data","authors":"Sabrina M. Oussaada ,&nbsp;Isis Akkermans ,&nbsp;Sandeep Chohan ,&nbsp;Jacqueline Limpens ,&nbsp;Jos W.R. Twisk ,&nbsp;Christiane Winkler ,&nbsp;Janaka Karalliedde ,&nbsp;J. Christopher Gallagher ,&nbsp;Johannes A. Romijn ,&nbsp;Mireille J. Serlie ,&nbsp;Kasper W. ter Horst","doi":"10.1016/j.clnu.2024.08.031","DOIUrl":"10.1016/j.clnu.2024.08.031","url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>Obesity is associated with vitamin D (VitD) deficiency. However, previous studies showed mixed effects of VitD (25-hydroxyVitD/calcidiol) supplementation on body weight. The biological actions of VitD require the hydroxylation of inactive VitD into active VitD (1.25-dihydroxyVitD/calcitriol). This step is highly regulated; therefore, supplementing with inactive VitD might not be sufficient to overcome the potential adverse health effects of VitD deficiency. The objective of this study was to conduct a systematic review and individual participant data (IPD) meta-analysis of data acquired from randomised placebo-controlled calcitriol trials (RCTs) to determine the effects of calcitriol on body weight and weight-related parameters.</div></div><div><h3>Methods</h3><div>Studies were identified from MEDLINE, EMBASE, and CENTRAL databases up to January 27, 2024, and excluded those involving dialysis or cancer patients. We obtained IPD from eligible trials and assessed bias using the Cochrane Collaboration risk-of-bias tool and methodological quality using the Heyland Methodological Quality Score. The study was prospectively registered with PROSPERO (CRD42017076202).</div></div><div><h3>Results</h3><div>Although none of the studies reported information regarding our primary objective, we obtained IPD for 411 patients, with 206 randomised to receive calcitriol and 205 to placebo. This dataset enabled us to conduct an IPD meta-analysis with 17,084 person-months of follow-up (median: 11 months). Meta-analysis showed that calcitriol does not alter body weight, BMI, waist circumference, fat mass or lean body mass compared to placebo. Adjusting for age and sex did not alter the outcomes.</div></div><div><h3>Conclusions</h3><div>In conclusion, this systematic review and IPD meta-analysis indicate that calcitriol does not affect body weight in normal-weight postmenopausal women and lean patients with type 1 diabetes nor in people suffering from obesity, type 2 diabetes and chronic kidney disease. Whether calcitriol lowers body weight in VitD-sufficient people with obesity remains to be elucidated.</div></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 11","pages":"Pages 99-105"},"PeriodicalIF":6.6,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142356829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periconceptional maternal intake of ultra-processed foods, energy and macronutrients the impact on imaging markers of early utero-placental vascular development: The rotterdam periconception cohort","authors":"Eline S. de Vos ,&nbsp;Annemarie G.M.G.J. Mulders ,&nbsp;Anton H.J. Koning ,&nbsp;Hilco S. Smit ,&nbsp;Lenie van Rossem ,&nbsp;Régine P.M. Steegers-Theunissen","doi":"10.1016/j.clnu.2024.09.033","DOIUrl":"10.1016/j.clnu.2024.09.033","url":null,"abstract":"<div><h3>Background &amp; aims</h3><div>The quantity and quality of maternal nutrition in the periconception period is an important determinant for embryonic and foetal development and subsequent pregnancy course and outcome. The intake of ultra-processed foods (UPF) has increased worldwide and adverse health outcomes have been reported. However, the impact of UPF intake on the placenta, essential for prenatal nourishment, is unknown. Therefore, we aim to investigate associations between the periconceptional maternal intake of UPF, energy and related macronutrients, and first-trimester utero-placental vascular development.</div></div><div><h3>Methods</h3><div>We included 214 ongoing pregnancies in the Virtual Placenta study, a subcohort of the Rotterdam periconception cohort. At enrollment, participants filled out a food frequency questionnaire from which we calculated the average daily energy from UPF, total energy intake and macronutrient intake from UPF. At 7-9-11 weeks of gestation, we performed sequential three-dimensional power Doppler ultrasounds of the first-trimester utero-placental vasculature. Virtual Organ Computer-aided AnaLysis (VOCAL) software, Virtual Reality segmentation and a skeletonization algorithm were applied to measure placental volume (PV), utero-placental vascular volume (uPVV) and generate the utero-placental vascular skeleton (uPVS). Absolute vascular morphology was quantified by assigning a morphologic characteristic to each voxel in the uPVS (end-, bifurcation-, crossing- or vessel point) and used to calculate density of vascular branching. Linear mixed models adjusted for confounders were used to investigate associations between maternal intake of UPF, total energy and macronutrients from UPF and PV, uPVV and uPVS characteristics.</div></div><div><h3>Results</h3><div>Energy intake from UPF and total energy intake were not consistently associated with imaging markers of utero-placental vascular development. Higher carbohydrate intake of 10 g/day from UPF was associated with increased uPVS trajectories (end points (β = 0.34, 95%CI = 0.07; 0.61), bifurcation points (β = 0.38, 95%CI = 0.05; 0.70), vessel points (β = 0.957, 95%CI = 0.21; 1.71). No associations were observed with PV.</div></div><div><h3>Conclusions</h3><div>Against our hypothesis, periconceptional maternal intake of UPF and total energy were not convincingly associated with impaired first-trimester utero-placental vascular development. Remarkably, the increased intake of carbohydrates from UPF, which is often considered ‘unhealthy’, is positively associated with first-trimester utero-placental vascular development. Given the complexity of diet, further research should elucidate what underlies these findings to be able to interpret how nutrition may impact utero-placental vascular development in early pregnancy.</div></div><div><h3>Clinical trial number</h3><div>This study is registered at the Dutch Trial Register (NTR6854).</div></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 11","pages":"Pages 46-53"},"PeriodicalIF":6.6,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142315994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}