Pub Date : 2024-01-01Epub Date: 2024-07-02DOI: 10.1159/000539883
Arin M VanWormer, Kelly Buchholtz, Jeffrey J VanWormer
Introduction: Alternatives are needed to traditional care to help patients manage pain and discomfort in acute care settings. Complementary and integrative therapies (CITs) involve alternative medicine practices that are assimilated into conventional care. The degree to which registered nurses (RNs) use CIT in acute care settings, however, remains unclear. This study identified determinants of CIT use among RNs in a US hospital.
Methods: A cross-sectional online survey was conducted. Nurse managers emailed invitations to study-eligible RNs, and the survey captured recent CIT use, as well as sociodemographic and training/experience exposures. Participants were employees in a western Wisconsin hospital. All participants were RNs at the target hospital and worked in acute care. CIT use was assessed with a single item that asked respondents to indicate which of 25 common CIT methods they have used or offered to patients.
Results: There were 164 respondents from 463 invited RNs (35% response rate). In the past 6 months, 79% reported the use of CIT with their patients. The most common practices were relaxed breathing, music therapy, essential oils, massage, and aromatherapy. The final multivariable logistic regression model found that RNs with ≥14 years of clinical experience had 72% lower odds of CIT use relative to those with 0-2 years of experience (p = 0.023). In addition, RNs who were married had 76% lower odds of CIT use relative to those not married (p = 0.017). Other factors such as age, gender, specialized CIT education, or nursing degree type had limited influence on CIT use.
Conclusion: The use of CIT was generally high in this sample of hospital RNs, particularly among those who were not married and who were trained more recently. Future research should examine RN-led CIT effectiveness on patient outcomes in clinical settings.
{"title":"Determinants of Complementary Therapy Use among Registered Nurses in an Acute Care Setting.","authors":"Arin M VanWormer, Kelly Buchholtz, Jeffrey J VanWormer","doi":"10.1159/000539883","DOIUrl":"10.1159/000539883","url":null,"abstract":"<p><strong>Introduction: </strong>Alternatives are needed to traditional care to help patients manage pain and discomfort in acute care settings. Complementary and integrative therapies (CITs) involve alternative medicine practices that are assimilated into conventional care. The degree to which registered nurses (RNs) use CIT in acute care settings, however, remains unclear. This study identified determinants of CIT use among RNs in a US hospital.</p><p><strong>Methods: </strong>A cross-sectional online survey was conducted. Nurse managers emailed invitations to study-eligible RNs, and the survey captured recent CIT use, as well as sociodemographic and training/experience exposures. Participants were employees in a western Wisconsin hospital. All participants were RNs at the target hospital and worked in acute care. CIT use was assessed with a single item that asked respondents to indicate which of 25 common CIT methods they have used or offered to patients.</p><p><strong>Results: </strong>There were 164 respondents from 463 invited RNs (35% response rate). In the past 6 months, 79% reported the use of CIT with their patients. The most common practices were relaxed breathing, music therapy, essential oils, massage, and aromatherapy. The final multivariable logistic regression model found that RNs with ≥14 years of clinical experience had 72% lower odds of CIT use relative to those with 0-2 years of experience (p = 0.023). In addition, RNs who were married had 76% lower odds of CIT use relative to those not married (p = 0.017). Other factors such as age, gender, specialized CIT education, or nursing degree type had limited influence on CIT use.</p><p><strong>Conclusion: </strong>The use of CIT was generally high in this sample of hospital RNs, particularly among those who were not married and who were trained more recently. Future research should examine RN-led CIT effectiveness on patient outcomes in clinical settings.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"390-395"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141491182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01Epub Date: 2024-08-09DOI: 10.1159/000540271
Xijing Yu, Mengyu Jin, Hui Huang, Fenfen Qiu, Lele Geng, Rong Guo, Xiaoyan Zhu, Xiuwu Hu
Objective: The objectively was to study the effect of long-snake moxibustion intervention on gut microbiota of patients with ankylosing spondylitis (AS) by 16S rDNA sequencing technology.
Methods: Thirty AS patients and 30 healthy volunteers were recruited and treated with long-snake moxibustion once a week for 12 weeks. AS patients were divided into pretreatment and posttreatment groups. VAS, BASDAI, and BASFI scores of AS patients before and after treatment were collected. 16S rDNA high-throughput sequencing technology was used to analyze the characteristics and differences of gut microbiota in AS patients before and after treatment and in healthy volunteers.
Results: VAS, BASDAI, and BASFI scores of AS patients after long-snake moxibustion treatment were lower than those of pretreatment group (p < 0.05). The results of gut microbiota alpha diversity showed that Ace and Chao1 index of the posttreatment group were higher than those of the health group (p < 0.05), but there was no statistical significance in Ace and Chao1 index between the pretreatment group and the posttreatment group (p > 0.05). Beta diversity analysis showed that mild classification aggregation occurred between the health group and the pretreatment group but did not reach a significant level, and there was no significant difference between the pretreatment group and the posttreatment group. The results of species abundance showed that, at the phylum level, compared with the health group, the relative abundance of Firmicutes and Proteobacteria decreased in the pretreatment group, while the relative abundance of Bacteroidetes and Actinobacteria increased. Compared with the pretreatment group, the relative abundance of Firmicutes increased and the relative abundance of Actinobacteria decreased in the posttreatment group, but there were no statistically significant differences in the above changes (p > 0.05). At the genus level, compared with the health group, the relative abundances of Subdoligranulum in the pretreatment group were increased (p < 0.05), while the relative abundances of Bifidobacterium and Streptococcus were decreased (p < 0.05). Compared with the pretreatment group, the relative abundance of Romboutsia in the posttreatment group was increased (p < 0.05).
Conclusion: Long-snake moxibustion can obviously improve the clinical symptoms of AS patients. The possible mechanism of action is related to regulating the abundance of gut microbiota, increasing beneficial bacteria, and restoring the homeostasis of gut microorganisms.
目的方法：招募30名强直性脊柱炎（AS）患者和30名健康志愿者，对其进行长蛇灸治疗，每周一次，连续12周。将 AS 患者分为治疗前和治疗后两组。收集治疗前后 AS 患者的 VAS、BASDAI 和 BASFI 评分。采用16S rDNA高通量测序技术分析了治疗前后强直性脊柱炎患者和健康志愿者肠道微生物群的特征和差异：结果：长蛇灸治疗后强直性脊柱炎患者的VAS、BASDAI和BASFI评分均低于治疗前（P<0.05）。肠道微生物群Alpha多样性结果显示，治疗后组的ace和chao1指数高于健康组（P<0.05），但治疗前组与治疗后组的ace和chao1指数差异无统计学意义（P>0.05）。Beta 多样性分析表明，健康组与处理前组之间存在轻度分类聚集，但未达到显著水平，处理前组与处理后组之间无显著差异。物种丰度结果表明，与健康组相比，在门的层次上，处理前组的固着菌和变形菌相对丰度下降，而类杆菌和放线菌相对丰度上升。与治疗前相比，治疗后组的固缩菌相对丰度增加，放线菌相对丰度减少，但上述变化差异无统计学意义（P>0.05）。在菌属水平上，与健康组相比，治疗前组 Subdoligranulum 的相对丰度升高（P<0.05），而双歧杆菌和链球菌的相对丰度降低（P<0.05）。与治疗前相比，治疗后组的隆突菌相对丰度增加（P<0.05）：结论：长蛇灸能明显改善强直性脊柱炎患者的临床症状。结论：长蛇灸能明显改善强直性脊柱炎患者的临床症状，其作用机制可能与调节肠道微生物群的丰度、增加有益菌、恢复肠道微生物的平衡有关。
{"title":"Effect of Long-Snake Moxibustion on Gut Microbiota of Patients with Ankylosing Spondylitis.","authors":"Xijing Yu, Mengyu Jin, Hui Huang, Fenfen Qiu, Lele Geng, Rong Guo, Xiaoyan Zhu, Xiuwu Hu","doi":"10.1159/000540271","DOIUrl":"10.1159/000540271","url":null,"abstract":"<p><strong>Objective: </strong>The objectively was to study the effect of long-snake moxibustion intervention on gut microbiota of patients with ankylosing spondylitis (AS) by 16S rDNA sequencing technology.</p><p><strong>Methods: </strong>Thirty AS patients and 30 healthy volunteers were recruited and treated with long-snake moxibustion once a week for 12 weeks. AS patients were divided into pretreatment and posttreatment groups. VAS, BASDAI, and BASFI scores of AS patients before and after treatment were collected. 16S rDNA high-throughput sequencing technology was used to analyze the characteristics and differences of gut microbiota in AS patients before and after treatment and in healthy volunteers.</p><p><strong>Results: </strong>VAS, BASDAI, and BASFI scores of AS patients after long-snake moxibustion treatment were lower than those of pretreatment group (p < 0.05). The results of gut microbiota alpha diversity showed that Ace and Chao1 index of the posttreatment group were higher than those of the health group (p < 0.05), but there was no statistical significance in Ace and Chao1 index between the pretreatment group and the posttreatment group (p > 0.05). Beta diversity analysis showed that mild classification aggregation occurred between the health group and the pretreatment group but did not reach a significant level, and there was no significant difference between the pretreatment group and the posttreatment group. The results of species abundance showed that, at the phylum level, compared with the health group, the relative abundance of Firmicutes and Proteobacteria decreased in the pretreatment group, while the relative abundance of Bacteroidetes and Actinobacteria increased. Compared with the pretreatment group, the relative abundance of Firmicutes increased and the relative abundance of Actinobacteria decreased in the posttreatment group, but there were no statistically significant differences in the above changes (p > 0.05). At the genus level, compared with the health group, the relative abundances of Subdoligranulum in the pretreatment group were increased (p < 0.05), while the relative abundances of Bifidobacterium and Streptococcus were decreased (p < 0.05). Compared with the pretreatment group, the relative abundance of Romboutsia in the posttreatment group was increased (p < 0.05).</p><p><strong>Conclusion: </strong>Long-snake moxibustion can obviously improve the clinical symptoms of AS patients. The possible mechanism of action is related to regulating the abundance of gut microbiota, increasing beneficial bacteria, and restoring the homeostasis of gut microorganisms.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"506-515"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The aim of this study was to analyze the effectiveness of acupuncture as an early intervention in the treatment of osteoporosis and prevention of osteoporosis.
Methods: This multicenter, randomized, controlled clinical trial was conducted in 226 patients with osteoporosis for 6 months. Participants were randomized to the control group (n = 110) and the acupuncture group (n = 116), both groups received basic treatment with daily calcium carbonate and vitamin D3 tablet (containing calcium 600 mg/tablet) supplementation (n = 116), and the acupuncture group received additional acupuncture treatment. Bone mineral density (BMD), Berg Balance Scale (BBS), bone metabolism indexes, and lower limb muscle strength and balance indexes were tested to evaluate the therapy outcomes of the two groups.
Results: After 6 months of treatment, BBS11 (p = 0.046), BBS12 (p = 0.042), and total BBS scores (p = 0) in the acupuncture group were significantly higher than those before treatment; comparing between groups, BBS8 in the acupuncture group was higher than that in the control group after 3 and 6 months, with statistically significant differences (p = 0.036 and 0.0270). After 6 months of treatment, the total BBS score of the acupuncture group was significantly higher than that of the control group, and the difference was statistically significant (p = 0.039). After 6 months of treatment, the BMD of total bone of femoral neck (p = 0.031) and hip joint (p = 0.013) in the acupuncture group was significantly higher than that before treatment, but there was no statistical difference with the control group. The time of five sit-to-stand test (FTSST) was shortened in the acupuncture group, and the difference was statistically significant (p = 0.023), but there was no significant change in the control group (p > 0.05). In addition, the specific sequences of blood phosphorus (p = 0.007), β-collagen (p = 0.009), and N-osteocalcin (p = 0.007) were significantly lower than before treatment after 3 months of acupuncture treatment, and the blood phosphorus level continued to decrease after 6 months of treatment (p = 0.007). In addition, the levels of N-osteocalcin in the acupuncture group were significantly lower than those in the control group after 3 months of treatment (p = 0.008).
Conclusion: Acupuncture can increase hip bone density, improve bone metabolism, reduce bone turnover rate, and improve body balance and lower limb muscle strength in patients with osteoporosis.
{"title":"Acupuncture in Treating Osteopenia: A Multicenter, Randomized, Controlled Clinical Trial.","authors":"Yidan Chen, Huaping Qiu, Lihua Xuan, Yabei Jin, Ruixiang Chen, Shitian Teng, Xiaoqing Jin","doi":"10.1159/000541440","DOIUrl":"10.1159/000541440","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to analyze the effectiveness of acupuncture as an early intervention in the treatment of osteoporosis and prevention of osteoporosis.</p><p><strong>Methods: </strong>This multicenter, randomized, controlled clinical trial was conducted in 226 patients with osteoporosis for 6 months. Participants were randomized to the control group (n = 110) and the acupuncture group (n = 116), both groups received basic treatment with daily calcium carbonate and vitamin D3 tablet (containing calcium 600 mg/tablet) supplementation (n = 116), and the acupuncture group received additional acupuncture treatment. Bone mineral density (BMD), Berg Balance Scale (BBS), bone metabolism indexes, and lower limb muscle strength and balance indexes were tested to evaluate the therapy outcomes of the two groups.</p><p><strong>Results: </strong>After 6 months of treatment, BBS11 (p = 0.046), BBS12 (p = 0.042), and total BBS scores (p = 0) in the acupuncture group were significantly higher than those before treatment; comparing between groups, BBS8 in the acupuncture group was higher than that in the control group after 3 and 6 months, with statistically significant differences (p = 0.036 and 0.0270). After 6 months of treatment, the total BBS score of the acupuncture group was significantly higher than that of the control group, and the difference was statistically significant (p = 0.039). After 6 months of treatment, the BMD of total bone of femoral neck (p = 0.031) and hip joint (p = 0.013) in the acupuncture group was significantly higher than that before treatment, but there was no statistical difference with the control group. The time of five sit-to-stand test (FTSST) was shortened in the acupuncture group, and the difference was statistically significant (p = 0.023), but there was no significant change in the control group (p > 0.05). In addition, the specific sequences of blood phosphorus (p = 0.007), β-collagen (p = 0.009), and N-osteocalcin (p = 0.007) were significantly lower than before treatment after 3 months of acupuncture treatment, and the blood phosphorus level continued to decrease after 6 months of treatment (p = 0.007). In addition, the levels of N-osteocalcin in the acupuncture group were significantly lower than those in the control group after 3 months of treatment (p = 0.008).</p><p><strong>Conclusion: </strong>Acupuncture can increase hip bone density, improve bone metabolism, reduce bone turnover rate, and improve body balance and lower limb muscle strength in patients with osteoporosis.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"516-528"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><strong>Background: </strong>For centuries, spring and other natural waters have been recommended as external or internal remedies for numerous diseases. For studies that examined the effects of drinking mineral waters against heartburn, gastroesophageal reflux disease (GERD), or functional dyspepsia, a systematic review is lacking.</p><p><strong>Objectives: </strong>The main aim of this systematic review was to examine the effects of drinking natural mineral waters on heartburn from various causes by identifying all published intervention studies and critically appraising their methods as well as summarizing their results.</p><p><strong>Methods: </strong>We systematically searched the largest medical literature database MEDLINE, further relevant web sources, and gray literature for randomized and nonrandomized trials, with or without control groups, up to September 2021 and no language restrictions. Further inclusion criteria were adult patients with heartburn, drinking cure with natural mineral water as the intervention, compared to no or other interventions (care-as-usual, waiting list). We defined the reduction of heartburn symptoms and duration of disease episodes as primary and quality of life as secondary outcomes. Two reviewers independently carried out the study quality assessments (risk of bias) using the National Institutes of Health-Study Quality Assessment Tools.</p><p><strong>Results: </strong>Nine trials comprising 393 patients from Italy, Russia, Ukraine, and Germany fulfilled all inclusion criteria. We identified three randomized controlled trials (all with poor methodological quality), plus six before-after (pre/post) intervention studies without a control group. The intervention groups of the three comparative trials seemed to show a stronger reduction of self-reported heartburn symptoms, and duration of heartburn episodes than the respective control groups; however, they all had poor methodological quality.</p><p><strong>Conclusion: </strong>Based on the best available evidence of clinical studies, we cannot recommend or advise against drinking natural mineral waters as a treatment for heartburn. The potential benefits of natural mineral waters that were reported in some studies with a lower evidence level (e.g., lacking a control group) should be verified by good quality randomized clinical trials with adequate comparison groups and longer follow-up periods.</p><p><p><title>Hintergrund</title>Seit Jahrhunderten werden Quell- und andere natürliche Wässer als äußerliche oder innerliche Heilmittel für zahlreiche Krankheiten empfohlen. Für Studien, die die Wirkung des Trinkens von Mineralwasser gegen Sodbrennen, gastroösophageale Refluxkrankheit (GERD) oder funktionelle Dyspepsie untersuchten, fehlt eine systematische Übersicht.<title>Zielsetzung</title>Das Hauptziel dieser systematischen Übersichtsarbeit war es, die Auswirkungen von Trinkkuren mit natürlichen Mineralwässern auf Sodbrennen verschiedener Ursachen zu untersuchen
{"title":"How Effective Is Drinking Natural Mineral Water against Heartburn from Functional Dyspepsia, Gastroesophageal Reflux Disease, or Other Causes? A Systematic Review of Clinical Intervention Studies.","authors":"Arun D'Souza, Katharina Zink, Jost Langhorst, Manfred Wildner, Carolin Stupp, Thomas Keil","doi":"10.1159/000536528","DOIUrl":"10.1159/000536528","url":null,"abstract":"<p><strong>Background: </strong>For centuries, spring and other natural waters have been recommended as external or internal remedies for numerous diseases. For studies that examined the effects of drinking mineral waters against heartburn, gastroesophageal reflux disease (GERD), or functional dyspepsia, a systematic review is lacking.</p><p><strong>Objectives: </strong>The main aim of this systematic review was to examine the effects of drinking natural mineral waters on heartburn from various causes by identifying all published intervention studies and critically appraising their methods as well as summarizing their results.</p><p><strong>Methods: </strong>We systematically searched the largest medical literature database MEDLINE, further relevant web sources, and gray literature for randomized and nonrandomized trials, with or without control groups, up to September 2021 and no language restrictions. Further inclusion criteria were adult patients with heartburn, drinking cure with natural mineral water as the intervention, compared to no or other interventions (care-as-usual, waiting list). We defined the reduction of heartburn symptoms and duration of disease episodes as primary and quality of life as secondary outcomes. Two reviewers independently carried out the study quality assessments (risk of bias) using the National Institutes of Health-Study Quality Assessment Tools.</p><p><strong>Results: </strong>Nine trials comprising 393 patients from Italy, Russia, Ukraine, and Germany fulfilled all inclusion criteria. We identified three randomized controlled trials (all with poor methodological quality), plus six before-after (pre/post) intervention studies without a control group. The intervention groups of the three comparative trials seemed to show a stronger reduction of self-reported heartburn symptoms, and duration of heartburn episodes than the respective control groups; however, they all had poor methodological quality.</p><p><strong>Conclusion: </strong>Based on the best available evidence of clinical studies, we cannot recommend or advise against drinking natural mineral waters as a treatment for heartburn. The potential benefits of natural mineral waters that were reported in some studies with a lower evidence level (e.g., lacking a control group) should be verified by good quality randomized clinical trials with adequate comparison groups and longer follow-up periods.</p><p><p><title>Hintergrund</title>Seit Jahrhunderten werden Quell- und andere natürliche Wässer als äußerliche oder innerliche Heilmittel für zahlreiche Krankheiten empfohlen. Für Studien, die die Wirkung des Trinkens von Mineralwasser gegen Sodbrennen, gastroösophageale Refluxkrankheit (GERD) oder funktionelle Dyspepsie untersuchten, fehlt eine systematische Übersicht.<title>Zielsetzung</title>Das Hauptziel dieser systematischen Übersichtsarbeit war es, die Auswirkungen von Trinkkuren mit natürlichen Mineralwässern auf Sodbrennen verschiedener Ursachen zu untersuchen","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"253-265"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11212782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140109564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><strong>Introduction: </strong>Music therapy and aromatherapy have been demonstrated effective for perioperative anxiety. However, the available studies have indicated discordant results about which adjunct treatment is better for perioperative anxiety. Therefore, we conducted this meta-analysis to explore the contrasting effects between them.</p><p><strong>Methods: </strong>Six electronic databases were searched for clinical trials evaluating the efficacy of music therapy compared with aromatherapy in alleviating perioperative anxiety. The primary outcome was the postintervention anxiety level. Secondary outcomes included differences in blood pressure and heart rate before and after the intervention as well as pain scores at intraoperative and postoperative time points. The study protocol was registered on PROSPERO (CRD42021249737).</p><p><strong>Results: </strong>Twelve studies (894 patients) were included. The anxiety level showed no statistically significant difference (SMD, 0.28; 95% CI: -0.12, 0.68; p = 0.17). The analysis of blood pressure and heart rate also did not identify statistically significant differences. Notably, the pain scores at the intraoperative time point suggested that aromatherapy was superior to music therapy (WMD, 0.29 cm; 95% CI: 0.05, 0.52; p = 0.02), while those at 4 h after surgery indicated the opposite results (WMD, -0.48 cm; 95% CI: -0.60, -0.36; p < 0.001).</p><p><strong>Conclusion: </strong>Low-to-moderate quality evidence suggests that music therapy and aromatherapy have similar potential to relieve perioperative anxiety. The potential data indicate that the two therapies have different benefits in intervention duration and age distribution. More direct high-quality comparisons are encouraged in the future to verify this point.</p><p><p><title>Einleitung</title>Musik- und Aromatherapie haben sich bei perioperativen Angstzuständen als wirksam erwiesen. Die verfügbaren Studien zeigten jedoch widersprüchliche Ergebnisse zur Frage, welche adjuvante Therapie bei perioperativen Angstzuständen besser ist. Daher führten wir die vorliegende Metaanalyse durch, um die unterschiedlichen Effekte der beiden Therapien zu untersuchen.<title>Methoden</title>Sechs (6) elektronische Datenbanken wurden nach klinischen Studien zur Wirksamkeit von Musiktherapie im Vergleich zur Aromatherapie bei der Linderung perioperativer Angstzustände durchsucht. Primäres Zielkriterium war das Angstniveau nach der Intervention. Die sekundären Zielkriterien umfassten die Unterschiede bei Blutdruck und Herzfrequenz vor und nach der Intervention sowie die Schmerz-Scores zu intra- und postoperativen Zeitpunkten. Das Studienprotokoll wurde auf PROSPERO (CRD42021249737) registriert.<title>Ergebnisse</title>Zwölf (12) Studien (894 Patienten) wurden eingeschlossen. Das Angstniveau zeigte keinen statistisch signifikanten Unterschied (SMD, 0,28; 95%-KI: −0,12, 0,68, <italic>p</italic> = 0,17) und auch die Analyse von Blutdruck und Herzfrequenz ergab
{"title":"Contrasting Effects of Music Therapy and Aromatherapy on Perioperative Anxiety: A Systematic Review and Meta-Analysis.","authors":"Si-Rui Xiang, Qiong Ma, Jing Dong, Yi-Feng Ren, Jun-Zhi Lin, Chuan Zheng, Ping Xiao, Feng-Ming You","doi":"10.1159/000538425","DOIUrl":"10.1159/000538425","url":null,"abstract":"<p><strong>Introduction: </strong>Music therapy and aromatherapy have been demonstrated effective for perioperative anxiety. However, the available studies have indicated discordant results about which adjunct treatment is better for perioperative anxiety. Therefore, we conducted this meta-analysis to explore the contrasting effects between them.</p><p><strong>Methods: </strong>Six electronic databases were searched for clinical trials evaluating the efficacy of music therapy compared with aromatherapy in alleviating perioperative anxiety. The primary outcome was the postintervention anxiety level. Secondary outcomes included differences in blood pressure and heart rate before and after the intervention as well as pain scores at intraoperative and postoperative time points. The study protocol was registered on PROSPERO (CRD42021249737).</p><p><strong>Results: </strong>Twelve studies (894 patients) were included. The anxiety level showed no statistically significant difference (SMD, 0.28; 95% CI: -0.12, 0.68; p = 0.17). The analysis of blood pressure and heart rate also did not identify statistically significant differences. Notably, the pain scores at the intraoperative time point suggested that aromatherapy was superior to music therapy (WMD, 0.29 cm; 95% CI: 0.05, 0.52; p = 0.02), while those at 4 h after surgery indicated the opposite results (WMD, -0.48 cm; 95% CI: -0.60, -0.36; p < 0.001).</p><p><strong>Conclusion: </strong>Low-to-moderate quality evidence suggests that music therapy and aromatherapy have similar potential to relieve perioperative anxiety. The potential data indicate that the two therapies have different benefits in intervention duration and age distribution. More direct high-quality comparisons are encouraged in the future to verify this point.</p><p><p><title>Einleitung</title>Musik- und Aromatherapie haben sich bei perioperativen Angstzuständen als wirksam erwiesen. Die verfügbaren Studien zeigten jedoch widersprüchliche Ergebnisse zur Frage, welche adjuvante Therapie bei perioperativen Angstzuständen besser ist. Daher führten wir die vorliegende Metaanalyse durch, um die unterschiedlichen Effekte der beiden Therapien zu untersuchen.<title>Methoden</title>Sechs (6) elektronische Datenbanken wurden nach klinischen Studien zur Wirksamkeit von Musiktherapie im Vergleich zur Aromatherapie bei der Linderung perioperativer Angstzustände durchsucht. Primäres Zielkriterium war das Angstniveau nach der Intervention. Die sekundären Zielkriterien umfassten die Unterschiede bei Blutdruck und Herzfrequenz vor und nach der Intervention sowie die Schmerz-Scores zu intra- und postoperativen Zeitpunkten. Das Studienprotokoll wurde auf PROSPERO (CRD42021249737) registriert.<title>Ergebnisse</title>Zwölf (12) Studien (894 Patienten) wurden eingeschlossen. Das Angstniveau zeigte keinen statistisch signifikanten Unterschied (SMD, 0,28; 95%-KI: −0,12, 0,68, <italic>p</italic> = 0,17) und auch die Analyse von Blutdruck und Herzfrequenz ergab","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"278-291"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140335037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><strong>Indroduction: </strong>Primary dysmenorrhea (PD) is a very common issue in young women that reduces the quality of women's lives. Both Western medicine and traditional Chinese medicine (TCM) provide several ways to treat PD; however, TCM treatment exhibits fewer side effects for the patient. Tuina massage and Chinese herbal compresses are considered forms of external TCM therapy that have been widely used to treat PD, especially in China. Therefore, to provide the most effective and safe treatment for PD, we combined Tuina and Chinese herbal compresses together in this observational study.</p><p><strong>Methods: </strong>A randomized controlled trial (RCT) consisting of 114 participants from the Shanghai University of Traditional Chinese Medicine who meet inclusion criteria will be divided into two groups in a 1:1 allocation ratio. The intervention group will receive Tuina combined with Chinese herbal compress therapy, while the control group will only receive Chinese herbal compress therapy. The treatment will be given 3 days before menstruation (once per day, 3 times per menstrual cycle). The primary outcome will be measured with the Visual Analog Scale (VAS). The secondary outcomes will be measured by the Dysmenorrhea Symptom Score, the Chinese Medical Dysmenorrhea Symptom Score, the Self-Rating Anxiety Scale (SAS), the Self-Rating Depression Scale (SDS), and the pain threshold at Guanyuan (CV4).</p><p><strong>Conclusion: </strong>This study will be the first RCT that will entail the combination of Tuina and Chinese herbal compresses to treat PD in the category of cold coagulation and blood stasis syndrome. If the results demonstrate that Tuina combined with a Chinese herbal compress is effective, we posit that this study will provide evidence-based references for a potential alternative treatment to treat PD in the future.</p><p><p><title>Einleitung</title>Die primäre Dysmenorrhoe (PD) ist ein Problem, das bei jungen Frauen sehr häufig auftritt und ihre Lebensqualität beeinträchtigt. Sowohl die westliche Medizin als auch die traditionelle chinesische Medizin (TCM) bieten verschiedene Therapiemöglichkeiten zur Behandlung der PD, allerdings ist die TCM mit weniger Nebenwirkungen für die Patientin verbunden. Tuina-Massage und chinesische Kräuterkompressen gelten als Formen der äußerlichen TCM-Therapie, die besonders in China zur Behandlung der PD weit verbreitet sind. Daher haben wir in dieser Beobachtungsstudie Tuina und chinesische Kräuterkompressen kombiniert, um eine möglichst wirksame und sichere Behandlung der PD bereitzustellen.<title>Methoden</title>Es handelt sich um eine randomisierte kontrollierte Studie (randomized controlled trial, RCT), bei der 114 Teilnehmerinnen der Shanghai University of Traditional Chinese Medicine, die die Einschlusskriterien erfüllen, im Verhältnis 1:1 in zwei Gruppen aufgeteilt werden. Die Interventionsgruppe erhält Tuina in Kombination mit chinesischen Kräuterkompressen, während die Kontrollgrupp
原发性痛经(PD)是年轻女性中非常常见的问题，降低了女性的生活质量。西医和中医都提供了几种治疗帕金森病的方法;然而，中医治疗对患者的副作用更少。推拿按摩和中药敷贴被认为是治疗帕金森病的中医外治形式，尤其在中国被广泛使用。因此，为了给PD提供最有效、最安全的治疗方法，我们在本观察性研究中将推拿与中药敷药相结合。方法:随机对照试验(RCT)选取114名来自上海中医药大学符合纳入标准的受试者，按1:1的比例分为两组。干预组采用推拿结合中药热敷疗法，对照组仅采用中药热敷疗法。治疗在月经前3天开始(每天1次，每个月经周期3次)。主要结果将用视觉模拟量表(VAS)测量。次要结局采用痛经症状评分、中医痛经症状评分、焦虑自评量表(SAS)、抑郁自评量表(SDS)和痛经阈值(CV4)进行测量。结论:本研究将是首个采用推拿结合中药敷贴治疗寒凝血瘀型帕金森病的RCT研究。如果结果表明推拿联合中药敷贴是有效的，我们认为本研究将为未来治疗PD的潜在替代疗法提供循证参考。EinleitungDie primäre痛经(PD) ist in Problem, das bei jungen Frauen sehr häufig auftritt und ire Lebensqualität beeinträchtigt。Sowohl die westliche Medizin也auch die traditionelle chinese Medizin (TCM) bieten verschiedene Therapiemöglichkeiten zur Behandlung der PD, allerdings ist die TCM mit weniger Nebenwirkungen fre die Patientin verbunden。推拿推拿与中医Kräuterkompressen gelten als Formen der äußerlichen中医治疗，中国中医治疗专家，中国中医治疗专家。她在北京的研究中心研究了中国和中国的关系Kräuterkompressen kombiniert，以及möglichst workksame and where Behandlung der PD bereitzustellen。方法:采用随机对照试验(RCT)，在上海中医药大学进行随机对照试验，在上海中医药大学进行随机对照试验，在上海中医药大学进行随机对照试验，在上海中医药大学进行随机对照试验，在上海中医药大学进行随机对照试验，在上海中医药大学进行随机对照试验，在上海中医药大学进行随机对照试验。模具干预组erhält中医联合推拿组Kräuterkompressen, während模具控制组，中医联合推拿组Kräuterkompressen erhält。Die Behandlung erfolt drei age vor der menstrual(末梢täglich，月经前梦)。Das primäre Zielkriterium wind and hand der visuellen Analogskala (VAS) gemessen。Die sekundären zielkriteren werden mithilfe des痛经症状-评分，des中医痛经症状-评分，der焦虑自评量表(SAS)， der抑郁自评量表(SDS)和der Schmerzschwelle am ganyan - akupunkturpunkt (CV4)。临床研究:随机对照研究:中医与中医联合研究:黄萎病与黄萎病联合研究:黄萎病与黄萎病联合研究:黄萎病与黄萎病联合研究:黄萎病分类:Kältekoagulation[1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1] [1]
{"title":"Effect of Tuina Combined with Chinese Herbal Compress on Primary Dysmenorrhea with Cold Coagulation and Blood Stasis Syndrome: A Study Protocol for a Randomized Controlled Trial.","authors":"Paphawarin Asawadethmetakul, Fangfang Xie, Chaoqun Xie, Jianwen Ma, Yanli You, Fei Yao","doi":"10.1159/000534335","DOIUrl":"10.1159/000534335","url":null,"abstract":"<p><strong>Indroduction: </strong>Primary dysmenorrhea (PD) is a very common issue in young women that reduces the quality of women's lives. Both Western medicine and traditional Chinese medicine (TCM) provide several ways to treat PD; however, TCM treatment exhibits fewer side effects for the patient. Tuina massage and Chinese herbal compresses are considered forms of external TCM therapy that have been widely used to treat PD, especially in China. Therefore, to provide the most effective and safe treatment for PD, we combined Tuina and Chinese herbal compresses together in this observational study.</p><p><strong>Methods: </strong>A randomized controlled trial (RCT) consisting of 114 participants from the Shanghai University of Traditional Chinese Medicine who meet inclusion criteria will be divided into two groups in a 1:1 allocation ratio. The intervention group will receive Tuina combined with Chinese herbal compress therapy, while the control group will only receive Chinese herbal compress therapy. The treatment will be given 3 days before menstruation (once per day, 3 times per menstrual cycle). The primary outcome will be measured with the Visual Analog Scale (VAS). The secondary outcomes will be measured by the Dysmenorrhea Symptom Score, the Chinese Medical Dysmenorrhea Symptom Score, the Self-Rating Anxiety Scale (SAS), the Self-Rating Depression Scale (SDS), and the pain threshold at Guanyuan (CV4).</p><p><strong>Conclusion: </strong>This study will be the first RCT that will entail the combination of Tuina and Chinese herbal compresses to treat PD in the category of cold coagulation and blood stasis syndrome. If the results demonstrate that Tuina combined with a Chinese herbal compress is effective, we posit that this study will provide evidence-based references for a potential alternative treatment to treat PD in the future.</p><p><p><title>Einleitung</title>Die primäre Dysmenorrhoe (PD) ist ein Problem, das bei jungen Frauen sehr häufig auftritt und ihre Lebensqualität beeinträchtigt. Sowohl die westliche Medizin als auch die traditionelle chinesische Medizin (TCM) bieten verschiedene Therapiemöglichkeiten zur Behandlung der PD, allerdings ist die TCM mit weniger Nebenwirkungen für die Patientin verbunden. Tuina-Massage und chinesische Kräuterkompressen gelten als Formen der äußerlichen TCM-Therapie, die besonders in China zur Behandlung der PD weit verbreitet sind. Daher haben wir in dieser Beobachtungsstudie Tuina und chinesische Kräuterkompressen kombiniert, um eine möglichst wirksame und sichere Behandlung der PD bereitzustellen.<title>Methoden</title>Es handelt sich um eine randomisierte kontrollierte Studie (randomized controlled trial, RCT), bei der 114 Teilnehmerinnen der Shanghai University of Traditional Chinese Medicine, die die Einschlusskriterien erfüllen, im Verhältnis 1:1 in zwei Gruppen aufgeteilt werden. Die Interventionsgruppe erhält Tuina in Kombination mit chinesischen Kräuterkompressen, während die Kontrollgrupp","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"20-29"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138444186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01Epub Date: 2024-02-08DOI: 10.1159/000536047
HuiYan Zhao, Ojin Kwon, Jiyun Cha, In Chul Jung, Purumea Jun, Jae Young Jang, Jung-Hee Jang
<p><strong>Introduction: </strong>Personalized diagnosis and therapy for Parkinson's disease (PD) are needed due to the clinical heterogeneity of PD. Syndrome differentiation (SD) in traditional medicine (TM) is a diagnostic method for customized therapy that comprehensively analyzes various symptoms and systemic syndromes. However, research identifying PD classification based on SD is limited.</p><p><strong>Methods: </strong>Ten electronic databases were systematically searched from inception to August 10, 2021. Clinical indicators, including 380 symptoms, 98 TM signs, and herbal medicine for PD diagnosed with SD, were extracted from 197 articles; frequency statistics on clinical indicators were conducted to classify several subtypes using hierarchical clustering.</p><p><strong>Results: </strong>Four distinct cluster groups were identified, each characterized by significant cluster-specific clinical indicators with 95% confidence intervals of distribution. Subtype 2 had the most severe progression, longest progressive duration, and highest association with greater late-stage PD-associated motor symptoms, including postural instability and gait disturbance. The action properties of the herbal formula and original SD presented in the data sources for subtype 2 were associated with Yin deficiency syndrome.</p><p><strong>Discussion/conclusion: </strong>Hierarchical clustering analysis distinguished various symptoms and TM signs among patients with PD. These newly identified PD subtypes may optimize the diagnosis and treatment with TM and facilitate prognosis prediction. Our findings serve as a cornerstone for evidence-based guidelines for TM diagnosis and treatment.</p><p><p><title>Einleitung</title>Eine personalisierte Diagnose und Therapie des Morbus Parkinson (MP) ist angesichts der ausgeprägten klinischen Heterogenität des MP unerlässlich. Die Syndromdifferenzierung (SD) ist in der traditionellen Medizin (TM) eine diagnostische Methode für eine maßgeschneiderte Therapie, bei der verschiedene Symptome und systemische Syndrome umfassend analysiert werden. Es liegen jedoch nur begrenzt Forschungsergebnisse in Bezug auf eine SD-basierte Klassifikation des MP vor.<title>Methoden</title>Zehn elektronische Datenbanken wurden systematisch durchsucht, von der Einrichtung bis zum 10. August 2021. Klinische Indikatoren einschließlich von 380 Symptomen, 98 TM-Zeichen sowie pflanzlichen Heilmitteln für mittels SD diagnostiziertem MP wurden aus 197 Artikeln extrahiert, und Häufigkeitsstatistiken der klinischen Indikatoren wurden erstellt, um mittels hierarchischem Clustering eine Reihe von Subtypen zu klassifizieren.<title>Ergebnisse</title>Vier verschiedene Cluster-Gruppen wurden identifiziert, die jeweils durch signifikante, Cluster-spezifische klinische Indikatoren mit 95% Konfidenzintervall der Verteilung gekennzeichnet waren. Subtyp 2 hatte den schwersten Verlauf, die längste Progressionsdauer und die stärkste Assoziation mit einem höheren Ausmaß von mot
{"title":"Exploring Traditional Medicine Diagnostic Classification for Parkinson's Disease Using Hierarchical Clustering.","authors":"HuiYan Zhao, Ojin Kwon, Jiyun Cha, In Chul Jung, Purumea Jun, Jae Young Jang, Jung-Hee Jang","doi":"10.1159/000536047","DOIUrl":"10.1159/000536047","url":null,"abstract":"<p><strong>Introduction: </strong>Personalized diagnosis and therapy for Parkinson's disease (PD) are needed due to the clinical heterogeneity of PD. Syndrome differentiation (SD) in traditional medicine (TM) is a diagnostic method for customized therapy that comprehensively analyzes various symptoms and systemic syndromes. However, research identifying PD classification based on SD is limited.</p><p><strong>Methods: </strong>Ten electronic databases were systematically searched from inception to August 10, 2021. Clinical indicators, including 380 symptoms, 98 TM signs, and herbal medicine for PD diagnosed with SD, were extracted from 197 articles; frequency statistics on clinical indicators were conducted to classify several subtypes using hierarchical clustering.</p><p><strong>Results: </strong>Four distinct cluster groups were identified, each characterized by significant cluster-specific clinical indicators with 95% confidence intervals of distribution. Subtype 2 had the most severe progression, longest progressive duration, and highest association with greater late-stage PD-associated motor symptoms, including postural instability and gait disturbance. The action properties of the herbal formula and original SD presented in the data sources for subtype 2 were associated with Yin deficiency syndrome.</p><p><strong>Discussion/conclusion: </strong>Hierarchical clustering analysis distinguished various symptoms and TM signs among patients with PD. These newly identified PD subtypes may optimize the diagnosis and treatment with TM and facilitate prognosis prediction. Our findings serve as a cornerstone for evidence-based guidelines for TM diagnosis and treatment.</p><p><p><title>Einleitung</title>Eine personalisierte Diagnose und Therapie des Morbus Parkinson (MP) ist angesichts der ausgeprägten klinischen Heterogenität des MP unerlässlich. Die Syndromdifferenzierung (SD) ist in der traditionellen Medizin (TM) eine diagnostische Methode für eine maßgeschneiderte Therapie, bei der verschiedene Symptome und systemische Syndrome umfassend analysiert werden. Es liegen jedoch nur begrenzt Forschungsergebnisse in Bezug auf eine SD-basierte Klassifikation des MP vor.<title>Methoden</title>Zehn elektronische Datenbanken wurden systematisch durchsucht, von der Einrichtung bis zum 10. August 2021. Klinische Indikatoren einschließlich von 380 Symptomen, 98 TM-Zeichen sowie pflanzlichen Heilmitteln für mittels SD diagnostiziertem MP wurden aus 197 Artikeln extrahiert, und Häufigkeitsstatistiken der klinischen Indikatoren wurden erstellt, um mittels hierarchischem Clustering eine Reihe von Subtypen zu klassifizieren.<title>Ergebnisse</title>Vier verschiedene Cluster-Gruppen wurden identifiziert, die jeweils durch signifikante, Cluster-spezifische klinische Indikatoren mit 95% Konfidenzintervall der Verteilung gekennzeichnet waren. Subtyp 2 hatte den schwersten Verlauf, die längste Progressionsdauer und die stärkste Assoziation mit einem höheren Ausmaß von mot","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"160-174"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139706249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><strong>Background: </strong>Several methods have been developed for cervical ripening. The data regarding the efficiency of evening primrose oil (EPO) are inconsistent. The purpose of this study was to investigate the outcomes of EPO use on cervical ripening in low-risk women with term pregnancy.</p><p><strong>Patients and methods: </strong>Low-risk term pregnant women referred to the obstetrics clinic of Imam Hossein Hospital in Tehran who were eligible according to the inclusion were randomized either to the case or control group. The case group received 1,000 mg vaginal EPO capsule, and the other group received a vaginal placebo capsule daily, similar to the original drug. The primary outcome was Bishop score, while the duration of labor phases and the inducing procedures were the secondary outcomes.</p><p><strong>Results: </strong>Forty-eight participants were randomized to each group and were considered for data analysis. Although Bishop score was not statistically different before the intervention, it was significantly higher in case group compared to the placebo group after the intervention (EPO = 5.83 ± 1.68, placebo = 5.19 ± 1.52, p value = 0.002). Four participants in the case group and two in the control group underwent cesarean section (p value = 0.677). The need for labor induction was significantly higher in the placebo group than EPO group (oxytocin injection: 10.4% vs. 31.3%, p value = 0.012, amniotomy: 75% vs. 41.7, p value = 0.001).</p><p><strong>Conclusion: </strong>The vaginal use of EPO could be considered as a safe and efficient approach for cervical ripening in low-risk term pregnant women.</p><p><p><title>Hintergrund</title>Es wurden verschiedene Methoden zur Zervixreifung entwickelt. Die Daten zur Wirksamkeit von Nachtkerzenöl (evening primrose oil, EPO) sind uneinheitlich. Mit dieser Studie sollen die Ergebnisse der Anwendung von EPO zur Zervixreifung bei Frauen mit niedrigem Risiko und termingerechter Schwangerschaft untersucht werden.<title>Patientinnen und Methoden</title>Schwangere Frauen mit niedrigem Risiko und termingerechter Schwangerschaft, die in die Geburtsklinik des Imam-Hossein-Krankenhauses in Teheran eingewiesen wurden und gemäss den Einschlusskriterien für die Teilnahme infrage kamen, wurden randomisiert der Fall- oder der Kontrollgruppe zugewiesen. Die Fallgruppe erhielt 1.000 mg EPO als Vaginalkapseln, während die andere Gruppe täglich eine vaginale Placebokapsel erhielt, die dem Originalpräparat ähnelte. Primäres Zielkriterium war der Bishop-Score und sekundäre Zielkriterien waren die Dauer der Wehenphasen sowie die Verfahren zur Geburtseinleitung.<title>Ergebnisse</title>Jeder Gruppe wurden randomisiert 48 Teilnehmerinnen zugewiesen und bei der Datenanalyse berücksichtigt. Während vor der Intervention kein statistisch signifikanter Unterschied im Bishop-Score bestand, fiel dieser nach der Intervention in der Fallgruppe signifikant höher aus als in der Placebogruppe (EPO = 5,83 ± 1,68, Placebo = 5,
{"title":"The Use of Evening Primrose Oil for Cervical Ripening in Low-Risk Women with Term Pregnancy: A Randomized Double-Blinded Controlled Trial.","authors":"Shideh Ariana, Nooshin Amjadi, Seyyedeh Neda Kazemi, Zahra Ahmadli","doi":"10.1159/000535585","DOIUrl":"10.1159/000535585","url":null,"abstract":"<p><strong>Background: </strong>Several methods have been developed for cervical ripening. The data regarding the efficiency of evening primrose oil (EPO) are inconsistent. The purpose of this study was to investigate the outcomes of EPO use on cervical ripening in low-risk women with term pregnancy.</p><p><strong>Patients and methods: </strong>Low-risk term pregnant women referred to the obstetrics clinic of Imam Hossein Hospital in Tehran who were eligible according to the inclusion were randomized either to the case or control group. The case group received 1,000 mg vaginal EPO capsule, and the other group received a vaginal placebo capsule daily, similar to the original drug. The primary outcome was Bishop score, while the duration of labor phases and the inducing procedures were the secondary outcomes.</p><p><strong>Results: </strong>Forty-eight participants were randomized to each group and were considered for data analysis. Although Bishop score was not statistically different before the intervention, it was significantly higher in case group compared to the placebo group after the intervention (EPO = 5.83 ± 1.68, placebo = 5.19 ± 1.52, p value = 0.002). Four participants in the case group and two in the control group underwent cesarean section (p value = 0.677). The need for labor induction was significantly higher in the placebo group than EPO group (oxytocin injection: 10.4% vs. 31.3%, p value = 0.012, amniotomy: 75% vs. 41.7, p value = 0.001).</p><p><strong>Conclusion: </strong>The vaginal use of EPO could be considered as a safe and efficient approach for cervical ripening in low-risk term pregnant women.</p><p><p><title>Hintergrund</title>Es wurden verschiedene Methoden zur Zervixreifung entwickelt. Die Daten zur Wirksamkeit von Nachtkerzenöl (evening primrose oil, EPO) sind uneinheitlich. Mit dieser Studie sollen die Ergebnisse der Anwendung von EPO zur Zervixreifung bei Frauen mit niedrigem Risiko und termingerechter Schwangerschaft untersucht werden.<title>Patientinnen und Methoden</title>Schwangere Frauen mit niedrigem Risiko und termingerechter Schwangerschaft, die in die Geburtsklinik des Imam-Hossein-Krankenhauses in Teheran eingewiesen wurden und gemäss den Einschlusskriterien für die Teilnahme infrage kamen, wurden randomisiert der Fall- oder der Kontrollgruppe zugewiesen. Die Fallgruppe erhielt 1.000 mg EPO als Vaginalkapseln, während die andere Gruppe täglich eine vaginale Placebokapsel erhielt, die dem Originalpräparat ähnelte. Primäres Zielkriterium war der Bishop-Score und sekundäre Zielkriterien waren die Dauer der Wehenphasen sowie die Verfahren zur Geburtseinleitung.<title>Ergebnisse</title>Jeder Gruppe wurden randomisiert 48 Teilnehmerinnen zugewiesen und bei der Datenanalyse berücksichtigt. Während vor der Intervention kein statistisch signifikanter Unterschied im Bishop-Score bestand, fiel dieser nach der Intervention in der Fallgruppe signifikant höher aus als in der Placebogruppe (EPO = 5,83 ± 1,68, Placebo = 5,","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"215-221"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139912235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01Epub Date: 2024-07-18DOI: 10.1159/000540213
Stéphanie Blockhuys, Pernilla Wittung-Stafshede
Background: Integrative oncology combines conventional and complementary, or integrative, therapies for a holistic treatment of cancer patients. Yoga is increasingly used as a complementary therapy for cancer patients, but there is no direct evidence for its effect on cancer pathophysiology like tumor response, or patient outcome like overall survival.
Summary: In this narrative review, we present in detail published studies from randomized clinical trials on complementary yoga therapy for cancer patients, including details about the biochemical mechanisms involved. Medicinal hatha yoga with breathing, postures, meditation, and relaxation enhances the quality of life of cancer patients by providing both psychological and physiological health benefits, highlighting the interconnectedness of mind and body. Yoga therapy reduces stress levels improving heart rate variability, leading to changes in hormonal regulation (e.g., cortisol), reduced oxidative stress, and improved immune function with reduced inflammation. Still, the biochemical effects of yoga on the cancer disease itself are unrevealed.
Key messages: More clinical and basic research is needed for further establishment of yoga as complementary therapy in oncology.
{"title":"Yoga as a Complementary Therapy for Cancer Patients: From Clinical Observations to Biochemical Mechanisms.","authors":"Stéphanie Blockhuys, Pernilla Wittung-Stafshede","doi":"10.1159/000540213","DOIUrl":"10.1159/000540213","url":null,"abstract":"<p><strong>Background: </strong>Integrative oncology combines conventional and complementary, or integrative, therapies for a holistic treatment of cancer patients. Yoga is increasingly used as a complementary therapy for cancer patients, but there is no direct evidence for its effect on cancer pathophysiology like tumor response, or patient outcome like overall survival.</p><p><strong>Summary: </strong>In this narrative review, we present in detail published studies from randomized clinical trials on complementary yoga therapy for cancer patients, including details about the biochemical mechanisms involved. Medicinal hatha yoga with breathing, postures, meditation, and relaxation enhances the quality of life of cancer patients by providing both psychological and physiological health benefits, highlighting the interconnectedness of mind and body. Yoga therapy reduces stress levels improving heart rate variability, leading to changes in hormonal regulation (e.g., cortisol), reduced oxidative stress, and improved immune function with reduced inflammation. Still, the biochemical effects of yoga on the cancer disease itself are unrevealed.</p><p><strong>Key messages: </strong>More clinical and basic research is needed for further establishment of yoga as complementary therapy in oncology.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"403-415"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01Epub Date: 2024-08-22DOI: 10.1159/000540263
Aliye Dogan-Gangal, Belgin Akin, Deniz Kocoglu-Tanyer
Introduction: Music is a non-pharmacological intervention often used to improve maternal mental health during pregnancy. However, there is limited evidence regarding the effectiveness of music-based interventions on maternal and fetal parameters during pregnancy. We present a systematic review of the available research literature on the effects of music interventions on maternal and fetal parameters.
Methods: A comprehensive literature search was conducted on the Web of Science, PubMed, ScienceDirect, Scopus, CINAHL, MEDLINE, Cochrane, ProQuest, and Turkish databases. The review included randomized controlled and quasi-experimental studies. Two independent authors evaluated the methodological quality of each study using the Quality Assessment Tool for Quantitative Studies. The study was registered in PROSPERO (CRD42018102914).
Results: The literature review yielded a total of 723 studies. Among these studies, 13 were included in this study. Most of the studies involving low-risk pregnant women reported that music had no effect on stress but reduced anxiety and depression. The effect of music on pregnant women's blood pressure varied depending on the presence of medical conditions that could affect their blood pressure. While some studies showed that music interventions effectively increased fetal movement and acceleration, the available findings were limited.
Conclusion: Healthcare professionals can use simple, cost-effective, and practical music interventions to improve maternal mental health during pregnancy without neglecting medical treatment. Future well-designed studies are recommended to investigate the effects of music on maternal psychological, physiological parameters and fetal parameters in high-risk pregnancies.
简介音乐是一种非药物干预措施，常用来改善孕期孕产妇的心理健康。然而，关于音乐干预对孕期孕产妇和胎儿参数的有效性的证据却很有限。我们对现有关于音乐干预对母体和胎儿参数影响的研究文献进行了系统性回顾：我们在 Web of Science、PubMed、Science Direct、Scopus、CINAHL、Medline、Cochrane、ProQuest 和 Turkish 数据库中进行了全面的文献检索。综述包括随机对照研究和准实验研究。两位独立作者使用定量研究质量评估工具对每项研究的方法学质量进行了评估。该研究已在 PROSPERO（CRD42018102914）上注册：结果：文献综述共收集到 723 项研究。结果：文献综述共收集到 723 项研究，其中 13 项被纳入本研究。大多数涉及低风险孕妇的研究报告称，音乐对压力没有影响，但能减轻焦虑和抑郁。音乐对孕妇血压的影响因孕妇是否患有可能影响血压的疾病而异。虽然一些研究表明音乐干预能有效增加胎动和加速，但现有研究结果有限：结论：医护人员可以使用简单、经济、实用的音乐干预措施来改善孕期孕产妇的心理健康，同时又不会忽视医疗。建议今后开展精心设计的研究，探讨音乐对高危妊娠中孕产妇心理、生理参数和胎儿参数的影响。
{"title":"Effect of Music-Based Interventions on Maternal and Fetal Parameters during Pregnancy: A Systematic Review.","authors":"Aliye Dogan-Gangal, Belgin Akin, Deniz Kocoglu-Tanyer","doi":"10.1159/000540263","DOIUrl":"10.1159/000540263","url":null,"abstract":"<p><strong>Introduction: </strong>Music is a non-pharmacological intervention often used to improve maternal mental health during pregnancy. However, there is limited evidence regarding the effectiveness of music-based interventions on maternal and fetal parameters during pregnancy. We present a systematic review of the available research literature on the effects of music interventions on maternal and fetal parameters.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted on the Web of Science, PubMed, ScienceDirect, Scopus, CINAHL, MEDLINE, Cochrane, ProQuest, and Turkish databases. The review included randomized controlled and quasi-experimental studies. Two independent authors evaluated the methodological quality of each study using the Quality Assessment Tool for Quantitative Studies. The study was registered in PROSPERO (CRD42018102914).</p><p><strong>Results: </strong>The literature review yielded a total of 723 studies. Among these studies, 13 were included in this study. Most of the studies involving low-risk pregnant women reported that music had no effect on stress but reduced anxiety and depression. The effect of music on pregnant women's blood pressure varied depending on the presence of medical conditions that could affect their blood pressure. While some studies showed that music interventions effectively increased fetal movement and acceleration, the available findings were limited.</p><p><strong>Conclusion: </strong>Healthcare professionals can use simple, cost-effective, and practical music interventions to improve maternal mental health during pregnancy without neglecting medical treatment. Future well-designed studies are recommended to investigate the effects of music on maternal psychological, physiological parameters and fetal parameters in high-risk pregnancies.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"540-550"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142035386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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