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Successful Maintenance Treatment of a Patient with Resistant Hyperthyroidism with Traditional Persian Medicine Recommendations: A Case Report and Literature Review. 用传统波斯医学建议成功维持治疗一名抗药性甲状腺功能亢进症患者:病例报告和文献综述。
IF 1.1 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-09-05 DOI: 10.1159/000541255
Mohammad Mahdi Parvizi, Sara Foolad, Ali Zeighami, Mohammad Reza Namazi, Mojtaba Heydari

Introduction: Hyperthyroidism is a common endocrinology condition that could affect several aspects of the patient's life.

Case presentation: We present a 27-year-old woman who was sent to the traditional Persian medicine (TPM) clinic with a diagnosis of uncontrolled chronic hyperthyroidism (lower levels of thyroid-stimulating hormone (TSH) and higher levels of T3 and T4) and its complications, such as developing exophthalmos, palpitations, anxiety, sleep problems, hair loss, and dry skin. The patient was under treatment with prednisolone and methimazole for up to 1 year, but no acceptable improvement was achieved. The patient received a package of TPM recommendations, which included lifestyle modification, Melissa officinalis herbal tea, and Persian barley water. The patient was followed for 1 year. After 2 months of follow-up of the patient, the level of TSH increased, and the level of T3 and T4 decreased. In addition, the patient's symptoms, including exophthalmos, palpitation, anxiety, sleep disturbance, and dryness of the skin, were improved considerably. After 3 months of consumption of the TPM-based regime and prescription, the serum levels of TSH, T3, and T4, of the patient were in normal ranges. In a 1-year follow-up of the patient, the patient's condition was stable and her thyroid function tests were normal. We hereby present the following case to be in line with the CAse REports (CARE) checklist.

Conclusion: It appears that TPM lifestyle recommendations, M. officinalis herbal tea, and Persian barley water were effective in treating the patient with uncontrolled hyperthyroidism. We recommend further studies and clinical trial designs in this regard.

简介甲状腺功能亢进症是一种常见的内分泌疾病,可能会影响患者生活的多个方面:我们为您介绍一位 27 岁的女性患者,她被送往传统波斯医学(TPM)诊所就诊,被诊断为不受控制的慢性甲状腺功能亢进症(促甲状腺激素(TSH)水平较低,T3 和 T4 水平较高)及其并发症,如眼球外翻、心悸、焦虑、睡眠问题、脱发和皮肤干燥。患者接受了长达一年的泼尼松龙和甲巯咪唑治疗,但病情没有得到可接受的改善。患者接受了一整套 TPM 建议,包括改变生活方式、香蜂草凉茶和波斯大麦水。对患者进行了为期一年的随访。随访两个月后,患者的促甲状腺激素水平上升,T3 和 T4 水平下降。此外,患者的眼球外翻、心悸、焦虑、睡眠障碍和皮肤干燥等症状也得到了明显改善。在服用基于 TPM 的疗法和处方三个月后,患者血清中的促甲状腺激素、T3 和 T4 水平均处于正常范围。在对患者一年的随访中,患者病情稳定,甲状腺功能检测正常。我们在此提出以下病例,以符合CAse REports(CARE)检查表的要求:结论:看来,TPM生活方式建议、香蜂草凉茶和波斯大麦水对治疗该名不受控制的甲状腺功能亢进症患者很有效。我们建议在这方面开展进一步的研究和临床试验设计。
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引用次数: 0
Society Bulletins · Gesellschaftsmitteilungen. 学会公告 - 学会公告。
IF 1.1 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-11-15 DOI: 10.1159/000542372
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引用次数: 0
Migraine in an Adolescent with a Pineal Cyst Treated with Classical Individualized Homeopathy: A Case Report. 用经典个性化顺势疗法治疗患有松果体囊肿的青少年偏头痛 - 病例报告。
IF 1.8 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-01 Epub Date: 2023-12-14 DOI: 10.1159/000535615
Katarina Lucija Glas, Amritha Belagaje, Seema Mahesh, George Vithoulkas

Background: Migraine is one of the leading causes of morbidity and disability in the world. Its prevalence ranges from 5 to 40% in the pediatric population, with about 50% of these headaches continuing to adulthood. Incidental diagnosis of pineal cysts (PCs) is on the rise with the evolution of imaging techniques; the causal relationship of PC and individuals with headache however remains controversial, and complete resolution is uncommon. Conventional medicine stresses on the importance of tailored therapy in the management of pediatric migraine.

Case report: An 11-year-old female, diagnosed with migraine with an aura and PC, was benefitted by individualized classical homeopathic therapy using the homeopathic preparation Phosphorous and Natrum muriaticum. The symptoms of migraine improved, and the incidentally diagnosed PC completely resolved during the course of treatment.

Conclusion: Individualized classical homeopathy may have a role in effectively treating migraines and PCs in the pediatric population. There is a need for further scientific investigation with well-designed studies to prove the effectiveness of this therapeutic method, taking care to maintain the individualization principle of classical homeopathy.

HintergrundMigräne ist eine der führenden Ursachen für Krankheitslast und Behinderung weltweit. Ihre Prävalenz bei Kindern und Jugendlichen liegt im Bereich von 5–40%; hiervon sind etwa 50% bis ins Erwachsenenalter von den Kopfschmerzen betroffen. Zufallsdiagnosen von Pinealiszysten (PC) kommen im Zuge des Fortschritts bei den bildgebenden Verfahren immer häufiger vor, jedoch ist ein kausaler Zusammenhang der PC mit Kopfschmerzen umstritten, und ein vollständige Rückbildung kommt nicht häufig vor. Die Schulmedizin betont, wie wichtig eine maßgeschneiderte Therapie bei der Behandlung der Migräne im Kindesalter ist.FallberichtEin 11-jähriges Mädchen, bei dem eine Migräne mit Aura und eine Pinealiszyste diagnostiziert wurde, profitierte von einer individualisierten klassisch-homöopathischen Therapie mit den homöopathischen Präparaten Phosphorus und Natrum muriaticum. Die Migränesymptome besserten sich, und die zufällig diagnostizierte Pinealiszyste bildete sich im Laufe der Behandlung vollständig zurück.SchlussfolgerungDie individualisierte klassische Homöopathie kann bei der wirksamen Behandlung von Migräne und Pinealiszysten bei Kindern und Jugendlichen eine Rolle spielen. Es bedarf weiterer wissenschaftlicher Untersuchungen mit gutem Studiendesign, um die Wirksamkeit dieser Behandlungsmethode nachzuweisen, wobei darauf zu achten ist, das Individualisierungsprinzip der klassischen Homöopathie aufrechtzuerhalten.

背景:偏头痛是全球发病率和致残率的主要原因之一。偏头痛在儿童中的发病率为 5-40%,其中约 50%的头痛会持续到成年。随着成像技术的发展,松果体囊肿(PC)的偶然诊断率正在上升;然而,PC 与头痛患者的因果关系仍存在争议,而且完全缓解的情况并不常见。传统医学强调,在治疗小儿偏头痛时,有针对性的治疗非常重要:病例报告:一名被诊断为有先兆偏头痛和松果体囊肿的 11 岁女性,接受了使用顺势疗法制剂 "磷 "和 "鼠曲草 "的个性化经典顺势疗法。在治疗过程中,偏头痛症状得到改善,偶然诊断出的松果体囊肿也完全消退:经典顺势疗法可有效治疗儿童偏头痛和松果体囊肿。有必要进行进一步的科学调查,通过精心设计的研究来证明这种治疗方法的有效性,同时注意保持经典顺势疗法的个性化原则。
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引用次数: 0
Acupuncture for Tinnitus: A Scoping Review of Clinical Studies. 针灸治疗耳鸣:临床研究综述。
IF 1.8 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-03-26 DOI: 10.1159/000538236
Keun Hee Lee, Min Hee Kim, Jaeho Kim, Hae Jeong Nam
<p><strong>Background: </strong>Acupuncture treatment for tinnitus has received attention owing to its potential as an alternative to conventional treatment modalities. We conducted a scoping review to identify detailed information on acupuncture treatment methods used in clinical studies and to provide useful information for practitioners, patients, and researchers.</p><p><strong>Methods: </strong>MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), Embase, Oriental Medicine Advanced Searching Integrated System (OASIS), Korean Research Information Sharing Service (RISS), DataBase Periodical Information Academic (DBPIA), and the China National Knowledge Infrastructure (CNKI) were searched from their inception to December 2023. This review included single-arm trials, open-label randomized controlled trials (RCTs), and double-blind RCTs using needle-type acupuncture to treat tinnitus in English, Chinese, and Korean. We investigated basic and detailed information on the acupuncture treatment methods, assessment methods, and study outcomes. Network analysis was also conducted to evaluate the centrality between acupoints in the double-blind RCTs.</p><p><strong>Results: </strong>We included 106 articles. There were 11 single-arm trials, 90 open-label RCTs, and 5 double-blind RCTs. Most (89.6%) of these studies were conducted in China. Manual acupuncture was the most common type of acupuncture in treatment group. A total of 119 acupuncture points were used 1,138 times. The most frequently used acupoints were local points around the ear (TE17, GB2, SI19, and TE21). Both local and distant acupoints were used simultaneously in these studies. The treatment duration of 20-39 days, 10 to 19 sessions of treatment, the mean acupuncture duration of 30 min, needle diameter of 0.30 mm × 40 mm, and needling depth over 30 mm and less than 50 mm were confirmed as the most common.</p><p><strong>Conclusion: </strong>These study outcomes will enable future acupuncture studies on tinnitus to perform more effective and standardized acupuncture treatments in selecting acupoints and procedures. Furthermore, the study has implications for informing clinicians and students about more impactful acupuncture strategies for addressing tinnitus.</p><p><p><title>Hintergrund</title>Die Anwendung von Akupunktur bei Tinnitus erhält seit einiger Zeit Aufmerksamkeit als potenzielle Alternative zu konventionellen Behandlungsmodalitäten. Wir führten einen Scoping-Review durch, um detaillierte Informationen zu den in klinischen Studien angewandten Akupunktur-Behandlungsmethoden zu sammeln und nützliche Informationen für Praktiker, Patienten und Forscher bereitzustellen.<title>Methoden</title>MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), Embase, Oriental Medicine Advanced Searching Integrated System (OASIS), Korean Research Information Sharing Service (RISS), DataBase Periodical Information Academic (DBPIA) und die China National Knowledge Infrastructure (
背景:针灸治疗耳鸣因其可替代传统治疗方法而备受关注。我们进行了一次范围综述,以确定临床研究中使用的针灸治疗方法的详细信息,并为从业人员、患者和研究人员提供有用信息:方法:检索了 Medline、Cochrane 对照试验中央注册中心 (CENTRAL)、EMBASE、东方医学高级检索综合系统 (OASIS)、韩国研究信息共享服务 (RISS)、数据库期刊信息学术 (DBPIA) 和中国国家知识基础设施 (CNKI),检索期从开始至 2023 年 12 月。本综述包括英文、中文和韩文的单臂试验、开放标签随机对照试验(RCT)和双盲 RCT。我们调查了针灸治疗方法、评估方法和研究结果的基本信息和详细信息。我们还进行了网络分析,以评估双盲 RCT 中穴位之间的中心性:我们共收录了 106 篇文章。其中有 11 项单臂试验、90 项开放标签 RCT 和 5 项双盲 RCT。这些研究大部分(89.6%)在中国进行。手法针灸是治疗组中最常见的针灸方法。共有 119 个穴位被使用了 1 138 次。最常用的穴位是耳周围的局部穴位(TE17、GB2、SI19 和 TE21)。在这些研究中,局部穴位和远处穴位被同时使用。治疗时间为 20 至 39 天,治疗次数为 10 至 19 次,平均针刺时间为 30 分钟,针刺直径为 0.30 毫米 x 40 毫米,针刺深度大于 30 毫米且小于 50 毫米:本研究成果将有助于今后的耳鸣针灸研究在选择穴位和操作过程中执行更有效、更标准化的针灸疗法。此外,该研究对临床医生和学生了解更有效的针灸治疗耳鸣的策略也具有重要意义。
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引用次数: 0
The Efficacy of the Herbal Formula of Bunium persicum and Coriandrum sativum on Clinical Symptoms of Patients with Functional Dyspepsia: A Double-Blind Randomized Controlled Trial. 杜仲和芫荽中药配方对功能性消化不良患者临床症状的疗效:一项双盲随机主动对照试验。
IF 1.1 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-07-17 DOI: 10.1159/000539472
Maryam Azimi, Mahboobeh Esfandiarpour, Mahboobeh Raeiszadeh, Faranak Salajegheh, Ali Saeidpour Parizi

Introduction: Functional dyspepsia (FD) is one of the most prevalent chronic disorders affecting up to 30% of the world population with considerable impairment of quality of life. This study evaluated the efficacy of the herbal preparation of Bunium persicum (Boiss.) B.Fedtsch. and Coriandrum sativum L. on symptom severity, symptom frequency, and quality of life of patients with FD.

Methods: This double-blind randomized controlled clinical trial, with parallel groups allocation ratio of 1:1, was conducted in a referral clinic of Afzalipour Hospital affiliated with Kerman University of Medical Sciences in Kerman, southeastern Iran. A total of 90 patients with FD (diagnosed based on the Rome IV criteria) were included in this study. The patients with complications during the intervention, pregnancy or lactation, a history of allergy to herbal drugs, use of other medication that affect the symptoms of FD during the study, and severe organic or psychiatric disorders were excluded. The participants received one capsule containing 500 mg of herbal preparation or placebo twice a day for 4 weeks and were subsequently followed up for 4 more weeks. Clinical outcomes were assessed via the Dyspepsia Severity Questionnaire, the Rome IV Diagnostic Questionnaire, and Nepean Dyspepsia Index Questionnaire.

Results: A total 40 participants in each group completed the follow-up period, and their data were analyzed statistically. All clinical outcomes showed significant improvements by herbal preparation compared to the placebo without serious side effects (p < 0.05).

Conclusions: This herbal preparation can significantly improve the quality of life, and symptoms of FD compared to placebo.

简介功能性消化不良(FD)是最普遍的慢性疾病之一,影响着全球多达 30% 的人口,严重损害了他们的生活质量。本研究评估了Bunium persicum (Boiss.) B.Fedtsch.和 Coriandrum Sativum L.草药配方对功能性消化不良患者症状严重程度、症状频率和生活质量的疗效:这项双盲随机对照临床试验在伊朗东南部克尔曼市的克尔曼医科大学附属阿夫扎利布尔医院转诊诊所进行,平行分组分配比例为 1:1。本研究共纳入了 90 名 FD 患者(根据罗马 IV 标准诊断)。排除了在干预期间出现并发症、怀孕或哺乳期、对草药有过敏史、在研究期间使用其他会影响 FD 症状的药物以及严重器质性或精神性疾病的患者。参与者每天两次服用含有 500 毫克草药配方或安慰剂的胶囊,每次一粒,连续服用 4 周,随后再随访 4 周。临床结果通过消化不良严重程度问卷、罗马IV诊断问卷和Nepean消化不良指数问卷进行评估:每组共有 40 名参与者完成了随访,并对他们的数据进行了统计分析。与安慰剂相比,中药配方的所有临床结果均有明显改善,且无严重副作用(P <0.05):结论:与安慰剂相比,该草药配方能明显改善 FD 的生活质量和症状。
{"title":"The Efficacy of the Herbal Formula of Bunium persicum and Coriandrum sativum on Clinical Symptoms of Patients with Functional Dyspepsia: A Double-Blind Randomized Controlled Trial.","authors":"Maryam Azimi, Mahboobeh Esfandiarpour, Mahboobeh Raeiszadeh, Faranak Salajegheh, Ali Saeidpour Parizi","doi":"10.1159/000539472","DOIUrl":"10.1159/000539472","url":null,"abstract":"<p><strong>Introduction: </strong>Functional dyspepsia (FD) is one of the most prevalent chronic disorders affecting up to 30% of the world population with considerable impairment of quality of life. This study evaluated the efficacy of the herbal preparation of Bunium persicum (Boiss.) B.Fedtsch. and Coriandrum sativum L. on symptom severity, symptom frequency, and quality of life of patients with FD.</p><p><strong>Methods: </strong>This double-blind randomized controlled clinical trial, with parallel groups allocation ratio of 1:1, was conducted in a referral clinic of Afzalipour Hospital affiliated with Kerman University of Medical Sciences in Kerman, southeastern Iran. A total of 90 patients with FD (diagnosed based on the Rome IV criteria) were included in this study. The patients with complications during the intervention, pregnancy or lactation, a history of allergy to herbal drugs, use of other medication that affect the symptoms of FD during the study, and severe organic or psychiatric disorders were excluded. The participants received one capsule containing 500 mg of herbal preparation or placebo twice a day for 4 weeks and were subsequently followed up for 4 more weeks. Clinical outcomes were assessed via the Dyspepsia Severity Questionnaire, the Rome IV Diagnostic Questionnaire, and Nepean Dyspepsia Index Questionnaire.</p><p><strong>Results: </strong>A total 40 participants in each group completed the follow-up period, and their data were analyzed statistically. All clinical outcomes showed significant improvements by herbal preparation compared to the placebo without serious side effects (p &lt; 0.05).</p><p><strong>Conclusions: </strong>This herbal preparation can significantly improve the quality of life, and symptoms of FD compared to placebo.</p>","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"416-426"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141562843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of the Utilization of Recognized Traditional and Complementary Medicine Service in Malaysia: A Secondary Analysis of a Cross-Sectional Population-Based Survey. 马来西亚使用公认的传统和补充医学服务的决定因素:对一项基于人口的横断面调查的二次分析。
IF 1.1 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-07-22 DOI: 10.1159/000540114
Suk Kuan Ng, Kimihiro Nishino, Zamtira Seman, Souphalak Inthaphatha, Eiko Yamamoto

Introduction: The utilization of traditional and complementary medicine (T&CM) services has witnessed a global increase over the past decades. Currently, seven practice areas are recognized in Malaysia: traditional Malay medicine (TMM), traditional Chinese medicine (TCM), traditional Indian medicine, homeopathy, Islamic medical practice, chiropractic, and osteopathy. Many global studies have investigated the general determinants of T&CM service utilization. However, there has been no comprehensive study reporting specific determinants of recognized T&CM service utilization. This study aimed to examine the prevalence and specific determinants of recognized T&CM service utilization in Malaysia at a national level.

Methods: This study is a secondary analysis of data from the National Health and Morbidity Survey (NHMS), a cross-sectional population-based survey conducted in Malaysia in 2015. A total of 6,207 respondents aged ≥18 years were included in this study. The associations of sociodemographic, health, and lifestyle factors with the utilization of the three T&CM service categories (TMM, TCM, and other T&CM) were examined using three separate logistic regression analyses.

Results: The prevalence of recognized T&CM service utilization in the last 12 months was 19.3%, with 15.0% for TMM, 3.9% for TCM, and 1.5% for other T&CM. The determinants of TMM service utilization were female sex; age range of 18-29 years; married or widowed/divorced status; Malay, indigenous, or other ethnicities; high household income; and being overweight/obese. The determinants of TCM service utilization were the age range of 30-49 years, urban residential location, Chinese ethnicity, and adequate fruit and vegetable intake. No specific determinants were identified for other T&CM.

Conclusion: This study provided novel evidence of a strong ethnocultural ownership toward traditional medicine. User profiles were distinctively different between varied T&CM services. Customized approaches to regulate, develop, and institutionalize specific T&CM services are crucial for fulfilling the unique needs of diverse communities.

导言:在过去的几十年里,全球对传统与补充医学(T&CM)服务的利用率不断提高。目前,马来西亚承认七种实践领域:传统马来医学、传统中医、传统印度医学、顺势疗法、伊斯兰医疗实践、脊椎按摩和整骨疗法。许多全球性研究都对使用传统中医服务的一般决定因素进行了调查。然而,还没有一项全面的研究报告了公认的中医药服务使用的具体决定因素。本研究旨在从国家层面研究马来西亚公认的 T&CM 服务利用率和具体决定因素:本研究对国家健康与发病率调查(NHMS)的数据进行了二次分析,NHMS是马来西亚于2015年开展的一项基于人口的横断面调查。本研究共纳入了6207名年龄≥18岁的受访者。通过三个独立的逻辑回归分析,研究了社会人口学、健康和生活方式因素与三类中医药服务(传统马来医药、传统中医药和其他中医药)使用情况的关系:过去 12 个月中使用过公认的中医药服务的比例为 19.3%,其中马来传统医药为 15.0%,传统中医药为 3.9%,其他中医药为 1.5%。使用马来传统医药服务的决定因素包括:女性;年龄在 18-29 岁之间;已婚或丧偶/离婚;马来、土著或其他族裔;家庭收入高;超重/肥胖。使用传统中医药服务的决定因素是 30-49 岁的年龄段、城市居住地、华裔以及充足的水果和蔬菜摄入量。结论:这项研究提供了新的证据,证明人们对传统医药有着强烈的民族文化认同感。各种传统医药服务的用户特征截然不同。为满足不同社区的独特需求,采用定制方法来规范、发展和制度化特定的传统医药服务至关重要。
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引用次数: 0
The Efficacy and Safety of Chinese Eye Exercise of Acupoints in Dry Eye Patients: A Randomized Controlled Trial. 中医穴位眼保健操对干眼症患者的疗效和安全性:随机对照试验。
IF 1.8 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-02-08 DOI: 10.1159/000536516
Pavasut Leedasawat, Paradi Sangvatanakul, Parunkul Tungsukruthai, Chuntida Kamalashiran, Pratya Phetkate, Promporn Patarajierapun, Kusuma Sriyakul
<p><strong>Introduction: </strong>Dry eye disorder (DED) is a growing global issue linked to excessive digital screen time. Chinese eye exercise of acupoint (CEA), a set of self-massages on shared Chinese acupuncture (CA), has been used to reduce visual-related ocular symptoms and possibly as an alternative treatment for DED. This study aimed to assess the efficacy and safety of CEA.</p><p><strong>Methods: </strong>A single-blind randomized controlled trial was conducted at Thammasat University Hospital in Thailand, recruiting 56 participants aged 20-60 years, equally divided into two groups: the treatment group with CEA and the control group with standard lid hygiene treatment (STD). The intervention program lasted 12 weeks.</p><p><strong>Main outcome measures: </strong>Ocular Surface Disease Index (OSDI), tear break-up time (TBUT), Schirmer-I test (SIT), corneal surface staining (CSS), and self-recorded forms for safety and adverse effects were measured at baseline, week 4, and week 12. An independent sample t test, paired t test, and repeated measures (ANOVA) were used to compare results between both groups, study visits, and primary and secondary outcome measurements, respectively. The p values <0.05 were considered statistically significant.</p><p><strong>Results: </strong>The characteristics were not statistically different between both groups at the baseline. The mean OSDI scores were significantly reduced in both groups at week 4 and week 12 compared to baseline (p value <0.05). Additionally, both CEA and STD showed significant improvement in TBUT and SIT (p value <0.05). CSS was significantly improved only in the CEA groups (p value <0.05). No significant differences were observed between the study groups, except for SIT at week 12 (p value <0.05). For the safety, there were no adverse side effects in either group.</p><p><strong>Conclusion: </strong>CEA seemed to be as effective as STD in improving the OSDI, TBUT, and SIT of DED without causing any side effects.</p><p><p><title>Einleitung</title>Das Trockene Auge (Dry eye disorder, DED) ist weltweit ein zunehmendes Problem, das mit übermässiger Bildschirmarbeit zusammenhängt. Die chinesische Augenübung der Akupunkturpunkte (Chinese eye exercise of acupoint, CEA), eine Reihe von Selbstmassagen an gemeinsamen CA-Akupunkturpunkten, wird zur Linderung visusbezogener Augensymptome und als mögliche alternative Behandlung für DED eingesetzt. Mit dieser Studie sollte die Wirksamkeit und Sicherheit von CEA bewertet werden.<title>Methoden</title>Am Thammasat-Universitätsklinikum in Thailand wurde eine einfach verblindete, randomisierte, kontrollierte Studie mit 56 Teilnehmern im Alter von 20 bis 60 Jahren durchgeführt, die zu gleichen Teilen zwei Gruppen zugewiesen wurden: die Behandlungsgruppe mit CEA und die Kontrollgruppe, die die Standard-Lidhygienebehandlung erhielt (STD). Das Interventionsprogramm dauerte 12 Wochen. Die Haupt-Zielkriterien, der Ocular Surface Disease Index (OS
简介干眼症(DED)是一个日益严重的全球性问题,与过长的数字屏幕时间有关。中式穴位眼保健操(CEA)是一套在共用 CA 穴位上进行自我按摩的方法,已被用于减轻与视觉相关的眼部症状,并可能作为 DED 的替代治疗方法。本研究旨在评估 CEA 的有效性和安全性:泰国 Thammasat 大学医院进行了一项单盲随机对照试验,招募了 56 名年龄在 20-60 岁之间的参与者,平均分为两组:CEA 治疗组和标准眼睑卫生治疗(STD)对照组。干预计划为期 12 周:在基线、第 4 周和第 12 周测量眼表疾病指数 (OSDI)、泪液破裂时间 (TBUT)、Schirmer I 测试 (SIT)、角膜表面染色 (CSS),以及安全性和不良反应自我记录表。分别采用独立样本 t 检验、配对 t 检验和重复测量(方差分析)来比较两组之间、研究访问之间以及主要和次要结果测量之间的结果。P值小于0.05为有统计学意义:结果:两组基线特征无统计学差异。与基线相比,两组患者在第4周和第12周的平均OSDI评分均明显降低(P值均小于0.05)。此外,CEA 和 STD 组的 TBUT 和 SIT 均有明显改善(P 值 < 0.05)。只有 CEA 组的 CSS 有明显改善(p 值 < 0.05)。除第 12 周的 SIT(p 值 < 0.05)外,各研究组之间未观察到明显差异。在安全性方面,两组均无不良副作用:CEA在改善DED的OSDI、TBUT和SIT方面似乎与STD一样有效,且不会产生任何副作用。
{"title":"The Efficacy and Safety of Chinese Eye Exercise of Acupoints in Dry Eye Patients: A Randomized Controlled Trial.","authors":"Pavasut Leedasawat, Paradi Sangvatanakul, Parunkul Tungsukruthai, Chuntida Kamalashiran, Pratya Phetkate, Promporn Patarajierapun, Kusuma Sriyakul","doi":"10.1159/000536516","DOIUrl":"10.1159/000536516","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Dry eye disorder (DED) is a growing global issue linked to excessive digital screen time. Chinese eye exercise of acupoint (CEA), a set of self-massages on shared Chinese acupuncture (CA), has been used to reduce visual-related ocular symptoms and possibly as an alternative treatment for DED. This study aimed to assess the efficacy and safety of CEA.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A single-blind randomized controlled trial was conducted at Thammasat University Hospital in Thailand, recruiting 56 participants aged 20-60 years, equally divided into two groups: the treatment group with CEA and the control group with standard lid hygiene treatment (STD). The intervention program lasted 12 weeks.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main outcome measures: &lt;/strong&gt;Ocular Surface Disease Index (OSDI), tear break-up time (TBUT), Schirmer-I test (SIT), corneal surface staining (CSS), and self-recorded forms for safety and adverse effects were measured at baseline, week 4, and week 12. An independent sample t test, paired t test, and repeated measures (ANOVA) were used to compare results between both groups, study visits, and primary and secondary outcome measurements, respectively. The p values &lt;0.05 were considered statistically significant.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The characteristics were not statistically different between both groups at the baseline. The mean OSDI scores were significantly reduced in both groups at week 4 and week 12 compared to baseline (p value &lt;0.05). Additionally, both CEA and STD showed significant improvement in TBUT and SIT (p value &lt;0.05). CSS was significantly improved only in the CEA groups (p value &lt;0.05). No significant differences were observed between the study groups, except for SIT at week 12 (p value &lt;0.05). For the safety, there were no adverse side effects in either group.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;CEA seemed to be as effective as STD in improving the OSDI, TBUT, and SIT of DED without causing any side effects.&lt;/p&gt;&lt;p&gt;&lt;p&gt;&lt;title&gt;Einleitung&lt;/title&gt;Das Trockene Auge (Dry eye disorder, DED) ist weltweit ein zunehmendes Problem, das mit übermässiger Bildschirmarbeit zusammenhängt. Die chinesische Augenübung der Akupunkturpunkte (Chinese eye exercise of acupoint, CEA), eine Reihe von Selbstmassagen an gemeinsamen CA-Akupunkturpunkten, wird zur Linderung visusbezogener Augensymptome und als mögliche alternative Behandlung für DED eingesetzt. Mit dieser Studie sollte die Wirksamkeit und Sicherheit von CEA bewertet werden.&lt;title&gt;Methoden&lt;/title&gt;Am Thammasat-Universitätsklinikum in Thailand wurde eine einfach verblindete, randomisierte, kontrollierte Studie mit 56 Teilnehmern im Alter von 20 bis 60 Jahren durchgeführt, die zu gleichen Teilen zwei Gruppen zugewiesen wurden: die Behandlungsgruppe mit CEA und die Kontrollgruppe, die die Standard-Lidhygienebehandlung erhielt (STD). Das Interventionsprogramm dauerte 12 Wochen. Die Haupt-Zielkriterien, der Ocular Surface Disease Index (OS","PeriodicalId":10541,"journal":{"name":"Complementary Medicine Research","volume":" ","pages":"149-159"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139706250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Society Bulletins · Gesellschaftsmitteilungen. 学会公告 - 学会公告。
IF 1.8 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-01-25 DOI: 10.1159/000536353
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引用次数: 0
Acupuncture Point Selection Patterns for Chemotherapy-Induced Nausea and Vomiting: A Data Mining Analysis. 化疗所致恶心呕吐的穴位选择模式:数据挖掘分析
IF 1.1 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-05-06 DOI: 10.1159/000538839
Zi Ke, Hongruyu Chen, Yong Zhao, Jixian Ke, Youqiong Xie, Runxin Zeng, Yini Hua, Zhihao Xiong, Xuanxuan Wang

Introduction: Chemotherapy-induced nausea and vomiting (CINV) significantly impacts the quality of life of cancer patients undergoing treatment, often leading to treatment interruptions and compromised adherence to therapy. Our objective was to identify patterns for selecting the optimal acupoints and explore the treatment principles behind forming effective acupoint combinations for CINV.

Methods: Clinical trials were retrieved from eight databases. Descriptive statistics analysis was performed, followed by association rule mining, network analysis, hierarchical cluster analysis, and correlation analysis, all implemented with R software.

Results: In summary, this study investigated the potential acupoints and combinations for CINV treatment in 104 published controlled clinical trials and randomized controlled trials. 104 prescriptions involving 48 acupoints were extracted. ST36, PC6, CV12, SP4, LI4, and ST25 appeared to be the most frequently used acupoints for CINV. Stomach Meridian, Conception Vessel (Renmai), and Pericardium Meridian were the most common selected meridians. The lower limbs, chest, and abdomen appeared as the predominant sites for acupoint selection. Co-occurrence network analysis indicated that ST36, PC6, and CV12 were central key node acupoints. The clustering analysis displayed the treatment principle of "harmonizing the stomach, stopping vomiting, and descending counterflow." Association rule mining revealed that the combination of CV4, CV12, ST36, CV6, and PC6 emerged as the optimal acupoint combination for effectively treating CINV.

Conclusion: Overall, our research provides evidence-based optimal acupuncture prescription for acupuncturists to treat CINV and presents a complementary therapy for chemotherapy physicians as well as patients to address CINV symptoms.

简介化疗引起的恶心和呕吐(CINV)严重影响接受治疗的癌症患者的生活质量,往往导致治疗中断和治疗依从性受损。我们的目标是找出选择最佳穴位的模式,并探索形成有效穴位组合治疗 CINV 的治疗原则:方法:从八个数据库中检索临床试验。方法:从 8 个数据库中检索临床试验,进行描述性统计分析,然后用 R 软件进行关联规则挖掘、网络分析、层次聚类分析和相关性分析:综上所述,本研究调查了 104 项已发表的临床对照试验和随机对照试验中治疗 CINV 的潜在穴位和组合。提取了涉及 48 个穴位的 104 个处方。ST36、PC6、CV12、SP4、LI4 和 ST25 似乎是治疗 CINV 最常用的穴位。胃经、督脉(任脉)和心包经是最常被选取的经络。下肢、胸部和腹部是穴位选择的主要部位。共现网络分析显示,ST36、PC6 和 CV12 是中心关键节点穴位。聚类分析显示了 "和胃、止呕、降逆 "的治疗原则。关联规则挖掘显示,CV4、CV12、ST36、CV6 和 PC6 的组合是有效治疗 CINV 的最佳穴位组合:总之,我们的研究为针灸师治疗 CINV 提供了以证据为基础的最佳针灸处方,并为化疗医生和患者解决 CINV 症状提供了一种辅助疗法。
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Society Bulletins · Gesellschaftsmitteilungen. 学会公告 - 学会公告。
IF 1.8 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-01-01 Epub Date: 2024-05-16 DOI: 10.1159/000538698
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Complementary Medicine Research
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