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Corrigendum to “Personalized virtual reality exposure for panic disorder and agoraphobia: A preliminary neurophysiological study” [Comprehensive Psychiatry Volume 129 (2024) 152447] 针对恐慌症和广场恐惧症的个性化虚拟现实暴露:一项初步神经生理学研究"[《综合精神病学》第 129 卷(2024 年)第 152447 页]的更正。
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-01 DOI: 10.1016/j.comppsych.2024.152537
Han Wool Jung , Ki Won Jang , Sangkyu Nam , Moo Eob Ahn , Sang-Kyu Lee , Yeo Jin Kim , Jae-Kyoung Shin , Ju Hyun Park , Daeyoung Roh
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引用次数: 0
Longitudinal pathways from emotional abuse to problematic gaming in adolescents: The role of psychoticism 青少年从情绪虐待到问题游戏的纵向路径:精神病的作用。
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-01 DOI: 10.1016/j.comppsych.2024.152569
Valeria Verrastro , Valeria Saladino , Fiorenza Giordano , Danilo Calaresi

Background

Problematic gaming (PG) has emerged as a major concern due to its potential impact on adolescents' everyday lives. Emotional abuse (EA) and psychoticism are considered factors influencing PG, but their long-term interactions have not been extensively studied. This research investigates these relationships over time using the Interaction of Person–Affect–Cognition–Execution (I-PACE) model. Methods: The study involved 1902 Italian adolescents (mean age = 15.45, SD = 1.10) in a three-wave longitudinal study. Surveys were conducted at the beginning (T1), after six months (T2), and after twelve months (T3). Structural equation modeling (SEM) was used to evaluate bidirectional relationships and mediation effects among the variables. Results: The findings indicated that EA consistently predicted both psychoticism and PG, while psychoticism consistently predicted PG. However, psychoticism did not predict EA, and PG did not predict either EA or psychoticism. Significant mediation effects were found from EA at T1 to PG at T3 through EA at T2, psychoticism at T2, and PG at T2, as well as from psychoticism at T1 to PG at T3 through psychoticism at T2 and PG at T2. No significant indirect effect was observed from psychoticism at T2 to PG at T3 through EA at T2. Conclusions: The results suggest that adolescents experiencing EA are more prone to PG, with psychoticism worsening this effect. Effective interventions might include emotional support programs and therapies targeting psychoticism traits. Combining these approaches could improve treatment outcomes for adolescents with PG.
背景:问题游戏(PG)由于其对青少年日常生活的潜在影响而成为人们关注的主要问题。情绪虐待(EA)和精神病被认为是影响PG的因素,但它们之间的长期相互作用尚未得到广泛研究。本研究利用人-情感-认知-执行(I-PACE)模型研究这些关系随时间的变化。方法:对1902名意大利青少年(平均年龄15.45岁,SD = 1.10)进行三波纵向研究。调查分别在开始(T1)、6个月(T2)和12个月(T3)进行。采用结构方程模型(SEM)评价变量之间的双向关系和中介效应。结果:EA对精神质和PG的预测一致,而精神质对PG的预测一致。然而,精神质不能预测EA, PG不能预测EA和精神质。从T1 EA到T3 PG,再到T2 EA,再到T2精神质,再到T2 PG,以及从T1精神质到T3 PG,再到T2精神质和T2 PG,均存在显著的中介作用。从T2的精神状态到T3的PG,再到T2的EA,没有观察到明显的间接影响。结论:结果表明,经历EA的青少年更容易发生PG,而精神状态会加重这种影响。有效的干预措施可能包括情感支持计划和针对精神病特征的治疗。结合这些方法可以改善青少年PG的治疗效果。
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引用次数: 0
Towards understanding and addressing mental health challenges in Africa: An integrated perspective 理解和应对非洲的精神卫生挑战:综合视角。
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-01 DOI: 10.1016/j.comppsych.2024.152565
Christine Lochner , Symon M. Kariuki
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引用次数: 0
Mental health and well-being in adolescent and young adult refugees in Sweden: A cross-sectional study of accompanied and unaccompanied individuals 瑞典青少年和青年难民的心理健康和福祉:有伴和无人陪伴个人的横断面研究。
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-01 DOI: 10.1016/j.comppsych.2024.152571
Erica Mattelin , Amal R. Khanolkar , Johan Andersson , Hania Kutabi , Laura Korhonen

Background

Currently, approximately 100 million people are displaced worldwide, including children and young adults. Previous studies showed exposure to violence and posttraumatic stress disorder (PTSD) are common in this sub-population. However, we still lack comprehensive data on well-being, mental health, and the ability to function.

Methods

This study included 291 adolescent (aged 12–17 years) and young adult (18–25 years) refugees recruited nationwide in Sweden between 2019 and 2022. Sociodemographic, mental health and well-being-related data (well-being, post-traumatic stress symptoms, psychiatric diagnoses, and functional ability) were collected using semi-structured interviews with structured components. Associations between accompanied status and well-being/depression/suicidal thoughts, generalized anxiety disorder/panic disorder/PTSD symptoms, and functional ability were analyzed using linear and logistic regression, adjusted for age, gender, parental education, asylum status, and region of origin.

Findings

Most study participants (mean age 17·9 years) originated from the Middle East and North Africa (70·6 %) or Sub-Saharan Africa (27·0 %). 16·1 % of adolescents and 32·3 % of young adults were unaccompanied. Nearly the entire study sample had experienced violence (92·8 %). However, the sample had a low prevalence of psychiatric diagnoses. For example, only 5·9 % fulfilled the criteria for clinical depression. Self-reported well-being (WHO-5, 71·09 (23·91)) and observer-rated functional ability (GAS/GAF, 81·76 (14·15)) were high. There were no significant differences in diagnosis prevalence by gender. However, significant differences existed between accompanied versus unaccompanied groups. Being an unaccompanied refugee individual was associated with a higher risk of suicidal thoughts, adjusted odds ratio, aOR 5·66 (95 % CI 2·15–14·88), higher rates of post-traumatic stress disorder symptoms β = 0·72 (0·39–1·05), lower mental well-being β = −10·86 95 % CI (−18·23— -3·48) and lower functional ability β = −9·38 (−13·84— -4·92). There were no differences in outcomes by gender except for worse well-being in males (β = 6·83 (1·01–12·66)).

Interpretation

In this sample, we found lower prevalence rates for all psychiatric diagnoses compared to earlier published studies. Being an unaccompanied refugee individual was a risk factor for all adverse outcomes. Future studies need to confirm the relatively low rates of psychiatric diagnoses. Regardless, the results highlight the heterogeneous needs among newly arrived refugees.
背景:目前,全世界大约有1亿人流离失所,其中包括儿童和年轻人。先前的研究表明,暴露于暴力和创伤后应激障碍(PTSD)在这一人群中很常见。然而,我们仍然缺乏关于幸福感、心理健康和功能的全面数据。方法:本研究纳入了2019年至2022年在瑞典全国招募的291名青少年(12-17岁)和年轻人(18-25岁)难民。社会人口学、心理健康和幸福相关数据(幸福感、创伤后应激症状、精神诊断和功能能力)采用带有结构化成分的半结构化访谈收集。使用线性和逻辑回归分析伴随状态与幸福感/抑郁/自杀念头、广泛性焦虑障碍/惊恐障碍/创伤后应激障碍症状和功能能力之间的关系,并根据年龄、性别、父母教育程度、庇护状态和原籍地区进行调整。研究结果:大多数研究参与者(平均年龄17.9岁)来自中东和北非(70.6%)或撒哈拉以南非洲(27.0%)。16.1%的青少年和32.3%的青年是无人陪伴的。几乎所有的研究样本都经历过暴力(92.8%)。然而,样本中精神病诊断的患病率较低。例如,只有5.9%的人符合临床抑郁症的标准。自我报告的幸福感(WHO-5, 71·09(23·91))和观察者评价的功能能力(GAS/GAF, 81·76(14·15))较高。不同性别的诊断患病率无显著差异。然而,陪伴组和无人陪伴组之间存在显著差异。作为一个无人陪伴的难民个体与较高的自杀念头风险相关,调整比值比为5.66 (95% CI 2.15 - 14.88),较高的创伤后应激障碍症状发生率β = 0.72(0.39 - 1.05),较低的心理幸福感β = - 10.86 95% CI(- 18.23 - - 3.48)和较低的功能能力β = - 9.38(- 13.84 - - 4.92)。除男性幸福感较差(β = 6·83(1·01-12·66))外,性别间无差异。解释:在这个样本中,我们发现与早期发表的研究相比,所有精神病诊断的患病率都较低。作为一个无人陪伴的难民个人是所有不利结果的一个风险因素。未来的研究需要证实相对较低的精神病诊断率。无论如何,调查结果凸显了新抵达难民的不同需求。
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引用次数: 0
Pharmacological management of gambling disorder: A systematic review and network meta-analysis 赌博障碍的药物治疗:系统综述和网络荟萃分析。
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-01 DOI: 10.1016/j.comppsych.2024.152566
Konstantinos Ioannidis , Cinzia Del Giovane , Charidimos Tzagarakis , Jeremy E. Solly , Samuel J. Westwood , Valeria Parlatini , Henrietta Bowden-Jones , Jon E. Grant , Samuele Cortese , Samuel R. Chamberlain

Background

Clinical guidelines remain unclear on which medications for gambling disorder are to be preferred in terms of efficacy and tolerability. We aimed to compare pharmacological treatments for gambling disorder in terms of efficacy and tolerability, using network meta-analysis (NMA).

Methods

Based on our pre-registered protocol [CRD42022329520], a structured search was conducted across broad range of databases, for double-blind randomized controlled trials (RCTs) of medications for gambling disorder. Data were independently extracted by two researchers. We used standardized mean differences (SMD) using Hedges' g to measure the efficacy outcomes, and for the effect for tolerability we used dropout rate due to medication side effects, expressed as odds ratio (OR). Confidence in the network estimates was assessed using the CINeMA framework. We followed the PRISMA-NMA guidelines for this work. Outcomes were gambling symptom severity and quality of life (for efficacy), and tolerability.

Findings

We included 22 RCTs in the systematic review and 16 RCTs (n = 977 participants) in the NMA. Compared with placebo, moderate confidence evidence indicated that nalmefene [Standardized Mean Difference (SMD): −0.86; 95 % confidence interval (CI: −1.32,-0.41)] reduced gambling severity, followed by naltrexone (SMD: -0.42; 95 %CI: (−0.85,0.01)). Naltrexone (SMD: -0.50; 95 %CI: (−0.85,-0.14)) and nalmefene (SMD: -0.36; 95 %CI: (−0.72,-0.01) were also more beneficial than placebo in terms of quality of life. Olanzapine and topiramate were not more efficacious than placebo. Nalmefene [Odds Ratio (OR): 7.55; 95 %CI: (2.24–25.41)] and naltrexone (OR: 7.82; 95 %CI: (1.26–48.70)) had significantly higher dropout due to side effects (lower tolerability) compared with placebo.

Interpretation

Based on NMA, nalmefene and naltrexone currently have the most supportive evidence for the pharmacological treatment of gambling disorder. Further clinical trials of novel compounds, and analysis of individual participant data are needed, to strengthen the evidence base, and help tailor treatments at the individual patient level.
背景:临床指南对治疗赌博障碍的药物的疗效和耐受性仍不明确。我们的目的是通过网络荟萃分析(NMA)比较药物治疗赌博障碍的疗效和耐受性:根据我们预先登记的方案[CRD42022329520],我们在广泛的数据库中进行了结构化检索,以寻找治疗赌博障碍药物的双盲随机对照试验(RCT)。数据由两名研究人员独立提取。我们使用Hedges'g标准化平均差(SMD)来衡量疗效结果,而对于耐受性的影响,我们使用因药物副作用而导致的辍学率(以几率比(OR)表示)。采用 CINeMA 框架评估了网络估计值的可信度。我们在这项工作中遵循了 PRISMA-NMA 指南。研究结果包括赌博症状严重程度、生活质量(疗效)和耐受性:我们在系统综述中纳入了 22 项 RCT,在 NMA 中纳入了 16 项 RCT(n = 977 名参与者)。与安慰剂相比,中等置信度的证据表明,纳美芬[标准化平均差(SMD):-0.86;95 %置信区间(CI):-1.32,-0.41]]可降低赌博的严重程度,其次是纳曲酮(SMD:-0.42;95 %CI:(-0.85,0.01))。就生活质量而言,纳曲酮(SMD:-0.50;95 %CI:(-0.85,-0.14))和纳美芬(SMD:-0.36;95 %CI:(-0.72,-0.01))也比安慰剂更有益。奥氮平和托吡酯的疗效并不优于安慰剂。与安慰剂相比,纳美芬[Odds Ratio (OR):7.55;95 %CI:(2.24-25.41)]和纳曲酮(OR:7.82;95 %CI:(1.26-48.70))因副作用(耐受性较低)而退出治疗的比例明显更高:根据NMA,纳美芬和纳曲酮目前在药物治疗赌博障碍方面拥有最有力的支持性证据。还需要对新型化合物进行进一步的临床试验,并对个体参与者的数据进行分析,以加强证据基础,并帮助根据患者的具体情况量身定制治疗方案。
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引用次数: 0
Longitudinal relationship between internet addiction and psychotic-like experiences among Chinese college students 中国大学生网络成瘾与类精神体验的纵向关系
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-01 DOI: 10.1016/j.comppsych.2024.152572
Pu Peng , Hongyu Zou

Background

While previous cross-sectional studies have suggested a link between psychotic-like experiences (PLEs) and internet addiction (IA), longitudinal evidence remains scarce. This study aimed to explore the prospective relationship between IA and PLEs among college students.

Method

A total of 636 college students (80 % female) were assessed in November 2022 and again one year later. IA was measured using the Internet Addiction Diagnosis Questionnaire (IADQ), and PLEs were assessed with the 16-item Prodromal Questionnaire (PQ-16). Demographic, psychological, and environmental factors were collected and controlled. Multiple logistic regression and cross-lagged panel analyses examined the longitudinal associations between IA and PLEs.

Results

At baseline, the prevalence of IA and PLEs was 11.3 % and 16.8 %, respectively. Higher baseline IADQ scores (Adjusted odds ratio = 1.035; 95 % confidence interval = 1.002–1.069; p = 0.036) were independently associated with an increased risk of PLEs at follow-up, while baseline PQ-16 scores were not linked to later IA. Cross-lagged panel analysis revealed that IA at baseline predicted later PLEs (β = 0.082, p = 0.043), whereas baseline PLEs did not predict IA (β = 0.049, p = 0.255). Specifically, IA predicted unusual thoughts (β = 0.122, p = 0.003) and negative PLEs (β = 0.111, p = 0.008), but not perceptual abnormalities (β = 0.040, p = 0.301).

Conclusion

IA may be an independent risk factor for PLEs in college students, particularly for unusual thoughts and negative PLEs, but not for perceptual abnormalities. Targeted interventions addressing IA may help reduce PLEs.
背景:虽然以前的横断面研究表明类精神体验(PLEs)和网络成瘾(IA)之间存在联系,但纵向证据仍然很少。本研究旨在探讨大学生主观幸福感与主观幸福感之间的潜在关系。方法:于2022年11月和一年后对636名大学生(80%为女性)进行评估。IA采用网络成瘾诊断问卷(IADQ)测量,ple采用16项前驱症状问卷(PQ-16)评估。收集和控制人口、心理和环境因素。多重逻辑回归和交叉滞后面板分析检验了IA和PLEs之间的纵向关联。结果:基线时,IA和PLEs的患病率分别为11.3%和16.8%。较高的基线IADQ评分(调整优势比= 1.035;95%置信区间= 1.002-1.069;p = 0.036)与随访时ple风险增加独立相关,而基线PQ-16评分与后来的IA无关。交叉滞后面板分析显示,基线时的IA预测后来的ple (β = 0.082, p = 0.043),而基线时的ple不能预测IA (β = 0.049, p = 0.255)。具体来说,IA预测异常思维(β = 0.122, p = 0.003)和负PLEs (β = 0.111, p = 0.008),但不预测感知异常(β = 0.040, p = 0.301)。结论:IA可能是大学生ple的独立危险因素,特别是异常思维和负ple,而不是知觉异常。针对IA的有针对性的干预措施可能有助于减少PLEs。
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引用次数: 0
Corrigendum to “An investigation into symptoms of depression and anxiety and emotion regulation among older adolescents from low-income settings in South Africa” [Journal Title volume (year) Start page–End page/Article Number: Comprehensive Psychiatry Volume 132, July 2024, 152476]
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-31 DOI: 10.1016/j.comppsych.2025.152577
C. Ward-Smith, K. Sorsdahl, C. van der Westhuizen
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引用次数: 0
Sharing knowledge on implementing mental health and wellbeing projects for veterans and first responders
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-27 DOI: 10.1016/j.comppsych.2025.152579
Cindy Woods, Sally Fitzpatrick, Sue Lukersmith

Purpose

The aim of this study was to describe the knowledge to action and knowledge transfer approaches used in an international mental health research funding program and its outcomes. A key goal of the evaluation was to maximise organisational learning and knowledge sharing to inform future implementation projects.

Methods

A series of interactive knowledge sharing workshops focused on five key themes: peer support; psychoeducation; the involvement of family, friends, and significant others; retreat, residential, or group-based programs; and organisational change. Qualitative descriptive analysis was used to code, summarise and describe themes.

Findings

Key learnings that influenced the success of mental health initiatives include building relationships across all organisational levels, involving Veterans and First Responders with lived experience in the design and implementation process, and understanding the unique workplace culture and operations.

Conclusion

Our findings highlight the need for collaborative, informed approaches tailored to the culture, organisation and mental health support needs of Veteran and First Responder. These insights enhance understanding of the factors that impact the successful implementation of mental health prevention and support programs for those exposed to work-related trauma.
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引用次数: 0
An ecosystem approach to the evaluation and impact analysis of heterogeneous preventive and/or early interventions projects for veterans and first responders in seven countries
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-25 DOI: 10.1016/j.comppsych.2025.152578
S. Lukersmith , L. Salvador-Carulla , C. Woods , T. Niyonsenga , M.R. Gutierrez-Colosia , I. Mohanty , C.R. Garcia-Alonso , D. Diaz-Milanes , J.A. Salinas-Perez , R. Davey , A. Aryani

Background

Cumulative exposure to critical incidents and life-threatening events leads to significant risk for Veterans and First Responders (VFRs) developing mental ill health and disorders. Philanthropic organisations, Movember and Distinguished Gentleman's Ride, funded 15 organisations to conduct early intervention Projects across seven countries. The Projects aim to improve the mental health and wellbeing of VFRs, their families/significant others. This paper describes the novel external evaluation and impact analysis methods to identify effective Projects having positive impact on VFRs and their families, provide return on investment and the overall Grant Program.

Methods

We take an ecosystem real-world approach, which recognises the context and aims to manage the complexities involved, uses a complexity and systems perspective, multi-step mixed methods and approaches. The evaluation is from three perspectives of: Projects; Project comparisons; Grant program. Embedded in the evaluation design are methods, knowledge sharing and organisational learning activities for all stakeholders. Data is collected by the Projects and evaluation team on input, throughputs, and output indicators. Analysis tools include Global Impact Analytics Framework, multi-layered statistical analysis, performance evaluation using an efficient decision support approach, Project and Grant program social return on investment, visual linking and data connection platform and assessment of gendered lens approaches.

Implications

The complexity and heterogeneity of Projects implemented in the real world continues to present significant evaluation challenges and limitations for project leads, stakeholders, researchers and evaluators. Our ecosystem approach and novel evaluation methodology will reduce the uncertainty around real world implementation, provide key learnings for project stakeholders and more broadly implementation researchers.
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引用次数: 0
The clinical phenomenology of skin-picking disorder – Are there any obsessive-compulsive components?
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-19 DOI: 10.1016/j.comppsych.2025.152575
Anne Schienle

Background

Skin-picking disorder (SPD) is currently conceptualized as a condition related to obsessive-compulsive disorder (OCD). The present study investigated whether the emotional, cognitive, and somatic components of skin-picking episodes align with this conceptual framework.

Method

A total of 134 patients diagnosed with SPD (mean age = 32 years; 84 % female; average symptom duration: 16 years) underwent in-person clinical assessment. Patients were asked to describe what they experienced directly before, during, and after picking their skin.

Results

Patients reported a very strong urge to manipulate their skin, particularly in situations characterized by emotional and/or bodily tension. No obsession-like phenomena preceded the skin-picking episodes. Skin manipulation had an immediately rewarding effect in the majority of patients or induced ‘trance-like’ states. After terminating a skin-picking episode, negative self-conscious emotions were dominant.

Conclusions

The interview findings do not align with the conceptualization of SPD as an OCD-related disorder. Patients reported no obsession-like symptoms, and their skin-picking behaviors did not serve harm prevention, which is characteristic of compulsions. Instead, the rewarding nature of skin-picking and its function in experiential avoidance suggests an addiction component to this behavior.
{"title":"The clinical phenomenology of skin-picking disorder – Are there any obsessive-compulsive components?","authors":"Anne Schienle","doi":"10.1016/j.comppsych.2025.152575","DOIUrl":"10.1016/j.comppsych.2025.152575","url":null,"abstract":"<div><h3>Background</h3><div>Skin-picking disorder (SPD) is currently conceptualized as a condition related to obsessive-compulsive disorder (OCD). The present study investigated whether the emotional, cognitive, and somatic components of skin-picking episodes align with this conceptual framework.</div></div><div><h3>Method</h3><div>A total of 134 patients diagnosed with SPD (mean age = 32 years; 84 % female; average symptom duration: 16 years) underwent in-person clinical assessment. Patients were asked to describe what they experienced directly before, during, and after picking their skin.</div></div><div><h3>Results</h3><div>Patients reported a very strong urge to manipulate their skin, particularly in situations characterized by emotional and/or bodily tension. No obsession-like phenomena preceded the skin-picking episodes. Skin manipulation had an immediately rewarding effect in the majority of patients or induced ‘trance-like’ states. After terminating a skin-picking episode, negative self-conscious emotions were dominant.</div></div><div><h3>Conclusions</h3><div>The interview findings do not align with the conceptualization of SPD as an OCD-related disorder. Patients reported no obsession-like symptoms, and their skin-picking behaviors did not serve harm prevention, which is characteristic of compulsions. Instead, the rewarding nature of skin-picking and its function in experiential avoidance suggests an addiction component to this behavior.</div></div>","PeriodicalId":10554,"journal":{"name":"Comprehensive psychiatry","volume":"138 ","pages":"Article 152575"},"PeriodicalIF":4.3,"publicationDate":"2025-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Comprehensive psychiatry
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