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Loneliness and the emergence of problematic online behaviours in young adults: A cross-lagged panel network analysis 孤独感与年轻人网络问题行为的出现:一个交叉滞后的面板网络分析。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-11-16 DOI: 10.1016/j.comppsych.2025.152646
Marta Błoch, Błażej Misiak

Background

Loneliness is a public health priority due to its high prevalence and impact on various health outcomes. It might be associated with problematic internet use that is highly prevalent in young adults. However, its associations with specific problematic online behaviours (POBs) at their early stages of development remains unknown. The present study explored longitudinal associations between loneliness and various POBs in a general population sample of young adults without a history of psychiatric treatment.

Methods

Altogether, 1441 individuals were assessed at baseline (aged 29.5 ± 6.3 years, 51.4 % women). The follow-up assessment was scheduled after 6 months and was completed by 733 individuals (aged 30.5 ± 6.0 years, 49.1 % women, retention rate of 50.9 %). The data were collected using self-reports and analyzed using a cross-lagged panel network model.

Results

Higher baseline levels of loneliness predicted higher levels of problematic cybersex, depressive symptoms, and anxiety symptoms at the follow-up. In turn, higher levels of loneliness were predicted by higher baseline levels of problematic online gaming, cyberchondria, and depressive symptoms. The highest output centrality was found for problematic online gaming and shopping. Loneliness was ranked among the nodes with the lowest output centrality in the network. However, it showed the highest auto-regressive effect suggesting its high stability over time.

Conclusions

The findings indicate that loneliness is bidirectionally associated with POBs with problematic online gaming, cyberchondria, and cybersex playing the most important roles in these associations. These observations indicate the necessity to consider loneliness among therapeutic targets among individuals with POBs.
背景:由于孤独的高患病率和对各种健康结果的影响,它是一个公共卫生重点。这可能与年轻人中普遍存在的上网问题有关。然而,它与早期发展阶段的特定问题在线行为(pob)的关联仍然未知。本研究在没有精神治疗史的年轻成年人的一般人群样本中探讨了孤独感和各种pob之间的纵向联系。方法:共有1441人在基线时接受评估(年龄29.5±6.3岁,51.4%为女性)。随访时间为6个月,733人(年龄30.5±6.0岁,女性49.1%,保留率50.9%)完成随访评估。通过自我报告收集数据,并使用交叉滞后面板网络模型进行分析。结果:孤独感的基线水平越高,预示着在随访中有问题的网络性行为、抑郁症状和焦虑症状的水平越高。反过来,高水平的孤独感与高水平的网络游戏问题、网络疑病症和抑郁症状的基线水平有关。问题在线游戏和购物的输出中心性最高。孤独感是网络中输出中心性最低的节点之一。然而,它显示出最高的自回归效应,表明其随着时间的推移具有很高的稳定性。结论:研究结果表明,孤独感与pob呈双向关系,其中网络游戏、网络疑病和网络性行为在这些关系中起着最重要的作用。这些观察结果表明,有必要在pob患者的治疗目标中考虑孤独感。
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引用次数: 0
Trichotillomania, skin picking disorder, and pregnancy 拔毛癖,抠皮障碍,还有怀孕。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-11-16 DOI: 10.1016/j.comppsych.2025.152647
Jon E. Grant , Megha Neelapu , Laurie Avila , Sophia Boutouis , Samuel R. Chamberlain

Background

Trichotillomania (hair pulling disorder) and skin picking disorder have typical age of onset around puberty, and appear more common in women than in men, suggesting the possibility that hormonal systems may relate to symptoms. Yet virtually no research has explored relationships between pregnancy (and the post-partum period) and symptom severity in people affected by these conditions.

Methods

People with trichotillomania and/or skin picking disorder were recruited from the general community if they had previously experienced at least one pregnancy during their lifetimes. Data were collected regarding perceived relationships between symptom severity, pregnancy, and the post-partum period.

Results

Whilst some women reported an exacerbation of hair pulling and/or skin picking during pregnancy or in the perinatal period, the majority of women reported no change or even reductions in such symptoms during these times.

Conclusions

These data suggest that relationships between pregnancy and hair pulling plus skin picking symptoms can vary depending on the individual. Future work could examine these relationships at the time of pregnancy and afterwards, rather than using retrospective questionnaires; and could also collect biological measures to help explore any underlying mechanisms that may account for this variation in symptoms.
背景:拔毛癖(拔毛障碍)和抠皮障碍的典型发病年龄在青春期左右,女性比男性更常见,提示激素系统可能与症状有关。然而,几乎没有研究探索怀孕(和产后期)与这些疾病患者的症状严重程度之间的关系。方法:从一般社区招募有拔毛癖和/或抠皮障碍的人,如果他们在一生中至少经历过一次怀孕。收集有关症状严重程度、妊娠和产后期之间关系的数据。结果:虽然一些妇女报告在怀孕期间或围产期拔毛和/或抠皮加剧,但大多数妇女报告在此期间这些症状没有变化甚至减轻。结论:这些数据表明妊娠与拔毛和抠皮症状之间的关系因人而异。未来的工作可以在怀孕期间和之后检查这些关系,而不是使用回顾性问卷;还可以收集生物学指标,以帮助探索可能导致这种症状变化的潜在机制。
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引用次数: 0
Genetic and clinical characteristics associated with antidepressant-induced mania in depression patients 抑郁症患者抗抑郁药诱发躁狂症的遗传和临床特征
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-11-16 DOI: 10.1016/j.comppsych.2025.152648
Shiau-Shian Huang , Ying-Ting Chao , Yu-Ning Chen , Mei-Hsin Su , Chiao-Erh Chang , Shih-Jen Tsai , Po-Hsiu Kuo

Introduction

Antidepressant-induced mania (AIM) is a significant clinical concern, primarily studied in bipolar disorder patients. Limited research exists on AIM in unipolar depression, with reported incidence rates of 3.0–8.2 %.

Methods

Using data from the Taiwan's National Health Insurance Research Database merged with Taiwan Biobank (2001–2017), we analyzed 772 depression patients who were prescribed antidepressants and had available genotype data. A genome-wide association study (GWAS) was performed to investigate potential genetic factors associated with AIM. Single-marker association analysis and polygenic risk scores were calculated using PLINK.

Results

AIM developed in 145 (19.65 %) of depressive patients within 28 days of medication use or discontinuation. Significant associated clinical characteristics included female gender, postpartum depression, comorbid obsessive-compulsive disorder, severe depression, substance use disorders, and other non-organic psychosis. Eight single nucleotide polymorphisms were identified as potential genetic markers associated with AIM in this GWAS, and higher polygenic risk scores for bipolar disorder were associated with increased AIM risk.

Conclusion

AIM was observed in one-fifth of depressive patients of the Han Chinese origin, with female gender and psychiatric comorbidities as significant clinical characteristics. This GWAS of AIM in depressive patients identified potential genetic markers and suggested that a genetic predisposition to bipolar disorder may increase the likelihood of developing AIM, although this association did not reach statistical significance. Future research should aim to increase sample size and further investigate genotype-AIM associations.
抗抑郁药诱发的躁狂症(AIM)是一个重要的临床问题,主要在双相情感障碍患者中进行研究。关于AIM在单极抑郁症中的研究有限,据报道发病率为3.0 - 8.2%。方法利用台湾全民健康保险研究数据库和台湾生物库(2001-2017)的数据,分析772名服用抗抑郁药物并有基因型数据的抑郁症患者。进行全基因组关联研究(GWAS)以调查与AIM相关的潜在遗传因素。使用PLINK计算单标记关联分析和多基因风险评分。结果145例(19.65%)抑郁患者在用药或停药28 d内发生aim。显著的相关临床特征包括女性、产后抑郁、共病强迫症、重度抑郁症、物质使用障碍和其他非器质性精神病。在该GWAS中,8个单核苷酸多态性被确定为与AIM相关的潜在遗传标记,双相情感障碍的高多基因风险评分与AIM风险增加相关。结论汉族抑郁症患者中有1 / 5存在aim,以女性和精神合并症为显著临床特征。抑郁症患者AIM的GWAS发现了潜在的遗传标记,表明双相情感障碍的遗传易感性可能增加患AIM的可能性,尽管这种关联没有达到统计学意义。未来的研究应致力于增加样本量,并进一步研究基因型与aim的关联。
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引用次数: 0
A remotely-applied, cognitive control-based video game intervention to reduce depressive symptoms in a sub-clinical population: A randomized controlled trial (RCT) 远程应用,基于认知控制的视频游戏干预减少亚临床人群的抑郁症状:一项随机对照试验(RCT)。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-10-30 DOI: 10.1016/j.comppsych.2025.152645
Noa Givon Schacham , Angela Pasqualotto , Naamah Lerner , Marios Fanourakis , Zeno Menestrina , Daphne Bavelier , Mor Nahum
Depressive symptoms are prevalent among young adults, with cognitive theories suggesting that impaired cognitive control contributes to sustained negative mood and depressive symptoms. This study investigated the feasibility and efficacy of a remotely-applied, tablet-based cognitive control video game, Legends of Hoa'manu (LoH), for reducing depressive symptoms in subclinical adults.
A randomized controlled trial (NCT05447091) was conducted with 173 participants (mean age 33 ± 11.6 years; 75.1 % female) exhibiting at least a minimal level of depressive symptoms (PHQ-8 ≥ 5). Participants were randomized into three groups: high-dose experimental game (HD_EG; N = 58), low-dose experimental game (LD_EG; N = 61), and high-dose control game (HD_CG; N = 54), with interventions spanning three weeks.
The intervention demonstrated high feasibility and adherence (69.5–76.5 % of sessions completed) without direct study contact. Overall depressive symptoms (BDI-II total score) improved across all groups, with a significant main effect of time, but no significant group differences. Still, group differences were found for the cognitive-affective BDI-II subscale, where the HD_EG group showed the largest reduction (4.5 points vs. 2.3 and 2.1 in the LD_EG and HD_CG, respectively). These improvements were maintained at 3-week and 3-month follow-ups. Secondary outcomes, including anxiety and rumination, also improved across all groups. Overall cognitive control performance did not differ between groups; however, significant improvements in inhibitory control emerged exclusively in the HD_EG group.
The results highlight the feasibility of this novel, cost-effective, and remotely-applied cognitive control-based intervention. These findings underscore the potential of LoH as a scalable solution for addressing depressive symptoms in subclinical populations.
抑郁症状在年轻人中很普遍,认知理论表明认知控制受损会导致持续的负面情绪和抑郁症状。本研究调查了远程应用、基于平板电脑的认知控制视频游戏《Hoa’manu Legends》(LoH)减轻亚临床成人抑郁症状的可行性和有效性。一项随机对照试验(NCT05447091)对173名参与者(平均年龄33±11.6岁;75.1%为女性)进行了研究,这些参与者至少表现出最低程度的抑郁症状(PHQ-8≥5)。参与者被随机分为三组:高剂量实验游戏(HD_EG, N = 58)、低剂量实验游戏(LD_EG, N = 61)和高剂量控制游戏(HD_CG, N = 54),干预时间为三周。在没有直接研究接触的情况下,干预显示出很高的可行性和依从性(69.5- 76.5%的疗程完成)。总体抑郁症状(BDI-II总分)在所有组间均有改善,主要受时间影响,但组间无显著差异。然而,在认知情感BDI-II子量表上发现了组间差异,其中HD_EG组表现出最大的下降(4.5分,LD_EG和HD_CG分别为2.3和2.1分)。这些改善在3周和3个月的随访中保持不变。包括焦虑和反刍在内的次要结果在所有组中也有所改善。整体认知控制表现在两组之间没有差异;然而,抑制控制的显著改善仅出现在HD_EG组。结果强调了这种新颖、经济、远程应用的基于认知控制的干预措施的可行性。这些发现强调了LoH作为解决亚临床人群抑郁症状的可扩展解决方案的潜力。
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引用次数: 0
What goes around comes around? Holding racist attitudes predicts increased psychological distress over time 一报还一报?持有种族主义态度预示着随着时间的推移,心理压力会增加。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-10-30 DOI: 10.1016/j.comppsych.2025.152644
Tegan Cruwys , Olivia Evans , Michael J. Platow , Iain Walker , Katherine J. Reynolds , Christienne Javier , Catherine Haslam , S. Alexander Haslam , Hema Preya Selvanathan

Background

There has been a tendency for the academic literature, media, and practitioners to attribute prejudice — particularly extreme beliefs and the violence they can engender — to mental ill-health. Meta-analyses have found relationships (albeit weak) among these variables, but they rely primarily on correlational evidence. The reverse pathway, from holding prejudice to mental ill-health, has rarely been considered. Moreover, a third, unexplored, variable might cause both. To address these gaps, we investigate reciprocal relationships between holding racist beliefs – one form of prejudice – and mental ill-health over time. We further consider the possible operation of a third variable: social connectedness (or lack thereof, in the form of ostracism, alienation, etc).

Methods

The bidirectional link between racism and mental ill-health (operationalised as psychological distress) was assessed in three longitudinal Australian studies, each with over 2000 participants and three timepoints spanning approximately six months.

Results

The cross-sectional associations between racism and psychological distress were small and unreliable. However, longitudinally, an increase in racist beliefs consistently preceded and predicted increased psychological distress. Social connectedness strongly predicted less racism and less psychological distress.

Conclusions

These findings suggest that people who hold prejudiced beliefs are at increased risk of psychological distress over time. This challenges common claims that it is mental ill-health that leads to prejudiced beliefs. Implications are discussed with an emphasis on the potentially undervalued contribution of positive social connection as a counterforce to both prejudice and mental ill-health.
背景:学术文献、媒体和从业人员一直倾向于将偏见——特别是极端信仰和由此产生的暴力——归咎于精神疾病。荟萃分析发现了这些变量之间的关系(尽管很弱),但它们主要依赖于相关证据。相反的途径,从持有偏见到精神疾病,很少被考虑。此外,第三个未知的变量可能导致这两种情况。为了解决这些差距,我们调查了长期持有种族主义信仰(一种偏见)与精神疾病之间的相互关系。我们进一步考虑了第三个变量的可能运作:社会联系(或缺乏社会联系,以排斥、疏远等形式)。方法:在澳大利亚的三项纵向研究中评估了种族主义与精神疾病(作为心理困扰运作)之间的双向联系,每项研究都有2000多名参与者,三个时间点跨度约为6个月。结果:种族主义与心理困扰之间的横断面关联较小且不可靠。然而,从纵向上看,种族主义信仰的增加总是先于并预示着心理困扰的增加。社会联系强烈地预示着较少的种族主义和较少的心理困扰。结论:这些发现表明,持有偏见信仰的人随着时间的推移,心理困扰的风险会增加。这挑战了通常认为是精神不健康导致偏见信仰的说法。讨论的影响,重点是潜在低估的贡献积极的社会关系作为一个反作用力,偏见和精神疾病健康。
{"title":"What goes around comes around? Holding racist attitudes predicts increased psychological distress over time","authors":"Tegan Cruwys ,&nbsp;Olivia Evans ,&nbsp;Michael J. Platow ,&nbsp;Iain Walker ,&nbsp;Katherine J. Reynolds ,&nbsp;Christienne Javier ,&nbsp;Catherine Haslam ,&nbsp;S. Alexander Haslam ,&nbsp;Hema Preya Selvanathan","doi":"10.1016/j.comppsych.2025.152644","DOIUrl":"10.1016/j.comppsych.2025.152644","url":null,"abstract":"<div><h3>Background</h3><div>There has been a tendency for the academic literature, media, and practitioners to attribute prejudice — particularly extreme beliefs and the violence they can engender — to mental ill-health. Meta-analyses have found relationships (albeit weak) among these variables, but they rely primarily on correlational evidence. The reverse pathway, from holding prejudice to mental ill-health, has rarely been considered. Moreover, a third, unexplored, variable might cause both. To address these gaps, we investigate reciprocal relationships between holding racist beliefs – one form of prejudice – and mental ill-health over time. We further consider the possible operation of a third variable: social connectedness (or lack thereof, in the form of ostracism, alienation, etc).</div></div><div><h3>Methods</h3><div>The bidirectional link between racism and mental ill-health (operationalised as psychological distress) was assessed in three longitudinal Australian studies, each with over 2000 participants and three timepoints spanning approximately six months.</div></div><div><h3>Results</h3><div>The cross-sectional associations between racism and psychological distress were small and unreliable. However, longitudinally, an increase in racist beliefs consistently preceded and predicted increased psychological distress. Social connectedness strongly predicted less racism and less psychological distress.</div></div><div><h3>Conclusions</h3><div>These findings suggest that people who hold prejudiced beliefs are at increased risk of psychological distress over time. This challenges common claims that it is mental ill-health that leads to prejudiced beliefs. Implications are discussed with an emphasis on the potentially undervalued contribution of positive social connection as a counterforce to both prejudice and mental ill-health.</div></div>","PeriodicalId":10554,"journal":{"name":"Comprehensive psychiatry","volume":"144 ","pages":"Article 152644"},"PeriodicalIF":4.2,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145444334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptation, implementation, and evaluation of a protective mental health intervention (Resilient minds) for Canadian volunteer firefighters 加拿大志愿消防员保护性心理健康干预(弹性心理)的适应、实施和评估
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-10-24 DOI: 10.1016/j.comppsych.2025.152643
Joy C. MacDermid , Shannon C. Killip , Amanda Brazil , Margaret Lomotan , Steve Fraser , Dianne Bryant , Heidi Cramm , R. Nicholas Carleton

Purpose

The study was designed to assess the adaptation, implementation, and delivery of the Resilient Minds program for volunteer firefighters in Prince Edward Island.

Methods

A concurrent triangulation mixed-methods approach was used. Survey data were collected from firefighters who participated in the training, and semi-structured interviews were performed with peer trainers, members of leadership, and firefighters who participated in the implementation. Summary statistics were performed to summarize the survey data, and thematic analysis was performed to analyze the qualitative data following interpretive description methods. We followed the Consolidated Framework for Implementation Research to guide our data collection and analyses.

Results

The relative advantage of Resilient Minds (i.e., created for firefighters) and the high-priority need for mental health training promoted buy-in from stakeholders and facilitated program implementation. Most participants described the training as helpful (84 %), and reported high intention to use the information (86 %). At three-month follow-up, most reported being able to recall the training (83 %), and reported increased support from colleagues (59 %) and leadership (50 %). Our qualitative data identified improvements in coping and awareness of mental health issues, and decreases in mental health stigma. Suggestions were provided to improve the adaptation and implementation (e.g., simplifying the content, obtaining funding).

Conclusion

Our results support the adaptation, implementation, and delivery of Resilient Minds among Canadian volunteer firefighters. Scaled delivery of the training across Canada will require collaborations among the developers, local implementation leads, and other stakeholders in the local fire services to adapt the course content and implementation procedures for the needs of each fire department.
目的本研究旨在评估爱德华王子岛志愿消防员弹性思维项目的适应、实施和交付情况。方法采用并行三角剖分混合方法。从参加培训的消防员中收集调查数据,并与同行培训师、领导成员和参与实施的消防员进行半结构化访谈。对调查数据进行汇总统计,对定性数据进行专题分析,采用解释性描述方法。我们遵循《实施研究综合框架》来指导我们的数据收集和分析。结果弹性心理(即为消防员创建)的相对优势和对心理健康培训的高度优先需求促进了利益相关者的购买,并促进了计划的实施。大多数参与者认为培训是有帮助的(84%),并报告了使用这些信息的高意图(86%)。在三个月的随访中,大多数人报告说能够回忆起培训(83%),并报告说同事(59%)和领导(50%)的支持增加了。我们的定性数据表明,心理健康问题的应对和意识有所改善,心理健康耻辱感有所减少。提出了改进改编和执行的建议(例如,简化内容、获得资金)。结论:我们的研究结果支持加拿大志愿消防员弹性思维的适应、实施和交付。在加拿大各地大规模交付培训将需要开发人员、当地实施领导和当地消防部门的其他利益相关者之间的合作,以适应每个消防部门的需求,调整课程内容和实施程序。
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引用次数: 0
HUGS@Home - An initial evaluation of a psychological first aid programme for families and friends of first responders HUGS@Home -对急救人员的家人和朋友的心理急救方案的初步评估。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-10-10 DOI: 10.1016/j.comppsych.2025.152636
Michelle O'Toole , Brian Doyle , Walter Eppich , Brett Williams , Alan M. Batt

Background

First responders such as paramedics and firefighters increasingly rely on their family and friends for psychosocial support due to workplace barriers such as culture and stigma. Despite many benefits, such support is often perceived as placing a burden on family and friends. The ability to provide Psychological First Aid (PFA) has not yet been explored in the context of family members and friends providing support to first responders. In this study, we explored the impacts of PFA on first responders and family members/friends.

Methods

This pre-post study design was informed by a wider programme of research adopting a Community Based Participatory Research approach. We co-designed a simulation enhanced PFA training intervention -the HUGS@Home programme. We collected survey data over three time points from family member/friend participants and their corresponding first responders. We analysed the data using descriptive and comparative statistical analysis. External evaluation of the intervention occurred simultaneously.

Findings

Ten family member/friend cohorts (n = 82) completed the training in Ireland and the United Kingdom. Results indicate they experienced increased quality of life, improved social support, maintenance of high resilience scores, a slight increase in anxiety levels and most notably, enhanced post traumatic growth. Their related first responders (n = 33) noted similar results, in addition to demonstrating improved help-seeking and post-traumatic growth, specifically in the ‘improved relationships’ subdomain. Both groups found the intervention significant, meaningful, and valuable. External evaluation considered the programme mature and ready for wider implementation.

Conclusions

HUGS@Home contributes significantly to the international PFA evidence base as the first evaluation of a PFA intervention in Ireland. This is the first study to demonstrate that family members and friends can effectively provide PFA to first responders. Further planned and ongoing work will explore our findings in detail and evaluate programme implementation in volunteer first responder populations.
背景:由于文化和污名等工作场所障碍,护理人员和消防员等急救人员越来越依赖家人和朋友的社会心理支持。尽管有很多好处,但这种支持往往被视为给家人和朋友带来负担。提供心理急救(PFA)的能力尚未在家庭成员和朋友向急救人员提供支持的背景下进行探索。在本研究中,我们探讨了PFA对急救人员和家庭成员/朋友的影响。方法:采用基于社区的参与性研究方法,通过更广泛的研究项目来了解这种前后研究设计。我们共同设计了一个模拟增强PFA培训干预- HUGS@Home计划。我们从家庭成员/朋友参与者和他们相应的第一响应者中收集了三个时间点的调查数据。我们使用描述性和比较统计分析来分析数据。干预措施的外部评估同时进行。研究结果:10个家庭成员/朋友队列(n = 82)在爱尔兰和英国完成了培训。结果表明,他们的生活质量得到了提高,社会支持得到了改善,恢复力得分保持在较高水平,焦虑水平略有提高,最值得注意的是,创伤后成长得到了提高。他们相关的第一响应者(n = 33)也注意到类似的结果,除了表明寻求帮助和创伤后成长有所改善,特别是在“改善的关系”子领域。两组人都认为干预是重要的、有意义的和有价值的。外部评价认为该方案已经成熟,可以更广泛地执行。结论:HUGS@Home作为爱尔兰PFA干预的首次评估,为国际PFA证据基础做出了重大贡献。这是第一个证明家庭成员和朋友可以有效地向急救人员提供PFA的研究。进一步计划和正在进行的工作将详细探讨我们的发现,并评估志愿第一响应者群体中的方案实施情况。
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引用次数: 0
Approach tendencies towards pornographic material in compulsive sexual behavior disorder: insights from the sex@brain study 强迫性性行为障碍中色情倾向的探讨:来自sex@brain研究的见解。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-10-06 DOI: 10.1016/j.comppsych.2025.152640
Jannis Engel , Maria Veit , Laura Budnik , Stephanie Antons , Christopher Sinke , Tillmann H.C. Kruger

Background

Compulsive Sexual Behavior Disorder (CSBD) is a new category in the 11th version of the International Classification of Diseases and has neuropsychological similarities with those disorders due to addictive behaviors. Initial automatic approach tendencies and an attentional bias towards preferred stimuli may be crucial to the maintenance of addictive behavior disorders.

Aims

This experimental study aims to further our knowledge on approach-avoidance tendencies by examining a clinical sample with compulsive sexual behavior CSBD compared to a control-group.

Methods

Participants completed the approach avoidance task (AAT) modified with pornographic pictures.

Outcomes

We collected data on approach-avoidance tendencies from 43 heterosexual men with CSBD (age, M = 36.26, SD = 11.47) and a control group of 37 men without CSBD (age: M = 38.24, SD = 12.33).

Results

Reaction times of the onset of cue presentation to initial hand movement show significantly more approach tendencies towards pornographic stimuli in men with CSBD vs. men without CSBD. Negative values of movement times (MT) suggested longer viewing times when enlarging the stimulus compared to shrinking the image for pornographic and neutral material with a larger difference in the CSBD group. The overall effect scores for RT show a faster reaction time in men without CSBD towards pornographic material, while the MT scores indicates that men with CSBD show longer viewing times for pornographic material.

Conclusion

Our results emphasize previous findings in subclinical samples and show that CSBD is associated with approach tendencies at the time of stimulus presentation. These approach tendencies can be addressed therapeutically.
背景:强迫性性行为障碍(CSBD)是《国际疾病分类》(International Classification of Diseases)第11版新增的一类疾病,与成瘾行为引起的障碍具有神经心理学上的相似性。最初的自动接近倾向和对偏好刺激的注意偏差可能对成瘾行为障碍的维持至关重要。目的:本实验研究旨在通过检查强迫性性行为CSBD的临床样本与对照组进行比较,进一步了解我们对方法回避倾向的了解。方法:被试完成带有色情图片的避近任务(AAT)。结果:我们收集了43名患有CSBD的异性恋男性(年龄,M = 36.26, SD = 11.47)和37名非CSBD男性(年龄:M = 38.24, SD = 12.33)的趋近回避倾向数据。结果:提示出现到初始手部运动的反应时间显示,CSBD男性比非CSBD男性更倾向于色情刺激。运动时间(MT)为负值时,放大刺激比缩小色情和中性材料时观看时间更长,CSBD组差异更大。RT的总体效果得分表明,没有CSBD的男性对色情材料的反应时间更快,而MT得分表明,有CSBD的男性对色情材料的观看时间更长。结论:我们的研究结果强调了先前在亚临床样本中的发现,表明CSBD与刺激呈现时的趋近倾向有关。这些方法倾向可以通过治疗来解决。
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引用次数: 0
The role of HAART in mitigating neurocognitive decline among HIV-positive Africans: Systematic review and meta-analysis HAART在缓解非洲hiv阳性患者神经认知能力下降中的作用:系统回顾和荟萃分析
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-10-06 DOI: 10.1016/j.comppsych.2025.152639
Mulualem Kelebie , Getasew Kibralew , Gebresilassie Tadesse , Girum Nakie , Mulu Muche , Dawed Ali , Birtukan Fasil , Gidey Rtbey , Biruk Fanta , Nega Gedefaw Agmase , Girmaw Medfu Takelle , Melese Gobezie , Mequanente Dagnaw , Setegn Fentahun

Background

HIV-associated neurocognitive disorders (HAND) remain a significant public health concern among people living with HIV (PWH) in Africa, despite the widespread implementation of highly active antiretroviral therapy (HAART). While HAART has been effective in reducing the incidence of severe neurocognitive disorder, milder forms of neurocognitive impairment continue to be observed even among individuals receiving active antiretroviral therapy. These subtle deficits, particularly prevalent in low-resource and low-literacy contexts, are associated with adverse outcomes such as diminished functional capacity, poor adherence to antiretroviral therapy, and reduced quality of life. This systematic review and meta-analysis aims to synthesize the current evidence on the effectiveness of HAART on neurocognitive outcomes among HIV-positive individuals in Africa.

Methods

A comprehensive systematic search was conducted across multiple electronic databases—including PubMed/MEDLINE, Scopus, African Journals Online, PsycINFO, EMBASE, CINAHL, and the Cochrane Library—to identify primary research studies that examined the prevalence and clinical impact of HIV-associated neurocognitive disorders (HAND) among HIV-infected populations in Africa. Study selection and data extraction were performed independently by two reviewers using predefined standardized protocols to ensure methodological rigor and minimize the risk of bias. The review protocol was prospectively registered with PROSPERO (CRD420251017353).

Results

This meta-analysis, which included 62 primary studies with a combined sample of 19,831 individuals living with HIV, estimated a pooled prevalence of HIV-associated neurocognitive disorders was 47.18% (95% CI: 39.94%–54.42%). In contrast, among 2,176 HIV-negative individuals in the control group, the prevalence of neurocognitive disorder was 13.48% (95% CI: 10.9%–15.32%). Sub-regional stratification revealed the highest HAND prevalence in Eastern Africa (50.85%), followed by Southern Africa (48.12%) and Western Africa (43.67%), while Central Africa reported the lowest prevalence at 34.68%. Among individuals receiving antiretroviral therapy (ART), the prevalence of HAND was 46.96%, compared to 50.22% in ART-naïve participants, indicating only a modest reduction in neurocognitive impairment associated with ART exposure. Meta-regression analyses identified several independent predictors significantly associated with increased odds of HAND, including advanced HIV disease stage (odds ratio [OR] 3.59; 95% CI: 2.81–4.59), lower educational attainment (3.13, 2.19–4.48), older age (2.05, 1.51–2.78), being female (2.18, 1.79-2.64), history of substance use (2.70, 2.65–2.75), reduced CD4+ T-cell counts (2.49, 1.42–4.36) and comorbid medical illness (2.05, 1.57-2.67).

Conclusion

HIV-associated neurocognitive disorders affect nearly half of people living with
背景:尽管高效抗逆转录病毒疗法(HAART)在非洲广泛实施,但艾滋病毒相关神经认知障碍(HAND)仍然是艾滋病毒感染者(PWH)中一个重要的公共卫生问题。虽然HAART在减少严重神经认知障碍发生率方面有效,但即使在接受积极抗逆转录病毒治疗的个体中,仍可观察到轻度形式的神经认知障碍。这些细微的缺陷,特别是在资源匮乏和识字率低的环境中普遍存在,与功能能力下降、抗逆转录病毒治疗依从性差和生活质量下降等不良后果有关。本系统综述和荟萃分析旨在综合目前关于HAART对非洲hiv阳性个体神经认知结果有效性的证据。方法对多个电子数据库(包括PubMed/MEDLINE、Scopus、African Journals Online、PsycINFO、EMBASE、CINAHL和Cochrane library)进行了全面的系统检索,以确定在非洲hiv感染人群中检测hiv相关神经认知障碍(HAND)患病率和临床影响的主要研究。研究选择和数据提取由两位审稿人独立完成,采用预定义的标准化方案,以确保方法的严谨性并将偏倚风险降至最低。该审查方案在PROSPERO进行了前瞻性注册(CRD420251017353)。该荟萃分析包括62项主要研究,共19831名HIV感染者,估计HIV相关神经认知障碍的总患病率为47.18% (95% CI: 39.94%-54.42%)。相反,在对照组的2176名hiv阴性个体中,神经认知障碍的患病率为13.48% (95% CI: 10.9%-15.32%)。分区域分层显示,东部非洲的HAND患病率最高(50.85%),其次是南部非洲(48.12%)和西部非洲(43.67%),中部非洲最低(34.68%)。在接受抗逆转录病毒治疗(ART)的个体中,HAND的患病率为46.96%,而ART-naïve参与者的患病率为50.22%,这表明与ART暴露相关的神经认知障碍仅略有减少。meta回归分析确定了几个与HAND发病率增加显著相关的独立预测因素,包括HIV疾病阶段晚期(比值比[OR] 3.59; 95% CI: 2.81-4.59)、受教育程度较低(3.13,2.19-4.48)、年龄较大(2.05,1.51-2.78)、女性(2.18,1.79-2.64)、药物使用史(2.70,2.65-2.75)、CD4+ t细胞计数降低(2.49,1.42-4.36)和共病性疾病(2.05,1.57-2.67)。结论:尽管HAART在非洲得到广泛应用,但艾滋病毒相关神经认知障碍影响了近一半的艾滋病毒感染者,这凸显了艾滋病毒护理方面的严重需求未得到满足。虽然高效抗逆转录病毒疗法减少了严重的认知障碍,但它对较轻但致残的形式提供的保护有限,特别是在社会经济上处于不利地位和识字率低的人群中。造成这种情况的因素包括疾病晚期、受教育程度低、老龄化、女性、药物使用、免疫抑制和其他慢性疾病。将定期认知评估、及时干预和文化上适宜的康复纳入艾滋病毒护理对于提高临床结果和生活质量至关重要。
{"title":"The role of HAART in mitigating neurocognitive decline among HIV-positive Africans: Systematic review and meta-analysis","authors":"Mulualem Kelebie ,&nbsp;Getasew Kibralew ,&nbsp;Gebresilassie Tadesse ,&nbsp;Girum Nakie ,&nbsp;Mulu Muche ,&nbsp;Dawed Ali ,&nbsp;Birtukan Fasil ,&nbsp;Gidey Rtbey ,&nbsp;Biruk Fanta ,&nbsp;Nega Gedefaw Agmase ,&nbsp;Girmaw Medfu Takelle ,&nbsp;Melese Gobezie ,&nbsp;Mequanente Dagnaw ,&nbsp;Setegn Fentahun","doi":"10.1016/j.comppsych.2025.152639","DOIUrl":"10.1016/j.comppsych.2025.152639","url":null,"abstract":"<div><h3>Background</h3><div>HIV-associated neurocognitive disorders (HAND) remain a significant public health concern among people living with HIV (PWH) in Africa, despite the widespread implementation of highly active antiretroviral therapy (HAART). While HAART has been effective in reducing the incidence of severe neurocognitive disorder, milder forms of neurocognitive impairment continue to be observed even among individuals receiving active antiretroviral therapy. These subtle deficits, particularly prevalent in low-resource and low-literacy contexts, are associated with adverse outcomes such as diminished functional capacity, poor adherence to antiretroviral therapy, and reduced quality of life. This systematic review and meta-analysis aims to synthesize the current evidence on the effectiveness of HAART on neurocognitive outcomes among HIV-positive individuals in Africa.</div></div><div><h3>Methods</h3><div>A comprehensive systematic search was conducted across multiple electronic databases—including PubMed/MEDLINE, Scopus, African Journals Online, PsycINFO, EMBASE, CINAHL, and the Cochrane Library—to identify primary research studies that examined the prevalence and clinical impact of HIV-associated neurocognitive disorders (HAND) among HIV-infected populations in Africa. Study selection and data extraction were performed independently by two reviewers using predefined standardized protocols to ensure methodological rigor and minimize the risk of bias. The review protocol was prospectively registered with PROSPERO (CRD420251017353).</div></div><div><h3>Results</h3><div>This meta-analysis, which included 62 primary studies with a combined sample of 19,831 individuals living with HIV, estimated a pooled prevalence of HIV-associated neurocognitive disorders was 47.18% (95% CI: 39.94%–54.42%). In contrast, among 2,176 HIV-negative individuals in the control group, the prevalence of neurocognitive disorder was 13.48% (95% CI: 10.9%–15.32%). Sub-regional stratification revealed the highest HAND prevalence in Eastern Africa (50.85%), followed by Southern Africa (48.12%) and Western Africa (43.67%), while Central Africa reported the lowest prevalence at 34.68%. Among individuals receiving antiretroviral therapy (ART), the prevalence of HAND was 46.96%, compared to 50.22% in ART-naïve participants, indicating only a modest reduction in neurocognitive impairment associated with ART exposure. Meta-regression analyses identified several independent predictors significantly associated with increased odds of HAND, including advanced HIV disease stage (odds ratio [OR] 3.59; 95% CI: 2.81–4.59), lower educational attainment (3.13, 2.19–4.48), older age (2.05, 1.51–2.78), being female (2.18, 1.79-2.64), history of substance use (2.70, 2.65–2.75), reduced CD4+ T-cell counts (2.49, 1.42–4.36) and comorbid medical illness (2.05, 1.57-2.67).</div></div><div><h3>Conclusion</h3><div>HIV-associated neurocognitive disorders affect nearly half of people living with","PeriodicalId":10554,"journal":{"name":"Comprehensive psychiatry","volume":"143 ","pages":"Article 152639"},"PeriodicalIF":4.2,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145262340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Attention to Instagram features in female youth with anxiety symptoms 焦虑症状女性青年对Instagram特征的关注
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-10-06 DOI: 10.1016/j.comppsych.2025.152641
Youna McGowan , Bilikis Banire , Hailey Burns , Dawson Sutherland , Sherry H. Stewart , Raymond M. Klein , Sandra Meier
Social media's highly visual and interactive nature fosters social comparisons and can thereby exacerbate feelings of inadequacy, especially among youth with anxiety. Compared to their non-anxious peers, anxious youth are more likely to use social media and may be more susceptible to engaging in social comparison, as suggested by prior literature. Anxious youth are also more attentive to indicators of social status and threats. Thus, this study explored the attention bias mechanisms underlying anxiety in response to social media status cues (e.g., follower counts, likes). We predicted that with increasing anxiety symptoms, youth would avoid allocating their attention to these cues. We recruited 69 shy or anxious young females with anxiety symptoms to view Instagram profiles [Mage = 20.44 years, SDage = 1.84 years]. We recorded participants' eye movements with a high degree of spatial and temporal resolution while participants freely engaged with these profiles. Results showed that with increasing anxiety symptoms, youths' first fixation latency was significantly longer and their fixation duration shorter for social media status cues compared to the overall profile, representing an attentional avoidance pattern. This pattern was observed for both popular and less-popular profiles. These findings add to evidence that anxiety symptoms are linked to differences in visual attention to social media status cues. Further research is needed to examine these effects across genders, platforms, and in relation to other psychological constructs.
社交媒体的高度可视化和互动性助长了社会比较,从而加剧了不足感,尤其是在焦虑的年轻人中。与非焦虑的同龄人相比,焦虑的青少年更有可能使用社交媒体,并且可能更容易参与社会比较,正如先前的文献所表明的那样。焦虑的年轻人也更关注社会地位和威胁的指标。因此,本研究探讨了社交媒体状态线索(如关注者数量、点赞)下焦虑的注意偏差机制。我们预测,随着焦虑症状的增加,青少年会避免将注意力分配到这些线索上。我们招募了69名有焦虑症状的害羞或焦虑的年轻女性来查看Instagram个人资料[年龄= 20.44岁,年龄= 1.84岁]。我们以高度的空间和时间分辨率记录了参与者的眼球运动,同时参与者自由地参与这些轮廓。结果表明,随着焦虑症状的增加,青少年对社交媒体状态线索的第一次注视潜伏期显著延长,注视持续时间显著缩短,呈现注意回避模式。在流行和不太流行的概要文件中都观察到这种模式。这些发现进一步证明,焦虑症状与对社交媒体状态线索的视觉注意力差异有关。需要进一步的研究来检验这些影响在性别、平台以及与其他心理结构的关系。
{"title":"Attention to Instagram features in female youth with anxiety symptoms","authors":"Youna McGowan ,&nbsp;Bilikis Banire ,&nbsp;Hailey Burns ,&nbsp;Dawson Sutherland ,&nbsp;Sherry H. Stewart ,&nbsp;Raymond M. Klein ,&nbsp;Sandra Meier","doi":"10.1016/j.comppsych.2025.152641","DOIUrl":"10.1016/j.comppsych.2025.152641","url":null,"abstract":"<div><div>Social media's highly visual and interactive nature fosters social comparisons and can thereby exacerbate feelings of inadequacy, especially among youth with anxiety. Compared to their non-anxious peers, anxious youth are more likely to use social media and may be more susceptible to engaging in social comparison, as suggested by prior literature. Anxious youth are also more attentive to indicators of social status and threats. Thus, this study explored the attention bias mechanisms underlying anxiety in response to social media status cues (e.g., follower counts, likes). We predicted that with increasing anxiety symptoms, youth would avoid allocating their attention to these cues. We recruited 69 shy or anxious young females with anxiety symptoms to view Instagram profiles [<em>M</em><sub>age</sub> = 20.44 years, <em>SD</em><sub>age</sub> = 1.84 years]. We recorded participants' eye movements with a high degree of spatial and temporal resolution while participants freely engaged with these profiles. Results showed that with increasing anxiety symptoms, youths' first fixation latency was significantly longer and their fixation duration shorter for social media status cues compared to the overall profile, representing an attentional avoidance pattern. This pattern was observed for both popular and less-popular profiles. These findings add to evidence that anxiety symptoms are linked to differences in visual attention to social media status cues. Further research is needed to examine these effects across genders, platforms, and in relation to other psychological constructs.</div></div>","PeriodicalId":10554,"journal":{"name":"Comprehensive psychiatry","volume":"143 ","pages":"Article 152641"},"PeriodicalIF":4.2,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145262341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Comprehensive psychiatry
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