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Unraveling the neurophysiological underpinnings of social anxiety through body language: An ERP study 通过肢体语言揭示社交焦虑的神经生理基础:一项ERP研究
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-06-23 DOI: 10.1016/j.comppsych.2025.152617
Jiajia Jin , Xinyi Zhu , Wen Lian , Lu Fan

Objective

Body language plays a vital role in emotion perception, yet the involuntary neural mechanisms through which individuals with social anxiety process these signals remain unclear. This research investigates these mechanisms by analyzing visual components such as P3a, P1, and N190 within a three-stimulus oddball paradigm.

Method

Participants were classified into high social anxiety (HSA, n = 31) and low social anxiety (LSA, n = 26) groups using the Liebowitz Social Anxiety Scale (LSAS). The paradigm employed custom-designed distractors depicting positive, negative, and neutral body expressions to examine the involuntary processing of these stimuli.

Results

The findings indicate that individuals with high social anxiety (HSA) showed significantly higher P3a amplitudes than those with low social anxiety (LSA), especially for positive body expressions. In contrast, negative expressions elicited the weakest amplitudes. The N190 component responded most strongly to positive expressions and least to negative ones, while the P1 component showed uniform responses across all types.

Conclusions

HSA individuals process body expressions more intensely and are highly sensitive to them, regardless of valence. This insight can inform interventions targeting their cognitive and emotional biases.
肢体语言在情绪感知中起着至关重要的作用,但社交焦虑个体处理这些信号的非自愿神经机制尚不清楚。本研究通过在三刺激古怪范式中分析P3a、P1和N190等视觉成分来探讨这些机制。方法采用Liebowitz社交焦虑量表(LSAS)将被试分为高社交焦虑组(HSA, n = 31)和低社交焦虑组(LSA, n = 26)。该范式采用定制设计的描绘积极、消极和中性身体表情的干扰物来检查这些刺激的非自愿加工。结果高社交焦虑(HSA)个体的P3a波幅显著高于低社交焦虑(LSA)个体,尤其是对积极的身体表达。相反,消极表达引起的振幅最弱。N190组分对积极表达的响应最强烈,对消极表达的响应最小,而P1组分在所有类型中表现出一致的响应。结论shsa个体对身体表达的加工更强烈,且对其高度敏感,无论其价态如何。这种见解可以为针对他们的认知和情感偏见的干预提供信息。
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引用次数: 0
Pilot implementation of an online program for family and friends supporting the mental health of paramedics in Australia: Lessons learned. 支持澳大利亚护理人员心理健康的家庭和朋友在线方案的试点实施:经验教训。
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-06-15 DOI: 10.1016/j.comppsych.2025.152614
Philippa Ditton-Phare , Tina Fox , Kristen Vallender , Jose Cuenca , Sally Fitzpatrick

Introduction

Paramedics experience disproportionately high rates of mental health concerns, often relying on informal support from family and friends. While this support is vital, it can impose significant strain on family and friends, who frequently lack the necessary resources and skills for their role. To address this, a novel online program, Minds Together, was developed specifically for family and friends to enhance their ability to support the mental health of paramedics while prioritizing their own mental health and wellbeing.

Methods

The feasibility and acceptability of the program was evaluated through a pilot study involving 53 participants randomized to either program or waitlist groups. Data collection included pre- and post-intervention surveys, program usage metrics, post-project surveys, and feedback from user testing. The Global Impact Analytics Framework (GIAF) guided analysis of planning, pre-engagement, pre-readiness, usability, dissemination, adoption, and contextual factors.

Results

Participants valued the program for its lived-experience content and self-paced format. Broad dissemination reached over one million individuals, and usability and relevance were rated highly. However, low engagement and completion rates reflected challenges common to online interventions. Barriers included limited access duration, participants' time constraints, and difficulties in reaching the target audience. Suggestions included flexible access, advanced content options, and targeted outreach strategies.

Conclusion

Minds Together shows promise as a scalable intervention for family and friends of paramedics. Future research will address barriers, explore long-term outcomes, and refine the program to better meet family and friends' diverse needs, improving mental health support for paramedics and their support network.
护理人员经历不成比例的高比率的心理健康问题,往往依赖于家庭和朋友的非正式支持。虽然这种支持是至关重要的,但它会给家人和朋友带来巨大的压力,因为他们往往缺乏必要的资源和技能来发挥自己的作用。为了解决这个问题,专门为家人和朋友开发了一个新颖的在线项目,名为“同心协力”,以提高他们支持护理人员心理健康的能力,同时优先考虑他们自己的心理健康和福祉。方法通过一项涉及53名参与者的试点研究来评估该计划的可行性和可接受性,该研究随机分为计划组和候补组。数据收集包括干预前和干预后调查、程序使用度量、项目后调查以及来自用户测试的反馈。全球影响分析框架(GIAF)指导了对规划、预参与、预准备、可用性、传播、采用和背景因素的分析。结果参与者对该项目的现场体验内容和自定节奏的形式非常重视。广泛传播达到100多万人,可用性和相关性评价很高。然而,较低的参与率和完成率反映了在线干预面临的共同挑战。障碍包括访问时间有限、参与者的时间限制以及难以接触目标受众。建议包括灵活的访问、先进的内容选择和有针对性的推广策略。结论minds Together有望成为护理人员家属和朋友可扩展的干预措施。未来的研究将解决障碍,探索长期结果,并完善该计划,以更好地满足家人和朋友的不同需求,改善对护理人员及其支持网络的心理健康支持。
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引用次数: 0
Shifting organizational sentiment: Qualitative insights from a mental ill-health prevention program for New Zealand firefighters 转变组织情绪:定性的见解从精神疾病预防计划为新西兰消防员
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-06-13 DOI: 10.1016/j.comppsych.2025.152615
Jessica L. Campbell , Josh Darby , Paul Oswald , Lisa Mackay , Grant Schofield

Background

Firefighters are regularly exposed to potentially psychologically traumatic events (PPTEs), significantly increasing their risk of mental ill-health. Organizational factors such as leadership, support, and workload also influence these outcomes.

Purpose

This study evaluates the Whanaungatanga Program, a participatory initiative designed to address organizational factors affecting firefighter well-being, focusing on early changes in sentiment.

Methods

We conducted a qualitative analysis of open-text responses from two surveys (embedded within broader mental health questionnaires) with firefighters and commanders, and semi-structured interviews with commanders. Thematic and sentiment analyses explored perceptions of organizational interventions and the emotional tone in responses across two time points.

Main Findings

In the pilot region receiving interventions, organizational sentiment shifted substantially: positive sentiment increased from 13 % to 48 %, negative sentiment decreased over 20 % (from 66 % to 40 %), and themes such as improved leadership visibility emerged, reflecting rapid cultural progress.

Conclusions

The results highlight the effectiveness of targeted, participatory interventions in fostering positive organizational change. Marked improvements in sentiment indicate that even in high-stress environments, well-designed interventions can lead to substantial benefits in employee sentiment and organizational culture.
消防员经常暴露在潜在心理创伤事件(ppte)中,这大大增加了他们患精神疾病的风险。组织因素,如领导力、支持和工作量也会影响这些结果。本研究评估了Whanaungatanga项目,这是一项参与性倡议,旨在解决影响消防员幸福感的组织因素,重点关注情绪的早期变化。方法:我们对消防员和指挥官的两项开放式文本调查(嵌入在更广泛的心理健康问卷中)以及对指挥官的半结构化访谈进行了定性分析。主题和情绪分析探讨了组织干预的感知和两个时间点的反应中的情绪基调。在接受干预的试点地区,组织情绪发生了重大变化:积极情绪从13%上升到48%,消极情绪下降了20%以上(从66%降至40%),并且出现了诸如提高领导力可见度等主题,反映了文化的快速进步。结论:研究结果强调了有针对性的参与性干预在促进积极的组织变革方面的有效性。情绪的显著改善表明,即使在高压力环境中,精心设计的干预措施也能给员工情绪和组织文化带来实质性的好处。
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引用次数: 0
Pathways to suicidal ideation for young people engaged in mental health care 从事精神卫生保健的年轻人产生自杀意念的途径
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-06-13 DOI: 10.1016/j.comppsych.2025.152611
Mathew Varidel , Ian B. Hickie , Victor An , Sally Cripps , Roman Marchant , Jo Robinson , Louise La Sala , William Capon , Ashlee Turner , Alexander Tashevski , Elizabeth Scott , Frank Iorfino

Background

Suicidal thoughts and behaviours (STBs) have a profound impact on individuals, communities, and healthcare systems. A wide range of factors have been shown to be associated with STBs. Within prior research it is also common to distinguish between proximal and distal factors, usually by distinction of short compared to long-term prediction.

Objective

We aimed to learn the proximal and distal factors of suicidal ideation for young people engaged in mental health care using the inferred structure of probabilistic graphical models (PGMs).

Methods and materials

We used cross-sectional data from a sample of 1020 help-seeking individuals aged 12–25 years from Australia that while engaged in mental health care, contributed data to a digital platform. The posterior distribution of the dependency structure assuming both undirected PGMs and Bayesian networks (BNs) was inferred. Causal effects were then estimated using a counterfactual query of the Bayesian networks.

Results

Depressed mood, functional impairment, poor social connection, and psychosis-like experiences were proximal factors. Whereas experiencing a traumatic event, anxiety, insomnia, and unrefreshed sleep were distal factors. Proximal factors had the greatest effect on suicidal ideation, while anxiety symptoms and experiencing a traumatic event were the most influential distal factors.

Conclusions

These relative timings of events and their effects on suicidal ideation could be used to understand the future likelihood of suicidal ideation, and aid planning of targeted interventions.
自杀念头和行为(STBs)对个人、社区和医疗保健系统产生深远影响。与性传播疾病有关的因素有很多。在先前的研究中,区分近端和远端因素也很常见,通常是通过区分短期与长期预测。目的应用概率图模型(PGMs)的推断结构,了解从事精神卫生保健的青少年自杀意念的近端和远端因素。方法和材料我们使用了来自澳大利亚的1020名年龄在12-25岁之间寻求帮助的个人样本的横截面数据,这些人在从事精神卫生保健的同时,向数字平台提供了数据。推导了无向pgm和贝叶斯网络的依赖结构后验分布。然后使用贝叶斯网络的反事实查询来估计因果效应。结果情绪抑郁、功能障碍、社会联系不良和精神病样经历是近端因素。而经历创伤性事件、焦虑、失眠和睡眠不足是远端因素。近端因素对自杀意念的影响最大,而焦虑症状和经历创伤事件是影响最大的远端因素。结论这些事件的相对时间及其对自杀意念的影响可以用来了解未来自杀意念的可能性,帮助制定有针对性的干预措施。
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引用次数: 0
The role of attachment anxiety and intolerance of uncertainty in gaming during adolescence: A two-wave longitudinal study 依恋焦虑和对不确定性的不容忍在青少年游戏中的作用:一项两波纵向研究
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-06-07 DOI: 10.1016/j.comppsych.2025.152613
Camilla Gregorini , Claudia Marino , Alessandro Giardina , Joël Billieux , Gioia Bottesi , Chiara Sacchi , Erika Pivetta , Alessio Vieno , Natale Canale
Adolescents with attachment anxiety can compensate via gaming for their unmet needs of closeness, reassurance, and emotion regulation. However, individual factors linking attachment anxiety to compensation via gaming are still unclear. In this two-wave longitudinal study (Wave 1, W1 = baseline; Wave 2, W2 = 6 months later), we aimed to determine whether intolerance of uncertainty (IU) mediates the link between attachment anxiety and gaming behaviours (gaming compensation, gaming frequency, and problematic gaming). Online questionnaires were administered to Italian adolescent gamers (N = 570; Mage = 15.60; SDage = 1.56; 68.8 % males). First, via path analyses, we tested whether attachment anxiety towards mother and father (W1) and IU (W1) would predict gaming behaviours (W2). Second, we tested whether IU would mediate the link between attachment anxiety and gaming compensation specifically. Multigroup analysis was used to explore gender differences. We found that attachment anxiety towards the mother and father was positively associated with IU, whereas attachment anxiety towards only the mother predicted gaming compensation at W2 both directly and via IU. Moreover, IU positively predicted gaming compensation and problematic gaming at W2. Multigroup analysis further revealed that for females, attachment anxiety towards the mother positively predicted gaming compensation at W2. Findings revealed small/modest effect sizes. Overall, attachment anxiety and IU may boost individuals to compensate via gaming, increasing the risk of problematic gaming. These results hold implications for future prevention interventions, emphasizing the quality of the parent-child relationship and IU as potential targets to foster adaptive coping strategies in adolescence.
患有依恋焦虑的青少年可以通过游戏来弥补他们对亲密、安慰和情绪调节的未满足需求。然而,将依恋焦虑与游戏补偿联系起来的个体因素仍不清楚。在这项两波纵向研究中(波1,W1 =基线;第二阶段(W2 = 6个月后),我们旨在确定不确定性不耐受(IU)是否介导了依恋焦虑和游戏行为(游戏补偿、游戏频率和问题游戏)之间的联系。对意大利青少年游戏玩家进行在线问卷调查(N = 570;法师= 15.60;SDage = 1.56;68.8%男性)。首先,通过路径分析,我们测试了对父母(W1)和IU (W1)的依恋焦虑是否会预测游戏行为(W2)。其次,我们测试了IU是否会调解依恋焦虑和游戏补偿之间的联系。采用多组分析探讨性别差异。我们发现,对母亲和父亲的依恋焦虑与IU呈正相关,而对母亲的依恋焦虑直接或通过IU预测W2的游戏补偿。此外,IU积极预测W2的游戏补偿和问题游戏。多组分析进一步显示,对母亲的依恋焦虑对W2的游戏补偿有正向预测作用。研究结果显示了小/中等的效应大小。总体而言,依恋焦虑和IU可能会促使个体通过游戏进行补偿,从而增加问题游戏的风险。这些结果对未来的预防干预具有启示意义,强调亲子关系的质量和IU是培养青少年适应性应对策略的潜在目标。
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引用次数: 0
Characteristics of adolescents hospitalised in adult psychiatric units. Retrospective study in the largest psychiatric hospital in France 成人精神科住院青少年的特征。在法国最大的精神病院进行回顾性研究
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-06-06 DOI: 10.1016/j.comppsych.2025.152612
Alexandra Pham-Scottez , Isabelle Sabbah-Lim , Jean Chambry , Valérie Dao , Raphael Gourevitch , David Barruel Ing , Valérie Dauriac-Le Masson
Although psychiatrists working with adolescents know that sometimes they need to be hospitalised in emergency, few studies have described the hospitalisation of adolescents in adult psychiatric wards. We aimed to estimate the prevalence of adolescents hospitalised in adult psychiatric wards (characteristics, gender comparison, subtypes).
We conducted a monocentric retrospective study in the largest psychiatric hospital in France. All patients aged 15 to <18 years hospitalised in adult psychiatric wards were included, with different variables: socio-demographic and family information, history of inpatient / outpatient treatment, clinical data (like ICD-10 diagnoses, care pathway before / after hospitalisation…).
We included 332 hospitalisations (70 % girls), representing 2.8 % of all psychiatric hospitalisations. For 37 hospitalisations (11.1 %), this was the first psychiatric contact; for 54.2 %, patients had no previous psychiatric hospitalisation, for 87.3 %, patients had previous outpatient treatment. Mood disorders was the diagnosis for 47 % of the admissions, suicide attempts and suicidal ideation accounted for 69 % of the clinical situations leading to hospitalisation. Boys and girls differed significantly on many variables. Cluster analyses revealed two subgroups: cluster 1 patients (62 %) more frequently were girls, had previous hospitalisations in child psychiatry, came from home, had suicide attempts / suicidal ideation, had personality disorders, whereas cluster 2 patients (38 %) more frequently had substance use disorders, psychotic episodes, clastic crisis / hetero-aggression, longer hospital stays. Emergency admission of an adolescent with psychiatric issues to an adult psychiatric ward is not uncommon, especially in the context of a suicidal crisis or psychotic episode. Our results suggest the need for establishing unscheduled hospital beds for such adolescents.
虽然与青少年一起工作的精神科医生知道,有时他们需要在紧急情况下住院,但很少有研究描述青少年在成人精神病病房的住院情况。我们的目的是估计在成人精神病病房住院的青少年的患病率(特征、性别比较、亚型)。我们在法国最大的精神病院进行了一项单中心回顾性研究。所有在成人精神科病房住院的15至18岁的患者被纳入研究,包括不同的变量:社会人口统计学和家庭信息、住院/门诊治疗史、临床数据(如ICD-10诊断、住院前后的护理途径……)。我们纳入了332例住院病例(70%为女孩),占所有精神病住院病例的2.8%。在37例住院(11.1%)中,这是第一次精神病接触;54.2%的患者以前没有精神科住院治疗,87.3%的患者以前有门诊治疗。47%的入院患者被诊断为情绪障碍,69%的临床病例被诊断为自杀企图和自杀意念。男孩和女孩在许多变量上存在显著差异。聚类分析揭示了两个亚组:第一类患者(62%)更多的是女孩,以前曾在儿童精神病院住院,来自家庭,有自杀企图/自杀意念,有人格障碍,而第二类患者(38%)更多的是物质使用障碍,精神病发作,破裂危机/异性恋攻击,住院时间较长。有精神问题的青少年被紧急送入成人精神病房并不罕见,尤其是在自杀危机或精神病发作的情况下。我们的研究结果表明,有必要为这些青少年建立不定期的医院床位。
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引用次数: 0
The double-edged sword of distress tolerance: Exploring the role of distress overtolerance in nonsuicidal self-injury 痛苦容忍的双刃剑:探讨痛苦过度容忍在非自杀性自伤中的作用
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-06-06 DOI: 10.1016/j.comppsych.2025.152610
Harin Chung, Gyumyoung Kim, Da-In Kim, Ji-Won Hur

Background

While low distress tolerance has been widely studied as a risk factor for nonsuicidal self-injury (NSSI), recent attention has shifted toward distress overtolerance—an individual's excessive endurance to distress despite severe adverse effects. Understanding this double-edged nature of distress tolerance is critical for developing effective intervention strategies to address the growing burden of NSSI. This study investigated the role of distress overtolerance in NSSI pathology.

Methods

The study comprised 1818 female participants, including 918 and 900 participants with and without a history of NSSI, respectively. Binary logistic regression models were utilized to analyze distress overtolerance as a predictor of NSSI engagement, versatility, and frequency while controlling for demographic variables, depression, anxiety, and emotion dysregulation. Among the participants with a history of NSSI, Pearson's correlation analyses were conducted to identify the functions of NSSI that were the most associated with distress overtolerance.

Results

Distress overtolerance was identified as a significant predictor of NSSI engagement, versatility, and frequency even after controlling for other risk factors. Distress overtolerance was most strongly linked to self-punishment function in individuals with a history of NSSI.

Conclusions

Distress overtolerance is a distinct and significant risk factor for NSSI, highlighting the need for its inclusion in mechanisms and intervention models for NSSI. Addressing distress overtolerance in therapeutic settings to achieve an optimal balance in distress regulation could provide innovative and more effective strategies for the treatment of NSSI.
背景:低痛苦承受能力作为非自杀性自伤(NSSI)的一个危险因素被广泛研究,最近的注意力转向了痛苦过度承受——个体对痛苦的过度承受,尽管有严重的不良影响。理解这种痛苦容忍的双刃剑性质对于制定有效的干预策略来解决自伤日益增加的负担至关重要。本研究探讨了应激过度耐受在自伤病理中的作用。方法本研究纳入1818名女性受试者,其中有自伤史的918名,无自伤史的900名。在控制人口统计变量、抑郁、焦虑和情绪失调的情况下,利用二元逻辑回归模型分析作为自伤参与、多功能性和频率预测因子的痛苦过度耐受。在有自伤史的参与者中,进行Pearson相关分析,以确定与痛苦过度耐受最相关的自伤功能。结果即使在控制了其他风险因素后,痛苦过度耐受也被确定为自伤参与、多功能性和频率的重要预测因子。在有自伤史的个体中,痛苦过度耐受与自我惩罚功能的关系最为密切。结论痛苦过度耐受是自伤的一个明显且重要的危险因素,需要将其纳入自伤机制和干预模式。在治疗环境中解决痛苦过度耐受,以实现痛苦调节的最佳平衡,可以为治疗自伤提供创新和更有效的策略。
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引用次数: 0
Inpatient vs outpatient cognitive behavioral therapy for insomnia: A two-arm parallel randomized controlled trial 失眠症的住院与门诊认知行为疗法:一项平行随机对照试验
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-23 DOI: 10.1016/j.comppsych.2025.152609
Guifeng Li , Mengya Li , Xin Xu , Junhong Zhang , Qifang Li , Qing Cai

Objective

While outpatient cognitive behavioral therapy for insomnia (CBT-I) represents the most efficacious delivery method, approximately 50 % of patients are unable to achieve clinical remission. There is a pressing need to develop more effective approaches to CBT-I delivery. This study assessed the comparative efficacy of one-week inpatient CBT-I and eight-week standard outpatient CBT-I.

Methods

A randomized controlled trial was conducted with 200 adults with chronic insomnia disorder. These participants were randomly allocated to either the inpatient group (n = 100) or the outpatient group (n = 100). The inpatient group underwent a one-week intensive inpatient CBT-I followed by weekly follow-ups program. The outpatient group participated in a standard outpatient CBT-I program conducted on an individual basis over an eight-week period. The primary outcome was the insomnia severity index score at 9 weeks after the start of intervention. Linear mixed effects model was employed for the intention-to-treat analysis.

Results

At the 9-week assessment, the inpatient CBT-I group demonstrated a mean change in insomnia severity index score of −13.31 (95 % confidence interval [CI], −14.47 to −12.16; Cohen's d = −3.18; P < .001). The outpatient group showed a mean change of −11.14 (95 % CI, −12.30 to −9.98; Cohen's d = −2.66; P < .001). The mean difference between groups was −2.03 (95 % CI, −3.21 to −0.85; Cohen's d = −0.48; P < .001), indicating a statistically significant improvement in the inpatient group compared to the outpatient group.

Conclusions

This study demonstrated that inpatient CBT-I exhibited superior efficacy compared to outpatient CBT-I in alleviating insomnia severity.
目的:虽然门诊认知行为治疗失眠(CBT-I)是最有效的治疗方法,但约50%的患者无法达到临床缓解。迫切需要制定更有效的CBT-I交付方法。本研究评估了住院1周的CBT-I和标准门诊8周的CBT-I的比较疗效。方法对200例成人慢性失眠症患者进行随机对照试验。这些参与者被随机分配到住院组(n = 100)或门诊组(n = 100)。住院组接受了为期一周的强化住院CBT-I,随后是每周的随访计划。门诊组参加了一个标准的门诊CBT-I项目,以个人为基础,为期八周。主要结果是干预开始后9周的失眠严重程度指数评分。意向-治疗分析采用线性混合效应模型。结果在9周的评估中,住院患者CBT-I组失眠严重程度指数得分的平均变化为- 13.31(95%置信区间[CI], - 14.47至- 12.16;Cohen’s d =−3.18;P & lt;措施)。门诊组平均变化为- 11.14 (95% CI, - 12.30 ~ - 9.98;Cohen’s d =−2.66;P & lt;措施)。组间平均差异为- 2.03 (95% CI, - 3.21 ~ - 0.85;Cohen’s d = - 0.48;P & lt;.001),表明住院组与门诊组相比有统计学上的显著改善。结论与门诊患者相比,住院患者CBT-I在减轻失眠严重程度方面表现出更强的疗效。
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引用次数: 0
Mapping psychiatric comorbidity network: A pilot multi-method weighted network analysis with a focus on key disorders 映射精神共病网络:一个试点多方法加权网络分析与重点疾病
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-23 DOI: 10.1016/j.comppsych.2025.152608
Yu Chang , Si-Sheng Huang , Wen-Yu Hsu , Yi-Chun Liu

Background

Psychiatric comorbidity is a prevalent phenomenon that imposes a significant burden on patients, healthcare systems, and society. However, current research on psychiatric comorbidity is often limited to single disorders or partial associations. This study aims to utilize network analysis methods to construct a psychiatric comorbidity network and explore the network structural characteristics under different network weight definitions.

Method

Based on the psychiatric outpatient data from Changhua Christian Hospital in Taiwan from January 1, 2016, to June 30, 2024, the ICD-10 diagnostic codes (F00-F99) of all patients that appeared at least three times were extracted. Three different comorbidity networks were constructed using co-occurrence counts, Jaccard index, and partial correlation coefficient estimated by the mixed graphical model (MGM) as the weights of the network edges. Network structure was analyzed using indicators such as degree centrality, modularity, and community detection.

Results

The dataset included 16,954 patients. The comorbidity frequency network showed that mood disorders (F34) and anxiety disorders (F41) had the highest weighted degree centrality. In the Jaccard coefficient network, the weighted degree centrality of developmental disorders (F8x) increased. The MGM network highlighted the central role of substance use disorders (F1x).

Conclusion

Our findings suggested the roles and interrelationships of different disease categories in the comorbidity network. The results provide new perspectives and data support for clinical practice and future research.
精神疾病共病是一种普遍现象,给患者、卫生保健系统和社会带来了沉重的负担。然而,目前对精神疾病共病的研究往往局限于单一疾病或部分关联。本研究旨在运用网络分析方法构建精神共病网络,探讨不同网络权重定义下的网络结构特征。方法根据台湾彰化基督教医院2016年1月1日至2024年6月30日的精神科门诊资料,提取出现至少3次的所有患者的ICD-10诊断码(F00-F99)。利用共现数、Jaccard指数和由混合图形模型(MGM)估计的偏相关系数作为网络边的权值,构建了三种不同的共病网络。使用度中心性、模块化和社区检测等指标分析网络结构。结果数据集包括16,954例患者。共病频率网络显示,情绪障碍(F34)和焦虑障碍(F41)的加权度中心性最高。在Jaccard系数网络中,发育障碍的加权度中心性(F8x)增加。米高梅网络强调了物质使用障碍的核心作用(F1x)。结论不同疾病类型在合并症网络中的作用和相互关系。研究结果为临床实践和今后的研究提供了新的视角和数据支持。
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引用次数: 0
Screening accuracy of the German version of the benzodiazepine self-report questionnaire 德文版苯二氮卓类自我报告问卷的筛选准确性
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-18 DOI: 10.1016/j.comppsych.2025.152607
M.W. Stratmann , J. Heeg , M. Härter , L. Kriston , U. Verthein , C. Lindemann

Background and aims

We aimed to assess the accuracy for the German version of the Benzodiazepine Dependence Self-Report Questionnaire (Bendep-SRQ-GV) as a possible screening instrument for benzodiazepine or Z-drug substance use disorder.

Method

This study includes a convenience sample of adults who had used benzodiazepines or Z-drugs at least once in the last year. Participants were recruited through notice boards, social media, newspaper, and a digital health information platform. All participants answered the Bendep-SRQ-GV and were assessed for benzodiazepine or Z-drug substance use disorder using the Structured Clinical Interview for DSM-5 Disorders – Clinical Version. We performed receiver operating characteristics curve analyses and calculated the area under the curve (AUC).

Results

42 out of 60 participants fulfilled the criteria for benzodiazepine or Z-drug substance use disorder according to Structured Clinical Interview. AUCs varied among the 4 subscales of the Bendep-SRQ-GV: Problematic Use (0.893 [0.819–0.975]), Preoccupation (0.751 [0.609–0.892]), Lack of Compliance (0.804 [0.699–0.919]), Withdrawal (0.743 [0.622–0.864]) and Total Score (0.860 [0.762–0.963]). For Problematic Use and Total Score selected cut-offs (5.5 and 16.5) showed best results: sensitivity (83 % [71–93 %] and 79 % [67–90 %]), high specificity (83 % [61–100 %] and 83 % [67–100 %], positive predictive value (92 % [84–100 %] and 92 % [83–100 %]), and negative predictive value (68 % [54–85 %] and 63 % [50–77 %]).

Discussion

The subscale Problematic Use and the Total Score seem promising for detecting benzodiazepine or Z-drug substance use disorder in adults. Precise cut-offs should be determined with a larger sample. The Bendep-SRQ-GV could be of great value as a screening questionnaire in clinical settings, counselling sites, and for scientific purposes.
背景与目的本研究旨在评估德文版苯二氮卓类药物依赖自我报告问卷(bendeep - srq - gv)作为苯二氮卓类药物或z类药物使用障碍筛查工具的准确性。方法本研究选取在过去一年中至少使用过一次苯二氮卓类药物或z类药物的成年人作为方便样本。参与者是通过布告栏、社交媒体、报纸和数字健康信息平台招募的。所有参与者都回答了bendeep - srq - gv,并使用DSM-5障碍-临床版结构化临床访谈评估苯二氮卓类或z -药物物质使用障碍。进行受试者工作特征曲线分析,计算曲线下面积(AUC)。结果根据结构化临床访谈,60名参与者中有42人符合苯二氮卓类药物或z类药物使用障碍标准。bendeep - srq - gv量表的auc分别为:问题使用(0.893[0.819-0.975])、关注(0.751[0.609-0.892])、缺乏依从性(0.804[0.699-0.919])、戒断(0.743[0.622-0.864])和总分(0.860[0.762-0.963])。对于有问题的使用和总分选择的截断值(5.5和16.5)显示出最佳结果:敏感性(83%[71 - 93%]和79%[67 - 90%]),高特异性(83%[61 - 100%]和83%[67 - 100%],阳性预测值(92%[84 - 100%]和92%[83 - 100%]),阴性预测值(68%[54 - 85%]和63%[50 - 77%])。问题使用量表和总分似乎有希望检测成人苯二氮卓类药物或z类药物使用障碍。精确的截止值应该用更大的样本来确定。bendeep - srq - gv可以作为临床环境、咨询场所和科学目的的筛查问卷,具有很大的价值。
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引用次数: 0
期刊
Comprehensive psychiatry
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