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Mapping the pathway to anabolic-androgenic steroids (AAS) use 绘制合成代谢雄激素类固醇(AAS)使用途径
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-15 DOI: 10.1016/j.comppsych.2025.152602
Nora M. Laskowski , Christopher Zaiser , Roland Müller , Gerrit Brandt , Georgios Paslakis
This short communication introduces a model for the use of anabolic-androgenic steroids (AAS), with body dissatisfaction as the central factor, shaped by sociocultural, psychological, and behavioral influences. Media-driven body ideals, gender, and sexual orientation may significantly influence body image, while low self-esteem and certain personality traits also contribute to dissatisfaction. Disordered eating behaviors (DEB) and intense physical exercise act as indirect contributors, particularly in fitness communities, where “conventional” body modification methods (i.e., exercise and diet) may fail to meet internalized ideals.
The model highlights a vicious cycle: body dissatisfaction drives AAS use, which, in turn, worsens dissatisfaction. Social media amplify this cycle by promoting unrealistic standards, while marginalized groups, including LGBTQI+ populations, face additional pressures to conform to heteronormative beauty norms. The overlap between body dissatisfaction, DEB, and intense physical exercise underscores the need for nuanced research to disentangle these inferences.
The model predominantly reflects Western body ideals, limiting its applicability across cultures. Addressing body dissatisfaction through early interventions targeting both societal standards and individual vulnerabilities is critical. Also, approaches accounting for aspects of sex and gender diversity are essential to promote body acceptance and reduce the risk of AAS use and DEB.
这篇简短的交流介绍了一个使用合成代谢雄激素类固醇(AAS)的模型,以身体不满意为中心因素,受社会文化、心理和行为影响。媒体驱动的身体理想、性别和性取向可能会显著影响身体形象,而低自尊和某些人格特质也会导致不满意。饮食失调行为(DEB)和剧烈的体育锻炼是间接因素,特别是在健身社区,“传统”的身体改造方法(即运动和饮食)可能无法满足内在理想。该模型强调了一个恶性循环:对身体的不满推动了AAS的使用,而AAS的使用又加剧了对身体的不满。社交媒体通过推广不切实际的标准放大了这个循环,而包括LGBTQI+人群在内的边缘群体则面临着遵守异性恋标准的额外压力。身体不满意、DEB和高强度体育锻炼之间的重叠强调了细致的研究来解开这些推论的必要性。该模型主要反映了西方的身体理想,限制了它在不同文化中的适用性。通过针对社会标准和个人脆弱性的早期干预来解决身体不满是至关重要的。此外,考虑性别和性别多样性方面的方法对于促进身体接受和降低AAS使用和DEB的风险至关重要。
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引用次数: 0
Corrigendum to “Neural mechanism of non-adaptive cognitive emotion regulation in patients with non-suicidal self-injury” [Comprehensive Psychiatry Volume 133 (2024) 152487] 对“非自杀性自伤患者的非适应性认知情绪调节的神经机制”的更正[综合精神病学卷133(2024)152487]。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-13 DOI: 10.1016/j.comppsych.2025.152601
Nan Lang , Sichu Wu , Yuan Zhong , Wenkun Lei , Yiwen Xiao , Yaming Hang , Ya Xie , Zhangwei Lv , Yumin Zhang , Xinyao Liu , Minlu Liang , Congjie Zhang , Pei Zhang , Hua Yang , Yun Wu , Qiuyu Wang , Kun Yang , Jing Long , Yuan Liu , Suhong Wang , Chun Wang
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引用次数: 0
The LEADING guideline: Reporting standards for expert panel, best-estimate diagnosis, and longitudinal expert all data (LEAD) methods 主要指南:专家小组报告标准,最佳估计诊断和纵向专家所有数据(LEAD)方法
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-13 DOI: 10.1016/j.comppsych.2025.152603
Veerle C. Eijsbroek , Katarina Kjell , H. Andrew Schwartz , Jan R. Boehnke , Eiko I. Fried , Daniel N. Klein , Peik Gustafsson , Isabelle Augenstein , Patrick M.M. Bossuyt , Oscar N.E. Kjell
Accurate assessments of symptoms and illnesses are essential for health research and clinical practice but face many challenges. The absence of a single error-free measure is currently addressed by assessment methods involving experts reviewing several sources of information to achieve a best-estimate assessment. This assessment method is called the Expert Panel method in medicine, and the Best-Estimate Diagnosis or Longitudinal Expert All Data (LEAD) method in psychiatry and psychology. However, due to poor reporting of the assessment methods, the quality of pro-claimed best-estimate assessments is typically difficult to evaluate, and when the method is reported, the reporting quality varies substantially. To tackle this gap, we have developed a reporting guideline following a four-stage approach: 1) drafting reporting standards accompanied by empirical evidence, which were further developed with a patient organization for depression, 2) incorporating expert feedback through a two-round Delphi procedure, 3) refining the guideline based on an expert consensus meeting, and 4) testing the guideline by i) having researchers test it and ii) applying it to previously published studies. The last step also provides evidence for the need for the guideline: 10–63 % (Mean 33 %) of the standards were not reported across thirty randomly selected published studies. The result is the LEADING guideline comprising 20 reporting standards in four groups: the Longitudinal design, the Appropriate data, the Evaluation – experts, materials and procedures, and the Validity group. We hope that the LEADING guideline will assist researchers in planning, conducting, reporting, and evaluating research aiming to achieve best-estimate assessments.
对症状和疾病的准确评估对健康研究和临床实践至关重要,但面临许多挑战。目前的评估方法是由专家审查几个信息来源,以实现最佳估计评估,以解决缺乏单一的无差错措施的问题。这种评估方法在医学上被称为专家小组方法,在精神病学和心理学上被称为最佳估计诊断或纵向专家所有数据(LEAD)方法。然而,由于对评估方法的不良报告,主张的最佳估计评估的质量通常难以评估,并且当报告方法时,报告质量会发生很大变化。为了解决这一差距,我们制定了一个报告指南,遵循四个阶段的方法:1)起草报告标准,并伴有经验证据,与抑郁症患者组织一起进一步发展,2)通过两轮德尔菲程序纳入专家反馈,3)根据专家共识会议完善指南,4)通过i)让研究人员测试它,ii)将其应用于先前发表的研究来测试指南。最后一步也为指南的必要性提供了证据:在随机选择的30项已发表的研究中,10 - 63%(平均33%)的标准没有报告。结果是LEADING指南,包括四组20个报告标准:纵向设计,适当的数据,评估专家,材料和程序,以及有效性组。我们希望LEADING指南将帮助研究人员计划、实施、报告和评估旨在实现最佳估计评估的研究。
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引用次数: 0
A comparative evaluation of 23 projects on mental health and wellbeing for veterans and first responders 对23个退伍军人和急救人员心理健康和福利项目进行比较评价
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-03 DOI: 10.1016/j.comppsych.2025.152599
S. Lukersmith , C. Woods , L. Salvador-Carulla , T. Niyonsenga , I. Mohanty , M.R. Gutierrez-Colosia , D. Diaz-Milanes , C.R. Garcia-Alonso , C.J. Büsst

Background

Veterans and First Responders (VFR) are at risk of developing a range of mental health disorders because of cumulative exposure to critical incidents at work. Two Philanthropic organisations funded 15 organisations, which collectively implemented 23 highly heterogeneous and international early intervention mental ill-health and suicide prevention Projects. The aim was identify and collaborate with Projects with a multi-project evaluation. The evaluation examined multiple domains including intervention effectiveness but critically the implementation processes impacts for potential replication or scale up. This paper reports on the methods and evaluation results of implementation processes, impact analysis and sustainability.

Method

The evaluation involved ecosystems and complex systems approaches using novel methods and tools. There was multiple preparatory evaluation steps including developing indices for complexity and context. The Global Impact Analytics Framework (GIAF) toolkit was used to evaluate the implementation processes. Methodological tools included qualitative analysis, descriptive statistics, GIAF ladders/scales and checklists (qualitative and quantitative data).

Results

We provide the results on characteristics (organisational, Project and participants), GIAF process components (planning, pre-engagement, pre-readiness/readiness, dissemination/diffusion, usability/sustainability, adoption and uptake). All Project interventions were assessed as usable, adoptable and have capacity to be sustained, with financial resources. Uptake of the intervention was mostly high.

Conclusion

Complex multi-project evaluation of highly heterogenous Projects implemented in the real world across different countries is possible and provides valuable information and learnings. The evaluation results establish benchmarks including Project pre-engagement with potential end-users, continuous, frequent collaboration between Project and evaluation teams, adequate contract duration for sufficient recruitment and intervention.
退伍军人和急救人员(VFR)由于长期暴露于工作中的重大事件,有患一系列精神健康障碍的风险。两个慈善组织资助了15个组织,这些组织共同实施了23个高度多样化的国际早期干预精神疾病和自杀预防项目。其目的是通过多项目评估确定项目并与项目合作。评估审查了多个领域,包括干预有效性,但关键是实施过程对潜在复制或扩大规模的影响。本文报告了实施过程、影响分析和可持续性的方法和评价结果。方法采用新颖的方法和工具,对生态系统和复杂系统进行评价。有多个预备评价步骤,包括制定复杂性和背景指标。全球影响分析框架(GIAF)工具包用于评估实施过程。方法工具包括定性分析、描述性统计、GIAF阶梯/量表和核对表(定性和定量数据)。我们提供了关于特征(组织、项目和参与者)、GIAF过程组件(计划、预参与、预准备/准备、传播/扩散、可用性/可持续性、采用和吸收)的结果。所有项目干预措施都被评估为可用、可采用和有能力在财政资源的情况下持续下去。大多数人对干预措施的接受程度很高。结论对现实世界中不同国家实施的高度异质项目进行复杂的多项目评估是可能的,并提供了有价值的信息和学习。评估结果建立了基准,包括项目与潜在最终用户的预先接触,项目和评估团队之间持续、频繁的合作,为充分的招聘和干预提供足够的合同期限。
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引用次数: 0
Obsessive-compulsive spectrum disorders and the menstrual cycle: A scoping review 强迫性谱系障碍和月经周期:范围综述
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-01 DOI: 10.1016/j.comppsych.2024.152554
Juliette S. Mojgani , Anna M. Rzepka , Yejin Kang , Hashim Al-Bya , Beth Patterson , Michael Van Ameringen
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引用次数: 0
Immuno-moodulin (Imood) and its potential role in OCD 免疫调节素(Imood)及其在强迫症中的潜在作用
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-01 DOI: 10.1016/j.comppsych.2024.152550
Fulvio D'Acquisto
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引用次数: 0
Association of dimension-specific stressful life events with obsessive-compulsive disorder compared to social anxiety disorder 特定维度压力生活事件与强迫症与社交焦虑障碍的关联
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-01 DOI: 10.1016/j.comppsych.2024.152558
V. Hühne , S. dos Santos-Ribeiro , M.E. Moreira-de-Oliveira , L.D. Laurito , C.P. Loureiro , G.B. de Menezes , L.F. Fontenelle
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引用次数: 0
Augmentative transcranial magnetic stimulation over the left orbitofrontal cortex in patients with treatment-resistant obsessive-compulsive disorder: An acute and follow-up study 难治性强迫症患者左眼窝额叶皮质增强经颅磁刺激:一项急性和随访研究
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-01 DOI: 10.1016/j.comppsych.2024.152559
Kevin La Monica , Matteo Vismara , Sara Torriero , Beatrice Benatti , Luca Larini , Chiara Bucca , Nicolaja Girone , Monica Bosi , Bernardo Dell'Osso
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引用次数: 0
Olfactory reference syndrome: A nosological conundrum? 嗅觉参照综合征:一个病分学难题?
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-01 DOI: 10.1016/j.comppsych.2024.152555
Kayleigh Beukes , Dan J. Stein , Christine Lochner

Background

Individuals with olfactory reference syndrome (ORS) erroneously believe that they have unpleasant body odour or halitosis, often leading to compulsive washing or toothbrushing, self-consciousness, and social withdrawal [3], symptoms shared with obsessive-compulsive disorder (OCD) and social anxiety disorder (SAD) [1,2,4], respectively. ORS is classified as an ORCD, but the literature on comorbidity of ORS with OCD and SAD is sparse. We therefore examined ORS's prevalence in people with OCD and/or SAD.

Methods

In a South African clinical sample (n = 371; male = 164 [44.2 %], female = 207 [55.8 %], mean age: 32.3 [SD: 11.5 years]), ages ranging between 14 and 64 years), rates of ORS in people with primary OCD without SAD (OCD-SAD; n = 211) were compared using a chi square test with those with primary SAD without OCD (SAD-OCD; n = 118), and those with both OCD and SAD (OCD + SAD; n = 42). The study was formally approved by the research ethics committee of Stellenbosch University (reference number: 99/013). All participants provided written informed consent prior to participation in the study.

Results

In the combined dataset, ORS rates were low (n = 6/371; 1.6 %). There were significantly higher rates of comorbid ORS in the SAD-OCD group (n = 5/118; 4.2 %) compared to the OCD-SAD patients (n = 0/211; p = .005) and OCD + SAD (n = 1/42; 2.4 %; p = .022), with no significant difference between OCD-SAD and OCD + SAD (p = .677).

Conclusion

Our findings suggest a stronger link between ORS and SAD than between ORS and OCD, which may have nosological implications. Further research on the psychobiology and management of ORS may be useful in determining whether it is more closely related to SAD or to OCD.

Funding

This work has not been funded specifically. The authors are supported by the South African Medical Research Council.
嗅觉参考综合征(ORS)患者错误地认为自己有难闻的体味或口臭,往往导致强迫性洗涤或刷牙、自我意识和社交退缩,这些症状分别与强迫症(OCD)和社交焦虑症(SAD)相似[1,2,4]。ORS被归类为ORCD,但关于ORS与OCD和SAD合并症的文献很少。因此,我们检查了ORS在强迫症和/或SAD患者中的患病率。方法1例南非临床样本(n = 371;男性 = 164[44.2% %],女性 = 207[55.8% %],平均年龄:32.3 [SD: 11.5 岁]),年龄范围为14 ~ 64 岁),原发OCD无SAD患者的ORS发生率(OCD-SAD;n = 211)与原发SAD无OCD (SAD-OCD;n = 118),同时患有强迫症和SAD的患者(OCD + SAD;n = 42)。本研究得到了Stellenbosch大学研究伦理委员会的正式批准(参考编号:99/013)。所有参与者在参与研究前都提供了书面知情同意书。结果在合并数据集中,ORS率较低(n = 6/371;1.6 %)。SAD-OCD组共病ORS发生率显著高于对照组(n = 5/118;4.2 %)与OCD-SAD患者相比(n = 0/211;p = .005)和OCD + SAD (n = 1/42;2.4 %;p = .022),OCD-SAD与OCD + SAD无显著性差异(p = .677)。结论我们的研究结果表明,ORS和SAD之间的联系比ORS和OCD之间的联系更强,这可能具有分科意义。对ORS的心理生物学和管理的进一步研究可能有助于确定它与SAD还是强迫症的关系更密切。这项工作没有得到专门的资助。作者得到了南非医学研究理事会的支持。
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引用次数: 0
Do patients and clinicians agree on the essential features of OCD? 患者和临床医生是否对强迫症的基本特征达成一致?
IF 4.3 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-05-01 DOI: 10.1016/j.comppsych.2024.152557
Maria E. Moreira-de-Oliveira, Gabriela B. de Menezes, Leonardo F. Fontenelle
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引用次数: 0
期刊
Comprehensive psychiatry
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