Pub Date : 2024-01-02DOI: 10.1080/10408347.2023.2298328
Farag M A Altalbawy, Eyhab Ali, Mohammed N Fenjan, Yasser Fakri Mustafa, Sofiene Mansouri, Bokov D O, Sharipova Gulnikhol Idiyevna, Neeti Misra, Ahmed Hussien Alawadi, Ali Alsalamy
The selective and sensitive diagnosis of diseases is a significant matter in the early stages of the cure of illnesses. To elaborate, although several types of probes have been broadly applied in clinics, magnetic nanomaterials-aptamers, as new-generation probes, are becoming more and more attractive. The presence of magnetic nanomaterials brings about quantification, purification, and quantitative analysis of biomedical, especially in complex samples. Elaborately, the superparamagnetic properties and numerous functionalized groups of magnetic nanomaterials are considered two main matters for providing separation ability and immobilization substrate, respectively. In addition, the selectivity and stability of aptamer can present a high potential recognition element. Importantly, the integration of aptamer and magnetic nanomaterials benefits can boost the performance of biosensors for biomedical analysis by introducing efficient and compact probes that need low patient samples and fast diagnosis, user-friendly application, and high repeatability in the quantification of biomolecules. The primary aim of this review is to suggest a summary of the effect of the employed other types of nanomaterials in the fabrication of novel aptasensors-based magnetic nanomaterials and to carefully explore various applications of these probes in the quantification of bioagents. Furthermore, the application of these versatile and high-potential probes in terms of the detection of cancer cells and biomarkers, proteins, drugs, bacteria, and nucleoside were discussed. Besides, research gaps and restrictions in the field of biomedical analysis by magnetic nanomaterials-aptamers will be discussed.
{"title":"Aptamer-Magnetic Nanoparticle Complexes for Powerful Biosensing: A Comprehensive Review.","authors":"Farag M A Altalbawy, Eyhab Ali, Mohammed N Fenjan, Yasser Fakri Mustafa, Sofiene Mansouri, Bokov D O, Sharipova Gulnikhol Idiyevna, Neeti Misra, Ahmed Hussien Alawadi, Ali Alsalamy","doi":"10.1080/10408347.2023.2298328","DOIUrl":"https://doi.org/10.1080/10408347.2023.2298328","url":null,"abstract":"<p><p>The selective and sensitive diagnosis of diseases is a significant matter in the early stages of the cure of illnesses. To elaborate, although several types of probes have been broadly applied in clinics, magnetic nanomaterials-aptamers, as new-generation probes, are becoming more and more attractive. The presence of magnetic nanomaterials brings about quantification, purification, and quantitative analysis of biomedical, especially in complex samples. Elaborately, the superparamagnetic properties and numerous functionalized groups of magnetic nanomaterials are considered two main matters for providing separation ability and immobilization substrate, respectively. In addition, the selectivity and stability of aptamer can present a high potential recognition element. Importantly, the integration of aptamer and magnetic nanomaterials benefits can boost the performance of biosensors for biomedical analysis by introducing efficient and compact probes that need low patient samples and fast diagnosis, user-friendly application, and high repeatability in the quantification of biomolecules. The primary aim of this review is to suggest a summary of the effect of the employed other types of nanomaterials in the fabrication of novel aptasensors-based magnetic nanomaterials and to carefully explore various applications of these probes in the quantification of bioagents. Furthermore, the application of these versatile and high-potential probes in terms of the detection of cancer cells and biomarkers, proteins, drugs, bacteria, and nucleoside were discussed. Besides, research gaps and restrictions in the field of biomedical analysis by magnetic nanomaterials-aptamers will be discussed.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139080523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-02DOI: 10.1080/10408347.2023.2299280
Karen Sze Jie Tay, Hong Heng See
Sample clean-up and pre-concentration are critical components of pharmaceutical analysis. The dispersive liquid-liquid microextraction (DLLME) technique is widely recognized as the most effective approach for enhancing overall detection sensitivity. While various DLLME modes have been advanced in pharmaceutical analysis, there need to be more discussions on pre-concentration techniques specifically developed for this field. This review presents a comprehensive overview of the different DLLME modes used in pharmaceutical analysis from 2017 to May 2023. The review covers the principles of DLLME, the factors affecting microextraction, the selected applications of different DLLME modes, and their advantages and disadvantages. Additionally, it focuses on multi-extraction strategies employed for pharmaceutical analysis.
{"title":"Recent Advances in Dispersive Liquid-Liquid Microextraction for Pharmaceutical Analysis.","authors":"Karen Sze Jie Tay, Hong Heng See","doi":"10.1080/10408347.2023.2299280","DOIUrl":"https://doi.org/10.1080/10408347.2023.2299280","url":null,"abstract":"<p><p>Sample clean-up and pre-concentration are critical components of pharmaceutical analysis. The dispersive liquid-liquid microextraction (DLLME) technique is widely recognized as the most effective approach for enhancing overall detection sensitivity. While various DLLME modes have been advanced in pharmaceutical analysis, there need to be more discussions on pre-concentration techniques specifically developed for this field. This review presents a comprehensive overview of the different DLLME modes used in pharmaceutical analysis from 2017 to May 2023. The review covers the principles of DLLME, the factors affecting microextraction, the selected applications of different DLLME modes, and their advantages and disadvantages. Additionally, it focuses on multi-extraction strategies employed for pharmaceutical analysis.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139080524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bacterial and viruses pathogens are a significant hazard to human safety and health. In the imaging and detection of pathogenic microorganisms, the application of fluorescent nanoparticles is very useful. Carbon dots and quantum dots are preferred in this regard as labels, amplifiers, and/or electrode modifiers because of their outstanding features. However, precise diagnostics to identify numerous harmful bacteria simultaneously still face considerable hurdles, yet it is an inevitable issue. With the growing development of biosensors, nanoproduct-based bio-sensing has recently become one of the most promising methods for accurately identifying and quantifying various pathogens at low cost, high sensitivity, and selectivity, with time savings. The most recent applications of carbon dots in optical and electrochemical-based sensors are discussed in this review, along with some examples of pathogen sensors.HighlightsSimultaneous and early detection of pathogens is a critical issue in the management of readily spread to prevent epidemics.Carbon dots-based biosensors are more preferred in detection of pathogens due to high selectivity and sensitivity, as well as quick and cheap point-of-care platform.Summary of recent advances in the design of optical and electrochemical biosensors for the detection of pathogens.
{"title":"Carbon Dots in the Detection of Pathogenic Bacteria and Viruses.","authors":"Erhan Zor, Fariba Mollarasouli, Leyla Karadurmus, Goksu Ozcelikay, Sibel A Ozkan","doi":"10.1080/10408347.2022.2072168","DOIUrl":"10.1080/10408347.2022.2072168","url":null,"abstract":"<p><p>Bacterial and viruses pathogens are a significant hazard to human safety and health. In the imaging and detection of pathogenic microorganisms, the application of fluorescent nanoparticles is very useful. Carbon dots and quantum dots are preferred in this regard as labels, amplifiers, and/or electrode modifiers because of their outstanding features. However, precise diagnostics to identify numerous harmful bacteria simultaneously still face considerable hurdles, yet it is an inevitable issue. With the growing development of biosensors, nanoproduct-based bio-sensing has recently become one of the most promising methods for accurately identifying and quantifying various pathogens at low cost, high sensitivity, and selectivity, with time savings. The most recent applications of carbon dots in optical and electrochemical-based sensors are discussed in this review, along with some examples of pathogen sensors.HighlightsSimultaneous and early detection of pathogens is a critical issue in the management of readily spread to prevent epidemics.Carbon dots-based biosensors are more preferred in detection of pathogens due to high selectivity and sensitivity, as well as quick and cheap point-of-care platform.Summary of recent advances in the design of optical and electrochemical biosensors for the detection of pathogens.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46482592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01Epub Date: 2022-05-09DOI: 10.1080/10408347.2022.2073433
Fengjiao Li, Jinyu Zhang, Yuanzhong Wang
Many foods have both edible and medical importance and are appreciated as functional foods, preventing diseases. However, due to unscrupulous vendors and imperfect market supervision mechanisms, curative foods are prone to adulteration or some other events that harm the interests of consumers. However, traditional analytical methods are unsuitable and expensive for a broad and complex application. Therefore, people urgently need a fast, efficient, and accurate detection method to protect self-interests. Recently, the study of target samples by vibration spectrum shows strong qualitative and quantitative ability. The model established by platform technology combined with the stoichiometric analysis method can obtain better parameters, which it has good robustness and can detect functional food efficiently, quickly and nondestructive. The review compared and prospect five different vibrational spectroscopic techniques (near-infrared, Fourier transform infrared, Raman, hyperspectral imaging spectroscopy and Terahertz spectroscopy). In order to better solve some of the actual situations faced by certification, we explore and through relevant research and investigation to appropriately highlight the applicability and importance of technology combined with chemometrics in functional food authentication. There are four categories of authentication discussed: functional food authenticated in source, processing method, fraud and ingredient ratio. This paper provides an innovative process for the authentication of functional food, which has a meaningful reference value for future review or scientific research of relevant departments.
{"title":"Vibrational Spectroscopy Combined with Chemometrics in Authentication of Functional Foods.","authors":"Fengjiao Li, Jinyu Zhang, Yuanzhong Wang","doi":"10.1080/10408347.2022.2073433","DOIUrl":"10.1080/10408347.2022.2073433","url":null,"abstract":"<p><p>Many foods have both edible and medical importance and are appreciated as functional foods, preventing diseases. However, due to unscrupulous vendors and imperfect market supervision mechanisms, curative foods are prone to adulteration or some other events that harm the interests of consumers. However, traditional analytical methods are unsuitable and expensive for a broad and complex application. Therefore, people urgently need a fast, efficient, and accurate detection method to protect self-interests. Recently, the study of target samples by vibration spectrum shows strong qualitative and quantitative ability. The model established by platform technology combined with the stoichiometric analysis method can obtain better parameters, which it has good robustness and can detect functional food efficiently, quickly and nondestructive. The review compared and prospect five different vibrational spectroscopic techniques (near-infrared, Fourier transform infrared, Raman, hyperspectral imaging spectroscopy and Terahertz spectroscopy). In order to better solve some of the actual situations faced by certification, we explore and through relevant research and investigation to appropriately highlight the applicability and importance of technology combined with chemometrics in functional food authentication. There are four categories of authentication discussed: functional food authenticated in source, processing method, fraud and ingredient ratio. This paper provides an innovative process for the authentication of functional food, which has a meaningful reference value for future review or scientific research of relevant departments.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47166350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01Epub Date: 2022-10-06DOI: 10.1080/10408347.2022.2128633
Yuxin Fang, Hongen Chang, Jingrong Li, Zheng Li, Di Zhang
Rising rates of drug abuse and pharmaceutical pollution throughout the world as a consequence of increased drug production and utilization pose a serious risk to public health and to environmental integrity. It is thus critical that reliable analytical approaches to detecting drugs and their metabolites in a range of sample matrices be developed. Recent advances in the design of nanomaterial-based electrochemical sensors and biosensors have enabled promising new approaches to pharmaceutical analysis. In particular, the development of a range of novel metal nanocomposites with enhanced catalytic properties has provided a wealth of opportunities for the design of rapid and reliable platforms for the detection of specific pharmaceutical compounds. The present review provides a comprehensive overview of representative metal nanocomposites with synergistic properties and their recent (2017-2022) application in the context of electrochemical sensing as a means of detecting specific antibiotic, tuberculostatic, analgesic, antineoplastic, antipsychotic, and antihypertensive drugs. In discussing these applications, we further explore a variety of testing-related principles, fabrication approaches, characterization techniques, and parameters associated with the sensitivity and selectivity of these sensor platforms before surveying the future outlook regarding the fabrication of next-generation (bio)sensor platforms for use in pharmaceutical analysis.
{"title":"Recent Advances in Metal Nanocomposite-Based Electrochemical (Bio)Sensors for Pharmaceutical Analysis.","authors":"Yuxin Fang, Hongen Chang, Jingrong Li, Zheng Li, Di Zhang","doi":"10.1080/10408347.2022.2128633","DOIUrl":"10.1080/10408347.2022.2128633","url":null,"abstract":"<p><p>Rising rates of drug abuse and pharmaceutical pollution throughout the world as a consequence of increased drug production and utilization pose a serious risk to public health and to environmental integrity. It is thus critical that reliable analytical approaches to detecting drugs and their metabolites in a range of sample matrices be developed. Recent advances in the design of nanomaterial-based electrochemical sensors and biosensors have enabled promising new approaches to pharmaceutical analysis. In particular, the development of a range of novel metal nanocomposites with enhanced catalytic properties has provided a wealth of opportunities for the design of rapid and reliable platforms for the detection of specific pharmaceutical compounds. The present review provides a comprehensive overview of representative metal nanocomposites with synergistic properties and their recent (2017-2022) application in the context of electrochemical sensing as a means of detecting specific antibiotic, tuberculostatic, analgesic, antineoplastic, antipsychotic, and antihypertensive drugs. In discussing these applications, we further explore a variety of testing-related principles, fabrication approaches, characterization techniques, and parameters associated with the sensitivity and selectivity of these sensor platforms before surveying the future outlook regarding the fabrication of next-generation (bio)sensor platforms for use in pharmaceutical analysis.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33490986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01Epub Date: 2022-08-29DOI: 10.1080/10408347.2022.2116555
Peng Du, Jing Zhang, Jieyu Ma, Zhengkun Chu, Feng Cao, Jie Liu
Copper nanoclusters (CuNCs) as a new type of probe for environmental contaminants are gaining increasing attention because of its low cost, superior water dispersibility, wide availability and excellent optical properties. Compared with the other probes such as quantum dots and organic dyes, CuNCs show much more potential in practical application for their excellent photostability, large Stokes shift, low toxicity and other preponderance, especially in the fields of biosensing and environmental monitoring. Recently, the template-assisted synthesis of metal nanoclusters (MNCs) has been widely studied. A variety of templates such as proteins, small thiol molecules, polymers, and DNA with different spatial configuration have been used for the preparation of MNCs so far. This review primarily described recent advances in CuNCs in terms of the synthesis of CuNCs from different templates, the methods to improve the fluorescence (FL) properties of CuNCs, as well as the basic detection mechanisms based on the FL properties or catalytic properties. Finally, to promote the practical application of CuNCs probes, the challenges and prospects of CuNCs multifunctional probes are also discussed.
{"title":"Synthesis of Copper Nanoclusters and Their Application for Environmental Pollutant Probes: A Review.","authors":"Peng Du, Jing Zhang, Jieyu Ma, Zhengkun Chu, Feng Cao, Jie Liu","doi":"10.1080/10408347.2022.2116555","DOIUrl":"10.1080/10408347.2022.2116555","url":null,"abstract":"<p><p>Copper nanoclusters (CuNCs) as a new type of probe for environmental contaminants are gaining increasing attention because of its low cost, superior water dispersibility, wide availability and excellent optical properties. Compared with the other probes such as quantum dots and organic dyes, CuNCs show much more potential in practical application for their excellent photostability, large Stokes shift, low toxicity and other preponderance, especially in the fields of biosensing and environmental monitoring. Recently, the template-assisted synthesis of metal nanoclusters (MNCs) has been widely studied. A variety of templates such as proteins, small thiol molecules, polymers, and DNA with different spatial configuration have been used for the preparation of MNCs so far. This review primarily described recent advances in CuNCs in terms of the synthesis of CuNCs from different templates, the methods to improve the fluorescence (FL) properties of CuNCs, as well as the basic detection mechanisms based on the FL properties or catalytic properties. Finally, to promote the practical application of CuNCs probes, the challenges and prospects of CuNCs multifunctional probes are also discussed.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33446336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01Epub Date: 2022-05-26DOI: 10.1080/10408347.2022.2080494
Deepak Sharma, Hari Om, Ashok Kumar Sharma
Oxadiazoles, especially 1,3,4-oxadiazole scaffolds, stand among the foremost heterocyclic fragments with a broad spectrum of applications in diverse fields, including pharmacology, polymers, material science, and organic electronics, among others. In this comprehensive review, we summarize the pivotal synthetic strategies for 1,3,4-oxadiazole derivatives including dehydrogenative cyclization of 1,2-diacylhydrazines, oxidative cyclization of acylhydrazones, condensation cyclization, C-H activation of oxadiazole ring, decarboxylative cyclization and oxidative annulation along with plausible mechanisms. The set of 1,3,4-oxadiazoles selected from the literature and discussed herein epitomize the ease of synthesis as well as the possibility of linking π-conjugated groups; thereby encouraging the use of these molecules as important starting building blocks for a wide variety of fluorescent frameworks, particularly in the development of potential chemosensors. High photoluminescent quantum yield, excellent thermal and chemical stability, and the presence of potential coordination (N and O donor atoms) sites make these molecules a prominent choice for metal-ions sensors. An overview of selective metal-ion sensing, the detection limit along with the sensing mechanisms (photo-induced electron transfer, excited-state intramolecular proton transfer, and complex formation) is also included.
{"title":"Potential Synthetic Routes and Metal-Ion Sensing Applications of 1,3,4-Oxadiazoles: An Integrative Review.","authors":"Deepak Sharma, Hari Om, Ashok Kumar Sharma","doi":"10.1080/10408347.2022.2080494","DOIUrl":"10.1080/10408347.2022.2080494","url":null,"abstract":"<p><p>Oxadiazoles, especially 1,3,4-oxadiazole scaffolds, stand among the foremost heterocyclic fragments with a broad spectrum of applications in diverse fields, including pharmacology, polymers, material science, and organic electronics, among others. In this comprehensive review, we summarize the pivotal synthetic strategies for 1,3,4-oxadiazole derivatives including dehydrogenative cyclization of 1,2-diacylhydrazines, oxidative cyclization of acylhydrazones, condensation cyclization, C-H activation of oxadiazole ring, decarboxylative cyclization and oxidative annulation along with plausible mechanisms. The set of 1,3,4-oxadiazoles selected from the literature and discussed herein epitomize the ease of synthesis as well as the possibility of linking π-conjugated groups; thereby encouraging the use of these molecules as important starting building blocks for a wide variety of fluorescent frameworks, particularly in the development of potential chemosensors. High photoluminescent quantum yield, excellent thermal and chemical stability, and the presence of potential coordination (N and O donor atoms) sites make these molecules a prominent choice for metal-ions sensors. An overview of selective metal-ion sensing, the detection limit along with the sensing mechanisms (photo-induced electron transfer, excited-state intramolecular proton transfer, and complex formation) is also included.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46470381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In today's world, Parkinson's disease (PD) has been introduced as a long-term degenerative disorder of the central nervous system which mainly affects approximately more than ten million people worldwide. The vast majority of diagnostic methods for PD have operated based on conventional sensing platforms, while the traditional laboratory tests are not efficient for diagnosis of PD in the early stage due to symptoms of this common neurodegenerative syndrome starting slowly. The advent of the aptasensor has revolutionized the early-stage diagnosis of PD by measuring related biomarkers due to the myriad advantages of originating from aptamers which can be able to sensitive and selective capture various types of related biomarkers. The progress of numerous sensing platforms and methodologies in terms of biosensors based on aptamer application for PD diagnosis has revealed promising results. In this review, we present the latest developments in myriad types of aptasensors for the determination of related PD biomarkers. Working strategies, advantages and limitations of these sensing approaches are also mentioned, followed by prospects and challenges.
{"title":"Current Progress in Aptasensor for Ultra-Low Level Monitoring of Parkinson's Disease Biomarkers.","authors":"Ria Margiana, Ali Thaeer Hammid, Irfan Ahmad, Fahad Alsaikhan, Abduladheem Turki Jalil, Farkhod Tursunbaev, Fadilah Umar, Rosario Mireya Romero Parra, Yasser Fakri Mustafa","doi":"10.1080/10408347.2022.2091920","DOIUrl":"10.1080/10408347.2022.2091920","url":null,"abstract":"<p><p>In today's world, Parkinson's disease (PD) has been introduced as a long-term degenerative disorder of the central nervous system which mainly affects approximately more than ten million people worldwide. The vast majority of diagnostic methods for PD have operated based on conventional sensing platforms, while the traditional laboratory tests are not efficient for diagnosis of PD in the early stage due to symptoms of this common neurodegenerative syndrome starting slowly. The advent of the aptasensor has revolutionized the early-stage diagnosis of PD by measuring related biomarkers due to the myriad advantages of originating from aptamers which can be able to sensitive and selective capture various types of related biomarkers. The progress of numerous sensing platforms and methodologies in terms of biosensors based on aptamer application for PD diagnosis has revealed promising results. In this review, we present the latest developments in myriad types of aptasensors for the determination of related PD biomarkers. Working strategies, advantages and limitations of these sensing approaches are also mentioned, followed by prospects and challenges.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40400278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01Epub Date: 2022-10-13DOI: 10.1080/10408347.2022.2132374
Ya-Ling An, Wen-Long Wei, De-An Guo
Medicinal plants of Fritillaria are widely distributed in numerous countries around the world and possess excellent antitussive and expectorant effects. In particular, Fritillariae Bulbus (FB) as a precious traditional medicine has thousands of years of medical history in China. Herbs of Fritillaria have a high market value and demand while limited by harsh growing circumstances and scarce wild resources. As a consequence, fraudulent behaviors are regularly engaged by the unscrupulous merchants in an attempt to reap greater profits. It is of an urgent need to evaluate the quality of Fritillaria herbs and their products using various analytical instruments and techniques. This review has scrutinized approximately 160 articles from 1995 to 2022 published on the investigation of Fritillaria herbs and related herbal products. The botanical classification of genus Fritillaria, types of counterfeits, technologies applied for differentiating Fritillaria species were comprehensively summarized and discussed in the current review. Molecular and chromatographic identification were the dominant technologies in the authentication of Fritillaria herbs. Additionally, we brought some potential and promising technologies and analytical strategies into attention, which are worthy attempting in the future researches. This review could conduce to excellent reference value for further investigations of the authenticity assessment of Fritillaria species.
{"title":"Application of Analytical Technologies in the Discrimination and Authentication of Herbs from Fritillaria: A Review.","authors":"Ya-Ling An, Wen-Long Wei, De-An Guo","doi":"10.1080/10408347.2022.2132374","DOIUrl":"10.1080/10408347.2022.2132374","url":null,"abstract":"<p><p>Medicinal plants of Fritillaria are widely distributed in numerous countries around the world and possess excellent antitussive and expectorant effects. In particular, Fritillariae Bulbus (FB) as a precious traditional medicine has thousands of years of medical history in China. Herbs of Fritillaria have a high market value and demand while limited by harsh growing circumstances and scarce wild resources. As a consequence, fraudulent behaviors are regularly engaged by the unscrupulous merchants in an attempt to reap greater profits. It is of an urgent need to evaluate the quality of Fritillaria herbs and their products using various analytical instruments and techniques. This review has scrutinized approximately 160 articles from 1995 to 2022 published on the investigation of Fritillaria herbs and related herbal products. The botanical classification of genus Fritillaria, types of counterfeits, technologies applied for differentiating Fritillaria species were comprehensively summarized and discussed in the current review. Molecular and chromatographic identification were the dominant technologies in the authentication of Fritillaria herbs. Additionally, we brought some potential and promising technologies and analytical strategies into attention, which are worthy attempting in the future researches. This review could conduce to excellent reference value for further investigations of the authenticity assessment of Fritillaria species.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33503233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01Epub Date: 2022-10-20DOI: 10.1080/10408347.2022.2131374
Henry MacKeown, Barbara Benedetti, Chiara Scapuzzi, Marina Di Carro, Emanuele Magi
The membranes in polar organic chemical integrative samplers (POCIS) enclose the receiving sorbent and protect it from coming into direct contact with the environmental matrix. They have a crucial role in extending the kinetic regime of contaminant uptake, by slowing down their diffusion between the water phase and the receiving phase. The drive to improve passive sampling requires membranes with better design and enhanced performances. In this review, the preparation of standard polyethersulfone (PES) membranes for POCIS is presented, as well as methods to evaluate their composition, morphology, structure, and performance. Generally, only supplier-related morphological and structural data are provided, such as membrane type, thickness, surface area, and pore diameter. The issues related to the use of PES membranes in POCIS applications are exposed. Finally, alternative membranes to PES in POCIS are also discussed, although no better membrane has yet been developed. This review highlights the urge for more membrane characterization details and a better comprehension of the mechanisms which underlay their behavior and performance, to improve membrane selection and optimize passive sampler development.
极性有机化学综合采样器(POCIS)中的膜将接收吸附剂封闭起来,防止其与环境基质直接接触。它们通过减缓污染物在水相和接收相之间的扩散,在延长污染物吸收动力学机制方面发挥着至关重要的作用。改进被动采样需要设计更好、性能更强的膜。本综述介绍了用于 POCIS 的标准聚醚砜(PES)膜的制备方法,以及评估其成分、形态、结构和性能的方法。一般来说,只提供与供应商相关的形态和结构数据,如膜类型、厚度、表面积和孔径。与在 POCIS 应用中使用聚醚砜膜有关的问题也暴露无遗。最后,还讨论了 POCIS 中 PES 的替代膜,尽管目前还没有开发出更好的膜。这篇综述强调了需要更多的膜特性细节和更好地理解其行为和性能的机制,以改进膜的选择和优化被动采样器的开发。
{"title":"A Review on Polyethersulfone Membranes in Polar Organic Chemical Integrative Samplers: Preparation, Characterization and Innovation.","authors":"Henry MacKeown, Barbara Benedetti, Chiara Scapuzzi, Marina Di Carro, Emanuele Magi","doi":"10.1080/10408347.2022.2131374","DOIUrl":"10.1080/10408347.2022.2131374","url":null,"abstract":"<p><p>The membranes in polar organic chemical integrative samplers (POCIS) enclose the receiving sorbent and protect it from coming into direct contact with the environmental matrix. They have a crucial role in extending the kinetic regime of contaminant uptake, by slowing down their diffusion between the water phase and the receiving phase. The drive to improve passive sampling requires membranes with better design and enhanced performances. In this review, the preparation of standard polyethersulfone (PES) membranes for POCIS is presented, as well as methods to evaluate their composition, morphology, structure, and performance. Generally, only supplier-related morphological and structural data are provided, such as membrane type, thickness, surface area, and pore diameter. The issues related to the use of PES membranes in POCIS applications are exposed. Finally, alternative membranes to PES in POCIS are also discussed, although no better membrane has yet been developed. This review highlights the urge for more membrane characterization details and a better comprehension of the mechanisms which underlay their behavior and performance, to improve membrane selection and optimize passive sampler development.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":4.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40645490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}