Pub Date : 2024-04-24DOI: 10.1080/10408347.2024.2339968
Jari S Algethami, H. M. Al-Saidi, E. H. Alosaimi, Yaser A Alnaam, K. Al-Ahmary, Sikandar Khan
In recent decades, heavy metal ions have emerged as a significant global environmental concern, posing threats to the delicate balance of ecosystems worldwide. Their introduction into ecosystems occurs through various activities and poses a serious risk to human health. Among heavy metal ions, Cd2+ is recognized as a highly toxic pollutant. Its widespread use contributes to its accumulation in the environment. Chronic exposure to Cd2+ ions present serious risks to both the environment and human health. Therefore, the detection of these metal ions are very important. Organic fluorometric and colorimetric detection have emerged as promising tools for this purpose, offering advantages such as high sensitivity, selectivity, and sometimes reversibility. This review offers a comprehensive overview of the recent advancements in the fluorometric and colorimetric detection of Cd2+ using organic chemosensors from 2019 to 2024. We delve into key aspects of these studies, including the design strategies employed to design novel chemosensors and the underlying sensing mechanisms. Furthermore, we explore the diverse applications of these organic chemosensors, ranging from environmental monitoring to biomedical diagnostics. By analyzing the latest research findings, this review aims to offer insights into the current state-of-the-art in the field of Cd2+ detection using organic chemosensors. Additionally, it highlights the potential opportunities and challenges that lie ahead, paving the way for future advancements in this important area of research.
{"title":"Recent Advancements in Fluorometric and Colorimetric Detection of Cd2+ Using Organic Chemosensors: A Review (2019-2024).","authors":"Jari S Algethami, H. M. Al-Saidi, E. H. Alosaimi, Yaser A Alnaam, K. Al-Ahmary, Sikandar Khan","doi":"10.1080/10408347.2024.2339968","DOIUrl":"https://doi.org/10.1080/10408347.2024.2339968","url":null,"abstract":"In recent decades, heavy metal ions have emerged as a significant global environmental concern, posing threats to the delicate balance of ecosystems worldwide. Their introduction into ecosystems occurs through various activities and poses a serious risk to human health. Among heavy metal ions, Cd2+ is recognized as a highly toxic pollutant. Its widespread use contributes to its accumulation in the environment. Chronic exposure to Cd2+ ions present serious risks to both the environment and human health. Therefore, the detection of these metal ions are very important. Organic fluorometric and colorimetric detection have emerged as promising tools for this purpose, offering advantages such as high sensitivity, selectivity, and sometimes reversibility. This review offers a comprehensive overview of the recent advancements in the fluorometric and colorimetric detection of Cd2+ using organic chemosensors from 2019 to 2024. We delve into key aspects of these studies, including the design strategies employed to design novel chemosensors and the underlying sensing mechanisms. Furthermore, we explore the diverse applications of these organic chemosensors, ranging from environmental monitoring to biomedical diagnostics. By analyzing the latest research findings, this review aims to offer insights into the current state-of-the-art in the field of Cd2+ detection using organic chemosensors. Additionally, it highlights the potential opportunities and challenges that lie ahead, paving the way for future advancements in this important area of research.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140664940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-24DOI: 10.1080/10408347.2024.2343854
Untika Pengsomjit, Fatima Alabdo, C. Karuwan, Charoenkwan Kraiya, Waleed Alahmad, S. A. Ozkan
Graphene, renowned for its exceptional physicochemical attributes, has emerged as a favored substrate for integrating a wide array of inorganic and organic materials in scientific endeavors and innovations. Electrochemical graphene-based nanocomposite sensors have been developed by incorporating diverse nanoparticles into graphene, effectively immobilized onto electrodes through various techniques. These graphene-based nanocomposite sensors have effectively detected and quantified various electroactive species in samples. This review delves into using graphene nanocomposites to fabricate electrochemical sensors, leveraging the exceptional electrical, mechanical, and thermal properties inherent to graphene derivatives. These nanocomposites showcase electrocatalytic activity, substantial surface area, superior electrical conductivity, adsorption capabilities, and notable porosity, which are highly advantageous for sensing applications. A myriad of characterization techniques, including Raman spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), BET surface area analysis, and X-ray diffraction (XRD), have proven effective in exploring the properties of graphene nanocomposites and validating the adjustable formation of these nanomaterials with graphene. The applicability of these sensors across various matrices, encompassing environmental, food, and biological domains, has been evaluated through electrochemical measurements, such as cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV). This review provides a comprehensive overview of synthesis methods, characterization techniques, and sensor applications pertinent to graphene-based nanocomposites. Furthermore, it deliberates on the challenges and future prospects within this burgeoning field.
{"title":"Innovative Graphene-Based Nanocomposites for Improvement of Electrochemical Sensors: Synthesis, Characterization, and Applications.","authors":"Untika Pengsomjit, Fatima Alabdo, C. Karuwan, Charoenkwan Kraiya, Waleed Alahmad, S. A. Ozkan","doi":"10.1080/10408347.2024.2343854","DOIUrl":"https://doi.org/10.1080/10408347.2024.2343854","url":null,"abstract":"Graphene, renowned for its exceptional physicochemical attributes, has emerged as a favored substrate for integrating a wide array of inorganic and organic materials in scientific endeavors and innovations. Electrochemical graphene-based nanocomposite sensors have been developed by incorporating diverse nanoparticles into graphene, effectively immobilized onto electrodes through various techniques. These graphene-based nanocomposite sensors have effectively detected and quantified various electroactive species in samples. This review delves into using graphene nanocomposites to fabricate electrochemical sensors, leveraging the exceptional electrical, mechanical, and thermal properties inherent to graphene derivatives. These nanocomposites showcase electrocatalytic activity, substantial surface area, superior electrical conductivity, adsorption capabilities, and notable porosity, which are highly advantageous for sensing applications. A myriad of characterization techniques, including Raman spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), BET surface area analysis, and X-ray diffraction (XRD), have proven effective in exploring the properties of graphene nanocomposites and validating the adjustable formation of these nanomaterials with graphene. The applicability of these sensors across various matrices, encompassing environmental, food, and biological domains, has been evaluated through electrochemical measurements, such as cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV). This review provides a comprehensive overview of synthesis methods, characterization techniques, and sensor applications pertinent to graphene-based nanocomposites. Furthermore, it deliberates on the challenges and future prospects within this burgeoning field.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140665687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-22DOI: 10.1080/10408347.2024.2336981
M. M. Hurkul, Ahmet Cetinkaya, S. Kaya, Seyda Yayla, S. A. Ozkan
The escalating costs of healthcare services and a growing awareness of personal health responsibilities have led individuals to explore natural methods alongside conventional medicines for health improvement and disease prevention. The aging global population is experiencing increased health needs, notably related to conditions like diabetes, heart disease, and hypertension. Lifestyle-related diseases, poor dietary habits, and sedentary lifestyles underscore the importance of foods containing nutrients that can aid in preventing and managing these diseases. Phenolic compounds, a fundamental group of phytochemicals, are prominent in the chemical diversity of the natural world and are abundant in functional foods. Widely distributed in various plant parts, these compounds exhibit important functional and sensory properties, including color, taste, and aroma. Their diverse functionalities, particularly antioxidant activity, play a crucial role in mitigating cellular oxidative stress, potentially reducing damage associated with serious health issues such as cardiovascular disease, neurodegenerative disea23ses, and cancer. Phenolic compounds exist in different forms, some combined with glycosides, impacting their biological effects and absorption. Approximately 8000 polyphenols isolated from plants offer significant potential for natural medicines and nutritional supplements. Therefore, their extraction process and selective and sensitive food determination are very important. This review focuses on the extraction processes, analytical methods, and health effects of major phenolic compounds in foods. The examination encompasses a comprehensive analysis of analytical approaches and their applications in elucidating the presence and impact of these compounds on human health.
{"title":"Investigation of Health Effects of Major Phenolic Compounds in Foods: Extraction Processes, Analytical Approaches and Applications.","authors":"M. M. Hurkul, Ahmet Cetinkaya, S. Kaya, Seyda Yayla, S. A. Ozkan","doi":"10.1080/10408347.2024.2336981","DOIUrl":"https://doi.org/10.1080/10408347.2024.2336981","url":null,"abstract":"The escalating costs of healthcare services and a growing awareness of personal health responsibilities have led individuals to explore natural methods alongside conventional medicines for health improvement and disease prevention. The aging global population is experiencing increased health needs, notably related to conditions like diabetes, heart disease, and hypertension. Lifestyle-related diseases, poor dietary habits, and sedentary lifestyles underscore the importance of foods containing nutrients that can aid in preventing and managing these diseases. Phenolic compounds, a fundamental group of phytochemicals, are prominent in the chemical diversity of the natural world and are abundant in functional foods. Widely distributed in various plant parts, these compounds exhibit important functional and sensory properties, including color, taste, and aroma. Their diverse functionalities, particularly antioxidant activity, play a crucial role in mitigating cellular oxidative stress, potentially reducing damage associated with serious health issues such as cardiovascular disease, neurodegenerative disea23ses, and cancer. Phenolic compounds exist in different forms, some combined with glycosides, impacting their biological effects and absorption. Approximately 8000 polyphenols isolated from plants offer significant potential for natural medicines and nutritional supplements. Therefore, their extraction process and selective and sensitive food determination are very important. This review focuses on the extraction processes, analytical methods, and health effects of major phenolic compounds in foods. The examination encompasses a comprehensive analysis of analytical approaches and their applications in elucidating the presence and impact of these compounds on human health.","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140677631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Glucose concentration is a crucial parameter for assessing human health. Over recent years, non-enzymatic electrochemical glucose sensors have drawn considerable attention due to their substantial ...
葡萄糖浓度是评估人体健康的一个重要参数。近年来,非酶电化学葡萄糖传感器因其巨大的潜力而备受关注。
{"title":"Advances of Transition Metal-Based Electrochemical Non-enzymatic Glucose Sensors for Glucose Analysis: A Review","authors":"Haotian Li, Nan Xiao, Mengyi Jiang, Jianjun Long, Zhanhong Li, Zhigang Zhu","doi":"10.1080/10408347.2024.2339955","DOIUrl":"https://doi.org/10.1080/10408347.2024.2339955","url":null,"abstract":"Glucose concentration is a crucial parameter for assessing human health. Over recent years, non-enzymatic electrochemical glucose sensors have drawn considerable attention due to their substantial ...","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140626698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-17DOI: 10.1080/10408347.2024.2339962
Ahmet Cetinkaya, S. Irem Kaya, Fatma Budak, Sibel A Ozkan
Ovarian cancer, which affects the female reproductive organs, is one of the most common types of cancer. Since this type of cancer has a high mortality rate from gynaecological cancers, the scienti...
{"title":"Current Analytical Methods for the Sensitive Assay of New-Generation Ovarian Cancer Drugs in Pharmaceutical and Biological Samples","authors":"Ahmet Cetinkaya, S. Irem Kaya, Fatma Budak, Sibel A Ozkan","doi":"10.1080/10408347.2024.2339962","DOIUrl":"https://doi.org/10.1080/10408347.2024.2339962","url":null,"abstract":"Ovarian cancer, which affects the female reproductive organs, is one of the most common types of cancer. Since this type of cancer has a high mortality rate from gynaecological cancers, the scienti...","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140615240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-09DOI: 10.1080/10408347.2024.2337876
Umer Shahzad, Mohsin Saeed, Hadi M. Marwani, Jehan Y. Al-Humaidi, Shujah ur Rehman, Raed H. Althomali, Md. Rabiul Awual, Mohammed M. Rahman
Electrochemical sensors have been the subject of much research and development as of late, with several publications detailing new designs boasting enhanced performance metrics. That is, without a ...
{"title":"Recent Progress on Potentiometric Sensor Applications Based on Nanoscale Metal Oxides: A Comprehensive Review","authors":"Umer Shahzad, Mohsin Saeed, Hadi M. Marwani, Jehan Y. Al-Humaidi, Shujah ur Rehman, Raed H. Althomali, Md. Rabiul Awual, Mohammed M. Rahman","doi":"10.1080/10408347.2024.2337876","DOIUrl":"https://doi.org/10.1080/10408347.2024.2337876","url":null,"abstract":"Electrochemical sensors have been the subject of much research and development as of late, with several publications detailing new designs boasting enhanced performance metrics. That is, without a ...","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140578508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In recent years, the field of Supramolecular Chemistry has witnessed tremendous progress owing to the development of versatile optical sensors for the detection of harmful biological analytes. Nitr...
近年来,由于用于检测有害生物分析物的多功能光学传感器的开发,超分子化学领域取得了巨大进步。硝...
{"title":"Recent Advancements and Future Prospects in NBD-Based Fluorescent Chemosensors: Design Strategy, Sensing Mechanism, and Biological Applications","authors":"Gurdeep Kaur, Richa Rani, Jeevika Raina, Iqubal Singh","doi":"10.1080/10408347.2024.2337869","DOIUrl":"https://doi.org/10.1080/10408347.2024.2337869","url":null,"abstract":"In recent years, the field of Supramolecular Chemistry has witnessed tremendous progress owing to the development of versatile optical sensors for the detection of harmful biological analytes. Nitr...","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140602507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A living cell is a complex network of molecular, biochemical and physiological processes. Cellular activities, such as ion transport, metabolic processes, and cell-cell interactions can be determined electrochemically by detecting the electrons or ions exchanged in these processes. Electrochemical methods often are noninvasive, and they can enable the real-time monitoring of cellular processes. Scanning electrochemical microscopy (SECM) is an advanced scanning probe electroanalysis technique that can map the surface topography and local reactivity of a substrate with high precision at the micro- or nanoscale. By measuring electrochemical signals, such as redox reactions, ion fluxes, and pH changes, SECM can provide valuable insights into cellular activity. As a result of its compatibility with liquid medium measurements and its nondestructive nature, SECM has gained popularity in living cell research. This review aims to furnish an overview of SECM, elucidating its principles, applications, and its potential to contribute significantly to advancements in cell biology, electroporation, and biosensors. As a multidisciplinary tool, SECM is distinguished by its ability to unravel the intricacies of living cells and offers promising avenues for breakthroughs in our understanding of cellular complexity.
{"title":"Exploring the Living Cell: Applications and Advances of Scanning Electrochemical Microscopy.","authors":"Margarita Poderyte, Arunas Ramanavicius, Aušra Valiūnienė","doi":"10.1080/10408347.2024.2328135","DOIUrl":"https://doi.org/10.1080/10408347.2024.2328135","url":null,"abstract":"<p><p>A living cell is a complex network of molecular, biochemical and physiological processes. Cellular activities, such as ion transport, metabolic processes, and cell-cell interactions can be determined electrochemically by detecting the electrons or ions exchanged in these processes. Electrochemical methods often are noninvasive, and they can enable the real-time monitoring of cellular processes. Scanning electrochemical microscopy (SECM) is an advanced scanning probe electroanalysis technique that can map the surface topography and local reactivity of a substrate with high precision at the micro- or nanoscale. By measuring electrochemical signals, such as redox reactions, ion fluxes, and pH changes, SECM can provide valuable insights into cellular activity. As a result of its compatibility with liquid medium measurements and its nondestructive nature, SECM has gained popularity in living cell research. This review aims to furnish an overview of SECM, elucidating its principles, applications, and its potential to contribute significantly to advancements in cell biology, electroporation, and biosensors. As a multidisciplinary tool, SECM is distinguished by its ability to unravel the intricacies of living cells and offers promising avenues for breakthroughs in our understanding of cellular complexity.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140335082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-20DOI: 10.1080/10408347.2024.2325129
Sofian Kanan, Khaled Obeideen, Matthew Moyet, Heba Abed, Danyah Khan, Aysha Shabnam, Yehya El-Sayed, Mahreen Arooj, Ahmed A Mohamed
Optimizing materials and associated structures for detecting various environmental gas pollutant concentrations has been a major challenge in environmental sensing technology. Semiconducting metal ...
优化用于检测各种环境气体污染物浓度的材料和相关结构一直是环境传感技术的一大挑战。半导体金属...
{"title":"Recent Advances on Metal Oxide Based Sensors for Environmental Gas Pollutants Detection","authors":"Sofian Kanan, Khaled Obeideen, Matthew Moyet, Heba Abed, Danyah Khan, Aysha Shabnam, Yehya El-Sayed, Mahreen Arooj, Ahmed A Mohamed","doi":"10.1080/10408347.2024.2325129","DOIUrl":"https://doi.org/10.1080/10408347.2024.2325129","url":null,"abstract":"Optimizing materials and associated structures for detecting various environmental gas pollutant concentrations has been a major challenge in environmental sensing technology. Semiconducting metal ...","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140171025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-18DOI: 10.1080/10408347.2024.2328104
Yongming Guo, Yijin Li, Yubin Xiang
Vitamin B12 plays a significant role in maintaining human health. Deficiency or excess intake of vitamin B12 may cause some diseases. Therefore, it is significant to fabricate sensors for sensitive assay of vitamin B12. In the past few years, a variety of nanomaterials have been developed for the fluorescence detection of vitamin B12 in tablets, injection, human serum and food. In the review, the assay mechanisms of fluorescent nanomaterials for sensing vitamin B12 were first briefly discussed. And the progress of various nanomaterials for fluorescence detection of vitamin B12 were systematically summarized. Furthermore, the sensing performance of fluorescent nanosensors was compared with fluorescent probes. Lastly, the challenges and perspectives about the topic were presented.
{"title":"Advances in Fluorescent Nanosensors for Detection of Vitamin B<sub>12</sub>.","authors":"Yongming Guo, Yijin Li, Yubin Xiang","doi":"10.1080/10408347.2024.2328104","DOIUrl":"https://doi.org/10.1080/10408347.2024.2328104","url":null,"abstract":"<p><p>Vitamin B<sub>12</sub> plays a significant role in maintaining human health. Deficiency or excess intake of vitamin B<sub>12</sub> may cause some diseases. Therefore, it is significant to fabricate sensors for sensitive assay of vitamin B<sub>12</sub>. In the past few years, a variety of nanomaterials have been developed for the fluorescence detection of vitamin B<sub>12</sub> in tablets, injection, human serum and food. In the review, the assay mechanisms of fluorescent nanomaterials for sensing vitamin B<sub>12</sub> were first briefly discussed. And the progress of various nanomaterials for fluorescence detection of vitamin B<sub>12</sub> were systematically summarized. Furthermore, the sensing performance of fluorescent nanosensors was compared with fluorescent probes. Lastly, the challenges and perspectives about the topic were presented.</p>","PeriodicalId":10744,"journal":{"name":"Critical reviews in analytical chemistry","volume":null,"pages":null},"PeriodicalIF":5.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140157748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}