Pub Date : 2024-01-03DOI: 10.2174/0115748855270408230925073813
Rohit Malhotra, Louis Cojandaraj
Nitophyllum marginale holds potential for medical applications due to its bioactive compounds, making it promising for developing new therapeutic interventions. Our study aims to evaluate the bioactivity of Nitophyllum marginale extracts obtained using methanol and chloroform solvents. We focus on analyzing the phytochemical profile, antioxidant activity, and antidiabetic potential of seaweed extract in this study. By examining the medicinal properties of Nitophyllum marginale, we aim to explore the therapeutic bioactivity potentiality and its prime role in improvising and searching for potential alternatives for seizing Diabetes mellitus. The antioxidant activity of Nitophyllum marginale was evaluated using ABTS, DPPH, nitric oxide, lipid peroxidation, and hydrogen peroxide assays. Additionally, alphaglucosidase inhibition tests were conducted to evaluate the potential as an antidiabetic agent. The study revealed that extracts from Nitophyllum marginale contain antioxidants that protect cells from oxidative stress. These extracts also contain bioactive compounds like alkaloids, flavonoids, phenols, saponins, and carbohydrates. These compounds work together to provide antioxidant benefits. Additionally, the extracts showed activity against alpha-glucosidase, which is vital for managing blood sugar levels. These results emphasize the existence of bioactive metabolites exhibiting phytochemicals, antioxidants, and antidiabetic activities obtained from the extract using chloroform and methanol solvents. These findings suggest the potential of Nitophyllum marginale extracts as a natural reservoir of antioxidants and antidiabetic agents.
{"title":"Evaluation of Phytochemicals, Antioxidants, and Antidiabetic Activity of\u0000Nitophyllum marginale by Using Analytical Approaches","authors":"Rohit Malhotra, Louis Cojandaraj","doi":"10.2174/0115748855270408230925073813","DOIUrl":"https://doi.org/10.2174/0115748855270408230925073813","url":null,"abstract":"\u0000\u0000Nitophyllum marginale holds potential for medical applications due to its\u0000bioactive compounds, making it promising for developing new therapeutic interventions. Our study\u0000aims to evaluate the bioactivity of Nitophyllum marginale extracts obtained using methanol and\u0000chloroform solvents. We focus on analyzing the phytochemical profile, antioxidant activity, and antidiabetic\u0000potential of seaweed extract in this study. By examining the medicinal properties\u0000of Nitophyllum marginale, we aim to explore the therapeutic bioactivity potentiality and its prime\u0000role in improvising and searching for potential alternatives for seizing Diabetes mellitus.\u0000\u0000\u0000\u0000The antioxidant activity of Nitophyllum marginale was evaluated using ABTS,\u0000DPPH, nitric oxide, lipid peroxidation, and hydrogen peroxide assays. Additionally, alphaglucosidase\u0000inhibition tests were conducted to evaluate the potential as an antidiabetic agent.\u0000\u0000\u0000\u0000The study revealed that extracts from Nitophyllum marginale contain antioxidants that protect\u0000cells from oxidative stress. These extracts also contain bioactive compounds like alkaloids, flavonoids,\u0000phenols, saponins, and carbohydrates. These compounds work together to provide antioxidant\u0000benefits. Additionally, the extracts showed activity against alpha-glucosidase, which is vital for\u0000managing blood sugar levels.\u0000\u0000\u0000\u0000These results emphasize the existence of bioactive metabolites exhibiting phytochemicals,\u0000antioxidants, and antidiabetic activities obtained from the extract using chloroform and methanol\u0000solvents. These findings suggest the potential of Nitophyllum marginale extracts as a natural\u0000reservoir of antioxidants and antidiabetic agents.\u0000","PeriodicalId":11004,"journal":{"name":"Current Drug Therapy","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139388447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}