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THE ROLE OF RLM AND AVRLM GENES IN THE REALIZATION OF RAPE SPECIFIC RESISTANCE TO BLACKLEG RLM和avrlm基因在油菜黑腿特异性抗性实现中的作用
Pub Date : 2018-05-20 DOI: 10.29235/1561-8323-2018-62-2-203-209
V. Lemesh, G. Mozgova, Yadviga E. Pilyuk, N. E. Horuzhiy, E. S. Byk, A. Burakova
As part of the study, DNA markers for local races L. maculans were identified and found that the AvrLm4-7 sequence in the selected fungus population is specifically recognized by the resistance Rlm4 and Rlm7 genes. The SCAR marker BN204 was identified, which allows us to identify homozygous and heterozygous plants carrying the Rlm4 gene. The work collection, including 22 varieties and 39 hybrids of rape, was analyzed using the DNA marker BN204. PCR results allowed us to establish that the number of individual plants with the resistance Rlm4 gene was higher than the number of stable forms characterized by the infection of leaf explants with pathogen races carrying the AvrLm4-7 sequence. It is supposed that these individual plants contain the Rlm4 gene, but they lack the Rlm7 gene.
作为研究的一部分,我们对当地菌种L. maculans的DNA标记进行了鉴定,发现所选真菌群体中的avrl4 -7序列被抗性基因Rlm4和Rlm7特异性识别。鉴定出SCAR标记BN204,使我们能够鉴定携带Rlm4基因的纯合子和杂合子植物。利用DNA标记BN204对油菜22个品种和39个杂交种进行分析。PCR结果表明,具有抗性Rlm4基因的单株数量高于携带avrl4 -7序列的病原菌小种侵染叶片外植体的稳定株数量。据推测,这些单株植物含有Rlm4基因,但缺乏Rlm7基因。
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引用次数: 0
HALOGENESIS IN THE PRIPYAT PALEORIFT pripyat古裂谷的卤化作用
Pub Date : 2018-05-20 DOI: 10.29235/1561-8323-2018-62-2-228-235
А. В. Кудельский
The problem of halogenesis in the Pripyat intercontinental paleorift is considered for the first time in a new fashion. At least, three periods of existence of arid climate and evaporate basins of seawater condensation within paleorift boundaries have been established. However, in none of them the concentration of water reached the salinity degree, at which the precipitation of rock salt begins. The intense halogenesis and accumulation of thick salt formations took place at the early (D 3 2 lv–D 3 2 dm) and mature (D 3 2 lb–D 3 2 or) stages of development of rift graben and explosive volcanism within it; this testifies to a close genetic relationship between these two phenomena.
本文首次以一种新的方式讨论了普里皮亚季洲际古裂谷的盐生问题。至少确定了古裂谷边界内存在的三个时期的干旱气候和海水凝结蒸发盆地。然而,在这些地方,水的浓度都没有达到岩盐开始沉淀的含盐量。在裂谷地堑发育的早期(d32lb - d32dm)和成熟阶段(d32lb - d32or),裂谷地堑内爆发火山作用形成强烈的卤化作用和厚盐层的聚集;这证明这两种现象之间有密切的遗传关系。
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引用次数: 0
ЗАВИСИМОСТЬ ЭКСПРЕССИИ ГЕНОВ, КОНТРОЛИРУЮЩИХ ФУНКЦИОНИРОВАНИЕ БРАССИНОСТЕРОИДОВ И ЭТИЛЕНА В КЛЕТКАХ РАСТЕНИЙ ТОМАТА, ОТ ГРАВИСТИМУЛЯЦИИ ИХ ВЕРХУШЕЧНЫХ ЛИСТЬЕВ 控制番茄植物细胞中brsno类固醇和乙烯功能的基因表达依赖于叶片的引力刺激。
Pub Date : 2018-05-20 DOI: 10.29235/1561-8323-2018-62-2-193-202
S. V. Sukhaveyeva, A. M. Каbachevskay, N. A. Radtsevich, I. D. Volotovski
The influence of gravistimulation on the gene expression level in tomato leaf cells at early (15 minutes – 3 hours) and late (more than 3 hours – 24 hours) stages of the gravitropic response was assessed. The sensitivity of expression of genes coding proteins associated with brassinosteroid and ethylene functioning was determined using real-time RT-PCR. The pre-treatment of tomato plants with ethephon (the source of exogenous ethylene) led to an increase in the relative level of expression of the investigated genes under gravistimulation in the plants.
研究了重力刺激对番茄叶片细胞在向地性反应早期(15分钟- 3小时)和后期(超过3小时- 24小时)基因表达水平的影响。利用实时RT-PCR技术测定油菜素内酯和乙烯功能相关基因编码蛋白表达的敏感性。用乙烯利(外源乙烯的来源)预处理番茄植株后,这些基因在重力刺激下的相对表达量增加。
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引用次数: 0
ОТДАЛЕННЫЕ РЕЗУЛЬТАТЫ ЛЕЧЕНИЯ РАКА ЭНДОМЕТРИЯ ВЫСОКОГО РИСКА I СТАДИИ В ЗАВИСИМОСТИ ОТ МОРФОЛОГИЧЕСКОГО ТИПА ОПУХОЛИ 高风险内分泌癌治疗的长期结果,取决于肿瘤的形态类型。
Pub Date : 2018-05-20 DOI: 10.29235/1561-8323-2018-62-2-217-227
S. A. Krasny, S. Mavrichev, A. Evmenenko, S. Taranenko
The work is devoted to the study of the long-term results of treatment and the effect of adjuvant chemotherapy on the survival of patients with endometrial cancer (EC) of high-risk stage I, depending on the histological tumor type. The study included 225 patients with endometrial cancers of the IBG1 stage and nonendometrioid stage I cancer (serous, clear cell, undifferentiated carcinoma, carcinosarcomama) who received treatment in Belarus in 2006–2010. The overall (OS), cancerspecific (CSS) and disease-free (DFS) 5-year survival in high-risk EC was 66.7 ± 3.2, 77.4 ± 2.9 and 77.0 ± 2.9 % 10-year-old – 53.7 ± 4.5, 69.7 ± 4.2 and 69.3 ± 4.2 % respectively. There were no statistically significant differences in the survival, depending on the morphological tumor type, but the endometrioid carcinoma of the IBG3 stage is defined as the most favorable form of the high-risk EC, and the undifferentiated carcinoma and carcinosarcoma are the most unfavorable forms. There were no statistically significant differences in OS, CSS and DFS between the endometriod carcinoma of the IBG3 stage and the nonendometrioid forms of the EC stage I and the difference in the 5-year survival was about 10 % in favor of endometrioid carcinoma. Adjunctive chemotherapy did not improve the long-term outcome of treatment in general, as well as separately in the IBG3 stage of the endometrioid carcinoma stage and the nonendometrioid EC stage I. In the both groups, the difference in the 5-year OS was about 10 % in favor of the subgroups with chemotherapy. Thus, the question of the role of chemotherapy in treatment with high-risk EC is not resolved and requires further research.
本研究致力于研究高危期子宫内膜癌(EC)患者的长期治疗效果和辅助化疗对其生存期的影响,具体取决于组织学肿瘤类型。该研究纳入了2006-2010年在白俄罗斯接受治疗的225例IBG1期子宫内膜癌和非子宫内膜样I期癌症(浆液性、透明细胞癌、未分化癌、癌肉瘤)患者。高危EC的5年总生存率(OS)、肿瘤特异性生存率(CSS)和无病生存率(DFS)分别为66.7±3.2、77.4±2.9和77.0±2.9%,10岁生存率分别为53.7±4.5、69.7±4.2和69.3±4.2%。不同形态肿瘤类型的生存率差异无统计学意义,但IBG3期子宫内膜样癌被定义为高危EC最有利的形式,未分化癌和癌肉瘤是最不利的形式。IBG3期子宫内膜癌与EC期非子宫内膜癌的OS、CSS和DFS差异无统计学意义,子宫内膜癌5年生存率差异约为10%。总的来说,辅助化疗并没有改善治疗的长期结果,在子宫内膜样癌IBG3期和非子宫内膜样EC期也没有改善。在两组中,化疗亚组的5年OS差异约为10%。因此,化疗在高危EC治疗中的作用问题尚未解决,需要进一步研究。
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引用次数: 0
DESIGNING HIGH-PERFORMANCE KNOWLEDGE-BASED MACHINES FOR MANUFACTURE OF POLYMER COMPOSITE PRODUCTS 设计高性能的基于知识的机器制造聚合物复合材料产品
Pub Date : 2018-05-20 DOI: 10.29235/1561-8323-2018-62-2-244-249
M. Ksenofontov
The concept of designing a family of high-performance machines and devices is presented. This family is intended for the implementation of the production technologies of polymer materials with predetermined properties. The materials have been developed as a result of complex physical and chemical studies of the structure and properties of complex organic compounds with the use of modern theoretical and experimental methods. The principal basis of the proposed monomeric-oligomeric technology is concerned with the controlled processes of reactive compound transformation into gas-filled ones by a direct liquid phase transition into a condensed state.
提出了设计一系列高性能机器和器件的概念。该系列旨在实现具有预定性能的聚合物材料的生产技术。这些材料是利用现代理论和实验方法对复杂有机化合物的结构和性质进行复杂的物理和化学研究的结果。所提出的单体-低聚物技术的主要基础是通过直接液相转变为缩合态来控制反应性化合物转化为充满气体的过程。
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引用次数: 0
О ПАРАМЕТРИЗАЦИИ ПРЕОБРАЗОВАНИЙ КОМПЛЕКСНОЙ ГРУППЫ ЛОРЕНЦА ДЛЯ ПРОСТРАНСТВ С ВЕЩЕСТВЕННОЙ МЕТРИКОЙ 关于洛伦茨综合群变换的参数化,用于物理计量空间
Pub Date : 2018-05-20 DOI: 10.29235/1561-8323-2018-62-2-159-163
Ю. А. Курочкин, Л. М. Томильчик
The generalization of the vector parametrization of Lorentz group transformations to the case of the complex Lorentz group SU(3.1) saving the invariant real bilinear form is realized. The composition law and the subgroup structure of the group SU(3.1) are defined.
将洛伦兹群变换的矢量参数化推广到复洛伦兹群SU(3.1)的情形,保留了不变实双线性形式。定义了群SU(3.1)的组成规律和子群结构。
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引用次数: 0
АБСОЛЮТНАЯ УСТОЙЧИВОСТЬ В ЗАДАЧАХ ОПТИМАЛЬНОГО ВЫБОРА С ФИКСИРОВАННЫМ ПРОШЛЫМ 固定过去的最佳选择任务的绝对稳定性
Pub Date : 2018-05-20 DOI: 10.29235/1561-8323-2018-62-2-147-150
M. Y. Kovalyov
A novel approach to solving optimal selection problems under dynamic uncertainty is described. The approach is called absolute robustness with fixed past. An efficient algorithm is presented for the main problem and several its variants. The approach can be employed for solving other combinatorial optimization problems under dynamic uncertainty.
提出了一种求解动态不确定性条件下最优选择问题的新方法。这种方法被称为具有固定过去的绝对稳健性。针对主要问题及其变体,提出了一种有效的算法。该方法可用于求解其他动态不确定组合优化问题。
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引用次数: 2
ON THE TWO-PARTICLE GRAVITATIONAL INTERACTION ENERGY PROBLEM 关于两粒子引力相互作用能问题
Pub Date : 2018-03-05 DOI: 10.29235/1561-8323-2018-62-1-41-50
L. M. Tomilchik
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引用次数: 0
STRUCTURAL DETERMINANTS OF Bax DISPLACMENT FROM THE TOM/Bax COMPLEX BY tBid DURING APOPTOSIS 凋亡过程中由tBid从TOM/Bax复合物中转移Bax的结构决定因素
Pub Date : 2018-03-05 DOI: 10.29235/1561-8323-2018-62-1-73-77
V. Urban, H. V. Dudko, V. Veresov
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引用次数: 0
STRUCTURE OF RAMIFIED DISCRETELY VALUED HENSELIAN DIVISION ALGEBRAS WITH INVOLUTIONS 具有对合的分枝离散值henselian除法代数的结构
Pub Date : 2018-03-05 DOI: 10.29235/1561-8323-2018-62-1-7-12
V. Yanchevskiĭ, A. Ryzhkov
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引用次数: 0
期刊
Doklady Akademii nauk
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