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2009 14th National Biomedical Engineering Meeting最新文献

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Design and implementation of radio frequency glow discharge system 射频辉光放电系统的设计与实现
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130265
Erhan Ocak, H. A. Yucer, I. Kocum, Dilek Cokeliler
Radio frequency glow discharge system is used for processing the fourth state of matter as called plasma in laboratory condition. Plasma state at room temperature is novel technique for biomedical applications especially in modification of sensor and different type of biomaterial surfaces to have proper functionality (improvement of hidrophilicity, hydrophobicity, tissue compability, blood compability etc.). In this study designs the parts of RF plasma system, RF generator, impedance matching and power source which will drive the 150 watt RF power amplifier are presented. This power which is produce by system, is applied on reference surface with the aid of electrodes. In this scope the power, which is get high frequency, is used for generating plasma at allowable value of inert gases and monomers on low pressure (10−3 Torr) and reference biomaterial surface will be modified homogeneously by this plasma generation.
在实验室条件下,射频辉光放电系统用于处理被称为等离子体的物质的第四态。室温等离子体状态是生物医学应用的一项新技术,特别是用于修饰传感器和不同类型的生物材料表面,使其具有适当的功能(改善亲水性、疏水性、组织相容性、血液相容性等)。本文介绍了射频等离子体系统、射频发生器、阻抗匹配和驱动150瓦射频功率放大器的电源部分的设计。这种由系统产生的能量借助电极作用在参考表面上。在此范围内,高频功率用于在惰性气体允许值下产生等离子体,单体在低压(10 - 3 Torr)和参考生物材料表面均匀修饰。
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引用次数: 0
A device for functional and cosmetic treatment of the Lagophthalmos due to facial palsy 一种面瘫致Lagophthalmos的功能及美容治疗装置
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130267
M. Aşık, Burak Guclu
A new device for correction of eyelid problems due to facial palsy was studied. Ineffectiveness of the upper eyelid of the paralyzed side for totally closure is called lagophthalmos which may cause drying and irritation8 rabbits were injected with local anesthetics to induce temporary facial palsy and Lagophthalmos. In order to provide functionality to the upper eyelids, Ferromagnetic pieces were placed on the eyelid of the rabbits. The newly designed device moves the eyelids by alternating the steel pieces. The control group didn't wear the device. The device group results and control group results were compared statistically. All animals observed during the experiment and recorded to video tapes. The data collected from video records were analyzed to test the statistical difference between control and the treated group.
研究了一种用于面瘫眼睑矫正的新装置。麻痹侧的上眼睑不能完全闭合称为lagophthalmos,可能引起干燥和刺激。我们给兔注射局麻药诱导暂时性面瘫和lagophthalmos。为了保证上眼睑的功能,我们在兔的眼睑上放置了铁磁片。这种新设计的装置通过钢片的交替来移动眼睑。对照组不佩戴该装置。器械组结果与对照组结果进行统计学比较。实验过程中对所有动物进行观察并录像。对视频记录收集的数据进行分析,以检验对照组与治疗组之间的统计学差异。
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引用次数: 0
Production of HAP coating on 316L stainless steel substrates by sol-gel technique 溶胶-凝胶法制备316L不锈钢基板HAP涂层
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130326
F. Ak Azem, A. Cakir
In recent years, synthetic hydroxyapatite (HAP) has attracted much interest because of the quest for new generation implants able to promote rapid osteointegration and having longer lifetimes. HAP a major inorganic component of bone, has been increasingly used as a bioceramic coating for load-bearing implants to improve fixation to natural bone tissue. In this study, HAP coating was synthesized using a sol-gel processing on 316L stainless steel substrate and heat treated at different calcination temperatures. The formation of HAP and other compounds were identified and characterized using X-ray diffraction spectroscopy (XRD), Fourier Transform Infrared (FTIR) and Scanning Electron Microscopy (SEM). It was found that crystallinity, structure and morphology of the coatings varied depending on calcination temperature of the layer. The surface morphology of the HAP coating calcined at 500°C displayed porous and crack free structure.
近年来,合成羟基磷灰石(HAP)引起了人们的极大兴趣,因为人们寻求能够促进快速骨整合和具有更长的使用寿命的新一代植入物。羟基磷灰石是骨的主要无机成分,已越来越多地用作生物陶瓷涂层,用于承重植入物,以改善对天然骨组织的固定。本研究采用溶胶-凝胶法在316L不锈钢基体上合成HAP涂层,并在不同的煅烧温度下进行热处理。利用x射线衍射光谱(XRD)、傅里叶变换红外光谱(FTIR)和扫描电子显微镜(SEM)对HAP等化合物的形成进行了鉴定和表征。结果表明,涂层的结晶度、结构和形貌随煅烧温度的变化而变化。500℃煅烧后的HAP涂层表面形貌为多孔无裂纹结构。
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引用次数: 3
Electrically stimulated breast model's thermal imaging simulations 电刺激乳房模型的热成像模拟
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130294
Feza Carlak, N. G. Gencer
Different tissues energy consuming values show differences from each other. Conductivity and metabolic heat source of the tissue alter whether it is healthy or not. The temperature differences of tissues take the thermal infrared imaging into very important and vital point. It was not possible to be able to detect these amounts of differences with the early instrumentation and technology. However, in recent years by the improvement of sensitivity of detectors and cameras it is now possible to sense these amounts of temperature differences. Infrared imaging has a limited performance for the breast cancer diagnosis which occurs especially due to patient moving. Nevertheless, this performance can be improved by applying low frequency currents in medical safety limits. By the help of current application, temperature differences of tissues which have different electrical and thermal properties can be increased and malignant tissue can be distinguished in the obtained thermal image. In this study, woman breast and cancerous tissue are two dimensionally modeled. By using realistic values for regular and cancerous tissue Pennes bio heat equation is solved with finite element method. Simulations are implemented for different tumor locations. Whenever malignant tissue approaches to the skin surface, higher temperature differences are obtained. Imaging performance is increased with current application and tumors can be sensed at 4.5 cm depth with the modern state-of-the-art thermal infrared imagers (possess approximately 10 °mK sensitivity).
不同组织的能量消耗值存在差异。组织的传导性和代谢热源改变了组织是否健康。组织的温差使热红外成像成为非常重要和至关重要的一点。用早期的仪器和技术是不可能检测到这些差异的。然而,近年来,由于探测器和照相机的灵敏度的提高,现在有可能探测到这些数量的温差。红外成像在乳腺癌诊断中的作用有限,尤其是在患者移动的情况下。然而,这种性能可以通过在医疗安全限制下应用低频电流来改善。利用当前的应用,可以增加具有不同电性和热性的组织的温差,并在获得的热图像中区分恶性组织。在这项研究中,女性乳房和癌组织是二维建模的。利用正常组织和癌组织的实际值,用有限元法求解了Pennes生物热方程。对不同的肿瘤位置进行了模拟。当恶性组织接近皮肤表面时,获得更高的温差。成像性能随着目前的应用而提高,使用现代最先进的热红外成像仪(具有大约10°mK的灵敏度)可以在4.5 cm深度检测肿瘤。
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引用次数: 0
Detection of BIS stage levels via fuzzy clustering approach 利用模糊聚类方法检测BIS阶段水平
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130356
Gözde Ulutagay, E. Nasibov
In this study, FCM (Fuzzy c-Means) and FN-DBSCAN (Fuzzy Neighborhood DBSCAN) based algorithms are handled in order to use clustering methods in the determination of the stage values of BIS series data. The FN-DBSCAN algorithm is advantageous in such a way that it integrates the speed of the well-known DBSCAN (Density Based Spatial Clustering of Applications with Noise) and the robustness of the NRFJP (Noise-Robust Fuzzy Joint Points) algorithms. Such a property provides an advantage also in the detection of stable interval epochs. As a result of the computational experiments, we can conclude that FN-DBSCAN-based algorithm gives more realistic results than the FCM-based algorithm to recognize the stable duration intervals and the BIS stages in the measurement series.
本研究采用FCM (Fuzzy c-Means)和FN-DBSCAN (Fuzzy邻域DBSCAN)算法,利用聚类方法确定BIS序列数据的阶段值。FN-DBSCAN算法的优势在于它集成了著名的DBSCAN(基于噪声的应用的密度空间聚类)的速度和NRFJP(噪声-鲁棒模糊连接点)算法的鲁棒性。这种性质也为稳定区间期的探测提供了优势。计算实验结果表明,基于fn - dbscan的算法在识别测量序列中的稳定持续时间间隔和BIS阶段方面比基于fcm的算法更加真实。
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引用次数: 1
Classification of microorganism species using Discriminant Analysis 用判别分析法对微生物种类进行分类
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130303
B. H. Aksebzeci, S. Kara, M. H. Asyali, Yasemin Kahraman, O. Er, E. Kaya, H. Ozbilge
Identification of microorganisms causing root canal infections is an important step in the treatment of these infections. Cultivating the microorganism involved is a relatively difficult and time consuming process. Therefore, clinicians prefer to follow a treatment method based on their prior experience, rather than identifying the related pathogen microorganism and choosing a treatment strategy accordingly. In this study, we have acquired odor data using an electronic-nose equipment with 32 carbon polymer sensors, from pure cultures of 7 microorganisms which are typical causes of root canals infections. We have worked on 28 specimens that are prepared at the Microbiology Laboratory of Pharmacy Faculty. Therefore, there were 4 odor data samples for each of the 7 microorganism types. We have then processed odor data using different pre-processing and dimensions reduction methods and obtained 18 different datasets. We have finally classified these datasets into 7 groups using Discriminant Analysis (DA) and investigated performance of several subtypes of DA algorithm, namely linear, Mahalanobis and quadratic. We have observed that the quadratic approach produces relatively better classification performance. Besides, we have figured out the impact of different pre-processing methods on the classification accuracy.
鉴定引起根管感染的微生物是治疗这些感染的重要步骤。培养所涉及的微生物是一个相对困难和耗时的过程。因此,临床医生更倾向于根据他们之前的经验来遵循一种治疗方法,而不是识别相关的病原体微生物并选择相应的治疗策略。在这项研究中,我们使用带有32个碳聚合物传感器的电子鼻设备,从7种微生物的纯培养物中获得了气味数据,这些微生物是引起根管感染的典型原因。我们对药学院微生物实验室准备的28个标本进行了研究。因此,7种微生物类型各有4个气味数据样本。然后,我们使用不同的预处理和降维方法处理气味数据,得到18个不同的数据集。最后,我们使用判别分析(DA)将这些数据集分为7组,并研究了几种类型的DA算法的性能,即线性、马氏和二次。我们已经观察到二次方法产生了相对更好的分类性能。此外,我们还研究了不同的预处理方法对分类精度的影响。
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引用次数: 0
The biomechanİcal properties of meniscus 半月板的biomechanİcal特性
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130364
H. Hasan, Cecen B. Berivan, B. Lutfu, Erduran D. Mehmet, Karakasli E. Ahmet
In this study, the biomechanical properties of meniscus under pull-out and compression forces are investigated.
在本研究中,研究了半月板在拉出力和压缩力作用下的生物力学特性。
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引用次数: 1
Interactive education system for medicine and engineering using three dimensional virtual environments 基于三维虚拟环境的医学与工程交互教育系统
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130329
Ugras Erdogan, A. Ozkurt, M. Ozgoren, C. Guzelis, Y. Abacioğlu, O. Dicle
Three dimensional modeling and simulation software are becoming more widespread in many fields with the emphasis on engineering, military and medical applications. The main important features of these applications are fast prototyping, simulation of scientific and engineering problems under different conditions and interactive user interface. Therefore, an opportunity for a fast visual education course and understanding the physical and mathematical reasons lying under the problems is presented to engineers, military and scientific researches in the respective fields. The main requirements of these applications are high performance computer systems and user interfaces that feature an easier interaction. The fast developing computer architecture maintains the necessary architecture and enables the applications to improve. Considering above and the expectations of Dokuz Eylül University Faculty of Medicine, the development of a virtual environment software that will model the predefined medical processes with user interaction has been aimed. In this paper, the 1. section is reserved for basic concepts and field applications. The hardware and software infrastructure and algorithm development process we used are presented in the 2. section. The 3. section presents the completed stages and first results of our application. The final section which is the 4. section is reserved for the conclusion and future work.
三维建模和仿真软件在许多领域变得越来越普遍,重点是工程,军事和医疗应用。这些应用程序的主要特点是快速原型,在不同条件下模拟科学和工程问题以及交互式用户界面。因此,为工程师、军事和科学研究人员提供了一个快速视觉教育课程和理解问题背后的物理和数学原因的机会。这些应用程序的主要要求是高性能的计算机系统和更容易交互的用户界面。快速发展的计算机体系结构维护了必要的体系结构,使应用程序得以改进。考虑到以上和Dokuz eyyl大学医学院的期望,开发一个虚拟环境软件,将与用户交互对预定义的医疗过程进行建模。在本文中,1。部分保留基本概念和现场应用。本文介绍了所使用的硬件和软件基础结构以及算法开发过程。部分。的3。节介绍了我们的应用程序的完成阶段和初步结果。最后一个部分是4。章节为结束语和后续工作保留。
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引用次数: 3
Diagnosis of Prostat Cancer using Artificial Neural Networks 应用人工神经网络诊断前列腺癌
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130296
M. Sinecen, Murat Çinar, Omer Karal, M. Engin, Y. Z. Atesçi, Metehan Makinaci, B. Cakmak
Prostat cancer is a disease which is the most common and which is also the second deadly in men. When prostat cancer can be diagnosed early, medical surgery operation can be performed and the disease can be treated.
前列腺癌是一种最常见的疾病,也是男性第二致命的疾病。当前列腺癌可以早期诊断时,可以进行外科手术治疗。
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引用次数: 0
Shockwave simulation in electrohydrolic lithotripsy and wave performance optimization 电液碎石中的冲击波模拟及冲击波性能优化
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130284
E. Çiftçi, B. Yilmaz
Lithotripsy systems are commonly used to break kidney stones into fragments. Nowadays these systems are also used in orthopedic operations. There are several ongoing investigational studies on lithotripsy systems in the treatment of cancer and cardiovascular diseases. Because of these new application areas we need novel lithotripter designs for different kinds of treatment strategies. The best way to reduce design time and cost is to create a computational model of the lithotripsy system. In this study the finite difference time domain (FDTD) method were used while constructing the computational model of the lithotripsy system. While implementing the model, most of the physical system parameters were defined as an input and/or as a variable in the simulations. We tested several realistic parameters used in the simulations and compared the results with the expected outcomes and optimized our system accordingly. Finally, we studied the effects of changing the input parameters like ellipsoide reflector size, and focus point misalignment. In conclusion, to reduce design costs in various medical applications that use shockwave principle this computer-based simulation platform may be suitable.
碎石系统通常用于将肾结石破碎成碎片。如今,这些系统也用于骨科手术。有几个正在进行的碎石系统治疗癌症和心血管疾病的调查研究。由于这些新的应用领域,我们需要新的碎石机来设计不同的处理策略。减少设计时间和成本的最佳方法是建立碎石系统的计算模型。本文采用时域有限差分法(FDTD)建立了碎石系统的计算模型。在实现模型时,大多数物理系统参数被定义为模拟中的输入和/或变量。我们测试了模拟中使用的几个实际参数,并将结果与预期结果进行了比较,并对系统进行了相应的优化。最后,研究了椭球面反射镜尺寸、焦点不对准等输入参数的变化对系统的影响。综上所述,为了降低各种医疗应用中使用冲击波原理的设计成本,基于计算机的仿真平台可能是合适的。
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引用次数: 0
期刊
2009 14th National Biomedical Engineering Meeting
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