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2009 14th National Biomedical Engineering Meeting最新文献

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Coarray sampling methods for forward looking IVUS imaging 前瞻性IVUS成像的阵列采样方法
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130318
C. Tekes, M. Karaman
Forward looking intravascular ultrasound (IVUS) imaging with ring arrays can produce real time volumetric imaging. Due to the limited catheter size, data acquisition and image reconstruction are based on synthetic phased array processing to reduce the motion artifacts. The number of signal firing/receivening steps must be kept small. This can be achieved by reducing the redundant spatial frequency components. For this purpose, we explore different sampling methods. We tested the imaging performance of coarrays with different sampling schemes on the simulated point spred functions of original and control coarray sets. Simulation results show equivalent performance in 40 dB for an annular ring array of 64 elements with 2049 original and 350 reduced sets.
前视血管内超声(IVUS)成像与环阵列可以产生实时的体积成像。由于导管尺寸有限,数据采集和图像重建基于合成相控阵处理,以减少运动伪影。信号发射/接收步骤的数量必须保持小。这可以通过减少冗余的空间频率分量来实现。为此,我们探索了不同的抽样方法。对不同采样方案的同轴阵列的成像性能进行了测试,分别对原始同轴阵列和控制同轴阵列的模拟点扩散函数进行了测试。仿真结果表明,64元环形阵列具有2049个原始集和350个简化集,在40 dB下具有等效性能。
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引用次数: 0
Multi-channel acoustic mapping of respiratory system based on adventitious sound source separation 基于非定声源分离的呼吸系统多通道声学映射
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130366
I. Sen, M. Saraçlar, Y. Kahya
The aim of this study is to localize the pathological compartments of the lung based on the characteristics of the modified pulmonary sounds. Sound signals recorded simultaneously at more than one point on the posterior chest wall are subjected to source separation methods in order to separate sound components associated with the disease. For this study, Basic Independent Component Analysis (BICA), Separation By Autocovariances (SBA) and Convolutive Blind Source Separation (CBSS), out of various source separation methods, are adopted and used. The measure proposed to find the most similar among the extracted independent components to the true source is kurtosis and Kullback-Liebler (K-L) distance. After the similarities between measured signals and the chosen component are located as coefficients onto the recording points on the chest wall and thereby formed matrix is visually improved via interpolation, a two-dimensional map is obtained, although with low resolution, showing estimated pathology source location and audibility distribution of the adventitious sound component around this source. This study is intended to be a pioneer to studies on acoustic-based respiratory system imaging which can function as an alternative to computer chest tomography in some necessary circumstances, and complementary in others.
本研究的目的是根据改变的肺音的特征来定位肺的病理腔室。在后胸壁上多个点同时记录的声音信号采用源分离方法,以便分离与疾病相关的声音成分。本研究采用了多种源分离方法中的基本独立分量分析(Basic Independent Component Analysis, BICA)、自协方差分离(Separation By Autocovariances, SBA)和卷积盲源分离(Convolutive Blind Source Separation, CBSS)。在提取的独立分量中寻找与真实源最相似的度量是峰度和Kullback-Liebler (K-L)距离。将测量信号与所选分量之间的相似度作为系数定位到胸壁上的记录点上,并通过插值直观地改进形成的矩阵,得到二维图,尽管分辨率较低,但显示了估计的病理源位置和该源周围的非定音分量的可听性分布。本研究旨在成为基于声学的呼吸系统成像研究的先驱,在某些必要的情况下可以作为计算机胸部断层扫描的替代方法,在其他情况下可以作为补充。
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引用次数: 0
Evaluation of anxiety related changes in skin conductance and blood volume pulse signals during coronary angiography 冠状动脉造影时皮肤电导和血容量脉搏信号焦虑相关变化的评价
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130285
S. Okkesim, M. H. Asyali, S. Kara, M. Kaya, İdris Ardiç
Although, stress, sleep deprivation, excessive fatigue and inattention are common health problem in advanced society, there are many methodological problems that make it difficult to measure these emotional states in clinical situations. The main goal of this study is to investigate whether variation of stress due to treatment techniques used in a hospital setting can be successfully assessed and/or quantized using physiological variables. To this end, blood volume pulse and skin conductance signals of 8 patients who underwent angiography operation at the Cardiology Center of Erciyes University (Kayseri, Turkey), are obtained. Recordings were done at three stages: one hour before, during, and one hour after the angiography test. Our preliminary results indicate that the changes in the physiological variables across different subjects are remarkably consistent. This promising result is motivating us to consider and include other possible physiological variables and/or signals in our recording scheme to quantitatively assess changes in the emotional state of subjects undergoing critical operations.
虽然压力、睡眠不足、过度疲劳和注意力不集中是发达社会中常见的健康问题,但有许多方法上的问题使得在临床情况下难以测量这些情绪状态。本研究的主要目的是调查医院环境中使用的治疗技术引起的压力变化是否可以使用生理变量成功评估和/或量化。为此,我们获得了在土耳其埃尔西耶斯大学(Erciyes University, Kayseri, Turkey)心脏病学中心接受血管造影手术的8例患者的血容量、脉搏和皮肤电导信号。记录分为三个阶段:造影前一小时、造影中一小时和造影后一小时。我们的初步结果表明,不同受试者的生理变量的变化是非常一致的。这一有希望的结果促使我们考虑并将其他可能的生理变量和/或信号纳入我们的记录方案中,以定量评估受试者在进行关键手术时情绪状态的变化。
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引用次数: 2
Fiber tracking using recursive stack data structure 光纤跟踪采用递归堆栈数据结构
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130350
D. G. Duru, M. Ozkan
In diffusion tensor magnetic resonance imaging (DT-MRI), each voxel is assigned a tensor that describes local water diffusion. In this study, the eigenvectors of the diffusion tensor are analyzed based on stack linked list application. The aim of the study is to develop a reliable and rapid tractography algorithm. The analyzed image sample consists of 60 diffusion weighted human brain images and a null image namely the T2 image creating a set of intensity images of size 256×256×60×30. The eigenvectors of D is calculated in every pixel, apparent diffusion coefficient ADC is represented with respect to D. The idea of the proposed method is to accomplish the fiber pathway by starting from a single, selected node taking every node in other words all the information of the eigenvector of the whole brain into account. Via the proposed study, an elimination method for the main drawback in DTI literature namely the uncertainty regions are aimed.
在扩散张量磁共振成像(DT-MRI)中,每个体素被分配一个描述局部水扩散的张量。本文基于栈链表的应用,分析了扩散张量的特征向量。本研究的目的是开发一种可靠、快速的神经束成像算法。所分析的图像样本由60张扩散加权的人脑图像和一张空图像即T2图像组成,形成一组大小为256×256×60×30的强度图像。在每个像素中计算D的特征向量,表观扩散系数ADC相对于D表示。所提出的方法的思想是从单个选定的节点开始,考虑到整个大脑特征向量的所有信息,从而完成光纤通路。通过提出的研究,针对DTI文献中的主要缺陷即不确定区域,提出了一种消除方法。
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引用次数: 0
Serbest dalgiclarda iYKAS ile serebrovaskuler reaktivite olcumu
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130332
Deniz Nevsehirli, Ata Akin
Effect of consecutive maximal dry breath-holds was compared between two groups of free divers with different experience levels and a control group. Hemoglobin concentration ([Hb], by functional near infrared spectroscopy, fNIRS), heart rate and systemic oxygen saturation (SO2, by pulse oxymetry) measurements were performed during four consecutive maximal dry breath-holdsChange in [Hb] (Δ[Hb]), change in SO2 (ΔSO2) and breath-hold indices (BHI_Δ[Hb], BHI_ΔSO2) normalized to hold durations calculated for each breath-hold. Analyses over these indices showed statistical difference between groups (p≪5×10−5 for both indices). Free diver groups exhibited a higher slope of increase of the indices among consecutive breath holds compared to the control group elucidating an enhanced reactivity to hypoxia. Our results indicate that cerebrovascular reactivity to hypercapnia can be learned and trained and the level of reactivity can be reliably quantified by fNIRS.
比较了两组不同经验水平的自由潜水员和对照组连续最大干式屏气的效果。血红蛋白浓度([Hb],通过功能性近红外光谱,fNIRS),心率和全身氧饱和度(SO2,通过脉搏血氧仪)测量在连续四次最大的干屏气期间进行[Hb]变化(Δ[Hb]), SO2变化(ΔSO2)和屏气指数(BHI_Δ[Hb], BHI_ΔSO2)归一化,以计算每次屏气的持续时间。对这些指数的分析显示各组之间存在统计学差异(两个指数p≪5×10−5)。与对照组相比,自由潜水组在连续屏气中表现出更高的指数增长斜率,说明对缺氧的反应性增强。我们的研究结果表明,脑血管对高碳酸血症的反应性是可以学习和训练的,反应性水平可以通过近红外光谱可靠地量化。
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引用次数: 0
Image processing method for artificial sight systems based on contrast information 基于对比度信息的人工视觉系统图像处理方法
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130320
M. Ozden, Nergis Karadoruk, I. Karagoz
In this study, an image processing algorithm is developed for epiretinal implants. In this algorithm, it is presented an approach for adaptive frequency control that is one of the important parameters to generate stimuli. Standard 240×320 pixels video images in RGB format are processed as 10×10 pixel blocks. Consequently, it is designed to activate 24×32 pixels electrode matrix. As a retinal filter Gabor filter is preferred to DoG filter that is usually used in literature. The changes in pixels are modeled by using temporal filter. The results that belong to study and forward opinions are also presented.
本研究开发了一种视网膜外植入物的图像处理算法。在该算法中,提出了一种自适应频率控制方法,频率是产生刺激的重要参数之一。RGB格式的标准240×320像素视频图像被处理为10×10像素块。因此,它被设计为激活24×32像素电极矩阵。作为一种视网膜滤光器,Gabor滤光器优于文献中常用的DoG滤光器。利用时间滤波器对像素的变化进行建模。并给出了研究结果和前瞻意见。
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引用次数: 0
A Monte Carlo Simulation for photon migration in non-homogeneous medium 非均匀介质中光子迁移的蒙特卡罗模拟
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130301
R. U. Tok, Tamer Olmez, A. Akın
In this study, we developed a Monte Carlo Simulation for forward problem of photon migration in non-homogeneous medium. We validated our program against tMCimg, developed by Boas and colleagues, for some simple geometries. Eventually our program gives reasonable results for mediums which are not too complex but for more complex mediums because of very long computational time, it's not practical although theoretically there is no problem.
在这项研究中,我们建立了一个蒙特卡罗模拟非均匀介质中光子迁移的正演问题。我们用Boas及其同事开发的tMCimg对一些简单的几何图形验证了我们的程序。最终,我们的程序对不太复杂的介质给出了合理的结果,但对于更复杂的介质,由于计算时间很长,虽然理论上没有问题,但这并不实际。
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引用次数: 0
Extendable intramedullary nail with mechanical loading 带机械载荷的可伸缩髓内钉
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130323
B. Uzun, O. Baran, H. Havitcioglu
There are various extremity lengthening methods in the literature. Lentghening with intramedullary nails is also important method which is emphasized recent years. In this study, in the light of previous studies, it is aimed to develop a new expandable intramedullary system providing lengthening in order to remove previous problems and complications and to annihilate leg length discrepancies at present and future without second surgical intervention as far as possibble by lenghtening the intramedullary nail.
文献中有各种各样的四肢延长方法。髓内钉延长也是近年来受到重视的一种重要方法。在本研究中,根据以往的研究,旨在开发一种新的可扩展的髓内钉系统,通过延长髓内钉来延长,以消除以前的问题和并发症,并尽可能消除目前和将来不需要第二次手术干预的腿长差异。
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引用次数: 0
Tissue welding by Thulium laser system: Predosimetry studies 铥激光系统组织焊接:预剂量学研究
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130347
A. Sennaroğlu, M. Gulsoy, H. Kalaycıoğlu, N. Topaloglu, A. Kurt, A. Sennaroğlu, M. Gulsoy
Laser tissue welding predosimetry studies are performed on Wistar rat skin by using diode-pumped and fiber-coupled Thulium (Tm:YAP) laser system emitting at 1980-nm, which is developed for medical applications. The success of laser tissue welding at 100 mW ve 160 mW of Tm:YAP laser powers is analyzed by macroscopy and histology results. Tm:YAP laser dosimetry of 100 mW, 5 second (34,66 W/cm2) is found successful for tissue welding studies.
采用专为医疗应用而开发的1980-nm激光泵浦和光纤耦合铥(Tm:YAP)激光系统,在Wistar大鼠皮肤上进行激光组织焊接预剂量测定研究。通过显微观察和组织学结果分析了在100 mW和160 mW Tm:YAP激光功率下激光组织焊接的成功。Tm:YAP激光剂量测定100 mW, 5秒(34,66 W/cm2)被发现成功用于组织焊接研究。
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引用次数: 0
Immobilization of thrombin to bio/chemically modified synthetic fabrics 凝血酶在生物/化学改性合成织物上的固定化
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130346
Alper Akkaya, N. Pazarlıoğlu
Processed synthetic polymers used in medical textile are used directly or functionalized by immobilization of bioactive molecules. Textile products made by synthetic polymers are durable, resistant to chemical reactions and have inert structures. Textile products made by synthetic polymers usually have not functional groups for immobilization. So modification could be done for formation of functional groups. Immobilization of bioactive molecules could be done by functional groups. In this study, thrombin was immobilized to textile products made by synthetic polymers. So Textile products made by synthetic polymers was added a new character which was blood stopper. The product was reliable because of source.
医用纺织品中使用的加工合成聚合物可直接使用或通过固定化生物活性分子实现功能化。由合成聚合物制成的纺织品经久耐用,耐化学反应,具有惰性结构。由合成聚合物制成的纺织品通常没有用于固定的官能团。所以可以通过修饰来形成官能团。生物活性分子的固定化可以通过官能团来完成。本研究将凝血酶固定在由合成聚合物制成的纺织品上。因此,用合成聚合物制成的纺织品增加了一个新特性,即血液阻滞剂。这个产品是可靠的,因为来源可靠。
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引用次数: 0
期刊
2009 14th National Biomedical Engineering Meeting
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