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2009 14th National Biomedical Engineering Meeting最新文献

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Investigation of different modalities of laser delivery for skin welding 蒙皮焊接中不同激光输送方式的研究
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130321
O. Tabakoglu, N. Topaloglu, M. Gulsoy
980-nm laser skin welding studies have been performed since 2005 by our group and promising results were obtained. As a continuation of that study, in this current research, it was aimed to compare 2 different application methods by histological and mechanical tests. 1-cm long, 6 incisions were welded with 980-nm diode laser by two different applications: high power (6W-400ms) and low power (0.5W–5s). Throughout 21-day healing period, incision were removed from dorsal skin of Wistar rats under anesthesia on control days (1st, 4th, 7th, 14th and 21st) for histology and mechanical tests. Closure index, thermally altered areas, epidermal thickness and granulation areas of H&E stained samples were calculated. Breaking point of incisions during mechanical tensile test that has 5 mm / min crosshead speed was noted. In this study, effects of high (6W–400ms) and low power (0.5W–5s) applications of same energy level (2.5J) 980-nm diode laser irradiation on skin tissue was shown.
本课程组自2005年开始进行980纳米激光蒙皮焊接的研究,取得了可喜的成果。作为该研究的延续,本研究旨在通过组织学和力学试验比较两种不同的应用方法。采用高功率(6W-400ms)和低功率(0.5W-5s)两种不同的应用程序焊接980 nm二极管激光器,长1 cm, 6个切口。在21天的愈合期内,于对照组(第1、4、7、14、21天)麻醉下从Wistar大鼠背部皮肤上切除切口,进行组织学和力学试验。计算H&E染色样品的闭合指数、热改变面积、表皮厚度和肉芽面积。在机械拉伸试验中,记录了5毫米/分钟十字速度下切口的断裂点。本研究展示了相同能级(2.5J) 980 nm二极管激光高功率(6W-400ms)和低功率(0.5W-5s)照射对皮肤组织的影响。
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引用次数: 0
Anisotropic conductivity imaging with MREIT using J-substitution algorithm 采用j -替代算法的MREIT各向异性电导率成像
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130292
E. Değirmenci, M. Eyuboglu
Current is applied to the object to be imaged and trajectory of this current inside the object is determined with the help of Magnetic Resonance Imaging (MRI) techniques. Reconstruction of conductivity distribution using this information is called Magnetic Resonance - Electrical Impedance Tomography (MREIT) technique in literature. In this study, a novel anisotropic conductivity reconstruction algorithm for MREIT is proposed. The technique is evaluated on simulated data and obtained results are given.
在磁共振成像技术的帮助下,将电流施加到要成像的物体上,并确定该电流在物体内部的轨迹。利用这些信息重建电导率分布在文献中被称为磁共振-电阻抗断层扫描(MREIT)技术。本文提出了一种新的MREIT各向异性电导率重建算法。用仿真数据对该技术进行了验证,并给出了验证结果。
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引用次数: 0
Automatic registration of follow-up brain MRI scans 自动登记后续脑部核磁共振扫描
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130380
A. Demir, Gozde Unal, K. Karaman
Registration of multiple medical images is required for analysis of both pathological and normal anatomical human body structures. In this study, we defined and automatically detected some anatomical landmarks which are considered to be unaffected from brain deformation such as symmetry axis of brain, nose tips, eye ball centers, and location of center of masses of certain slices. Registration is performed using the physical coordinates of automatically detected landmarks. Registration mapping is assumed to be an affine mapping and transformation matrix is formed using a least squares solution. Registered image is obtained using the estimated transformation matrix and trilinear interpolation. Algorithm performance is demonstrated on both MR image volumes deformed synthetically with a known transformation matrix for validation and baseline and follow-up MRI volumes with unknown transformations.
在对人体病理和正常解剖结构进行分析时,需要对多幅医学图像进行配准。在这项研究中,我们定义并自动检测了一些被认为不受大脑变形影响的解剖标志,如大脑的对称轴、鼻尖、眼球中心和某些切片的质心位置。使用自动检测到的地标的物理坐标进行配准。假设配准映射为仿射映射,利用最小二乘解形成变换矩阵。利用估计的变换矩阵和三线性插值得到配准图像。算法的性能在用已知的转换矩阵进行验证的合成变形的MR图像体积和基线和后续的未知转换的MRI体积上得到了证明。
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引用次数: 3
Analysis of respiration, oxygen saturation and acoustic signals of snoring patients 鼾症患者呼吸、血氧饱和度及声信号分析
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130277
D. D. Demirgunes, O. Eroğul, T. Akcam, Z. Telatar
Snore is a problem, which can be seen in many people and has consequences from distrupting the individual's harmony with environment up to divorce as a familial problem. Snoring patients are analysed in two groups as Simple Snorers and Snorers with Obstructive Sleep Apnea Syndrom (OSAS). Obstructive sleep apnea syndrome (OSAS) is a disease causing serious problems in patients by cessation of upper airway during the sleep. Diagnosis of OSAS is based on the analysis of data recorded from patients in the sleep laboratory during one night by using polisomnograph systems which are defined as gold standard for this subject. Although, snoring is the most definite and early syndrome of OSAS, it might not be sufficient for a clinical diagnosis. In this study, the analysis of respiration (nasal flow), oxigene saturation and acquistic signals that are collected via Biopac Data Acquistition System is performed to distinguish Simple Snorers and Snorers with OSAS. Developed system is considered as a decision support system for physicians by distinguishing which of the patients having the snoring problem require to be taken polisomnograph records in sleep laboratory.
打鼾是一个问题,在很多人身上都可以看到,它的后果从破坏个人与环境的和谐到离婚,都是一个家庭问题。将打鼾患者分为单纯打鼾者和阻塞性睡眠呼吸暂停综合征(OSAS)两组。阻塞性睡眠呼吸暂停综合征(OSAS)是一种在患者睡眠过程中因上呼吸道停止而引起严重问题的疾病。OSAS的诊断是基于对睡眠实验室中患者在一个晚上记录的数据进行分析,并使用被定义为该主题的金标准的polisomography系统。虽然打鼾是OSAS最明确的早期症状,但它可能不足以作为临床诊断。在本研究中,通过Biopac数据采集系统收集的呼吸(鼻流量)、氧饱和度和通气信号进行分析,以区分单纯打鼾者和osa打鼾者。开发的系统可作为医生的决策支持系统,用于识别哪些患者有打鼾问题,需要在睡眠实验室进行睡眠睡眠记录。
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引用次数: 0
Contactless electrical conductivity imaging simulations using FDFD method 用FDFD方法模拟非接触式电导率成像
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130360
C. B. Top, N. G. Gencer
A 3-D Frequency Domain Finite Differences (FDFD) code is developed for electromagnetic simulations of low frequency contactless electrical conductivity imaging. Simulations on discrimination of malign breast tumor are conducted. Required sensitivity of the differential coil system - for detecting a volume of 216mm3 tumor which is located at 1 cm under the skin- are investigated for different frequencies
开发了一种用于低频非接触电导率成像电磁仿真的三维频域有限差分(FDFD)程序。对乳腺恶性肿瘤的判别进行了仿真。差分线圈系统所需的灵敏度——用于检测位于皮肤下1厘米的216mm3体积的肿瘤——在不同的频率下进行了研究
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引用次数: 0
Diagnosis of congestive heart failure patients using Poincare measures derived from ECG signals 心电图信号庞加莱测量诊断充血性心力衰竭
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130287
Y. Isler, M. Kuntalp
In this study, it is investigated whether Poincare map measures can be used in discriminating the patients with congestive heart failure (CHF) from normal subjects and determining the type of CHF as diastolic and systolic. Poincare map measures are calculated from ECG data that is freely available over the Internet for CHF patients and normal subjects and statistically compared using Student-t test. Similar measures are also calculated from ECG data obtained from clinics for discriminating diastolic and systolic CHF patients and statistically compared. As a result, Poincare map measures of SD1, SD2, and SD1/SD2 are found to be statistically significant to discriminate patients with CHF from normals whereas only the SD1/SD2 measure is found to be statistically significant for discriminating diastolic CHF patients from systolic ones.
本研究探讨庞加莱图测量是否可以用于区分充血性心力衰竭(CHF)患者和正常人,并确定CHF的类型为舒张期和收缩期。庞加莱图测量是根据互联网上免费提供的CHF患者和正常受试者的心电图数据计算的,并使用Student-t检验进行统计比较。从临床获得的心电图数据也计算出类似的措施来区分舒张期和收缩期CHF患者,并进行统计学比较。结果发现,庞加莱图测量SD1、SD2和SD1/SD2对于区分舒张期和收缩期CHF患者具有统计学意义,而只有SD1/SD2对于区分舒张期和收缩期CHF患者具有统计学意义。
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引用次数: 4
Femoral artery's Blood Volume Pulse signal modelling 股动脉血容量脉搏信号建模
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130338
Serdar Yilmaz, O. Toker, N. Arslan
Cardiovascular diseases are important disease to affecting our world recently. Numerical and experimental simulations are rapidly increasing in this research area. Blood Volume Pulse uses frequently to diagnose and treatment of this kind of disease. Data was obtained from modeling of blood vessel and blood flow in vitro experimental system, supports for instruct to direction diagnose and treatment of disease. Because of that femoral artery blood volume signal modeling was chosen as goal, has important place in cardiovascular area. Suitable for this purpose centrifugal pump, pump driver card, data acquisition card, flow meter and other equipments were established for close loop control mechanism in our university's laboratory. Results of obtained indicate that is available model of the femoral artery blood flow taken data from the real patients. There is the motivation result to improve new approach diagnosed and treatment ways of different blood vein and blood volume pulse signals modeling.
心血管疾病是近年来影响我们世界的重要疾病。在这一研究领域,数值模拟和实验模拟正在迅速增加。血容量脉冲常用于诊断和治疗这类疾病。数据来源于体外血管和血流实验系统的建模,为指导疾病的诊断和治疗提供支持。因此,以股动脉血容量信号建模为目标,在心血管领域具有重要的地位。为此,在我校实验室建立了离心泵、泵驱动卡、数据采集卡、流量计等闭环控制机构设备。所得结果表明,该模型取材于实际患者的血流量。研究结果对改进不同静脉血容量脉搏信号建模的新方法诊断和治疗方法具有激励作用。
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引用次数: 0
Doppler ultrasound signal denoising based on Grey relational analysis technique 基于灰色关联分析技术的多普勒超声信号去噪
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130309
E. Uzunhisarcikli, F. Latifoğlu, T. Koza, M. Kaya
In this study, Grey relational analysis technique proposed by J.L. Deng has been applied to spectrogram images of clinical mitral valve Doppler signals. A threshold level has been determined to plot maximum frequency envelope from denoised sonogram image using this technique. It is seen that, signal to noise ratio has been improved through Grey relational analysis technique. A software has been realized to support Doppler ultrasound device to diagnose vascular disease. This system has many advanteges that are reducing the computation time, ergonomic, cheapness.
在本研究中,将邓J.L.提出的灰色关联分析技术应用于临床二尖瓣多普勒信号的频谱图图像。确定了一个阈值水平,利用该技术从去噪的超声图像中绘制最大频率包络线。可以看出,通过灰色关联分析技术提高了信噪比。实现了一个支持多普勒超声诊断血管疾病的软件。该系统具有减少计算时间、符合人体工程学、价格低廉等优点。
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引用次数: 1
Synthesis of Nanosized Calcium Deficient Hydroxyapatite by Microwave 微波法制备纳米缺钙羟基磷灰石
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130361
M. Ipekoğlu, S. Altıntaş
In this study, nanosized calcium deficient hydroxyapatite (KEHA) was synthesized using microwave irradiation. The synthesized powder was compared with a sample synthesized without using microwave with respect to the observed phases, particle size and powder morphology based on the XRD, particle size analysis and SEM observations. Studies showed that application of microwave has positive effects on the crystallization of the produced powders.
本研究采用微波辐照法制备了纳米缺钙羟基磷灰石(KEHA)。通过XRD、粒度分析和SEM观察,将合成的粉末与未使用微波合成的样品在物相、粒度和粉末形貌等方面进行了比较。研究表明,微波的应用对粉末的结晶有积极的影响。
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引用次数: 0
Investigation of the effect of playing video games on visual attention and brain hemodynamics with functional near infrared spectroscopy 用功能近红外光谱研究玩电子游戏对视觉注意力和脑血流动力学的影响
Pub Date : 2009-05-20 DOI: 10.1109/LEOS.2009.5343270
S. B. Erdoğan, Canan Bilgin, Beyza Turan, A. Akın
Video game playing is an attractive form of entertainment among school-age children. Although this activity has many adverse effects on child development, there have been only a few studies examining the biological effects of video games on brain activity. The aims of this study were i) to investigate effects of video game playing on attentional capacity and visual skills ii) to relate training induced alterations in performance with regional cerebral oxygenation levels obtained by functional near infrared spectroscopy (fNIRS). 24 high school students (12 video game players and 12 non-video game players) participated in the study. Subjects were asked to perform a task-switching experiment. Cerebral oxygenation level in the prefrontal cortex was measured with a near infrared spectroscopy device. Video game players had shorter reaction times (p≪0.02) to presented stimuli and lower error rates (p≪0.04) when compared to non-video game players. As the task became more difficult; they were able to sustain better performance with more profound increase in prefrontal oxyenation (p≪0.008). The results imply that video game playing alters visual skills and hand-eye coordination. Higher prefrontal oxygenation observed in video game players suggests that limited vascular resources in their brain might be transferred towards areas involved in executive function.
电子游戏对学龄儿童来说是一种很有吸引力的娱乐方式。尽管这种活动对儿童发育有许多不利影响,但只有少数研究调查了电子游戏对大脑活动的生物学影响。本研究的目的是:(1)调查视频游戏对注意力和视觉技能的影响;(2)通过功能性近红外光谱(fNIRS)研究训练引起的表现改变与区域脑氧合水平的关系。24名高中生(12名电子游戏玩家和12名非电子游戏玩家)参与了这项研究。研究对象被要求进行任务转换实验。用近红外光谱仪测量前额叶皮层脑氧合水平。与非电子游戏玩家相比,电子游戏玩家对刺激的反应时间(p≪0.02)较短,错误率(p≪0.04)较低。随着任务变得越来越困难;它们能够通过更大幅度地增加前额叶氧合来保持更好的性能(p≪0.008)。结果表明,玩电子游戏会改变视觉技能和手眼协调能力。在电子游戏玩家中观察到的更高的前额叶氧合表明,他们大脑中有限的血管资源可能被转移到与执行功能有关的区域。
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引用次数: 0
期刊
2009 14th National Biomedical Engineering Meeting
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