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2009 14th National Biomedical Engineering Meeting最新文献

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Investigation of Muscle Fatigue by Processing EMG Signal 肌电信号处理对肌肉疲劳的研究
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130354
Ozlem Cakir, M. Engin, E. Z. Engin, Ufuk Yumrukaya
Surface EMG signals are taken from the human muscle and have some advantages over the needle electrode originated EMG's recordings. In this study, we have processed surface EMG's coming from the normal subject set (7 female and 7 male) to investigate the effects of the muscle fatigue on the 50% maximum voluntary contraction condition. We have observed great correlation between three features which are the slope of the changes of median frequency, number of zero crossing, and wavelet transform based entropy. We also found that the wavelet transform based entropy values have the great abrupt changes for some subjects.
表面肌电信号取自人体肌肉,与针电极产生的肌电信号相比,表面肌电信号具有一些优势。在这项研究中,我们处理了来自正常受试者组(7名女性和7名男性)的表面肌电信号,以研究肌肉疲劳对50%最大自愿收缩条件的影响。我们观察到中位数频率变化的斜率、过零次数和基于小波变换的熵之间有很大的相关性。我们还发现基于小波变换的熵值对某些对象有较大的突变。
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引用次数: 1
Analysis of Magnetic Resonance signal in inhomogenous main magnetic field 非均匀主磁场中磁共振信号的分析
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130278
V. Arpinar, B. M. Eyuboglu
Nuclear Magnetic Resonance (NMR) systems with inhomogenous main magnetic fields, which are used to analyze material properties, have been developed before. Therefore, Magnetic Resonance Imaging (MRI) systems with inhomogenous main magnetic fields can be possibly developed to image tissues. To investigate the possibility of MRI in inhomogenous main magnetic field, Magnetic Resonance (MR) signal has to be analyzed. In this study, MR signal's parameters deviation due to inhomogeneity level change in the main magnetic field of a MRI system is investigated. Analyzed MR signal parameters are signal peak, energy and relaxation constant. Deviations of these parameters, because of inhomogeneity level change in the main magnetic field, are related to change in MRI system's properties. Thus, starting from the MRI system's properties, tolerable inhomogeneity level in main magnetic field can be found.
具有非均匀主磁场的核磁共振(NMR)系统已被用于分析材料的性质。因此,具有非均匀主磁场的磁共振成像(MRI)系统有可能用于组织成像。为了研究在非均匀主磁场中进行核磁共振成像的可能性,必须对核磁共振信号进行分析。本文研究了核磁共振系统主磁场不均匀性电平变化引起的核磁共振信号参数偏差。分析了磁共振信号的参数为信号峰值、能量和松弛常数。由于主磁场的非均匀性水平变化,这些参数的偏差与MRI系统性能的变化有关。因此,从MRI系统的性质出发,可以找到主磁场可容忍的不均匀程度。
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引用次数: 1
Comparison of atlas based segmentation and manual segmentation of hippocampus 基于图谱的海马分割与手工分割的比较
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130369
Hakan Kutucu, Ç. Eker, O. Kitis, A. Gonul
High-resolution Magnetic resonance imaging (MRI) is helpful in diagnosing diseases such as schizophrenia, alzheimer, dementia etc. Brain segmentation is an important preprocess in medical imaging applications. In this study we compare atlas based segmentation and manual segmentation of hippocampus for volumetric measures. A statistically difference was obtained between automatic and manual measurement. We conclude that contemporary techniques are not adequate to obtain sensitive data in some barin structures such as hippocampus core.
高分辨率磁共振成像(MRI)有助于诊断精神分裂症、阿尔茨海默病、痴呆症等疾病。脑分割是医学成像中重要的预处理技术。在这项研究中,我们比较了基于图谱的分割和手工分割海马的体积测量。自动测量和人工测量之间有统计学差异。我们得出的结论是,当代技术不足以获得某些barin结构(如海马核)的敏感数据。
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引用次数: 1
Comparison of 980-nm and 1070-nm in endovenous laser treatment 980 nm与1070 nm在静脉内激光治疗中的比较
Pub Date : 2009-05-20 DOI: 10.1117/12.831906
N. Topaloglu, O. Tabakoglu, M. Ergenoglu, M. Gulsoy
The use of endovenous laser treatment for varicose veins has been increasing in recent years. It is a safer technique than surgical vein stripping. Its complications (e.g. bruising, pain) are less than the complications of surgical vein stripping. But best parameters such as optimum wavelength, power, and application duration are still under investigation to clarify uncertainties about this technique. To prevent its complications and improve its clinical outcomes, the exact mechanism of it has to be known. The aim of this study is to investigate the effect of different laser wavelengths on endovenous laser therapy. In this study 980-nm diode laser and 1070-nm fiber laser were used. Human veins were irradiated with 980-nm and 1070-nm lasers at 8 W and 10 W to find the optimal power and wavelength. After laser application, remarkable shrinkage was observed. Inner and outer diameters of the veins also narrowed for both of the laser types. 10 W of 980-nm laser application led to better shrinkage results.
近年来,静脉内激光治疗静脉曲张的应用越来越多。这是一种比手术静脉剥离更安全的技术。其并发症(如瘀伤、疼痛)比手术静脉剥离的并发症要少。但最佳参数如最佳波长、功率和应用时间仍在研究中,以澄清该技术的不确定性。为了预防其并发症和改善其临床疗效,必须了解其确切的机制。本研究的目的是探讨不同激光波长对静脉内激光治疗的影响。本研究采用980 nm二极管激光器和1070 nm光纤激光器。以8w和10w的980 nm和1070 nm激光照射人体静脉,找出最佳功率和波长。激光应用后,观察到明显的收缩。两种激光类型的静脉内径和外径也变窄。10w的980 nm激光应用,收缩效果更好。
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引用次数: 2
Feasibility of head imaging using multi-frequency magnetic induction tomography 头颅多频磁感应断层成像的可行性
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130378
D. Gursoy, H. Scharfetter
Magnetic induction tomography (MİT) is a low resolution imaging modality which attempts to reconstruct the electrical conductivity distribution in the body. In MİT, eddy currents are induced within the body via transMİTter coils and the magnetic field of these currents are measured by an array of receiver coils encircling the body. The multi-frequency excitation perMİTs imaging of motionless organs like the brain, since the frequency dependence of the biological tissue conductivities. In this work, the feasibility of the head imaging using multi-frequency MİT was investigated using a multi-shell spherical head model. The excitaion frequency was chosen from 10 kHz to 10 MHz which covers the β-dispersion region of the biological tissues of interest and the conductivities for the head tissues were assigned based on a Cole model. Moreover, the bleeding in head was modeled and the recostructed head images were presented.
磁感应断层扫描(MİT)是一种低分辨率成像方式,它试图重建体内的电导率分布。在MİT中,涡流是通过transMİTter线圈在体内产生的,这些电流的磁场是通过环绕身体的一系列接收器线圈来测量的。多频激发perMİTs成像静止的器官,如大脑,由于频率依赖于生物组织的电导率。在这项工作中,研究了使用多壳球头模型进行多频MİT头部成像的可行性。激励频率选择在10 kHz ~ 10 MHz范围内,覆盖目标生物组织的β-色散区,并根据Cole模型对头部组织的电导率进行分配。在此基础上,对头部出血进行了建模,并给出了重建的头部图像。
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引用次数: 0
3D blood flow simulations in human arterial tree bifurcations 人体动脉树分叉的三维血流模拟
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130389
E. Aribas, S. Piskin, M. S. Çelebi
This paper intends to simulate 3D blood flow of carotid artery bifurcations using a suitable geometrical model with the help of various processing tools and methods. To understand flow characteristics of human blood flow, it is essential to model 3D human arterial tree with as many branches as possible. Geometric modeling of the artery network is structured using a commercial program (Mimics). Conversion of the medical raw data to the geometrical model requires preprocessing tools and software in order to clean the distorted data or irregular data. This step is handled by using Mimics Medical Graphics Software. Next step is conversion of geometric model to a flow model including the crucial preprocessing operation using TGrid which is a commercial preprocessing program. Further, computational grid generation methods are applied to enhance the flow model. In addition to that, for future work it is made possible to add more bifurcations on the computational model. Exporting the geometrical data into a well-known fluid solver (Fluent) requires certain group of simulations and analysis. Therefore, a source mesh file is created for initial simulations that include 3D steady, unsteady (transient) flows with upstream velocities in constant and sinus wave form. All cases are compared according to pressure, shear stress and velocity values.
本文拟利用各种加工工具和方法,采用合适的几何模型模拟颈动脉分支的三维血流。为了了解人体血流的流动特性,有必要建立具有尽可能多分支的三维人体动脉树模型。使用商业程序(Mimics)构建动脉网络的几何建模。将医学原始数据转换为几何模型需要预处理工具和软件,以清除畸变数据或不规则数据。这一步是通过使用Mimics医学图形软件处理的。下一步是将几何模型转换为流模型,其中包括使用商用预处理程序TGrid进行关键的预处理操作。进一步,应用计算网格生成方法对流动模型进行增强。除此之外,对于未来的工作,可以在计算模型上添加更多的分岔。将几何数据导出到著名的流体求解器(Fluent)中需要进行一定的模拟和分析。因此,为初始模拟创建了源网格文件,包括三维稳定,非稳定(瞬态)流动,上游速度为恒定和窦波形式。根据压力、剪应力和速度值对所有情况进行比较。
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引用次数: 4
The bioinformatics tools for the estimation of disordered regions in proteins 蛋白质无序区估计的生物信息学工具
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130377
Onur Imer, Levent Çavaş
Estimation of disordered regions in proteins as a measurement of flexibility is important in terms of playing key roles in regulation of transcription and translation, protein-protein, protein-DNA interactions and also in determining the tertiary structure of the proteins. It has been determined that proteins that include intensive amounts of aminoacids such as alanine, glycine and proline have propensity of disorder on account of changing Φ and Ψ bond angles. In this study, two proteins, one with high propensity of disorder and the other with low propensity of disorder, have been chosen to emphasize the differences between them. The disordered regions in two important enzymes (DNA-topoisomerase I and glutathione peroxidase 5) chosen from the protein bank of ExPasy (Expert Protein Analysis System) have been estimated by using 5 newly developed bioinformatics tools (RONN, FoldIndex, VSL2 DisProt, GlobPlot, DisEMBL). Some proteins that include disordered regions have been related to some metabolic diseases such as diabetes, cancer, Alzheimer. The main aim of this study is to introduce the developed bioinformatics tools related to disordered regions in two selected proteins.
在转录和翻译、蛋白质-蛋白质、蛋白质- dna相互作用以及确定蛋白质的三级结构方面,对蛋白质中无序区域的估计作为一种测量灵活性的重要方法在发挥关键作用方面发挥重要作用。已经确定,含有大量氨基酸(如丙氨酸、甘氨酸和脯氨酸)的蛋白质由于改变Φ和Ψ键角而具有无序倾向。在本研究中,选择了两种蛋白质,一种具有高障碍倾向,另一种具有低障碍倾向,以强调它们之间的差异。利用5种新开发的生物信息学工具(RONN, FoldIndex, VSL2 DisProt, GlobPlot, DisEMBL),对ExPasy (Expert protein Analysis System)蛋白库中选取的两种重要酶(dna拓扑异构酶I和谷胱甘肽过氧化物酶5)的紊乱区域进行了估计。一些包含紊乱区域的蛋白质与一些代谢疾病有关,如糖尿病、癌症、阿尔茨海默病。本研究的主要目的是介绍已开发的生物信息学工具与两种选定的蛋白质的无序区域有关。
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引用次数: 3
Classification of 4-class motor imagery EEG data with Common Sparse Spectral Spatial Pattern method 基于公共稀疏频谱空间模式的四类运动图像脑电数据分类
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130261
Berna Akinci, N. G. Gencer
Brain Computer Interface aims to provide a communication system with external media via thougths. For this purpose, brain signals are acquired from the scalp by EEG device and processed for characterization. In this work, the classification of movement imagery EEG data has been studied for left hand, right hand, foot and tongue movement imagination cases. Common Spatial Patterns (CSP) method and temporal filters have been used in classification and Common Sparse Spectral Spatial Patterns (CSSSP) method has been tried on 4-class motor imagery data in order to improve the accuracy for classification.
脑机接口旨在通过思想提供与外界媒介的通信系统。为此,EEG设备从头皮获取脑信号,并对其进行特征处理。本文研究了左手、右手、脚和舌头运动想象病例的运动图像脑电数据分类。为了提高分类的精度,将公共空间模式(Common Spatial Patterns, CSP)方法和时间滤波器用于分类,并在4类运动图像数据上尝试了公共稀疏光谱空间模式(Common Sparse Spectral Spatial Patterns, CSSSP)方法。
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引用次数: 2
Brain MR image segmentation with fuzzy C-means and using additional shape elements 基于模糊c均值和附加形状元素的脑MR图像分割
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130271
O. Ozyurt, A. Dinçer, C. Ozturk
Using the intensity of the element in interest, standard FCM generates the membership values to all classes. When used for segmentation of images, this method is not capable of correcting the effects of noise. To overcome that problem, we propose a modification on the standard method. The voxels in the neighborhood are taken into account, forming the shape elements in additon to the intensity of the voxel in interest. The resulting input vector is used with FCM. The proposed method was tested with MR brain image with and without added syntetic noise.
使用感兴趣元素的强度,标准FCM生成所有类的成员值。当用于图像分割时,该方法不能校正噪声的影响。为了克服这个问题,我们提出对标准方法进行修改。除了感兴趣的体素的强度外,还考虑了邻域中的体素,形成形状元素。得到的输入向量与FCM一起使用。用添加和不添加合成噪声的脑磁共振图像对该方法进行了测试。
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引用次数: 2
Postural control strategies enlightened by the usage of tendon vibration technique 肌腱振动技术对姿态控制策略的启示
Pub Date : 2009-05-20 DOI: 10.1109/BIYOMUT.2009.5130299
S. Gurses
Postural control strategies applied by a subject in two different physical environments (phy env) were explored by using tendon vibration technique. EMG data from left and right Tibialis Anterior and Gastrocnemius muscles have been received from a subject while standing still on a force platform in two different conditions (eyes open and closed) during 180 sec long trials at the phy env's created. The subject received two 10 sec long 80 Hz vibrations applied to left and right Achilles tendon at 50th and 120th secs of the data collection. It has been observed that the subject experienced a motion illusion in the condition where his feet bore his total body weight with eyes closed (phy env I), which has been revealed through the analyses of Center-of-Pressure (CoPx) and EMG data. However, when 7% of his body weight was suspended to the ceiling through a harness (phy env II) the illusion disappeared and the variability in the CoPx signal decreased.
利用肌腱振动技术探讨了受试者在两种不同物理环境(物理环境)下的体位控制策略。在180秒的实验中,受试者在两种不同的条件下(睁眼和闭眼)站在力平台上静止不动时,接受了左右胫骨前肌和腓肠肌的肌电图数据。在数据收集的第50秒和120秒,受试者接受两次10秒长80赫兹的振动,施加于左右跟腱。通过对压力中心(CoPx)和肌电图数据的分析,研究人员观察到,受试者在闭着眼睛的情况下,在双脚承受全身重量的情况下(物理环境I)会产生运动错觉。然而,当他的体重的7%通过吊带悬挂在天花板上时(物理环境II),这种错觉消失了,CoPx信号的可变性减少了。
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引用次数: 0
期刊
2009 14th National Biomedical Engineering Meeting
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