首页 > 最新文献

Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi最新文献

英文 中文
Histerosalpingografide Kullanılan İyotlu Kontrast Maddenin Vücut Sıcaklığında ya da Oda Sıcaklığında Uygulanmasının Vizüel Analog Skala Skorlarına Etkisi
Pub Date : 2022-10-23 DOI: 10.38136/jgon.1139732
Burak Ersak, Yasemin Taşçi, Rahime BEDİR FINDIK, Duygu TUĞRUL ERSAK, A. Tokmak, Mahmut Kuntay Kokanalı
Aim: To compare pain scores of infertile patients during and after hysterosalpingography (HSG) procedure using visual analoge scale (VAS) between cold and warm contrast medium and to investigate whether using warm contrast can alter spontaneous pregnancy rate. Materials and Methods: Prospective randomized study between March-September 2017. Primary infertile patients undergoing HSG procedure. Patients’ age, body mass index (BMI), history of previous surgery, duration of infertility and pain levels during the most painful menstrual period were recorded. The pain severity was questioned during and at the 30th minute after the procedure using VAS. While patients who underwent HSG using a contrast medium at body temperature 37 °C were defined as warm group(n:55), patients who underwent HSG using a contrast medium at room temperature 23 °C were defined as cold group (n:55). Results: There were no significant differences between the groups in terms of age, BMI, duration of infertility, previous surgery and VAS during menstruation. The mean duration of HSG of warm group patients was significantly lower(p=0.001). Warm group patients’ mean VAS score during and 30 minutes after HSG were significantly lower than in the control group ( 5.3±4.2 vs 7.5±2.0), (1.1±0.9 vs 2.4±1.4), respectively. While severe pain percentage during HSG in warm group was 25.5%, it was 66.7% in the control group. In logistic regression analysis, warm and cold groups were only found as significant related factors for severe pain felt during procedure (p
目的:应用视觉模拟评分法(VAS)比较冷、热造影剂对不孕患者在子宫输卵管造影(HSG)术中及术后疼痛评分的影响,探讨热造影剂对自然妊娠率的影响。材料和方法:2017年3月- 9月的前瞻性随机研究。接受生殖细胞移植手术的原发性不孕症患者。记录患者的年龄、体重指数(BMI)、既往手术史、不孕持续时间和最痛月经期疼痛程度。在手术期间和手术后30分钟使用VAS对疼痛严重程度进行询问。在体温37℃下使用造影剂行HSG的患者被定义为温组(n:55),在室温23℃下使用造影剂行HSG的患者被定义为冷组(n:55)。结果:两组患者在年龄、BMI、不孕持续时间、既往手术及月经期间VAS评分均无显著差异。温组患者HSG的平均持续时间显著低于温组(p=0.001)。温组患者HSG时和术后30min VAS平均评分均显著低于对照组(5.3±4.2 vs 7.5±2.0)、(1.1±0.9 vs 2.4±1.4)。热组在HSG过程中剧烈疼痛的比例为25.5%,对照组为66.7%。在logistic回归分析中,温热组和冷组仅被发现为手术过程中感受到的严重疼痛的显著相关因素(p
{"title":"Histerosalpingografide Kullanılan İyotlu Kontrast Maddenin Vücut Sıcaklığında ya da Oda Sıcaklığında Uygulanmasının Vizüel Analog Skala Skorlarına Etkisi","authors":"Burak Ersak, Yasemin Taşçi, Rahime BEDİR FINDIK, Duygu TUĞRUL ERSAK, A. Tokmak, Mahmut Kuntay Kokanalı","doi":"10.38136/jgon.1139732","DOIUrl":"https://doi.org/10.38136/jgon.1139732","url":null,"abstract":"Aim: To compare pain scores of infertile patients during and after hysterosalpingography (HSG) procedure using visual analoge scale (VAS) between cold and warm contrast medium and to investigate whether using warm contrast can alter spontaneous pregnancy rate. \u0000Materials and Methods: Prospective randomized study between March-September 2017. Primary infertile patients undergoing HSG procedure. Patients’ age, body mass index (BMI), history of previous surgery, duration of infertility and pain levels during the most painful menstrual period were recorded. The pain severity was questioned during and at the 30th minute after the procedure using VAS. While patients who underwent HSG using a contrast medium at body temperature 37 °C were defined as warm group(n:55), patients who underwent HSG using a contrast medium at room temperature 23 °C were defined as cold group (n:55). \u0000Results: There were no significant differences between the groups in terms of age, BMI, duration of infertility, previous surgery and VAS during menstruation. The mean duration of HSG of warm group patients was significantly lower(p=0.001). Warm group patients’ mean VAS score during and 30 minutes after HSG were significantly lower than in the control group ( 5.3±4.2 vs 7.5±2.0), (1.1±0.9 vs 2.4±1.4), respectively. While severe pain percentage during HSG in warm group was 25.5%, it was 66.7% in the control group. In logistic regression analysis, warm and cold groups were only found as significant related factors for severe pain felt during procedure (p","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130858531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spermatozoa Kryoprezervasyonunda Epigenetik Değişiklikler
Pub Date : 2022-10-23 DOI: 10.38136/jgon.1186821
Mehmet Caner Özer
Spermatozoa kriyoprezervasyon teknolojisi, erkek fertilitesi için en çok kullanılan koruma protokolüdür. Erkek doğurganlığının yönetimi, kanser tedavisi, vazektomi veya cerrahi infertilite tedavilerinden önce donör spermlerini depolamak ve korumak için kullanılmaktadır. Epigenetik yeniden programlamanın embriyonik gelişimde hayati bir rol oynadığı bildirilmiştir ve birkaç çalışma, kusurlu epigenetik yeniden programlamanın anormal fetal büyüme, kanser ve diyabet gibi hastalıklar ile ilişkili olduğunu göstermiştir. Yapısal ve fizyolojik değişikliklerin yanı sıra, spermatozoadaki gen ve proteinlerin ekspresyonunun, mRNA stabilitesinin ve epigenetik içeriğin donma-çözme işleminden etkilenebileceği bildirilmektedir. Dondurulmuş-çözülmüş spermatozoadaki bu değişiklikler doğurganlık potansiyelini ve embriyo gelişimini etkileyebilmektedir. Kriyoprezervasyonda toksisite, epigenetik stabilite, mikrobiyal kontaminasyon gibi birden fazla güvenlik sorunu vardır. Bu sorunlardan epigenetik stabilite ve dondurulmuş spermatozoa ile doğan çocukların sağlığı üzerindeki kriyoprezervasyonun etkileri hakkında çok az bilgi vardır. Bu derlemede, kriyoprezervasyon sırasında spermlerdeki değişiklikler ve epigenetik modifikasyonları hakkındaki makaleler özetlenmiştir.
精子冷冻保存技术是应用最广泛的男性生育力保存方案。它用于男性生育管理,在癌症治疗、输精管结扎术或不育症手术治疗前储存和保存捐献者的精子。据报道,表观遗传学重编程在胚胎发育中起着至关重要的作用,多项研究表明,表观遗传学重编程缺陷与胎儿发育异常、癌症和糖尿病等疾病有关。据报道,除了结构和生理变化外,冻融还会影响精子中基因和蛋白质的表达、mRNA 的稳定性和表观遗传学内容。冷冻解冻精子中的这些变化可能会影响生育潜能和胚胎发育。冷冻保存存在多种安全问题,如毒性、表观遗传稳定性和微生物污染。在这些问题中,人们对表观遗传稳定性以及冷冻保存对冷冻精子所生儿童健康的影响知之甚少。在这篇综述中,我们总结了有关精子在冷冻保存过程中的变化及其表观遗传学修饰的文章。
{"title":"Spermatozoa Kryoprezervasyonunda Epigenetik Değişiklikler","authors":"Mehmet Caner Özer","doi":"10.38136/jgon.1186821","DOIUrl":"https://doi.org/10.38136/jgon.1186821","url":null,"abstract":"Spermatozoa kriyoprezervasyon teknolojisi, erkek fertilitesi için en çok kullanılan koruma protokolüdür. Erkek doğurganlığının yönetimi, kanser tedavisi, vazektomi veya cerrahi infertilite tedavilerinden önce donör spermlerini depolamak ve korumak için kullanılmaktadır. Epigenetik yeniden programlamanın embriyonik gelişimde hayati bir rol oynadığı bildirilmiştir ve birkaç çalışma, kusurlu epigenetik yeniden programlamanın anormal fetal büyüme, kanser ve diyabet gibi hastalıklar ile ilişkili olduğunu göstermiştir. Yapısal ve fizyolojik değişikliklerin yanı sıra, spermatozoadaki gen ve proteinlerin ekspresyonunun, mRNA stabilitesinin ve epigenetik içeriğin donma-çözme işleminden etkilenebileceği bildirilmektedir. Dondurulmuş-çözülmüş spermatozoadaki bu değişiklikler doğurganlık potansiyelini ve embriyo gelişimini etkileyebilmektedir. Kriyoprezervasyonda toksisite, epigenetik stabilite, mikrobiyal kontaminasyon gibi birden fazla güvenlik sorunu vardır. Bu sorunlardan epigenetik stabilite ve dondurulmuş spermatozoa ile doğan çocukların sağlığı üzerindeki kriyoprezervasyonun etkileri hakkında çok az bilgi vardır. Bu derlemede, kriyoprezervasyon sırasında spermlerdeki değişiklikler ve epigenetik modifikasyonları hakkındaki makaleler özetlenmiştir.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"163 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133118386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disseminated intravascular coagulation in obstetric patients: maternal and fetal results 产科患者弥散性血管内凝血:母体和胎儿结果
Pub Date : 2022-10-22 DOI: 10.38136/jgon.1179018
Özgün Ceylan, A. Çağlar
AIM: In our study, it was aimed to obtain guiding information to prevent complications that may develop in advance and to decrease maternal and fetal morbidity and mortality by evaluating the antepartum of patients who developed DIC due to obstetric reasons. MATERIALS AND METHODS: Obstetric patients who were hospitalized in obstetrics and perinatology clinics and developed disseminated intravascular coagulation (DIC) were retrospectively analyzed. DIC scoring of the patients was made according to the International Society on Thrombosis and Haemostasis (ISTH) criteria. Maternal and fetal outcomes from the patients were documented. RESULTS: During the 6-year period in which the data were analyzed, DIC was detected in 57 pregnants out of 108281 deliveries, and the incidence of DIC was found to be 0.052%. The categories of pregnancy complication preceding DIC: placental invasion and implantation anomalies, postpartum hemorrhage (atonia), placental abruption, hypertensive disease of pregnancy and others were found. Its rate in maternal morbidity was 38.6% and maternal mortality rate was 1.75% with 1 patient. 35% of the patients had laparotomy / re-laparotomy and 21% of these patients had hysterectomy. The average birth weight of the newborn is 2341.3 grams. Neonatal intensive care need is 34.5%, stillbirth rate is 25.5%. Neonatal mortality rate was determined as 3.6%. CONCLUSION: The management scheme plays a key role in delivery because termination of pregnancy often eliminates the underlying obstetric disorder. Early diagnosis and active treatment protocols reduce mortality and morbidity. Because of the physiological changes seen in the coagulation cascade during pregnancy, using a pregnancy-specific DIC score instead of the ISTH DIC score developed for non-pregnant adults may facilitate diagnosis.
目的:本研究旨在通过对产科原因导致DIC患者的产前评估,为提前预防可能发生的并发症,降低母胎发病率和死亡率提供指导性信息。材料与方法:回顾性分析在产科和围产儿门诊住院并发生弥散性血管内凝血(DIC)的产科患者。根据国际血栓与止血学会(ISTH)标准对患者进行DIC评分。记录了患者的母胎结局。结果:在数据分析的6年期间,108281例分娩中有57例孕妇检出DIC, DIC的发生率为0.052%。DIC前妊娠并发症类型:胎盘侵犯及着床异常、产后出血(弛缓)、胎盘早剥、妊娠期高血压疾病等。产妇发病率为38.6%,死亡率为1.75%(1例)。35%的患者进行了开腹/再开腹手术,21%的患者进行了子宫切除术。新生儿的平均出生体重为2341.3克。新生儿重症监护需求为34.5%,死胎率为25.5%。新生儿死亡率确定为3.6%。结论:管理方案在分娩中起着关键作用,因为终止妊娠往往可以消除潜在的产科疾病。早期诊断和积极治疗方案可降低死亡率和发病率。由于妊娠期间凝血级联的生理变化,使用妊娠特异性DIC评分代替为非妊娠成人开发的ISTH DIC评分可能有助于诊断。
{"title":"Disseminated intravascular coagulation in obstetric patients: maternal and fetal results","authors":"Özgün Ceylan, A. Çağlar","doi":"10.38136/jgon.1179018","DOIUrl":"https://doi.org/10.38136/jgon.1179018","url":null,"abstract":"AIM: In our study, it was aimed to obtain guiding information to prevent complications that may develop in advance and to decrease maternal and fetal morbidity and mortality by evaluating the antepartum of patients who developed DIC due to obstetric reasons. \u0000MATERIALS AND METHODS: Obstetric patients who were hospitalized in obstetrics and perinatology clinics and developed disseminated intravascular coagulation (DIC) were retrospectively analyzed. DIC scoring of the patients was made according to the International Society on Thrombosis and Haemostasis (ISTH) criteria. Maternal and fetal outcomes from the patients were documented. \u0000RESULTS: During the 6-year period in which the data were analyzed, DIC was detected in 57 pregnants out of 108281 deliveries, and the incidence of DIC was found to be 0.052%. The categories of pregnancy complication preceding DIC: placental invasion and implantation anomalies, postpartum hemorrhage (atonia), placental abruption, hypertensive disease of pregnancy and others were found. Its rate in maternal morbidity was 38.6% and maternal mortality rate was 1.75% with 1 patient. 35% of the patients had laparotomy / re-laparotomy and 21% of these patients had hysterectomy. The average birth weight of the newborn is 2341.3 grams. Neonatal intensive care need is 34.5%, stillbirth rate is 25.5%. Neonatal mortality rate was determined as 3.6%. \u0000CONCLUSION: The management scheme plays a key role in delivery because termination of pregnancy often eliminates the underlying obstetric disorder. Early diagnosis and active treatment protocols reduce mortality and morbidity. Because of the physiological changes seen in the coagulation cascade during pregnancy, using a pregnancy-specific DIC score instead of the ISTH DIC score developed for non-pregnant adults may facilitate diagnosis.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133540565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Maternal Weight-gain During Pregnancy on Neonatal TSH Results 孕妇孕期体重增加对新生儿TSH结果的影响
Pub Date : 2022-10-17 DOI: 10.38136/jgon.973086
Özge Torun, R. Dut, Zuhal AYDAN SAĞLAM, S. Cömert
Amaç: Annenin gebelik döneminde kilo artışının yenidoğanın ölçülen ilk TSH düzeyleri üzerine etkisini araştırmaktır. Gereçler: Güngören 30 Ağustos Aile Sağlığı Merkezinde; takip edilen 112 gebe ve bu gebelerin 112 bebeği retrospektif olarak incelendi. Gebelerin boy, kilo ölçümleri ve vücut kitle indekslerinin (VKİ) hesaplandığı gebelik haftaları, bebeklerin doğum tartıları ve TSH değerleri alındı. Gebeler, normal (VKİ
目的研究孕期母体体重增加对新生儿首次 TSH 水平测量的影响。研究材料对 Güngören 8 月 30 日家庭医疗中心随访的 112 名孕妇和 112 名婴儿进行回顾性分析。测量了孕妇的身高和体重、计算体重指数(BMI)的孕周、婴儿的出生体重和 TSH 水平。孕妇被分为正常(BMI
{"title":"The Effects of Maternal Weight-gain During Pregnancy on Neonatal TSH Results","authors":"Özge Torun, R. Dut, Zuhal AYDAN SAĞLAM, S. Cömert","doi":"10.38136/jgon.973086","DOIUrl":"https://doi.org/10.38136/jgon.973086","url":null,"abstract":"Amaç: Annenin gebelik döneminde kilo artışının yenidoğanın ölçülen ilk TSH düzeyleri üzerine etkisini araştırmaktır. \u0000Gereçler: Güngören 30 Ağustos Aile Sağlığı Merkezinde; takip edilen 112 gebe ve bu gebelerin 112 bebeği retrospektif olarak incelendi. Gebelerin boy, kilo ölçümleri ve vücut kitle indekslerinin (VKİ) hesaplandığı gebelik haftaları, bebeklerin doğum tartıları ve TSH değerleri alındı. Gebeler, normal (VKİ","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"164 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128511797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DİFÜZYON AĞIRLIKLI MANYETİK REZONANS İNCELEMENİN SERVİKS KANSERİ TANISI VE PATOLOJİK TİPLENDİRİLMESİNDEKİ YERİ
Pub Date : 2022-10-04 DOI: 10.38136/jgon.1082790
Ezel YALTIRIK BİLGİN, Nazan Çiledağ, Koray Aslan
Amaç:. Diffüzyon ağırlıklı manyetik rezonans inceleme, serviks kanseri görüntülemesinde önemli bir yöntemdir. Biz de çalışmamızda difüzyon ağırlıklı incelemede hesaplanan ADC değerlerinin normal serviks dokusu ile serviks kanseri arasındaki farklılıklarını ve serviks kanseri patolojik tipleri ayırıcı tanısındaki önemini değerlendirmeyi amaçladık. Gereçler ve Yöntem: Merkezimize Ocak 2018- Ocak 2022 tarihleri arasında başvuran tanısı histopatolojik olarak kanıtlanmış 40 hasta(çalışma grubu) ve aynı tarihler arasında, servikal kanser şüphesi olmaksızın başka nedenlerden pelvik MR çekilen 40 hasta(kontrol grubu) retrospektif olarak değerlendirilerek çalışmaya dahil edildi. Hastaların yaşları ve patolojik tanıları değerlendirilip oluşturulan ADC haritalarından ADC değer ölçümleri yapıldı. Bulgular: Serviks kanseri tanılı hastaların ortalama ADC değeri 0.93(±0.28) x10-3 mm2/s, olarak saptanırken, kontrol grubunda ortalama ADC değeri 1.61(±0.32) x 10-3 mm2/s olarak hesaplandı. Kontrol grubuna kıyasla serviks kanseri tanılı hastalarda ADC skor ortalaması istatistiksel olarak anlamlı derecede daha düşük olduğu saptandı(t=10.339, p=
目的弥散加权磁共振成像是宫颈癌成像的一种重要方法。在我们的研究中,我们旨在评估正常宫颈组织与宫颈癌之间的差异,以及弥散加权成像中计算的 ADC 值在宫颈癌病理类型鉴别诊断中的重要性。 材料与方法:在 2018 年 1 月至 2022 年 1 月期间,对 40 例经组织病理学确诊的患者(研究组)和 40 例因其他原因接受盆腔 MRI 检查但未怀疑宫颈癌的患者(对照组)进行回顾性评估并纳入研究。对患者的年龄和病理诊断进行评估,并根据 ADC 图测量 ADC 值。结果宫颈癌患者的平均 ADC 值为 0.93(±0.28) x 10-3 mm2/s,而对照组的平均 ADC 值为 1.61(±0.32) x 10-3 mm2/s。与对照组相比,宫颈癌患者的平均 ADC 值在统计学上明显较低(t=10.339,p=0.05)。
{"title":"DİFÜZYON AĞIRLIKLI MANYETİK REZONANS İNCELEMENİN SERVİKS KANSERİ TANISI VE PATOLOJİK TİPLENDİRİLMESİNDEKİ YERİ","authors":"Ezel YALTIRIK BİLGİN, Nazan Çiledağ, Koray Aslan","doi":"10.38136/jgon.1082790","DOIUrl":"https://doi.org/10.38136/jgon.1082790","url":null,"abstract":"Amaç:. Diffüzyon ağırlıklı manyetik rezonans inceleme, serviks kanseri görüntülemesinde önemli bir yöntemdir. Biz de çalışmamızda difüzyon ağırlıklı incelemede hesaplanan ADC değerlerinin normal serviks dokusu ile serviks kanseri arasındaki farklılıklarını ve serviks kanseri patolojik tipleri ayırıcı tanısındaki önemini değerlendirmeyi amaçladık. \u0000Gereçler ve Yöntem: Merkezimize Ocak 2018- Ocak 2022 tarihleri arasında başvuran tanısı histopatolojik olarak kanıtlanmış 40 hasta(çalışma grubu) ve aynı tarihler arasında, servikal kanser şüphesi olmaksızın başka nedenlerden pelvik MR çekilen 40 hasta(kontrol grubu) retrospektif olarak değerlendirilerek çalışmaya dahil edildi. Hastaların yaşları ve patolojik tanıları değerlendirilip oluşturulan ADC haritalarından ADC değer ölçümleri yapıldı. \u0000Bulgular: Serviks kanseri tanılı hastaların ortalama ADC değeri 0.93(±0.28) x10-3 mm2/s, olarak saptanırken, kontrol grubunda ortalama ADC değeri 1.61(±0.32) x 10-3 mm2/s olarak hesaplandı. Kontrol grubuna kıyasla serviks kanseri tanılı hastalarda ADC skor ortalaması istatistiksel olarak anlamlı derecede daha düşük olduğu saptandı(t=10.339, p=","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127687967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of laparoscopy and laparotomy in endometrial carcinoma 腹腔镜与开腹手术治疗子宫内膜癌的比较
Pub Date : 2022-10-04 DOI: 10.38136/jgon.1057879
Ali Oğuzhan Hati̇poğlu, Serhan İscan, İ. Güler, Haldun Güner
Amaç: Endometrium kanseri; Türkiye, Amerika ve Avrupa'da kadınlarda en sık görülen jinekolojik malignensidir. Genel olarak kadınlar yaşamları boyunca endomertium kanserine yakalanma riski %3-4’tür. Tedavi ve evrelemesi cerrahi olarak yapılan endometrium kanserinde cerrahi olarak seçilen genel yöntem açık cerrahidir. Çalışma; endometrium kanserinin evreleme ve tedavisinde laparotomi ile laparoskopiyi karşılaştırmayı amaçlamaktadır. Gereç ve Yöntemler: Endometrium kanseri nedeniyle evreleme cerrahisi yapılan 57 hastanın 29’unda cerrahi laparoskopik olarak, 28’inde cerrahi laparotomik olarak gerçekleştirildi. Laparoskopi grubu ile laparotomi grubunun; yaş, vücut kitle indeksi, perioperatif ve postoperatif komplikasyonları, çıkarılan lenf nodu sayıları, operasyon süresi ve hastanede kalış süresi, cerrahiye giriş ve çıkış hemoglobin değerleri karşılaştırıldı. Bulgular: Gruplar, demografik, maternal ve antropometrik açıdan değerlendirildiğinde homojen yapıda oldukları izlendi. Yalnızca laparotomik grupta parite laparoskopik gruba göre istatiksel olarak anlamlı derecede fazlaydı, gravidalar arasında fark yoktu. Operasyon süreleri, tahmini kan kayıpları, preoperatif, postoperatif hemoglobin düzeyleri, intraoperatif, ve postoperatif komplikasyonlar açısından laparoskopi ve laparotomi arasında fark saptanmadı. Laparoskopi grubunda hastanede kalış süresi anlamlı olarak kısa saptandı. Lenf nodu disseksiyonunda çıkarılan lenf bezi sayısı laparotomik cerrahide daha fazlaydı. Sonuç: Laparoskopik cerrahi endometrium kanserinde güvenilir ve uygulanabilir bir cerrahi yöntemidir. Hastanede kalış süresini azaltması, günlük yaşama çabuk dönüş avantajı olarak gözükmektedir. Buna karşı daha agresif lenf nodu disseksiyonu gerektiren ileri evre, yüksek grade, agresif tip kanserlerde, daha az lenf nodu çıkarılması dezavantaj olabilir.
目的:子宫内膜癌是土耳其、美国和欧洲妇女最常见的妇科恶性肿瘤:子宫内膜癌是土耳其、美国和欧洲妇女最常见的妇科恶性肿瘤。一般来说,妇女一生中患子宫内膜癌的风险为 3-4%。子宫内膜癌的治疗和分期是通过手术进行的,一般选择的手术方法是开腹手术。本研究旨在比较开腹手术和腹腔镜手术在子宫内膜癌分期和治疗中的应用。材料和方法:在接受子宫内膜癌分期手术的 57 名患者中,29 人接受了腹腔镜手术,28 人接受了开腹手术。比较了腹腔镜手术组和开腹手术组的年龄、体重指数、围手术期和术后并发症、切除淋巴结数量、手术和住院时间以及手术开始和结束时的血红蛋白值。结果两组的人口统计学特征、产妇特征和人体测量特征相同。与腹腔镜组相比,只有腹腔镜组的胎次在统计学上明显较高,但孕产妇之间没有差异。腹腔镜手术和开腹手术在手术时间、估计失血量、术前和术后血红蛋白水平、术中和术后并发症方面没有差异。腹腔镜手术组的住院时间明显较短。腹腔镜组在淋巴结清扫中切除的淋巴结数量较多。结论腹腔镜手术是一种安全可行的子宫内膜癌手术方法。缩短住院时间和快速恢复日常生活似乎是其优势所在。另一方面,对于需要进行更积极的淋巴结清扫的晚期、高级别、侵袭性癌症来说,淋巴结切除较少可能是一个不利因素。
{"title":"Comparison of laparoscopy and laparotomy in endometrial carcinoma","authors":"Ali Oğuzhan Hati̇poğlu, Serhan İscan, İ. Güler, Haldun Güner","doi":"10.38136/jgon.1057879","DOIUrl":"https://doi.org/10.38136/jgon.1057879","url":null,"abstract":"Amaç: Endometrium kanseri; Türkiye, Amerika ve Avrupa'da kadınlarda en sık görülen jinekolojik malignensidir. Genel olarak kadınlar yaşamları boyunca endomertium kanserine yakalanma riski %3-4’tür. Tedavi ve evrelemesi cerrahi olarak yapılan endometrium kanserinde cerrahi olarak seçilen genel yöntem açık cerrahidir. Çalışma; endometrium kanserinin evreleme ve tedavisinde laparotomi ile laparoskopiyi karşılaştırmayı amaçlamaktadır. Gereç ve Yöntemler: Endometrium kanseri nedeniyle evreleme cerrahisi yapılan 57 hastanın 29’unda cerrahi laparoskopik olarak, 28’inde cerrahi laparotomik olarak gerçekleştirildi. Laparoskopi grubu ile laparotomi grubunun; yaş, vücut kitle indeksi, perioperatif ve postoperatif komplikasyonları, çıkarılan lenf nodu sayıları, operasyon süresi ve hastanede kalış süresi, cerrahiye giriş ve çıkış hemoglobin değerleri karşılaştırıldı. Bulgular: Gruplar, demografik, maternal ve antropometrik açıdan değerlendirildiğinde homojen yapıda oldukları izlendi. Yalnızca laparotomik grupta parite laparoskopik gruba göre istatiksel olarak anlamlı derecede fazlaydı, gravidalar arasında fark yoktu. Operasyon süreleri, tahmini kan kayıpları, preoperatif, postoperatif hemoglobin düzeyleri, intraoperatif, ve postoperatif komplikasyonlar açısından laparoskopi ve laparotomi arasında fark saptanmadı. Laparoskopi grubunda hastanede kalış süresi anlamlı olarak kısa saptandı. Lenf nodu disseksiyonunda çıkarılan lenf bezi sayısı laparotomik cerrahide daha fazlaydı. Sonuç: Laparoskopik cerrahi endometrium kanserinde güvenilir ve uygulanabilir bir cerrahi yöntemidir. Hastanede kalış süresini azaltması, günlük yaşama çabuk dönüş avantajı olarak gözükmektedir. Buna karşı daha agresif lenf nodu disseksiyonu gerektiren ileri evre, yüksek grade, agresif tip kanserlerde, daha az lenf nodu çıkarılması dezavantaj olabilir.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130299856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Jinekoloji kliniklerinde ultrasonografi probları ve jeli, bakteriyel enfeksiyonların kaynağı olabilir mi?: Üçüncü basamak bir hastane deneyimi 妇科门诊中的超声探头和凝胶是否会成为细菌感染源:一家三级医院的经验
Pub Date : 2022-09-09 DOI: 10.38136/jgon.1133977
N. Akgün, Aybüke Kevser, Serap Yağcı, Çiğdem Ataman Hatipoğlu, Yusuf Ustun
Background: The aim was to evaluate the bacterial contamination rate of ultrasound probes and gels and the associated nosocomial infection risk. In this way, we aimed to assess whether our ultrasound probe disinfection protocols were effective in reducing the risk of hospital-wide infection. Material and Methods: Forty-eight swab samples were collected from the surfaces of transabdominal (TAP) and transvaginal ultrasound (TVP) probes and adhered to gel bottles, which were then cultured in the microbiology laboratory. In comparison, bacterial contamination of gynecology room door handles (12 swab cultures) was analyzed. These measurements were repeated every week for one month, so that each probe was cultured four times during the study period. Results: Non-pathogenic microorganisms (Staphylococcus epidermidis, S. hominis, S. haemolyticus, S. lugdunensis, Corynebacterium amycolatum, C. aurimucosum) common in human skin flora and the environment and two notable pathogens (Enterobacter cloacae, Escherichia coli) were isolated from the probe cultures. Non-pathogenic organisms (S. epidermidis, S. cohnii) were isolated from gel cultures. Also, no significant differences were also found between groups in contamination rates during various patient examinations and emergencies (p > 0.05). Conclusion: Bacterial contamination was found on ultrasound probes/gels in our department. Although the majority were non-pathogenic microorganisms, two pathogenic microorganisms were also identified. Hospital staff should remember that ultrasound probes can be a tool for bacterial infection and can lead to infectious complications. Decontamination of probes with dry, nonsterile paper towels is a cheap, simple, and effective method that does not damage the device and can also reduce bacterial exposure.
背景:目的是评价超声探头和凝胶的细菌污染率及相关的医院感染风险。通过这种方式,我们的目的是评估我们的超声探头消毒方案是否有效地降低了全院感染的风险。材料与方法:从经腹超声(TAP)和经阴道超声(TVP)探针表面收集48份拭子样本,贴于凝胶瓶上,在微生物实验室培养。对比分析了妇科门把手的细菌污染(12个拭子培养)。这些测量每周重复一次,持续一个月,使每个探针在研究期间培养四次。结果:从探针培养物中分离出人体皮肤菌群和环境中常见的非致病性微生物(表皮葡萄球菌、人型葡萄球菌、溶血葡萄球菌、lugdunensis、amycolatum棒状杆菌、金黄色葡萄球菌)和2种显著致病菌(阴沟肠杆菌、大肠杆菌)。从凝胶培养中分离出非致病性生物(表皮葡萄球菌、柯氏葡萄球菌)。不同患者检查和急诊期间的污染率组间差异无统计学意义(p > 0.05)。结论:我科超声探头/凝胶存在细菌污染。虽然大多数是非致病微生物,但也鉴定出两种致病微生物。医院工作人员应该记住,超声探头可能是细菌感染的工具,并可能导致感染性并发症。用干燥的、非无菌的纸巾去污探针是一种便宜、简单、有效的方法,不会损坏设备,还可以减少细菌的接触。
{"title":"Jinekoloji kliniklerinde ultrasonografi probları ve jeli, bakteriyel enfeksiyonların kaynağı olabilir mi?: Üçüncü basamak bir hastane deneyimi","authors":"N. Akgün, Aybüke Kevser, Serap Yağcı, Çiğdem Ataman Hatipoğlu, Yusuf Ustun","doi":"10.38136/jgon.1133977","DOIUrl":"https://doi.org/10.38136/jgon.1133977","url":null,"abstract":"Background: The aim was to evaluate the bacterial contamination rate of ultrasound probes and gels and the associated nosocomial infection risk. In this way, we aimed to assess whether our ultrasound probe disinfection protocols were effective in reducing the risk of hospital-wide infection. \u0000Material and Methods: Forty-eight swab samples were collected from the surfaces of transabdominal (TAP) and transvaginal ultrasound (TVP) probes and adhered to gel bottles, which were then cultured in the microbiology laboratory. In comparison, bacterial contamination of gynecology room door handles (12 swab cultures) was analyzed. These measurements were repeated every week for one month, so that each probe was cultured four times during the study period. \u0000Results: Non-pathogenic microorganisms (Staphylococcus epidermidis, S. hominis, S. haemolyticus, S. lugdunensis, Corynebacterium amycolatum, C. aurimucosum) common in human skin flora and the environment and two notable pathogens (Enterobacter cloacae, Escherichia coli) were isolated from the probe cultures. Non-pathogenic organisms (S. epidermidis, S. cohnii) were isolated from gel cultures. Also, no significant differences were also found between groups in contamination rates during various patient examinations and emergencies (p > 0.05). \u0000Conclusion: Bacterial contamination was found on ultrasound probes/gels in our department. Although the majority were non-pathogenic microorganisms, two pathogenic microorganisms were also identified. Hospital staff should remember that ultrasound probes can be a tool for bacterial infection and can lead to infectious complications. Decontamination of probes with dry, nonsterile paper towels is a cheap, simple, and effective method that does not damage the device and can also reduce bacterial exposure.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134393828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case report: Neonatal Abstinence Syndrome with current literatures 新生儿戒断综合征1例
Pub Date : 2022-09-04 DOI: 10.38136/jgon.1050664
Deniz Yaşar, C. Geyik, Abdullah Yüksel, Oğuzhan Kayar, Nurdan DİNLEN FETTAH
Neonatal abstinence syndrome (NAS) is the withdrawal symptoms that occur in the baby shortly after birth from addicted mother. There are reviews about neonatal abstinence syndrome in the literatures but there is not enough study in Turkey. Literature is include just some case reports from our country. Signs and symptoms in the neonatal period are nonspecific and it is hard to make correct differential diagnosis for NAS without detail anemnesis. Doubt is the key for evaluation NAS. In this article, it is aimed to present the approach of NAS with update literature. We present the follow-up of the baby (born on 32 weeks according to Ballard score) with an unfollowed pregnancy from a heroin and cannabinoid addicted mother. In the treatment process, we mainly use morphine for the withdrawal symptoms. Our clinical approach is diccussed with the current articles.
新生儿戒断综合征(NAS)是婴儿出生后不久由成瘾母亲引起的戒断症状。关于新生儿戒断综合征的文献已有综述,但在土耳其的研究还不够。文献只包括我国的一些病例报告。新生儿期的体征和症状是非特异性的,如果没有详细的贫血,很难对NAS做出正确的鉴别诊断。怀疑是评价NAS的关键。在这篇文章中,它旨在介绍NAS的方法与最新的文献。我们提出了婴儿的随访(出生32周根据巴拉德评分)与一个未跟踪怀孕从海洛因和大麻成瘾的母亲。在治疗过程中,我们主要使用吗啡治疗戒断症状。我们的临床方法与当前的文章进行了讨论。
{"title":"A case report: Neonatal Abstinence Syndrome with current literatures","authors":"Deniz Yaşar, C. Geyik, Abdullah Yüksel, Oğuzhan Kayar, Nurdan DİNLEN FETTAH","doi":"10.38136/jgon.1050664","DOIUrl":"https://doi.org/10.38136/jgon.1050664","url":null,"abstract":"Neonatal abstinence syndrome (NAS) is the withdrawal symptoms that occur in the baby shortly after birth from addicted mother. There are reviews about neonatal abstinence syndrome in the literatures but there is not enough study in Turkey. \u0000Literature is include just some case reports from our country. Signs and symptoms in the neonatal period are nonspecific and it is hard to make correct differential diagnosis for NAS without detail anemnesis. Doubt is the key for evaluation NAS. In this article, it is aimed to present the approach of NAS with update literature. We present the follow-up of the baby (born on 32 weeks according to Ballard score) with an unfollowed pregnancy from a heroin and cannabinoid addicted mother. In the treatment process, we mainly use morphine for the withdrawal symptoms. Our clinical approach is diccussed with the current articles.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121503723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Son Dört Yılda Üçüncü Basamak Hastanemizde Doğumu Gerçekleşen Çoğul Gebelik Sonuçlarının Değerlendirilmesi
Pub Date : 2022-08-22 DOI: 10.38136/jgon.1094804
Özge ŞEHİRLİ KINCI, Mehmet Ferdi Kıncı, Leyla Taştan, Ercan Saruhan, A. A. Sivaslıoğlu
Aim: We aimed to evaluate the outcomes of multiple pregnancies between January 2016 and December 2020 in our hospital, which is a tertiary center. Materials and Methods: 107 multiple pregnancies were included in the study among 6567 pregnant women who were delivered between January 2016 and December 2020 in Muğla University Training and Research Hospital Obstetrics and Gynecology Clinic. Of these retrospectively evaluated pregnant women, 106 were twins and 1 was triplet. Results: It was determined that 87 (80.18%) twin pregnancies were diamniotic-dichorionic, 11 (10.37%) were dichorionic-monoamniotic, and 8 (7.54%) were monochorionic-monoamniotic, respectively. 76 (71.69%) of the deliveries were with preterm delivery and 30 (28.3%) of the pregnant women were delivered at term. Twelve (11.1%) twin pregnancies were delivered by vaginal delivery, and 96 (88.9%) by cesarean section (C/S). No statistical difference was observed in terms of blood loss when the C/S and vaginal delivery groups were compared. When compared in terms of hospitalization time, it was found that the hospitalization period was shorter in the vaginal delivery group. Conclusion: The clinical results of our study are similar to the current literature. In our study, what we evaluated differently from the literature is blood loss and hospitalization time between C/S and vaginal delivery. There was no difference between C/S and vaginal delivery in terms of blood loss, and it was observed that the hospitalization period of patients who had vaginal delivery was shorter.
目的:评估我院2016年1月至2020年12月期间多胎妊娠的结局。材料与方法:选取2016年1月至2020年12月在Muğla大学培训与研究医院妇产科门诊分娩的6567名孕妇,共纳入107例多胎妊娠。在这些回顾性评估的孕妇中,106名是双胞胎,1名是三胞胎。结果:双绒毛膜双胎共87例(80.18%),双绒毛膜-单羊膜双胎共11例(10.37%),单绒毛膜-单羊膜双胎共8例(7.54%)。早产76例(71.69%),足月分娩30例(28.3%)。双胎妊娠经阴道分娩12例(11.1%),剖宫产96例(88.9%)。当C/S组和阴道分娩组比较时,出血量没有统计学差异。对比住院时间,发现阴道分娩组住院时间更短。结论:本研究的临床结果与现有文献相似。在我们的研究中,我们与文献评估不同的是C/S和阴道分娩之间的出血量和住院时间。C/S与阴道分娩在出血量方面没有差异,并且观察到阴道分娩患者住院时间更短。
{"title":"Son Dört Yılda Üçüncü Basamak Hastanemizde Doğumu Gerçekleşen Çoğul Gebelik Sonuçlarının Değerlendirilmesi","authors":"Özge ŞEHİRLİ KINCI, Mehmet Ferdi Kıncı, Leyla Taştan, Ercan Saruhan, A. A. Sivaslıoğlu","doi":"10.38136/jgon.1094804","DOIUrl":"https://doi.org/10.38136/jgon.1094804","url":null,"abstract":"Aim: We aimed to evaluate the outcomes of multiple pregnancies between January 2016 and December 2020 in our hospital, which is a tertiary center. \u0000Materials and Methods: 107 multiple pregnancies were included in the study among 6567 pregnant women who were delivered between January 2016 and December 2020 in Muğla University Training and Research Hospital Obstetrics and Gynecology Clinic. Of these retrospectively evaluated pregnant women, 106 were twins and 1 was triplet. \u0000Results: It was determined that 87 (80.18%) twin pregnancies were diamniotic-dichorionic, 11 (10.37%) were dichorionic-monoamniotic, and 8 (7.54%) were monochorionic-monoamniotic, respectively. 76 (71.69%) of the deliveries were with preterm delivery and 30 (28.3%) of the pregnant women were delivered at term. Twelve (11.1%) twin pregnancies were delivered by vaginal delivery, and 96 (88.9%) by cesarean section (C/S). No statistical difference was observed in terms of blood loss when the C/S and vaginal delivery groups were compared. When compared in terms of hospitalization time, it was found that the hospitalization period was shorter in the vaginal delivery group. \u0000Conclusion: The clinical results of our study are similar to the current literature. In our study, what we evaluated differently from the literature is blood loss and hospitalization time between C/S and vaginal delivery. There was no difference between C/S and vaginal delivery in terms of blood loss, and it was observed that the hospitalization period of patients who had vaginal delivery was shorter.","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124482662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IVF/ICSI YAPILAN HASTALARDA GEBELİK VE YENİDOĞAN SONUÇLARININ ÖNGÖRÜLMESİNDE HCG TETİKLEME GÜNÜNDEKİ ESTRADİOL'ÜN DEĞERLENDİRİLMESİ: RETROSPEKTİF KOHORT ÇALIŞMASI
Pub Date : 2022-08-22 DOI: 10.38136/jgon.1106410
K. Erdoğan, Inci Kahyaoglu, S. Dilbaz, Iskender Kaplanoglu, Oya Aldemir, Ceren Kamaci, Emine Utlu Özen, Nazlı Tunca Şanlier
Aim: Our aim was to investigate the value of serum estradiol (E2) on human chorionic gonadotrophin (hCG) trigger day in predicting pregnancy (ongoing pregnancy with live birth, abortion, iu ex, chemical pregnancy) outcomes and neonatal birth weight. Material-Methods: This retrospective study consisted of two groups: Group 1: Women who had live birth, labor after 22 gestational week (n= 417). Group 2: Women with clinical pregnancy: intrauterine ex, abortus, biochemical and anembryonic pregnancy (n=260). Demographic characteristics (maternal and paternal ages, body mass index (BMI), gravidity, abortion, and living child) were recorded. Clinical indications (male factor, diminished ovarian reserve...), duration of ovulation stimulation, day 3 (D3) E2, follicle stimulating hormone and luteinizing hormone levels, antral follicle count, total doses of stimulating agents, progesteron and estradiol levels on trigger day, number of oocytes retrieved, number of mature oocytes, endometrial thickness on trigger and oocyte pick-up day were compared between the two groups. Binary Logistic Regression, (Backward LR model) was used to determine the factors affecting the risk of not having a live birth. Results: Totally 677 pregnant women were included in the study. We found increased live birth rate in pregnant whom E2 level was higher on the trigger day. There was a statistically significant relation between E2 level on trigger day and newborn weight in live birth (p=0.005) It was determined that the male factor and age of the women are an important parameter that affect not having a live birth (p
目的:我们的目的是探讨血清雌二醇(E2)对人绒毛膜促性腺激素(hCG)触发日的预测妊娠(活产妊娠、流产、妊娠、化学妊娠)结局和新生儿出生体重的价值。材料-方法:本回顾性研究分为两组:第一组:活产,妊娠22周后分娩的妇女(n= 417)。第二组:有临床妊娠的妇女:宫内妊娠、流产、生化妊娠和无胚妊娠(n=260)。记录人口统计学特征(母亲和父亲的年龄、体重指数(BMI)、妊娠、流产和活产儿)。比较两组患者的临床适应症(男性因素、卵巢储备功能减退等)、促排卵持续时间、第3天(D3) E2、促卵泡激素和黄体生成素水平、窦腔卵泡计数、刺激药物总剂量、触发日黄体酮和雌二醇水平、回收卵母细胞数量、成熟卵母细胞数量、触发日子宫内膜厚度和卵母细胞提取日。使用二元Logistic回归(Backward LR模型)来确定影响未活产风险的因素。结果:677名孕妇被纳入研究。我们发现E2水平在触发日较高的孕妇的活产率增加。触发日E2水平与活产新生儿体重有统计学意义(p=0.005),确定男性因素和女性年龄是影响未活产的重要参数(p=0.005)
{"title":"IVF/ICSI YAPILAN HASTALARDA GEBELİK VE YENİDOĞAN SONUÇLARININ ÖNGÖRÜLMESİNDE HCG TETİKLEME GÜNÜNDEKİ ESTRADİOL'ÜN DEĞERLENDİRİLMESİ: RETROSPEKTİF KOHORT ÇALIŞMASI","authors":"K. Erdoğan, Inci Kahyaoglu, S. Dilbaz, Iskender Kaplanoglu, Oya Aldemir, Ceren Kamaci, Emine Utlu Özen, Nazlı Tunca Şanlier","doi":"10.38136/jgon.1106410","DOIUrl":"https://doi.org/10.38136/jgon.1106410","url":null,"abstract":"Aim: Our aim was to investigate the value of serum estradiol (E2) on human chorionic gonadotrophin (hCG) trigger day in predicting pregnancy (ongoing pregnancy with live birth, abortion, iu ex, chemical pregnancy) outcomes and neonatal birth weight. \u0000Material-Methods: This retrospective study consisted of two groups: Group 1: Women who had live birth, labor after 22 gestational week (n= 417). Group 2: Women with clinical pregnancy: intrauterine ex, abortus, biochemical and anembryonic pregnancy (n=260). \u0000Demographic characteristics (maternal and paternal ages, body mass index (BMI), gravidity, abortion, and living child) were recorded. Clinical indications (male factor, diminished ovarian reserve...), duration of ovulation stimulation, day 3 (D3) E2, follicle stimulating hormone and luteinizing hormone levels, antral follicle count, total doses of stimulating agents, progesteron and estradiol levels on trigger day, number of oocytes retrieved, number of mature oocytes, endometrial thickness on trigger and oocyte pick-up day were compared between the two groups. \u0000Binary Logistic Regression, (Backward LR model) was used to determine the factors affecting the risk of not having a live birth. \u0000Results: Totally 677 pregnant women were included in the study. We found increased live birth rate in pregnant whom E2 level was higher on the trigger day. There was a statistically significant relation between E2 level on trigger day and newborn weight in live birth (p=0.005) It was determined that the male factor and age of the women are an important parameter that affect not having a live birth (p","PeriodicalId":119624,"journal":{"name":"Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129602219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1